Gene EYA-2 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family EYA
Subfamily EYA
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP126_AA protein Get Run
SpurP126_AA_330-600 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_EYA_pd Subfamily EYA 332-601 4.5e-159 517.6 In-house 1-270 (270) alignment 
Range on Protein: 332-601
Range on HMM: 1-270/270.0
RVFVWDLDETIIIFHSLLTGSYATRFGKDAPAAVSLGLRMEEMIFNLADMHLFFNDLEECDQVHIDDVASDDNGQDLSNYNFQTDGFHAAATSANLCLAT
|||.||||||||||.|||||||||...|||...|.|||||||.||||||..||||||||.||||.|||.|||||||||.|||.||||||||||||||||.
rvfiWdldetiiifrslltgsyatkyakdansvvalglrmeelifnladtklffndleeidqvhvddvssddngqdlstynfatdgfhaaatsanlclai

GVRGGVDWMRKLAYRYRRIKEIYSSYKNNVGGLLGPQKREQWLQLRAEIEAMTDSWLTIALKSLSIIHSRSNCINVLVTTTQLVPAVAKVLLYGLGGVFN
|||||||.|||||.|||..||.|.||||||||||||.|||.||||||||||.||||||.||||||.|.|||||.||||||||||||.|||||||||.||.
gvrgGvdvmrklafryrkvkelynsyknnvggllgpakreawlqlraeiealtdsWltlalkslslissrsncvnvlvtttqlvpalakvllyglgsvfp

IENVYSATRVGKESCFERIVARFGRKVTYVAIGDAKDEETAAKQLDFPFWRVTSHSDLAALHHALDLGYL
|||.||||..||||.|||||.|||.|||||.|||.||||||||.|..||||..||||||||..||||.||
ieniysatkiGkesvferivsrfGkkvtyvvigdgkdeetaakklnlPfWrisshsdlaalysaldleyl
EYA 331-600 7.1e-114 369.4 In-house 2-273 (274) alignment 
Range on Protein: 331-600
Range on HMM: 2-273/274.0
ERVFVWDLDETIIIFHSLLTGSYATRFG--KDAPAAVSLGLRMEEMIFNLADMHLFFNDLEECDQVHIDDVASDDNGQDLSNYNFQTDGFHAAATSANLc
|||.|||||||.|...|||.|||| .|.  ||   .|  |.|.|..|..||| |.|....||||.|..|||..||.|.|||.|.|.||||..|. . |  
ervyvWdldetlillkslldGsyaekfdglkdhkksveigkrleklileladehffyeeieecdevflddvkedddGkdlsayefetdgfstasddlnk.

latgvrggvdwmRKLAYRYRRIKEIYSSYknnVGGLLGPQKREQWLQLRAEIEAMTDSWLTIALKS---------------LSIIHSRSNCINVLVTTTQ
            ||||||||..||.| ..   ...||...|.| . .||.||. .|||||. |||.               |. |.||.|..|||||..|
............rklayryrkvkekyekg...leklldsekkealdelrseidkltdsWlssalklrlkkvcvreeadgkslleissrensvnvlvtsgq

LVPAVAKVLLYGLGGVFNIENVYSATRVGKESCFERIVARFGR-KVTYVAIGDAKDEETAAKQLDFPFWRVTSHSDLAALHHALDLGY
|.||.||||||.|.....|||||||. |||..||.||. ||.. ||..|.||| ..||||||.|..||.... |.||.|...||.|..
liPalakvllyrldeilaienvysaikvGklqcfkrikerfdkpkvrfvviGdGreeetaakalklPfvkielhpdlsarfpalelkt
CobU Cobinamide kinase / cobinamide phosphate guanyltransferase 538-574 6.2e-06 13.1 Pfam-A 6-42 (167) alignment 
Range on Protein: 538-574
Range on HMM: 6-42/167.0
ATRVGKESCFERIVARFGRKVTYVAIGDAKDEETAAK
..| || .. |...|. |.||.|.| . |.||| |..
garSGKSefAeklaaesgkkvvYiAtaeafDeemaeR