Gene SSU72 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC2
Superfamily CC2
Family SSU72
Subfamily SSU72
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP123_AA protein Get Run
SpurP123_AA_0-191 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_SSU72_pd Subfamily SSU72 3-191 1.1e-100 324.2 In-house 1-189 (189) alignment 
Range on Protein: 3-191
Range on HMM: 1-189/189.0
LRIAVVCSSNQNRSMEAHAILSKKGFNVKSYGTGATVKLPGPAQDKPNIYDFKTTYEEMYQDLKRKDRDLYTQNGILHMLDRNRRIKSKPERFQNSKDKF
||||||||||||||.|||..|.||||||||||||..||||||..||||.|.|.||||..|.|||.||..||||||.|.|||||||||..|||||..|.||
lriavvcssnqnrsleahkllkkkGfnvksyGtgsavklPGpsidkPnvyefgttyediykdlkekdkelytqnGllemldrnrrikkaPerfqeekkkf

DVVLTAEERVYDQVLEDFESKEEETQIPVHIINIDIQDNHEEATIGAFRMSNLCIKLEALRDLDKEIDELIQLFEEELNISVLHTLCFY
|.|||.||||||.|.||.||.||... |||.||.||.||.||||.|||....|. .||. .||..||||... |||. . ..||.|.||
divltveervydavvedlesreeksskpvhvinvdikdnaeeatlGaflilelaeileksedledeideileefeektkrellhalafy
Ssu72 Ssu72-like protein 2-191 8.9e-85 272.4 Pfam-A 2-196 (196) alignment 
Range on Protein: 2-191
Range on HMM: 2-196/196.0
PLRIAVVCSSNQNRSMEAHAILSKKGFNVKSYGTGATVKLPGPAQDKPNIYDFKTTYEEMYQDLKRKDRDLYTQNGILHMLDRNRRIKSKPERFQNSKDK
 |..||||.|||||||||| .|...||.|||.|||..||||||. ||||.|.|.|||||.|.||..||..||..||.|.||.|||.||..|||||..|..
klklavvCasnqnRsmeaHkvlkeagfdvksfGtgsavklPGpsidkPnvyeFgttYeeiykdleskdeelYeenGllkmlernrkikkaPerfqeekea

--FDVVLTAEERVYDQVLEDFESKEEETQIPVHIINIDIQDNHEEATIGAFRMSNLCIKLE--ALRDLDKEIDELIQLFEEEL-NISVLHTLCFY
  ||||.| ||||.|.|.||....|.|.. |||.||.||.||||||..||... .|. .||  | .||..|..|... |||.  . ..|.|..||
gkfdvvitceervfdavvedllereselnrpvhvinvdikDnheealvgakailelvealeeeaeedleeeveeilaefeekepklkllytvafy
Ssu72 Ssu72-like protein 2-191 8.9e-85 272.4 In-house 2-196 (196) alignment 
Range on Protein: 2-191
Range on HMM: 2-196/196.0
PLRIAVVCSSNQNRSMEAHAILSKKGFNVKSYGTGATVKLPGPAQDKPNIYDFKTTYEEMYQDLKRKDRDLYTQNGILHMLDRNRRIKSKPERFQNSKDK
 |..||||.|||||||||| .|...||.|||.|||..||||||. ||||.|.|.|||||.|.||..||..||..||.|.||.|||.||..|||||..|..
klklavvCasnqnRsmeaHkvlkeagfdvksfGtgsavklPGpsidkPnvyeFgttYeeiykdleskdeelYeenGllkmlernrkikkaPerfqeekea

--FDVVLTAEERVYDQVLEDFESKEEETQIPVHIINIDIQDNHEEATIGAFRMSNLCIKLE--ALRDLDKEIDELIQLFEEEL-NISVLHTLCFY
  ||||.| ||||.|.|.||....|.|.. |||.||.||.||||||..||... .|. .||  | .||..|..|... |||.  . ..|.|..||
gkfdvvitceervfdavvedllereselnrpvhvinvdikDnheealvgakailelvealeeeaeedleeeveeilaefeekepklkllytvafy
LMWPc_SSU72 3-168 1.1e-44 142.6 In-house 1-130 (137) alignment 
Range on Protein: 3-168
Range on HMM: 1-130/137.0
LRIAVVCSSNQNRSMEAHAILSKK--GFNVKSYGTGATVklPGPAQDKPniydfkttyeemyqdlkrkDRDLYTQNGIlhmldrnrRIKSKPERFQNS-K
|....||.||.||||||.|.|...  |..|||.|||. |  |||. |||                   ...||..||.        .|| .||..|..  
lkvlfVCasNinRSmeAeallkealeglevkSaGtgslv..pgpsidkp...................aeelykenGl........sikeapeklqeeel

DKFDVVLTAEERVYDQVLEDFESKeEETQIPVHIINIDIQDNHEEATIGAFRMSNLCIKlealrdldkE
.|||.|.| ||||.|.|.||.... .|.. .||.||.||.|.||||..|. .. .|. .         .
ekfDlvitleervfdavvedlper.selkrkvhvinvdikDpheeaiegfkaildliee.........r
LMWPc_SSU72_ArsC 4-156 4.8e-35 111.2 In-house 2-126 (126) alignment 
Range on Protein: 4-156
Range on HMM: 2-126/126.0
RIAVVCSSNQNRSMEAHAILSKK---GFNVKSYGTGATVklPGPAQDkpniydfkttyeemyqdlkRKDRDLYTQNGIlhmldrnrRIKSKPERFQNS-K
....||..|..||..|.|.|.|.   |.||.|.|||| |  ||.  |                   .... |...|||        ..| ||...|..  
kvlfvClgNicRSpmAeavlkkavkkglnvsSaGtgaav..pgksid...................sravellkengi........elkhkprqlqeedl

DKFDVVLTAEERVYDQVLEDFESKeeeTQIPVHIINIDIQDNHEEATIGAFRMSNLC
..||..|| .||..|.|||.....   .. .||..|.|..|..|.|. |. .. .|.
kefdliltmdernkdevlellper...atkkvhllnldvkDpyegaesgfeevldli
0048765 Phosphotyrosine protein phosphatases I 1-37 2.9e-07 21.2 In-house 1-45 (154) alignment 
Range on Protein: 1-37
Range on HMM: 1-45/154.0
MPLRIAVVCSSNQNRSMEAHAILSKKG--------FNVKSYGTGA
|. .. .||  |  ||  | |.| .          . | | ||.|
mmkkvLfvCtgNicRSpmAeallrhlleeaglgdrvevdSaGtsa
0053360 Phosphotyrosine protein phosphatases I 1-38 3.3e-07 21.0 In-house 4-49 (157) alignment 
Range on Protein: 1-38
Range on HMM: 4-49/157.0
MPLRIAVVCSSNQNRSMEAHAILSKKG--------FNVKSYGTGAT
..... .||  |  ||  | |.| ..         | | | ||.| 
kmkkvLfvCtgNicRSpmAeallrhlleeaglgdrfevdSaGtsal
0046251 Phosphotyrosine protein phosphatases I 1-38 1.6e-06 18.9 In-house 4-50 (159) alignment 
Range on Protein: 1-38
Range on HMM: 4-50/159.0
MPLRIAVVCSSNQNRSMEAHAILSKKG---------FNVKSYGTGAT
|.... .||  |  ||  | |.| ..          ..| | ||.| 
mkkkvlfvCtgNicRSpmAeallrhlledaglsdllievdSaGtsal
0047572 Phosphotyrosine protein phosphatases I 1-42 6.5e-06 16.6 In-house 1-40 (130) alignment 
Range on Protein: 1-42
Range on HMM: 1-40/130.0
MPLRIAVVCSSNQNRSMEAHAILSKKG---FNVKSYGTGatvklP
.. .. .||  |  ||. | |.| . .   ..| | ||.     .
kkkkvlfvCtgNscRSpmAeallrhllgdrvevySAGte.....g
0042188 Phosphotyrosine protein phosphatases I 1-37 8.1e-06 16.5 In-house 3-42 (146) alignment 
Range on Protein: 1-37
Range on HMM: 3-42/146.0
MPLRIAVVCSSNQNRSMEAHAILSKKG---FNVKSYGTGA
..... .||  |  ||  | |.| .     . | | ||.|
kkkkvlfvCtgNicRSpmAeallrhllgdrvevdSAGtsa