Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0051429 | (Phosphotyrosine protein) phosphatases II | 11-299 | 8.7e-38 | 125.9 | In-house | 4-272 (272) | alignment | ||
Range on Protein: 11-299
Range on HMM: 4-272/272.0
ESLPNFRQAGGRgltnkrGQQVKDGLLYRSAKTDYVTAKDKSLFLQLGIKSIIDIRGEKEYRKLTSRPLDNlytptvitdnktsdltehkdtsvgrrylf
... |.| || |..||.|.||||. .||.| . .||||.|.|.|.| |. .| ..
sgyiNardvggy......grvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywp.............................
dvfskelirhignqvN-----------------IIITILAVMFLLPIDKIFGTHFFPRLYSRLVIRHQSLYQQYMDYLEYSKPV--FSGMLKLLLSheeN
. .. . ... . . ... .|.. .. . .|.|.. .. | . .|.|||. .
...............girylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld...g
LPVLIHCVYGKDRTGVLVALILDCIGVERETIAMDYASSEDGLVSMRNEMYDDLI--------------VNWGMAEHSCQAKADTMLKVLNEIDKRYGST
|||.|| ||||||..|||.| ||..|||. ||. .. .| ..|. . . . ... ...|...| .|..||..|||.
gpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvraeyllaaldaideeyGsv
SQYLESIGFTLEDQESLKSILL
.||...|.. |..| |...||
egYLrdlglseeelerLrellL
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 11-242 | 2.1e-18 | 61.8 | In-house | 3-143 (151) | alignment | ||
Range on Protein: 11-242
Range on HMM: 3-143/151.0
ESLPNFRQAGGRgltnkrgqqvkdglLYRSAKTdyvTAKDKSLFLQLGIKSIIDIRGEKEYRkLTSRPLDN---LYTPTVITDNKTSDltehkdtsvgrr
....||.. .|. ||||. .| . |. .||||.|...|.|.|. ..| . .. |.|... .
sdyinfsyvtgg..............lyrsggp...ladflellkelgiktivnlrseeerg.ycpeylpelgievlhipildwpdpg............
ylfdvfskelirhignqvniiitilavmfllpidkifgthffprlysrlvirhqslyqqymdyLEYSKPVFSGMLKLLLShEENLPVLIHCVYGKDRTGV
|. | . . .|.|||. .| |||.|| ||.|||.
...............................................................lplsfdavleflellld.kkngpvlvHCsaGkgRTGt
LVALILDCIGVERETIAMDYASSEDGLVSMRNEMY
||||.| . || |.. .| .. |.| ....
lvalylmllgvsleealeeyrlkrpgvvqpnqqfl
|
|||||||||
subfamily_OCA_pd | Subfamily OCA | 12-300 | 3.9e-163 | 531.5 | In-house | 1-278 (282) | alignment | ||
Range on Protein: 12-300
Range on HMM: 1-278/282.0
SLPNFRQAGGRGLTNKRGQQVKDGLLYRSAKTDYVTAKDKSLFLQLGIKSIIDIRGEKEYRKLTSRPLDNLYTPTVITDNKTSDLTEHKDTSVGRRYLFD
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
slpnfrqaggrgltnkrgqqvkdgllyrsaktdyvtakdkslflqlgiksiidirgekeyrkltsrpldnlytptvitdnktsdltehkdtsvgrrylfd
VFSKELIRHIGNQVNIIITILAVMFLLPIDKIFGTHFFPRLYSRLVIRHQSLYQQYMDyleysKPVFSGMLKLLLSHEENLPVLIhcvygkDRTGVLVAL
|||||||||||||||||||||||||||||||||||||||||||....|..||...|.| |||.||.|.|||..|||||.|| ||.|...||
vfskelirhignqvniiitilavmfllpidkifgthffprlyslvpprnfslveeykd.....kpvisgllrlllpeeenlpfLi......drlglktal
ILDCIGVERETIAmDY-ASSEDGLVSMRNEMYDDLIVNWGMA-EHSCQAKADTMLKVLNEiDKRYGSTSQYLESIGFTLEDQESLKSILLH
|||...||||||| |. ||||..|||.|||...||..|...| |.|||||.||.||||.. ||.|||||.|||.||||||||||||||||.
iLdaeeveretia.dflasseiklvslrnevlkdlldndnyavelscqaktdtvlkvLrk.dkkygstsiyleyigFtledqeslksilli
|
|||||||||
Y_phosphatase3 | Tyrosine phosphatase family | 15-82 | 1.1e-12 | 43.2 | Pfam-A | 1-66 (164) | alignment | ||
Range on Protein: 15-82
Range on HMM: 1-66/164.0
NFRQAGGrgLTNKRGQQVKDGLLYRSAKTDYVTAKDKSLFLQLGIKSIIDIRGEKEYRKLTSRPLDNL
||| || .... |..|. |.|||||... .|..|. . .|||| ..| | |.| .| ... ...
NfRDlGg..yptadgrtvrpgvlyRSaalsklteadlaaLaelgiktvvDLRseeEvekepdklpegv
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 31-213 | 1.9e-11 | 39.4 | In-house | 25-132 (178) | alignment | ||
Range on Protein: 31-213
Range on HMM: 25-132/178.0
QVKDGlLYRSAKTDyvtAKDKSLFLQLGIKSIIDIRGEKEYRKLTS---RPLDNLytptvitdnktsdltehkdtsvgrrylfdvfskelirhignqvni
.. .| ||... . |.|. |. .|||..|.....|.|. .| . | ..
eilpg.lylgslpp...addlellkelgithivnlteelelgflkcdpywpeeag.............................................
iitilavmfllpidkifgthffprlysrlvirHQSLYQQYMDYLEYS-KPVFSGMLKLLLSH--EENLPVLIHCVYGKDRTGVLVALIL
| |. . |. . . | ..... .. |.. |||.|| .|..|.|.|||. |
................................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaayl
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 34-213 | 1.5e-10 | 36.5 | In-house | 9-105 (144) | alignment | ||
Range on Protein: 34-213
Range on HMM: 9-105/144.0
DGlLYRSaktDYVTAKDKSLFLQLGIKSIIDIRGEKEYRKLTSRpldnlytptvitdnktsdltehkdtsvgrrylfdvfskelirhignqvniiitila
.| ||.. .. ||.| |. .|||. .|... | |. |.
pg.lylg...slptaldlellkklgittvinlteeyepeflere........................................................
vmfllpidkifgthffprlysrlVIRHQSLYQQYMDYLEYSkPVFSGMLKLLLS-HEENLPVLIHCVYGKDRTGVLVALIL
.|... | .. ... . .|... . .||. |||.|| .|..|||.|||. |
.......................giqylhlpwpDhgvpdll.ellleflefieealeeggpvlVHCsaGvgRtgtlvaayl
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 34-213 | 7.4e-10 | 34.2 | In-house | 9-103 (145) | alignment | ||
Range on Protein: 34-213
Range on HMM: 9-103/145.0
DGlLYRSaktDYVTAKDKSLFLQLGIKSIIDIrgekeyrkltsrpldnlytptvitdnktsdltehkdtsvgrrylfdvfskelirhignqvniiitila
.| ||.. .. ||.| |. .|||. ....
pg.lylg...slptaldlellkdlgittvlnl....................................................................
vmfllpidkifgtHFFPRLYSRLVIRHQSLYQQYMDYLEYSKPVFSGMLKLLLSHEENLPVLIHCVYGKDRTGVLVALIL
..|..||.|... | .. . .. . . . . ..|. |||.|| |..|||.|||. |
.............tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaayl
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 36-216 | 1.7e-10 | 36.4 | In-house | 22-125 (172) | alignment | ||
Range on Protein: 36-216
Range on HMM: 22-125/172.0
LLYRSAKTDYVTAKDKSLFLQLGIKSIIDIRGEkeyrkltsrpldnlytptvitdnktsdltehkdtsvgrrylfdvfskelirhignqvniiitilavm
.. . ... .|.. .. .|||. |... ..
fiatqgplrntladfwrmlkelgithivnltel...................................................................
fllpidkifgtHFFPRLYSRLVIRHQSLYQQYMDYLeySKPVFSGMLKLLLS---HEENLPVLIHCVYGKDRTGVLVALILDCI
| |..||.|... |. .. . .. .|... . ... |||.||..|..|||.|||. | .
...........lydpellerlgiqylylpwpDhgvp..llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylmll
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 44-218 | 9.4e-11 | 37.2 | In-house | 27-131 (174) | alignment | ||
Range on Protein: 44-218
Range on HMM: 27-131/174.0
DyvtakDKSLFLQLGIKSIIDIRGEKEYRKLTSRPLDNLytptvitdnktsdltehkdtsvgrrylfdvfskelirhignqvniiitilavmfllpidki
. . .. .|||..... . ||| . . .
a.....fwemlkelgittvvmlleekelglykcinywpe.............................................................
fgthfFPRLYSRLVIRHQSLYQQYMDYLEYSKpvFSGMLKLLLSH---EENLPVLIHCVYGKDRTGVLVALILDCIGV
.. ..||.|... | . . |. . ..|.. .. .. |||.|| |..|||.|||. | . |
.....lredlerlgiqylylpwpDhgvpdlsi..llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgl
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 46-220 | 1.3e-09 | 33.5 | In-house | 66-214 (249) | alignment | ||
Range on Protein: 46-220
Range on HMM: 66-214/249.0
VTAKDKSLFLQLGIKSIIDIRGEKEYRKLTsrpldnlytptvitdnktsdltehkdtsvgrrylfdvfS-------------------------------
.... .. .|||..|.... ..|. . .
tvedfwrmlwelgitvivmLtslvelgrek......................................caqywplggsleygdftvtllsvevkddytvr
-------KelirhignqvniiitilavmfllpidkifgthffpR---------------------------------Lysrlvirhqslyqqymdyleys
. .
tleltnly...................................dgesrtvlhiqytdwpdhgvppsfedlldfieavr......................
kpvfsgmlkllLSH---EENLPVLIHCVYGKDRTGVLVALILD------CIGVER
. ... |||.|| |..|||...|. | ||
...........kaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdl
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 46-216 | 2.3e-09 | 32.7 | In-house | 60-203 (243) | alignment | ||
Range on Protein: 46-216
Range on HMM: 60-203/243.0
VTAKDKSLFLQLGIKSIIDIRGEKEYRKLTSRPLDNlytPTVITDNKTSDLTEHKdtsvgrrylfdV-----------Fskelirhignqvniiitilav
..|.. .. .|||..|.... ..|. .. .. . .| .. | |.. . .
dlasfwrmlwelgitvivmltelvElgrekcaqywp...gevtygdftvtllsee...........hlddytvrtllle.....................
mfllpidkifgtHFFPRLYSRLVIRHQSLYQQYM----------DYLEYSKPVFSGMLkLLLSHEENLPVLIHCVYGKDRTGVLVALILDCI
. . ..||||... | . |.|.. . . . .| .|| .. |||.||. |..|||.|.|. | .
............nldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieell.sllaldsggpvlVHCsaGvgRtGtliaaylmll
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 47-216 | 4e-09 | 32.0 | In-house | 36-134 (176) | alignment | ||
Range on Protein: 47-216
Range on HMM: 36-134/176.0
TAKDKSLFLQLGIKSIIDIRGEKEYRKLTSRPLDNLYTPTVItdnktsdltehkdtsvgrrylfdvfskelirhignqvniiitilavmfllpidkifgt
.|.. ....|||. .... |.|. .| . .... |
ladflemlkelgitavvnlteevelgrlkcpnywpeleklgi..........................................................
hffprlysrlvirhqslYQQYMDYLEYSKPVFSGMLKLLLSHEENL----PVLIHCVYGKDRTGVLVALILDCI
.... ... | .. .|.|| .| | |||.||. |. |||.|||. | .
.................qylhlpwpDhgvpdlelllellefirealkeggpvlVHCsaGigRtgtlvaayllel
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 47-217 | 1e-08 | 30.5 | In-house | 22-115 (152) | alignment | ||
Range on Protein: 47-217
Range on HMM: 22-115/152.0
TAKDKSLFLQLGIKSIIDIRGEKEYRKLTSRPLDnlytptvitdnktsdltehkdtsvgrrylfdvfskelirhignqvniiitilavmfllpidkifgt
.|... .. .|||. |. . . | || .
ladfwrmlkelgittivmltellelgklkceqyi..................................................................
hffprlysrlvirhqslYQQYMDYLEYSKPVFSGMLKLLL------SHEENLPVLIHCVYGKDRTGVLVALILDCIG
... .. | .| .|. || .... |||.||..|..|||.|||. | . |
.................qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylmllg
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 48-213 | 6.7e-10 | 34.3 | In-house | 48-131 (182) | alignment | ||
Range on Protein: 48-213
Range on HMM: 48-131/182.0
AKDKSLFLQLGIKSIIDIRgEKEYRKltsrpldnlytptvitdnktsdltehkdtsvgrrylfdvfskelirhignqvniiitilavmfllpidkifgth
|.. .. .|||..|.... | |
adflrmlkelgittivnlt.eelywp..........................................................................
ffpRLYSRLVIRHQSLyqQYMDYLEYSKPVFSGMLKLLLSheENLPVLIHCVYGKDRTGVLVALIL
|. ||.|... | . |. . . . ... |. |. |||.|| .|..|||.|||. |
...ellerlgiqylyl..pwpDhgvpdldelldfieevle..eggpvlVHCsaGvgRtgtlvaayl
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 49-227 | 1.2e-10 | 36.7 | In-house | 67-218 (245) | alignment | ||
Range on Protein: 49-227
Range on HMM: 67-218/245.0
KDKSLFLQLGIKSIIDIRGEKEYRKLTsrpldnlytptvitdnktsdltehkdtsvgrrylfdvfS----------------K-----------------
. .. .|||..|.... | |. . . .
dfwrmlwelgittivmLteeeelgrvk......................................caqywplgesltygdftvtllseehlddytvrtle
-----ElirhignqvniiitilavmfllpidkifgthffprLYSRLVIRHQSLYQQYMDYLEYSKPVFSGMLKLLLSH--EENLPVLIHCVYGKDRTGVL
. .|| ||... | .. .... ... . .. .| |||.|| |..|||..
vtnlgd...................................desrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtf
VALIL------DCIGVERETIAMDY
.|. | || | . ..
iaaylmleqlekelgvsleeavkel
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 96-223 | 7.4e-09 | 30.9 | In-house | 170-248 (278) | alignment | ||
Range on Protein: 96-223
Range on HMM: 170-248/278.0
LtehkdtsvgrrylfdvfskelirhignqvniiitilavmfllpidkifgthffprlysrlvIRHQSLYQQYMDYLEYSKP-VFSGMLKLLLSH-----E
.. . .|.. ... | .| .|..|
g.............................................................esrtvthyhylgwpdhgvpeslsllldflkavrealed
ENLPVLIHCVYGKDRTGVLVALILD------CIGVERETI
.| |||.||. |..|||...|| | || | .
sngpvlVHCsaGvgRTGtfialyllleqlekeggvdleea
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 115-238 | 1.4e-09 | 33.6 | In-house | 192-283 (307) | alignment | ||
Range on Protein: 115-238
Range on HMM: 192-283/307.0
KelirhignqvniiitilavmfllpidkifgthffprlYSRLVIRHQSLYQQYMDYLEYSKPVFSGMLKLLLSHE---ENLPVLIHCVYGKDRTGVLVAL
. .|| |. .. . .. .. ..... . ... .| .. |||.|| |..|||...|.
g.....................................esrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaa
ILDCIGVERETIA--MDYASSEDGLVSMR
| . ..|.| . .|. . . | ..|
ylmlrqlekegtlldvdlleavkllreqR
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 145-230 | 1.3e-11 | 40.3 | In-house | 168-253 (314) | alignment | ||
Range on Protein: 145-230
Range on HMM: 168-253/314.0
GTHFFPRLYSRLVIRHQSLyqQYMDYLEYSKPVFSGMLKLLLSHEENLPVLIHCVYGKDRTG--VLVALILDCIGVERETIAMDYASS
. .. | |..||.|.. . |. . . | .|......... |||.|| ||.||| |..|... . || |.. |. .
eelydpelferlgikylri..pvpDgsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlk
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 152-218 | 1.2e-08 | 30.2 | In-house | 151-233 (278) | alignment | ||
Range on Protein: 152-218
Range on HMM: 151-233/278.0
LYSRLVIRHQSLYQQYMDYLEYS--KPVFSGMLKLLL--------------SHEENLPVLIHCVYGKDRTGVLVALILDCIGV
|.|| | .. | .. ... |.... . .. .... |||.|| .|..|||.|||. | . .
lesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell
|
|||||||||
Y_phosphatase3 | Tyrosine phosphatase family | 159-230 | 2.3e-19 | 65.0 | Pfam-A | 94-163 (164) | alignment | ||
Range on Protein: 159-230
Range on HMM: 94-163/164.0
RHQSLYQQYMDYLEYSKPVFSGMLKLLLSHEeNlPVLIHCVYGKDRTGVLVALILDCIGVERETIAMDYASS
.... . | ..|| .|. .. .|..|...| . |||.|| |||||||..||.|. .||..|||| ||. .
aeeamaeayreiledekkayrkvlealaeee.g.pvlfHCtaGKDRTGvvaalllsllgvdeetiaaDYllt
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 161-219 | 4.1e-07 | 25.1 | In-house | 174-235 (297) | alignment | ||
Range on Protein: 161-219
Range on HMM: 174-235/297.0
QSLYQQYMDYLEYSKPVFSGMLKLLLSHE---ENLPVLIHCVYGKDRTGVLVALILDCIGVE
. . .. |. ..... . ... .. .. |||.||. |. |.|...|. | . .|
hytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqle
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 165-217 | 7e-08 | 27.6 | In-house | 177-235 (317) | alignment | ||
Range on Protein: 165-217
Range on HMM: 177-235/317.0
QQYMDYLEYSKP-VFSGMLKLLLSHEE-----NLPVLIHCVYGKDRTGVLVALILDCIG
.|... ... | .. .|..| .| . |||.||. |..|||...|. | .
fhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleq
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 165-220 | 5.8e-07 | 24.7 | In-house | 171-234 (273) | alignment | ||
Range on Protein: 165-220
Range on HMM: 171-234/273.0
QQYMDYLEYSKP-VFSGMLKLLLSHE-------ENLPVLIHCVYGKDRTGVLVALILDCIGVER
.|.. ... | .. .|... . .| ||..||. |. |||...|| | . .|.
fhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlek
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 165-216 | 1.9e-06 | 22.1 | In-house | 203-256 (300) | alignment | ||
Range on Protein: 165-216
Range on HMM: 203-256/300.0
QQYMDYLEYSKPVFSGMLKLLLSHEENLPVLIHCVYGKDRTGVLVA--LILDCI
.....||| . | . . |.|.. |||.|| | |||||. |.. ..
kgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 166-215 | 1.8e-08 | 29.7 | In-house | 189-246 (297) | alignment | ||
Range on Protein: 166-215
Range on HMM: 189-246/297.0
QYMDYLEY-----SKPVFSGMLKLLLSHE---ENLPVLIHCVYGKDRTGVLVALILDC
||.. .. .. ... . .. .. .. |||.||. |..|||...|. | .
qytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylml
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 166-226 | 7.7e-07 | 24.3 | In-house | 171-241 (284) | alignment | ||
Range on Protein: 166-226
Range on HMM: 171-241/284.0
QYMDYLEYSKPV-FSGMLKLLL----SH---EENLPVLIHCVYGKDRTGVLVALILDCIGVERETI--AMD
.|.. ... | .. .|..| .. . . |...|| |. |||...|| | . .|.| . .|
hytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvd
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 166-221 | 9.3e-07 | 24.0 | In-house | 188-249 (288) | alignment | ||
Range on Protein: 166-221
Range on HMM: 188-249/288.0
QYMDYLEYSKPV-FSGMLKLLLSH-----EENLPVLIHCVYGKDRTGVLVALILDCIGVERE
.|.. ... | .. .|..| . ||..|| |..|||...|| | . .|.|
hytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqleke
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 175-225 | 1.2e-06 | 23.6 | In-house | 217-265 (308) | alignment | ||
Range on Protein: 175-225
Range on HMM: 217-265/308.0
KPVFSgMLKLLLSHEENLPVLIHCVYGKDRTGVLVALILDCIGVEREtIAM
..... .|.|. .. .. |...|| | |||...|| | . .|.| .
eilld.flelvrkslpggpivVHCsaGvGRtGtfialdllleqleke.ggv
|
|||||||||
Y_phosphatase2 | Tyrosine phosphatase family | 177-212 | 4.9e-07 | 21.7 | Pfam-A | 78-112 (165) | alignment | ||
Range on Protein: 177-212
Range on HMM: 78-112/165.0
VFSGMLKLLLShEENLPVLIHCVYGKDRTGVLVALI
. . .||||| .|| |||.|| || |||.... .
llkkalkllln.kenypvllhckrGkhrtglvigcl
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 179-213 | 1.3e-06 | 23.7 | In-house | 103-137 (194) | alignment | ||
Range on Protein: 179-213
Range on HMM: 103-137/194.0
SGMLKLLLSHEENLPVLIHCVYGKDRTGVLVALIL
... |. .. |..||..|. |||.||| |
ldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYL
|
|||||||||
PTPc_DSPc_SM00012 | 183-241 | 3.8e-07 | 25.6 | In-house | 38-89 (105) | alignment | |||
Range on Protein: 183-241
Range on HMM: 38-89/105.0
KlllsheeNLPVLIHCVYGKDRTGVLVALILDCIGVERETIAMDYASSEDGLVSMRNEM
. . ||..|| | .|||..||| . . .|.|| .| | ..|. |
s.......skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgm
|
|||||||||
Y_phosphatase3C | Tyrosine phosphatase family C-terminal region | 258-299 | 3.4e-11 | 32.6 | Pfam-A | 26-68 (68) | alignment | ||
Range on Protein: 258-299
Range on HMM: 26-68/68.0
AKADTMLKVLNEIDKRYGSTSQYL-ESIGFTLEDQESLKSILL
...... .| .||.|||| .|| | .|.. ||.| |.. ||
vreeyleaaldtideryGsvegYLeeaLGlseedierLRerlL
|