Gene CDC25 in Nematostella vectensis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC3
Superfamily CC3
Family CDC25
Subfamily CDC25
Protein sequence
ID Type Fasta BLAST phosphatome Note
NvecP153_AA protein Get Run
NvecP153_AA_433-546 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_CDC25_pd Subfamily CDC25 435-546 2.1e-50 160.7 In-house 1-113 (114) alignment 
Range on Protein: 435-546
Range on HMM: 1-113/114.0
LINGDYKDEIDEYYIIDCRYPFEFDGGHVKGAINIYTKDEMLKQFIDTPKCK-EGKRVVVIFHCEFSSKRGPDMCRFLRNRDRDIHRPSYPSLFYPELYL
|..|.....|.|..|||||||.|..|||.|||.|.|...|........||.| | || ..||||||||.|||...|.||..||.... .||.|.||||||
llkgefeekiaevliiDcRypyEyegGHikgavnlysreeveeellkkpkvkseekrkiiifhCefsseRgPklarllrevdrelnkeeypkleypelyl

LDGGYKNFFNTCK
|..|||.||....
lekGYkeffeeve
Subfamily.CDC25.PD 434-546 6e-50 159.5 In-house 2-116 (117) alignment 
Range on Protein: 434-546
Range on HMM: 2-116/117.0
KLINGDYKDEIDEYYIIDCRYPFEFDGGHVKGAINIYTKDEMLKQFIDTPKCK--EGKRVVVIFHCEFSSKRGPDMCRFLRNRDRDIHRPSYPSLFYPEL
.|..|..|..|..|.|||||||.|..|||.|||.|.|...|. ..|...||.|  | ||..|||||||||.|||...|.||..||.... .||.|.||||
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

YLLDGGYKNFFNTCK
|||.||||.||....
ylLegGykeffeeve
Family.CDC25.PD 434-546 6e-50 159.5 In-house 2-116 (117) alignment 
Range on Protein: 434-546
Range on HMM: 2-116/117.0
KLINGDYKDEIDEYYIIDCRYPFEFDGGHVKGAINIYTKDEMLKQFIDTPKCK--EGKRVVVIFHCEFSSKRGPDMCRFLRNRDRDIHRPSYPSLFYPEL
.|..|..|..|..|.|||||||.|..|||.|||.|.|...|. ..|...||.|  | ||..|||||||||.|||...|.||..||.... .||.|.||||
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

YLLDGGYKNFFNTCK
|||.||||.||....
ylLegGykeffeeve
Group.Cx5R-II.PD 434-546 6e-50 159.5 In-house 2-116 (117) alignment 
Range on Protein: 434-546
Range on HMM: 2-116/117.0
KLINGDYKDEIDEYYIIDCRYPFEFDGGHVKGAINIYTKDEMLKQFIDTPKCK--EGKRVVVIFHCEFSSKRGPDMCRFLRNRDRDIHRPSYPSLFYPEL
.|..|..|..|..|.|||||||.|..|||.|||.|.|...|. ..|...||.|  | ||..|||||||||.|||...|.||..||.... .||.|.||||
allkgetkeliekyiiiDcRypyeyegGHikgavnlysreeleeeflkepkvkaseekrtivifhCefSseRgPklarllrevdrelnkeeypkleypel

YLLDGGYKNFFNTCK
|||.||||.||....
ylLegGykeffeeve
Rhodanese Rhodanese-like domain 439-542 8.5e-14 44.0 Pfam-A 4-111 (113) alignment 
Range on Protein: 439-542
Range on HMM: 4-111/113.0
DYKDEI--DEYYIIDCRYPFEFDGGHVKGAINIYT----------KDEMLKQFIDTPKCKEGKRVVVIFHCeFSSKRGPDMCRFLRNR-DRDIhrpSYPs
. |. .  ... ..|.| | |...||..||.|.             .. |.. . . . | .|   |...| .|..|.  ....|.    . .   .|. 
elkellekekvvllDvRspeeyakghIpgAvnvpldslyprrdlffkdklaeeleesgkkldkdktvvvyc.rsgnrsggaaalllalilkel...gyk.

lfypELYLLDGGYKNFF
    . |.||||.... 
....nvyvLdGGfeawk
subfamily_Acr2_pd Subfamily Acr2 446-515 1e-06 19.2 In-house 12-89 (113) alignment 
Range on Protein: 446-515
Range on HMM: 12-89/113.0
EYYIIDCRYPfEFDGGHVKGAINI-----YTKDEMLKQFIDT--PKCKEGK-RVVVIFHCEFSSKRGPDMC-RFLRNRD
.. ..| |   .. ..|.| |  .      .. | |....     |  ...  . |||||  | .||| .   .||. |
dfqvvdvrre.dyardhikdawhvavsrlkqdkeylrelkkrllekqadsrgalkvifhctlskqrGPkvamlllrsld
M-inducer_phosp M-phase inducer phosphatase 239-279 1.1e-06 16.5 Pfam-A 135-175 (259) alignment 
Range on Protein: 239-279
Range on HMM: 135-175/259.0
DDVEAGDDGFIDDLVNSQEEKDMNMPQGMANLLSAPLVSSN
 . .  ||||.| |   . . ... | |||.|||||||  .
ktdkeeDDGFvDlldaeelkdeleepsgmasLlsaPLvkkl