Difference between revisions of "Phosphatase Subfamily MTMR3"
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Revision as of 18:57, 30 December 2014
Phosphatase Classification: FoldCC1: Superfamily CC1: Family Myotubularin: MTMR3
MTMR1 is a lipid phosphatase that dephosphorylates the second messenger phosphatidylinositol 3-monophosphate [PI(3)P].
Evolution
MTMR1 is in metazoan. It consists of two members in human, MTMR3 and MTMR4. In fruit fly and C elegans, a single copy is found.
Domain Structure
MTMR3 subfamily has a conserved domain combination: phosphatase domain and FYVE domain, which can bind to the second messenger phosphatidylinositol 3-monophosphate PI3P.
Catalytic activity and functions
Human MTMR3
Related Kinases
See PI3K.
References
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Error fetching PMID 10900271:
Error fetching PMID 12217958:
Error fetching PMID 11733541:
- Error fetching PMID 11001925:
- Error fetching PMID 10900271:
- Error fetching PMID 12217958:
- Error fetching PMID 11733541:
