Difference between revisions of "Phosphatase Gene DUSP3"
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_CC1|Fold CC1]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]: [[Phosphatase_Family_DSP|Family DSP]] | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_CC1|Fold CC1]]: [[Phosphatase_Superfamily_CC1|Superfamily CC1]]: [[Phosphatase_Family_DSP|Family DSP]] | ||
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| + | === Functions === | ||
| + | |||
| + | |||
| + | === Diseases === | ||
| + | DUSP3 plays a selective and essential role in collagen- and CLEC-2-mediated platelet activation and thrombus formation ''in vivo'' <cite>Musumeci14</cite>. | ||
| + | |||
| + | === References === | ||
| + | <biblio> | ||
| + | #Musumeci14 pmid=25520375 | ||
| + | </biblio | ||
Latest revision as of 19:13, 19 December 2014
Phosphatase Classification: Fold CC1: Superfamily CC1: Family DSP
Functions
Diseases
DUSP3 plays a selective and essential role in collagen- and CLEC-2-mediated platelet activation and thrombus formation in vivo [1].
References
- Musumeci L, Kuijpers MJ, Gilio K, Hego A, Théâtre E, Maurissen L, Vandereyken M, Diogo CV, Lecut C, Guilmain W, Bobkova EV, Eble JA, Dahl R, Drion P, Rascon J, Mostofi Y, Yuan H, Sergienko E, Chung TD, Thiry M, Senis Y, Moutschen M, Mustelin T, Lancellotti P, Heemskerk JW, Tautz L, Oury C, and Rahmouni S. Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis. Circulation. 2015 Feb 17;131(7):656-68. DOI:10.1161/CIRCULATIONAHA.114.010186 |
