Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PPP4C_pd | Subfamily PPP4C | 5-292 | 1e-184 | 605.4 | In-house | 1-288 (288) | alignment | ||
Range on Protein: 5-292
Range on HMM: 1-288/288.0
SDLDRQIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRY
|||||||||||.||||.|.|||.|||||||||||||||||||||||||||||||||||.||||||||||.|||||.||||||||||||||||||||||||
sdldrqieklrrcelikeeevkalcakareilveesnvqrvdspvtvcgdihgqfydllelfkvggdvpetnylflgdfvdrgfysvetfllllalkvry
PDRITLIRGNHESRQITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDIQ
|||||||||||||||||||||||||||.||||..|||||.|.||||||.||||...|||||||||||||||.||||||||||||.||.||||||||||..
pdritlirgnhesrqitqvygfydeclrkygsanvwryctevfdylslaaiidgkifcvhgglspsistldeirsidrkqevphegplcdllwsdpedae
GWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAAPQD
||.|||||||||||||||.|.|.||||.||||||||||||||.||||.|||||||||||||||||||||||||.|...|.|||||...
gwavsprgagylfgsdvveqfneandielicrahqlvmegyklhfnekvltvwsapnycyrcgnvaaileldeeldkdfkifeaaaae
|
|||||||||
subfamily_PPP2C_pd | Subfamily PPP2C | 5-291 | 2.9e-156 | 512.0 | In-house | 2-288 (290) | alignment | ||
Range on Protein: 5-291
Range on HMM: 2-288/290.0
SDLDRQIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRY
.|||..||||..|. ..|.|||.|| ||.||| .||||| | .|||||||.||||.|| ||||.||..|||||||.||.||||.||||| || ||||||
kdldklieklkeckqleesevkelcekakeilskesnvqevkcpvtvcgdvhgqfhdllelfkiggkspdtnylflgdyvdrgyysvetvtllvalkvry
PDRITLIRGNHESRQITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDIQ
..|||..||||||||||||||||||||.|||. .||.| ...||||.|.|..|...||.||||||||.|||.||..|| |||||.||.||||||||.| .
keritilrgnhesrqitqvygfydeclrkygnanvwkyftdlfdylpltalvdeqifclhgglspsidtldkiraldrlqevphegplcdllwsdpddrg
GWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAAPQ
|||.||||||| || |. ..| .|.. || ||||||||||.| ... | |..||||||||||| |||||||..||..| |..||.
gwgisprgagytfgkdisekfnktngltliarahqlvmegynwshdrnvvtifsapnycyrcgnqaailelddklkysflqfdpapr
|
|||||||||
subfamily_PPP6C_pd | Subfamily PPP6C | 6-293 | 6.3e-153 | 501.0 | In-house | 1-288 (290) | alignment | ||
Range on Protein: 6-293
Range on HMM: 1-288/290.0
DLDRQIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYP
.||. || ..|. ..|...|.||.. ..|.|||||| | ||||||||||||||||.|||. ||.||||.|.|.|||||||.||.||| .||.||..||
eldkwielakkckylpendlkklcdlvldllleesnvqpvsspvtvcgdihgqfydleelfrtggqvpdtsyvflgdfvdrgyysletftrlltlkakyp
DRITLIRGNHESRQITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDIQG
|||||.||||||||||||||||||||.|||. ..|.||...|| |...||||..|.|||||||| . |||||| |.| ||.||.|..|||.||||||..
dritllrgnhesrqitqvygfydeclnkygnanawkyctkvfdlltiaaiideqvlcvhGglspdvktldqirvieraqeiphkgafcdlvwsdpedvet
WGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAAPQDV
| |||||||||||| |. .... |...|||||||||.||.|..|.| . ||||||||||||||||.||.|... .||. .|.| |..
wavsprgagylfgskvtkefvhinnlklicrahqlveeglkymfdeklvtvwsapnycyrcgnvasilaledaeereaklfkavpdee
|
|||||||||
subfamily_PPG1_pd | Subfamily PPG1 | 7-292 | 2.4e-135 | 443.6 | In-house | 1-299 (300) | alignment | ||
Range on Protein: 7-292
Range on HMM: 1-299/300.0
LDRQIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPD
||. .|||...||. | ||.|. | .|.||.||||... ||||| ||.||||||. |.||.||.||||||||.||.||||.||||| ||..||.|||
ldecleklqkaellpevtvkeltdklkellvkesnvieirspvtvvgdvhgqfydvleifkiggqvpdtnylflgdyvdrglysvetisllivlklryps
RITLIRGNHESRQITQVYGFYDECLKKY-GSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPE----
||||.|||||||||||||||| |||.|| | .||.| .||||||.|.||||. ..|||||||||. ..|||. .|| .|||..| ..||||||||
ritllrgnhesrqitqvygfyteclrkyggnsrvwkylteifdylvlaaiideeiycvhgglspsvlsidqikvldrfrevpnegaladllwsdpeennn
------DIQG--WGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAAPQD
| .| . ||.||||| .| ||| .. ||.. | |||||..|||. .|.. . |||||||||||||| |.|||| |...| | ..|.||..
ptldhpdregqhfvvsqrgagysygkdvvekflrnndmnriirahqlcnegyqilfdnklstvwsapnycyrcgnkasilelyekderyfnvyeeapes
|
|||||||||
0045823 | Metallo-dependent phosphatases | 4-294 | 8.2e-122 | 400.1 | In-house | 27-329 (473) | alignment | ||
Range on Protein: 4-294
Range on HMM: 27-329/473.0
CSDLDRQIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVR
.|||. || |....|..|.....|. .|.||| .|.|..... ...|.||||||..||..|.. | |.....|.||.|||| .|.|...||||||..
lldldlliehlkkegllpeedllklldeakeilkkepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvDrGpdslevlelllalkik
YPDRITLIRGNHESRQITQVYGFYDECLKKYgSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDI
||....|.|||||.|.....|||.||.|.|| .. ..... | ...| |.|.|......|||||||....|||||.|.| .|.|.||...|||||||...
ypgnvfllrGNHElrllnglygfgdetleky.gedlyeeflewlrslPlaaviggkilfvHGGlspdlplldqireierpleipddgllldllwsdPwed
QG--------WGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNET------VLTVWSAPNYCYRCGNVAAILELDEHLkREFTIFEAA
| .| |||||||||| |.| . |..|||.|.|. |.|||...|. ..||.||||||.|.|| ||.|..||.| ..|..|...
dgdgllrlrffgnsprgagylFgpdaveeflkkngldlivrGHthvpeGyellfdgkvigiDtgiTvfSApnYcgrggnlaAvlvidedl.isfiqfdps
PQDVR
|....
phpli
|
|||||||||
PPP_3 | 20-287 | 3.9e-121 | 396.2 | In-house | 2-270 (271) | alignment | |||
Range on Protein: 20-287
Range on HMM: 2-270/271.0
ITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ
..|.|.|.|. |..||| .|||......|||||||||||..|| ||||.||..|.|.|||.||.|||| .|.|..|||||||..||....|.||||||||
lsenelkelvkklkeilekesnlveisapvtvcGDiHGqldDLlelfknggpspetkYlFlGdyVDrGkkslEvlllLlalkikypkevhLlRGnhEsrq
ITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDL-LWSDPEDIQGWGVSPRGAGYLFG
|..||||..|.|||.|. .|.... |.|..|.|.|.||..|..|||||||||..||||....||.|||..|...|| |.||||. .|.. |.||||.|||
inkvYgFkkevlkkkggkkvykklqevFelLplaalidekvlvvHGGlspsiksldqikklerkievpeegklldlllssdpekeeglenskrGagllFg
SDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFE
.||... . .|...||.|||.|..|||. .... |.||.||||||.|..|..|||.|.|.|..||...|
pdvteefleknkLkliiRaHelkeeGyeilhdgkvvtvfSapnycerasnagailkleealtsefkqle
|
|||||||||
PPP_1 | 21-274 | 9.3e-114 | 372.1 | In-house | 2-263 (264) | alignment | |||
Range on Protein: 21-274
Range on HMM: 2-263/264.0
TEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
.|.|...|. |..|.|..|.|...|....||||||||||.|| .||||||..|.|||||.||.|||| .|||..|||||||..||....|.||||||||.
eeeelaelkkklkellnkeenllevseeitvcGDiHGqfdDLlklfkvggpspetnYlFlGDyVDRGkdSvEilllLlalklkypkelfllRGNHEsrqv
TQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDL--------LWSDPEDIQGWGVSPRG
|.||||..|.|||..| .........||.|.|.|.||.....|||||||....||||| ..||.|||..|..||| |..|.|. ... |.||
tkvygFkkEvlkkkyskeiyktltdvFdvLplaalidekilivHGGlspeldlldqirkerrktevpeegklcdllekdvdillsddkeqeeavansiRG
AGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILE
||||||.||..... .|...||.|||....|||.......|.|..||.||.....| .|...
agylfgkdvtekflqknnlkliiRaHevkeeGyeflkkrkvvtifsasnyyeegsnrgayvk
|
|||||||||
0049330 | Metallo-dependent phosphatases | 5-292 | 2.7e-113 | 371.0 | In-house | 15-302 (309) | alignment | ||
Range on Protein: 5-292
Range on HMM: 15-302/309.0
SDLDRQIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRY
|.||..||.|... |..|.|...|. ||.||| .|.|..... ...|.||||||..||..|.. | .|.....|.||.|||| .|.|..|||||||..|
slldllielllklkllseeellllllkakeilksepnllelsmrivviGDiHGqlddLlrllekigfppedrlvflGDlvdrGpdslevlllllalklly
PDRITLIRGNHESRQITQVYGFYDECLKKYGsITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DI
||...|.|||||.|.....|||.||.| ||| . .|... . ...| | |.|.....||||||||.. .|||||...| .|.|.||..|||||||| ..
pdnvfllrGNHElrllnglygfgdetlrkyg.aelweefldwlrslplaaviggkilcvHgGlspdlllldqirelerpleipldgllcdllwsdplpir
QGWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAAPQD
|.. .|||.|..|| ..| .. |..|||.|.|..|..||...|.. ..||.||||||.|.||..|.||.||.|...|..||..|.
egfapnprglgvvfghtaverflkkngldliirghgavfgGyltffdgklitvfsapnycgrlgnlgavleidedlvisfllfepvpll
|
|||||||||
0053225 | Metallo-dependent phosphatases | 5-290 | 4.3e-110 | 360.6 | In-house | 7-292 (293) | alignment | ||
Range on Protein: 5-290
Range on HMM: 7-292/293.0
SDLDRQIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRY
..||..|| |... |..|.|...|. .|.|||..|.|..... ...|.|||||...||..|.. | .|.....|.||.|||| .|.|...||||||..|
llldllielllllkllseeelllllleakeilkkepnllelsmriyviGDiHGnlddLlallekigfppedrlvflGDlvdrGpdslevlelllalklly
PDRITLIRGNHESRQITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDIQ
||...|.|||||.......|||.||.| |||. .|... . ...| |.|.|......|||||||..|.|||||.|.| ...|..|...||||||| ..
pdnvvllrGNHElmllnglygfgdetlrkygaaelwdelldwlrslplaaliggkilfvHgGlspdlslldqireinrplriplegllldllwsdpdlws
GWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAAP
||. |.||.|..|| ..| .. .|..|||.|.||.|..||...|.. ..||.|||||..|.||..|.|.|||.|...|..|.. .
gwlpsyrglgvvfghtavlrflkkngldliirghqvvpdgylpwfdgklvtvfsapnylgrlgnlgavlaldeglvwgfklfapvl
|
|||||||||
subfamily_PPP1C_pd | Subfamily PPP1C | 19-288 | 6.7e-107 | 349.9 | In-house | 9-278 (282) | alignment | ||
Range on Protein: 19-288
Range on HMM: 9-278/282.0
LITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR
..|.|...|..||||||.... . ... ||...||||||..|| ||. .| |..||||.||.|||| |.|| .||||.|..||... |.||||||
klkeaeieallkkareillsqpilleleaPvkivgdihGqyadllrlfetsgaPpesnylflGdyvdrGkqsletivlllaykikypenlfllrGnhesa
QITQVYGFYDECLKKYGsITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DIQGWGVSPRGAGYLF
.|...||||||| ..|. |..|. ..|..| |.|..|....||||||||... |.|||.| | |||..| .||||||||. ...||. . || . |
sinriyGfydeckrrys.iklWktftdvfnclPlaalvdekilcvhGGlspelksleqirkiqrPlevpekgllcdllWsdpdkevlgwsendrGvsftf
GSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEA
|.|||... . ||.|||.||||.| .||... .. ..||.|||||| . .| .|.|..||.|. .|.|. .
gkdvvekflqkndldlivrahqvvedGyeffakrqlvtvfsapnycgefdnagavlsvdeellvsfqilkp
|
|||||||||
PP2Ac_SM00156 | 21-288 | 1.4e-105 | 345.2 | In-house | 2-269 (271) | alignment | |||
Range on Protein: 21-288
Range on HMM: 2-269/271.0
TEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
...||..|. ...||| .|.|. .|..||||.||||||..|| .|.. .| .|...|.|.||.|||| .|.|. |||.|||..||....| ||||||...
skeevlelleevkeilkqeknlvevsapvtvvGdihGqlddllrllelageppeekyvFlGdYVDRGpqsiEvillLfalkilypekvvLLRGnHEsssv
TQVYGFYDECLKKYgSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDP-EDIQGWGVSPRGAGYLFGS
...|||..|. || . .. . |.|..|.|.|..|....|.||||||....||.||...| .| |..|...||||||| .. .|. | ||....||.
nkiygfeeevkrky.gkeiyekfeeafsllPlaalvdskilcmhGGlspeleslddirklkrvkekpeegllidllwsdpeqkekgfqpskrglsvvFge
DVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEA
|.| .. .|...||.|||..|.|||.. ... ..|..||||||....|.||.|.....|| .. ...
davkeflkknnlkliiRahevvdeGyeffadkklvtifsapnycdefsnkaavlkveknlklsieqlke
|
|||||||||
subfamily_Cele-PPP-Subfam4_pd | Subfamily Cele-PPP-Subfam4 | 10-289 | 3.8e-96 | 314.6 | In-house | 14-294 (298) | alignment | ||
Range on Protein: 10-289
Range on HMM: 14-294/298.0
QIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRIT
... . .. |.|..|..|...|..|. . . . ||.|..||||||||. || ||. .| ||.||||.||.|||| ...|. .|||| ||.||...
slsekkltkvikeedveklielakkifkkqkslvevdapikvcGdihGqysdllrlfdkagfppdanylflGdyvdrGrqnlevivlllaykvkypnnff
LIRGNHESRQITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPED-IQGWGV
|.||||| .| .|||||.|| ..| |.... ..|. | | |.| .|..|.|||||. ...|||.|.. | .. ... ||||.|||. ..||
llrGnheceainrvyGfyeeckrrykslrlyaefqdvfnalpltaliggrilcmhGGlskklksldqlrelkrpfdskeeslaidllwadpenavkgwae
SPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAA
. ||... ||.|||.. ||||..||||.| .||.. . ..|..|||.|| . | ||....||.|. |... .
nsrGvsvvfGedvvkdllekldidlvvrahqvvqdGyeffaekklvtifsaphycgqfdnsaavmkvdeklvvsfevlkpe
|
|||||||||
subfamily_Cele-PPP-4B_pd | Subfamily Cele-PPP-4B | 18-294 | 1.1e-86 | 283.7 | In-house | 22-299 (299) | alignment | ||
Range on Protein: 18-294
Range on HMM: 22-299/299.0
ELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHES
. . |.|...||| |........ . |..|. ||||||||. || .|.. | ||.|.||.||.|||| .|. |||. |..||.|. ..|||||
ksvkeqelqtlcavaksvfasqaslleveapiivcgdihgqysdllrifdkagfppdvnflflgdyvdrgrqnlelitlllcfkikyperffmlrgnhec
RQITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPED-IQGWGVSPRGAGYL
| .|||||.|| |.| | .| . |... |. .| .|..|.|||||| ..||||.| . | |. | ||||.||.. ...| || |.
painrvygfyeecnkrykstrlwsifqdafaampltgligsrilcmhgglspklqtldqlrdltrpqdppnpslgidllwadpdqsvkdwlanvrgvsyv
FGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAAPQDVR
|| ||||. ||||..||||.| .||.. . ..|..||| || . | |||...|| | |.... .|....
fgqdvvadvisrldidlvarahqvvqdgyeffaskklvtifsaphycgqfdnsaaimkvdenlvctfvvlkptpkslk
|
|||||||||
subfamily_PPP3C_pd | Subfamily PPP3C | 19-278 | 3.5e-85 | 279.5 | In-house | 40-312 (452) | alignment | ||
Range on Protein: 19-278
Range on HMM: 40-312/452.0
LITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR
..|... .. .| ..| .|... .|..|.||.|||||||||| .||.|||| .|.|||.||.|||| .|.|. | |.|||. ||... |.|||||.|
rleeeaalkiieeaakllkkektlleveaPitviGdihGqfydllklfevgGdPastkylflGdyvdrGyfsiecvlylyalkiaypstlfllrGnhecr
QITQVYGFYDECLKKYgSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDI-QGW-------GVSP
.|. . | .|| .|| | .|. | | || | |.|..... .|||||||| |..||.|...|| .|.|. ||.|||||||| . . |.
hlteyftfkeeckiky.seevydacmesfdslPlaallnqqflcvhGGlspeikslddikkldrfkeppasGplcdllWsdPledygeekteekfvpnsv
RGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFN------ETVLTVWSAPNYCYRCGNVAAILELDEH
|| |... |... .||. | |||. .||. . . ...|..|||||. | ||.|....
rGcsyfysykavceflqkndllsiiraheaqdaGyrmyrkseatgfPslitlfsapnyldvynnkaavlkyenn
|
|||||||||
subfamily_PPP5C_pd | Subfamily PPP5C | 10-290 | 2.2e-84 | 276.2 | In-house | 24-310 (322) | alignment | ||
Range on Protein: 10-290
Range on HMM: 24-310/322.0
QIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSP----VTVCGDIHGQFYDLKELFKVGGDVPD-TNYLFMGDFVDRGFYSVETFLLLLALKVRY
.|.... . . .| . .. ..|.|.| ... . .. . .||||||||||||| ..|.. | . . ||| ||||||| .|||. |.||..|. |
llelfkkqkklhkkyalkilleakellkklpslveitieetkkltvcGdihgqfydllnifelnGlpseenpylfnGdfvdrGsfsveviltllgfklly
PDRITLIRGNHESRQITQVYGFYDECLKKYGSiTVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSP-SISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDI
|... | |||||| .. ..||| .|. .|| . .| .|.|..| |. .|...|. ||||| |||..| ||| .. |..| ...||||||..
PnhfflsrGnhesdnmnklyGfegevkakyte.kvadlftevfnwlPlahvinekvlvvhGGlfsedgvtlddlrkidrnaqppeegllvellwsdpqea
QGWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILEL-DEHLKREFTIFEAAP
.| . | || | || || .. |...|| |.|.. .|||. . . ..||.|||||| . || .|...| ...|| .|. ||| .
nGrspskrGvgvqfGpdvtkkflkennleliirshevkeeGyevehdGklitvfsapnycdqmgnkgafitlrgddlklkfktfeave
|
|||||||||
subfamily_Cele-PPP-1A_pd | Subfamily Cele-PPP-1A | 17-287 | 8.2e-84 | 274.4 | In-house | 4-281 (284) | alignment | ||
Range on Protein: 17-287
Range on HMM: 4-281/284.0
C-ELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDV------PDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRIT
| .|..|||. .|| .|||.. .|. . ...||...||||||| ||. |... | ...|||.||.|||| .|.| .||.|.|...||...
cqkllkekelielcyrarelfwkeklkleieapvkivgdihgqfedllalldlngwpfvedeakekkylflgdyvdrgpfsievitllfayklllpdkvf
LIRGNHESRQITQVYGFYDECLKKYgSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DIQGWGV
|.||||||| . . |||| || |.| | ... | . |.|.......|.|||.| . |.|. ..| ..| | ..|| |.||| ...|.
llrgnhesrpvnmqygfyleckkry.sealyeafqlafnamplcavvskkiicmhggisedlldlkqldklerpidipdigviadltwadpeaevegyke
SPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFE
|||||| .||.. | ... ..||. ||||.||.||.. . ..|..||| || . |.||.|..||.| ||...
sprgagkvfgakavkeflkkfkldlvvrahqvvmdgyeffadrklvtifsapsycgqldniaavlnvdeelvasftvlk
|
|||||||||
subfamily_Cele-PPP-4C_pd | Subfamily Cele-PPP-4C | 16-294 | 1.4e-83 | 273.3 | In-house | 4-280 (280) | alignment | ||
Range on Protein: 16-294
Range on HMM: 4-280/280.0
NCelITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH
.| | | ..... | ..||. .. . ||.||.||||.|||. || ||. . ||.||||.||.|||| . .| ||||| |||||... ..||||
ac..ikeadidrviekckkiltaqatmvevdapvavcgdlhgqytdllrlfarvsfppdqnylflgdyvdrgrqqlevillllaykvrypnnflilrgnh
ESRQITQVYGFYDECLKKYgSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DIQGWGVSPRGAG
| .| . |||.||. ..| | .. |..| | | |.. |..|.|||||. . .||... . | . ... ||||.||| .. ||. ..||.
evisinrkygfkdevkrry.slalynefqelldslplvalvsgrilcmhgglsqklvslddlaelrrpfdsedeclamdllwadpenkvtgwaensrgvs
YLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAAPQDVR
..||..|| .. |||||.| ||.| .||.. . ..||.|||.|. | ||.| .||.|. | .. | ..|.
vifganvvkdltekldidliarghqvvqdgyeffadkklvtvfsapkylgefdnsaavlivderlivsfevlkpalrevk
|
|||||||||
subfamily_Cele-PPP-Subfam2_pd | Subfamily Cele-PPP-Subfam2 | 18-286 | 3.3e-82 | 268.9 | In-house | 5-274 (281) | alignment | ||
Range on Protein: 18-286
Range on HMM: 5-274/281.0
EL-ITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHE
.. .|..|.... ... |..||... .|.|..| ||.|.|| |||.||.. | ||.. ..|.||.|||| |.|...||..||.||.||| |.|||||
kvqytkeeienvireveaifseekaLveidkPivvvGdlhaqfndlkrlfellgrvpeevlvflgdyvdrgpqslevlillftlkiryrdrivllrgnhe
SRQITQVYGFYDECLKKYGsITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPED-IQGWGVSPRGAGY
.. ..|||| || ||| . .| . |. | .|| |..|| |.|||||| . .||..| . . . .. | . ||||.||.. ..| | ||...
iasvnkiygfyvecvtkyG.eelwalfqrcfnrlpisaliakrvlcmhGGlsPeltaldelrnrpkpirnldrGlviDllwadpdnkveewkassrGssf
LFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIF
.|| .|| . ...|| ||||.|..||. ..||.|.|||| | ||.| .|| |. .. .
tfGknvvddvckrleveliirahqvvqdGyevlsgrklitvfsvpnycafyknaaavlkvdetlgislval
|
|||||||||
PPP_2 | 49-240 | 2.1e-81 | 265.3 | In-house | 1-197 (198) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-197/198.0
VTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKYGSITVWRYCAEIFD
||||||.|||..|| .|||.|...|...|||.||.|||| .|.|..|||||||..||....|.||||||.....||||..|.|||.|. .|.... |.|.
vtvcGDlHGqldDLlilfknglpsperkylFlGdyvDrGkkslEvlllllalklvypkevhLlRGnhEskkvnkvygFkkevlkkkggkkvykklqevfe
YLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDL-----LWSDPEDIQGWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQL
.|.|.|.||..|..||||||..|..||||....||.|.|..|...|| |....|. ... | ||||.|||.||... .|...||.|||..
lLplaalidekvlvvHGGlseeiklldqikkeerkiespeegklldlleeeklsdpkekeellansarGagllfgpdvteelleknklkliiRaHev
|
|||||||||
subfamily_Cele-PPP-4D_pd | Subfamily Cele-PPP-4D | 16-287 | 7.8e-78 | 254.7 | In-house | 19-293 (297) | alignment | ||
Range on Protein: 16-287
Range on HMM: 19-293/297.0
NCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNH
...|||. | .| | ... . .. |..|. ||||||||| || ||. || | .||||.||.|||| .|.|| .|||| ||..| . |.||||
lskviteervlklldlaldvfkaqksmvevnapikvcgdihgqfpdllrlfhrggwpptanylflgdyvdrgrfsietivlllaykvkfpgnlfllrgnh
ESRQITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSP---SISTLDQIRSIDRKQEVpHDGPMCDLLWSDPE-DIQGWGVSPR
| . .|||||.|| |.| |. .. ..|..| |. .| ....|.|||||| ||| .| |.| .| ... ..||||.|| . |. |
ecefvnkvygfyeecqkryqsvrmyaafqdvfnwlpltgliatkilcmhgglsplltkeftldtlrkiersteg.kerlvadllwadpisglsgfmenqr
GAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFE
||| || | | . . ..||.|||||.| .||.. ..|..||| || . |.||.. ||.|. | |.
gagcgfgrdavlklcsefkldlvcrahqvvqdgyeffagrklvtifsaphycgqfdncaafmscdeklqcsfeilr
|
|||||||||
subfamily_PPZ_pd | Subfamily PPZ | 20-287 | 2.2e-76 | 250.2 | In-house | 25-292 (300) | alignment | ||
Range on Protein: 20-287
Range on HMM: 25-292/300.0
ITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQ
. ..|. |.| ||||... . .. . .| . ||.|||. || || | | .||||.||.|||| |.|| ||||. |..||. . |.||||| .
lknseilqicikarelflaqpallelspsvkivgdvhgqyadllrlftkcgfppsanylflgdyvdrgkqsletillllcykikypenffllrgnhecan
ITQVYGFYDEClKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPEDI-QGWGVSPRGAGYLFG
.|.|||||||| |. | .|. . |. | |.||. ..||||||||| . ..|.|| . | .|| | . ||||||| | . | || | .
vtrvygfydec.krrcnikiwktfvdtfntlplaaivagkifcvhgglspvlnsmdeirhvvrptdvpdfglindllwsdptdssnewednergvsycyn
SDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFE
. .. .||.|||| .| .||.. . ...||.|||||| | |.. . | | | ...
kvainkflnkfgfdlvcrahmvvedgyeffndrslvtvfsapnycgefdnwgavmsvsegllcsfelld
|
|||||||||
PPP_4 | 49-240 | 2.5e-76 | 249.1 | In-house | 1-196 (197) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-196/197.0
VTVCGDIHGQFYDL-KELFKVGGDVP-DTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKyGSITVWRYCAEI
|||.||||||..|| .|.|.||. . ...|.|.||.|||| .|.|..|||||||..||....|.||||||......|||..|.|.| . ...... ..
vtvvGDiHGqlddlllkllkngglpseersyvflGDyVDRGkdslevlllLlalklvypkevvllRGNHEskslnllygfkkevlek.hgkeilkklqdv
FDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVP-HDGPMCDL-LWSDPE-DIQGWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQL
||.|.|.|.||..|..||||||.....||.|. |.||.|.| ... ..|| |||||. . .|. | ||||.|||.||. . .|...||.|.|.|
fdllplaalidekvlvvhgglsdelesldkierierkiespleeekrkdlllwsdpreaqeglansvrGagllFgpdvtekfleknnlkliirshel
|
|||||||||
PPP_5_Dcr2 | 49-240 | 5e-75 | 244.9 | In-house | 1-198 (199) | alignment | |||
Range on Protein: 49-240
Range on HMM: 1-198/199.0
VTVCGDIHGQFYDL-KELFKVGGDVP-DTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKYGSITVWRYCAEI
||||||.|||..|| .||| ||| . ...|.|.||.|||| .|.|..|||||||..||....|.|||||..|....|||..|.|.||.. ..... ..
vtvcGDlHGqlddlllilfkeggdpseerlyvFlGDyVDrGkdslevlllLlalklvypkevhllrGNHEdeqlneiygftkevlskyhgkkiykilsdv
FDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVP-HDGPMCDL-LWSDPE-DIQG-WGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQL
||.|.|.|.||..|..|||||||.| ...... |.||.|.| ..| ..|| |||||. . .| . | ||||.||| ||. . |...||.|.|.|
fdwlPlaalidekvlvvhgglspeiksiellekierkieipeekgekadlllwsdprdaqegcklnseRGagllfgpdvtekfleknnlkliirshel
|
|||||||||
subfamily_Cele-PPP-2B_pd | Subfamily Cele-PPP-2B | 17-284 | 1.5e-74 | 243.9 | In-house | 3-270 (280) | alignment | ||
Range on Protein: 17-284
Range on HMM: 3-270/280.0
CELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHE
|...| .|. . |..||||. ..|. | |||| |. |.. || . | ||. . .|.||.|||| .| ..||..||.|| ||| |.|||||
cnvmtgheiiaiirmveaifmeesnlceaeapikvigdihaqyqdmnrlfdligrvpeeklmflgdyvdrgpqgievlillfclkiryrdriyllrgnhe
SRQITQVYGFYDECLKKYGsITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPED-IQGWGVSPRGAGY
. . ..|||| || ||| . .| .|. . .|..| .||.|.|||||| . || || | | | | . ||||||| . .|| | || |
tpsvnkiygfyvecqykyg.vglwwdfqscfnrmpmsgliskrvlcmhgglspelinldtirniprpcepldrgllidllwsdptnkgegwfhsirgisy
LFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFT
.|| || | . .|||| ||||.| .||. ..||.| |||| . | ||.. |. |. |
mfgkgvveqacksleidliirahqvvqdgyemmagrrlitvfsvpnycaqftnaaavvclnanlqvsfq
|
|||||||||
subfamily_Cele-PPP-Subfam3_pd | Subfamily Cele-PPP-Subfam3 | 13-287 | 1.5e-73 | 240.2 | In-house | 3-280 (287) | alignment | ||
Range on Protein: 13-287
Range on HMM: 3-280/287.0
KLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIR
| . ...|.. .. |..||| . . .|..|.|..||||||. || .|. | |...|||.||.|||| |.| |||..||..|| .. |.|
kygvldafsdkdilevlekieeileplpalleveapitivGdihGqlddllrifnavGaapkvqylflGdyvdrGakslevslllfslkiaypkkvhllr
GNHESRQITQVYGFYDECLKKYGsITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQE--VPHDGPMCDLLWSDPE-DIQGWGVS
|||| ..| ..|||..| .|.. ... ..|..|.| |....|..|.|||.|| . .||..... . . ..| . ||||.||| | .. .
GnhevkkinklyGfkeelkrkrq.erlykqfndvfselplcarvskrilcmhGGispklksldslkalkkpttplacdeglqvdllwadpekdaktfeln
-PRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFE
|. .|| .| .. ||||| |||... |||.. |.. ..||.||| |. . |..|.. ... |. |. .
kiraisvvfGkkevddllkkldidlivrahevseeGyaflfdkrlvtvfsapyysgedtnlgavvvvskslelsfvvlk
|
|||||||||
subfamily_Cele-PPP-4A_pd | Subfamily Cele-PPP-4A | 19-286 | 2.9e-70 | 229.9 | In-house | 2-271 (284) | alignment | ||
Range on Protein: 19-286
Range on HMM: 2-271/284.0
LITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESR
||. ..|. | .| .|. .. . |.||. .|||||||| || || | .||||.||.|||| . .|| |||.| || .|... ..|||||
lippedvetllfhafsifnkqpmlievnspinicgdihgqfsdllrlfdkngfphranylflgdyvdrgkhcletilllfaykvifpnhffmlrgnhecs
QITQVYGFYDECLKKYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPM-CDLLWSDPEDIQ-GWGVSPRGAGYL
| ..||||.|| ..| .|. .| . |.|.. .|..|.|||.| . . |.|.| | . | . |.||||| ..| || || |.
linkiygfyeecqrrynkpsvyvsfegvfsvmpltalvgqrilcmhggvskmlqnvsqlraikrpfdnpepntlaidilwsdptnfqkgwnpnsrgvsyv
FGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIF
|||| . . .|||. ||||.| .||.. | ..|..||| || . | ||.. ... | | ..
fgsdalrklldrlqidlvvrahqvvqdgyeffanrrlvtifsapfycgqfdnaaavmyvnknlvcsfvvl
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 75-287 | 3.2e-70 | 229.8 | In-house | 101-313 (317) | alignment | ||
Range on Protein: 75-287
Range on HMM: 101-313/317.0
TNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKYgSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTL
.|||.||.|||| .|.| .||.|||..|||...|.||||||| . . |||| |. |.| | ... .| | |.|.......|.|||.| .. |
kkylflGdyvdrGpfsievvillfalkllypdkvfllrGnhesrpvntqyGfyrevkkry.saalyeafqlafnvlplcavvnkkilcmhGGiseelldl
DQIRSIDRKQEVPHDGPMCDLLWSDPE-DIQGWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAIL
.|. ..| ..| | ..|| |.||. ...|. |.|||| .||.. | ... |.||. ||||.|..||.. . ..|..|||.|| . |.||.|
kqldklkrpldipdvGvladltwadpdaevkgykesarGagkvfGakavkeflkkldldlvvrahqvvedGyeffadrklvtifsapsycGqldniaavl
ELDEHLKREFTIFE
..|..|| .....
svdkklkisinvlr
|
|||||||||
subfamily_Cele-PPP-3B_pd | Subfamily Cele-PPP-3B | 11-286 | 7.4e-65 | 211.8 | In-house | 7-286 (290) | alignment | ||
Range on Protein: 11-286
Range on HMM: 7-286/290.0
IEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITL
..| . ...|.. .. |..||| . .| .|... ||||||. .| . |. | |. ..||.||.|||| |.| |||. .|.||. .. |
llkygvldafsdkdileilekieeileplpalleveapivivgdihgqldallryfdavgyppkvkflflgdyvdrgakslevslllfcykiryskkvhl
IRGNHESRQITQVYGFYDECLKKYGSiTVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQ--EVPHDGPMCDLLWSDPED--IQGW
.||||| |.. ..|||..| .| || .|. ..|. ||| | ......|.|||.|. | . . .... . . ..| . ||||.||. .
lrgnhevrkvnrlygfkeelarkrgs.rlwkqyqdvfaelslcarvgrkilcmhggisqkiesweslkalkkprvpltcdeglqvdllwadptrdkddti
GV-SPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIF
. |. .|| ... .. ..|| |||.. ||... |.. ..||.||| |. . |. ||... | |. .....
alnkqraisvvfgkkglddllkklalslivrahevkeegfnflfdkklvtvfsapyysgndtnlgaiatvseslelsivvl
|
|||||||||
subfamily_Cele-PPP-2A_pd | Subfamily Cele-PPP-2A | 21-286 | 6.6e-62 | 202.4 | In-house | 21-289 (307) | alignment | ||
Range on Protein: 21-286
Range on HMM: 21-289/307.0
TEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI
| .|.... .|. |. | . .| |. | ||.|||| || ..| . | |.| |.| ||.||||. |.|. |||.. |. ||. | |.||||| ..
tkeefenviyeaqtifssekalvdidppcvvvgdlhgqfndlinmfillgrppetvyvftgdyvdrgllslecilllftykicypenivllrgnheiarv
TQVYGFYDECLKKYGS--ITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPMCDLLWSDPE-DIQGWGVSPRGAGYLF
. ||||.||. .| |. | .||.| ...|.||||||... ||..| . | | . |.||.||. . | | ||.|. |
nkkygfyeecvtsipkcgeeiwalfqrcfnnlpisaliatkilcmhgglspaltcldelrnhpkpirnpfrgivndmlwadpdpsvfewkassrgsgftf
GSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIF
|..|. . ..|| ||||....|| ..|..||| || | ..| .|| | . |
gtnviddvckrlgveliirahqmcfdgywvlsgrklitifsapmycnfyknagcvlkvdetlgiqlvaf
|
|||||||||
subfamily_Cele-PPP-3A_pd | Subfamily Cele-PPP-3A | 45-287 | 3.7e-56 | 183.7 | In-house | 5-254 (263) | alignment | ||
Range on Protein: 45-287
Range on HMM: 5-254/263.0
VDSPVTVCGDIHGQFYDLKELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKYGSI----TVW
...|. .||| |||. || .|. | |.|||.||.|||| .|.| .||..||. | .. |.||||| . | . |||. | |.. .|.
lqapinicgdthgqyndllrifnacgaatktqylflgdyvdrgghslevimllfslklamprkmhllrgnhelkainknygfhaelkkrfqreevyesvy
RYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRKQEVPHDGPM-CDLLWSDPE-DIQGWGVS-PRGAGYLFGSDVVAQYNAANDIDLICRA
. ..| |. | ||. .|..|.|||.|| . .||.||.| | . |. |||||.||| | .|. | .|| | . ||||| ||
nhfnqvfsymplcaivskrilcmhggisphlkslddiraiplpletakthplacdllwadpekdakgfepnkiraisnvfgkkevddlckrldidlivra
HQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFE
||.| || . . ..||.|| | | ||.. ... |. | ..
hqvveygyaffadrrlitvfsasryqielcnyaavvvvnkmlelsfvqlk
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 76-291 | 2.7e-54 | 177.5 | In-house | 121-336 (339) | alignment | ||
Range on Protein: 76-291
Range on HMM: 121-336/339.0
NYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKYGSiTVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLD
|||.||.|||| .|.| .|| |||. ||||| |.||||||| . |||| | .| . .. ..|. . . |.|.| ..|.|||.| .....
rylflgdyvdrgpfsmevvilltalklaypdriyllrgnhesrsvntsygfyrevnyryda.qlyecfqnmfnvfpfcavinntimcmhggisehltsfn
QIRSIDRKQEVPHDGPMCDLLWSDPEDI-QGWGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILE
|. . | |.| | . || |.||. .|. | ||| ..|| . . |.... | ||.| .||.. ..|..|||||| . | ||..
qfsvfkrpleipdvgvltdltwadpdptekgykpsargasfvfgppalraflkkldlqmvirghqvvedgyeffdgrrlvtifsapnycgqndntaavfs
LDEHLKREFTIFEAAPQ
.|..|| .| .
idkklkisinvfrpesr
|
|||||||||
subfamily_PPPLV_pd | Subfamily PPPLV | 27-278 | 1.9e-53 | 174.6 | In-house | 4-278 (290) | alignment | ||
Range on Protein: 27-278
Range on HMM: 4-278/290.0
QLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDL----KELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQ
|| .| .||..| .. ..||. | ||.||.. || | |...| |. ...||.||.|||| .||| |||||| || .. |.||||| . ...
slcdvavdilaaeerllelksptyvlgdlhgnyrdliyfekvlwrtgvdltpasllflgdyvdrgdfsveliayllalkvlypskvlllrgnhelesvqe
VYGFYDECLKKYGSI--TVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSID---RKQEVPHDG-PM-CDLLWSDPEDIQ-----------
. .. |. |.| || ..||.| |.|.||..|||||.|. .| | .| .|. . . . || |. |.|||||.. .
sieykgegsfkfgdsleevweafnnvfdalplaavidrkvfcvhagipraimtqayisaiqdilerlkddidgaplaldilwsdpaedrdlslrgelvln
-GWG-VSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCgNVAAILELDEH
|. . || |..|..| . .. |... . |||. .|.. . .|||.|. .|| | ||.. .|..
eGfvdndrrGtghvfsedaleaflkrnnlsfvlrahevkekGirlqqkgrlltvfsssrycGss.neaalilvdkk
|
|||||||||
subfamily_Cele-PPP-5_pd | Subfamily Cele-PPP-5 | 20-280 | 4.6e-53 | 173.3 | In-house | 6-291 (302) | alignment | ||
Range on Protein: 20-280
Range on HMM: 6-291/302.0
ITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKV-----------GGDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRI
...|. .|. . | | .|... .. .|||. ||||||| || ... ..|.||.|||| |.| |..|||| || .
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny
TLIRGNHESRQITQVYGFYDECLKKYGSIT---VWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRK-QEVPHDGPMCDLLWSDPEDIQ
|.|||||.. | ||| .| ...| .|. |.| .. |.|.. ....|||||.|| ...|..|..|.| .|| .| |||..|| |.|
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq
GWGVSP----------RGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLK
. . . || ..| | . ...|| |||| . ||.|.. .. .||..|||.| | |.|..| |
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngk
|
|||||||||
subfamily_Cele-PPP-Subfam5_pd | Subfamily Cele-PPP-Subfam5 | 20-280 | 6.9e-53 | 172.8 | In-house | 7-292 (302) | alignment | ||
Range on Protein: 20-280
Range on HMM: 7-292/302.0
ITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVG-----------GDVPDTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRI
...|. .|. . | | .|... .. .|||. ||||||| || ... ..|.||.|||| |.| |..|||| || .
ysksellllieaviellkkektlaeispPvtivGdihGqfedlvrilnarvskeeakkksaysfssdkfvflGdyvdrGsksieciclvfalkvlyptny
TLIRGNHESRQITQVYGFYDECLKKYGSIT---VWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIRSIDRK-QEVPHDGPMCDLLWSDPEDIQ
|.|||||.. | ||| .| ...| .|. |.| .. |.|.. ....|||||.|| ...|..|..|.| .|| .| |||..|| |.|
illrgnhetkainfaygfreelenrlgkkdgkeiwekfnevfsfmplaalvgekilcvhggispklesledikkikrplkevtedslaqdllfadpldvq
GWGVSP----------RGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLK
. . . || ..| | . ...|| |||| . ||.|.. .. .||..|||.| | |.|..| |
llaavsekPkyaknivrglsvvfneaavrdvckrlnlklivrahqmiPeGfkffadkklltifsaprymnesdnkGavlkvdtngk
|
|||||||||
Metallophos | Calcineurin-like phosphoesterase | 48-240 | 2.3e-46 | 151.6 | Pfam-A | 2-198 (200) | alignment | ||
Range on Protein: 48-240
Range on HMM: 2-198/200.0
PVTVCGDIHGQFYDL----KELFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLL--LALKVRYPDRITLIRGNHESRQITQVYGFYDECLK---------
...|.||.||...|| .|.|.... . ...||.||.|||| .| ||. || |.||...|... |.||||||......|||..|.||
rilvigDlHgglddledlllillkiaaeekpdlvlflGDlvdrgdwssetlalldylvlklllpipvfllrGNHesdpgnsaygflleqlkdlrglange
------------------------KYGSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPSISTLDQIrsidrkqevphdgpmcdllwsdpediqgwgv
... ..... |.|..|.| |..|......||.||.| . |.|
eeyenlkitllttsgelyglsglypllgdsaqeeqleeflalplralvdgkilltHgplsssggsgddi...............................
sprgAGYLFGSDVVAQYNAANDIDLICRAHQL
...|||.|.. ...||..|.|.
....gselfgpdalekllekygvdlvlrGHtH
|
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subfamily_PPP7C_pd | Subfamily PPP7C | 4-184 | 1.5e-39 | 128.8 | In-house | 17-203 (383) | alignment | ||
Range on Protein: 4-184
Range on HMM: 17-203/383.0
CSDLDRQIEKLRNCELITEKEVKQLCAKAREILVEESNVQRVDS----PVTVCGDIHGQFYDLKE-LFKVGGDVPDTNYLFMGDFVDRGFYSVETFLLLL
...... ||.... .|. | | .. .|...|.. |..|| . ||||||.||.. || |.| | .. .|.| ||||||| ||| |.||
kdeveklieafkekkllhakyvllilreakkvlkqlpnisrvstaiskevtvcGdlhGklddlllilyknGlpseenpyvfnGdfvdrGkesveillill
ALKVRYPDRITLIRGNHESRQITQVYGFYDECLKKY--GSITVWRYCAEIFDYLSLSAIIDNRVFCVHGGLSPsISTLDQIRSIDRKQ
|| . || . | ||||| . ||| | .|| . . | ..| .| |...||.... ||||.| .. |. . .|.|..
alllvypkevylnrGnhedhilnlryGfikeveskykvhgkkilrlledvfawlplatlidekilivhGGisd.ktdlelldkiersk
|
|||||||||
subfamily_PPP7C_pd | Subfamily PPP7C | 192-289 | 6.1e-18 | 57.7 | In-house | 237-335 (383) | alignment | ||
Range on Protein: 192-289
Range on HMM: 237-335/383.0
MCDLLWSDPEDIQG-WGVSPRGAGYLFGSDVVAQYNAANDIDLICRAHQLVMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLKREFTIFEAA
. |.|||||. .| . . ||.| ||.|| .. . ...|. |.|. .|||.. ...|||..|| || | | . | ..|. .. . |.
vldilwsdpkakeGckpntlrGgGsyfGpdvtkkllqkynlkllirsheckpeGyefvhdkkvltifsasnyyeeGsnrGayvklgkdltprivqyqas
|
|||||||||
subfamily_Cele-PPP-Subfam1_pd | Subfamily Cele-PPP-Subfam1 | 17-70 | 1.8e-14 | 46.7 | In-house | 6-59 (317) | alignment | ||
Range on Protein: 17-70
Range on HMM: 6-59/317.0
CELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVGG
.|..|||. .|| .|||.. .| ....|||..||||||| ||. |... |
qdlfkekelielcyrarelfwkeplkleleapvtivGdihGqfedllalldlnG
|
|||||||||
subfamily_Cele-PPP-1B_pd | Subfamily Cele-PPP-1B | 17-69 | 5e-09 | 28.7 | In-house | 8-60 (339) | alignment | ||
Range on Protein: 17-69
Range on HMM: 8-60/339.0
CELITEKEVKQLCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFKVG
.|. |. .|| .|||.. | . ....|. | ||||||| || .. .
ldlfcaaelaelchrareliwsepiflkleapicvmgdihgqfddllamldmn
|
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subfamily_YNL217W_pd | Subfamily YNL217W | 49-121 | 5.6e-06 | 19.0 | In-house | 12-80 (235) | alignment | ||
Range on Protein: 49-121
Range on HMM: 12-80/235.0
VTVCGDIHGQFYDLKELFK--VGGDVPDTNYLFMGDFVDRGFYSVETFLLLlalkvrYPDRITLIRGNHESRQIT
. | ||.|| . .| ||.. .|| .. ...||....| |||. .. | ..|||| .
llvvGdvhgaYDelieLlddkiggkdenvlvvlvGdlinkGPksvevvsyv......rkdqvkcvkGnheelvll
|