Gene ACP5-3 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold PPPL
Superfamily PPPL
Family PAP
Subfamily ACP5
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP094_AA protein Get Run
MbreP094_AA_48-276 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PAPL_pd Subfamily PAPL 49-269 1.2e-93 304.2 In-house 1-212 (212) alignment 
Range on Protein: 49-269
Range on HMM: 1-212/212.0
LLLGDWGGTNKSPYTEPGQVACAASLGEVAANLDADIALLLGDNFYDSGVHgDEHDARFEETFENVYTADSLqDIPFYVVAGNHDWLGNVSAQIGYSTLS
|.||||||....|||.. |.|.|..||.||..|.|...| ||||||..||. |..||||.||||.|.||.|| ..|.||||||||. ||||||| ||.||
lvlgDwGgleeapyttaaqeavakelgkvaeeleaqfvlalGDnfYekGvk.dvddarfketfedvftaesl.qvpwyvvagnHDykGnvsaqiaYskls

ARWIFPYYFYTRSFSWPGEtrNVTMDIVFIDTILLSGNSDLleDKfgeLQGPADPVMAETQWAFIEAALNSSQADYLFTAGHYPVWSGCQHGPTLSLVRK
.|| || ..||.||..|..  |.|...|.|||.||.|.||   .|   |.||.|  .||.|||..|..|..|.||||..|||||||| ..|||| .||..
krWkfpslyytksfkipds..natvqlvlidtvllcgksdd..lk...legpvdvslaeeqwawleeeLkaseadylivaGhypvwsvaehGptkiLvkr

LKPMLEQYKATGHLAGHDHCL
|||.||.|..|..|.||||.|
LkPlLekynvtaylsGhDhnl
ACP5 49-268 1.7e-58 189.6 In-house 2-198 (198) alignment 
Range on Protein: 49-268
Range on HMM: 2-198/198.0
LLLGDWGGTNKSPYTepgqvACAASLGEVAANLDADIALLLGDNFYDSGVHgDEHDARFEETFENVYTADSLQdIPFYVVAGNHDWLGNVSAQIGYSTLS
|..||||........     |.|...|.||..||.|. | |||||||.||. ...| ||.|.||..|||.||| .|.|||.||||..||||||| |.  |
lvvGDwGrkgeynqs.....avakqmgkvaekldidfvlslGDnfyddGvt.svddprfkesfekiytakslq.vpWyvvlGNHDyrgnvsaqieyakrs

ARWIFPYYFYTRSFSWPGETRNVTMDivfidtillsgnsdllEDKFGELQGPADPVMAETQWAFIEAALNSSQADYLFTAGHYPVWSGCQHGPTLSLVRK
 .. ||...|. |..   .. . ...                ..|  . .....  .||.|.. .|.||..|.||... .||.||.| ..||.| .||..
kdsrfpslryslskkevvtelftekk................deksdqrevaerekyaeeqlkwlekalakstadwkiVvGHhpvySigehgdtkelver

LKPMLEQYKATGHLAGHDHC
|.|.|..||.. .|.|||||
llpllkkykvdaYlnGHdHc
Metallophos Calcineurin-like phosphoesterase 49-268 2.8e-16 53.4 Pfam-A 4-199 (200) alignment 
Range on Protein: 49-268
Range on HMM: 4-199/200.0
LLLGDWGGTNKSPYtepgqVaCAASLGEVAANLDADIALLLGDNFYDsGVHGDEHDARFEetfenVYTADSLQDIPFYVVAGNHDWLGNVSAQIGYSTLS
|..||..|..  ..        .  | ..||. ..|. | |||...  | ...|  |..       .    |..||.... |||.. .  ||   . . .
lvigDlHgglddle.....d.lllillkiaaeekpdlvlflGDlvdr.gdwssetlalld.....ylvlklllpipvfllrGNHesdpgnsaygflleql

ARWIFPYYFYTRSFSWpgetrnvtmdivfiDtiLLSGNSDLLEDKFGELQGPADPVMAETQWAFIEAALNSSQADYLFTAGHYPVWSGCQHGPT----LS
 ..  ... .   ..               .    ...          | .  ..  .| |. . .| .. ...|. .  .| |..|  ..| .    |.
kdlrglangeeeyenl..............k..itllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddigself

LVRKLKPMLEQYKATGHLAGHDHC
  . | . ||.|. .  | ||.|.
gpdalekllekygvdlvlrGHtHk
subfamily_ACP5_pd Subfamily ACP5 78-268 1.4e-11 36.7 In-house 20-187 (189) alignment 
Range on Protein: 78-268
Range on HMM: 20-187/189.0
AANLDADIALLLGDNFYDSGVhgdeHDARFEETFENVYTaDSLQDIPFYVVAGNHDWLGNVSAQigystlsarwifpyyfyTRSFSWPGETRNVTMDIVF
... ..|... .||  |. .     ....  ..| |.   .    .|. |..|||.   |.||                  .. || | ..   ..|.  
eeaneldliihvGDlaYalka....kneavwdefmnlie.plaskvPymvsiGnhesdsnfsay.................kkrfsmpsknewYsfdygp

IDTILLSGNSDLLEDkfgelqgpadpvmaETQWAFIEAAL----NSSQADYLFTAGHYPVWSGCQHGPT----LSLVRK-----LKPMLEQYKATGHLAG
. .| || . |  ..              ..|....|. |    |... ......|| |..   ...       .||||     | ..|..||    |.|
vhfislstevdfslg..............seqykWLekdLkeannrkktpwiivmgHrPmYcsnkdeddctkeetlvrkglresledllykykvdlalsg

HDHC
|.|.
HeHs
Metallophos_2 Calcineurin-like phosphoesterase superfamily domain 82-227 2.1e-06 19.9 Pfam-A 25-115 (156) alignment 
Range on Protein: 82-227
Range on HMM: 25-115/156.0
DADIALLLGDnfydsgvhgdehdarfeeTFENVYTADSLQDIPFYVVAGNHDwlgnvsaqigyS----------Tlsarwifpyyfytrsfswpgetrnv
..|..| .||                   .|   . . |.|||...| ||||                      .                         
evdlilhaGD..................lvepeevvelledipvlavrGnhD...........eaelpkelavel.........................

tmdivfidtILLSGNSDLLEDKFGELQGPADPVMAETQwaFIEAALNSSQADYLFT
         .| . .... .|... . |   .|  ...  .....|....||..| 
.........llaaaaleiegdrvllvhgtplsvqssee..elaellkeagadlvfl