Difference between revisions of "Phosphatase Family Paladin"

Latest revision as of 23:46, 31 January 2016

The Paladin family consists of one subfamily Paladin.

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 [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_CC1|Fold CC1]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]:  [[Phosphatase_Family_Paladin|Family Paladin]]
-The phosphatase family Paladin has one [[Phosphatase_Subamily_Paladin|subfamily Paladin]].
+The Paladin family consists of one [[Phosphatase_Subamily_Paladin|subfamily Paladin]].
-=== Evolution ===
-Paladins are found in vertebrates and early metazoa such as sponge, trichoplax and nematostella but absent from arthropoda and nematoda. Paladins are also found in most plants and a small number of fungi (see internal database [http://resdev.gene.com/gOrtholog/view/cluster/MC0005718/overview gOrtholog]).
-=== Domain ===
-The Paladin subfamily has a single domain, which lacks the cysteine residue at Cx5R catalytic motif common among CC1-fold phosphatases.
-=== Function ===
-Little is known about Paladin's molecular function. It regulates phosphorylation status in neural crest cell formation and migration in chicken <cite>Roffers-Agarwal12</cite>, but it lacks the residue necessary for phosphatase activity.
-Human Paladin is widely expressed in different tissues according to [http://www.gtexportal.org/home/gene/PALD1 GTEx].
-=== References ===
-<biblio>
-#Roffers-Agarwal12 pmid=22926139
-</biblio>