Gene ACP2-1 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HP
Superfamily HP
Family HP2
Subfamily ACP2
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP116_AA protein Get Run
MbreP116_AA_22-397 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_ACP2_pd Subfamily ACP2 23-396 2.8e-113 371.1 In-house 8-360 (361) alignment 
Range on Protein: 23-396
Range on HMM: 8-360/361.0
ELKLVQILFRHGDRTALRDLPGVSQP-SDWPEGYGQLTALGMQMHYNVGAYFRKRYIQDLSFIDAAYNHEQIVVRSTDADRTLMSAQAQLAGWFPVETSV
.||.||.|||||||..|...|  .   ..||.|.||||..|||..|..| ..||||..|..|.|| ||..|| |||.|..|||||||..|||.|| ||.|
kLkfvqvlfRHGdRsPlntypndkykedewpqglGqLTeeGmqqqyeLGkfLrkrYvedtkfldakynpkqiyvrSsdvnRTlmSaqsvlaglfppetgv

LGPPDILWRPVPVHTRPVEDDLLLRswSQGVCPRYDQLEANWNQTQGWHDKNNQIVDplacqavhlpadqnctvaqYLSALEPISQiAPLDLDSLWQISD
  |... |.||||||...|.|||||  ..  |||||.| ....... .......  .                   .|..|.  ..  ..||.. .|.||
dypdeqeWqpvPvhtvseeedlllr..akknCprydellqeakespevkklleenke...................lleklsestg.edidlenfyqlsd

TLLCRRM-HN-LSMPDYANHsdvgEAsYSLLRSLEDWGMYAMFD-----SVPKRRLSGGPVLQELISNMQAALQ---DSSMPRVFLYSGHDTNLAAVLEA
||.|.|. .| |..|..||.    |. .. |..|.|. . |.|.     .  ...|.|||.|.||..||...|.   .... ..||||.|||.|||.|||
tlicerkyanelnlpewand....el.fekleeladkvkeaefglnnektrelkklrgGpllnellenmkeklkceekkkklklflYSaHDttlaalLea

LqtDHFRARAPPYASCLIVELHV-EDDTPFVRIVFKNESAIDAPehpghTLTVKTCEH-SDCPLSEFVKVMSPILPTDMTVDCQAAT
|  ..|. .||||||..||||.  .|..|.|.....||.. |.|     .||...|.. .|||||.| |...|..|.|..  |.|.|
L..gifekkappyasaiivElyeeddgkplvkvlyrnetskdpp.....eltlpgCkgeedCplskfkkivkpfipddvdelCeakt
0053031 Phosphoglycerate mutase-like 23-392 5.2e-74 242.5 In-house 2-340 (342) alignment 
Range on Protein: 23-392
Range on HMM: 2-340/342.0
ELKLVQILFRHGDRTALRDLP-GVSQPSDWPEGYGQLTALGMQMHYNVGAYFRKRYiqdLSFIDAAYNHEQIVVRSTDADRTLMSAQAQLAGWFPVETSV
|||.|..|.|||.|| |  .|  . .   .| |.|.|| ||....|..|...||||   |....  ||.....|||.| ||||.|||| ||| || |.. 
eLkqvivlvRHGaRtPlskgpldplnewfypcgageLTplGreqayelGrrlrkrY...lgllpstynpdevyvrssdvdRtlqSAqaflaGlfppegtp

LGPPDILWRPVPVHTRPVEDDLLLRSwSQGVCPRYDQLEANWNQTQGWHDKNNQIVDplacqavhlpadqnctvaqylsALEPISQIAPLDLDS----LW
. .|.. | |.|.|| |   | ||.  .   ||..|.| ... ... . . .... .                       |. .|..  |.|..    ..
ilnpllgwqpipihtepessdalllp.nydpcpafdkllkealaseevkelleryle......................llqklskglgltlsdlldlvs

QISDTLLCRRMHNLSMPDYANHSDVGEASYSllRSLEDWGMYAMFDSVPKRRLSGGPVLQELISNMQAALQDSSMPRVFLYSGHDTNLAAVLEALQTDhf
 . |.||..  |.|..|.. .  .  |. .    .|. . .| .. . . ..|.||| |.|............. ....||..|||..||.| ||.    
dlydlllyelahglplppwctlftleelkal..yaldllyyyglgpgnelaklaggpllneilarleekisgpldlklylyfahdttiaallsaLglf..

RARAPPYASCLIVELHVEDDTPFVRIVFKNESaidapEHPGHTLTVKTCEHsDCPLSEFVKVMSPILPTDMTVDC
  . |||||.|..||.  .....||... ...      .. ..|... |.   ||||||.......||.|.   |
ddqlPpyasnlvfElyedpgeyyVrvlynggt.....lseplvlplpgcdg.lcplsefkelvkkllpgdfeklC
0049226 Phosphoglycerate mutase-like 23-392 2.7e-73 240.1 In-house 2-340 (342) alignment 
Range on Protein: 23-392
Range on HMM: 2-340/342.0
ELKLVQILFRHGDRTALRDLPG-VSQPSDWPEGYGQLTALGMQMHYNVGAYFRKRYiqdLSFIDAAYNHEQIVVRSTDADRTLMSAQAQLAGWFPVETSV
.||.||.|.|||||| |  .|  . ..  |. |.|.|| ||....|..|...||||   |....  ||.... |||.| ||||.|||| ||| || |.  
kLkqvqvliRHGdRtPlakgpldflnewfwgcglgeLTplGreqayelGrrlrkrY...lgllpstynpdevyvrssdvdRtlqSaqaflaGlfppeltp

LGPPDILWRPVPVHTRPVEDDLLLRSwSQGVCPRYDQLEANWNQTQGWHDKNNQIVDPLACQAVHLPADqnctvaqylsalepisqiaPLDLDSLWQ-IS
  .|.. | |.|..| |   | ||.  ..  ||..|.|  .. ... . . ...| | |   . .|. .                   . .| .... . 
ilvplldwqpipiitepesndtllll.pydscpnfdkllkellkseevqlfleeildllkklskllgln...................lstlsdvadtly

DTLLCRRMHNLSMPDYANHSDVGEASYSllRSLEDWGMYAMFDSVPKRRLSGGPVLQELISNMQAALQDSSMPRVFLYSGHDTNLAAVLEALQTDHfrAR
|.||..  |.|..|.. .     |. .    .|  . .| .... . .||.||| |.|.......|.. .| ....||..|||..||.| ||.  .   .
dlllyelahglplppwcslftleelkal..yaldllyyygigygeeiarlaggpllneilarleeaiegpsdlklylyfahdttiaallsalglfd..dq

APPYASCLIVELHVEDDTPFVRIVFKNESAiDAPehpgHTLTVKTCeHSDCPLSEFVKVMSPILPTDMTVDC
 |||||.|..||.  |....||... ...  . |    .||... | .. |||.||.......||.|.   |
lPpyasnlvfElyecdgeyyVrvlynggvl.slp....vtlplpgc.dglcpldefkelvkkflpgdfeelC
0046349 Phosphoglycerate mutase-like 23-394 2.2e-72 237.4 In-house 6-392 (409) alignment 
Range on Protein: 23-394
Range on HMM: 6-392/409.0
ELKLVQILFRHGDRTALRD---LPGV---SQPsDWPEGYGQLTALGMQMHYNVGAYFRKRYIQdLSFIDAA--YNHEQIVVRSTDADRTLMSAQAQLAGW
|||.||.|||||.|| . .   ||..    ..  .| |.||||.||....|..|...||||.. |....    ||...| |||.| ||||.|||| ||| 
eLkqvqvlfRHGaRtPtkklsflpnwpginwt.ngpcgagqLTplGreqayelGkrlrkrYvd.lgLlpsnslynpdeiyvrssdvdRtlqSAqaflaGl

FP-VETSV-----LGPPDILWRPVPVHTRPVE-----DDLLLRSWSQgvCPRYDQLEANWNQT-QGWHDknnqIVDPLACQAVHlPADQNCTVAQYLSAL
||  . ..      . .|... |.|..| |..     || ||...|   ||..|.| ... .. . . .    .. ..|.. ..   |..... ..|.. 
fpplggeivpllrqdlldppfqpipidtvpiseddalddtllppdsl..cpaldkllkenlkslsevle....flvdealldle.lldetkdllkklaer

EPIS--QIAPLDLDSLWQ-ISDTLLCRRMHNLSMPDYANHsdVGEASYSLLRSLEDWGMYAMFDSVPKRRLSGGPVLQELISNMQAALQDSS------MP
  ..   .   |.....  . ||||... |.|..|.. .   . .  .  |. | |. .| ...| . ..|.||| |.|.......|.....       .
lnselpglnltdpldvasllydtllyetahglplppwcdl..ftpeelkvlayladleyyylygsgelaklaggpllneilarledaisgknpvtfpldl

RVFLYSGHDTNLAAVLEALQTdhFR-----ARAPPYASCLIVELHV--EDDTPFVRIVFKNEsaidapehpghTLTVKTCEHSdCPLSEFVKVMSPILPT
...||..|||..||.| ||.   |       . |||||.|..||.   .|....||... ..           .|..  |    ||||||.. ....|| 
klylyfaHdttiaallsaLgl..fdrlfrssdippyasnlvfElyecpsdgeyyVrvlyngg...........plplpgcgeg.cplsefkellkkrlpg

----DMTVDCQA
    |    |. 
cgltdfdklCpl
0048946 Phosphoglycerate mutase-like 23-397 1.3e-71 234.8 In-house 40-414 (447) alignment 
Range on Protein: 23-397
Range on HMM: 40-414/447.0
ELKLVQILFRHGDRTAL-----------------------------RDLP-GVSQPSDWPEGYGQLTALGMQMHYNVGAYFRKRYiqdLSFIDaayNHEQ
|||.||.|||||.|| .                             .| .  ....  || |.||||.||....|..|...||||   |....   | ..
elkqvqvlfRHGaRtPtkkylkgleplldllknanvlelggdlsflndwkyqlkneplwpcglgqLTplGreqlyelGkrlrkrY...lgllp...npse

IVVRSTDADRTLMSAQAQLAGWFPVEtsvlgpPDILWRPVPVHTRPVEDDLLLRSwsqgVCPRYDQLEANWNQtQGWHDKNNQIVDPLACQAvhlpadqn
| |||.| ||||.|||| ||| || |      |.. . |.|.|| |   | ||.      ||....|  .. . . ... .... . |. ..        
iyvrssdvdRtlqSaqaflaGlfppe......pplgyqpipihtvpssndnlllp....sCpafkellkkela.eelkellkellerlkkll........

ctvaqylsalepisQIAPLDLDSLWQISDTLLCRRM-HNLSMPDyanhSDVGEASYSLLRSLEDWGMYAMFD-SVPKRRLSGGPVLQELISNMQAALQDS
              .   |.|.... . |.||. .. |.|| .     | . .  .  |. |.|. .| ..  . . .||.||| |.|.......|....
..............gglnltlsdvydlydlllyetaihglsplc....slftpeelevleyladlefyyeygygdelarlaggpllneilarledaisgd

SmpRVFLYSGHDTNLAAVLEALQTDHFRARAP----------------PYASCLIVELHVE------DDTPFVRIVFknesaidapehPGHTLTVKTCEH
|  ...||..|||..||.| ||.  ...   |                ||||.|..||.        |....||...            | .|... |..
s..klylyfaHdttiaallsaLglfddelplpadnlpfnrlfrsseivPyasnlvfElyecpsslpsdgeyyVrvly...........ngeplplpgCgs

S---DCPLSEFVKVMSPILPtDMTVDCQAATP
.    |||..|.. ....|| |    |.. ..
gpgglCplddFkellkkflp.dweklCgltls
0049059 Phosphoglycerate mutase-like 23-392 1.7e-71 234.4 In-house 42-434 (435) alignment 
Range on Protein: 23-392
Range on HMM: 42-434/435.0
ELKLVQILFRHGDRTALRDL---------------PGVSQP------SDWPEGYGQLTALGMQMHYNVGAYFRKRYiQDLsfidaaYNHEQIVVRSTDAD
|||.||.|||||.|| .  |               . .. |       ..| |.|.||.||....|. |...|||| ..|      ||.....|||.| |
elkqvqvlfRHGaRtPtsklikklealwekllslltypngplsflndwnyplgageLTplGreqayelGkrlrkrY.gfL......ynpdevyvrssdvd

RTLMSAQAQLAGWFPVE--TSVLGPPDILWRPVPVHTRPVEDDLLlrswSQGVCPRYDQLEANWNQTQGWHDKNnqivdplacqavhlpadqNCTVAQYL
|||.|||| ||| || |  .| | .|.. . |||..|..  .|.|    .   ||..|.|  .. ... . .                    .  ....|
RtlqSaqaflaGlfppeilgsqllnplnvyqpvpietvdsdndtl....pydscpafdellkellasdeflelf..................lerilkll

SALEPISQIAPLDLDSLWQI--SDTLLCRRMHNLSMPDYANHSDVGEASYSLLRSLEDWGMYAMFDsvPKRRLSGGPVLQELISNMQAALQDSS------
. | |.  . | |. .|. .   ||||... |.|..| .  ...     .. | .|| . .|   |  . ..|.||| |.|.......|....|      
qellpglgltpsdvldlydlckydtlllgyahglplpfcslfteeelevleyladlefyylygygd..eiaklaggpllneilarledaingdstnlnlt

----------MPRVFLYSGHDTNLAAVLEALQTDHFRARAP-------------------PYASCLIVELHVEDD--TPFVRIVFkNEsaidapehpgHT
           ....||..|||..|..| ||.    .   |                   ||||.|..||.  .|  ...||... |.          ..
ldsnpatfpldlklylyfaHdttiapllsaLglfddqlplpadntpfpeldrlfrtseivPyasnlvfElyecpdgneyyVrvly.ng..........kv

LTVKTCEHS---DCPLSEFVKVMSPILPTDMTVDC
|... |...    |||..|.. ....||.|    |
lplpgcgsgpgglCplddFkelvkkflpgddfdeC
0047369 Phosphoglycerate mutase-like 23-393 2.1e-71 234.3 In-house 43-437 (438) alignment 
Range on Protein: 23-393
Range on HMM: 43-437/438.0
ELKLVQILFRHGDRTA--------------LRDLPgVSQPSD--------WPEGYGQLTALGMQMHYNVGAYFRKRYiQDLsfidaayNHEQI-VVRSTD
|||.||.|||||.||               | .    . . .        .| |.|||| ||....|..|...|||| . |       |.|.. .|||.|
elkqvqvlfRHGaRtPtksklkkleplwellenat.typsgplsflndwlgpcgagqLTplGreqayelGkrlrkrY.glL.......npedvlyvrssd

ADRTLMSAQAQLAGWFPvETSVLGPPDILWRPVPVHTRPVEDDLLLRSWSQGVCPRYDQLEANWNQTQGWHDKNnqivdplacqavhlpadqnctVAQYL
 ||||.|||| ||| || ...   ...|||.|.|.||.| .|| ||...... ||..|.|  .. ... . ..                       ...|
vdRtlqSAqaflaGlfp.pegtgelapilwqpipihtipesddfllnllpsdscpafdellkeflasdeflell.....................lkdil

SALEPISQIAPLDLDSLWQISDTLLCRRMHNLS--MPDYANHSDVGEASYSLLRSLEDWGMYAMF---DsvPKRRLSGGPVLQELISNMQAALQDSS---
. |. . ..  |. ...... |.. .   .| .  .|.. . | . .  .  |. |.|. .| ..   .  . ..|.||| |.|.......|....|   
krlkkllpglnltpsdvldlydlcaydtlangyaglplspfcslftpeelevleyladlefyylygygn..elaklaggpllneilarledaingkstnl

-------------MPRVFLYSGHDTNLAAVLEALQTDHFRARAP-------------------PYASCLIVELHV--EDDTPFVRIVFknesaidapehP
              ....||..|||..||.| ||.  ...   |                   ||||.|..||.   .|....||...            
nltldsngvtfPldlklylyfaHdttiaallsaLglfddtwplpglpldkialnrlfrsseivPyasnlvfElyecpsdgeyyVrvly...........n

GHTLTVKTCEHS---DCPLSEFVKVMSPILPTDMTVDCQ
|..|... |...    |||..|.. ....||.|    |.
gkvlplpgcgsgpgglCplddFkelvkkllpgdfeelCg
0048439 Phosphoglycerate mutase-like 23-385 3.9e-71 233.3 In-house 8-391 (391) alignment 
Range on Protein: 23-385
Range on HMM: 8-391/391.0
ELKLVQILFRHGDRTALRDLPGVSQP------SDWPEGYGQLTALGMQMHYNVGAYFRKRYIQdLSFIDAAY--NHEQIVVRSTDADRTLMSAQAQLAGW
|||.||.|||||.||.. ..| . .|        .| |.|.||.||....|. |...||||.. |....  |  |.... |||.| ||||.|||| ||| 
elkqvqvlfRHGaRtPtssypnkldpllnkllpngpcglgeLTplGreqlyelGrrlrkrYvd.lgllpskytlnpsevyvrssdvdRtlqSAqaflaGl

FPvE-------TSVLGPPDILWRPVPVHTRPVEDDLLLRSWSQgVCPRY------DQLEANWNQTQGWHDKNnqivdplacqavhlpaDQNCTVAQYLSA
|| .       . |. . |.|. |.|..| |  .|||| . .. ..||.      ..|.. .|.. |..  .                ...... .... 
fp.plgltvilvivvesedpllnplpintcplledlllldals.alprfylseilerlaevlnrvlglnlta................edvlslfdlcak

LEPISQIAP---LDLDSLWQISDTLLCRRMHNLSMPDYANHSDVGEASYSLLRSLEDWGMYAMFDSVPKRRLSGGPVLQELISNMqaALQDSSMPRVFLY
.  .    .    .| .|. . ||||..  |.|..|...... . .  .  |..| .. .| ...| . ..|.||| |.|.....  . . .| |...||
etaalgsllklssplcdlftlydtllyeyahglplpewltdellspellkqladlvnelyyyltgsgeiaklaggpllneilddl..vangpsdpklyly

SGHDTNLAAVLEALQTDHFRA----RAPPYASCLIVELHVE--DDTPFVRIVFKNE--------SAIDAPEHPGH-TLTVKTCEHS---DCPLSEFVKVM
..|||..||.| ||.  .. .      |||||.|..||.    |....||... ..        . .|  | . . .|... |...    |||..||...
faHdttiaallsaLglfndtlplpadlppyasnlvfElyecpsdgeyyVrvlynggtldlprdltlldldefllrlvlplpgcgsgpgglCplddFvelv

SPILP
....|
kkrip
His_Phos_2 Histidine phosphatase superfamily (branch 2) 23-345 2.5e-46 151.2 Pfam-A 1-346 (347) alignment 
Range on Protein: 23-345
Range on HMM: 1-346/347.0
ELKLVQILFRHGDRTALRDLP--------------------GV--S-----QPSDWPEGYGQLTALGMQMHYNVGAYFRKRYIqdlSFIDAAYNHEQIVV
||| |....|||||| . . .                    .   .     .  ... ..|.||  |.......| ..|.||    ....  .. |.. .
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp...gllrdhltyedvki

RSTDADRTLMSAQAQLAGWFPVET---SVLGPPDILWRPVPVHTRPV---EDDLLLRSWSqGVCPRYDQLeanwnqtqgwhdknNQIVDPLACQAVHLPA
||.. .|.|.|||| .||... |         .   . .....| .    ... |||  .   ||....                . |.  ....|.  .
rssserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellrega.escpafawp..............pikvekrvvelvnklk

DQNCTVAQ-YLSALepISQIAPLDLDSLWQISDTLLCRRM--HNLSMPDYANHSDVGEASYSLLRSLEDwgMYAM-FDSVPKRRLSGGPVLQELISNMQA
 . .. ..  ||||  ... ..|. .. |.  .. ...    ... .|. ...     . .. |..||   .|     . . ..  |...|..|..... 
kvmdenlakrlsal..ctgednllfkerweklfreffeeekfdiskipelydtmkydalhnrqledlee..lyklygigdeeklkigllllnpllkkils

ALQDSS---MPRVFLYSGHDTNLAAVLEALQTDH----FRARAPPYASCLIVELHV-EDDTPFVRIVF
.|...      ...||..||......| ||. .      ... .||||....||.  ......||..|
dleetqpsrhaklrlyfthDshiytllnaLgleekiareaspelpyasqivfelyedsekkfyvrllf
His_Phos_2 Histidine phosphatase superfamily (branch 2) 23-345 2.5e-46 151.2 In-house 1-346 (347) alignment 
Range on Protein: 23-345
Range on HMM: 1-346/347.0
ELKLVQILFRHGDRTALRDLP--------------------GV--S-----QPSDWPEGYGQLTALGMQMHYNVGAYFRKRYIqdlSFIDAAYNHEQIVV
||| |....|||||| . . .                    .   .     .  ... ..|.||  |.......| ..|.||    ....  .. |.. .
eLkgvvvviRHGdRtPkqkfkksvtsekfisllklknvlekkghfpgtkrkeklqlilkwgglThsGrkqaeelGeqlrqrYp...gllrdhltyedvki

RSTDADRTLMSAQAQLAGWFPVET---SVLGPPDILWRPVPVHTRPV---EDDLLLRSWSqGVCPRYDQLeanwnqtqgwhdknNQIVDPLACQAVHLPA
||.. .|.|.|||| .||... |         .   . .....| .    ... |||  .   ||....                . |.  ....|.  .
rssserRvlaSAqafaaGllgpegelllsirkdllddsnaakdtmdevkkklkellrega.escpafawp..............pikvekrvvelvnklk

DQNCTVAQ-YLSALepISQIAPLDLDSLWQISDTLLCRRM--HNLSMPDYANHSDVGEASYSLLRSLEDwgMYAM-FDSVPKRRLSGGPVLQELISNMQA
 . .. ..  ||||  ... ..|. .. |.  .. ...    ... .|. ...     . .. |..||   .|     . . ..  |...|..|..... 
kvmdenlakrlsal..ctgednllfkerweklfreffeeekfdiskipelydtmkydalhnrqledlee..lyklygigdeeklkigllllnpllkkils

ALQDSS---MPRVFLYSGHDTNLAAVLEALQTDH----FRARAPPYASCLIVELHV-EDDTPFVRIVF
.|...      ...||..||......| ||. .      ... .||||....||.  ......||..|
dleetqpsrhaklrlyfthDshiytllnaLgleekiareaspelpyasqivfelyedsekkfyvrllf
subfamily_HP2-Group1_pd Subfamily HP2-Group1 56-397 1.4e-32 104.6 In-house 93-421 (422) alignment 
Range on Protein: 56-397
Range on HMM: 93-421/422.0
GQLTALGMQMHYNVGAYFRKRYIQDlSFIDAAYNHEQIVVRSTDADRTLMSAQAQLAGWFPVETSVLGPpdilWRPVPVHTRPVEDDLLlrSWSQGVCPR
.|||  | . .   |  .|| |...  |. ....  .. .|| |  ||..|||| . | .| .| .        . |...||    | .       .||.
aqltleGykqqelnGqilrkvyvdt.GflkssldssevylrsddesrtilsaqalilGmypqdtkaedr....aqvvdlytrdklfdsi..eanadlcpk

YDQLEANWNQTQGWHDKNNQIVDPLACQaVHLPADQNCTV---AQYLSALEPISQIAPLDLDSLWQISDTLLCRRMHNLSMPDYANHSDVGEASYSLLrs
  . . .. ... | .. . |  .|  . |.     | ..   .   .   ||.    ||.|.| .. | |   . ||...||   .  . ..   ||  
lseyntqflksdtwlnhlkgitkellle.vskalGsnkslgsggcshtlylpiavtrkldidnledlvdclithqchnaaipdkltedlakrgldell..

lEDWGMYAMFDSVPKRRLSG-GPVLQELISNMQAALQDSSMPRVFLYSGHDTNLAAVLEALQTDHFRarAPPYASCLIVELHVEDDTPFVRIvfkNESAI
   .    .. || |    | | .|...  ... .|.  .. .  ||||||| |  .| ||. |.|.   ||||| |..||     .| .      . |.
.yrsysslkypsvekyarvGiGfllkdiwkevnesltGedlrkfllysGhdttliqllsalnvdefk..wppyasllllellevstapaast...pqyav

DApEHPGHTLTVKTCEHSDCPLSEFVKVMSPILPTDMTVDCQAATP
    . |. ...  |.  .|.. .| . .| ..| | . ||.. ..
rv.lynGklkklpfcdanecsyeqfeaylstviphddaedckvsdn
subfamily_ACP6_pd Subfamily ACP6 220-394 1.3e-16 52.3 In-house 210-373 (376) alignment 
Range on Protein: 220-394
Range on HMM: 210-373/376.0
SDTLLCRRMHNLSMPDYANH--SDVGEASYSLLRSLEDWGMYAMFDSVpkrRLSGGPVLQELISNMQAALQDSSM-PRVFLYSGHDTNLAAVLEALQTdh
 | .  |. |||..|.  ..    . .   . |. |   |  .  ...   .|| |.||.|...|...| .. .  ... ||| ||| | ..| ||.   
rDniaArlaHnlkvppilkdvidliekhAveelvvlleggdrpekeil...klsvGkvlkeilenlekakekeiparklrLysaHDttlmtLLlalgv..

FRARAPPYASCLIVELHVE-DDTPFVRIVFKNESaidapehpghtLTVKTCEHSDCPLSEFVKVMSPIL-PTDMTVDCQA
|  . ||.|. .|.||. . ..  |||......            | .. .|.  .||  | ......  | |.. .|. 
FDdkWPpfaadvileLyedkageyfvrvlYqeke...........lrlrgseedlvPlekFkallavlvlpkdyaaeCkl
subfamily_ACP6_pd Subfamily ACP6 56-118 2.6e-16 51.2 In-house 76-138 (376) alignment 
Range on Protein: 56-118
Range on HMM: 76-138/376.0
GQLTALGMQMHYNVGAYFRKRYIQDLSFIDAAYNHEQIVVRSTDADRTLMSAQAQLAGWFPVE
||||. |||  ...|   ||||..|..|.   .| .....|||. .||| ||.  .|| .  .
GqLtkvGmqqvfdLGrkLrkrYvedikfLsqefnpqevyiRstnieRtlesarclvaGLygki
subfamily_PXYLP1_pd Subfamily PXYLP1 216-378 3.6e-13 40.5 In-house 235-397 (419) alignment 
Range on Protein: 216-378
Range on HMM: 235-397/419.0
LWQISDTLLCRRMHNLSMPdYANHSDVGEASYSLLRSLEDW-GMYAMFDSVPKR--RLSGGPVLQELISNMQAALQDSSMPRVFLYSGHDTNLAAVLEAL
. .  |.||.   ||.|.| . ..  |    .  | .|.|        .|  |   .|   |.|....|.|. . .  . ..  ||||||  |  ...||
isnpvdalltvlChnvslP.crreGcvepshvdvlhkladelsqrsakksyyklsGllraypllrdivsrmlkiieGvdkekfvlysghDvtlrplvaaL

QTdhFRARAPPYASCLIVELHVEDDT--PFVRIVFKNESAIDAPEHPGHtlTVKTCEHSDCPLSEFVK
.    .|| . ||| |. ||.  . .   ..|....     .  .        |. ..  |||...|.
gl..seartiayasrlvfelyrreaskeyylrvlynGkDvtqkvdfCeg..dskrskkdlCPlenlvr
DUF1180 Protein of unknown function (DUF1180) 394-496 7.7e-09 24.0 Pfam-A 48-161 (163) alignment 
Range on Protein: 394-496
Range on HMM: 48-161/163.0
AATPSPT----TRASS--STTTKNVPASTIDPT--SADAA-NKRDLTVTAVVVAICLALAVAATFFI-LFRRRQRRMRTIGTNIKYTS--RSLAAPLsVV
|..|.||    | ...  ..  |.  .|. ..   | ..  . ..|.  |.||.. .. ||.. | .  .| |.|. .|   ..  |.  .   .||   
alpPgptpanptalleadakkGkasetssggalavspsplsrdkpllkralvVlvvvsaavivyfvlrtvrtrrrnkKtrkYgvldTnienlEltPL.ee

DDDDEEEDVFSSNYP
||.|... .| .|.|
DDeddDsTlFDanqp
subfamily_PXYLP1_pd Subfamily PXYLP1 56-118 3.3e-08 24.1 In-house 104-168 (419) alignment 
Range on Protein: 56-118
Range on HMM: 104-168/419.0
GQLTALGMQMHYNVGAYFRKRYIQDLSFI--DAAYNHEQIVVRSTDADRTLMSAQAQLAGWFPVE
||||  |.  | .||  .|| | . | ..  .  .. ...|. .|   ||| || | | | .| .
gqLtqkGvvqhLevGdllrkvYakklklLlkpnelssDevvlettrkrrtlqsalallygllpka
subfamily_MINPP1_pd Subfamily MINPP1 56-160 5.9e-07 20.7 In-house 90-185 (420) alignment 
Range on Protein: 56-160
Range on HMM: 90-185/420.0
GQLTALGMQMHYNVGAYFRKRYIQDLSfidAAYNHEQIVVRSTDADRTLMSAQAQLAGWfpVET-SVLgppDILWRPVPVHTRPVEDDLLLRSWSQgvCP
..|.| | . .....  . .|. . ..   . ||.... ..||.  ||. |||| . |   .|| .||   ..   .| . .   |.| |||  ..  |.
kslvaqgqeeleelakrlarrfpalfe...evynpdsfsfastakkRtvksaqaFaeGL..setgevl...gdefnivlqeiseqesdklLrffds..Ck

RYDQLE
.|..  
kyknkv
Herpes_gE Alphaherpesvirus glycoprotein E 397-499 1.4e-06 16.9 Pfam-A 318-427 (439) alignment 
Range on Protein: 397-499
Range on HMM: 318-427/439.0
PSPTTRASSSTTTKNVPASTIDPTS-ADAANKRDLTVTAVV--VAICLALAVAATFFILFRRRQRRMR---TIGTNIKYTSRSLAAP-LSVVDDDDEEED
|. ...|.|........  . . ..   | ... |.. |.|  .|. |.......  ....||.|. .   . ... .|||     .  .| .|...|..
PragaaadseesdppatpapsaepakpeartapyllllaavlgaavlllvvlllvlvcvtkrrrrkayekrlspfspvYtsLPtnelvedvsedeesede

VFSSNYPNAP
 ....  . .
evdvdeeeea