Difference between revisions of "Phosphatase Subfamily DCR2"

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=== Evolution ===
 
=== Evolution ===
The DCR2 subfamily is found in most fungi, most plants and a few chromalveolata.
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The DCR2 subfamily is found in most fungi, most plants and a few chromalveolates.
  
 
=== Domain Structure ===
 
=== Domain Structure ===
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=== Function ===
 
=== Function ===
DCR2 dephosphorylated inositol requirement 1 (Ire1), an endoplasmic reticulum transmembrane UPR sensor in ''Saccharomyces cerevisiae'' <cite>Guo06</cite>.
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DCR2 dephosphorylates Ire1, a conserved endoplasmic reticulum transmembrane UPR sensor in ''Saccharomyces cerevisiae'' <cite>Guo06</cite>.
  
 
=== References ===
 
=== References ===

Revision as of 00:43, 9 May 2016

Phosphatase Classification: Fold MTDP:Superfamily MTDP: Family PAP: DCR2

Evolution

The DCR2 subfamily is found in most fungi, most plants and a few chromalveolates.

Domain Structure

DCR2 has a single phosphatase domain.

Function

DCR2 dephosphorylates Ire1, a conserved endoplasmic reticulum transmembrane UPR sensor in Saccharomyces cerevisiae [1].

References

  1. Guo J and Polymenis M. Dcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiae. EMBO Rep. 2006 Nov;7(11):1124-7. DOI:10.1038/sj.embor.7400813 | PubMed ID:16990850 | HubMed [Guo06]