Phosphatase Subamily Paladin

Phosphatase Classification: Fold CC1: Superfamily CC1: Family Paladin: [[Phosphatase_Subamily_Paladin|subfamily Paladin]

Evolution

Paladins are found in vertebrates and early metazoa such as sponge, trichoplax and nematostella but absent from arthropoda and nematoda. Paladins are also found in most plants and a small number of fungi (see internal database gOrtholog).

Domain

The Paladin subfamily has a single domain, which lacks the cysteine residue at Cx5R catalytic motif common among CC1-fold phosphatases.

Function

Little is known about Paladin's molecular function. It regulates phosphorylation status in neural crest cell formation and migration in chicken [1], but it lacks the residue necessary for phosphatase activity.

References

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