Difference between revisions of "Phosphatase Subfamily PXYLP1"
From PhosphataseWiki
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| − | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HP|Fold HP]]: [[Phosphatase_Superfamily_HP|Superfamily HP]] (histidine phosphatase): [[Phosphatase_Family_HP2|Family HP, branch 2]]: [[Phosphatase_Subfamily_PXYLP1|PXYLP1]] | + | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HP|Fold HP]]: [[Phosphatase_Superfamily_HP|Superfamily HP]] (histidine phosphatase): [[Phosphatase_Family_HP2|Family HP, branch 2]]: [[Phosphatase_Subfamily_PXYLP1|Subfamily PXYLP1]] |
=== Evolution === | === Evolution === | ||
Revision as of 21:54, 1 January 2015
Phosphatase Classification: Fold HP: Superfamily HP (histidine phosphatase): Family HP, branch 2: Subfamily PXYLP1
Contents
Evolution
PXYLP1 is found in bilateria, but Entamoeba histolytica and Emiliania huxleyi have PXYLP1 like genes.
Domain
PXYLP1 has a N-terminal transmembrane region and C-terminal phosphatase domain.
Functions
Human PXYLP1 dephosphorylates xylose, a sugar, in the glycosaminoglycan-protein linkage region of proteoglycans . In collaboration with kinase FAM20B, it regulates the transient phosphorylation of the Xyl residue in the glycosaminoglycan-protein linkage region, which controls the formation of glycosaminoglycan chains of proteoglycans [1].
