Gene TIM50 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily TIM50
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP093_AA protein Get Run
NvecP093_AA_149-274 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TIM50_pd Subfamily TIM50 150-275 2.1e-62 200.9 In-house 1-126 (126) alignment 
Range on Protein: 150-275
Range on HMM: 1-126/126.0
TLILEMTDVLVHPEYDRKSGWRFRKRPGVEFFLNQLAPLFEIVVFTHEVGFSASPVIDGIDPHQMIMYRLFRDATKYIKGTHVKDLSGINRDLKKVIVID
||.||..|||||||...|.||||.|||||..||.|||.||||||||.| |..|.|.|| .||.|.||||||||||||..|.|||||| .||||.||||.|
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldPkqlimyrlfrdatkyvdGehvkdlsklnrdlskvivvd

CNKAATELNERNAIILKKWEGNPADT
..|....|...||..||||||| .|.
ldkksvklqpenalalkkweGnaddk
NIF NLI interacting factor-like phosphatase 149-296 2.1e-35 114.0 Pfam-A 1-159 (159) alignment 
Range on Protein: 149-296
Range on HMM: 1-159/159.0
YTLILEMTDVLVHPEYD-----------RKSGWRFRKRPGVEFFLNQLAPLFEIVVFTHEVGFSASPVIDGIDP-HQMIMYRLFRDATKYIKGTHVKDLS
.||.|.. ..||| . .           .|. ... ||||.. ||..|.  .|.|.|| .    | ||.| .|| .... .||.|. ... .|..|||||
ktLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKdLs

GINRDLKKVIVIDCNKAATELNERNAIILKKWEGN-PADTTLVDLLPLLQTIAtsGVDDVR
 ..|||..|...| .. . ||...|.| .... |. . ||.| .|||.|. ..   .||||
llgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfleale..ksddvr
CPDc_SM00577 150-274 8.1e-29 92.5 In-house 4-145 (146) alignment 
Range on Protein: 150-274
Range on HMM: 4-145/146.0
TLILEMTDVLVHP----------EYDRK-----SGWRFRKRPGVEFFLNQLAPLFEIVVFTHEVGFSASPVIDGIDPHQMIMYR-LFRDATKYIKGTHVK
.|.|.. ..|||           |  ..       ... |||.|. ||...| |||.|.|| .    |....| .||.....|| |.|..... || ..|
vLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkrllkyrvlyRqdcrlvkgkllk

D-LSGINRDLKKVIVIDCNKAATELNERNAIILKKWEGNPAD
| || ...||.||..|| ....|..|..||.  |..  .. |
ddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
subfamily_SCP_pd Subfamily SCP 172-275 5.6e-25 79.8 In-house 39-142 (142) alignment 
Range on Protein: 172-275
Range on HMM: 39-142/142.0
FRKRPGVEFFLNQLAPLFEIVVFTHEVGFSASPVIDGIDPHQMIMYRLFRDATKYIKGTHVKDLSGINRDLKKVIVIDCNKAATELNERNAIILKKWEGN
  ||| |. ||.... |||.|.||  .   |.|| | .| .... .||||..  . ||..||||| . |||||||..|   |.  . . ||. .. |  .
vlkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvlrarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspasyifhpenavpveswfdd

PADT
..||
kedt
subfamily_DULLARD_pd Subfamily DULLARD 170-275 8e-22 69.6 In-house 46-152 (153) alignment 
Range on Protein: 170-275
Range on HMM: 46-152/153.0
WRFRKRPGVEFFLNQLAPLFEIVVFTHEVGFSASPVIDGIDPHQ-MIMYRLFRDATKYIKGTHVKDLSGINRDLKKVIVIDCNKAATELNERNAIILKKW
..  ||| |..||.. .  ...|.||  .   |..|.| .| .. ..  |..|.     .|...|||| .. ||..||..|    | . |  ||| .| |
fyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaipiksw

EGNPADT
  .| ||
lsdpsdt
subfamily_CTDSPL2_pd Subfamily CTDSPL2 172-273 4e-21 67.5 In-house 38-140 (142) alignment 
Range on Protein: 172-273
Range on HMM: 38-140/142.0
FRKRPGVEFFLNQLAPLFEIVVFTHEVGFSASPVIDGIDPHQM-IMYRLFRDATKYIKGTHVKDLSGINRDLKKVIVIDCNKAATELNERNAIILKKWEG
 |.|| .. ||.... |||...||      |  ..| .||..  | .||||.   ...|...|||| . |||.|.|..| .  |  ..  | | .. |  
vrlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayqlenGipieswfe

NPA
.  
den
subfamily_FCP1_pd Subfamily FCP1 166-254 1.2e-06 20.7 In-house 39-129 (146) alignment 
Range on Protein: 166-254
Range on HMM: 39-129/146.0
RKSGWRFRKRPGVEFFLNQLAPLFEIVVFTHEVGFSASPVIDGIDPHQMIMY-RLF-RDaTKYIKGTHVKDLSG-INRDLKKVIVIDCNKAA
.|  .  ..||... ||..|..|.|. ..| .    |. .   .||.. .   |.. ||     . ...|.|.  ...| . |..||  .. 
ekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrd.elldassktkklkklfptddsmvviiDDredv