Gene TIM50 in Saccharomyces cerevisiae

Synonym: YPL063W, TIM50

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family FCP
Subfamily TIM50
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP072_AA protein Get Run
ScerP072_AA_190-318 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_TIM50_pd Subfamily TIM50 193-319 1.1e-57 185.6 In-house 1-126 (126) alignment 
Range on Protein: 193-319
Range on HMM: 1-126/126.0
TLVITLEDFLVHSEWSQKHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPiHAFVSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIII
|||..|.|.|||.||..|.|||..|||| |.|| .|....|||.|.|...... .. .|||| .....|.||.... |.|| |.||||||||||||||..
tlvlelkdvlvhpewtyktGwrfkkrPgvdafleqlaelfeivvftseqgltaaplidkldP.kqlimyrlfrdatkyvdGehvkdlsklnrdlskvivv

DTDPNSYKLQPENAIPMEPWNGEADDK
|.|..|.|||||||. ...|.|.||||
dldkksvklqpenalalkkweGnaddk
NIF NLI interacting factor-like phosphatase 192-339 1.5e-45 146.9 Pfam-A 1-159 (159) alignment 
Range on Protein: 192-339
Range on HMM: 1-159/159.0
LTLVITLEDFLVHSEWSQ-----------KHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLS
.|||. |.. ||||....           |. ....||||.|.|| .||..||.|.|..  ..| ... .|||| . .....|..|.|....| ..||||
ktLVLDLDetLvhskekkdlkedgkkveektkasvkkRPgldeFLkelskayevviftasskeyaepvldkldpkkklfkkrlyresctlrngkyvKdLs

KLNRDLSKVIIIDTDPNSYKLQPENAIPMEPWNGE--ADDKLVRLIPFLEYLAtQQtKDVR
.|.||||.|.|.| .|.|..|||.|.||.||..|.   |..| .|.||||.|. .. .|||
llgrdlsrvvivDdsprsfelqpdngipiepfygdsdkdtellkllpfleale.ks.ddvr
CPDc_SM00577 191-318 8.8e-36 115.1 In-house 2-145 (146) alignment 
Range on Protein: 191-318
Range on HMM: 2-145/146.0
PLTLVITLEDFLVHS----------EWSQK-----HGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHaFVSYN-LFKEHCVYKDGV
 ..||. |.. ||||          |.|..     . ... |||..|.|| ......|.|.|.|. ..|.|.|.. ||| .  ..|. |....|....| 
kkvLVlDLdetLvhsanmaepksfsevsptdslaetlvlvlkRPyvdeFLkkaaklfelvifTsaskkyadtildllDpkr.llkyrvlyRqdcrlvkgk

HIKD-LSKLNRDLSKVIIIDTDPNSYKLQPENAIPMEPWNGEADD
..|| || |..|||||.|||....|....||||....|.. . .|
llkddlsllkvdlskvviiDnseestlvnpenalkikpyisalsd
subfamily_SCP_pd Subfamily SCP 199-318 1.3e-30 98.1 In-house 22-141 (142) alignment 
Range on Protein: 199-318
Range on HMM: 22-141/142.0
EDFLVHSEWS-QKHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFvSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIIIDTDPN
 ||.|  |   ..|     |||  | ||  ... .|.|||..    |.| .|. ||  ... .. ||.|.||.. | ..||||.| |||.||||.|  |.
adfvvpveidgtvhqvyvlkrphvdeflkrvgelfevvlftaslakyadpvadlldkkkvl.rarlfrescvfhkgnyvkdlsrlgrdlkkviivdnspa

SYKLQPENAIPMEPWNGEADD
|| . ||||.|.| |  ...|
syifhpenavpveswfddked
subfamily_DULLARD_pd Subfamily DULLARD 211-318 5.7e-29 92.8 In-house 44-151 (153) alignment 
Range on Protein: 211-318
Range on HMM: 44-151/153.0
HGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIIIDTDPNSYKLQPENAIPME
  ..  |||  |.||   |..|..|.| .   .|......|||  .. ..  ....||| ..| ..|||| .. |||.|||.|  |..|. .|.||||..
vlfyvykrPhvDlfLdvvskWydlviftasmeeyaaavvdkLdsgrgilkrryyrqhCvlesgkytkdlslvssdlssviilDnspvayrknpdnaipik

PWNGEADD
 |  . .|
swlsdpsd
subfamily_CTDSPL2_pd Subfamily CTDSPL2 216-318 1.8e-28 91.3 In-house 39-141 (142) alignment 
Range on Protein: 216-318
Range on HMM: 39-141/142.0
AKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIIIDTDPNSYKLQPENAIPMEPWNGE
 .|| .  ||  .|. .|..||..   .|.||. . ||| . .. . ||.||||. || .||||| | |||.|.||.|  |... .| || ||.| |  .
rlrpflreflervsklfevilftaskkvyadklldlldpekklikhrlfrehcvcvdgnyikdlsilGrdlektiivdnspqafayqlenGipieswfed

ADD
 .|
end
subfamily_FCP1_pd Subfamily FCP1 209-312 1.4e-10 33.4 In-house 39-142 (146) alignment 
Range on Protein: 209-312
Range on HMM: 39-142/146.0
QKHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKL-NRDLSKVIIIDTDPNSYKLQPeNAI
.|. . . .||..  ||  ||..||. ... .  .| ..||. ||| . . |  ..    . .   ..|.|.|| ..| | |.|||   . .. .. | |
ekevyyvklRpnlkefleklsklyelhiytmgtraYaeqiakilDpekklfserilsrdelldassktkklkklfptddsmvviiDDredvWnfae.nli

PMEPW
 ..|.
kvkpy