Difference between revisions of "Phosphatase Subfamily DCR2"

From PhosphataseWiki
Jump to: navigation, search
(Created page with "Phosphatase Classification: Fold MTDP:Superfamily MTDP: Phosphatase_Family_PAP|Fami...")
 
 
(2 intermediate revisions by 2 users not shown)
Line 1: Line 1:
[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_MTDP|Fold MTDP]]:[[Phosphatase_Superfamily_MTDP|Superfamily MTDP]]: [[Phosphatase_Family_PAP|Family PAP]]: [[Phosphatase_Subfamily_DCR2|DCR2]]
+
__NOTOC__
 +
[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_PPPL|Fold PPPL]]: [[Phosphatase_Superfamily_PPPL|Superfamily PPPL]]: [[Phosphatase_Family_PAP|Family PAP]]: [[Phosphatase_Subfamily_DCR2|DCR2]]
  
 
=== Evolution ===
 
=== Evolution ===
The DCR2 subfamily is found in most fungi, most plants and a few chromalveolata.
+
The DCR2 subfamily is found in most fungi, most plants and a few chromalveolates.
  
 
=== Domain Structure ===
 
=== Domain Structure ===
Line 8: Line 9:
  
 
=== Function ===
 
=== Function ===
DCR2 dephosphorylated inositol requirement 1 (Ire1), an endoplasmic reticulum transmembrane UPR sensor in ''Saccharomyces cerevisiae'' <cite>Guo06</cite>.
+
DCR2 dephosphorylates Ire1, a conserved endoplasmic reticulum transmembrane UPR sensor in ''Saccharomyces cerevisiae'' <cite>Guo06</cite>.
  
 
=== References ===
 
=== References ===

Latest revision as of 17:25, 13 March 2017

Phosphatase Classification: Fold PPPL: Superfamily PPPL: Family PAP: DCR2

Evolution

The DCR2 subfamily is found in most fungi, most plants and a few chromalveolates.

Domain Structure

DCR2 has a single phosphatase domain.

Function

DCR2 dephosphorylates Ire1, a conserved endoplasmic reticulum transmembrane UPR sensor in Saccharomyces cerevisiae [1].

References

  1. Guo J and Polymenis M. Dcr2 targets Ire1 and downregulates the unfolded protein response in Saccharomyces cerevisiae. EMBO Rep. 2006 Nov;7(11):1124-7. DOI:10.1038/sj.embor.7400813 | PubMed ID:16990850 | HubMed [Guo06]