Phosphatase Subfamily YMR1

Phosphatase Classification: Fold CC1: Superfamily CC1: Family Myotubularin: Subfamily YMR1

YMR1 encodes PI(3)P phosphatase found in fungi [1]. It is the single myotubularin in most fungi.

Evolution

YMR1 is found in most fungi.

Domain Structure

YMR1 subfamily has three domains: PH/GRAM, phosphatase domain and coiled-coil domain. The GRAM domain is similar to PH domain in structure and is found in membrane-associated proteins.

Catalytic activity and functions

YMR1 of budding yeast encodes PI(3)P phosphatase, so does its ortholog in fission yeast [1, 2].

References

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