Phosphatase Superfamily CC1
From PhosphataseWiki
Phosphatase classification: Fold CC1: Superfamily CC1
CC1 (or Cysteine-based, group 1) is the largest phosphatase superfamily. It consists of three families in human:
- Classic PTP (Protein Tyrosine Phosphatase; generally tyrosine specific)
- DSP (Dual Specificity Phosphatases; tyr/ser/thr specific)
- PTEN Lipid phosphatases closely related to DSPs.
- Myotubularin (lipid specific).
Fungi, plants and many protists also have the OCA family.
It shares a Cys-based catalytic motif, CX5R with another two superfamilies CC2 and CC3, but it has distinct structure from them.
