Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
0051299 | (Phosphotyrosine protein) phosphatases II | 9-299 | 1.8e-91 | 301.9 | In-house | 4-286 (288) | alignment | ||
Range on Protein: 9-299
Range on HMM: 4-286/288.0
TLKLNEFLDHFMSLAednEENDATFNKEFQALKMESQRykdqntFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEY
....|.|.... | . ... .||..| .. ... | |..|||..||||....||.|. ..||||||||||.||.|.. . ..
eisveellklvlkll...angltglleefeellsllpd......ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkf
IAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQvGESAMYGAIQVTTDHEENvSNDFIIRQLTAE------CQGEKQVIRQFHYTAW
||.|||||.||.|||||.| .......| ...||. . || |||. |.| .|| |.||. .|| .|...|.|. . ..||.. ...||||.|
IatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl.ggsltygditvtllseev.lddytvrtlevtnldlldgdgesrtvthfhytnw
PDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
|||| |.|...........|.... .. | ..|||||.|||||.||.| . .| |. ..||...|...|.||| ||| ..||.|||.|..|..
pdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqleke...ggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 10-302 | 2.6e-90 | 297.4 | In-house | 7-288 (293) | alignment | ||
Range on Protein: 10-302
Range on HMM: 7-288/293.0
LKLNEFLDHFMSLAEDneeNDATFNKEFQALKMESqryKDQNTfpaESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYI
.||..| .|......| .|. |..|.. || |||.. .. ...||..|||...|||....||.|..... .||||||||||.| . |.|
iklekfeehvkkmkad...sdlrfseeyeelkavg...kdqav...kaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefi
AAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGAIQVTTDHEENvSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPE
|.|||||.||.|||||.| .. .|..| . || | ||. |||. |. .|| |.|| .||. .|..||.|. | . |.. .||.|.|.||||| ||
atqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeee.ledwvirelkiekekeerkvrqyhftsWpdhgvPe
SATPIIRMIEMFREHR--KRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKktiPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
............||. . .. | .||||| ||||| ||.| . . | .|.|.||...|..| .||. .||.|.. ....|....
ktktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaiee...edyvdifgivaelReeRnllvqtekqYifihqcvldllrkk
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 10-306 | 7.5e-82 | 269.9 | In-house | 5-292 (319) | alignment | ||
Range on Protein: 10-306
Range on HMM: 5-292/319.0
LKLNEFLDHFMSLAEdneENDATFNKEFQALKMESQRykdqntfPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYI
....|. .... ||. . ...|||. ||. .. .| ... ||||||...||... |||.| ...||||||||||..|.| . ....|
ievqeLkerlkalas...tgetllekefkllkeavnd.......tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfi
AAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQvGESAMYGAIQVTTDHEENvSNDFIIRQLTAECQGE---KQVIRQFHYTAWPDHG
|.|.|| .|..|||||.| ... ||.| .. || | |.. |||. . || . || ..||. .|.|||.|. . . . . .|.||.||||.
atqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpe.enfeeyGrlivtleeeee.ledyiirklklnkkssevetRevkhfqyteWpdhd
RPESATPIIRMIEMFREHRKR-HDIPFAIHCSAGCGRTGTIIAIDFartMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTN
||.|| .. ... |. |.. .. | .||||| ||||| |..| || . |||||.|...| ||. ||| .|| |.| |..| |. |.
vPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivlda...mlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdte
--V
|
iev
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 11-306 | 4.1e-78 | 258.0 | In-house | 2-294 (563) | alignment | ||
Range on Protein: 11-306
Range on HMM: 2-294/563.0
KLNEFLDHFMSLAEDneeNDATFNKEFQALKMESQrykdQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGS-DYINANYIQGPDGNVEYI
...|| | .|| | .| |..||.||..|.. .....||. |.| ||.||| .|.... .||.|... |.... ||||||||.| . ..|
pvkefakhvaslhad...gdigfseefealqseti....skdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafi
AAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQvGESAMYGAIQVTTDHEENVS----NDFIIRQLTAECQG---EKQVIRQFHYTAW
|.||||..|..||||||| .. .|..| || . ||. |||. || |||.||| .|| .. . ..|..| . . .....||.||| |
atqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkW
PDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
|||| ||...| . ... .|.. | .||||| ||||| |..| . .. .. .|| .....| ||. .|| .||.|.. |..|...
PdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqe...navnvfgflkhiraqRnflvqteEqYiflhdalleaiask
LTNV
|..
etel
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 13-305 | 7e-87 | 286.4 | In-house | 5-286 (318) | alignment | ||
Range on Protein: 13-305
Range on HMM: 5-286/318.0
NEFLDHFMSLAEdneENDATFNKEFQALKmesqRYKDQNTfPAESgQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQ
... .| | | . . ....|...|. | ... | .| .||||.|||. .||... |||.|...||.|||||||||||.| . .|||||
edleshvrrlre...sGelllseeyerls....rseetvt.slks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaq
GPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGeSAMYGAIQVTTDHEENVSnDFIIRQLTAECQGE--KQVIRQFHYTAWPDHGRPES
.|||.|..|||||.| . ...| .|.| .| |.. |||. | | ||...|. ..| ..| |...|... . ..| ....||.|||.|||.| |||
aPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskg.srsygklvvelkeevels.dyvlrefkvtrteeeesrqvrqyhytsWpdegvpes
ATPIIRMIEMFREHR-KRHDIPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTN
.. .. .. .. | | ..||||| ||||. ||.| ..| . .||| .|.|.|.||..|||. |||.|.| ...| .. |.
gaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavd...illerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdte
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 13-301 | 4.3e-64 | 211.2 | In-house | 5-285 (290) | alignment | ||
Range on Protein: 13-301
Range on HMM: 5-285/290.0
NEFLDHFMslaEDNEENDATFNKEFQALKMESQrykdqnTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEG--SDYINANYIQGPDGNVEYIA
..| .. . ... ... .|...|..|. .. . .. | . ||..|||..|.. . |. |..| | . .|||| ||.| . .|||
dkfgefva...nghakgnegfrnqfkmldsges......ehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyia
AQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVgESAMYGAIQVTTDHEENVSnDFIIRQLTAECQ---GEKQVIRQFHYTAWPDHG-
.|||...|. |||..|| ... |..| . ..|. | ||| |||. ....|| .... .||... ..|.|.| . . |.|| . |.. |.|...|
tqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds.dtkaygefsikllneetln.eyierklevknknsagakqsvtqyqitnwdstgk
RPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
.. .| .. . || . .||| . . .|||.. ||... .|.. | . | . |||......| |.| .||. .|| ... ... ...
vtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaa...ttinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 13-299 | 2.2e-56 | 186.2 | In-house | 5-279 (439) | alignment | ||
Range on Protein: 13-299
Range on HMM: 5-279/439.0
NEFLDHFMSLAEDNEEndaTFNKEFQALKMESQRYKDQNTFPAESgqnpVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQ
.|| .| | ...| |...|. .. | |. . .. |.. .. |||.||. .|..||| |..| || | |||||||.| . |||.|
defqehvekldknkqe...ifkeifekinstspdyaciaslaaqe....ydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatq
GPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKpkcqcYWPQVGEsAMYGAIQVTTDHEENVSNdFIIRQLTA---ECQGEK-QVIRQFHYTAWPDHGRP
|| .|..||||... .. ..| . || | ||| .| ..|| | | .|.. .. | ..|| . ..|| . . ||||.||||. |
gpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdae.vcygdiavrvdrnielpn.yvirgfkvfnerdttekertvlqfhyiawpdknvp
ESATPIIRMIEMFREHR-KRHDIPFAIHCSAGCGRTGTIIAIDFARTMLikkTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
|. .. .. |. | .||||| ||||||||.| | | . .|.|. ||. .|||| ||||| ||||.| |..| .
aqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeql...klenkvdikgivkvlrkqrkqmvqalcqyvfiynavledi
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 16-301 | 5.5e-89 | 293.8 | In-house | 32-301 (308) | alignment | ||
Range on Protein: 16-301
Range on HMM: 32-301/308.0
LDHFMSlaednEENDATFNKEFQALKMESQrykdqnTFPAESGQNPVNKKKNRFKDILPFEYTRVQLhkieGvEGSDYINANYIQGP--DGNVEYIAAQG
| .... . ...||..| . .. .... | ||.|||.|||||....|| | . ||||||||.|..|. . . ..||.||
lkllek.....aldlglleeefeellsvkp......lleysvallpenkdkNrykdilpydhsRVkl....d.egsdYInAsyvdgyssklprkfIatqg
PLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQV--GESAMYGAIQVTTDHEENvSNDFIIRQLTAEC--QGEKQVIRQFHYTAWPDHGRPE
|||.||.|||||.| .......| ...||. ..|| ||| |.| .|| ..||. .||. .|...|.|. .. || ....||||.||||| |.
PlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.lddytvrtleltnlgdgesrtvthfhytnWpdhgvPp
SATPIIRMIEMFREHRkrHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
|........|. |... . | ..|||||.|||||.||.| . .| |. ..|||..|...|.||| ||| ..||.|.|.|..|...
speilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqleke...ggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 20-301 | 7.2e-55 | 180.8 | In-house | 18-294 (297) | alignment | ||
Range on Protein: 20-301
Range on HMM: 18-294/297.0
MSLAEDNEENDATFNKEFQALKmesqRYKDQNTfPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDG-NVEYIAAQGPLPHT
.| || .| ..||..||. .|. ... .| .... | |||| |..||.. .||.|.. | |||||| | | . |||.||||..|
lsyledhlknkdrlekewealc....ayeaeps.tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplast
VNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGeSAMYGAIQVTTDHEENVSNDFIIRQLTA--ECQGEKQVIRQFHYTAWPDHGRPESATPIIR
| |||.|.| . . .... .| | .|. |||. | |..|.. .| | ..|...| . . | . . |||. .||..| | || ...
vadfwqmvweqGvvvivnltrleeegvkqckrywpdeG.sevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasakslle
MIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
. . | .|||.|.||||. |.||. . |.| ..|. . .. .| ||| .|.. ||. |...|..| |..
frrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGv..keidiaatlehlrdqrpglvktkdqfefaltavaeevna
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 21-310 | 1.2e-71 | 236.6 | In-house | 24-304 (319) | alignment | ||
Range on Protein: 21-310
Range on HMM: 24-304/319.0
SLAEDNEENDATFNKEFQALKMESQRYKDQNTfpaesGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVN
| .| ... .. ||... . ||. . || |||. .||.|. ..|.|....|.|.|||||| ...| . ||||||||. |..
snksdfdddltklevefrracklgvnladqtf.....anldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntla
DFWRMIWYHQIEIVIMACrevemaKPKCQCYWPQVGESaMYGAIQVTTDHEENvSNDFIIRQLTAECQ---GEKQVIRQFHYTAWPDHGRPESATPIIRM
||||||| ... ... | || |||. .. .. .| | |. ......|.. . ... |.|||. |||.| |.......|.
dfWrmiweyncstivllt......kdkcsqywplkivi.keerfkvkvdsvee.taeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrl
IEMFR--EHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLikkTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE--LVQQSLTNVPQLP
.. | .....| . .|||||.||||. |..| .. ...||. .|...|.||. .|| | || |.|.|..| |. .| .|..|
vkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrm...keekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfp
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 22-302 | 1.7e-75 | 249.0 | In-house | 13-289 (307) | alignment | ||
Range on Protein: 22-302
Range on HMM: 13-289/307.0
LAEDNEENDATFNKEFQALKMEsqrYKDQNTfpaESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVND
| ... | . ||.. |. . |..| . ... |. |||..|| .|. |||.|.||.| | ||||||..|.| . . ..||||.|. |..|
lksrkrdtdfglakeyekLear...eidkst...kvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigD
FWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVgESAMYGAIQVTTDHEENvSNDFIIRQLTAECQG-------EKQVIRQFHYTAWPDHGRPESATPI
|||||. ......| . |. . ||. |||. . || | |.. .||. .|.|||.| .. ... . |.|||.|.| ||.|. .
fWRmiaeqevtlivmlsnlteknrkkcakYWpie.devqygdilvklvseek.hsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargl
IRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
...||. ||. | . | .||||| ||.|...|.| .| . ||.|.| .|...|.||. .|| |.||||.| |... . .
lklieqvrelyklnrsPivvhCsaGvgrsgifvald...sllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssyg
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 23-306 | 1.1e-71 | 236.5 | In-house | 14-290 (305) | alignment | ||
Range on Protein: 23-306
Range on HMM: 14-290/305.0
AEDNEENDATFNKEFQALKMEsQRykdqntfPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDF
|.. ..| ........| .| . . . |.. .||.|||.|.| ... |..| . | .. ||||||.|..| ... .||.|||||..||.||
kearvysdkgleaqykslyee.ee.......sidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadf
WRMIWYHQIEIVIMACREVEMAKPKCQCYWPQ-VGESAMYGAIQVTTDHEENvSNDFIIRQLTAEC---QGEKQVIRQFHYTAWPDHGRPESATPIIRMI
||.|. ... ..| .. || | ||. |||. ..|. .| ..|. |.. .|.|.|.|.. . |.... |.. | ||||| |..|| ....|
WrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksekt.asdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllsli
EMFREHRKRH-DIPFAIHCSAGCGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTNV
. ....|. . | .||||| ||||. ||.| | | | . .||| ...|.|..|. ||| ||||||.. |. ||.. |..
krvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkE...evvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsi
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 23-302 | 2.2e-62 | 205.6 | In-house | 12-281 (287) | alignment | ||
Range on Protein: 23-302
Range on HMM: 12-281/287.0
AEDNEENDATFNKEFQALKMESQRyKDQNTFPAesgqNPVNKKKNRFKDILPFEYTRVQLHkiegVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDF
|....... |.. |. |. .|| .|. | . ||.|||...||. . || |. | ||||| .|.| . ..|.|..|. .|. .|
akghakgnegfknqftvleqvtqr.edevthni....asqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnf
WRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVgESAMYGAIQVTTDHEEnVSNDFIIRQLTAEC---QGEKQVIRQFHYTAWPDHG-RPESATPIIRMI
|..|. .......| |.| | . .| |||. .| ..| ... .|| |....|.|.| . .|.|| ..|...|.|...| .| .| .. .
WkliddrnvtaivmlcqekendeevcyqyWpee.ksvvlGeyniellnee.vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvie
EMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
||....||| . . .|||.. ||... .|.. | . | .|||......| |.| .||. .|| |.. ...| ..
emyktqrkrgntsivvhCsdtvGrsamfcaaa...ttinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsf
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 24-301 | 9.1e-79 | 259.6 | In-house | 19-299 (306) | alignment | ||
Range on Protein: 24-301
Range on HMM: 19-299/306.0
EDNEENDATFNKEFQALKMESqrykDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHkIEGVEGSDYINANYIQ--GPDGNVEYIAAQGPLPHTVND
|... . | |..||..|. | .... . |. | ||.|||.| ||||. ||| |. ..| ||||||||||. .. . .|||.|| |..||.|
eeeslekagfeeefeelqqee....akkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsd
FWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGAIQVTTDHEeNVSNDFIIRQLTAE---CQGEKQVIRQFHYTAWPDHGRPESATPIIRMI
||||.| . ....|. .||| .| || |||.. |. .|| |.||. .| . .|.|.|.|. . ..|.. ..|.|...||||| |.. .. ..
FWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvse.ksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfl
EMFREHRKRHD----IPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
| ...... | .||||| |||||.| || .. || . ..|. ..|...|.|| .|| .|| |||.|| . ...
edvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyiet
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 24-301 | 1.1e-75 | 249.7 | In-house | 20-292 (298) | alignment | ||
Range on Protein: 24-301
Range on HMM: 20-292/298.0
EDNEENDATFNKEFQALKMESQRYKDQNtfpAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFW
..... .....||| |. |.. .... | ...| ||||||. ||......|| |.|... | |||||| .... .|. .||.|.||..||.|||
vkkkkkltgyalefqrlnsvsseieeee...kevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFW
RMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGeSAMYGAIQVTTDHEEnVSNDFIIRQLTA--ECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMF
||.. ..|. ..| .|. | |.. |||..| .. || |.|. ..| . |.|.|.|. . . ... .||.|.| |||.| || || .. ...
rmvteedigtiVmltnleeldktkyhkywPdeg.ketygeitvsllske.efadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkv
REHRKRHD-IPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
| .... | ..|||| ||.|| |||| ..| . . ..||| .|. .||.||..||. .||||.|.|. | ..
rasqqqagnkpvivqCsaGvgRsGtfiaid...svlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealds
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 24-303 | 2.3e-73 | 241.7 | In-house | 8-280 (281) | alignment | ||
Range on Protein: 24-303
Range on HMM: 8-280/281.0
EDNEENDATFNKEFQALKMEsqrykdQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFW
. .....| | .|...|. .. .|.. ... |..|||...| .. |||.... | . .||||||...| .|. ||||.|||.|.....||
qlsqndnaGfieeyeklaai......gvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafW
RMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGAIQVTTDHEENvSNDFIIRQLTA-ECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMF-
.|.| .......| ||.| | || |||. .. || ..|.. .||. .. .| |... ...||.. ..|..|||||||| |.... .. .
qmvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeee.katyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevl
REHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSL
. ..|....|. |||||| ||||| ||.| . . ... .||| .|...||.| |||.. || ||| |... ... |
kltekktkaplvihCsaGvGrtGtyialDrlvkaveael..eeldvkavvaelrkernlmvqtvvqyefvykavldaldkel
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 24-113 | 4.1e-10 | 33.7 | In-house | 16-95 (95) | alignment | ||
Range on Protein: 24-113
Range on HMM: 16-95/95.0
EDNEENDATFNKEFQALKMESQRykdqntfPAESGQNPVNKKKNRFKDILPFEYTRVQLHKiegVEGSDYINANYIQGPDGNVEYIAAQG
| . | |..||... | | | | | |||| .|.|.. ||| | |||||| ...| . ||||||
emhsnsdqefdnefksismtsga.......pytvgsseanipknrflnifpydatrvvltt...krdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 25-309 | 6.9e-141 | 463.2 | In-house | 2-287 (290) | alignment | ||
Range on Protein: 25-309
Range on HMM: 2-287/290.0
DNEENDATFNKEFQALKMESQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWR
...|....|.||||.||..|..||.......|.|....|.||||.|||||....||.|.|||..|||||||||.|.|..|..||||||||||.|..||||
eekegeeefakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWr
MIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAM-YGAIQVTTDHEENVSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFRE
|||....|||.|||||||..| ||..|||. ||... .|...||...|..|..||.||.|..|.|.|.....|||||||||||.|.||......||..||
miweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvre
HRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTNVPQL
.....|.|...|||||.||||||||||..|..| ...||..||||..|...||||.|.||. .||..||.|..||||..|.....
lqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqkeleiieek
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 25-305 | 1.3e-82 | 272.1 | In-house | 15-286 (288) | alignment | ||
Range on Protein: 25-305
Range on HMM: 15-286/288.0
DNEENDATFNKEFQAL-KMESQRYKdqntfpaESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFW
. .| . |..|...| ..|... . . |...||.||||...|||....||.|.| | ..|.|||||.||.| ... .|||.||||..||||||
ksarnrtgfseeynsLaalektksv.......tagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfW
RMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGAIQVTTDHEENvSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFRE
.... .... ..| || | ||. |||. .. || ..|| .... .||. |.| | .... | |..|.|||||| |||..|.. ....
elvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveske.ledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkv
HRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKktiPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV-QQSLTN
. |. .||||| ||||| ||.| . .. . |..||...|...||||. .|| | ||.|.| ....|. ......
anqadtgpiivhCsaGvGrtgtFialdalidavee...edyiDvagtvaklRkqRallvqtlkqYefiyevllslieedgvae
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 25-303 | 1.6e-58 | 192.8 | In-house | 9-284 (288) | alignment | ||
Range on Protein: 25-303
Range on HMM: 9-284/288.0
DNEENDATFNKEFQALKMESQRYKDQNTFPAesgqNPVNKKKNRFKDILPFEYTRVQLHkiegVEGSDYINANYIQGP-DGNVEYIAAQGPLPHTVNDFW
.. ....|.|. |... .. ... . .. .|||..||||.. .||.|. . ||||| .... | ..||.|.||. |.||||
kmldgktaldkkfkeleqkqdkearkrsiai....aklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFW
RMIWYHQIEIVIMACREVEMAKPKCQCYWPQ-VGESAMYGAIQVTTDHEENvSNDFIIRQLTAECQGEK--QVIRQFHYTAWPDHGRPESATPIIRMIEM
.|.. . ....| . |. |||.. |||. ||. .|...|| .... .. .. |.|. | .... . .. ..|.||..| |.| ......
lmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvre.tethvervlkletldadavksvshlqltsWpelGvPasPetllqflde
FRE----HRKRHDIPFAIHCSAGCGRTGTIiAIDFARTMLIkKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSL
.. .... ..| .||||| ||||.. |. .| . .. . ||. .|...|.|| ||| .|. |.| |..| ... |
vesayeavqrksktPlvvhCsaGvgRtgvf.alvyaavrel.ekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarrvl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 26-303 | 8.7e-34 | 111.7 | In-house | 1-263 (267) | alignment | ||
Range on Protein: 26-303
Range on HMM: 1-263/267.0
NEENDATFNKEFQALKMESQrykDQNTFPAESGQNpvNKKKNRFKDILPFEYTRVQLHKIEgvegSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRM
||... ..|||. .| |. ...| ... |...||. | ||.. ||| | . | .|||| |..| . .|. |.|| |. ||. .
nedeeceiekefelikkisd...tsstisqsiaek..nqernrlddnlpyddtrvilrtke....eeyinasyvegyktknafivtqdplkntitdfltv
IWYHQIEIVIMACREVEMAKPkcQCYWPQVGESAMYGAIQVTTDHEeNVSNDFIIRQLTAECQGEK-QVIRQFHYTAWPDHGRPE-SATPIIRMieMFRE
| ... .... . . . . . |..|.. | . | | . ||. | | . . | . . ..| | . |.. . . ..
ihdqkvpvivlltkvftdnir..lfwPPkmgqakkyqdltvehsle.keendyqiitlelkfknesahnvtlyyykkwnintnnkpylkplfgi..lakn
HRKRHDIPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSL
. . . |. ..||.| ||.|| . || ..| . . .|.| ....|.||...|.....|.... ..| . |
qlengnrPlvvacsdGvGrsGtflvid...sqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeyaegrl
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 28-307 | 2.1e-97 | 322.1 | In-house | 20-289 (564) | alignment | ||
Range on Protein: 28-307
Range on HMM: 20-289/564.0
ENDATFNKEFQALKMEsqrykdqNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIW
..|..|..|.. .... ..|. |. ..|.||.|||...|.... .|| |.|.||.||||||||..|.| . . .|||.||||..|..|||||.|
nsdlkfeeeykkieeg.......qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvw
YHQIEIVIMACREVEMAKPKCQCYWPQVGeSAMYGAIQVTTDHEENVsNDFIIRQLTA--ECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHR
.......| . .|. | ||..|||. | .. || ..|| .||.. .|..||... . . |.. .||||.|.||||| |||||.....|. |...
eqnsstiVmltkleEkgkvkchkYWPekg.tetygeltVtleeeeel.adyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln
KRHDIPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTNVP
... | .||||| ||||| |.|| || . . ...|....|...||||.|||| .||.|.. ||.| .. |.|.
epdagPivVhCSaGVGRTGtfivid...amlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnteve
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 28-298 | 4.4e-55 | 181.5 | In-house | 7-276 (287) | alignment | ||
Range on Protein: 28-298
Range on HMM: 7-276/287.0
ENDATFNKEFQALKMESqrykDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHkIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIW
. .||..||| .| . |. . .. . ||||. |.||.. ||| | || |||||||||. . . ..||||||.. ||.||||...
rvkddvdkevdalkeds....esstatfkaaeelaavkknryadvlPiddtrvlls.aegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravl
YHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGAIQVTTDHEENVSNDFIIRQLT-AECQGEK-QVIRQFHYTAWPDHGRPESATPIIRMIEMFREH-
.. ||. |||| |. || |||. . | |. .. . .. .| | .. .... .|..|... .|||.. . .| .||.. ..|
etrsasvitmtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhi
---RKRHD-IPFAIHCSAGCGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
|. . | .|...| ||.|...|. .| . ..|| .| ..|..| |.||| |. ..| |.|
elardasevGPlvvhddvGiGrsGillatlvlvsrledl...Grvdvaavvirlreyraalvqavvqlrllyealvty
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 29-299 | 5.9e-85 | 281.0 | In-house | 25-304 (307) | alignment | ||
Range on Protein: 29-299
Range on HMM: 25-304/307.0
NDATFNKEFQalkmESQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGV-EGSDYINANYI--------QGPDGNVEYIAAQGPLPHTV
. . . |||. . ...... .. .... |.||.|||.|||||...|||.|. ..| |.||||||.|. .|.| . ..||.|||||.||
fltgllkefe....kllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetv
NDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGAIQVTTDHEENvSNDFIIRQLTAE---CQGEKQVIRQFHYTAWPDHGRPESATPIIR
.|||||.| .......| ...||....|| |||. ||. .|| ..||. || .....|.|. . || ...||||.||||| |.| ....
edFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelld
MIEMFREHRKR--HDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
.||. |..... . | ..|||||.|||||.||.. . ..| | . .|....|...|.||| .|| ..||.|.|.|. ||.
fieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 29-298 | 8.7e-85 | 279.8 | In-house | 10-271 (273) | alignment | ||
Range on Protein: 29-298
Range on HMM: 10-271/273.0
NDATFNKEFQALKMESQrykdqnTFPAESGQNPVNKKKNRFKDILPFEYTRVQLhkieGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWY
. ... .||..|. .. . .. | ||.|||.|||||....|| | | .|||||||.|..|.. . ..||.|||||.||.|||||.|
gltllleefelllslkp......lltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvwe
HQIEIVIMACREVEMAKPKCQCYWPQVGE--SAMYGAIQVTTDHEENvSNDFIIRQLTAEC--QGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREH
.......| ...||. ..|| |||. |. | .|| ..||. ||. .|...|.|. . ||. ....|||| ||||| |.| ......||. |..
qnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseet.kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrka
RKR--HDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
.. .. | ..|||||.|||||.||.| . .|.|. ..||...|...|.||| ||| ..||.|.|.|..|.
lealpsngpvvVHCsaGvgRtgtfialdllldqleke...ggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 29-305 | 5.5e-26 | 85.7 | In-house | 15-291 (302) | alignment | ||
Range on Protein: 29-305
Range on HMM: 15-291/302.0
NDATFNKEFQALKMESQrYKDQNTFPAESGQNPV---NKKKNRFKDILPFEYTRVQLHKiegvEGSDYINANYIQGPDGNVEYIAAQGPLPHTV---NDF
. ...|.... ..... .| .|. .. . .. | |||. .|. . ..|.|.. | .|.|| .. |. . . | || | .. ..|
eakklvksldtaevkke.fkkidtmkvdlekCkafkknlkknqsedvpildsnlvklea....epdsyvnaskvevPeltrsiilaQlpkvdsedsveeF
WRMIWYHQIEIVIMACREVEMAKpKCQCYWP-QVGESAMYGAIQVTTDHE---ENVSNDFIIRQLTAECQgEKQVIRQFHYTAWPDHGRPESATPIIRMI
|||.. ..| | .. .| |. | . ..| . |. ||.. | . |. . ..| | .| . .. . | |... |.. . .|. .
Wrmvfqekivsvvilvgeeelkk.tlselfpkksgdykeygkmfvNnrkVekaeeektryviEvlPegcs.nsvlanvyvltnWkqkkvpvkyaelikta
EMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPdklDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTN
. .. | . .| |.|| |.... | . | |. | . ||...|.|||..|..|.|||..|.|.. .... .|.
akvfakkikadentvivSknGaGRagafltlavaveklqkgkep...nikeivksiRsqRpravdslkQyvslyialllyikkkvtk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 31-298 | 5.8e-73 | 240.6 | In-house | 32-294 (330) | alignment | ||
Range on Protein: 31-298
Range on HMM: 32-294/330.0
ATFNKEFQALKMEsqryKDQNTFpaESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQ
| .||.|| . |.|. | .. ||.|||. .|||....|| | ..|||| |||||| .|.| ..||||||. .||.||||||| ..
klfreefnalPag....piqatl..elaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqk
IEIVIMACREVEMAKPKCQCYWPQVGeSAMYGAIQVTTDHEENVS----NDFIIRQLTAECQ-GEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHR
..| | . ||. |||. | . || |.|. ..|. . .|...||. ... .....||||.|.||| | | . ...... .. .
sativmltelkerkeekcaqywPdeG.lvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkkln
KRHDIPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
... | .||||| ||||| |..| ..| . |.||| .|...|.||| |||.. ||.|.| .. |
qqsagpivvhcsaGvGrtGtfivld...avlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 31-305 | 5.5e-51 | 168.2 | In-house | 20-242 (392) | alignment | ||
Range on Protein: 31-305
Range on HMM: 20-242/392.0
ATFNKEFQALkmesqryKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQ
| | .||. | . . .| ..|...|.||||.|.|||.. .||.| |. . |||.|| ||.. | . |||.||| . ...|||||.. ..
alffeefhdl.......pgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqen
IEIVIMACREVEMAkpkcqcywpqvgesamygaiqvttdheenvsndfiirqltaecQG-EKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHD
. ..| . | .| ... . |||.| |||.. |. .. ....|. . . ..
vttiamvtklkegd...........................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqyt
IPFAIHCSAGCGRTGTIIAIDFARTmLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTN
|. |||||| |||| .|.|| . ||| .||| .| ..|..|| |||. .|| |.| |..| . |
hpliihcsagvgrtgvvisidsvva.hakkt..rmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntl
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 32-297 | 9.1e-42 | 138.1 | In-house | 10-275 (307) | alignment | ||
Range on Protein: 32-297
Range on HMM: 10-275/307.0
TFNKEFQALKMESQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLhKIEGVeGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQI
|..| |||. | . ... | .|||..|. . .|. . |..|. |||| |||. .|.||||| |. .|| |. ...
tldkgvqalvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivv.kfdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekv
EIVIMACREVEMAKPKCQCYWPQV-GESAMYGA----IQVTTDHEENVSN--DFI-IRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFRE
| ||| |. .|.|| ||. ||| . |. ..| | |. .... |.| . .| . .. . |... .. |||.| |. | ..| |
esvimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry
HRKrhdiPFAIHCSAGCGRTGTIIAIDFARTMLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE
.. | .||||| ||.|||.|| . . .|. . |. .|...|.||. .|. ||.... ..|
dtn....pvvvhcsaGvGrsGtivaislvqdkmiaGi..nckdmkklveelrsqrhyaiqteaqylylhrvlle
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 32-300 | 2.8e-37 | 123.1 | In-house | 16-288 (305) | alignment | ||
Range on Protein: 32-300
Range on HMM: 16-288/305.0
TFNKEFQALKMESQRYKDQNTFP-AESGQNPVNKKKNRFKDILPFEYTRVQLhkiEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQ
|..| . |. | . | | | .. .. ...|||.||. .. ||.| || .|| |||. | .| .| || .| ||| | . ..
tlekgpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdk
IEIVIMACREVEMAKPKCQCYWPQVGESAMY---GAIQVTTDHEENV--------SNDFIIRQLTAECQGEK-QVIRQFHYTAWPDHGRPESATPIIRMI
.| ..| | .| ||. |.. . . . ... | | . . .|. | ||| . . ..|. ||| | | . . |. ..
veaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailell
EMFREHRkrhdIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDKLDvfSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQ
| | . | ..||||| ||||... ... |. | .. | |.|..|.|| .|. .||.||. |.. ..
ekarpsk....gpivvhcsagigrtgsvvmleyildqllagqiiedtd..kilqkireqrnnsiqtdaqylfvhqvilnyfr
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 33-305 | 1e-86 | 286.3 | In-house | 15-283 (297) | alignment | ||
Range on Protein: 33-305
Range on HMM: 15-283/297.0
FNKEFQALkmesqrYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLhkieGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIE
. |||. | .. .. .. . ...| |..|||.|||||...|||.| . ||||||||.|..|.| . ..||.|||||.||.|||||.| ....
llkefeel......lpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvt
IVIMACREVEMAKPKCQCYWPQV-GESAMYGAIQVTTDHEENV-SNDFIIRQLTAEC--QGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKR-
...| ...||. ..||. ||| ||| || ..||. ..| | ..|...|.|. .. ||. ....|||| ||||| |||.......||..|...|
vIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkll
-HDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTN
. | .|||||.||.||.||.| . .| .|.. ..|....|...|.||| .|| |.||.|.|.|. ||.. ||
psggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltk
|
|||||||||
DSPc_SM00195 | 33-299 | 6.7e-86 | 283.2 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 33-299
Range on HMM: 2-262/263.0
FNKEFQALKMESQRYkdqntfPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIE
...||. |... . . .... . ||.|||.|.|||.. |||.|.|.|. |||||||||||.|.. . .|||.|||||.||.|||||.| ....
lkeefekleestspk......etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvk
IVIMACREVEMAKPKCQCYWPQV-GESAMYGAIQVTTDHEENVSNDFIIRQLTAECQG--EKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHD
|..| ..|.| | ||. |||. |.. .| |.|.. ..|......|.|.|. . .| |.. ..|..|..||||| |.|................. .
iivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstss
IPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIpdkLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
| .|||||.|||||...||.. | ... .|.|.||...||||| ||| |.|| |.|.||.|..
gpivVhCsaGvgRtgtfvtidiilskleeekk...vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 33-299 | 6.7e-86 | 283.2 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 33-299
Range on HMM: 2-262/263.0
FNKEFQALKMESQRYkdqntfPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIE
...||. |... . . .... . ||.|||.|.|||.. |||.|.|.|. |||||||||||.|.. . .|||.|||||.||.|||||.| ....
lkeefekleestspk......etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvk
IVIMACREVEMAKPKCQCYWPQV-GESAMYGAIQVTTDHEENVSNDFIIRQLTAECQG--EKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHD
|..| ..|.| | ||. |||. |.. .| |.|.. ..|......|.|.|. . .| |.. ..|..|..||||| |.|................. .
iivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstss
IPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIpdkLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
| .|||||.|||||...||.. | ... .|.|.||...||||| ||| |.|| |.|.||.|..
gpivVhCsaGvgRtgtfvtidiilskleeekk...vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 34-302 | 4.9e-89 | 293.7 | In-house | 3-277 (284) | alignment | ||
Range on Protein: 34-302
Range on HMM: 3-277/284.0
NKEFQALKMESQRykdqNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGV-EGSDYINANYIQGP-----DGNVEYIAAQGPLPHTVNDFWRMIW
.||..| . ... . .. | |..|||.|||||....|| |. ..| |.||||||.|..|. . . ..||.|||||.||.|||||.|
eeefeellsltvk....lllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvw
YHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGAIQVTTDHEENvSNDFIIRQLTAEC---QGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREH
.......| ...||. . || |||. ||. .|| ..||. .||. .|...| |. .. || ...||||.||||| |.|.......... ||.
eqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseev.kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrel
RK--RHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
.. . | ..|||||.|||||.||.| . ..|.|. .. ..||...|...|.||| ||| |.||.|||.|..|...
lenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 34-298 | 8.5e-85 | 279.8 | In-house | 16-276 (278) | alignment | ||
Range on Protein: 34-298
Range on HMM: 16-276/278.0
NKEFQALKMESQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEI
.....|. | ... ...... . .. | ||.|||.|||||....||.|. ..|...||||||.|. |.. . ..||.|||||.||.|||||.| .....
lnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvtt
VIMACREVEMAKPKCQCYWPqvGESAMYGAIQVTTDHEENvSNDFIIRQLTAE--CQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIP
..| ...||. ..||. ||| |.| || ..||. || .|...|.|. . ||.. ....||..||||| ||| ..........||... . |
ivmLtelvelgrvkcaqYwp..ggsltygdftvtllkeeh.lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngp
FAIHCSAGCGRTGTIIAIDFARTMLIKKTipdKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
..|||||.|||||.||.. . ..| | ..|....|...|.||| .|| ..||.|.|.|. |.
vlVHCsaGvgRTGtfialyllleqlekeg...gvdleeavkelreqRpgavqtpsqyrflyealley
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 34-296 | 6.1e-39 | 128.5 | In-house | 27-286 (305) | alignment | ||
Range on Protein: 34-296
Range on HMM: 27-286/305.0
NKEFQALKMESQRYKDQNTFPAESGQNpVNKKKNRFKDILPFEYTRVQLHKIEgveGSDYINANYIQGPD-GNVEYIAAQGPLPHTVNDFWRMIWYHQIE
.||. | .. |..| |. . ... |||..|. . . |.|.| |||| |||. | . .|.||||| .|...|| |. ...|
reefrglakytrpdmtqvafnanqsad.iaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkve
IVIMACREVEMAKPKCQCYWPQ-VGESA-MYGAIQV---TTDHEENVSNDFIIRQLTAECQG-EKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRk
..| |. ||. | || ||| || . . | | . . . .. | | | .| .|....| ||| | | . .. | .
qivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsairgsk.
rhdIPFAIHCSAGCGRTGTIIAIDFARTMLI-KKTIPDkldVFSIVQQMRKQRPAMVQALDQYVFVYMAIV
.| .||||| ||||||.||.. . .| | . .|. .| || .|. ||.|.. ..
...vpivvhcsagigrtgtivaieyilekiaenkpcpp...mpelvkalrdqrafsiqndvqylfihrvml
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 35-311 | 3e-90 | 298.0 | In-house | 15-288 (317) | alignment | ||
Range on Protein: 35-311
Range on HMM: 15-288/317.0
KEFQALKMESQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIV
. |.||. | ... ... . . .. |.||.|||..||||....||.|. ..|...||||||.|..||. . ..||.|||||.||.|||||.| ......
sdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvi
IMACREVEMAKPKCQCYWPQvGESAMYGAIQVTTDHEENvSNDFIIRQLTAE--CQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPF
.| ....|. ..||. |||. ||. || ..||. || .....|.|. | .|. ...||||.||||| |.| .......|. ||...... |
vmLteleelgrekcaqYwpl.getltygdftvtllseee.lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavrealedpggpv
AIHCSAGCGRTGTIIAIDFARTMLIKKTipdKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTNVPQLPP
..|||||.|||||.||.. . .| |. ..||...|...|.||| .|| ..||.|.|.|. |... || .| ..
lVHCsaGvgRtGtfiaaylmleqlekeg...gvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepasel
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 35-299 | 4.1e-58 | 191.4 | In-house | 6-271 (290) | alignment | ||
Range on Protein: 35-299
Range on HMM: 6-271/290.0
KEFQALKMESQryKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGvegsDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIV
. .... .. . |. . ||... ..| |...||..|. |....|..|.. . |||||. .. .. . .|| .|||||.||. ||.|.| .. |
rlykeiyldir..keasdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskav
IMACREVEMAKPKCQCYWPQVGE--SAMYG--AIQVTTdHEENVSNDFIIRQLTAEC--QGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHR--K
.| . || . ||. |||| | . .. ..|. .|.... ...|.| | | ..| .||||.||| | ||| . .... || .
vmlnkvvekeqikcaqywPqgeeekellledtklkvkl.iseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGsls
RHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
.. | |||||| ||.||.. .| . || . .|. . ..||.| ..|. || | |.||.| .
sdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGa
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 37-303 | 4.7e-84 | 277.6 | In-house | 31-293 (297) | alignment | ||
Range on Protein: 37-303
Range on HMM: 31-293/297.0
FQALKMESQRYKDQNTfPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGV-EGSDYINANYIQGPDG-NVEYIAAQGPLPHTVNDFWRMIWYHQIEIV
.. |..| ....... . . .. |.||.|||.|||||....||.|. ..|| ..||||||.|..|.| . ..||.|||||.||.|||||.| ......
ktllllefeellslkp.dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvi
IMACREVEMAKpKCQCYWPQVGEsaMYGAIQVTTDHEENvSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKR--HDIPF
.| ...||. . ||. |||. |. .|| ..||. .| .....|.|. . || ...|.|| ||||| |.|.. .....|. ||.... . |
vmLtklvelgr.kcaqywpeegg..tygdftvtllkveh.ldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpv
AIHCSAGCGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSL
..|||||.|||||.||.. . ..| |. ..||...|...|.||| .|| ..||.|.|.|..||... |
lVHCsaGvgRtGtfiaaylmleqleke...ggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 38-302 | 1.6e-60 | 199.7 | In-house | 26-287 (297) | alignment | ||
Range on Protein: 38-302
Range on HMM: 26-287/297.0
QALKMESQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGnvEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMA
. . | . |..|. .. || .|.|.|.|||.. ||.|. .. |||.|| ...| ..|. | | . ||.|||.|.. .|. ...|
dvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivml
CREVEMAKpKCQCYWPQVGESAmYGAIQVTTDHEENVsNDFIIRQLTAECQG--EKQVIRQFHYTAWPDHGRPE--SATPIIRMIEMF-REHRKRHDIPF
. | | ||. ||.. | .. .| . |.. .. . || |.|. . . ..|..|.... |||. .. ||. .. .|. .. .. . |
nddnerdk.kcaryWsdkgvtt.fGdvsvvllsvser.eGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPl
AIHCSAGCGRTGTIIAIDFARTMlIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
.||.|| |||| ...|| . .|.. ...|.| .|...|..|| .||. .|| ||| |..| .
lvhclaGvGrtgvlltidsvvae.akre..kevdifglvkklrqerpylvqtkeqykfvyvavleallse
|
|||||||||
subfamily_eak_pd | Subfamily eak | 39-216 | 1.7e-11 | 38.1 | In-house | 28-198 (332) | alignment | ||
Range on Protein: 39-216
Range on HMM: 28-198/332.0
ALKMESQRYKDQNTFPAESGQNPVNKKKNrFKDILPFEYTRVQLHKIEgVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMAC
... .. . |. . .. . ..| .|.|... |.| . |||| .. .. .|| . . | ||.|. . ...
rinivadlddyqrllsisetarleavnrn.vvkivpydrylvrltssq.lnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqll
REVEMAKPKCQCYWPQVG-ESAMYGAIQVTTDHEeNVSNDFIIRQLTAECQGEKQVIRQFHYtawpdHGRPESATPIIR
.||. | . |.|. . | .| ..|.. . | . |.| . | . ... .| | ..|...
edvelkleksdkyfpdktreelkfGildverkef.vkrniletrllelskGnethrvlhykv.....fGwtettlpkye
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 40-300 | 7e-45 | 148.0 | In-house | 17-294 (301) | alignment | ||
Range on Protein: 40-300
Range on HMM: 17-294/301.0
LKMESQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEG--VEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMA
.. . .. |... ... | . ||. ||||.| ... |. |.. . . .||||.||.| . ..||||||. .|. ||||.|| .. ..|
feeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmv
CREVEMAKPKCQCYWPQ-VGESAMYGAIQVTTDhEENVSNDFIIRQLTAECQG-----------------EKQVIRQFHYTAWPDHGR-PESATPIIRMI
. . | .| ||. |||. || .| ..|| .|.| ||.||||. | . . . |.. | ||..| .| .| . .
tnlkegtkskceqywpnseaeseefgpftvtlv.neqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqvid
EMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIpdkLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQ
.. .| | .|||.. .|.|. .... . .. ||| ... .|...| .|. |.||...| .| . .|
dvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegV...VdvfqvtkavrrskpgaVtTLeqytsiydvidmylq
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 42-306 | 1e-66 | 220.1 | In-house | 19-283 (515) | alignment | ||
Range on Protein: 42-306
Range on HMM: 19-283/515.0
MESQRYKD---QNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMAC
. |. ..| | .| |. .| ||||.|.|||.. .||.| |. |||.|| ||.. | . |||.|||.. .|.||||... ... ..|
lfseefhdlpgpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvt
REVEMAKPKCQCYWPQ-VGESAMYGAIQVTTDHEENvSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCS
. | | || |||. |.| .| |.| . | . |.|.|| . . . . |||.| |||.| |. .. ....| . . . |. ||||
klkegdkikcgkyWPdkpgdsvkfGsikvelvslea.ctggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcs
AGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTNV
|| |||| .|.|| .. . . .||| .|...|..|| .||. .|| |.| |. | . | .
aGvGrtGvvisid...svvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntli
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 43-300 | 3.2e-65 | 215.0 | In-house | 24-278 (315) | alignment | ||
Range on Protein: 43-300
Range on HMM: 24-278/315.0
ESQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVE
| . | .... ......| ||||.|.|||.. .||.| |. |||||| ||.. | . |||.||||. .|.|||||.. ... ..| |
efhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqe
MAKPKCQCYWPQ-VGESAMYGAIQVTTDHEENvSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCG
| ||. |||. ..|. .|.|.|.. | | ..|.|. |.. . ||..| |||.| .. .. ....| . ..... .. .||||| |
gdkikcrqywPdrkadsvefGsikvellslea.dtdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvG
RTGTIIAIDFARTmLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQ
||| .|.|| ||.| . .||| .|...|..|| .||. ..| |.| |. | ..
rtGvvisidevva.qikrt..rsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 44-301 | 1.1e-67 | 222.9 | In-house | 22-277 (280) | alignment | ||
Range on Protein: 44-301
Range on HMM: 22-277/280.0
SQRYKDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEgvEgsDYINANYIQG--PD--GNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACR
| |. .. . . | | .|||..||||.. |||.|.. | |||||||.. | . |||.||||..|..|||.|.| .......|
eqlyrkkpglaisaarkpenlsknryrdilpydatrvklkese..t..dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmltt
EVEMAKPKCQCYWPQVGESAMYGAIQVTTDHEeNVSNDFIIRQLTAECQG--EKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCS
|| . || |||. ... || ..|. .| . .. ...|.|. . . |.. | |. |.|||||| |.... .....| |. |. .. | .|||
lverGrvkChqyWPetedeleygefsvkceke.detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCs
AGCGRTGTIIAIDFARTmLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
|| |||| .|... | . || .. ... . ||..|| || ..||. .|| || ||... ..
aGigrtGvlilletala.lieaa..epvypldivrtmrdqramlvqtasqykfvCeailkvyee
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 46-298 | 1.5e-46 | 153.6 | In-house | 19-265 (283) | alignment | ||
Range on Protein: 46-298
Range on HMM: 19-265/283.0
RYKDQNTFPAESGQnpvNKKKNRFKDILPFEYTRVQLHKIEGvegsDYINANYIQ---GPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVE
|... | . . ||.|||...|.| . ||.|. ||||| .| . . .||.||.|| .|| |||.|.. ..| ..| . |
svpdldadiasade...nkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqe
MAKPKCQCYWPQVGeSAMYGAIQVTTdHEENVSNDFIIRQLTAECQ---GEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAG
. || |||. | | || || ..| || |||..|. . .. .. . . | . | .... . .. .. | .|||.|
dlrikCsqyWPkrG.sedyGeftvtl.rkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstg
CGRTGTIIAIDFARTMLIKKTIpdkLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
|||.. ||. . . ... .|||..|. ||.||. .||.|||| .|. ...|
iGrtavfiaasasvkdaltesv...vdvfavvkimreqrmmavqtldqyklvhelvleq
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 47-212 | 2.7e-06 | 20.4 | In-house | 14-159 (169) | alignment | ||
Range on Protein: 47-212
Range on HMM: 14-159/169.0
YKDQNTFPAESGqnpVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINAnyiqgpdgnveyiaaqgplphtvndfwRMIWYHQIEIVIMAC--REVEMA
. | | || .|. ||| | .|||.|... ||||||| |||| . .... . .
tieynnfmaelt...cnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddknnf
KPKCQCY--WPQVGESAMY-GAIQVTTDHEENVSND----FIIRQLTAECQGEKQ-VIRQFHYTAWPDHGRPESAT
|. . | | | | .. | ||. . .. | . . . . . .. .||..||. | |.|
wpekedyqlhpavilgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpqspv
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 48-212 | 2.7e-06 | 20.3 | In-house | 14-158 (169) | alignment | ||
Range on Protein: 48-212
Range on HMM: 14-158/169.0
KDQNTFPAESGqnpVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINAnyiqgpdgnveyiaaqgplphtvndfwRMIWYHQIEIVIMAC--REVEMAK
. | | || .|. ||| | .|||.|... ||||||| |||| . .... . .
ieynnfmaelt...cnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddknnfw
PKCQCY--WPQVGESAMY-GAIQVTTDHEE-NVS---NDFIIRQLTAECQGEKQV-IRQFHYTAWPDHGRPESAT
|. . | | | | .. | ||. . |.| | . . . . . . .. .||..||. | |.|
pekedyqlhpavilGewytdslyvrtdkvhpntsgveglfevslvihsydddvteqlsllhystwpqngvpqspv
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 48-135 | 2.9e-06 | 21.0 | In-house | 19-105 (332) | alignment | ||
Range on Protein: 48-135
Range on HMM: 19-105/332.0
KDQNTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEgsDYINANYIQGPDGNVEYIAAQGPLP-HTVNDFWRMIWYHQIEIVI
|.| . | || . |...||.| .| . |. ||....| . || || |. || ||||. .. ...
tsamtypntydkflnnmdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmil
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 51-300 | 2.8e-63 | 208.8 | In-house | 37-280 (315) | alignment | ||
Range on Protein: 51-300
Range on HMM: 37-280/315.0
NTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQC
. .| . .. ||.|||. .|.... .|||| .| ..|||.|||.|.| . . |||||||.. .|.||||... ..| ..| || | |..
qlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaek
YWPQVgeSAMYGAIQVTTDHEEnVSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAID
||| .|| | || || | ... .| |. . . . . |.|||.||| | |....|.. .| . |.. . .||||| ||||| |..|
ywpdk..kviyGkitvtrksee.vnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitld
farTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQ
..| . . . .||. .....|..| |||...|| |.| |..| .
...avldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfv
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 51-301 | 8.1e-38 | 125.1 | In-house | 30-274 (288) | alignment | ||
Range on Protein: 51-301
Range on HMM: 30-274/288.0
NTFPAESGQNPV-NKKKNRFKDILPFEYTRVQLHkiegVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQ
| . .. .. . | ..|.... ..|||.|. . ||.|| . . | || || |.. .|.|. ..| ..| |. .| |.| .
neasidiidsfianptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksa
CYWP-QVGESAMYGAI-QVTTDHEENVSNDFIIRQLTAECQGEKQV-IRQFHYTAWPDHGRPESATPIIRMIEMFREHRKrhdiPFAIHCSAGCGRTGTI
|.| ..||.| .| . .|. .. ... . | . .||..| ... |. |.|.| ||. . .|..|......| | .|.||| |||||.
eyfPsklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqk....PivvhssaGvGrtgtl
IAIDFARTMLikkTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIV-ELVQQ
| | .| ..| ..| | . |.....|..| .|. ||..|. . ||...
ililialesl...rlddflgirsllaklreerfkaiqtemqylyvhrcvleelllk
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 51-102 | 2.6e-09 | 30.9 | In-house | 35-86 (440) | alignment | ||
Range on Protein: 51-102
Range on HMM: 35-86/440.0
NTFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGP
. |.. | || |||...|| ....|| |....|| |||||| ||.|
lsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingi
|
|||||||||
subfamily_egg_pd | Subfamily egg | 52-301 | 3.1e-31 | 103.2 | In-house | 29-272 (307) | alignment | ||
Range on Protein: 52-301
Range on HMM: 29-272/307.0
TFPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMakPKCQCY
. . . |..| | | . ...||.|. .| |.| ||...| |.| || || ||.|||||.. ... ..| .| .|. |
eislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyy
WPQV-GESAMY--GAIQVTTDHEEN-VSNDFIIRQLTAecQGEKqvIRQFHYTAWpdHGRPESATPIIRMIEMFREHRKRhDIPFAIHCSAGCGRTGTII
||. .|... |...... . .. | . .| | . . . | | . .. . ....| |. | ... |. ...|..
wpkaesdslvtvpGslrienlkvdskadplfrvtklkl..vGgd..deerflehw..qgdvnnssdvysplrvlrklrnl.skpvvvqdilGvskaatlv
AIDFARTMLIKKTIpDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
||. | |.. | | | |. .|..|. |.. .|.||| .. ....
aieiallsllrGpi.tkslvlravvflrlrrrlsvesvllylfvyrlvlfffrd
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 53-307 | 5.2e-64 | 211.4 | In-house | 38-296 (325) | alignment | ||
Range on Protein: 53-307
Range on HMM: 38-296/325.0
FPAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQiEIVIMACREVEMAKPKCQCYW
. | ||.|||||...... .|| | . ||||||.|.. . ..||| ||..|.||.||.. . |.. |.. | .| ||
iakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvvlneldlgkdrcavyw
PQV-GESAMYGAIQVTTDHEENVsNDFIIRQLTA--ECQGEKQVIRQFHYTAWPDHGRP---ESATPIIRMIEMFREHRK---RHDIPFAIHCSAGCGRT
|. |.| .|...| |.. |.. |.| .|| . ..||.. .|.| | . . .|..... | . . |. .||||| |||
pkemgksktfGglevklrtieei.sdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrt
GTIIAIDFARTMLIKKTipdKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTNVP
|. |.. | .|... ..|.| |...||.||.||.. |||...| |.|| . . |.||
Gvfislysalakviees...rvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvp
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 54-300 | 7.9e-69 | 226.9 | In-house | 28-270 (273) | alignment | ||
Range on Protein: 54-300
Range on HMM: 28-270/273.0
PAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGvegsdYINANYIQGPDG--NVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCY
.|.|.. ||.|||....||.. |||.| . | ||||..|. | | . ||||.|||||.||.|||.|.| . |...| |.| | ||. |
tcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchry
WPQVGESAM--YGAIQVTTDHEENVSnDFIIRQLTAEC--QGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKrHDIPFAIHCSAGCGRTGTII
||. .. . .. ..|. . .. . .| .|.|. . || . . ......||||| | ||....... |. .. . | ..||||| ||.||.|
wPesknkklkvsnrlevellkvqkld.gfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt.dagPivvhcsaGiGrsGtli
AIDFARTMLIKKTipdKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQ
.|| . .. ... ..|| ||...|.|| ..||. |||.||| ||.|...
tidvvlglierdk...efdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 54-302 | 5.1e-54 | 178.3 | In-house | 40-299 (300) | alignment | ||
Range on Protein: 54-302
Range on HMM: 40-299/300.0
PAESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVeGSDYINANYIQGPDG--NVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCY
.....|.|..||||||.||.| .||.| . ..|||| |. . | . .||.|||||..||.|||.|.| .......| .| | | |. |
llstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfky
WPQVG---ESAMYGAIQVTTDHEENvSNDFIIRQLTAE--CQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRH---------DIPFAIHCS
.|. . ... .| .||| |. |. .| ..|. . .|.. . . || ||||| || .. . .|... |.. . | .|||
fPkleskkktvefgkfkvttkfsed.sdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCs
AGCGRTGTIIAIDFartMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
|| |||| .| |. .. ...|. ......|.|| .||.| || ||| .... ...|
aGvGrtGvlilsdl...liatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylkns
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 54-248 | 2.6e-42 | 140.0 | In-house | 36-248 (418) | alignment | ||
Range on Protein: 54-248
Range on HMM: 36-248/418.0
PAE--SGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGnVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCY
|.| |.. | |||. .||| ..|||||.||. |||||||||||.| ..|..||||| |. |||||.| . |..| || | .. ||. |
psetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdry
WP-QVGE--SAMYGAIQ-V-TTDHE------ENVSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRK------RHDIPFAI
|| |.| ..|| . | | .. . | |.. .|| . | |..| |||| |. . |. ... .... ...| .
wpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiiv
HCSAGCGRTGTIIA
||||| |||||. .
hcsagvgrtgtfct
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 55-312 | 3e-66 | 218.4 | In-house | 35-290 (314) | alignment | ||
Range on Protein: 55-312
Range on HMM: 35-290/314.0
AESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQ
.. .. |..|||..|||... .||.|. |.| ||||||..| . ..|..||||..||.||||... .. ..| || .. || |||.
wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPe
VGESamYGAIQVTTDhEENVSNDFIIRQLTAEC----QGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAID
.| || |.|. | .. .....| .. | | |....|||....||||. | ||| ..... .... .. . .|||||.||||| ||||
dtev..ygdikvelv.etellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaid
FARTMLIKKTIpdkLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTNVPQLPPR
|. .. . .||| .|...|.... ||.. .||.|.| .|.| . | .| .
ivldmieregv...vdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefk
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 55-301 | 3e-65 | 215.2 | In-house | 34-292 (297) | alignment | ||
Range on Protein: 55-301
Range on HMM: 34-292/297.0
AESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWP-
.. . ..| .|||..|.| .. |||.| |... | |||||||...| . .||.||||..||.|||||.| ... ...|. | ||. . ||. |||
flasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpl
QVGESAMYGAIQVTTdHEENVSNDFIIRQLTAE--CQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHR-------------KRHDIPFAIHCSA
. ..|| .| ..|.. | ....|. .|.|... ..|.. . | ...|||.| |.||. .. ..|. ||.. . .. | .||||
eeessaefgdlsvsn.veveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsa
GCGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
| ||||| |..|.. . | .. ...||. |...|.|| ..| .||.| |.|..| ..
GiGrtGtfitldiclsrleev...gtvdvvetvkllrtqrafsiqtpeqyefcylavleyale
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 56-300 | 3e-76 | 251.7 | In-house | 26-273 (278) | alignment | ||
Range on Protein: 56-300
Range on HMM: 26-273/278.0
ESGQNPVNKKKNRFKDILPFEYTRVQlhkiegvegsDYINANYIQGPdgNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQv
. .. . |..|||.|||||....|| |||||.||.|. . ..||.|||||.||.|||||.| ..|....|....||... || |||
tpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpe.
GESAMYGAIQVTTDHEENVsNDFIIRQLTAE------CQGEKQVIRQFHYTAWPDHGRPESA--TPIIRMIEMFREHRKR-------------HDIPFAI
|.| || ..||. ||.. .|...| |. . .|. ....||. ||||| |.. .......|. ||..|. .. | ..
ggsltygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlV
HCSAGCGRTGTIIAIDFARTMLikktiPDKLDVFSIVQQMRKQRPA-MVQALDQYVFVYMAIVELVQ
|||||.|||||..|.. ...| ....|....|...|.||| .|| |.||.|.|....||..
HCsaGvgRtGtlvaaylmlell.....eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 56-301 | 4e-67 | 221.2 | In-house | 21-270 (274) | alignment | ||
Range on Protein: 56-301
Range on HMM: 21-270/274.0
ESGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVE-GSDYINANYIQGPDGNVE-YIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWP
| . . ...|||.|.||| | .|| |.. .. . |.|||||||.|.|.. . |.|.|||||.||.||||||.........| . |. . ||. |.|
eeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfP
QVGES---AMYGAIQVTTDHEeNVSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDI---PFAIHCSAGCGRTGTII
. . || ....... . ||. .|.|. . . ... . . ||.|||| |..|........ .| |.... | .||||| |||| |
daedyeiserygdveikveki.verndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfi
AIDFARTMLIKKTipdKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
||. | | ... ..||..|| ..| .| |||. .|| ... |... ...
aisiavrqlreei...vvdvlkivcnlrldrGGmvqtseqyelihralclylkr
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 57-299 | 1.3e-78 | 259.4 | In-house | 5-246 (249) | alignment | ||
Range on Protein: 57-299
Range on HMM: 5-246/249.0
SGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQvG
.. |.||.|||..||||....||.|. ..|...||||||.|| |.. . ..||.|||||.||.|||||.| ..|....|....||. . ||. |||. |
vallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.g
ESAMYGAIQVTTDHEENvSNDFIIRQLTAE--CQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKR--HDIPFAIHCSAGCGRTGTIIAIDFA
.| || ..||. ..| ..|...|.|. . ||. .....|| ||||| |.| .....||. |..... . | ..|||||.|||||.||.. .
gsleygdftvtllsvev.kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylm
RTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
..| |. ..|....|...|.||| .|| ..||.|.|.|. ||.
leqleke...lgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 57-299 | 1.1e-75 | 249.5 | In-house | 3-243 (245) | alignment | ||
Range on Protein: 57-299
Range on HMM: 3-243/245.0
SGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQvG
... |.||.|||..||||...|||.| ..| ..||||||.|. |.. . .||.|||||.||.|||||.| ..|....| ..|.|. ..||. |||. |
vallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.g
ESAMYGAIQVTTDHEENvSNDFIIRQLTAE--CQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRK-RHDIPFAIHCSAGCGRTGTIIAIDFAR
|| || ..||. ||. .|...|.|. . .|.. ....||. ||||| |.. .....|. |.... . | ..|||||.|||||.||.. .
esltygdftvtllseeh.lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylml
TMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
..| | .......|...|.||| .|| ..||.|.|.|. ||.
eqleke...lgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 57-299 | 1.4e-49 | 163.3 | In-house | 36-290 (296) | alignment | ||
Range on Protein: 57-299
Range on HMM: 36-290/296.0
SGQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKpKCQCYWPQVG
| . |..||| ...|..|.|| |.|..| | |||||| |... . ||| ..| .||..|||... ..|. |.. ... ..|| ... |||. .
gglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks
eSAMYGAIQVTTDHEENVSN----DFIIRQL-------TAECQGEKQVIRQFHYTAWPD-HGRPESATPIIRMIEMFREHRKRH-----DIPFAIHCSAG
. || | | . .|.. .| | . . ... . |. ....|..| |. . | |.. .| .... | |.. | ...| |
.keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdG
CGRTGTIIAIDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
.|.| .||| . ...|. ...||| |...|..|| .|. ..| ..| . | |
asRsGvylaidanlelveke...eevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 58-298 | 1.5e-73 | 242.6 | In-house | 5-241 (243) | alignment | ||
Range on Protein: 58-298
Range on HMM: 5-241/243.0
GQNPVNKKKNRFKDILPFEYTRVQLhkiegvEGSDYINANYIQGPDGnveYIAAQGPLPHTVND----FWRMIWYHQIEIVIMACREVEMAKPKCQCYWP
.. |.|..|||..||||....|| | |||||||||.|..... .|| |||||.||.| ||||.| ..|....| ...||. . || |||
allpenlsknrysdilpydhsrvkl......egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp
qvgESAMYGAIQVTTDHEENVsNDFIIRQLTAEC---QGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREH--------RKRHDIPFAIHCSAGCGR
.. .|| ..||. .||. .|...| |. |. ..... ....||..||||| |.| ......... ||. .. | ..|||||.||
...gevtygdftvtllseehl.ddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgR
TGTIIAIDFARTMLikktipdKLDVFSIVQQMRKQRPA-MVQALDQYVFVYMAIVEL
|||.||.. ..| ..|....|...|.||| .|| ..||.|.|.|. ||
tGtliaaylmllll.......gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 58-300 | 7.2e-68 | 223.5 | In-house | 4-243 (250) | alignment | ||
Range on Protein: 58-300
Range on HMM: 4-243/250.0
GQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPkCQCYWPqVGE
...| ||.|||. ||.... .|| |.| .| . |||||| ...| |.. .||.||||..|..|||||.. .... ..| .|. | .. ||| | .
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywP.vek
SAMYGAIQVTTdHEENVSNDFIIRQLT--AECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKR-HDIPFAIHCSAGCGRTGTIIAIDfarT
. || ..|. ..... |...|.| . . .....||.|...||| | || || .. ... . ... .. | ..|||| ||.|. |||| .
aekyGdvtvsl.lskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaid...a
MLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQ
.| . . ..||| .....||.|| .|..|.||||||..| . ..
vlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 58-297 | 3.6e-51 | 168.6 | In-house | 3-239 (239) | alignment | ||
Range on Protein: 58-297
Range on HMM: 3-239/239.0
GQNPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNV-EYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVg
.. ||| |||. .|. ....|| | |. ||||||.|.. ||. |||.|| . . |||||.| . ...| .| | ||. |||.
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds.
eSAMYGAIQVTTDHEEnVSNDFIIRQLTA--ECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDfarT
.. | ..|| . | | |.||| . | |.. . |.|.| |||.| |. || .. . . |. |||||| ||||... || .
.tskycnlrvtlrkte.vfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvid...a
MLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE
|| . .|.| |. .|..|| |||. .||||...|..|
mlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 58-300 | 3.1e-44 | 147.3 | In-house | 41-281 (314) | alignment | ||
Range on Protein: 58-300
Range on HMM: 41-281/314.0
GQNPVNKKKNRFKDILPFEyTRVQLhKIEGVEGSDYINANYIQGPdgnVEYIAAQGPLPHTVNDF----------WRMI--WYHQIEIVIM---------
.. ..|..|||..||||.. .||.| . ..|.|||||||.|. |. .||.||||..||.|| |||. . ... .. |
adlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlade
------------ACREVEMAkpkcqCYWPQVGESAMYgaiqvttdheE-------NvsndfiirqltaecqgeKQVIRQFHYTAWPDHGRPeSATPIIRM
.. . .... . | .. . ..... .||.. | . . ..
lsrLdaAlgKtpllildgng.....neptaadlellk..........eelydpelf.................erlgikylripvpDgsap.lledfdef
IEMFREHrkRHDIPFAIHCSAGCGRTGTIIAIDFARTMLikktipdKLDVFSIVQQMRKQRP-----AMVQALDQYVFVYMAIVELVQ
.|...|. . . |...||.||.||||| ..... | .... .....|..|| ... |.||.|...|. |...
lefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkll.......gvsleealedvrlkRpinpnpgfieqleqyefilealleylk
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 58-216 | 1.2e-34 | 114.5 | In-house | 28-188 (297) | alignment | ||
Range on Protein: 58-216
Range on HMM: 28-188/297.0
GQNPVNKKKNRFKDILPFEYTRVQLHKieGVEGSDYINANYIQGPDG--NVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQV
. . .|||..||| .. |||.| . .. ..|||||.|. || .. || ||||| ||.|||.... ... ...| .. | . || |||.|
akrnsslrknryrdilatddtrvkllr..viterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsv
GESAMyGAIQVTTDHEENVSNDF---IIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIR
. . | .| .. ..|..| |. .|. . |..|.| . .||||| | . |
vqerl.kagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvr
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 58-223 | 2.4e-27 | 90.4 | In-house | 22-192 (319) | alignment | ||
Range on Protein: 58-223
Range on HMM: 22-192/319.0
GQNPV-NKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPD-GNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQV
. || |.|.|. ...|. ||| |..| . . |..|.|..|.| . ||||| .| . ||||..| | ... .. | .| |.|
devPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtk
---GESAMYGAIQVTTDHEENVSNDFIIRQLTAECQGEKQ-VIRQFHYtAWPDHGRPESATPIIRMIEMFRE
. .|| |.|| . | . .| | . ..|. . . | |.. . | . ...| |. |.
etldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrs
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 59-297 | 1.2e-42 | 140.5 | In-house | 33-267 (281) | alignment | ||
Range on Protein: 59-297
Range on HMM: 33-267/281.0
QNPVNKKKNRFKDILPFEYTRVQLHK-IEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGE
..|||.||||. .| .. .||||. . . .||| ||||. | . || .||| | ||||||| . ..| |. .| . || |.|.
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnah
SAMYGAIQVTTDHEENVSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPiirMIEMFREHRKRHdIPFAIHCSAGCGRTGTIIAIDFARTM-L
.. . . | . .. .| .|| ..| .. . ||| |||. |....|. | | | |||||| ||.||..|.. |
cclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessev...mlkilrkirars.tppvihcsagvgrsgtlmaveialqsih
IKKTIPDkldVFSIVQQMR-KQRPAMVQALDQYVFVYMAIVE
. |.|| . || ..| | | ||.|.||.... ...
shftlpd...ikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 59-206 | 1e-13 | 45.5 | In-house | 92-234 (244) | alignment | ||
Range on Protein: 59-206
Range on HMM: 92-234/244.0
QNPVNKKKNRFKDILPFEYTRVQLHKieGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACrEVEMAkpkcQCYWPQVGES
|| | ||| |||.. || | | | | |||| .. ||| .| || | |||.|. ...... || . |||.
fnpnnswknregaglpfdfnrvplsk..gsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlg.sveee....deywpdsepl
AMYG-AIQVT-TDHEENVSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHG
| | || || .| .. .. . .| . | . || |
ewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwpsdg
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 60-297 | 4.2e-51 | 168.4 | In-house | 4-238 (239) | alignment | ||
Range on Protein: 60-297
Range on HMM: 4-238/239.0
NPVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNV-EYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVgeS
. ||| |||. .|. ....|| | |. ||||||.|.. ||. |||.|| . . |||||.| . ...| .| | ||. |||. .
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpds..t
AMYGAIQVTTDHEEnVSNDFIIRQLTA--ECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDfarTML
. | ..|| . | | |.||| . | |.. . |.|.| |||.| |. || .. . . |. |||||| ||||... || .||
skycnlrvtlrkte.vfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvid...aml
IKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE
. .|.| |. .|..|| |||. .||||...|..|
rqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 61-302 | 1.4e-69 | 229.1 | In-house | 18-267 (270) | alignment | ||
Range on Protein: 61-302
Range on HMM: 18-267/270.0
PVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGN-VEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGES-
.|| ||..|||| |||.|...| . . ||||||..| ||. .||||.|||| |...|||||| .. . ..|. .| . ||..|||. ..
argkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkek
--AMYGAIQVTTDHEENvSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESAT------PIIRMIEMFREHRKRHDI--PFAIHCSAGCGRTGTIIA
..| |.|.. .||. .. .|...|. | .||.. . |.|..||||| |... ...|.. |...|..| |. .||||| |||||.||
vkledgkikvlalseek.eegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlia
IDFARTMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
.|.| .| .. |.|| .|....||.|.|.|| .|| |.| |.|| ...
lDiavrlLeet...kkvdvlaiieelRkdRmalvqhpeqyeflykavveyaerr
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 61-310 | 1.6e-69 | 229.5 | In-house | 23-268 (284) | alignment | ||
Range on Protein: 61-310
Range on HMM: 23-268/284.0
PVNKKKNRFKDILPFEYTRVQLHKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACrevemaKPKCQCYWPQVGESaM
. || |||. .||.|. ..|.|... |.|.|||||| .|.| . |||.||||. |..||||||| ... ... | || |||. ..
dqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivi.k
YGAIQVTTDHEENvSNDFIIRQLTAECQ---GEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFR--EHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTM
.. .| | |. |.....|.. . ... |||||. |||.|.|.......|... | .....| . .|||||.||||. |..| .
eerfkvkvdsvee.seeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldr
LIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE--LVQQSLTNVPQLP
. .. ...||. .|...|.||. .|| | || |.|.|..| |. .| .|..|
mkee...kqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfp
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 61-102 | 1.2e-08 | 28.9 | In-house | 37-77 (244) | alignment | ||
Range on Protein: 61-102
Range on HMM: 37-77/244.0
PVNKKKNRFKDILPFEYTRVQLHKIeGVEGSDYINANYIQGP
.| |||. .||||. ||| | |||||||||||||
sanatknryinilpfdetrvilsss.kkegsdyinanyiqgs
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 62-298 | 6.9e-37 | 121.9 | In-house | 34-269 (285) | alignment | ||
Range on Protein: 62-298
Range on HMM: 34-269/285.0
VNKKKNRFKDILPFEYTRVQLHKIEgvegSDYINANYIQGPDG-NVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQ-VGESA
| ||. |. | ||| |.. . ||| |.... | . ||..||||| |..|||.||. .| |.| | .| || |.|. .||
anpdlnryadvrcieetrvvlknhd....rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevv
MYGAIQVT-TDHEENVSNDFIIRQLT----AECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHrKRHDIPFAIHCSAGCGRTGTIIAIDFART
.| ..| |. .|. |. || .. | . . . |||. || | |.| . . .. . .. | ..||||| ||| |.. ||.|
kfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkv.npkekpicvhcsagvgrtatfvgidyati
MLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
.... ..... ||..|| | ||. |..|.|. ..|
rimen...pniemldivremramrfqavqshmqflflyvvlmey
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 63-297 | 1.8e-80 | 265.1 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 63-297
Range on HMM: 1-235/235.0
NKKKNRFKDILPFEYTRVQLhkiEGVEG-SDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWP-QVGESAM
||||||.|||||.. |||.| .| || ||||||||..| . . ..||.||||..|..|||||.| .......| ....|. . ||. ||| . .|| .
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGAIQVTTD-HEENVSNDFIIRQLTAECQGEK---QVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTML
|| |.|.. .|.. ......|.|. . ..|. . ..|.|||.||||| |||.......|........ .. | .|||||.|||||..|.|.. .|
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
IKKTIpdkLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE
.. .||..||...||||| ||| |.||.|.|.||.|
eaeee...vdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 63-297 | 1.8e-80 | 265.1 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 63-297
Range on HMM: 1-235/235.0
NKKKNRFKDILPFEYTRVQLhkiEGVEG-SDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWP-QVGESAM
||||||.|||||.. |||.| .| || ||||||||..| . . ..||.||||..|..|||||.| .......| ....|. . ||. ||| . .|| .
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGAIQVTTD-HEENVSNDFIIRQLTAECQGEK---QVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTML
|| |.|.. .|.. ......|.|. . ..|. . ..|.|||.||||| |||.......|........ .. | .|||||.|||||..|.|.. .|
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleql
IKKTIpdkLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE
.. .||..||...||||| ||| |.||.|.|.||.|
eaeee...vdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 63-297 | 3.3e-52 | 172.1 | In-house | 3-237 (237) | alignment | ||
Range on Protein: 63-297
Range on HMM: 3-237/237.0
NKKKNRFKDILPFEYTRVQLHKIEGveGSDYINANYIQGPDGNV-EYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMY
|| |||. .| ....|| |. . |||||||.|..| || .|||||||| . .|||.|.| . ...| .| . || |||. . | |
nkiknrygnivaydhsrvvlkgags..gsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
GAIQVTTDHEENVSnDFIIRQLTAECQGEKQ---VIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKR--HDIPFAIHCSAGCGRTGTIIAIDfarTML
| . |. ..|. | |. .| |. ..... .| |...|.|||.| |. .. ..|. .. . . |. |||||| |||| .. || .||
gvltvslkkkeefs.dytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvid...aml
IKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE
. .|.. |. . ..|| ..|. |||||.. .|.|
rqakekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 63-306 | 2.7e-51 | 169.0 | In-house | 1-178 (182) | alignment | ||
Range on Protein: 63-306
Range on HMM: 1-178/182.0
NKKKNRFKDILPFEYTRvqlhkiegveGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACrevemakpkCQCYWPqvgesamyg
|..|||..||||....| ..||||||.. |. . ..||.||||..||.||.||.. ..| ...... . .|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
aiqvttdheenvsndfiirqltaecQGEKQVIRQFHYTAWPDHGRPEsATPIIRMIEMFREhrkrHDIPFAIHCSAGCGRTGTIIAIDFARTMlikktip
. ... . |..|. ||||| |. ....||. .| .. | ..|||||.|||||..|... ...
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.......
dKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTNV
.......|...|..|| ||. ..||.|...|. ||.... |..
.gvsleeavklvrsrRpgmvitpnqyfflqlallellllkktrp
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 63-298 | 6.9e-45 | 147.9 | In-house | 56-282 (290) | alignment | ||
Range on Protein: 63-298
Range on HMM: 56-282/290.0
NKKKNRFKDILPFEYTRVQLHkiEGVEGsDYINANYIQGPdgNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQ-VGESAMY
. ||||.||. . ||| |. .| .| ||. |||..| . .| .||.| || |.|||. ... ..| | .| |.||. |.|. || .
efkknrykdvvcndktrvilk..dGydG.dyvhanyvkGl..kamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltf
GAIQVTTDHEENVSNDFIIRQLTAE--CQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHrkrhDIPFAIHCSAGCGRTGTIIAIDFARTMLIKK
|.| |. |.. .. | . |. .| . ... .. .|||. . |. ..|.. . |. | ..||||| |||||..||. . .|..
GeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka....sGpvvvhcsaGiGrtGtfvaievglqilldG
tipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
.||. .|. .|. | . || ||. . ....|
...keldlldlvralrnsrlnsvqvdiqylalveilldl
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 63-296 | 3.7e-35 | 116.0 | In-house | 52-287 (310) | alignment | ||
Range on Protein: 63-296
Range on HMM: 52-287/310.0
NKKKNRFKDILPFEYTRVQLhKIEGVEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYG
. .|||. |.. . .||.| ||. ||| |||.. .| .|||| ||. ||||||. . | ... |. .| .||| ||| .| . ||
ymhknrysdvvcldtsrvkl.kidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetyg
AIQVTTDHEE-------NVSNDFIIRQLTAECQG---EKQVIRQFHYTAWPDHGRPESATPIIRMIEMfreHRKRHDiPFAIHCSAGCGRTGTIIAIDFA
|.|| | |.. |. .. . | .. . .. ||| | |. . . . || | .||||| .|.....|....
cirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrll...aqvrhg.pcvvhcsagkdrlyvvvalklk
RTmliKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIV
| .|.|. .. ...|.| .|. ||... . .
id...kldrglkvdaeevktellksraiciqtelqyliidrvri
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 63-293 | 2.6e-30 | 100.2 | In-house | 50-275 (301) | alignment | ||
Range on Protein: 63-293
Range on HMM: 50-275/301.0
NKKKNRFKDIlPF-EYTRVQLHkIEGVegSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQV-GESAM
.|.|.|.. . | | |.. .| | ||.|. . .||.||||. | .||| |. ....| ..| ...|| . ||. | |. .|.
pkdkhryptv.PckPstavevi.vdGk..rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekld
YGAIQVTTDHEENVSNDFII-RQLTAECQG---EKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKrhdiPFAIHCSAGCGRTGTIIAIDF-ARTM
| .... ..| . |. |. |.| | . . . . |. |.|.| |.| . . ..|. .. .| | .||||| ||. . |. .. || .
igrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksek....PivvhcsaGiGrsvafigteylarev
LIKKTIpdklDVFSIVQQMRKQRPAMVQALDQYVFVYM
. ..|| .. ....|..| || | .. .
eadpti....eltealkhlrehrwngvqtnsqlywmtl
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 63-300 | 4.8e-24 | 79.5 | In-house | 47-280 (303) | alignment | ||
Range on Protein: 63-300
Range on HMM: 47-280/303.0
NKKKNRFKDILPFEYTRVQLHKiegvegSDYINANYIQGpDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYG
| .|||| |.. .....|.| | || |.|.. | . | .| ||.|| |||.|| .. |.. . |. | . .|. . .
nmdknrfvdvicldhskvklsd......ssyihasylel.dsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkfe
--AIQVTTDHEENVSNDFIIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATP-IIRMI-EMFREHRKRHDIPFAI-HCSAGCGRTGTIIAIDFARTMLI
.|.| .. .... . .. |. | . || ||| | ..| ... | .. || | .. .||||.||. .. | |
ersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahlslh
KKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQ
.. ||. ....|. | || | |. .|| . | |
seq..asldlvkclenvrngrlhavqnlsqfsvvytllaehvl
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 63-135 | 1.1e-09 | 32.2 | In-house | 37-114 (347) | alignment | ||
Range on Protein: 63-135
Range on HMM: 37-114/347.0
NKKKNRFKDILPFEYTRVQLHKIEG-----VEGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVI
. .||| || . ||| | . . |||| .|. . . ||| .| |||.|| |||.|. .. |.
slsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvv
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 64-167 | 4.2e-25 | 83.2 | In-house | 48-165 (350) | alignment | ||
Range on Protein: 64-167
Range on HMM: 48-165/350.0
KKKNRFKDILPFEYTRVQLH--------KIEGVEGSDYINANYIQGP------DGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQ
|||.|.|||.| .||.|. | ....|||||||.. . . . |||.|.||| ||.||...| ....... .||. ||.
faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcy
CYWPQVGESAMYGAIQVT
||.. . . . .. .
rYWqegsydditvklask
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 64-300 | 8.2e-24 | 78.8 | In-house | 44-277 (312) | alignment | ||
Range on Protein: 64-300
Range on HMM: 44-277/312.0
KKKNRFKDILPFEYTRVQLHkieGVEgSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGA
| ||. .| .. | | | | || ||... ....|||| |. ||.. .|. | || . || | ..
kdlnrypniqcwdrgrftla...gde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdled
IQVTTDHEEN-----VSNDFIIR---QLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKrhdiPFAIHCSAGCGRTGTIIAIDfarTM
.| |.. . |.| | .. . |.. . .. ...||||| |.| |.. . .| | ||||| |||||.. |. .|
hrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkk....pviahcsagvgrtgtlalie...sm
LIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQ
. | | .| . .||.| |... |||.. ...|..
iaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlefly
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 64-169 | 2.3e-17 | 57.4 | In-house | 49-170 (349) | alignment | ||
Range on Protein: 64-169
Range on HMM: 49-170/349.0
KKKNRFKDILPFEYTRVQLHKI--------------EGVEGSDYINANYIQGPDGNVE--YIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPK
|||.|||||.|..||.|.| .. |||||||.. . .|| ||| | ||| ||.||...| ....|. . | . |
faknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslek
CQCYWPQVGESAMYGAIQVTTD
|. || . | . .| .
cdiywqelsysnitvklqnssl
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 73-206 | 1.3e-09 | 32.4 | In-house | 3-125 (130) | alignment | ||
Range on Protein: 73-206
Range on HMM: 3-125/130.0
LPFEYTRVQlhkiegveGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACrEVEMAkpkcQCYWPQVGESAMYG-AIQVTTDHE
|.||..|.| | .||||... . ||. .| || | |||.|. ...... || . |||. | | ||. .
lefevsrlq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlg.sveee....deywpdsePlewyeediivtltdr
ENvSNDFIIRQL--TAECQGEKQVIRQFHYTAWPDHG
.. .. .| . . .| . |. . || |
de.fknikasnleiesdlneshqaltmfqisnwpsdg
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 74-300 | 1.2e-35 | 118.1 | In-house | 1-172 (178) | alignment | ||
Range on Protein: 74-300
Range on HMM: 1-172/178.0
PFEYTRVQLHKIEGVEGSDYINANYIQGPdgnvEYIAAQGPlphtvNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGEsamygaiqvttdheen
|.. ||| |...||.|.||||||..| . |.....| |...... . | ... . |.|. ..|| |||. .
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
vsndfiirqltaecqgekqviRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMlikktipdKLDVFSIVQQ
|.... .|||| |.. . ...|. .|...... | ..||||| ||.||..|.. ... .|........
.....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl........glsleeaiel
MRKQRPaMVQALDQYVFVYMAIVELVQ
.|..|| .|. .|. ..|. .| .
vrerRp.ivpnpgqlrqLyefelrllk
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 75-305 | 1.5e-21 | 71.8 | In-house | 30-265 (290) | alignment | ||
Range on Protein: 75-305
Range on HMM: 30-265/290.0
FEYTRVQLHKIEGVEGSDYINANYIQGPDGnVEYIAAQGPLPHT-------VNDFWRMIWYHQIEIVIMACREVEMAKP----KCQCYWPQ-VGESAMYG
.| ||| |. .||| ||... |.| .. |. | |. .. ...|| |. ... |.| | | . |. | |. |||. ..
veatrvvLkgygkrfnddyiHAnrvtcpng.lrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfk
AIQVTTdHEENVSNDFIIRQLTAECQGEKQV-IRQFHYTAWPDHGRPESATPIIRMIEMFRehrkRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTi
..| . .|...|.|. . ..|.. . . | . .|. .. .|.. . .. | .|| | | .. ||. . ......
gltvkC.kskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAalaaiilgyQkiaets.
pDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQSLTN
... . ......|||| ... .. || .|| |... | .
.gsvkledvlkalrkqralaitsalelafvdagivllaievldq
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 85-299 | 7.9e-43 | 141.5 | In-house | 6-173 (176) | alignment | ||
Range on Protein: 85-299
Range on HMM: 6-173/176.0
IEGVEGSDYINANYIQGPdgnvEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMygaiqvttdheenvsndfiirqlt
. ...||||||.| |. .|| |||||.|. ||..|.. ..|..|.. . |||... || |||.. . .
lgldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi........................
aecqgekqvirQFHYTAWPDHGRPESaTPIIRMIEMFREHRKRHdIPFAIHCSAGCGRTGTIIAIDfartmLIKKtiPDKLDVFSIVQQMRKQRP-AMVQ
|.... ||||| |.. . .....|. ||..|.. | ..|||||.|||||..|.. |... |.|. .....|.||| .||
...........qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay.....llel..ekglsveealalvreqRplgavq
ALDQYVFVYMAIVELV
.|| |.|... .|
tpeQyrflyefellll
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 89-299 | 3.3e-47 | 156.7 | In-house | 2-225 (272) | alignment | ||
Range on Protein: 89-299
Range on HMM: 2-225/272.0
EGSDYINANYIQGPdgnVE------YIAAQGPLPHTVNDFWRMiWYHQIEIVIMACREVEMAKPKCQCYWP-----------QVGESAMYGAIQVTTDHE
. |.||||... |. .....||||.|..||||. . ..| ... ..|.|... || .||| . .. |||. ||. .|
plsgyiNardvggy...grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllse
EnVSNDFIIRQLTAE---CQGEKQVIRQFHYTAWPDHGRPESAtpIIRMIEMFREhrkrhDIPFAIHCSAGCGRTGTIIAIDFARtmlIKKTIPDKLD--
| . .|.|.| |... || ....|||.||||| |..| .....|.... . |. .|||||..||||..|.. . . .|
e.llldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvalllll...lgvsletivddY
------VFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
.. .|...|.|||..|| .||.|.|.|..||.
lltnlyleeaveelraqrpgavqteeqylflyeallell
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 89-292 | 1.3e-42 | 140.7 | In-house | 3-154 (172) | alignment | ||
Range on Protein: 89-292
Range on HMM: 3-154/172.0
EGSDYINANYIQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREvemakpkcqcywpqvgesamygaiqvttdheenvsndfiirqlTAECQ
||||||||.|. .. ..|| ||||..|..|||||.. ..| ........ . ..
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
GEKQVIRQFHYTAWPDHGRPeSATPIIRMIEMFRE-HRKRHDIPFAIHCSAGCGRTGTIIAIDFARtmlikktipDKLDVFSIVQQMRKQRPAMVQALDQ
.... . |..|. ||||| | .. .....| .| . .. . | ..|||||.|||||..|.. . .|... .|...|..|| .|| .|
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.........lglsleeavalvrekRpgavqnpsq
YVFVY
| |.|
yrfly
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 90-292 | 6.5e-42 | 138.5 | In-house | 1-163 (174) | alignment | ||
Range on Protein: 90-292
Range on HMM: 1-163/174.0
GSDYINANYIQGPDGNVEYIAAQGPLPhtvndFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQvgesamygaiqvttdheenvsndfiirqltaECQG
|||||||... . . ..|| ||||. ||.|.. ..|..|.| ..|.|. . || ||| .
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lred
EKQVIRQFHYTAWPDHGRPESATpIIRMIEMFREHRKR-HDIPFAIHCSAGCGRTGTIIAIDFARTMLIkktiPDKLDVFSIVQQMRKQRPAMVQALDQY
... . |..|. ||||| |.... ...... .|.... .. | ..|||||.|||||..|.. ..|. .. |....|...|.||| ||| .||
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll....eslvdaldlvrelRlqrpgmvqtpsQy
VFVY
|.|
rfly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 90-296 | 1.9e-35 | 117.0 | In-house | 2-150 (151) | alignment | ||
Range on Protein: 90-296
Range on HMM: 2-150/151.0
GSDYINANYIQGPdgnveYIAAQGPLPhtvnDFWRMIWYHQIEIVIMACREVEMAkpKCQCYWPQVGesamygaiqvttdheenvsndfiirqltaecqg
|||||..|. | ... .|||. ||..... ..| ... . |.|.. .| .|.|. |
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
ekQVIRQFHYTAWPDHGRPESATPIIRMIEMFREhrkRHDIPFAIHCSAGCGRTGTIIAIDFARTMlikktipdkLDVFSIVQQMRKQRPAMVQALDQYV
....... |||.| |.| .....|.... . |...|||||.|||||..|.. . ..........|..|| .|| .|..
..ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg.........vsleealeeyrlkrpgvvqpnqqfl
FVYMAIV
|...|.
fqlfall
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 99-292 | 1e-39 | 131.0 | In-house | 2-143 (152) | alignment | ||
Range on Protein: 99-292
Range on HMM: 2-143/152.0
IQGPDGNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWpqvgesamygaiqvttdheenvsndfiirqltaecqgekqvirQFH
|.| . |.||.|||.|.|..|||||.. ..| ...| ....|..|.|| |. |..
idgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qyl
YTAWPDHGRPESATPIIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARtmlikktipDKLDVFSIVQQMRKQRPAMVQALDQYVFVY
.. ||||| |... .. .... ...... . | ..|||||.|||||..|.. . ..... .|...|..|| .|. .|. |.|
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.........lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 104-293 | 4.9e-20 | 66.5 | In-house | 3-198 (199) | alignment | ||
Range on Protein: 104-293
Range on HMM: 3-198/199.0
GNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGE-SAMYGAIQVTTDHEEnVSNDFIIRQLT----AECQGEKQVIRQFH
|. |||.| || .|. |||.|.| ..| . . ||| . .. ||.. ||| . |. | | . . . | ..
gqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktit.tkpdytitaliltnnttappstreishyq
YTAWPDHGRPESATP---IIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFA-RTMLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYM
.|.| .. |. | .. |. . . . .| | .||| | | || ..|.| |. || .|.| . ...|. | .. .|..| |.|
ftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt..svvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 104-293 | 5.3e-20 | 66.4 | In-house | 2-197 (198) | alignment | ||
Range on Protein: 104-293
Range on HMM: 2-197/198.0
GNVEYIAAQGPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGE-SAMYGAIQVTTDHEEnVSNDFIIRQLT----AECQGEKQVIRQFH
|. |||.| || .|. |||.|.| ..| . . ||| . .. ||.. ||| . |. | | . . . | ..
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktit.tkpdytitaliltnnttappstreishyq
YTAWPDHGRPESATP---IIRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFA-RTMLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYM
.|.| .. |. | .. |. . . . .| | .||| | | || ..|.| |. || .|.| . ...|. | .. .|..| |.|
ftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt..svvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 108-197 | 2.4e-10 | 34.4 | In-house | 238-323 (440) | alignment | ||
Range on Protein: 108-197
Range on HMM: 238-323/440.0
YIAAQGPLPHTVNDFWRMIWYHQIEIVIMACReveMAKPKCQCYWPQVGESAMYGAIQVTTDHEENVsNDFIIRQLTAECQGEKQVIRQF
.||.| || || ||||.. ..| .|| . . | ||| | .| . | ||. | .| | . | . ||||
fiatqmpldstvldfwrlvhdyristiimlnq...lndktcsiywpvntrsvtfgpftvghkgsenm.nrvkvrtlelkykeevheirqf
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 110-296 | 1.6e-22 | 74.3 | In-house | 93-285 (302) | alignment | ||
Range on Protein: 110-296
Range on HMM: 93-285/302.0
AAQ--GPLPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWP-QVGESAMYGAIQVTTDHEENVSNDFIIRQ----LTAECQG------EKQVIRQ
. . | |.. .| .| ... ||. | || . || |. .||. .| |.| .. ..| .. | | . |. .
skkpivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdi
FHYTAWPDHGRPESATPIIRMIEmFREHRKRHdipFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDkldVFSIVQQMRKQRPAMVQALDQYVFVYMAIV
....|||||| |. | . . .. | | |. .||||| |||||..|| . . || . | . |||. .|. | || .| ... . .
lafsawpdhGapkeaytaldilk.fcesykkn...vlvhcsaGvGrtGtlvaikyGiqlcskkkvtd...llsivlpvrqcryGavqdeqqliylllcvt
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 115-302 | 9.9e-18 | 59.0 | In-house | 43-230 (263) | alignment | ||
Range on Protein: 115-302
Range on HMM: 43-230/263.0
LPHTVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQ-VGESAMYGAIQVTTDheeNVSNDFIIR--QLTAEC--QGEKQVIRQFHYTAWPDHGRPE
| |.. |...| . | |.| | | .. ||. |.| | .. ..|.| .| .| ... .|. . . . .... |. |... ||
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvctt...kvqsdvllktlellstlgeKkkthtvkhysykgWiekndpe
SATPIIRMIEMFREHRKrhdipFAIHCSAGCGRTGTIIAIDFART-M--LIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQS
| |...... |. .. .|||.| ||. .... | ...| .|| |.....|..|.. .. | | . ....| ..
lareilnilkvarnsks.....lvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnn
|
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subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 118-299 | 2.2e-20 | 67.8 | In-house | 40-221 (255) | alignment | ||
Range on Protein: 118-299
Range on HMM: 40-221/255.0
TVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQ-VGESAMYGAIQVTTDHeenVSNDFIIRQL--TAECQ--GEKQVIRQFHYTAWPDHGRPESAT
||. |...| . | |.| | | .. ||. |.| | .. ..||| . |.| ..| | |.. . . .. ..|. |... || |
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk...ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelar
PIIRMIEMFREHRkrhdiPFAIHCSAGCGRTGTIIAIDFART-M--LIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
| .. . |. . . .|||.| ||. . . .... | ...| .|| |.....|..|.. .. | | . ...||
eilnilkvvrdsk.....svvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 118-298 | 8.3e-16 | 51.5 | In-house | 130-308 (346) | alignment | ||
Range on Protein: 118-298
Range on HMM: 130-308/346.0
TVNDFWRMIWYHQIEIVIMACREVEMAKPKCQCYWPQVGESAMYGAIQVtTDHEENVSNDFIIRQLT--AECQGEkQVIRQ-FHYTAWPDHGRPESATPI
|.||| ||. ||..| . . . . . . | | . . .. .|| | . | . . || | |.. | .| . ||
fvedfwymiyqeqihlvylmvpddklkntttslfndenggyqytgkmfi.nnrradvsgdpkeytievlpegnsd.svicqvhhhapwkhlqqppktlpi
IRMIEMFREHRKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPdklDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
|.|| | .. ... . ||||. ..| .| | | ... |......||| |... || .| ...
ikmihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiep...niceimknikqqrpggvesfaqyasiyaivfdy
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 160-298 | 1.2e-26 | 88.5 | In-house | 12-142 (145) | alignment | ||
Range on Protein: 160-298
Range on HMM: 12-142/145.0
MYGAIQVTTDHEENVSNDF-IIRQLTAECQGEKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHdIPFAIHCSAGCGRTGTIIAIDFARTmlik
.| . .. | |. .... . || |...... . |..|. ||||| |... .....|. .|..|.. | ..|||||.|||||..|.. ..
ylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll....
ktipDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
...........|.||| .|. .|. |.|... ||
....lgvsleealelvrsqrpgavpnpgqlrflyefelel
|
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subfamily_PTEN_pd | Subfamily PTEN | 175-287 | 1e-06 | 23.9 | In-house | 59-168 (184) | alignment | ||
Range on Protein: 175-287
Range on HMM: 59-168/184.0
SNDFIIRQLTAECQGEKQ-VIRQFHYTAWPDHGRPES--ATPIIRMIEMFREHRKRHDIpfAIHCSAGCGRTGTIIAIDFARTMLIKKtIPDKLDVFsiv
.... | |..| . ... . . . . || |. ..|.. ||.. |. |.. . ..|| || ||||..|. . ..|..| . |..|
kdhykiynlrserkydskkfdgrvavypfdDhnppplelleeivediekwleedkknvv..vvHCkaGkGRtGvlivayllkslllek.aeealelf...
QQMRKQRPAMVQALDQ
...| . |. |
aeaRtknkkgvtiPsq
|
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0048179 | (Phosphotyrosine protein) phosphatases II | 176-293 | 6e-24 | 79.8 | In-house | 48-139 (144) | alignment | ||
Range on Protein: 176-293
Range on HMM: 48-139/144.0
NdfiirqltaecqgekqvIRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHdIPFAIHCSAGCGRTGTIIAIDFARtmlikktiPDKLDVFSIVQQMR
. . |.... ||||| |.... .....|...|..... | ..|||||.|||||..|.. . .|.........|
e.................giqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk........klglsleealalvr
KQRPAMVQALDQYVFVYM
..|| .|. .|. |...
srrpgavpnpgqlrfLle
|
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subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 188-298 | 1.6e-18 | 61.6 | In-house | 211-343 (350) | alignment | ||
Range on Protein: 188-298
Range on HMM: 211-343/350.0
QGEKQVIRQFHYTAWPDH---GRPESATPIIR----MIEM--FREHRKR-HDIPFAIHCSAGCGRTGTIIAIDFART-MLIKK---------TIPDKL-D
. |. |... |.| .||| ... .|. ..| . . | .|||||.|||||....|. ..| . . |. |
asdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrD
-VFSIVQQMRKQRPAMVQALDQYVFVYMAIVEL
.. ||...|||| ||| |||..|.| |. .
lisiivnelrkqrismvqnldqfifiYeallfy
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 190-299 | 1.1e-24 | 81.6 | In-house | 87-194 (440) | alignment | ||
Range on Protein: 190-299
Range on HMM: 87-194/440.0
EKQVIRQFHYTAWPDHGRPESATPIIRMIEMFREHR-KRHDIPFAIHCSAGCGRTGTIIAIDfarTMLIKKTIPDKLDVFSIVQQMRKQRPAMVQALDQY
| ....|.|| .|||.| |. | |...||. | . | . |. .|||||.|||| |||.| ..| . |..|.||... ||..|| |||. .||
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavd...silreakrsdqidifsfinsmrnnrpqmvqtpeqy
VFVYMAIVELV
.||. |..| .
afvheavlegl
|
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PTPc_DSPc_SM00012 | 194-296 | 2.2e-33 | 109.9 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 194-296
Range on HMM: 2-104/105.0
IRQFHYTAWPDHGRPESATPIIRMIEMFREHRKRHD--IPFAIHCSAGCGRTGTIIAIDFARTMLIKKTipDKLDVFSIVQQMRKQRPAMVQALDQYVFV
....|||.||||| ||....|..... ...... .. | .|||||.|||||..|.| . .| |.| ...|.| ||...||||| ||| ..||.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket..kevdifqivkelrkqRpgmvqteeqylfl
YMAIV
|.|.
yrall
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 196-287 | 3.7e-08 | 28.7 | In-house | 81-165 (194) | alignment | ||
Range on Protein: 196-287
Range on HMM: 81-165/194.0
QFHYTAWPDHGRPESATPIIRMIEMFREHRKR-HDIPFAIHCSAGCGRTGTIIAIdfartMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQ
... .||.| . | . | ... |. .. . |.|| || |||||..| ||.. .... .. .| || ... |.
eylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa.....YLiyr...lgmsaeeAialfrekRpgaipnqdy
|
|||||||||
PTEN_1 | 196-275 | 2.6e-06 | 22.4 | In-house | 96-171 (196) | alignment | |||
Range on Protein: 196-275
Range on HMM: 96-171/196.0
QFHYTAWPDHGRPESAtPIIRMIEMFREHRKR--HDIPFAIHCSAGCGRTGTIIAidfarTMLIKKTIPDKLDVFSIVQQMR
... ..||| | . ...... | | ... . ..|| || ||.||..| |..| . . ...|...|
eylhfpieDhgapsls.elfdicksfiewllsdpngnvVlVHCkaGlgRsGtvva.....ayLmykgkltadeAlelvrekR
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 197-290 | 7.6e-09 | 30.3 | In-house | 85-167 (182) | alignment | ||
Range on Protein: 197-290
Range on HMM: 85-167/182.0
FHYTAWPDHGRPeSATPIIRMIEMFREHRKRHdiPFAIHCSAGCGRTGTIIAIdfartMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVF
.. .|.|.| . | . |. .. . .. |.|| || |||| .|| .|. . ..|. .. .|..|| .|. .| .
vynfgwkDygva.sleriLdivkvvafalqeg..kvavhChaGlGrtGvliac.....ylvya...krltaekaiklvrskrpksiqtreqvel
|
|||||||||
subfamily_DSP23_pd | Subfamily DSP23 | 199-291 | 8e-07 | 23.8 | In-house | 56-138 (148) | alignment | ||
Range on Protein: 199-291
Range on HMM: 56-138/148.0
YTAWPDHgRPESATPIIRMIEMFREHRKRHDIpFAIHCSAGCGRTGTIIAIdfartMLIKKtipDKLDVFSIVQQMRKQRPAMVQALDQYVFV
.|. | . . ..... | .. . ..|| | |||||..| |.|. || . ..|..|| |....| |
rlriddy.hppaleqvvefvrvveeaeeknea.vsvhcllgrgrtgtmlac.....ylvke...rklaaaeaiaevrrlrpgsvetveqeklv
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 217-299 | 4.4e-15 | 50.3 | In-house | 217-295 (297) | alignment | ||
Range on Protein: 217-299
Range on HMM: 217-295/297.0
MIEMFREHRKRhDIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTIPDkldVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
.| .| . | ... .||||| ||.| .. | ..| || ||| | .|....|.||. .||.|.|. ..| |... .
qleslraempr.nayllvhcsaGvGrsGvvvlsdvilaklrkkripd...vaailsilreqrarlvqtleqfellydavlkkl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 225-297 | 1.4e-13 | 45.2 | In-house | 243-313 (319) | alignment | ||
Range on Protein: 225-297
Range on HMM: 243-313/319.0
RKRHDIPFAIHCSAGCGRTGTIIAIDFARTMLikKTIPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVE
.. . | ..||| | ||||..|| |.| | .. .|. .|...|..| |.. .|| |.| . |
tresqGPlvvhcsdGvGrtGlviasdiairsl..eeskrsvdiPqlvssvrrdrasavltkeqyefiykvlse
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 229-297 | 2.8e-13 | 43.9 | In-house | 265-342 (349) | alignment | ||
Range on Protein: 229-297
Range on HMM: 265-342/349.0
DIPFAIHCSAGCGRTGTIIAIDFARTMLIKKTI-PDKLD--------VFSIVQQMRKQRPAMVQALDQYVFVYMAIVE
.. .||||||||||... .|. .|. . |.. .. || ..|||| .||| | |....| |...
lstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 234-299 | 1.7e-14 | 47.9 | In-house | 3-65 (69) | alignment | ||
Range on Protein: 234-299
Range on HMM: 3-65/69.0
IHCSAGCGRTGTIIAIDFArTMLIKKtiPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
.|||.| |||||.||| || .|.| || ||| || || .|.|.. |.|| .
vhcssgtgrtgtfiaimve.mariks..eklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 234-299 | 3.9e-14 | 46.7 | In-house | 2-64 (69) | alignment | ||
Range on Protein: 234-299
Range on HMM: 2-64/69.0
IHCSAGCGRTGTIIAIDFArTMLIKKtiPDKLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELV
.|||.| ||||| ||| || .|.| || ||| || || ..|.|.. |.|| .
vhcssGtGrtGtfiaimve.mariks..eklvdifnnvqymrkcrpmmvmneneymfihdalveal
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 264-301 | 7.7e-08 | 26.5 | In-house | 363-400 (418) | alignment | ||
Range on Protein: 264-301
Range on HMM: 363-400/418.0
KLDVFSIVQQMRKQRPAMVQALDQYVFVYMAIVELVQQ
...|||| ..|.||| ||| |.||.|.| .|.. . .
dfnlfsivlklreqrpgmvqqleqylfcyktildeiyh
|