Difference between revisions of "Phosphatase Family PAP"
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* [[Phosphatase_Subfamily_PAPL|PAPL]]. PAPL is found in holozoa, but is lost in most arthropods. Its function is unclear. | * [[Phosphatase_Subfamily_PAPL|PAPL]]. PAPL is found in holozoa, but is lost in most arthropods. Its function is unclear. | ||
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| + | Besides, [[Phosphatase_Subfamily_DCR2|DCR2]] subfamily is present in most fungi, most plants and some chromalveolata. | ||
Revision as of 00:37, 27 May 2015
Phosphatase Classification: Fold MTDP: Superfamily MTDP: Family PAP (purple acid phosphatase)
PAP is short for purple acid phosphatase. The family is found in most eukaryotes, even in some prokaryotes. It has two subfamilies present in human:
- ACP5. ACP5 subfamily is found in most eukaryotes. Human ACP5 hydrolyzes a variety of phosphomonoesters at acid pH in vitro. It also shows phosphatase activity towards the protein osteopontin, and the mannose 6-phosphate modification on lysosomal proteins.
- PAPL. PAPL is found in holozoa, but is lost in most arthropods. Its function is unclear.
Besides, DCR2 subfamily is present in most fungi, most plants and some chromalveolata.
