Difference between revisions of "Phosphatase Superfamily CC1"
From PhosphataseWiki
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* [[Phosphatase_Family_Myotubularin|Myotubularin]] - phosphoinositide phosphatases. | * [[Phosphatase_Family_Myotubularin|Myotubularin]] - phosphoinositide phosphatases. | ||
| − | * [[ | + | * [[Phosphatase_Family_Sac|SAC]] - phosphoinositide phosphatases. |
* [[Phosphatase_Family_Paladin|Paladin]] - catalytically inactive phosphatase. | * [[Phosphatase_Family_Paladin|Paladin]] - catalytically inactive phosphatase. | ||
Revision as of 20:57, 27 April 2015
Phosphatase classification: Fold CC1: Superfamily CC1
CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of the families in human as below:
- PTP (Protein Tyrosine Phosphatase) - generally tyrosine-specific phosphatases.
- DSP (Dual Specificity Phosphatases) - diverse substrates, from tyrosine, serine, threonine to small molecules.
- PTEN - phosphoinositide phosphatases.
- Myotubularin - phosphoinositide phosphatases.
- SAC - phosphoinositide phosphatases.
- Paladin - catalytically inactive phosphatase.
Fungi, plants and many protists also have the OCA family.
It shares a Cys-based catalytic motif, CX5R with another two superfamilies CC2 and CC3, but it has distinct structure from them.
