Difference between revisions of "Phosphatase Subfamily PTPN9"

Revision as of 16:11, 17 March 2015

Phosphatase Classification: Fold CC1:Superfamily CC1: Family PTP: Subfamily PTPN9 (MEG2/PTPMEG2)

Evolution

Domain

PTPN9 has two domains: a N-terminal domain homologous to yeast SEC14p and a C-terminal phosphatase domain [1].

Functions

PTPN9 is widely expressed in different tissues [1] (also see GTEx).

References

1. Gu M, Warshawsky I, and Majerus PW. Cloning and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2980-4. DOI:10.1073/pnas.89.7.2980 | PubMed ID:1557404 | HubMed [Gu92]