Difference between revisions of "Phosphatase Superfamily CC1"
From PhosphataseWiki
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| − | [[Phosphatase classification]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]] | + | [[Phosphatase classification]]: [[Phosphatase_Fold_CC1|Fold CC1]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]] |
CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human: | CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human: | ||
Revision as of 21:52, 19 February 2015
Phosphatase classification: Fold CC1: Superfamily CC1
CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human:
- Classic PTP (Protein Tyrosine Phosphatase; generally tyrosine specific)
- DSP (Dual Specificity Phosphatases; tyr/ser/thr specific)
- PTEN Lipid phosphatases closely related to DSPs.
- Myotubularin (lipid specific).
Fungi, plants and many protists also have the OCA family.
It shares a Cys-based catalytic motif, CX5R with another two superfamilies CC2 and CC3, but it has distinct structure from them.
