Gene NEM1 in Saccharomyces cerevisiae

Synonym: YHR004C, NEM1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily DULLARD
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP030_AA protein Get Run
ScerP030_AA_249-411 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DULLARD_pd Subfamily DULLARD 251-412 2.7e-65 210.8 In-house 1-152 (153) alignment
Range on Protein: 251-412
Range on HMM: 1-152/153.0
KKKLVIDLDETLIHSASRSTTHSNSSQGHLVE--VKFGLSGIRTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSfPSSFSKRYYRS
.|.||.||||||||||..|.|.|....|. ..  ||. ......|....|||..||||..|||||||.||||||.|||..|.|.|.|. ......||||.
rktlvlDlDetlihsahdsvtkstvkpgtapdfvvkvlidkepvlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsg.rgilkrryyrq

DCVLRDGvGYIKDLSIVkdseengkgsSSSLDDVIIIDNSPVSYAMNVDNAIQVEGWISDPTDT
.|||..|  |.||||.|          ||.|..|||.|||||.|..|.||||....|.|||.||
hCvlesg.kytkdlslv..........ssdlssviilDnspvayrknpdnaipikswlsdpsdt

NIF NLI interacting factor-like phosphatase 252-431 4.1e-55 178.0 Pfam-A 1-159 (159) alignment
Range on Protein: 252-431
Range on HMM: 1-159/159.0
KKLVIDLDETLIHSASRSTThsnSSQGHLVevkfglSgIRTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSfPSSFSKRYYRSDCV
| ||.||||||.|| .....   ...|. |      . ..| ....|||..| ||...||.|...|||||.||||.||.|.|. .    |.||.||..|.
ktLVLDLDetLvhskekkdl...kedgkkv......e.ektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpk.kklfkkrlyresct

LRDGvGYIKDLSIVkdseengkgsSSSLDDVIIIDNSPVSYAMNVDNAIQVEGWISD-PTDTDLLNLLPFLEAMRYSTDVR
||.|  |.||||..          ...|..|.|.|.|| |.... ||.|..| ...| ..||.||.|||||||...|.|||
lrng.kyvKdLsll..........grdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpflealeksddvr

CPDc_SM00577 250-411 4.2e-45 145.3 In-house 1-145 (146) alignment
Range on Protein: 250-411
Range on HMM: 1-145/146.0
KKKKLVIDLDETLIHS---ASRSTTHSNSSQGHLVEvkfglsgirTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSFpSSFSKRYY
||| ||.||||||.||   |........|.. .|.|         ||....||||.|.||.|..|...|.|||...|.|||...|.|...    .....|
kkkvLVlDLdetLvhsanmaepksfsevsptdslae.........tlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkr.llkyrvly

RSDCVLRDGVgYIKD-LSIVKDseengkgsssSLDDVIIIDNSPVSYAMNVDNAIQVEGWISDPTD
|.||.| .|  ..|| ||..|           .|..|.|||||. |...| .||.... .||...|
Rqdcrlvkgk.llkddlsllkv..........dlskvviiDnseestlvnpenalkikpyisalsd

subfamily_SCP_pd Subfamily SCP 253-412 7.2e-33 105.3 In-house 2-142 (142) alignment
Range on Protein: 253-412
Range on HMM: 2-142/142.0
KLVIDLDETLIHSASRSTThsnsSQGHLVEVKfgLSGIRTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSfpSSFSKRYYRSDCVL
 |||||||||.||. .  .    .   .| |.  . |.    .. |||. | || .|.. .....||||.  ||||| | |. .  . ...| .|  || 
clvidldetlvhssfkpvk....nadfvvpve..idgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlldkk..kvlrarlfrescvf

RDGvGYIKDLSIVkdseenGKgsssSLDDVIIIDNSPVSYAMNVDNAIQVEGWISDPTDT
  |  |.|||| .      |.    .|..|||.|||| || .  .||. || |..|..||
hkg.nyvkdlsrl......gr....dlkkviivdnspasyifhpenavpveswfddkedt

subfamily_CTDSPL2_pd Subfamily CTDSPL2 254-411 1.3e-30 98.3 In-house 2-141 (142) alignment
Range on Protein: 254-411
Range on HMM: 2-141/142.0
LVIDLDETLIHSASRSTTHSNSSQghlvEVKFglSGIRTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSfPSSFSKRYYRSDCVLR
||.||||||.|.. .   ... ..    .|.|  . .    ....||.   || .||| ...|.|||| | ||| ..|.|. .    . .| .| .||  
lvldldetlvhcslekleeatltf....pvlf..enktyqvyvrlrpflreflervsklfevilftaskkvyadklldlldpe.kklikhrlfrehcvcv

DGvGYIKDLSIVkdseenGKgsssSLDDVIIIDNSPVSYAMNVDNAIQVEGWISDPTD
||  |||||||.      |.     |. .||.|||| ..|....| | .| | .| .|
dg.nyikdlsil......Gr....dlektiivdnspqafayqlenGipieswfedend

subfamily_FCP1_pd Subfamily FCP1 253-403 3.4e-17 54.9 In-house 3-140 (146) alignment
Range on Protein: 253-403
Range on HMM: 3-140/146.0
KLVIDLDETLIHSASRSTTHSNSSQGHLVEvKFGLSGIRTLYFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESSfPSSFSKRYYRSDCVL
 ||.|||.||||... .| ...... . .. || |.  .. |....||..  ||.|.|| |.| |.| . ..||. .   |. .  . ||.|    | .|
vLvvDlDqtlihttkdptievkeekkkdik.kftlpeekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpe.kklfserilsrdell

rDGVGYIKDLSIVKDSEEngkgsssslDDVIIIDNSPVSYaMNVDNAIQVE
 |    .|.|... ....         . |.|||.    . .  .| |.|.
.dassktkklkklfptdd.........smvviiDDredvW.nfaenlikvk

subfamily_TIM50_pd Subfamily TIM50 294-411 6.4e-14 44.2 In-house 21-125 (126) alignment
Range on Protein: 294-411
Range on HMM: 21-125/126.0
YFIHKRPYCDLFLTKVSKWYDLIIFTASMKEYADPVIDWLESsfPSSFSKRYYRSDCVLRDGVgYIKDLSIVKdseengkgssSSLDDVIIIDNSPVSYA
.  .|||  | || .... .....||..   .| |.|| |.    .  . | .|  . . ||   .|||| .            .|. ||..|  . |. 
wrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldP..kqlimyrlfrdatkyvdGe.hvkdlskln..........rdlskvivvdldkksvk

MNVDNAIQVEGWISDPTD
.. .||.... |  .  |
lqpenalalkkweGnadd