Difference between revisions of "Phosphatase Family OCA"
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_CC1|Fold CC1]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]: [[Phosphatase_Family_OCA|OCA]] | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_CC1|Fold CC1]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]: [[Phosphatase_Family_OCA|OCA]] | ||
Revision as of 23:55, 26 February 2015
Phosphatase Classification: Fold CC1: Superfamily CC1: OCA
The OCA family is named after the five member genes in yeast (OCA1-5 = Oxidant-induced Cell-cycle Arrest). The family is also called plant and fungi atypical (PFA)-DSPs [1, 2].
Evolution
OCA is found in most eukaryotes other than eumetazoa. We have seen it in fungi, plants, protists, monosiga, and sponge.
Domain
OCA has a single domain, a phosphatase domain of fold CC1.
Functions
Yeast OCA members are involved in cell cycle arrest in response to oxidative damage[3], in telomere capping [4], in actin organization [5]. OCA3 has been shown to control intracellular localization of Gln3 (a phosphorylated transcriptional activator), in cooperation with Npr1 kinase [6].
References
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Error fetching PMID 17976645:
Error fetching PMID 21409566:
Error fetching PMID 18845848:
Error fetching PMID 18166280:
- Error fetching PMID 17976645:
- Error fetching PMID 21409566:
- Error fetching PMID 11408586:
- Error fetching PMID 18845848:
- Error fetching PMID 15020461:
- Error fetching PMID 18166280:
