Phosphatase Subfamily PTPN5 RR

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Phosphatase Classification: Fold CC1: Superfamily CC1: Family PTP: Subfamily PTPN5

Evolution

Domain Structure

Functions

PTPN5 (STEP)

PTPN5 is also termed as "striatum enriched phosphatase" (STEP), since it is highly enriched within the striatum relative to other brain areas [1].

PTPN7 (HEPTP/LC-PTP)
PTPRR (EC-PTP/PTP-SL)

References

  1. Lombroso PJ, Murdoch G, and Lerner M. Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum. Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):7242-6. DOI:10.1073/pnas.88.16.7242 | PubMed ID:1714595 | HubMed [Lombroso91]
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