Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_DULLARD_pd | Subfamily DULLARD | 1-40 | 4.5e-16 | 50.9 | In-house | 97-136 (153) | alignment | ||
Range on Protein: 1-40
Range on HMM: 97-136/153.0
FLQHCTLDSGSYTKDLSAVHPDLSSIFIVDNSPGAYRLFP
. |||.|.||.||||||.|..||||..|.|||| ||| .|
yrqhCvlesgkytkdlslvssdlssviilDnspvayrknp
|
|||||||||
subfamily_SCP_pd | Subfamily SCP | 1-39 | 1.3e-09 | 29.9 | In-house | 87-125 (142) | alignment | ||
Range on Protein: 1-39
Range on HMM: 87-125/142.0
FLQHCTLDSGSYTKDLSAVHPDLSSIFIVDNSPGAYRLF
| ..|. |.| |||| . ||... |||||| .| .
frescvfhkgnyvkdlsrlgrdlkkviivdnspasyifh
|
|||||||||
NIF | NLI interacting factor-like phosphatase | 3-39 | 1.2e-08 | 27.0 | Pfam-A | 86-122 (159) | alignment | ||
Range on Protein: 3-39
Range on HMM: 86-122/159.0
QHCTLDSGSYTKDLSAVHPDLSSIFIVDNSPGAYRLF
..||| |.|.|||| .. |||.. |||.|| ...|
esctlrngkyvKdLsllgrdlsrvvivDdsprsfelq
|
|||||||||
subfamily_CTDSPL2_pd | Subfamily CTDSPL2 | 1-37 | 6.3e-08 | 24.7 | In-house | 87-123 (142) | alignment | ||
Range on Protein: 1-37
Range on HMM: 87-123/142.0
FLQHCTLDSGSYTKDLSAVHPDLSSIFIVDNSPGAYR
| .|| .|.| |||| . ||. . |||||| |.
frehcvcvdgnyikdlsilGrdlektiivdnspqafa
|
|||||||||
CPDc_SM00577 | 3-39 | 8e-07 | 21.1 | In-house | 92-129 (146) | alignment | |||
Range on Protein: 3-39
Range on HMM: 92-129/146.0
QHCTLDSGSYTKD-LSAVHPDLSSIFIVDNSPGAYRLF
|.|.| .|...|| || .. |||.. |.|||. ....
qdcrlvkgkllkddlsllkvdlskvviiDnseestlvn
|