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  • Table of phosphatase disease associations, taken from our 2017 phosphatome publication <cite>Che | Gene Symbol || Entrez Gene ID || Fold || Family || Subfamily || Hamosh et al. (2005) - OMIM || Landrum et al. (2014) - ClinVar || Yip et
    14 KB (1,612 words) - 16:05, 13 April 2017
  • ...Phosphatase_Family_HP1|HP, branch1 family]]: [[Phosphatase_Subfamily_TIGAR|Subfamily TIGAR]] TIGAR has a single domain: HP1 phosphatase domain.
    2 KB (323 words) - 18:28, 20 April 2017
  • ...[[Phosphatase_Family_HP1|HP, branch1 family]]: [[Phosphatase_Subfamily_STS|Subfamily STS]] STS is protein tyrosine phosphatase involved in T-cell receptor signaling by dephosphorylating the Syk and ZAP-
    4 KB (517 words) - 20:53, 10 July 2017
  • [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HP|Fold HP]]: [[Phosphatase_Superfamil ...amily [[Phosphatase_Subfamily_ACP2|ACP2]] can function as tyrosine protein phosphatase.
    2 KB (315 words) - 21:51, 25 October 2016
  • ...ase_Family_HP2|Family HP, branch 2]] (HP2): [[Phosphatase_Subfamily_PPIP5K|Subfamily PPIP5K]] ...s two domains: N-terminal RimK/ATP-grasp kinase domain, and C-terminal HP2 phosphatase domain <cite>fridy07</cite>. The RimK is the active kinase domain <cite>fr
    2 KB (222 words) - 18:04, 12 April 2017
  • ...atase_Family_HP2|Family HP, branch 2 (HP2)]]: [[Phosphatase_Subfamily_cf60|Subfamily cf60]] Cf60 has single domain, a HP2 phosphatase domain. It also has a signal peptide cleavage site.
    1 KB (147 words) - 21:50, 25 October 2016
  • ==== Second phosphatase domains of receptor PTPs ==== ...city, and dimerization <cite>denHertog02, Barr09</cite>. Because the first phosphatase domains are active, these receptor PTPs are active at protein level. These
    6 KB (818 words) - 00:36, 14 April 2017
  • ...atase_Subfamily_CDC14|CDC14]] subfamily, where CDC14A and CDC14B have dual phosphatase domains, with the first being a pseudophosphatase. ... |STYXL1]], and a single member of the [[Phosphatase_Subfamily_DSP3|DSP3]] subfamily, DUSP27.
    5 KB (688 words) - 00:38, 14 April 2017
  • We use HMMs to detect phosphatase domains and accessory domains. We benefit from the HMMs in public database == HMMs for Determining the Boundaries of Protein Phosphatase Domain ==
    7 KB (1,042 words) - 18:26, 15 March 2017

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