Gene MTMR1-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR1
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP022_AA protein Get Run
AqueP022_AA_123-193 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
GRAM GRAM domain 11-54 1.4e-10 32.0 Pfam-A 28-68 (69) alignment 
Range on Protein: 11-54
Range on HMM: 28-68/69.0
GSIEGTVYISSYKMYFKSDPTPKNTeesVVLNVPLGVITHVEKI
|  .|..|...|...|.||.. ...   ||. .||..|. |||.
gpvqGrlYlTnyrliFrSdklddsk...vvvvipladikrveks
subfamily_MTMR6_pd Subfamily MTMR6 112-193 1.8e-21 68.9 In-house 2-85 (397) alignment 
Range on Protein: 112-193
Range on HMM: 2-85/397.0
YAFHFRG----DYPDDGWEVYDPEAELKRMGVGNDgvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVIQF
|||...     .   .||. .| .||..|||| |.   | ...|||.|||||||.... || . . |.. | ..||||||.||. .
yafsykpkkdkeekvsGwklldlkaeytrmgvpne..kwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsy
subfamily_MTMR9_pd Subfamily MTMR9 119-193 8.7e-18 56.5 In-house 9-81 (393) alignment 
Range on Protein: 119-193
Range on HMM: 9-81/393.0
DYPDDGWEVYDPEAELKRMGVGNDGvpWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVIQF
.  .||.. .|.| |.... .  |.  ||| . |||...| .| ... || . .|| .. .|.||..||.||...
tiledgysafdrenefaklisasde..wRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsy
subfamily_MTMR1_pd Subfamily MTMR1 120-193 2.8e-29 94.6 In-house 2-74 (389) alignment 
Range on Protein: 120-193
Range on HMM: 2-74/389.0
YPDDGWEVYDPEAELKRMGVGNDGvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVIQF
. .|||.||||||||.|.|. |.   |||..|||.|||||||.....||...|||....||.||||||.||...
lkedGWkvydpeaelerlgllnek.lWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlsw
subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 121-193 5.7e-25 80.3 In-house 12-83 (404) alignment 
Range on Protein: 121-193
Range on HMM: 12-83/404.0
PDDGWEVYDPEAELKRMGVGNDGvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVIQF
 .||| .||.| | ||.|. ..  .||| ..|..||||.|| ... || ..||| .. ||.|||||||||. .
ledgwliydaeeEykRlgikses.eWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlsw
Myotub-related Myotubularin-like phosphatase domain 121-192 6.1e-23 74.1 Pfam-A 17-87 (353) alignment
Myotub-related Myotubularin-like phosphatase domain 121-192 6.1e-23 74.1 In-house 17-87 (353) alignment
0040695 (Phosphotyrosine protein) phosphatases II 122-193 6e-21 68.6 In-house 5-74 (388) alignment 
Range on Protein: 122-193
Range on HMM: 5-74/388.0
DDGWEVYDPEAELKRMGVGNDgvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVIQF
 .|| .||.. ||||.|.|.|  .|||...|.|||||..| . . ||  .|||... ||.|||||||||. .
eegwslydilrelkrlglgld..lwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsy
subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 123-191 6.2e-12 37.0 In-house 14-87 (405) alignment 
Range on Protein: 123-191
Range on HMM: 14-87/405.0
DGWEVYDPEAELKRMGVGND----G-VPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVI
||||||. . |  |. .  |    . . |..  .||.|..| .|.|.. |  .. |  .. .  |||||||| .
dgwevynqkkeylrfniyideenssncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripsl
subfamily_pats1_pd Subfamily pats1 123-191 9.3e-07 19.6 In-house 4-69 (691) alignment 
Range on Protein: 123-191
Range on HMM: 4-69/691.0
DGWEVYDPEAELKRMGVGNDgVPWRICHLNkNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGrIPVI
. ...| .  | .|...  |   ||. ..  . .|.. |  .  ||   |||...  .. || . |||.
eifdiyslliegqrlkldld.kdwrvvefl.srdlseiyPkrilvPklvsdellvsyvrkrssk.iPvl
subfamily_MTMR3_pd Subfamily MTMR3 130-191 7e-15 47.7 In-house 29-89 (442) alignment 
Range on Protein: 130-191
Range on HMM: 29-89/442.0
PEAELKRMGVGNDGvPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVI
 ..|..|.|   ..  ||| ..|....|| .| ... ||   .|.... ||.||| .|.|..
lkeeverlGfdlke.awrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPav
subfamily_MTMR5_pd Subfamily MTMR5 134-191 1.4e-11 35.9 In-house 14-76 (483) alignment 
Range on Protein: 134-191
Range on HMM: 14-76/483.0
LKRMGVG-----NDGVPWRICHLNKNYELCDTYTSTFSVPLNCSDEMVQGVAQFRSKGRIPVI
 ||.|.|     .  ...|| . ||.|..|..| . . || ..||. .. ||.   ..|.||.
ykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvv