Difference between revisions of "Phosphatase Subfamily MINPP1"
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=== Evolution === | === Evolution === | ||
| − | MINPP1 is found broadly in eukaryotes but absent from many genomes, such as ''C elegans''. | + | MINPP1 is found broadly in eukaryotes but absent from many genomes, such as ''C elegans''. Human has a single copy, but yeast have as many as five copies. |
=== Domain === | === Domain === | ||
Revision as of 00:09, 2 January 2015
Phosphatase Classification: Fold HP: Superfamily HP (histidine phosphatase): Family HP, branch 2: MINPP1
Contents
Evolution
MINPP1 is found broadly in eukaryotes but absent from many genomes, such as C elegans. Human has a single copy, but yeast have as many as five copies.
Domain
MINPP1 has phosphatase domain and N-terminal signal peptide cleavage site.
Functions
Human MINPP1 is the only hitherto known InsP6 phosphatase. It has been shown to be predominantly localized in the lumen of the ER (endoplasmatic reticulum) [1, 2].
References
Error fetching PMID 8384201:
Error fetching PMID 10938126:
Error fetching PMID 10938126:
- Error fetching PMID 8384201:
- Error fetching PMID 10938126:
