Difference between revisions of "Phosphatase Subfamily PXYLP1"
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| − | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HP|Fold HP]]: [[Phosphatase_Superfamily_HP|Superfamily HP]] | + | __NOTOC__ |
| + | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HP|Fold HP]]: [[Phosphatase_Superfamily_HP|Superfamily HP]]: [[Phosphatase_Family_HP2|Family HP, branch 2]]: [[Phosphatase_Subfamily_PXYLP1|Subfamily PXYLP1]] | ||
=== Evolution === | === Evolution === | ||
| − | + | PXYLP1 is found in bilateria. | |
=== Domain === | === Domain === | ||
| − | + | PXYLP1 has a N-terminal transmembrane region and C-terminal phosphatase domain. | |
=== Functions === | === Functions === | ||
| + | [http://www.ncbi.nlm.nih.gov/gene/?term=92370 Human PXYLP1] dephosphorylates [http://en.wikipedia.org/wiki/Xylose xylose], a sugar, in the glycosaminoglycan-protein linkage region of proteoglycans . In collaboration with kinase [http://kinase.com/wiki/index.php/FAM20B FAM20B], it regulates the transient phosphorylation of the Xyl residue in the glycosaminoglycan-protein linkage region, which controls the formation of glycosaminoglycan chains of proteoglycans <cite>koike14</cite>. | ||
| + | === Related kinase === | ||
| + | [http://kinase.com/wiki/index.php/FAM20B FAM20B]. | ||
=== References === | === References === | ||
| + | <biblio> | ||
| + | #koike14 pmid=24425863 | ||
| + | </biblio> | ||
Latest revision as of 22:55, 25 October 2016
Phosphatase Classification: Fold HP: Superfamily HP: Family HP, branch 2: Subfamily PXYLP1
Evolution
PXYLP1 is found in bilateria.
Domain
PXYLP1 has a N-terminal transmembrane region and C-terminal phosphatase domain.
Functions
Human PXYLP1 dephosphorylates xylose, a sugar, in the glycosaminoglycan-protein linkage region of proteoglycans . In collaboration with kinase FAM20B, it regulates the transient phosphorylation of the Xyl residue in the glycosaminoglycan-protein linkage region, which controls the formation of glycosaminoglycan chains of proteoglycans [1].
