Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| fn3 | Fibronectin type III domain | 120-202 | 5.3e-14 | 45.3 | Pfam-A | 2-82 (85) | alignment | ||
Range on Protein: 120-202
Range on HMM: 2-82/85.0
PVDDIIFSSVESVSMTVSWDEVPcnGRNGPITGYYLTYTNITSNT-SYTVNITGGENrMYNLTGLIPYTNYTVSIIPYNYNMTG
.. .. .|.| | |.|.||.. . ..|||||| ..| . ... . ...... .. ..|||| |.|.|.... .| . .|
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngageg
|
|||||||||
| fn3 | Fibronectin type III domain | 228-297 | 9.1e-14 | 44.6 | Pfam-A | 13-84 (85) | alignment | ||
Range on Protein: 228-297
Range on HMM: 13-84/85.0
PTEIIIVWNPPTIPNGIITVYEIRYRESTSTG-PYNITNTTNT-YYSIVGLIPNTSYTIGVRAYTSIGPGEW
.|.. . |.||. ..| || ||..|||..... . ..|.. .| . . || |.|.|.. |.|.. | |..
stsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
|
|||||||||
| DUF4446 | Protein of unknown function (DUF4446) | 502-557 | 4.2e-06 | 15.6 | Pfam-A | 3-57 (152) | alignment | ||
Range on Protein: 502-557
Range on HMM: 3-57/152.0
AILSLLLIVIIIVIIIVVVLISKKKRIKKKYNIAIKDSTDKgTATELGVSSYSTYD
.|. .||.......|...||. | ...||||. .. ...| . || .. .. ..
liiiallvlvvvllillivllvklsklkkkyrklmrgkdgk.sleelleeeleeie
|
|||||||||
| OppC_N | N-terminal TM domain of oligopeptide transport permease C | 502-528 | 7.2e-06 | 11.9 | Pfam-A | 18-42 (56) | alignment | ||
Range on Protein: 502-528
Range on HMM: 18-42/56.0
AILSLLLIVIIIVIIIVVVLISKKkrI
|...| .....|...|.. |.|.
AvvgliillllillaifaPllspy..d
|
|||||||||
| Ig_3 | Immunoglobulin domain | 583-659 | 2.4e-06 | 19.7 | Pfam-A | 2-75 (75) | alignment | ||
Range on Protein: 583-659
Range on HMM: 2-75/75.0
PPVIEEFPNDMTSEEGrqvlFKVKVKVRGNS-KPSFNWYhNGEPVTDDYAHELRGDGSLLLVS-VEKKHKGTYRFVANN
| .. ......||... .. ..|.. .|.. || ...| .. . ... .| | .| | .. |||. ||.|
Pvisvspsptvtsggn....vtLtCsaeggpppptisWy.ietppelqgsegssssestLtissvtsedsGtYtCvasN
|
|||||||||
| I-set | Immunoglobulin I-set domain | 584-672 | 4e-14 | 44.2 | Pfam-A | 1-90 (90) | alignment | ||
Range on Protein: 584-672
Range on HMM: 1-90/90.0
PVIEEFPNDMTSEEGRQVLFKVKvkVRGNSKPSFNWYHNGEPVTDDYAHELRGDG---SLLLVSVEKKHKGTYRFVANNDAGTVSQQVVLTV
|.... ..|.. .|| .| .... |.|. .||..|...|.... . .... .. .| . .||.. .|.|. .|.| ||...... |.|
pkftqklkdvevseGesvelect..veGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
|
|||||||||
| Ig_2 | Immunoglobulin domain | 609-672 | 7.8e-06 | 17.8 | Pfam-A | 23-80 (80) | alignment | ||
Range on Protein: 609-672
Range on HMM: 23-80/80.0
VRGNSKPSFNWYHNGEPVTDDYAHelrgdgsLLLVSVEKKHKGTYRFVANND-AGTVSQQVVLTV
..|| .|.. ||..||... . |.. .|. ...|||. .| |. ...|. | .||
apgnptpkvqwykdgeelsqsqna.......lfipnvsaedsGtYtCrasnsegskqsnsvevtv
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 684-863 | 2.2e-47 | 157.3 | In-house | 15-190 (308) | alignment | ||
Range on Protein: 684-863
Range on HMM: 15-190/308.0
HGDSSSAKIGMIPVDKFGEFVAKghAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrpmsghkDCTNEYINACYIKDY--S
...| ... ..|... ... | |... ... .| | | ... .|.| | || .||. .|. || .|. | | .. |||| |.. |
rdtsilvsslklsvldllkllek..aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.......degsdYInAsyvdgyssk
NQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDS---DTKDYGPFSVTLSDEQVLTDYTVRKMHVKV
.. ..|||||| .||. ||||..|.... .|||.|...| |. || ||||.. ... ||.|.||| .|.|| |||||.....
lprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltn
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 688-870 | 5.3e-47 | 155.3 | In-house | 7-187 (330) | alignment | ||
Range on Protein: 688-870
Range on HMM: 7-187/330.0
SSAKIGMIPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDctNEYINACYIKDYSNQYQYI
.. | .||.|. | . . | |. ||..| | .|. . |. . || ||. ||. || .|. | ...|... .|||| .|. | .. ..|
gnkkyfplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGvee..sdyinasfidGykekdkfi
ATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQR
|.||| ..|. ||||.||. .|| |||.|.. | . ||.||||| . || |.. ||.|| ||||||. |. | . |..
aaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatre
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 691-868 | 2.8e-41 | 137.3 | In-house | 10-179 (297) | alignment | ||
Range on Protein: 691-868
Range on HMM: 10-179/297.0
KIGMIPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESDhtVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHkDCTNEYINACYIKDYSN-QYQYIAT
. .||.. . .. . .|... .....| .| | | ...| | || .||. .|. ||..|. | |. |. | . |||| |.. |. . ..|||
esipiplsvldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyvdgydlltrkfIat
QGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKmKCQQYWPDSDTkDYGPFSVTLSDEQVLTDYTVRKMHVKVleqvT
||| ..|. ||||..|.... .|||.|. .| |. ||.||||.. . ||.|.||| ....| .||||...|. .
qgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn....n
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 693-865 | 5.5e-38 | 125.9 | In-house | 3-173 (325) | alignment | ||
Range on Protein: 693-865
Range on HMM: 3-173/325.0
GMIPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESdHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMsgHKDCTNEYINACYIKDYSNQYQYIATQGP
| | | .. |.| | .|. ..|| ..||.| | .. . .| | || ||| |.| .| .|. | . ..| .|||| |..|. .. ..|.| |
gsiavvnlvehvekkkaqdqdgfahefgllpsddg.iakkvamkpenkaknrfknvvaldksrvvletk..kddpssdyinasylrddkkkdvflaaqaP
VSNTLVDFWRLI--WQersAIIVMITNIIEEGKMKCQQYWPDS--DTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLE
..|. |.|||. |. . .|...|....|| .| .|||. ..| .|.. | | . ..|| |...|| .
ltatindlWrlvldWr...csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvk
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 694-866 | 5.1e-94 | 309.4 | In-house | 1-173 (290) | alignment | ||
Range on Protein: 694-866
Range on HMM: 1-173/290.0
MIPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCTNEYINACYIKDYSNQYQYIATQGPV
.|||||||||||.|||||||||||||.|||||||.||||||||.|||||||||||||||||||||||.|||||||||||||||||.|....|||||||||
lipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpv
SNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQ
||||||||.|||||...||||.|||||||| ||||||||||||.||.||..|..|..|..|. ||..|| ..
sntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknkns
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 694-862 | 8.8e-66 | 216.8 | In-house | 1-164 (287) | alignment | ||
Range on Protein: 694-862
Range on HMM: 1-164/287.0
MIPVDKFGEFVAKGHAKGNEGFRNQFGMLDS-GESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmsghkDCTNEYINACYIKDYSNQYQYIATQGP
.|||.|||||||||||||||||.||| .|.. ..... ||......|| .||...|.|.|..|. |. .. ..||||..|. |......|....|
lipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykekkafiiaesP
VSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVK
..||...||.||.... .|||... |. . .| ||||.... .|.....| .|.| ..|..||..||
mfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevk
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 694-864 | 3.1e-50 | 166.6 | In-house | 4-172 (288) | alignment | ||
Range on Protein: 694-864
Range on HMM: 4-172/288.0
MIPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGhkDCTNEYINACYIKDYSNQYQYIATQGPV
|.|... ..| | .|.|. |....| .| | |.|....| | |. ||. .|. ||..|. |....| . .. |||| ||. | .. ..||||||
eisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgPl
SNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVL
.||. ||||..|.... .|||.|...| |. || ||||..... ||...||| .|.|| |||||...|. |
pntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnl
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 694-865 | 5.5e-48 | 158.5 | In-house | 6-176 (293) | alignment | ||
Range on Protein: 694-865
Range on HMM: 6-176/293.0
MIPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKdcTNEYINACYIKDYSNQYQYIATQGPV
| ..|| |.|.| .|. . .| ... .| . ..|..|.. .. |. ||. ||. || .|. | ...... ...|||| ||..|. . ..||||||.
piklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdes..gsDYinanyipgynsprefiatqGPl
SNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDS-DTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLE
.|. ||||..|...| ||||.|...|.||.||..|||. .. || .||| |..|.|...|..... .
petvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekek
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 694-866 | 1.2e-43 | 144.4 | In-house | 3-173 (307) | alignment | ||
Range on Protein: 694-866
Range on HMM: 3-173/307.0
MIPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCtnEYINACYIKDYSNQYQYIATQGPV
|..|. | . . . . ..|. . . .| . |.|.. .|. |.| ||. .|. .|..|. |... |..| .|||| .|| | .. ..|| |.||
aiaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkeds..dYinasfikgykekkkfiaaqdPv
SNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQ
.|. ||||.|.. . .|||..|. | . ||..|||. |.. || |.| .|. .||. |...| ..
eatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkke
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 694-864 | 1.3e-41 | 138.8 | In-house | 8-188 (307) | alignment | ||
Range on Protein: 694-864
Range on HMM: 8-188/307.0
MIPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGES--DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHkDCTNEYINACYI--------KDYSNQ
.|.. |. .|.. ......|.. .| .| | . .. ...| | || .||. .|. ||..|. | ...|. . .. |||| |. . | ..
fidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlk
YQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSD-TKDYGPFSVTLSDEQVLTDYTVRKMHVKVL
..|||||| ..|. ||||..|.... .|||.|. .| |. || |||||.. .. ||.| ||| .|..| .||||...|. |
rkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdl
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 695-866 | 5.8e-57 | 188.6 | In-house | 5-173 (564) | alignment | ||
Range on Protein: 695-866
Range on HMM: 5-173/564.0
IPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGeSDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCtnEYINACYIKDYSNQYQYIATQGPVS
|||... |.||| .|... | ... ...| . .|... | || ||.|||| || .|. |... |.... .|||| .|. | .. .|||||||..
ipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegs..DYINAsfidgyrkrkayIAtqgPla
NTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQ
.|. ||||..|...|..|||.|.. |.|| ||..|||...|. || . |||..|. |.||..|.. .| ..
etiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkks
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 695-866 | 5.2e-51 | 168.5 | In-house | 1-175 (563) | alignment | ||
Range on Protein: 695-866
Range on HMM: 1-175/563.0
IPVDKFGEFVAKGHAKGNEGFRNQFGMLDS--GESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCTnEYINACYIKDYSNQYQYIATQGP
.||..| . ||. ||.|. || ..| | | ..| ... |.|| || ||| || |..|.|..|.|. .|||| ||. | . ..||||||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyidGyqkskafiatqgp
VSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVL--EQ
. .|. ||||.||....||||||||. |.|. ||..||| ....|| ..||| .|.||. ||||.. .| | ..
lkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkk
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 695-869 | 6.5e-50 | 165.0 | In-house | 2-174 (318) | alignment | ||
Range on Protein: 695-869
Range on HMM: 2-174/318.0
IPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKdcTNEYINACYIKDYSNQYQYIATQGPVS
|.|... . |.. ...|. . ... .|. |. | . |.| || ||.|||. ||. |. |....|.. . .|||| || | .. .|||.|.|..
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegee..gsDyinanyidGyrrkkayiaaqaPlp
NTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQ
.|. ||||..|. ||.|||.|.. |.||.|...|||..... || |.|..| |.||..|...|. |. .
etieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeees
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 695-863 | 5.6e-47 | 155.3 | In-house | 4-170 (305) | alignment | ||
Range on Protein: 695-863
Range on HMM: 4-170/305.0
IPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGesDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKdcTNEYINACYIKDYSNQYQYIATQGPVS
| .|.. ... . ... ..|. .|. .| . .... || . || ||...|...||.|| |.. . .. ..||||.|.. |... .||..|||.
ialddlaayikearvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdgykrkkkyivaqgPlk
NTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTK--DYGPFSVTLSDEQVLTDYTVRKMHVKV
||..||||||..|. |||.|...|.|| ||.||||.| |. ..|.|||.|..|. .||. ||... .
ntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisi
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 695-864 | 6e-45 | 148.7 | In-house | 5-171 (319) | alignment | ||
Range on Protein: 695-864
Range on HMM: 5-171/319.0
IPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESDhTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCtnEYINACYIKDYSNQYQYIATQGPVS
|.|... | . . ...|. .....| .|. ...| |.. .. || ||. ||. || |..| .. | .. .|||| .| | .. ..||||.|..
ievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegs..dyinasfidgyqerekfiatqaPle
NTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVL
||. ||||..|.|.| |.||.|.. |..|.|...|||. . ..|| . ||| .|. | || .||.... .
ntiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkk
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 695-863 | 1.1e-41 | 138.6 | In-house | 2-166 (278) | alignment | ||
Range on Protein: 695-863
Range on HMM: 2-166/278.0
IPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGESdHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDctNEYINACYIKDYSNQYQYIATQGPVS
|.| .. ..... ..... .....| |.| | ...| | || .||. .|. || .|. | ...|. | . |||| |.. |. . ..|||||| .
isvkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdld..sdYinAsyvdgynvprkfiatqgPlp
NTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPdSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKV
.|. ||||..|.... .|||.|. | |. ||.|||| .... ||.|.||| .|..| |||||...|.
etvedFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtn
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 695-867 | 4.3e-40 | 132.6 | In-house | 6-174 (315) | alignment | ||
Range on Protein: 695-867
Range on HMM: 6-174/315.0
IPVDKFGEFVAKGHAKGNEGFRNQFGMLDSGEsDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrPMSgHKDCTNEYINACYIKDYSNQYQYIATQGPVS
||.|.. .||. .| ..||.... . |. | . | || ||. ||. || |. | |. .| .|.|| .|. |. . .|||.|||
ipldqlityvaqkkastkngfkqdyesipggq.lhpldvakkienkqknryiniiaydksrvql.pll.endphsdyvnanfidGynkkrryiaaqgpnv
NTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSdTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQV
... |||||...| . |||.||..|. | |...|||| ||...||. .|.| |.|||| . | . ...
asvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtlsvvfgdni
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 695-862 | 7.4e-35 | 115.3 | In-house | 3-167 (315) | alignment | ||
Range on Protein: 695-862
Range on HMM: 3-167/315.0
IPVDKFGEFVAKGHAkgNEGFRNQFGMLDSGESdHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSghKDCTNEYINACYIKDYSNQYQYIATQGPVS
||| .| || | . | ..| | . . .|. .. | ||. ||. .| .|. | . .. ..|||| ||| . .. |||.|||
ipvaqfpafvnknrh..talfseefhdlpdPdi.yrqrvaretinfkknryknilPldsarvklevid..dsPdsdyinasyiksvdddkayiasqgPlk
NTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPD--SDTKDYGPFSVTLSDEQVLTDYTVRKMHVK
.. ||||...||. . |||.|. |. |.||.||||| .|. ..| ..|.| . . || ..||. ..
asvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtr
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 695-861 | 1.1e-29 | 98.5 | In-house | 10-168 (297) | alignment | ||
Range on Protein: 695-861
Range on HMM: 10-168/297.0
IPVDKFGEFVAKGHAkgNEGFRNQFGMLdsGES-DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSghKDCTNEYINACYIKdySNQYQYIATQGPV
||. .| .| |.. . |...| | |. .. || | .|..||. || .|..|. . .| .|.|| ..| .|....|.|| |
iplsdfatlvqknrh..tdvfseeflcl..peaniqpqtvaekkvnfeksRYkniLPydssRvkLaivn..ddpdsDyvnasfvk..gnkhrlittqmPm
SNTLVDFWRLIWQERSAIIVMITNIIEEGKmKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHV
.|. |||.....|. ..|||... |. | ||..||.|. .. .| ||.|. . . . |...|
katvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelev
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 695-836 | 2e-23 | 77.5 | In-house | 4-148 (392) | alignment | ||
Range on Protein: 695-836
Range on HMM: 4-148/392.0
IPVDKFGEFVAKGHAkgNEGFRNQFGMLDSGESdHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDctNEYINACYIKDYSNQYQYIATQGPVS
||| .| || | . . | ..| | . . . ||. .. |. ||. ||. || .|. | . | ..|.|| ||. . |. |||.||| .
ipvaqfpafveknrh..salffeefhdlpgpdi.ypqtvaqkeinlkknryknilpydsarvkleviddipd..sdylnasyipsfdnekayiasqgpna
NTLVDFWRLIWQERSAIIVMITNIIEEGK----MKCQQY----WPDSDTK
.| ||||...||. . |.|.|.. | | . |. |||.|
aslddfwrmvfqenvttiamvtklkegdkgddartvaqfhftewPdkdvp
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 695-791 | 9e-11 | 35.8 | In-house | 5-95 (95) | alignment | ||
Range on Protein: 695-791
Range on HMM: 5-95/95.0
IPVDKFGEFVAKGHAKGNEGFRNQFGMLDSgESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrpmSGHKDctNEYINACYIKDYSNQYQYIATQG
| | | | . |.. .. | |.| . | . ||| . .| ||| ||. || |..| . ..| .|||||.. |. . |||.||
ihvsvfhshvlemhsnsdqefdnefksism.tsgapytvgsseanipknrflnifpydatrvvl...ttkrd..sdyinacfvdgyarkncyiaaqg
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 698-862 | 1.6e-26 | 87.7 | In-house | 5-164 (439) | alignment | ||
Range on Protein: 698-862
Range on HMM: 5-164/439.0
DKFGEFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPS--NKLLNRFANIVVYDDNRITLRPMSGHKDctNEYINACYIKDYSNQYQYIATQGPVSN
|.| | | | . . .| |.. | ...| . |... |. .. ||. ... .| |.||. . | |||| ||| | .. ||||||| .
defqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvph..shyinanyikGyyddklyiatqgpkke
TLVDFWRLIWQERSAIIVMITNIIEEGKmkcqqYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVK
| |||||....... |||.||..| | ||| .. || .| . | .|..| ..|
ttddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvf
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 698-778 | 6.4e-07 | 23.0 | In-house | 9-84 (440) | alignment | ||
Range on Protein: 698-778
Range on HMM: 9-84/440.0
DKFGEFVAKghAKGNEGFRNQFGMLDSGESDHTVTVGLtPSNKLLNRFANIVVYDDNRITLRPMSGHKDctNEYINACYIK
| ..| . . | ... .| || |. . .| |.||. ||. ||..|| .|. | . | | ..|||| ||.
adfadyvqn..nrrsrafedewsllpsglsqpsdiasl.pnnkvknryrnilaydhsrvmleevkgvpd..sdyinasyin
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 699-863 | 7e-45 | 149.1 | In-house | 4-165 (317) | alignment | ||
Range on Protein: 699-863
Range on HMM: 4-165/317.0
KFGEFVAKGHAKGNEGFRNQFGMLDSGESDhTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDctNEYINACYIKDYSNQYQYIATQGPVSNTLV
.. ... . ..... .....| .|.| | | .|.. | || .||. .|. ||..|. | |..|. | . |||| |.. .. . ..|||||| .||.
dlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdld..sdYInAsyvdgpnlkrkfIatqgPlpntve
DFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKV
||||..|.... .|||.|. | |. ||.||||. .|. ||.|.||| .|..| ..|.|...|.
dFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtleved
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 700-867 | 4.4e-44 | 145.9 | In-house | 14-182 (298) | alignment | ||
Range on Protein: 700-867
Range on HMM: 14-182/298.0
FGEFVAKGHAKGNEGFRNQFGMLDSGES---DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCtnEYINACYIKDYSNQYQYIATQGPVSNT
. ...|. ..|. |. ..| |.|..| ... .|. .|.|| ||.|.|. .| |. |. ... ... .|||| ... |... .||||.|. .|
lqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadees..dYiNAsflhaykgrnafiatqaPltet
LVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQV
..||||....| .. |||.||. | .|.|...||||. .. || ..|.| ... .|..|||..|. ..
vedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkee
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 701-847 | 4e-24 | 79.7 | In-house | 15-158 (310) | alignment | ||
Range on Protein: 701-847
Range on HMM: 15-158/310.0
GEFVAKGHAKGNEGFRNQFGMLDSgESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmsGHKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDF
.|. | ||. .|. ||. . | ..| . ||....|. |. |. |. | ..|| | |.| . .| .|||. |..||
enfiiateklgieglvkqyrklda.kqdssltyeaykkymhknrysdvvcldtsrvklk...idksryedyihanyvktnylrstficsqgplqhtiidf
WRLIWQERSAIIVMITNIIEEGKMKCQQYWPDS-DTKDYGPFSVTLSD
||.|.|||. |... .. |||. || ||| |. || ||
wrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnls
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 702-865 | 1.9e-47 | 156.7 | In-house | 10-170 (288) | alignment | ||
Range on Protein: 702-865
Range on HMM: 10-170/288.0
EFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPmsGHKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFW
. ||| .|....|| ... | . |....||.| . |. ||. ||. || .|. |. ... ...|||| ||... .. .|||||||. .|. |||
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkk..leeeagaDYinasyidgekkkkkyiatqgPladtvndfW
RLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDT-KDYGPFSVTLSDEQVLTDYTVRKMHVKvlE
.|...... |||.|...|.|| ||..||||.|. | || . ||| ... |.|...||. ..
elvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..k
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 702-870 | 1.3e-37 | 124.4 | In-house | 5-173 (297) | alignment | ||
Range on Protein: 702-870
Range on HMM: 5-173/297.0
EFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKdcTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFW
|.|| ..||..| .... . . . |... ...| ||..... ||. |..| ..... . .|||| .. | .. .||||||. .| |||
elvayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdede..asdyinanfvdGykqkkafiatqGplkktvsdfW
RLIWQERSAIIVMITNIIEEGKMKCQQYWP--DSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQR
|..|... .|||.| ..|.|..||.|||| . .....| .||. . .. ||.||....| .. .|
rmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesr
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 702-837 | 6.2e-19 | 62.9 | In-house | 11-140 (305) | alignment | ||
Range on Protein: 702-837
Range on HMM: 11-140/305.0
EFVAKGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHkdctnEYINACYIKDYSNQYQYIATQGPVSNTLVDFW
.|| . || .|.|..| . . . . .. ||. .. |.||. |.. | ||| | |. .| ..| || |. .| |||
kfvkrtlekgpaglraefvamkrfndfekmkafkeaqeagknrykdvgcldnnrvklegpwph.....eyihanyvstptnpkrfictqaplektcadfw
RLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDtKD
. .|.. | |. |..| | ||..|.. | ||
ymclqdkveaifmlcnllekgakkcleyfaskd.kd
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 704-836 | 2.2e-20 | 67.9 | In-house | 7-134 (307) | alignment | ||
Range on Protein: 704-836
Range on HMM: 7-134/307.0
VAKGHAKGNEGFRNQFGMLDSGEsDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmsgHKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRL
| . || . ....| .| . ..||| .| ||. .. . | .|| .. . . .|| | |. . ..|..||| || .|| .
vqrtldkgvqalvdefrvlakkt.pegvtveafsantdknryqdvkcqdkgrivvk....fdglasdyihanylgiaikpkkficaqgplentqysfwam
IWQERSAIIVMITNIIEEGKMKCQQYWPDSDTK
. ||. ..|. ..|| .|.||.|||| . .
aiqekvesvimlckvielakikceqywpleegq
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 706-866 | 1.4e-42 | 140.7 | In-house | 19-181 (306) | alignment | ||
Range on Protein: 706-866
Range on HMM: 19-181/306.0
KGHAKGNEGFRNQFGMLDSGESDHTV--TVGLTPSNKLLNRFANIVVYDDNRITLRpmsGHKDCTNEYINACYIKD--YSNQYQYIATQGPVSNTLVDFW
... ....|| ..| |. |. ... . | |.|| ||. ||. .|..|..|. .. ..|||| |||. ... .|||||| ...|. |||
eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFW
RLIWQERSAIIVMITNIIEEGKMKCQQYWPDSD-TKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQ
|..||| | .|||.|. .| || || .||||. ...|| ||| .|. |.||..|...|. ..
rmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkk
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 706-861 | 6.9e-24 | 79.3 | In-house | 14-164 (418) | alignment | ||
Range on Protein: 706-861
Range on HMM: 14-164/418.0
KGHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGhKDcTNEYINACYIkDYSNQYQYIATQGPVSNTLVDFWRLIW
| | | ...| .|. . | | ||..||. . |. |. . |. ..|||| || | . |.|.||||. ||. ||||..|
knhikcihkikeefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqd.ke.gsdyinanyi.dgaypkqfictqgplpntiadfwrmvw
QERSAIIVMITNIIEEGKMKCQQYWPDSDTKDygPFSVTLSDEQVLTDYTVRKMHV
..| ||||.. |. ..||..|||. . ||. ..|. |.| . |
enrcriivmlsresencrikcdrywpeqigge..qfsiygngnevfgtysvelvev
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 707-863 | 5.3e-41 | 135.6 | In-house | 9-164 (281) | alignment | ||
Range on Protein: 707-863
Range on HMM: 9-164/281.0
GHAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSghKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQ
... |.|| ... | . . |.| | .. |.| ||. ||| || |... | . .. ...|||| ... |... .|||||||| ..||.||...|.
lsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpne..enkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvwe
ERSAIIVMITNIIEEGKMKCQQYWPDSD-TKDYGPFSVTLSDEQVLTDYTVRKMHVKV
.. .|||.|. ||.||.|| .|||| . . || . |. |. . | ||....
qkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkler
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 708-864 | 1e-43 | 145.2 | In-house | 8-162 (297) | alignment | ||
Range on Protein: 708-864
Range on HMM: 8-162/297.0
HAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrpmsghKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQE
..... ... .| |.. . . .|.| | |. .||. .|. ||..|. | .| . ||||.|.. |. ....|||||| .||. ||||..|..
kllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweq
RSAIIVMITNIIEEGKMKCQQYWPDS--DTKDYGPFSVTLSDEQV--LTDYTVRKMHVKVL
.. .|||.|. .| |. ||.||||. ... ||.|.||| ...| |.|||.|...|. .
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdt
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 708-864 | 1.2e-43 | 144.9 | In-house | 7-160 (273) | alignment | ||
Range on Protein: 708-864
Range on HMM: 7-160/273.0
HAKGNEGFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLrpmsghKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQE
...|. ... .| .| | ..| .|.| | || .||. .|. ||..|. | .| .. |||| |.. | . ..|||||| .||. ||||..|..
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweq
RSAIIVMITNIIEEGKMKCQQYWPDSD---TKDYGPFSVTLSDEQVLTDYTVRKMHVKVL
.. .|||.|...| |. || ||||.. .. ||.|.||| .|.. |||||.. .. |
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnl
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 710-882 | 2.7e-49 | 162.5 | In-house | 12-185 (301) | alignment | ||
Range on Protein: 710-882
Range on HMM: 12-185/301.0
KGNEGFRNQFGMLDSGEsDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERS
| ...| .|. |..|| |.. ||||. .|| |||| ||.|||||||.|.|.. . |..||||| ||..||.. ..||.|||. .||||||||||||.
khsnkfeeqykelkege.dksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekp
AIIVMITNIIEEGKMKCQQYWPDSD--TKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQRPDEVTHNIASQN
. |||.|| |. | ||.||||.|. ....|||.|||..|||. |...|.. ||. . . | . .. |..
vsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 710-862 | 4.2e-39 | 129.1 | In-house | 6-153 (283) | alignment | ||
Range on Protein: 710-862
Range on HMM: 6-153/283.0
KGNEGFRNQFGMLDSGESDHTVTVglTPSNKLLNRFANIVVYDDNRITLRPMSGhkdctnEYINACYIK---DYSNQYQYIATQGPVSNTLVDFWRLIWQ
..|. ||... | . | .... . || ||. .||..| .|. |.. | .||||..| .| .. .||..|.|. .| ||||.....
nnnklfrevlkrlsvpdldadias..adenkrknrnqeivpadqwrvelksesr......dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfd
ERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVK
|. . |||.|.. |. ..|| |||| ..|||.| ||| .| ...... ..
ekitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllr
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 710-869 | 7e-34 | 112.0 | In-house | 12-170 (288) | alignment | ||
Range on Protein: 710-869
Range on HMM: 12-170/288.0
KGNEGFRNQFGMLDSGESDHTV--TVGLTPSNKLLNRFANIVVYDDNRITLRpmsghkDCTNEYINACYIKDYSNQ-YQYIATQGPVSNTLVDFWRLIWQ
.|. .. ..| |.. . .. .. . . ||. .|. || ||..|| . ...||||...|| | . ..||||.| .|| |||.....
dgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr......gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvye
ERSAIIVMITNIIEEGKMKCQQYWPDS--DTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQ
..| .|||... | || |...||| . .|. .|..||||.... . . |......|.. .
qkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadav
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 714-869 | 5.6e-38 | 125.5 | In-house | 23-170 (314) | alignment | ||
Range on Protein: 714-869
Range on HMM: 23-170/314.0
GFRNQFGMLDSGesdhtVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGhkDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIV
||.... | | . |. ||. .|. || |..| .. | | ..|||| .| | . ..|.||||. .|. |||||...|..| ||
gfkeeyeslfeg.....wdaakkdenreknrsgdilaydrsrvflitidg..dpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasiv
MITNIIEEGKMKCQQYWPDSDTKdYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQ
|.|...|.|..|| .|||. .. ||.. |.| . ..|... || . |. |.. .
mltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqe
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 714-849 | 9.9e-22 | 71.9 | In-house | 12-148 (281) | alignment | ||
Range on Protein: 714-849
Range on HMM: 12-148/281.0
GFRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCTnEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIV
|...| | .|| | |. ||..|| . | |. |. |. | .|| | ||. . || |||| .| ||||.|||| .. ||
dfkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknst.dyihanyirspflkrgyiltqgpkketradfwrmiwqenttaiv
MITNIIEEGKMKCQQYWPDSD--TKDYGPFSVTLSDEQ
|. ...| . || .|.| .. .||. |
mlcqfletnrekcaeyfprnahcclqfdklsvsyedst
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 715-865 | 3.1e-43 | 143.6 | In-house | 2-159 (284) | alignment | ||
Range on Protein: 715-865
Range on HMM: 2-159/284.0
FRNQFGMLDSGESDH--TVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHkDCTNEYINACYIKDY-----SNQYQYIATQGPVSNTLVDFWRLIWQE
.. .| .| | .. ...|.| | |. .||. .|..||..|. |....|. . ...|||| |.. | .. ..||||||..||. ||||..|..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgd.ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
RSAIIVMITNIIEEGKMKCQQYWPDSD-TKDYGPFSVTLSDEQVLTDYTVRKMHVKVLE
.. .|||.|...| |. || ||||... .. ||.|.||| .|.| |||||.. .. |.
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlg
|
|||||||||
| DSPc_SM00195 | 715-874 | 3e-41 | 136.9 | In-house | 2-160 (263) | alignment | |||
Range on Protein: 715-874
Range on HMM: 2-160/263.0
FRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHkdCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVM
....| |.. .|....| . ..|| ||. ||..||..|. | . .. ...|||| ||| .... .||||||| ..|. ||||..|.|.. ||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
ITNIIEEGKMKCQQYWPDS--DTKDYGPFSVTLSDEQVLT-DYTVRKMHVKVLEQvtQRPDEV
.|. |.|| ||..|||.. .....| .||.| ... ....|..... .. . . .|
lteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk..eetrkv
|
|||||||||
| PTPc_SM00194 | 715-874 | 3e-41 | 136.9 | In-house | 2-160 (263) | alignment | |||
Range on Protein: 715-874
Range on HMM: 2-160/263.0
FRNQFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHkdCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVM
....| |.. .|....| . ..|| ||. ||..||..|. | . .. ...|||| ||| .... .||||||| ..|. ||||..|.|.. ||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
ITNIIEEGKMKCQQYWPDS--DTKDYGPFSVTLSDEQVLT-DYTVRKMHVKVLEQvtQRPDEV
.|. |.|| ||..|||.. .....| .||.| ... ....|..... .. . . .|
lteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk..eetrkv
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 718-870 | 3.7e-35 | 116.2 | In-house | 20-171 (280) | alignment | ||
Range on Protein: 718-870
Range on HMM: 20-171/280.0
QFGMLDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmsghkDCTNEYINACYIKDYSNQ----YQYIATQGPVSNTLVDFWRLIWQERSAIIV
|| .| . . .... | | ||. .|. ||. |..|. . ...|||| |.. .. .|||||||...| |||...|...| .||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklk......esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssliv
MITNIIEEGKMKCQQYWPDS-DTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQR
|.|...|.|..|| ||||.. |. .|| |||... |. . | .|.. .| |. .|
mlttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeer
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 722-864 | 5.8e-39 | 129.5 | In-house | 16-144 (278) | alignment | ||
Range on Protein: 722-864
Range on HMM: 16-144/278.0
LDSGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITlrpmsghkdctnEYINACYIKDYsnQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEE
| . . ..|..| ..|. .||. .|. || .|. .|||| ||. | . ..|||||| .|. ||||..|.... .|||.|. .|
llllgipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvel
GKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVL
|. || ||||..... ||.|.||| .|.|| |||.|...| |
grekcaqywpeggsltygdftvtllseevlddytlrtllvtnl
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 724-876 | 9.5e-29 | 95.0 | In-house | 17-166 (290) | alignment | ||
Range on Protein: 724-876
Range on HMM: 17-166/290.0
SGESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmsghkDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGK
||..... .|.|. |||. .. || ||.|. . |.|||| .. . .|| ||||..|| ||...|...| .||. ...|...
keasdfptreaklpenrnlnryrdvspydhsrikle......radndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeq
MKCQQYWPDSDT-----KDYGPFSVTLSDEQVLTDYTVRKMHVKVLeqVTQRPDEVTH
.||.|||| . . ..|.| |.. ||||..... | ||. |..|
ikcaqywPqgeeekellledtklkvkliseerksyytvrllelenl..ktqetreilh
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 724-887 | 1.1e-23 | 78.5 | In-house | 34-195 (350) | alignment | ||
Range on Protein: 724-887
Range on HMM: 34-195/350.0
SGESDHTVTVGLTPSNKllNRFANIVVYDDNRITLR----P--MSGHKDCTNEYINACYIKDY------SNQYQYIATQGPVSNTLVDFWRLIWQERSAI
| | .. |. | ||. ||. |. .|. |. . | ||.|||| |.| ...|||||.|. .|. ||...| . .
spsnDvilseGvelfak..nrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkv
IVMITNIIEEGKMKCQQYWPDSDTKDygpFSVTLsdeqvltdyTVRKMHVKVLEQVTQRPDEVTHNIASQNNDRNR
|...|. .| . ||..||.. . .| . | | . .. . ....... .| .. . .|. .
ilsltsdvelnlekcyrYWqegsydd...itvkl.........askwenimgindsslysadvkkeasdndnisdd
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 724-845 | 1.2e-12 | 41.9 | In-house | 35-165 (349) | alignment | ||
Range on Protein: 724-845
Range on HMM: 35-165/349.0
SGESDHTVTVGLTPSNKllNRFANIVVYDDNRITLR----PMSGHKD-------C-TNEYINACYIK--DYSNQYQYIATQGPVSNTLVDFWRLIWQERS
| | .. |. | ||. .|. |. |. |. . . | . ..|||| |.| .| . .||||| |. |. ||...| ..
seiddvilseGvelfak..nrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngv
AIIVMITNIIEEGKMKCQQYWPDSdtkDYGPFSVTL
... ... |.. ||..|| . .| . | |
klvlsLnddkelslekcdiywqel...sysnitvkl
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 725-861 | 2.1e-30 | 100.3 | In-house | 29-165 (515) | alignment | ||
Range on Protein: 725-861
Range on HMM: 29-165/515.0
GESDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSghKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKM
| . || | ||. ||. || .|. | . . ..|.|| ||. . |. |||.||| .. |||||..||. . |.|.|. |. |.
gpniypqtvaqeeinfkknryknilPydsvrvklevin..dnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdki
KCQQYWPD--SDTKDYGPFSVTLSDEQVLTDYTVRKMHV
|| .|||| .|. .| ..| | . |. . ||..|
kcgkyWPdkpgdsvkfGsikvelvsleactggikrkltv
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 726-869 | 7.8e-30 | 98.6 | In-house | 42-186 (297) | alignment | ||
Range on Protein: 726-869
Range on HMM: 42-186/297.0
ESD-HTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKdcTNEYINACYIKDYS-NQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGK
|.. .| .|. .. | || .... ||..|..|. . .. ...|||| | | . |||||||...|. |||...|.. ...||..|.. |||
eaepstkevakaeknvkknrskavlpydhsrvklkeeasae..ksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegv
MKCQQYWPDSDTKDYGPFSVTLSDEQVLT-DYTVRKMHVKVLEQVTQ
.|..|||| .. |. . | | | . . || || ...| |..
kqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtset
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 727-870 | 2.8e-31 | 103.6 | In-house | 37-183 (300) | alignment | ||
Range on Protein: 727-870
Range on HMM: 37-183/300.0
SDHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMsghKDCTNEYINACYIKDY--SNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKM
| ..... | |. ||| ... |.|||. | | |. ...|||| || .....||..|||. .|. |||...|.. ..|||.|...|.||
edallstaklpenaeknrfkdvlPyednrvelspt...kenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgke
KCQQYWPDS----DTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQR
|. .|.|.. .| ..| | || . . .. .....| | .|
ksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeer
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 727-842 | 7.5e-16 | 54.2 | In-house | 34-168 (314) | alignment | ||
Range on Protein: 727-842
Range on HMM: 34-168/314.0
SDHTVTVGLTPSNKLLNRFANIVVYDdNRITLrPMSGHKDCTneYINACYIKDYsnqYQYIATQGPVSNTLVDF----------WRLI--WQERSAIIVM
...|..|. . |. ||. .|. .| || | | ..... |||| |.. . ..|||||| ..|.||| ||.. .. .. .|||
peltilvadlflnrdknryldilpad.nrvil.pglpvsgsd..yinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivm
---------------------ITNIIEEGkmkcqQYWPDSDTKDYGpfS
.... . | ... .| ... .
srdevladelsrLdaAlgKtpllildgng.....neptaadlellk..e
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 728-866 | 5.9e-30 | 99.5 | In-house | 26-162 (273) | alignment | ||
Range on Protein: 728-866
Range on HMM: 26-162/273.0
DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGhkdctneYINACYIKDY--SNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMK
|..|| . .|| ||. |.. ||. |..| .| |||| .|| ..|.|||.|||. .| |||...|. .. .|.|.|. |.||.|
ldtcevgkkkenkdknryrnvlPydetrvklgdegg.......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvk
CQQYWPDSDTKD---YGPFSVTLSDEQVLTDYTVRKMHVKVLEQ
|..|||.| | .. . |.| . | | ...||...|| .|
chrywPesknkklkvsnrlevellkvqkldgfvvralavkdses
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 728-836 | 7.6e-16 | 52.6 | In-house | 29-133 (307) | alignment | ||
Range on Protein: 728-836
Range on HMM: 29-133/307.0
DHTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHkdCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEgkMKCQ
. ..| .. |. | . | |..|. | ....| | ..| ..| .| |. || ||||...||. |||.| | .|.
eislttaasdnnlekarskrvhckdssrvklelrrGq..ylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erce
QYWPDSDTK
||| ....
yywpkaesd
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 729-863 | 1.2e-37 | 124.4 | In-house | 30-165 (290) | alignment | ||
Range on Protein: 729-863
Range on HMM: 30-165/290.0
HTVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKdcTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQ
.. ..| ...|. ||. .|. || .|..|. ..... ..|||| .|| ... .|||.|||...|| ||||.||. . |.||. ...| ||.||..
ysteagekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCer
YWPDSDTK--DYGPFSVTLSDEQVLT-DYTVRKMHVKV
|||.. . .|.|.|||..|. .. |...| ..|..
YWpeegeeelefgefevtleeekavdddflirtLkvea
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 729-863 | 3.9e-19 | 63.7 | In-house | 23-150 (267) | alignment | ||
Range on Protein: 729-863
Range on HMM: 23-150/267.0
HTVTVGLTPSNKLLNRFANIVVYDDNRITLRpmsghkDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEgkmKCQQ
|.. .. |. ||. . . |||.|. || . ..||||| |.. | . ..|.||.|..|| ||. .| ... ..||..|.. .. . ..
stisqsiaeknqernrlddnlpyddtrvilr......tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftd...nirl
YWPDS--DTKDYGPFSVTLSDEQVLTDYTVRKMHVKV
.|| ..| | ..| | |. || . . .|.
fwPPkmgqakkyqdltvehslekeendyqiitlelkf
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 730-864 | 5.7e-36 | 119.8 | In-house | 2-134 (249) | alignment | ||
Range on Protein: 730-864
Range on HMM: 2-134/249.0
TVTVGLTPSNKLLNRFANIVVYDDNRITLRPMSGhkDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQY
...|.| | || .||. .|. || .|. | ...| . |||| ||. | . ..|||||| ..|. ||||..|.... .|||.|. | |. ||.||
eysvallpenkdknrypdilpydhsrvklsilpg..lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqy
WPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVL
||..... || |.||| ...|. |||||..... |
wplggsleygdftvtllsvevkddytvrtleltnl
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 732-862 | 1.4e-32 | 108.3 | In-house | 54-176 (319) | alignment | ||
Range on Protein: 732-862
Range on HMM: 54-176/319.0
TVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKdcTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITniieegKMKCQQYWP
| . || ||. ||. .| |.. |... | .|||| ... | .. .|||.||| ||| ||||.||. ... ||..| | || ||||
tfanldqnkdknriinilafdknvvklerliGee..fsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywp
DSDTKDYGPFSVTLSDEQVLTDYTVRKMHVK
. .. | | .. . .|.||....
lkivikeerfkvkvdsveetaeyvvrdiels
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 732-862 | 2e-32 | 107.8 | In-house | 18-140 (284) | alignment | ||
Range on Protein: 732-862
Range on HMM: 18-140/284.0
TVGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKdcTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITniieegKMKCQQYWP
| . || ||. .|. .| |.. |... | .|||| .|. | .. .||||||| ||| ||||.||. ... ||..| | || ||||
tfanldqnkdknrighilafdknvvklerliGee..fsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywp
DSDTKDYGPFSVTLSDEQVLTDYTVRKMHVK
. .. | | .. . .|.||....
lkivikeerfkvkvdsveeseeyvvrdiels
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 732-865 | 2e-32 | 108.1 | In-house | 3-127 (243) | alignment | ||
Range on Protein: 732-865
Range on HMM: 3-127/243.0
TVGLTPSNKLLNRFANIVVYDDNRITLrpmsghKDctNEYINACYIKDYSNqyqYIATQGPVSNTLVD----FWRLIWQERSAIIVMITNIIEEGKMKCQ
...| | |. ||. .|. ||..|. | .. . |||| .|. . . .|||||| ..|. | |||..|.... .|||.|. .| |. ||
siallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekca
QYWPdsDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLE
|||| ... ||.|.||| .|..| |||||..... |.
qywp..gevtygdftvtllseehlddytvrtlllenld
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 733-865 | 1.1e-38 | 127.9 | In-house | 3-132 (250) | alignment | ||
Range on Protein: 733-865
Range on HMM: 3-132/250.0
VGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCtnEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMkCQQYWPD
|. |.|| ||.|.|. .| |. | . .| |.. .|||| ... |... .||||||...|..||||....| |. |||.||. |..| ..||||
vakkpqnkeknryadiialdssrvvLekekgdkes..dyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPv
SDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLE
.. || |.| .... .|||.||. . .
ekaekyGdvtvsllskeefadytkrklklskak
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 733-868 | 7.8e-35 | 115.8 | In-house | 3-136 (245) | alignment | ||
Range on Protein: 733-868
Range on HMM: 3-136/245.0
VGLTPSNKLLNRFANIVVYDDNRITLRPMSGHKDCTneYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPD
|.| | || .||. .|. ||..|. | |..|. |.. ||||.|.. | ..|||||| ..|. ||||..|.... .|||.|. | |. ||.||||.
vallpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl
SDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVT
.... || |.||| .|..| |||||...|. |
gesltygdftvtllseehlddytvrtlevtnlgdde
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 734-847 | 1.1e-12 | 42.1 | In-house | 91-197 (244) | alignment | ||
Range on Protein: 734-847
Range on HMM: 91-197/244.0
GLTPSNKLLNRFANIVVYDDNRITLRpmsgHKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEgkmkcQQYWPDS
. |.| || . . .| ||. | . | |||| .. .|| || |...| .|||... . ..|.. . || ..|||||
afnpnnswknregaglpfdfnrvpls....kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpds
DTKDYG--PFSVTLSD
. .. .|||.|
eplewyeeditvtltd
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 735-862 | 5.1e-29 | 96.1 | In-house | 16-146 (270) | alignment | ||
Range on Protein: 735-862
Range on HMM: 16-146/270.0
LTPSNKLLNRFANIVVYDDNRITLRPMSGhkDCTNEYINACYIKDY-SNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDS
. .| |||.|.|. |..| ... | . .|||| |.. . ... .|||..||. .|| .|||.||.|.. |||.|.. |.|. ||..||| .
eaargkklnRyadiLPsPatRvrleelee..dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpae
DTK----DYGPFSVTLSDEQVLTDYTVRKMHVK
. .| .|. . |. . | .......
pkekvkledgkikvlalseekeegyiltrlrle
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 737-876 | 9.2e-23 | 75.4 | In-house | 26-166 (319) | alignment | ||
Range on Protein: 737-876
Range on HMM: 26-166/319.0
PSNKLLNRFANIVVYDDNRITLRpMSGHKDcTNEYINACYIKDYSN-QYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDT
.. | .|..|.| . |..|. | .| .||..| |.. | . . .|||.| . .. ||||..|. .| .|| .|.. | | .| .|.| ..|
vtskdksrvinvvPlPetrvvlq.rigddd.kdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtket
KD----YGPFSVTLSDEQVLTDYTVRKMHVKVLEQVTQRpdEVTH
| || . ||| . .| | . . .| ... | |.||
ldntslyGdilvtlkgrevkdryaistlllkrvdkeesr..elth
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 738-864 | 9e-36 | 118.3 | In-house | 2-126 (237) | alignment | ||
Range on Protein: 738-864
Range on HMM: 2-126/237.0
SNKLLNRFANIVVYDDNRITLRPMSGHkdctNEYINACYIKDYSN-QYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDT-
||. ||..|||.|| .|. |. . .||||.|.|.. .|||.|||. .. |||...|||. ..|||.| .|| ..|| .|||..|
enkiknrygnivaydhsrvvlkgagsg....sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqp
KDYGPFSVTLSDEQVLTDYTVRKMHVKVL
. || ..|.| .. ..||||| . . .
aaygvltvslkkkeefsdytvrslllskr
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 738-862 | 1.3e-26 | 88.0 | In-house | 41-162 (296) | alignment | ||
Range on Protein: 738-862
Range on HMM: 41-162/296.0
SNKLLNRFANIVVYDDNRITLRPMSGHKDCTneYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKmKCQQYWPDSDTKD
|. || ..| || ||. |. . |... |||| |. . . .|| |..|. .|. .||||...| . .|..|. . | ....||| ..
enreknrdvkvvPyDynRvvLekldGeeksd..YinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeq
YGPFSVTLSDEQVLTDYTVRKMHVK
||.. | . |. ... . |.....
ygeifveiveekqyanlkirtfklt
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 738-837 | 7e-24 | 79.2 | In-house | 32-129 (297) | alignment | ||
Range on Protein: 738-837
Range on HMM: 32-129/297.0
SNKLLNRFANIVVYDDNRITLRPMSGHKDctneYINACYIK--DYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDT
| ||. .|. .||.|. |. .| |||| |. | ....|| .|||.|.|. |||.|.... .|||.... |.|. || |||...
sslrknryrdilatddtrvkllrviterd....yinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvq
KD
.
er
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 738-846 | 1.4e-16 | 55.3 | In-house | 34-139 (285) | alignment | ||
Range on Protein: 738-846
Range on HMM: 34-139/285.0
SNKLLNRFANIVVYDDNRITLrpmsghKDCTNEYINACYIKDY-SNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDS--D
.| |||.|.. . .. |. | |. .|| | ... .| ||.||||. .|| |||..|.||. | ..|. ..| | || |.|. .
anpdlnryadvrcieetrvvl......knhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
TKDYGPFSVTLS
.| . .||.
vvkfgkyeitlt
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 739-866 | 1.6e-37 | 124.5 | Pfam-A | 1-128 (235) | alignment | ||
Range on Protein: 739-866
Range on HMM: 1-128/235.0
NKLLNRFANIVVYDDNRITLrpmsgH-----KDctneYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWP--
|| ||. .|..||..|. | . .| |||| |.| |... ..||||||...|. ||||..|||.. .|||.|. |.|. ||.||||
nkkknRykdilpydktrvkl.....kgsegpsd....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpee
DSDTKDYGPFSVTLS-DEQ-VLTDYTVRKMHVKVLEQ
..... || ..|.| .|. ..||.||...| ..
eeesltygdikvelkekekedekeytlrklelkkkke
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 739-866 | 1.6e-37 | 124.5 | In-house | 1-128 (235) | alignment | ||
Range on Protein: 739-866
Range on HMM: 1-128/235.0
NKLLNRFANIVVYDDNRITLrpmsgH-----KDctneYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWP--
|| ||. .|..||..|. | . .| |||| |.| |... ..||||||...|. ||||..|||.. .|||.|. |.|. ||.||||
nkkknRykdilpydktrvkl.....kgsegpsd....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpee
DSDTKDYGPFSVTLS-DEQ-VLTDYTVRKMHVKVLEQ
..... || ..|.| .|. ..||.||...| ..
eeesltygdikvelkekekedekeytlrklelkkkke
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 739-869 | 1.7e-35 | 117.3 | In-house | 8-133 (239) | alignment | ||
Range on Protein: 739-869
Range on HMM: 8-133/239.0
NKLLNRFANIVVYDDNRITLRPMSghKDCTNEYINACYIKDYSNQ-YQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKd
|| ||.|||| || .|. | .| .| ..|||| |..|| |||||| |. . ||||..|||| ..|||.| .|| | ||.|||||| .|
nkaknryanivtydhsrvvlekls..ndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk.
YGPFSVTLSDEQVLTDYTVRKMhvkVLEQVTQ
| . ||| .|..|| .| . |. || |
ycnlrvtlrktevfadyiirtf...vmsqvgq
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 739-869 | 1.8e-35 | 117.2 | In-house | 7-132 (239) | alignment | ||
Range on Protein: 739-869
Range on HMM: 7-132/239.0
NKLLNRFANIVVYDDNRITLRPMSghKDCTNEYINACYIKDYSNQ-YQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKd
|| ||.|||| || .|. | .| .| ..|||| |..|| |||||| |. . ||||..|||| ..|||.| .|| | ||.|||||| .|
nkaknryanivtydhsrvvlekls..ndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk.
YGPFSVTLSDEQVLTDYTVRKMhvkVLEQVTQ
| . ||| .|..|| .| . |. || |
ycnlrvtlrktevfadyiirtf...vmsqvgq
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 739-836 | 2e-15 | 52.3 | In-house | 1-77 (182) | alignment | ||
Range on Protein: 739-836
Range on HMM: 1-77/182.0
NKLLNRFANIVVYDDNRitlrpmsghkdcTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITniieegkmkCQQYWPDSDTK
|. .||. .|. || .| . |||| .. . . ..|||||| .|. ||.|...... .||..| . .|||. ..
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpeller
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 739-832 | 1.5e-11 | 38.9 | In-house | 43-130 (288) | alignment | ||
Range on Protein: 739-832
Range on HMM: 43-130/288.0
NKLLNRFANIVVYDDNRITLRpmsghkDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPD
| .|. |. | |. | | .. ||.| . .. . | .| |. |. .|... .. |||.....| || | ..|.|
nptrdryenlprcditrvkls......ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPs
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 739-826 | 1.8e-08 | 28.3 | In-house | 34-118 (332) | alignment | ||
Range on Protein: 739-826
Range on HMM: 34-118/332.0
NKLLNRFANIVVYDDNRITLRPMSGHKDctneYINACYIKDYSNQYQYIATQGPVSN-TLVDFWRLIWQERSAIIVMITNIIEEGKMKC
| .|| . ..| .|. | | |. | . || .. ||.. || .| |. . | |||.. . . ..|... .| |. | |.
nmdmnriphlycfdhsrvelapqdgkdd....fynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrka
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 739-824 | 1.7e-06 | 21.9 | In-house | 47-123 (303) | alignment | ||
Range on Protein: 739-824
Range on HMM: 47-123/303.0
NKLLNRFANIVVYDDNRITLrpmsghkdCTNEYINACYIkDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKM
| |||..... | .. | . || | |. . . . | || |.| | |||..| ... .... | |.
nmdknrfvdvicldhskvkl........sdssyihasyl.eldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydkl
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 740-876 | 1.6e-33 | 111.0 | In-house | 29-165 (274) | alignment | ||
Range on Protein: 740-876
Range on HMM: 29-165/274.0
KLLNRFANIVVYDDNRITLRPMSGHKDcTNEYINACYIKDYSNQY-QYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTK--
. ||. .|. . |..|.. |.... .|||| ||| |... |.|||||..||. ||||.|.||.. .|||.|.. |. . ||..|.||.
qtknryktilPnensrvllesessede.dssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyei
--DYGPFSVTLSDEQVLTDYTVRKMHVKVLEQvTQRpdeVTH
|| .... .. ||.|||. .| ||. ... |.|
serygdveikvekiverndysvrklvlkyler.ers...vkh
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 740-883 | 6.4e-14 | 46.4 | In-house | 44-176 (312) | alignment | ||
Range on Protein: 740-883
Range on HMM: 44-176/312.0
KLLNRFANIVVYDDNRITLrpmSGHkdcTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWpdSDTKDYg
| |||. || ..| |.|| .| | || | ..| .. ....||||. || . ||.| |. |.... ..|.| || .| || .
kdlnrypniqcwdrgrftl...agd...enfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyi..sdivgf.
pfsVTLSDEQVLTDYTV-RKMHVKVLEQVTQRPDEVTHNIASQNN
| | | .| |.| .. | ...|.| | . . |.
...vdledhrvyteycteieiggkskdkithrvlkvvvkatgqes
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 741-833 | 1e-14 | 48.9 | In-house | 57-145 (305) | alignment | ||
Range on Protein: 741-833
Range on HMM: 57-145/305.0
LLNRFANIVVYDDNRITLRPMSghkdcTNEYINACYIK-DYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDS
||.... . | . . | | .|| | |. . ..|..|||. .|. .|| .. |.. |||. . .| ||.|| |||| .
tknryqdvpcqdqsavkldkps.....psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaa
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 742-865 | 1.9e-29 | 97.4 | In-house | 41-163 (287) | alignment | ||
Range on Protein: 742-865
Range on HMM: 41-163/287.0
LNRFANIVVYDDNRITLrpmSGHKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDT-KDYGP
||.|... .||.|. | | . . .|||| |. | .. ..||.|||.. |. ||||.....||| ....| .||...|| .|||. . |
knryadvlPiddtrvll...saegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGG
FSVTLSDEQVL-TDYTVRKMHVKVLE
.||.| | ... .|.|| . . ||
ysvvlldydikePeygvralrlidle
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 743-859 | 4.5e-21 | 69.7 | In-house | 60-171 (290) | alignment | ||
Range on Protein: 743-859
Range on HMM: 60-171/290.0
NRFANIVVYDDNRITLRpmSGHkdcTNEYINACYIKDYSNqyQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTK--DYGP
||. ..| | |. |. |. .|. | |.| .| |||.. .| .|.||.. ||. | |||. ..||.|| ||.||.|. . . .|
nrykdvvcndktrvilk..dGy...dGdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGe
FSVTLSDEQVLTDYTVRKM
..|. | |. . ...|.
itvlcseeddkdaniikkt
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 743-819 | 2.6e-09 | 31.1 | In-house | 41-120 (347) | alignment | ||
Range on Protein: 743-819
Range on HMM: 41-120/347.0
NRFANIVVYDDNRITLRPMS---GHKDCTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNII
|| . . |. |. | | .. | .. |||| .|| . .|| || |. .|. |||... . . .| | . |
nrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepi
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 745-862 | 8.7e-10 | 32.5 | In-house | 57-173 (332) | alignment | ||
Range on Protein: 745-862
Range on HMM: 57-173/332.0
FANIVVYDDNRITLRPMSGHKDctnEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSD--TKDYGPFS
.|| || . . | . .. |||| .. .|| | . . . ||... ...| ||.. . .|.. | ..|.|| ..| .
vvkivpydrylvrltssqlnrl...GyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGild
VTLSDEQVLTDYTVRKMHVK
|. . . .|.. ..
verkefvkrniletrllels
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 751-836 | 9.5e-09 | 30.6 | In-house | 2-76 (178) | alignment | ||
Range on Protein: 751-836
Range on HMM: 2-76/178.0
YDDNRITLRPMSGHKDctNEYINACYIKDYsnqyQYIATQGPvsntlVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTK
.|..| | ...|. .||||..| .. |.....| .|...|.... ||..|. .| |..|| .|||..
ldrtrvllsnlegler..sdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeagi
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 752-885 | 2.5e-08 | 28.4 | In-house | 31-171 (290) | alignment | ||
Range on Protein: 752-885
Range on HMM: 31-171/290.0
DDNRITLRPMsgHKDCTNEYINACYIKdYSNQYQYIATQGPVSN-------TLVDFWRLIWQERSAIIVMITNIIEEGKM----KCQQYWPDSDT--KDY
..|. |. | ...|| | ... ..| . |.|| | . |. .|| .. ||.. .||. . |. . |..| |.| .
eatrvvLkgy..gkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkf
GPFSVTLSDEQVLTDYTVRKMHVKVLEQvtqRPDEVTHNIASQNNDR
. ..| . | .|.. || .. .. |||. .. |..
kgltvkCkskekeddvetRelvvkfdde...eeftvtHsllkgWnkl
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 754-846 | 3.7e-09 | 31.0 | In-house | 8-85 (130) | alignment | ||
Range on Protein: 754-846
Range on HMM: 8-85/130.0
NRITlrpmsghkdcTNEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEgkmkcQQYWPDSDTKDYGPFSVTLS
.|. |.|||| .. . .|. || |...| .|||... . ..|.. . || ..|||||. .. ....
srlq..........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivt
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 769-865 | 2.9e-17 | 58.7 | In-house | 4-114 (272) | alignment | ||
Range on Protein: 769-865
Range on HMM: 4-114/272.0
NEYINACYIKDYsnqYQ------YIATQGPVSNTLVDFWRLiWQERSAIIVMITNIIEEGKMKCQQYWP------------DSDTKDYGPFSVTLSDEQV
. |||| ... | .. .....|| .| ||||| .... ||.... | |. || .||| . | || ..||| |..
sgyiNardvggy...grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseel
LTDYTVRKMHVKVLE
|.||..|.. .. |
lldyilrellltlll
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 769-840 | 2.6e-12 | 42.3 | In-house | 12-79 (176) | alignment | ||
Range on Protein: 769-840
Range on HMM: 12-79/176.0
NEYINACYIKDYsnqyQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGP
|||| .| . .||||||. .|| ||........ ..|..|. .| |. || .|||. . ..
ldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqy
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 769-850 | 1.3e-11 | 40.0 | In-house | 2-61 (174) | alignment | ||
Range on Protein: 769-850
Range on HMM: 2-61/174.0
NEYINACYIKDYSNQYQYIATQGPVSntlvdFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDsdtkdygpfsvtlsdeqV
. |||| ... . .||.||| . ||........ ..|| .. .| |. || .|||.
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.................l
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 769-832 | 4.2e-11 | 38.4 | In-house | 5-75 (172) | alignment | ||
Range on Protein: 769-832
Range on HMM: 5-75/172.0
NEYINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIieegkmkcqQ----------------YWPD
. |||| |.. | ..|||||| .||| ||||..... .||..|. . .|||
sdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel.........lydpellerlgiqylylpwpD
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 769-835 | 1.1e-08 | 30.3 | In-house | 3-58 (151) | alignment | ||
Range on Protein: 769-835
Range on HMM: 3-58/151.0
NEYINACYIKDYsnqyqYIATQGPVSntlvDFWRLIWQERSAIIVMITNIIEEGkmKCQQYWPDSDT
. |||. |. .. .....|| . ||..|.... ||.... | | .| .|.|. .
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelgi
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 771-868 | 2.1e-13 | 44.7 | In-house | 77-176 (301) | alignment | ||
Range on Protein: 771-868
Range on HMM: 77-176/301.0
YINACYIKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSD--TKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVT
| | .|. . ..||||||..|| ||| .. | |||... .|. . ||..| | . . | | |.... ..... . . | ...| .
PihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstg
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 777-857 | 1.2e-11 | 40.0 | In-house | 2-56 (152) | alignment | ||
Range on Protein: 777-857
Range on HMM: 2-56/152.0
IKDYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWpdsdtkdygpfsvtlsdeqvltdytvR
|. | .....|||||| .||| ||||.... .|||.|. | || || ||. .
idgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................q
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 779-868 | 2.4e-11 | 37.6 | In-house | 231-318 (440) | alignment | ||
Range on Protein: 779-868
Range on HMM: 231-318/440.0
DYSNQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEegkMKCQQYWPD-SDTKDYGPFSVTLSDEQVLTDYTVRKMHVKVLEQVT
||.. .|||| |. |..|||||. . | . |.|. .. . | ||| . . .|||.| . . || . .| |.|
gyskknafiatqmpldstvldfwrlvhdyristiimlnqlnd...ktcsiywpvntrsvtfgpftvghkgsenmnrvkvrtlelkykeevh
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 782-862 | 1.6e-11 | 38.7 | In-house | 3-85 (199) | alignment | ||
Range on Protein: 782-862
Range on HMM: 3-85/199.0
NQYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPD--SDTKDYGPFSVTLSDEQVLTDYTVRKMHVK
| .||||| |. .|. |||...|. | |||. . . . ||| | | || .||| . |||. . .
gqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitalilt
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 783-862 | 2.1e-11 | 38.4 | In-house | 3-84 (198) | alignment | ||
Range on Protein: 783-862
Range on HMM: 3-84/198.0
QYQYIATQGPVSNTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPD--SDTKDYGPFSVTLSDEQVLTDYTVRKMHVK
| .||||| |. .|| |||...|. | |||. . . . ||| | | || .||| . |||. . .
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitalilt
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 786-861 | 4.9e-06 | 20.8 | In-house | 39-105 (255) | alignment | ||
Range on Protein: 786-861
Range on HMM: 39-105/255.0
YiatqgpvsnTLVDFWRLIWQERSAIIVMITNIIEEGKMKCQQYWPDSDTKDYGPFSVTLSDEQVLTDYTVRKMHV
|. |.. | | .. .||... |||. ||..|.| . |... . .| .| ...
l.........tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtlei
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 854-1096 | 3.1e-23 | 77.2 | In-house | 13-262 (307) | alignment | ||
Range on Protein: 854-1096
Range on HMM: 13-262/307.0
YTVRKMHVKVLEQVTQRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLK--GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVM
|... . . . |. || . | |.|.|| .. |. |. .| | ||| | .. . | || |. |. || .|| |. . .| ...|
kgvqalvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvim
LCQENENDQEVCYQYWS--NGKLGEY-----NISLLNEEIHNAGYIERKIEVTNDN--KAGDKQQVKQYQITNWDSTGkmtNPQTILLVIEEMYRTQRKr
||. | . | ||| .|. . ||. | ... | |.||. . |.. . ....| .|| | ||. | |. . .. .
lckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrg...vpqinltainlleavryd.
gNTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQT
. .||||| |||| | . .| . . |. .... | |.. ..||
.tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqt
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 857-1096 | 1.9e-56 | 186.0 | In-house | 8-251 (283) | alignment | ||
Range on Protein: 857-1096
Range on HMM: 8-251/283.0
RKMHVKVLEQVTQRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFIN---GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLC
|.. .||.... . ... . |..|. || .. .| |..|| || | .|||||||| ||..| .||| ||. .| ..||||. |...||||||
nklfrevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmlt
QENENDQEVCYQYWS-NG--KLGEYNISLLNEEIHNaGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTiLLVIEEMYRTQRKRGNTSIVVH
. |. .. | ||| .| . ||. ..| .| .| .| ... . ... | .. . ||. .| . |. . . |. .. . |.. .. ||||
klqedlrikCsqyWPkrGsedyGeftvtlrkettsn.sfiikelllrvnssakstlllahyqvidWleygeqaiins.lvkfnkvislqteskkgPivvh
CSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
|| ..||.|.|.||...... .|| |.|||.|.| | |... |||
CstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqt
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 862-1097 | 7.1e-142 | 466.5 | In-house | 27-264 (287) | alignment | ||
Range on Protein: 862-1097
Range on HMM: 27-264/287.0
KVLEQVTQRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQE
.||||||||.|||||||||||.|.|||.|.|.||||||.||||||||||||||.||||||||||||||||||||||||.|||||||||||||||.|||.|
tvleqvtqredevthniasqnkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendee
VCYQYWSNGK---LGEYNISLLNEEiHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRS
||||||...| ||||||.||||| .||||||||.||.|.||||||||||||||||||||||.|.||||||||||||.|||||||||||||||||||||
vcyqyWpeeksvvlGeyniellnee.vnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrs
AMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|||||||||||||||||||||||||||||||||||||||
amfcaaattinkckteGviDvfqvlksqriqkpgsvqtv
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 862-1096 | 3.1e-38 | 126.3 | In-house | 13-244 (267) | alignment | ||
Range on Protein: 862-1096
Range on HMM: 13-244/267.0
KVLEQVTQRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQE
. ...... .. ||..|..||||.. || |. ||.|. . .|||| ...||| |.|||. . |. || .|...| |..|. ||.| . ...
elikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnir
VCYQYwSNGKLGEYNISLLNEEIHN--AGYIERKIEVTNDNKagDKQQVKQYQITNWDSTGKmtNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSA
. |. .|. .. . . | .|. |. ..| | .|. . | . .. . . | . || .||.||| ||||
lfwPP.kmgqakkyqdltvehslekeendyqiitlelkfkne..sahnvtlyyykkwnintn..nkpylkplfgilaknqlengnrPlvvacsdGvGrsG
MFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
| . . ... ||||| |.|. |. | |..| |.|
tflvidsqleraktegvsdifdflrkirsqriglvdt
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 862-959 | 8.4e-09 | 29.5 | In-house | 26-121 (303) | alignment | ||
Range on Protein: 862-959
Range on HMM: 26-121/303.0
KVLEQVT-QRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKgeHPDYINAVFINGYKEKKAfIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENEND
. .|.|. | .|..| .| |.||. . . | .| | || | ... .||| |... |. || .||.|| ...| ...| ..| |
nefekvvsylppsvsknqfvknmdknrfvdvicldhskvkls..dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseyd
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 863-1070 | 2.7e-19 | 64.2 | In-house | 29-255 (418) | alignment | ||
Range on Protein: 863-1070
Range on HMM: 29-255/418.0
VLEQVtQRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEkKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENEN
.||. | | . .| .|| . || . || || | ||||| .|.| | || .. |. || .||.|. . . |||| .|.||
llees.vgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsresen
DQEVCYQYWSNGKLGEyNISLL--NEEIHNAgYIERKIEVTNDN------------KAGDKQQVKQYQITNWDSTG--KMTNPQTILLviEEMYRTQ---
. | .|| . || ..|. .|. . | .|| .| |. ... ||| | |.| || . |
crikcdrywpeqigge.qfsiygngnevfgt.ysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqll..hsitnrqnqi
--RKRGNTSIVVHCSDTVGRSAMFCAAATTINK
| |.|||| |||. ||.| ..|
ipssdrnvpiivhcsagvgrtgtfctavimmkk
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 864-1096 | 7.6e-56 | 184.5 | In-house | 36-275 (298) | alignment | ||
Range on Protein: 864-1096
Range on HMM: 36-275/298.0
LEQVTQRPDEVTHNI--ASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENE
|..|... .| .... ...|...|| . .. | || |. |. |||||.|...||...|||... |. .| .||.|. ......|||| . .|
lnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnlee
NDQEVCYQYWSN---GKLGEYNISLLNEEiHNAGYIERKIEVTNDNKAgDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDT
|. . .|| . . || ..|||..| . | .| ||..|.. ... ....|.| . |.| . | .| ...| ..... ..|.. ||....|.||.
ldktkyhkywPdegketygeitvsllske.efadlivrklkvskkkee.kerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaG
VGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
|||| |.| . ... |.| |.|||||.| |...||.|||
vgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqt
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 866-1097 | 3.2e-112 | 369.1 | In-house | 30-269 (290) | alignment | ||
Range on Protein: 866-1097
Range on HMM: 30-269/290.0
QVTQRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLK--GEHPD----YINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENEND
...... .||....|.|. .|| ......|..|..|. ..|.| ||||..|.||||||..|....|..||...|||.|....||.||||....|..
dsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieeg
QEVCYQYWSNG---KLGEYNISLLNEEIHNaGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVG
...|.|||.. ..||..| |||||..| .|||||.||.|.|.||.||.|.||||||||||||.||||||||||||||.|||||||||||||||||||
kvkCqqYWpdsdtkaygefsikllneetln.eyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvg
RSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|||.|||||||||||||||||||||||||||||||||||||
rsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtv
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 866-1096 | 5.4e-42 | 138.7 | In-house | 31-272 (563) | alignment | ||
Range on Protein: 866-1096
Range on HMM: 31-272/563.0
QVTQRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLK---GEH--PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQ
..... ...| . .| .|| . .. |. || |. |.. ||||| .|.||. .||||.. |. .|. ||.|| ..||. |||. . .|. .
etiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergr
EVCYQYWSNGK---LGEYNISLLNEEIHnAGYIERKIEVTN-DNKAG----DKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKrGNTSIVVHCS
. | .|| . . .|. .. | .||.. | | .|.. . | |.. ....|.||. |.| .| . . | .. ..... ||||||
rkcdvYWPkdesetygalqvtlieeevl.alytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaanka.eaGPivvHcs
DTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
|||. .... | ... ..| ...||..|| | |.. |||
aGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqt
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 866-1096 | 7.6e-33 | 108.5 | In-house | 14-256 (290) | alignment | ||
Range on Protein: 866-1096
Range on HMM: 14-256/290.0
QVTQRPDEVTHNI--ASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVC
.... ...... .|...|| | | |. |. .. ||||| ... . |. .|.. |. ||. ||.|. ... |.||| . |..| |
dirkeasdfptreaklpenrnlnryrdvspydhsrikleradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikc
YQYWSNGKL------G--EYNISLLNEEIHNAgYIERKIEVTNdNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQR-KRGNTSIVVHCSDT
.||| .|. .... |..||... |. |..|..| |. . ... .. | | | |.. | . .. .. .. |.|||
aqywPqgeeekellledtklkvkliseerksy.ytvrllelen.lktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaG
VGRSAMFCAAATTIN---KCKTEGVIDVFQVLKSQRIQKPGSVQT
.||| || . | . | . .|. .|| | .. | .||
iGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqt
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 866-1029 | 1.6e-12 | 41.8 | In-house | 16-184 (319) | alignment | ||
Range on Protein: 866-1029
Range on HMM: 16-184/319.0
QVTQRPDevthNIASQNNDRNRLNQFLP--PDNYRVPLKGEHP--DYINAVFINGYKEKKA-FIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQ
|. | | .. .|..|. . .| . . .. .|... |..| .. ||.. .. .| |. .. ... .||... ... || |.. |.
qliarad....evPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGi
EVCYQYWSNGK-------LGEYNISLLNEEIHNAgYIERKIEVTNDNKAgDKQQVKQYQItNWDSTGKMTNPQTIL
.|| .|. . |.. ..| . |... |. . . . .| ... | .| .. .......
kvcaeylPtketldntslyGdilvtlkgrevkdr.yaistlllkrvdke.esrelthywy.kwleaevPaeeaali
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 868-1096 | 4.6e-57 | 189.4 | In-house | 41-289 (307) | alignment | ||
Range on Protein: 868-1096
Range on HMM: 41-289/307.0
TQRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKG-----EHPDYINAVFI--------NGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQ
.. ..| .. .| |.|| .|| |. || |. |. ||||| .. .||. |..||.. .|. .| .||.|. . .||.||||..
vfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmlte
ENENDQEVCYQYWSNG----KLGEYNISLLNEEIhNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKR-GNTSIVV
. |...| |.|||.. |.. . ||.||. .||. |..|||. .. | .|.... |.| .| ......| |||. . ... ... ..|
lvelgrekcaqywPdegeeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlV
HCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQT
|||. |||...|.|| . . ..||. .|.....| | |.||.||.
HCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqn
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 869-1096 | 1.2e-64 | 213.4 | In-house | 35-268 (305) | alignment | ||
Range on Protein: 869-1096
Range on HMM: 35-268/305.0
QRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEHP--DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQY
. . .|... |.....|.. .. |..| ... | ... ||||| ...|||.||..|.| .|. || ..||..| . |. ||||.. |.... |.||
eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqY
WSNG-----KLGEYNISLLNEEiHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMF
| . ..||... | .|. . ..|||||........ ....| |||.|.| | . . ..| .|... ..|.| .....||||..|||. .|
Wpesktekkefgefsvelksek.tasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvf
CAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.| ....|.|.|.|||.||| | .... |||
iavdialerlkkEevvdvfevlkqlRskrmkmvqt
|
|||||||||
| DSPc_SM00195 | 869-1096 | 2.7e-57 | 189.5 | In-house | 15-247 (263) | alignment | |||
Range on Protein: 869-1096
Range on HMM: 15-247/263.0
QRpdEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCY
.. |.|... ..|...|| ...|| |. || || |. ||||| .|.|...||..|.. |. .| . ||.|. ...|. ||||..|.||..| |.
pk..etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcd
QYWSNG-----KLGEYNISLLNEEIHNAGYIERKIEVTNDNKaGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRgNTSIVVHCSDTVGRSA
.|| . . |.... | ..|.... .| |..|.|...| ....|.|||..|| | ... .| ...... .... .. ||||||. |||..
rywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtg
MFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.|... . ..|...| .|.|...|. | |.||.|||
tfvtidiilskleeekkvdifeivkelRkqRpgmvqt
|
|||||||||
| PTPc_SM00194 | 869-1096 | 2.7e-57 | 189.5 | In-house | 15-247 (263) | alignment | |||
Range on Protein: 869-1096
Range on HMM: 15-247/263.0
QRpdEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCY
.. |.|... ..|...|| ...|| |. || || |. ||||| .|.|...||..|.. |. .| . ||.|. ...|. ||||..|.||..| |.
pk..etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcd
QYWSNG-----KLGEYNISLLNEEIHNAGYIERKIEVTNDNKaGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRgNTSIVVHCSDTVGRSA
.|| . . |.... | ..|.... .| |..|.|...| ....|.|||..|| | ... .| ...... .... .. ||||||. |||..
rywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtg
MFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.|... . ..|...| .|.|...|. | |.||.|||
tfvtidiilskleeekkvdifeivkelRkqRpgmvqt
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 869-1096 | 9.2e-57 | 188.1 | In-house | 30-261 (317) | alignment | ||
Range on Protein: 869-1096
Range on HMM: 30-261/317.0
QRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCY
. .|. .. . .| |.|| .|| |. || |. . ||||| ...|...|..||.. .|. || .||.|. . .|| ||||... |...| |.
lkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrekca
QYWSNG---KLGEYNISLLNEEIhNAGYIERKIEVTNDnKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMF
|||..| . |.. . ||.|| .||.. |..||... . ... .|.... |.|. | .|...| .|.. . .. .... ..||||. |||...|
qYwplgetltygdftvtllseee.lagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVHCsaGvgRtGtf
CAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.|| . .. ...|| .||....| | |.||.|||
iaaylmleqlekeggvdveeavkelreqRpgavqt
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 869-1096 | 1.1e-54 | 180.2 | In-house | 29-278 (301) | alignment | ||
Range on Protein: 869-1096
Range on HMM: 29-278/301.0
QRPDEVTHNiaSQNNDRNRLNQFLPPDNYRVPLKG------EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEV
... .|... ..|. || .. . |. |. || . .|||| .|.||.|||.||.|..|| .| ..||..| . ...|||.....|. ..
dksctvgls..eenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtksk
CYQYWSNGKLGEY-----NISLLNEE----------------IHNAGYIERKIEVTNDNkagDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRK
|.|||.|.. .. .. | || | ||||||..|..|. . ..| |.|.|.| | . .|.|.| ||... .|.|
ceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk...sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqk
RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
| .||||||||.|| ..|. .. || |||.||||| |. | .||| |.|
igggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtT
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 869-1096 | 8.8e-53 | 175.0 | In-house | 43-274 (297) | alignment | ||
Range on Protein: 869-1096
Range on HMM: 43-274/297.0
QRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKG-----EHPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQeV
. ... .. .| |.|| .|| |. || ||. .. ||||| ...||. ...||.. |. .| .||.|. . .||.||||....|...
slkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.k
CYQYWSNG--KLGEYNISLLNEEIhNAGYIERKIEVTNdnkAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSA
|.|||.. . |.. . ||..| ..||. |..|||| | .|...| |.| | .....| ..|.. . ... ... ..||||. |||..
caqywpeeggtygdftvtllkveh.ldgytvrtlevtn...ngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtG
MFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.|.|| . .. ...|| .||....| | |.||.|||
tfiaaylmleqlekeggvdvleavkelreqRpgavqt
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 869-1096 | 9.7e-52 | 171.5 | In-house | 32-262 (278) | alignment | ||
Range on Protein: 869-1096
Range on HMM: 32-262/278.0
QRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCY
. .|. .. . .| |.|| .|| |. || |. . ||||| ...||. ...||.. |. .| .||.|. . .|| ||||... |.... |.
fkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgrvkca
QYWSnG---KLGEYNISLLNEEIhNAGYIERKIEVTNdNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMF
|||. | . |.. . ||.|| ...|. |..|||| .. | ...| .|. ..| | ......| .... . .. |. ..||||. |||...|
qYwp.ggsltygdftvtllkeeh.lddytvrtlevtn.lgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtf
CAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.|. . .. ..|| .|.....| | |.||.|||
ialyllleqlekeggvdleeavkelreqRpgavqt
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 869-1096 | 1.5e-51 | 170.8 | In-house | 20-257 (278) | alignment | ||
Range on Protein: 869-1096
Range on HMM: 20-257/278.0
QRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPlkgehpDYINAVFINGYkeKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS
|.|.|... | |.|| ..|| |. || ||||| .|.|| .|.||.. |. .|. .||.|. . ..|.||||... |...| |.|||
gipseitpalylgnldknRykdilpydhsrVk......dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywp
NGK---LGEYNISLLNEEIHnAGYIERKIEVTND---NKAGDKQQVKQYQITNWDSTGKMTNP--QTILLVIEEMYRTQR------------KRGNTSIV
.|. |.. . ||.||.. |. |...||| . . . |.......|. | ..| . .| ..|.. . .. ... ..
eggsltygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvl
VHCSDTVGRSAMFCAAATTINKCktEGVIDVFQVLKSQRIQKPG-SVQT
|||| |||.....|| . . . ||..|.....| | |.|| .||.
VHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqn
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 869-1096 | 2.1e-41 | 136.9 | In-house | 34-264 (288) | alignment | ||
Range on Protein: 869-1096
Range on HMM: 34-264/288.0
QRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCY
.. ..|| ..|...|| .. || | || ||. . ||||| .|.|.|.||..| . .|. .| .||... ..... |||| . |.... |
ektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCe
QYWSNGKL----GEYNISLLNEEiHNAGYIERKIEVTndnKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRgNTSIVVHCSDTVGRSAM
.|| ... |. .. |.... . ...||... | ... ...||| . | .| . . .| ... . .. . |.||||. |||.
eYWPdadkpknyGsvtvtlvesk.eledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgt
FCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
| |. . |.. ..| .|||. ... | |.. |||
FialdalidaveeedyiDvagtvaklRkqRallvqt
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 869-1094 | 7e-19 | 62.9 | In-house | 22-253 (285) | alignment | ||
Range on Protein: 869-1094
Range on HMM: 22-253/285.0
QRPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFIN-GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYW
| ..|. | | || . .. || || ||| | .. |.. ..| .. |. .| .||.|| . ... ..||| | | | |.
ymppnctytayeanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyy
SN-----GKLGEYNISLLN-EEIHNAGYIERKIEVTNDNKAGDKQ-QVKQYQITNWDSTgkmTNPQTILLVIeEMYRTQRK--RGNTSIVVHCSDTVGRS
. |.|.|.|.| . .| || | . |.| . | . ... |. | |. .| |.|. .| .. |.|||| |||.
peklgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdq...lapedarpmi.elykwvkkvnpkekpicvhcsagvgrt
AMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSV
| | . . . |....... | . .|
atfvgidyatirimenpniemldivremramrfqav
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 869-1028 | 4.6e-13 | 43.4 | In-house | 81-242 (244) | alignment | ||
Range on Protein: 869-1028
Range on HMM: 81-242/244.0
QRPD--EVTHNIASQNNDRNRLNQFLPPDNYRVPLK-GEH-PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQevcy
||| . . .|. .|| || | |||| | |||| |. .|... |. .|. .||||. .| | .|.| .|.|.
irpdpsvmkdafnpnnswknregaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeede....
qYWSNGKLGEY---NISLLN---EEIHNAGYieRKIEVTNDNKaGDKQQVKQYQITNWDSTGKMTNPQTI
|| . . |. .|.. .|..| ..|. | . .| . .||.|| | | | |
.ywpdseplewyeeditvtltdrdefknika..snleiesdmn.eshqaltmfqisnwpsdgttpndhfi
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 870-1090 | 9.8e-16 | 52.2 | In-house | 40-269 (310) | alignment | ||
Range on Protein: 870-1090
Range on HMM: 40-269/310.0
RPDEVTHNIASQNNDRNRLNQFLPPDNYRVPLK---GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQY
. .|.. .. .|| . . |. || || . ||| | ... ...|| .. |. | .||.|| . .|..||. |. . | |
qdssltyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgy
WSNGKLGE-Y---NISLLNEEIHNAGYIERKIEVTNDNKAGDKQQVK--Q--YQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNtsIVVHCSDTVGRS
| . | | .. |.| .. . . || |.| . . .. .| . |. . . .| . | ||||| ..|
wpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrllaqvrhgp..cvvhcsagkdrl
AMFCAAATTINKCKTEGVIDVFQVLKSQRIQK
. .| .|.| . .|. .| . ..
yvvvalklkidkldrglkvdaeevktellksr
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 871-1097 | 9e-61 | 201.2 | In-house | 57-285 (308) | alignment | ||
Range on Protein: 871-1097
Range on HMM: 57-285/308.0
PDEVTHNIASQNNDRNRLNQFLPPDNYRVPLkGEHPDYINAVFINGY--KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYW-
. | .. .| |.|| .|| |. || | .|. ||||| ...|| | ...||.. .|. || .||.|. . ||. ||||... ||..| |.|||
lleysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwp
-----SNGKLGEYNISLLNEEIhNAGYIERKIEVTNDNKAgDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQrkrGNTSIVVHCSDTVGRSAMFC
. . | . . ||.||. ...|. |..|.|| .. . .|.... ||| | ..|. .| .|.. ... .. ||||||. |||.. |.
lelgggsleygkftvtllseev.lddytvrtleltnlgdg.esrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfi
AAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|. . .. ..|| .|||...| | |.||.|||.
aldllleqlekeggvdvfeavkklReqRpgmvqtp
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 871-1096 | 1.1e-58 | 194.3 | In-house | 27-257 (273) | alignment | ||
Range on Protein: 871-1096
Range on HMM: 27-257/273.0
PDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG
. . .. . .| |.|| .|| |. || |.... ||||| ...||. |..||... |. || .||.|. . ||. ||||... |...| |.|||..
lltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekcaqYwple
------KLGEYNISLLNEEIhNAGYIERKIEVTNDNKAGdKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCA
. |.. . ||.||. ...|. |..|.|| . . .|.... |.| | .... .| ||.. ..... .|. .|||||. |||...|.|
ggelsltygkftvtllseet.kddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfia
AATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. . .. ..|| .||....| | |.||.|||
ldllldqlekeggvdvleavkllrsqRpgmvqt
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 871-1096 | 2.9e-49 | 162.9 | In-house | 37-268 (319) | alignment | ||
Range on Protein: 871-1096
Range on HMM: 37-268/319.0
PDEVTHNIASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQY
.|.... .|...|| .. |. |. || |. | ||||| ||.||.|...|| . .|. || .||.|. .... .|||.. .|. . . .|
ndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkky
WSNGKLGEYNISLL--NEEIHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAA
|.. . || .. .|| . ..|| ||... . . . .||..| |.| . .. ...| ..... ....| . ||||||. ||| |..
wpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivl
ATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.... | |||.|||.. . |.|.. ||.
damlervkeegvlDvfstvsrlRtqRnimvqr
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 872-1097 | 1.2e-58 | 194.2 | In-house | 39-272 (288) | alignment | ||
Range on Protein: 872-1097
Range on HMM: 39-272/288.0
DEVTHNIASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYW
.... . .| ..|| .|| |. || |. |. ||||| .|.||. |..||... |. || .||.|. . ||. ||||... |...| |.|||
ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYw
SNG---KLGEYNISLLNEEIhNAGYIERKIEVTNDN---KAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMF
..| ..|.. . ||.||. ...|. |..|||| . . | ...|.... ||| | ..|. .| ...... .. |. .|||||. |||...|
plggsltygditvtllseev.lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtf
CAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
.|. . .. ..||..||....| | |.||.|||.
ialdllleqlekeggvdvleavkrlreqRpgmvqtp
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 872-1096 | 2.6e-20 | 67.6 | In-house | 30-256 (288) | alignment | ||
Range on Protein: 872-1096
Range on HMM: 30-256/288.0
DEVTHNIAS---QNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS
.| . .|.. .| |.| .. | || |. . ||.| . | |. .| |..|. | ..|||. . .| |||||. | .| .|.
neasidiidsfianptrdryenlprcditrvklsddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfP
NGKLGEYNISLLNEEI-HNAGYIERKIEVT--NDNKAGDKQQ-VKQYQITNWDSTGKMTNPQTILLVIEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAA
. . | | . .. |.. ..|. . .| |.... ||. . .|| | | .. | ..| . | . ||||.| |||.. .
sklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlili
ATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.. . . . . ..|.. | .. ..||
lialeslrlddflgirsllaklreerfkaiqt
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 872-982 | 2.7e-13 | 44.4 | In-house | 38-165 (350) | alignment | ||
Range on Protein: 872-982
Range on HMM: 38-165/350.0
D-EVTHNIasQNNDRNRLNQFLPPDNYRVPLK------------GEHPDYINAVFINGY----KEKKAF--IIAESPMFNTARNFWKMIDDRNVTAIVML
| .... . . .|| .. || . || || . ||||| ... . . | | . .|. .| .|.|.| .|. |..|
DvilseGv..elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsl
CQENENDQEVCYQYWSNGKLGEYNISLLNE
.. |.. | ||.|| .|. .... | .
tsdvelnlekcyrYWqegsydditvklask
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 873-1097 | 1.3e-59 | 197.3 | In-house | 30-263 (297) | alignment | ||
Range on Protein: 873-1097
Range on HMM: 30-263/297.0
EVTHNIASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG--
. .. . .| ..|| .|| |. || |..|. ||||| ...||. |..||... |. || .||.|. . ||| ||||... |.. | |.|||..
slsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleeg
---KLGEYNISLLNEEIH-NAGYIERKIEVTNDnKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAA
. |.. . ||..|.. ...|. |..|||. . |.. .|.....|.|. | ..|...| ||.. . ... ... ..||||. ||||..|.||
esltygdftvtllsvevvllddytlrtlevtdt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaad
TTINKCK---TEGVIDVFQVLKSQRIQKPGSVQTV
. .. . .|| .|.....|. | |.||.|||.
lmlqqledklkeggvdileavkklReqRpgavqtl
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 873-1097 | 4.4e-59 | 195.5 | In-house | 19-260 (284) | alignment | ||
Range on Protein: 873-1097
Range on HMM: 19-260/284.0
EVTHNIASQNNDRNRLNQFLPPDNYRVPLKG-----EHPDYINAVFINGY-----KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEV
.... .. .| ..|| ..|| |. || || |. ||||| ...|| . ||.||.. |. || .||.|. . ||. ||||... ||..|
slsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengrek
CYQYWSNGK----LGEYNISLLNEEIhNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRK-RGNTSIVVHCSDTVGR
|.|||.. . .|.. . ||.||. . .|. |..|.|| . | .|.....|.| | ..|. .| .... . ... |. ||||||. |||
caqYwplegevltygdftvtllseev.kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgR
SAMFCAAATTINKCKTEG---VIDVFQVLKSQRIQKPGSVQTV
...|.|. . .. ..|| ..||....| | |.||.|||.
tGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtl
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 873-1096 | 1.2e-56 | 187.6 | In-house | 39-266 (564) | alignment | ||
Range on Protein: 873-1096
Range on HMM: 39-266/564.0
EVTHNIASQNNDRNRLNQFLPPDNYRVPLK----GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS
.... ...| .||... .. |. || |. | ||||| ||.||...||.| . |. .| ..||.|. ..|.. |||| . .|.... | .||
tweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWP
NG---KLGEYNISLLNEEiHNAGYIERKIEVtNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAA
. . ||. ..| .|| . | |. |.... ...| ....|.|.. |.| ..| .......| .|... ... .... |||||| |||. .|..
ekgtetygeltVtleeee.eladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfivid
TTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
... |.|...|..|..| | |.. |||
amlerikeektvDiyqyvkalrkqRnamVqt
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 873-1096 | 3.3e-52 | 172.5 | In-house | 37-265 (318) | alignment | ||
Range on Protein: 873-1096
Range on HMM: 37-265/318.0
EVTHNIASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS
.. . . |. .|| . |. |. || |. | ||||| .|.||..|||.| | .|. .| ..||.|. ..| . |||| ||.|. .. . .||
tslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWP
NGKLGEYNI--SLLNEEIHNAGYIERKIEVTNdNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAAT
. . .|. |.||.. . |. |...||. .. ...||.||..|.| .| ... ..| .. . ..|.| |.. |||||| ||| .|.| .
skgsrsygklvvelkeevelsdyvlrefkvtr.teeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdi
TINKCKTEGVIDVFQVLKSQRIQKPGSVQT
... | |...||||. | | |.. |||
llerikaealvDvfqtvkqlreqrnlmvqt
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 873-1095 | 8.9e-39 | 127.9 | In-house | 33-274 (296) | alignment | ||
Range on Protein: 873-1095
Range on HMM: 33-274/296.0
EVTHNIASQNNDRNRLNQFLPPDNYRVPLK---GE-HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQeVCYQYWS
. ... ..| ..|| . .|.|. || |. || . ||||||..... ||..|. | |. .| .||... |... |.|.|... . . . .||
dCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywp
NG---KLGEYNISLLNEEIHNAGY-----IERKIEVT---NDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRG-----NTSIVVHCS
| . || . ...|. . . .|| . . . .. ||..|.| |.. |. . |. . .. |. |.. . .||..|
nkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvss
DTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQ
| ..|| ...|. .... . |. .|||. .| |...|. |.
dGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLve
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 873-1094 | 6.3e-14 | 46.3 | In-house | 31-253 (307) | alignment | ||
Range on Protein: 873-1094
Range on HMM: 31-253/307.0
EVTHNIASQNNDRNRLNQFLPPDNYRVPLK---GEH-PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENdqEVCYQYWS
.|. ... | .. | .. | || |. | . |.| | ..| ||.|..|. || .||.|. .| |||| |. | | ||
slttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywp
NGKLGEYNI---SLLNEEIHNAGYIERKIEVTNDNKAGDK---QQVKQYQiTNWDSTGKMTNPQTILlvieemyRTQRKRgNTSIVVHCSDTVGRSAMFC
. . . || | .. . ||. . | . . .. .| ... .... | .| | |. . .||.. . | ..| .
kaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwq.gdvnnssdvysplrvl.......rklrnl.skpvvvqdilGvskaatlv
AAATTINKCKtEGVIDVFQVLKS---QRIQKPGSV
|. ... . | | . ||.. | ... ||
aieiallsll.rGpitkslvlravvflrlrrrlsv
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 874-1096 | 4.4e-49 | 162.7 | In-house | 3-231 (249) | alignment | ||
Range on Protein: 874-1096
Range on HMM: 3-231/249.0
VTHNIASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN
... . | |.|| .||.|. || |. .. ||||| .|.||. |..||.. |. .| .||.|. . ..|.||||... |...| |.|||..
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
G---KLGEYNISLLNEEIhNAGYIERKIEVTNDnKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAA
| . |.. . ||..|. ...|. |..|.|| . |.. .|...|.|.| .| .....| ||.. ... .. ..||||. |||...|.||
ggsleygdftvtllsvev.kddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaay
TTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. .. ..|. .|.....| | |.||.||.
lmleqlekelgvdleeavkllrsqRpgavqn
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 874-1096 | 5.8e-44 | 145.7 | In-house | 53-276 (319) | alignment | ||
Range on Protein: 874-1096
Range on HMM: 53-276/319.0
VTHNIASQNNDRNRLNQFLPPDNYRVPLK---G-EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCqenendQEVCYQYWSN
|. || |.||. . |. |. .| |. | | ||||| |..||. |. .| | |. || .||.|| . |...||.| .. | ||| .
qtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywpl
G---KLGEYNISLLNEEiHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAA
| ....... | | |. |.||...| | |.....|. . | |. | .. ... . |........|||||| |||. .. .
kivikeerfkvkvdsve.etaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivld
TTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. ... | | .||..... | |.. ||
vlldrmkeekqvdvynfvrdlrqqrntlvqd
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 874-1096 | 8.2e-44 | 145.2 | In-house | 17-240 (284) | alignment | ||
Range on Protein: 874-1096
Range on HMM: 17-240/284.0
VTHNIASQNNDRNRLNQFLPPDNYRVPLK---G-EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCqenendQEVCYQYWSN
|. || |.||. . |. |. .| |. | | ||||| ||.||. |. .| . |. || .||.|| . |...||.| .. | ||| .
qtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywpl
G---KLGEYNISLLNEEiHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAA
| ....... | . |. |.||...| | |.....|. . | |. | .. ... . |........|||||| |||. .. .
kivikeerfkvkvdsve.eseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivld
TTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. ... | | .||..... | |.. ||
vlldrmkeekqvdvynfvrdlrqqrntlvqd
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 874-1096 | 8.9e-41 | 134.8 | In-house | 43-270 (293) | alignment | ||
Range on Protein: 874-1096
Range on HMM: 43-270/293.0
VTHNIASQNNDRNRLNQFLPPDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN
|. . ...|...|| .. || |. || | . .. ||||| .|.||. .. || . |. .| .||.|. ......|||| | |. .. | .|| .
vkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPa
G----KLGEYNISLLNEEiHNAGYIERKIEVTNdnkAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQ-RKRGNTSIVVHCSDTVGRSAMFCAA
|. ...|..|| . .. |...... . ....|.||. | | | ...|.| .... ... .. .. |||||| |||. | |
deepvlyGdikvtlvaee.eledwvirelkiek...ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfial
ATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. ... ..| ..|.| .. . | .. |||
drllqaieeedyvdifgivaelReeRnllvqt
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 875-1096 | 9.1e-40 | 131.3 | In-house | 36-265 (288) | alignment | ||
Range on Protein: 875-1096
Range on HMM: 36-265/288.0
THNIASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEK-KAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN----
. || . ..|| . || |. || |.|.. ||||| |... ||.. .|. .|. ||.|. .. . |||| ...| ... . .|| .
siaiaklyseknrsrdilPyDhnRvklrgskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkge
-GKLGEYNISLLNEEiHNAGYIERKIEVTNDnKAGDKQQVKQYQITNWDSTGKMTNPQTILLVI---EEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAA
| |.....| ... . ..||..... .| ...|. |.|.| . | |.|.| .. |..|...... .| .||||| |||. .|.
tvkfgdlsvtlksvr.etethvervlkletl.dadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvy
TTINKCK-TEGVIDVFQVLKSQRIQKPGSVQT
. ... . .|..|. ||.. | |. .||.
aavrelekgnglldiiqvvsrlreqRrfmvqe
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 875-1096 | 2.9e-34 | 113.6 | In-house | 30-254 (273) | alignment | ||
Range on Protein: 875-1096
Range on HMM: 30-254/273.0
THNIASQNNDRNRLNQFLPPDNYRVPLKGEHPdYINAVFINGY--KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG--
. .|.|.|| . || |. ||.|..| . |||| .|. |.. .|.. |. .|...||.|. ..... |.|. .| |... | .|| .
evgkkkenkdknryrnvlPydetrvklgdegg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPeskn
-KLGEYN-ISLLNEEI-HNAGYIERKIEVtNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATT
|| .| . . .... . |. |...| .|...|. ..| . . ..| | .... .| .. |. | |. .. |||||| .||| .. . .
kklkvsnrlevellkvqkldgfvvralav.kdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvv
INKCKTEGVIDVFQVLKSQRIQKPGSVQT
.. . . .|| ..... | |. | |||
lglierdkefdvkeivrklreqrqgvvqt
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 875-1096 | 1.9e-29 | 97.4 | In-house | 47-277 (297) | alignment | ||
Range on Protein: 875-1096
Range on HMM: 47-277/297.0
THNI--ASQNNDRNRLNQFLPPDNYRVPLKGE----HPDYINAVFINGYKEK-KAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYW
|... | .| ..|| ...|| |. || || | . ||||| .| . |.| ...|. .| .||.|. .. |. ||.|.. .|.. . |..||
tkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckryw
SNG---KLGEYNISLLNEEIHNAGYIERKIEVTNDnKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGnTSIVVHCSDTVGRSAMFCAA
. . |.. |. | | |. | . . | .. . . | |. | ..| ......| . .. | | ..||||||| .||. ....
pdeGsevyhiyevhlvsehiwcddylvrsfylknl.qtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrs.cpivvhcsdGaGrtGvyili
ATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQT
.|. | ||. |. | |.|| |.|
dlvlnrllkGvkeidiaatlehlrdqrpglvkt
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 877-1096 | 2.7e-44 | 146.2 | In-house | 35-262 (290) | alignment | ||
Range on Protein: 877-1096
Range on HMM: 35-262/290.0
NIASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG--
...| .|| || |. || |. |. ||||| ||.| ..|...| | .|. .| .||.||.. ||. .||.|.| |... | .||..
gekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeege
---KLGEYNISLLNEEIHNAGYIERKIEVTNDnkaGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATT
. ||....| .|. . ... | ..|... .....|.|.. |.| | ......| .||.. ..|. . .. .||||| ||| .| .
eelefgefevtleeekavdddflirtLkveaq...kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyv
INKCKTEGV---IDVFQVLKSQRIQKPGSVQT
. |.| . .|||... . | |.. |||
rellkaekipeeldvfdlvlelrkqraalvqt
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 877-1096 | 5.2e-41 | 135.7 | In-house | 43-269 (297) | alignment | ||
Range on Protein: 877-1096
Range on HMM: 43-269/297.0
NIASQ---NNDRNRLNQFLPPDNYRVPLKG--EH--PDYINAVFINGYKEkkAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQeVCYQYWSN
. .. | ...| . || | || |. .. ||.|| |..|.|. .| . || .| .||.|. | .|..|||| ..||.|. | .|||.
qtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsd
GKLGEY-NISLLNEEIH-NAGYIERKIEVTNdNKAGDKQQVKQYQITNWDSTGKMT--NPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAA
.. ..|.. . .. |.|.|..|||. .|| .. ||||| ..| . . ...| .|.|. . .. .. ..|||. ||| .....
kgvttfGdvsvvllsvsereGfikrelevtk.gkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltid
TTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. . | | .|.|...| | ..| |||
svvaeakrekevdifglvkklrqerpylvqt
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 877-1097 | 5e-25 | 83.1 | In-house | 42-282 (300) | alignment | ||
Range on Protein: 877-1097
Range on HMM: 42-282/300.0
N--IASQNNDRNRLNQFLPPDNYRVPL---KGEHPDYINAVFING--YKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN
. .|...|| ...|| .. || | | .. .|||| |. ... .|.| .|. .| ..||.|. . .|. |||| .|.|. .| ...|. .
staklpenaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPk
G-------KLGEYNISLLNEEiHNAGYIERKIEVTNdNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNT--------SIVVHCSDT
. |..... | . .| ..... ......| | |.| | .... | .||. .|| .. ..||||.
leskkktvefgkfkvttkfse.dsdsvittglklkh.lpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaG
VGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
|||. . . |. ... .||. .||. | |. |||.
vGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtl
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 878-1097 | 1.8e-38 | 127.5 | In-house | 44-274 (325) | alignment | ||
Range on Protein: 878-1097
Range on HMM: 44-274/325.0
IASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNvTAIVMLCQENENDQEVCYQYWSNG---
.| ..||.. .. |. || |. . ||||| ... .|.|. |. | .|. .| ..|... | . ...|.. | ..... | .|| .
mkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.csvvvvlneldlgkdrcavywpkemgk
--KLGEYNISLLNEEIHnAGYIERKIEVTNdNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVI---EEMYRTQR--KRGNTSIVVHCSDTVGRSAMFCA
..| ...| | . |. |...| . | |. . |||.|. || | | |.. .. ... . . .. | |.||||. |||. .| .
sktfGglevklrtieei.sdyvhrvldvkq.vkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfis
AATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTV
. ..| .| .|.|...| | ..| |.||
lysalakvieesrvdifgfvkklrkdrpsmvetv
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 878-1096 | 1.1e-35 | 117.9 | In-house | 37-260 (280) | alignment | ||
Range on Protein: 878-1096
Range on HMM: 37-260/280.0
IASQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFIN----GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN----
..| ..|| || |. || || .. ||||| ..| . . . .|.. |. .|| .||.|. ..... |||| . |. . |.||| .
rkpenlsknryrdilpydatrvklkesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetede
GKLGEYNISLLNEeIHNAGYIERKIEVTNDNKaGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN
..||... . .| .. |. |.. ... .. ..... | | ..| | .... .| ..|.. |..|. .. .||||| .||. .. . |..
leygefsvkceke.detksyvlrelvlkdket.keerkilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletala
KCKTEGVIDVFQVLKSQRIQKPGSVQT
. .. . . .... | |. |||
lieaaepvypldivrtmrdqramlvqt
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 878-1096 | 5.4e-34 | 112.4 | In-house | 16-249 (270) | alignment | ||
Range on Protein: 878-1096
Range on HMM: 16-249/270.0
IASQNNDRNRLNQFLPPDNYRVPLKGEHPD----YINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG--
| ... || .. || . || |. .. | |||| ...|... ||..| | .|. .| ..||.|| ...||||||. . .|. .. | .||..
eaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepk
---KLGEYNISLLNEE-IHNAGYIERKIEVTndnKAGDKQQVKQYQITNWDSTGK------MTNPQTILLVIEEMYRTQRKRGN-TSIVVHCSDTVGRSA
|| . .|. |... .. ||| ...... . |..... .. ..| | .... .| ..... |.... . . ..||||. |||.
ekvkledgkikvlalseekeegyiltrlrle...ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtG
MFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.. | .... .... .|| .... | ... ||.
tlialDiavrlLeetkkvdvlaiieelRkdRmalvqh
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 878-1095 | 8e-25 | 82.1 | In-house | 50-267 (290) | alignment | ||
Range on Protein: 878-1095
Range on HMM: 50-267/290.0
IASQNN--DRNRLNQFLPPDNYRVPLK-GEHPDYINAVFINGYKekKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG--K-
| .| .|| . | || || | . ||. | ...| | ||... .. .|. ..|.|. . .|.||||||. |. . | ||. . .
ifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGev
--LGEYNISLLNEEIHNAGYIERKIEVTnDNKAGDKQQVKQYQITNWDSTGkMTNPQtiLLVIeEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTIn
.||. . .|. ..| | . . | | ..| . ..| ..| | ... . | .. . |. || . .||||| .||. | | ...
ltfGeitvlcseeddkdaniikktlsvr.dkdsGkehklkhlkikswpdks.valst..lall.rtlrilrka.sGpvvvhcsaGiGrtGtfvaievgl.
KCKTEG-VIDVFQVLKSQRIQKPGSVQ
.. ..| .|. .. .. | . .|||
qilldGkeldlldlvralrnsrlnsvq
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 878-1095 | 2e-22 | 74.3 | In-house | 42-263 (439) | alignment | ||
Range on Protein: 878-1095
Range on HMM: 42-263/439.0
IASQ--NNDRNRLNQFLPPDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENEndqevCYQYWSNGK
.|.| .. .|| .. . | || | | |||| .|.|| ..| .| .. | .|. .||... ..... ||||.. | |.|| .
laaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlve.....sykywpsda
LGEY-NIS-LLNEEIHNAGYIERKIEVTNDNKAGDKQ-QVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTI
| .|. . .| |. | . | |. ..|. | |.. . | .. .| . . .. |. .||||| |||. | ..
evcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdial
NKCKTEGVIDVFQVLKSQRIQKPGSVQ
.. |.| .|. ..| | |. ||
eqlklenkvdikgivkvlrkqrkqmvq
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 879-1096 | 2.9e-49 | 163.1 | In-house | 6-228 (245) | alignment | ||
Range on Protein: 879-1096
Range on HMM: 6-228/245.0
ASQNNDRNRLNQFLPPDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG---K
| |.|| ..|| |. || |. . ||||| ...||. .. ||.. |. .| .||.|. . ..|.||||..| |.... |.|||..| .
lpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgeslt
LGEYNISLLNEEIhNAGYIERKIEVTNdNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKC
|.. . ||.||. ...|. |..|||| .. . ...| .|. ..|. | ......| ..|.. . ... .|. ..||||. |||...|.|| . ..
ygdftvtllseeh.lddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleql
KTEGVIDVFQVLKSQRIQKPGSVQT
..|. .......| | |.||.|||
ekelgvsleeavkelrsqRpgavqt
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 879-1095 | 1.9e-47 | 156.9 | In-house | 45-270 (307) | alignment | ||
Range on Protein: 879-1095
Range on HMM: 45-270/307.0
ASQNNDRNRLNQFLPPDNYRVPLK----GEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS---NGK
|. .|| .. . |..|| || |. ||||| ||.|||||| ||.| |. .|. .||.|| . .|| |||| ...| ... | .||. . .
kkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevq
LGEYNISLLNEEIHNaGYIERKIEVTNDNKAG----DKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATT
|. .. | .|| |. ||.|...|.. .. . |...| ||. |.|. . ....| .||... ... .. |||||| ||||..| | .
ygdilvklvseekhs.dyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsl
INKCKTEGVIDVFQVLKSQRIQKPGSVQ
....|.| .|.|.. | | |.. ||
lqqlkaedkvdifetvkdLrsqRnllvq
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 879-1096 | 1.8e-44 | 147.5 | In-house | 7-227 (243) | alignment | ||
Range on Protein: 879-1096
Range on HMM: 7-227/243.0
ASQNNDRNRLNQFLPPDNYRVPLKGehPDYINAVFINGYKeKkaFIIAESPMFNTARN----FWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKLGE
.| ..|| .|| |. || |.| ||||| .|.... . .|. |. .| . ||.|. . ..|.||||... |...| |.|||.... .
lpenlsknrysdilpydhsrvkleg..sdyinanliyvtp.r..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtyg
YNISLLNEEIHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRK-------RGNTSIVVHCSDTVGRSAMFCAAATT
. | .| | ..|. |.....| . . ...| .|. ..| | ..|. .| ..|.. ... .. ..|||| |||.....|| .
dftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylm
INKCkteGvIDVFQVLKSQRIQKPG-SVQT
. .. | .|.....| | |.|| .|||
llll...g.vdleeavkllreqRpgkavqt
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 879-1096 | 4.2e-41 | 135.8 | In-house | 41-262 (315) | alignment | ||
Range on Protein: 879-1096
Range on HMM: 41-262/315.0
ASQNNDRNRLNQFLPPDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN-----
..| .|| . || |. || | . . ||||| .|..... ||.| . | . .||.|. . .||.|||. . .|.|. | ||| .
etinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkads
GKLGEYNISLLNEEIhNAGYIERKIeVTNdnKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTIN
..|.....||. | ... . ||. || |. ....| |.| |.| | . ..| .| |. ... . |..|||| |||. ..... ..
vefGsikvellslea.dtdgvarkl.vtr..kseesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevva
KCKTEGVIDVFQVLKSQRIQKPGSVQT
. | . ..|||...| | ..| |||
qikrtrsvdvfnfvknlrakrpylvqt
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 879-1097 | 5.1e-40 | 132.4 | In-house | 38-262 (281) | alignment | ||
Range on Protein: 879-1097
Range on HMM: 38-262/281.0
ASQNNDRNRLNQFLPPDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGK---
| .| .|| . |. || . . .. ||||| |..|||..|..|....|. .. .||.|. ...|.||||. .| |... |..|| ...
adenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnsel
-LGEYNISLLNEEiHNAGYIERKIEVtnDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINK
.|.. .. ..|| ..| |||||... ... |....|.| . |.| .| .... .| .|......|. ....|.||| |||. . | . ...
kygdvtvkstaee.ekatyierkfkl..eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvka
CKTE-GVIDVFQVLKSQRIQKPGSVQTV
...| .|| .|... | .. ||||
veaeleeldvkavvaelrkernlmvqtv
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 879-1096 | 8.4e-35 | 115.2 | In-house | 39-275 (297) | alignment | ||
Range on Protein: 879-1096
Range on HMM: 39-275/297.0
ASQNNDRNRLNQFLPPDNYRVPLKG----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS-----N
| .|| . | |. || |. |. ||||| |..|||.||||| . |. .| ..||.|. ...| ||| . |. . | |||
lranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeess
GKLGEYNISLLNEEIHNAgYIERKIEVTNdNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQR---------KRG---NTSIVVHCSDTVGR
. |....| .. | ... | .|..|..| | .....| .|.. | | . ...| |.|.. ..| ..| . |||||| .||
aefgdlsvsnveveeeed.ykvrvleikn.vkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGr
SAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. |.. .... ...|..||....| | |. |.||
tGtfitldiclsrleevgtvdvvetvkllrtqrafsiqt
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 879-1096 | 4.7e-27 | 89.4 | In-house | 42-221 (392) | alignment | ||
Range on Protein: 879-1096
Range on HMM: 42-221/392.0
ASQNNDRNRLNQFLPPDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDqevcyqywsngklge
| .|| .. || |. || | . ||.|| .|.... .||.| ...| . .||.|. . |||.|.|. . .| |
keinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd...............
ynisllneeihnagyierkievtndnKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMyrtQRKRGNTS--IVVHCSDTVGRSAMFCAAATTINKCK
| |.. | |...|.| . ..| .|.|. . . |. . ...||| |||... . . . ..|
..........................kgddartvaqfhftewPdkdvpkhtssllkfikev...kadfGqythpliihcsagvgrtgvvisidsvvahak
TEGVIDVFQVLKSQRIQKPGSVQT
. ..|||... | ..| |||
ktrmvdvfnfvtnirrkrpymvqt
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 879-959 | 6.4e-08 | 26.4 | In-house | 31-114 (332) | alignment | ||
Range on Protein: 879-959
Range on HMM: 31-114/332.0
ASQNNDRNRLNQFLPPDNYRVPLKGE--HPDYINAVFINGYKEKKAFIIAESPMFN-TARNFWKMIDDRNVTAIVMLCQENEND
.| | ||. .. | || | . . |. || ...|| .| |.|.|..|. . | ||.|. .|. . |... . .|..
flnnmdmnriphlycfdhsrvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekq
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 880-1096 | 8.3e-51 | 167.6 | In-house | 7-227 (250) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 7-227/250.0
SQNNDRNRLNQFLPPDNYRVPLKGEH----PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEvCYQYWS---NGKL
||...|| .... |. || |. |. |||||.|..||.|.||||.. .|. .| .||.|. ......|||| . .|.... . ||| |
pqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaeky
GEYNISLLNEEIHnAGYIERKIEVTNDNKAgDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK
|. .|||..|.. | |. ||. ... .|| |...|.|.. ..| | . ...| ..... ..|.. ||. ..|.|| |||| |.| . ... |
Gdvtvsllskeef.adytkrklklskakka.derivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlk
TEGVIDVFQVLKSQRIQKPGSVQT
.| |.|||.|.| |...|..|..
kekvvdvfkvikvlrkdrphaves
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 880-1096 | 4.7e-48 | 158.8 | In-house | 56-280 (330) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 56-280/330.0
SQNNDRNRLNQFLPPDNYRVPLK---G-EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN-GKL--
.|...||. . || | || | | |. ||||| ||.|||||. || | | .| .||.|| ... ..|||| . .| ..| |.||| . | .
eenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvty
GEYNISLLNEEiHNAGYIERKIEVTNDNK---AGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNtSIVVHCSDTVGRSAMFCAAATTIN
|. .... .|. | ||. |.. .. ....|.|. | | | ..|. .| ..... ..... .. .|||||| |||. |.. . ..
Gnirvevedet.vlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavle
KCKTEGVIDVFQVLKSQRIQKPGSVQT
. |.|...|||...|. | |.| |||
rvkaerkvdvfefvkrlrlqrpqmvqt
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 880-1096 | 3.3e-43 | 142.7 | In-house | 41-262 (314) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 41-262/314.0
SQNNDRNRLNQFLPPDNYRVPL---KGE-HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG--KLG
.|...|| .. |..|. || | .|. . ||||| .|..|| .|||.. |. .| ..||... | | ..|||| . |. . |..|| . . |
denreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtevyg
EYNISLLNEEIhNAGYIERKIEVTN-DNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCK
. .. |.. |. .| .. | |.. . ....|.|.| ..| . . .. ...| .. .. .| . .. |||||| ||. .|.| .. .. .
dikvelvetel.laelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmie
TEGVIDVFQVLKSQRIQKPGSVQT
.|||.|||.. |. | .|. |.|
regvvdvfnavktlrsrkvnmvet
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 880-1096 | 4.4e-38 | 126.0 | In-house | 47-264 (315) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 47-264/315.0
SQNNDRNRLNQFLPPDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKL--G
..| ..|| . .. |. || | . .| ||.|| ||.||. |. .| |..| .. ..||... . ... |||| . |.... . .|| . |. |
ienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdkkviyG
EYNISLLNEEiHNAGYIERKIEVTNDNKAgdkQQVKQYQITNWDsTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
.. ... .|| .| | | . |. ... ..| |...| | . .... . |. . . .. ..||||||. |||. |.. . ... ..
kitvtrksee.vnteytvrtlsvvfgdni...revvqlhytswp.dmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaea
EGVIDVFQVLKSQRIQKPGSVQT
| .|||..... | .. . ||.
enaidvynfitgvrqnrikmvqv
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 880-1096 | 1e-36 | 121.5 | In-house | 26-253 (274) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 26-253/274.0
SQNNDRNRLNQFLPPDNYRVPLKGE-----HPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKL-
. .. .|| .. || .| || |. | .|||| .| ||.| .||.. . |. || .||.|| ..|. |||| . .|.... | .|. . .
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
---GEY-NISLLNEE-IHNAGYIERKIEVTNDNKagdKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNT--SIVVHCSDTVGRSAMFCAAA
..| .... .|. ... .| ||. . . .. ...|| | |.| . ...|.| ...|. ...... . ..||||| .|| .| |.
eiserygdveikvekiverndysvrklvlkyler...ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiais
TTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.... . |.|.||... |... | |||
iavrqlreeivvdvlkivcnlrldrGGmvqt
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 880-1096 | 8.7e-36 | 118.4 | In-house | 52-282 (306) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 52-282/306.0
SQNNDRNRLNQFLPPDNYRVPLK---GEHPDYINAVFINGY--KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN----G
.|. .|| . || |. || || ||||| .|.. ...|..| .. . .| .||.|. . | . |||. .|.| .| |..|| .
penkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeeke
KLGEYNISLLNEeIHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRG---NTSIVVHCSDTVGRSAMFCAAATT
. |..... ..| ..| || |.. |.. .|......| ||. ..| | ..|...| .|.. | |.. . .||||||. .|| | .
eyGkisvtnvse.ksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDil
INKCKTEGV---IDVFQVLKSQRIQKPGSVQT
... ...|. ||. .. || | |. | |||
lkliekkgldadidiqklvksvreqrsglvqt
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 880-1096 | 1.8e-18 | 61.2 | In-house | 35-254 (281) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 35-254/281.0
SQNNDRNRLNQFLPPDNYRVPLKG-----EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKLGE
|| .|| . | || || . ||| | .| |. .|... | .| .||.|| . | |||||||| | ..| | .|.
pvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcc
YNISLLNEEIHNAgYIERKIEVTND--NKAGDKQQVKQYQITNWDSTgKMTNPQTILLvieEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCK
.. | . .. ... . | |. . . .. .| .. . ..| .. | | | | |.||| |||| . | ... .
lqfdklsvsyeds.tvnkslvttrlnlsyegetrlithwlwkewpdw.qvpessevml...kilrkirar.stppvihcsagvgrsgtlmaveialqsih
TEG-VIDVFQVLKSQRIQ-KPGSVQT
. . |. |.. |. . ||||
shftlpdikqivshlrvtgraasvqt
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 880-1096 | 3e-16 | 54.0 | In-house | 46-272 (305) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 46-272/305.0
SQNNDRNRLNQFLPPDNYRVPLKGEHP-DYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKLG-----
.|....|| . || || |.| | .|| | .. . | || ...|. .| .|| | . .| || |||. | . |..|.. .
aqeagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefe
--EYNISLLNEEIHNAGYIE------RKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTIllvIEEMYRTQRKRGntSIVVHCSDTVGRSAMFCAAA
. ||. | .. . . .. ... . .....|..| .| | . ..| .| . ... .| |||||| .||.
ekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlai...lellekarpskg..pivvhcsagigrtgsvvmle
TTINKCKTEGVID-VFQVLKSQRIQKPGSVQT
... . .|. ..|. | |. |.||
yildqllagqiiedtdkilqkireqrnnsiqt
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 880-1096 | 3.4e-12 | 40.4 | In-house | 49-270 (302) | alignment | ||
Range on Protein: 880-1096
Range on HMM: 49-270/302.0
SQNNDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTA---RNFWKMIDDRNVTAIVMLCQENENDQeVCYQYWS--NGKLGE
.| ..|. ... .|. .| |..| .|.|| .. . .. |.| | ... .||.|. ..... .|.| .|.| .. ... |. |
kknlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgdyke
YNISLLNEE----IHNAGyIERKIEVTNDNKAgDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTINK
|. .| ... . ||| .. . . .. | .||| .. .. .. ..... .. ..|. .|| ..| ..|....|
ygkmfvNnrkVekaeeek.tryviEvlPegcs.nsvlanvyvltnWkqkkvpvkyaeliktaakvfak.kikadentvivSknGaGRagafltlavavek
CKTEGVIDVFQVLKSQRIQKPGSVQT
... . ...|| | |.| .|..
lqkgkepnikeivksiRsqRpravds
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 880-927 | 8.3e-06 | 19.9 | In-house | 46-94 (95) | alignment | ||
Range on Protein: 880-927
Range on HMM: 46-94/95.0
SQNNDRNRLNQFLPPDNYRVPLKGE-HPDYINAVFINGYKEKKAFIIAE
| .||. . .| | || | |||||.|..|| |...| |.
eanipknrflnifpydatrvvlttkrdsdyinacfvdgyarkncyiaaq
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 881-1096 | 2.8e-40 | 132.9 | In-house | 42-261 (515) | alignment | ||
Range on Protein: 881-1096
Range on HMM: 42-261/515.0
QNNDRNRLNQFLPPDNYRVPL----KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN-----GK
| .|| . || |. || | | ||.|| .|.... ||.| . | . .||... . |||.|.|. . .|.|. | .|| . |
infkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvk
LGEYNISLLNEEIhNAGYIERKIEVTNDNKagdKQQVKQYQITNWDSTGKMTNPQTILLVIEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKC
.|.....|. | .| | ||..|. ... . | |.. |.| | . ...| .| |. .... . . ....||| ||| ..... . .
fGsikvelvslea.ctggikrkltvlkgdd...srtvtqfhfteWPdkGvpkhtssllklikev.kadhgqythpliihcsaGvGrtGvvisidsvvaha
KTEGVIDVFQVLKSQRIQKPGSVQT
|| ..|||.... | ..| |||
kttrmvdvfnfvtnirqkrpylvqt
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 881-1097 | 1.8e-33 | 110.6 | In-house | 37-263 (287) | alignment | ||
Range on Protein: 881-1097
Range on HMM: 37-263/287.0
QNNDRNRLNQFLPPDNYRVPL--KGEH-PDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG----KLG
. .|| . || |. || | .||. ||||| .. .|....||| | .|. | |.||... .......... .| |. . ||.|| . ..|
aavkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvG
EYNISLLNEEIHNAGYIERKIEVTNdNKAGDKQQVKQYQITNWdsTGKMTNPQ---TILLVIE--EMYRTQRK-RGNTSIVVHCSDTVGRSAMFCAAATT
| . ||. .| . | | . . . .. . . |||... .| | | | .|.. . .|. . .|||.. .||| .. | .
GysvvlldydikePeygvralrlid.letrearvvkqldllsw..PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvl
INKCKTEGVIDVFQVLKSQRIQKPGSVQTV
... . | .|| .|. | .. . ||.|
vsrledlGrvdvaavvirlreyraalvqav
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 881-1096 | 3.8e-26 | 86.8 | In-house | 2-224 (237) | alignment | ||
Range on Protein: 881-1096
Range on HMM: 2-224/237.0
QNNDRNRLNQFLPPDNYRVPLKGE--HPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG----KLG
.|. .|| . | || ||| ||||| ...|. | .| |. |. .. .||.|. . . . |||| |.... |..|| . |
enkiknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaayg
EYNISLLNEEIHnAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRK-RGNTSIVVHCSDTVGRSAMFCAAATTINKCK
. .|| .| . | | . ... . . . ..|||.| | | . ..| .. .. . ..||| |||...| . . ..|
vltvslkkkeef.sdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
TEGVIDVFQVLKSQRIQKPGSVQT
. |.|... ..| ..| .||
ekkvvdiynyvysieedrpyiiqt
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 881-1088 | 5.7e-22 | 74.3 | In-house | 45-255 (314) | alignment | ||
Range on Protein: 881-1088
Range on HMM: 45-255/314.0
QNNDRNRLNQFLPPDnYRVPLKG---EHPDYINAVFINGYkekKAFIIAESPMFNTARNF----------WKMI--DDRNVTAIVM--------------
| |.|| ..|| | || |.| . ||||| ...|. ..||... |. .| .| |.|. .|.|| |||
lnrdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLd
-------LCQENENDqevcyqywsnGKLGEYNISLLNeeihnagyierkiEVTNDNKAGdKQQVKQYQITNWDStGKMTNPQTILLVIEEMYRTqrkRGN
|.. .| . . . .. ||. |...|.. .... .| .... | .. .. ..| . . . .
aAlgKtpllildgng..........neptaadlellk.............eelydpelf.erlgikylripvpD.gsaplledfdeflefieea...dkg
TSIVVHCSDTVGRSAMFCAAATTINKCKTeGVIDVFQVLKSQRI
. ..|||.. .||.. |..|| . ... . .... ....|
gpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRp
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 881-971 | 2.9e-14 | 47.6 | In-house | 30-126 (297) | alignment | ||
Range on Protein: 881-971
Range on HMM: 30-126/297.0
QN--NDRNRLNQFLPPDNYRVPLKGEHP--DYINAVFINGYKEKK--AFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGK
.| .|| .. | |. || |.. . ||||| .. .|.. .|.|. |. .| .||... ...| .|||... .|. .. |. || . .
rnsslrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvv
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 881-1020 | 1.9e-07 | 24.8 | In-house | 51-193 (332) | alignment | ||
Range on Protein: 881-1020
Range on HMM: 51-193/332.0
QNNDRNrLNQFLPPDNYRVPLKGE---HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGK-----L
.. .|| . . .| | | | | . |||| .. . . .|.. . . ||.|. ... |||.| .. |.. | .|. .
eavnrn.vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkf
GEYNISLLNEeIHNAGYIERKIEVTNDNKAgdkQQVKQYQITNWDSTG
| ... . .... . |..|.. |.. .|. |.. | |
Gildverkef.vkrniletrllelskGnet...hrvlhykvfGwtett
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 882-1096 | 7.6e-57 | 187.8 | Pfam-A | 1-222 (235) | alignment | ||
Range on Protein: 882-1096
Range on HMM: 1-222/235.0
NNDRNRLNQFLPPDNYRVPL--KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS-----NGKLGE
| ..|| ...|| |. || | .... ||||| ...||||||.||... |. .| ||.|. ...|..||||....|...| | |||. . |.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
YNISLL-NEEIHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
... | .|. ....|. ||.|...... .|..|||...||| | ..|. .| .|... ... . ....|||||. |||...|.|. . ......
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqlea
EGVIDVFQVLKSQRIQKPGSVQT
|. .||.|..|. | |.||.||.
eeevdvlqivkelRkqRpgmvqs
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 882-1096 | 7.6e-57 | 187.8 | In-house | 1-222 (235) | alignment | ||
Range on Protein: 882-1096
Range on HMM: 1-222/235.0
NNDRNRLNQFLPPDNYRVPL--KGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS-----NGKLGE
| ..|| ...|| |. || | .... ||||| ...||||||.||... |. .| ||.|. ...|..||||....|...| | |||. . |.
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygd
YNISLL-NEEIHNAGYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKT
... | .|. ....|. ||.|...... .|..|||...||| | ..|. .| .|... ... . ....|||||. |||...|.|. . ......
ikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqlea
EGVIDVFQVLKSQRIQKPGSVQT
|. .||.|..|. | |.||.||.
eeevdvlqivkelRkqRpgmvqs
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 882-1096 | 1.6e-28 | 94.9 | In-house | 1-156 (182) | alignment | ||
Range on Protein: 882-1096
Range on HMM: 1-156/182.0
NNDRNRLNQFLPPDNYRvplkgeHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCqenendqevCYQYWSNGKlgeynislln
| |.|| .||.|. | ..||||| .. |. . ||.. |. .| .|..|. ....|.||.|. ...|| .
nldknrysdilpydhsr......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpell..........
eeihnagyierkievtndnkagdKQQVKQYQITNWDSTGKMTnPQTILLVIEEMYRtqrkrGNTSIVVHCSDTVGRSAMFCAAATTINKckteGvIDVFQ
.... ||. ..|. | . ....| |||... . ..|||| |||.....|| . . | .....
.......................erlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vslee
VLKSQRIQKPGSVQT
..| | ..||.|.|
avklvrsrRpgmvit
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 882-1095 | 9.3e-17 | 55.6 | In-house | 55-273 (305) | alignment | ||
Range on Protein: 882-1095
Range on HMM: 55-273/305.0
NNDRNRLNQFLPPDNYRVPLKGEHP-DYINAVFING-YKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN--GKLGEYNI
. .|| .. |. | |. | ||| | .. .| || |. |. .| .|| |. ...| |||||. | . | ||| |. | .
aitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelks
SLLNEEIHNAGYIERKIE--VTNDNK---AGDKQQVKQYQITNWDSTGKmtnPQTILLVIEEMyRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCK
.. |.. . .|| | .| | ..| |.. | |.| | | | .| . . | . |||||| .||. | ..|
givvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgv...ppckltslell.sair.gskvpivvhcsagigrtgtivaieyilekia
TE-GVIDVFQVLKSQRIQKPGSVQ
. . . ...|. | |. |.|
enkpcppmpelvkalrdqrafsiq
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 883-1089 | 5.4e-13 | 43.3 | In-house | 44-257 (312) | alignment | ||
Range on Protein: 883-1089
Range on HMM: 44-257/312.0
NDRNRLNQFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG----KLGEYNIS
.| || . | | | |. || | |.. . |.....|. ||. .||.. |.|..|| |. | | .| |. .| .. .
kdlnrypniqcwdrgrftlagdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvy
-LLNEEIHNAGYIERKIEV----TNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAAA---TTINK
|| | || . .|.. ....|| . | | .| | .. . |. . .. ||| |||. .. ... .
teycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsav.....kkdkkpviahcsagvgrtgtlaliesmiaalrh
CKTEGVIDVFQVLKSQRIQ
. . | |.| .|. .| .
prkqnvkdsfvllrkdrar
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 883-955 | 1.1e-07 | 25.7 | In-house | 49-119 (347) | alignment | ||
Range on Protein: 883-955
Range on HMM: 49-119/347.0
NDRNRLnqFLPPDNYRVPLKGEHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQE
.| |. | |.. . . |||| |. . .| .|... |. .| |.||||. .|| .| . .
idatrv..vlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifep
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 884-1096 | 4.2e-23 | 76.7 | In-house | 10-226 (239) | alignment | ||
Range on Protein: 884-1096
Range on HMM: 10-226/239.0
DRNRLNQFLPPDNYRVPLK----GEHPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS--NGKLGEYN
.|| . . | || |. | ||||| .. | ||.| .. . .. .||.|. . |||| | .. |.||| | .
aknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycnlr
ISLLNEEIHnAGYIERKIEVTNDnKAGDKQQVKQYQITNWDSTGKMTNpQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV
..| . |. | || | . ... ... | ||..| | | | .| . . | |.||| |||. | . . ..| .
vtlrktevf.adyiirtfvmsqv.gqteeryvyqyhftvwpdkgvpqy.atavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqkt
IDVFQVLKSQRIQKPGSVQT
.|.|. .|. | ..| |||
vdifnyvkairedrphmvqt
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 884-1096 | 4.2e-23 | 76.7 | In-house | 9-225 (239) | alignment | ||
Range on Protein: 884-1096
Range on HMM: 9-225/239.0
DRNRLNQFLPPDNYRVPLK----GEHPDYINAVFINGYKE-KKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWS--NGKLGEYN
.|| . . | || |. | ||||| .. | ||.| .. . .. .||.|. . |||| | .. |.||| | .
aknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycnlr
ISLLNEEIHnAGYIERKIEVTNDnKAGDKQQVKQYQITNWDSTGKMTNpQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV
..| . |. | || | . ... ... | ||..| | | | .| . . | |.||| |||. | . . ..| .
vtlrktevf.adyiirtfvmsqv.gqteeryvyqyhftvwpdkgvpqy.atavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqkt
IDVFQVLKSQRIQKPGSVQT
.|.|. .|. | ..| |||
vdifnyvkairedrphmvqt
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 898-1096 | 2.9e-24 | 81.2 | In-house | 4-158 (176) | alignment | ||
Range on Protein: 898-1096
Range on HMM: 4-158/176.0
RVPLKGEHPDYINAVFINGYKekkaFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNgkLGEYNIsllneeihnagyierkievt
|.. ....||||| .| |.. .|. |. .| .|..|. . ..||.|.|..| | .. |..||. | ...|
rllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi....................
ndnkagdkqqvkQYQITNWDSTGKMTNpQTILLVIEEMYRTQRKrGnTSIVVHCSDTVGRSAMFCAAAttinKCKTEGVIDVFQVLKSQRIQKP-GSVQT
||. ..|. | . . .| ..|.... ... | ..|||| .||.....|| ...| ..|...|. | |.| |.|||
............qylhlpwpDhgvpdl.elllellefirealke.g.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqt
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 902-1003 | 2.3e-10 | 34.3 | In-house | 86-189 (349) | alignment | ||
Range on Protein: 902-1003
Range on HMM: 86-189/349.0
KGEHPDYINAVFIN--GYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKLGEYNISLLNEEIHNAGYIERKIEVTND
| ||||| ... .. .| .| |. | .|.|.| .| .. | ...|.. | |..|| ... .... | | . |. .| ..
sgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqelsysnitvklqnsslyianvqGnslrvstv
NKAG
...
kdtd
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 904-1096 | 5.6e-25 | 83.5 | In-house | 3-146 (172) | alignment | ||
Range on Protein: 904-1096
Range on HMM: 3-146/172.0
EHPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQEnendqevcyqywsngklgeynisllneeihnagyierkievtNDNKAG
|. ||||| ....| . ||. |. || ||.|. ....|.||.|... .. .
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..........................................lydpel
DKQQVKQYQITNWDSTGKMtNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTInkcktEGViDVFQVLKSQRIQKPGSVQT
.... ||. ..|. | ... .| ..| ... . .. . ..|||| |||.....|| . .|. ....... | ..||.||.
lerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.....lgl.sleeavalvrekRpgavqn
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 904-1093 | 2.7e-18 | 61.7 | In-house | 16-153 (178) | alignment | ||
Range on Protein: 904-1093
Range on HMM: 16-153/178.0
EHPDYINAVFINGYkekkaFIIAESPMfntaRNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKLgeynisllneeihnagyierkievtndnkag
| |||||..| .. .... |. ...... . ..|.||.|..| |. .. |..|| .
ersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag...............................
dkqqvKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKckteGViDVFQVLKSQRIQKPgS
||. .... | . .. .| ..| . . . . . ..|||| ||||....|| . |. ....... | ..|
.....iqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.i
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 905-1096 | 1.1e-27 | 92.8 | In-house | 3-210 (272) | alignment | ||
Range on Protein: 905-1096
Range on HMM: 3-210/272.0
HPDYINAVFINGYKE---KKAFIIAESPMFNTARNFWKMiDDRNVTAIVMLCQENENDQEVCYQYWSNGKLGEYNISLLNE--------------EIHNA
..|||| ...|| ..... . |. .||..||.. . ....||.|..|.| ... |..|| . .. ..| . |..
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
GYIERKIEVTNDNKAGDKQQVKQYQITNWDSTGKMTNPqtILLVIEEMYRtqrkrgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVID--------V
|| |....|. .||. .| ... |.| | ... .| ..|.. . . ..|||| ..|.....|. . | ..| .
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FQVLKSQRIQKPGSVQT
..... | | ||.|||
eeaveelraqrpgavqt
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 905-1096 | 1e-19 | 66.1 | In-house | 2-138 (151) | alignment | ||
Range on Protein: 905-1096
Range on HMM: 2-138/151.0
HPDYINAVFINGYkekkaFIIAESPmfntARNFWKMIDDRNVTAIVMLCQENENDqeVCYQYWSN-Gklgeynisllneeihnagyierkievtndnkag
..||||. .. |. ... | |.... . ....||.|..| |.. |..|. . |
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
dkQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRtqrkRGNTSIVVHCSDTVGRSAMFCAAATTINKcktegvIDVFQVLKSQRIQKPGSVQT
.|....|..|. .| ......| ..|.. . .| ..|||| .||.....|. . . ......|. |.. ||.||.
..ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqp
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 905-1024 | 1.1e-10 | 35.9 | In-house | 12-129 (130) | alignment | ||
Range on Protein: 905-1024
Range on HMM: 12-129/130.0
HPDYINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQevcyqYWSNGK-LG--EYNISLLNEEIHNAGYIERK-IEVtNDN
.|||| |. . .. .. |. .|. .||||. .| | .|.| .|.|. || . . | | .| . . .. .|. . .|. ...
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeede.....ywpdsePlewyeediivtltdrdefknikasnlei.esd
KAGDKQQVKQYQITNWDSTGKMTN
.| . .||.|| | | |
lneshqaltmfqisnwpsdgttpn
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 906-1087 | 2.5e-15 | 51.4 | In-house | 46-235 (290) | alignment | ||
Range on Protein: 906-1087
Range on HMM: 46-235/290.0
PDYINAVFINgYKEKKAFIIAESPMFNT-------ARNFWKMIDDRNVTAIVMLCQENENDQE----VCYQYWSN--G---KLGEYNISLlNEEIHNAGY
||| | .. . . ..|. .|| .. .|| |. . .|. .||||. .|.... | .| . | |.. ... . ... .
ddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkC.kskekeddv
IERKIEVTNDNKagDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQR
..|...|. |.. . .|. ... .|... ...|.| .|. . | .| ..||| | . |||.. | | |.| . . .|||. |
etRelvvkfdde..eeftvtHsllkgWnklnvqedtktllsliqkv.....kasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalr
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 907-1096 | 1.4e-30 | 101.6 | In-house | 3-155 (174) | alignment | ||
Range on Protein: 907-1096
Range on HMM: 3-155/174.0
DYINAVFINGYKEKKAFIIAESPMFntarnFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNgklgeynisllneeihnagyierkievtndNKAGDKQ
||||| ..... . .|. |. ||.|. . ..|..|||..|.|.. . |..||. .. ..
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredler
QVKQYQITNWDSTGKMTNPQtILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKtEGVIDVFQVLKSQRIQKPGSVQT
. ||. ..|. | . .. .| ....... . . .. ..|||| |||.....|| . . |...|........| |.||.|||
lgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqt
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 908-1096 | 1.8e-24 | 81.0 | In-house | 77-266 (301) | alignment | ||
Range on Protein: 908-1096
Range on HMM: 77-266/301.0
YINAVFINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSN-----GKLGEYNISLLNE-EIHNAGYIERKIEVTNDNK
| | .|. . . ||.. .|. ||. .|| |. .| ||||.|. |. .|.| .| . ..| ..| . |. | | ..|..||.. .
PihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstg
AGDKQQVKQYQITNWDSTGkmtNPQTILLVIEEMYRTqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. . | || ..| | |.. . . | |. . ||||||. .||| | .. .. ... |.. . || | .. .|||
kfatrtvthyqysewtdrg...vPkshaelfdlmelv..kksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqt
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 913-1096 | 7.6e-25 | 82.8 | In-house | 1-135 (152) | alignment | ||
Range on Protein: 913-1096
Range on HMM: 1-135/152.0
FINGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWsngklgeynisllneeihnagyierkievtndnkagdkqqvkQYQ
||.||. ...||... |. ||. .||.|. . ..|.||||... |.. . |.||. ||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qyl
ITNWDSTGKMTNPQTILLVIEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteGVIDVFQVLKSQRIQKPGSVQT
..|. | ...| .| ... . . ... . ..|||| |||.....|| . ........ | ..||.|..
hlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpn
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 914-968 | 7.3e-08 | 26.2 | In-house | 229-280 (440) | alignment | ||
Range on Protein: 914-968
Range on HMM: 229-280/440.0
INGYKEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENEndqEVCYQYWS
..|| |.||| .. |. | .||... | ....|.|| | |. | ||
fegyskknafiatqmpldstvldfwrlvhdyristiimlnqlnd...ktcsiywp
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 918-1093 | 1.2e-12 | 42.4 | In-house | 2-186 (199) | alignment | ||
Range on Protein: 918-1093
Range on HMM: 2-186/199.0
KEKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKL--GEY-NISLLNEEIH-NAGYIERKIEVTNDNKAG-DKQQVKQYQ
| .. .| .. |. .| .||.|. . |||. ... | . ||. . |.| ..|. . | .. | . .||. | ... .||
kgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
ITNWDSTgkmTNPQTIL-----LVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGS
.| | | |. | . |. . . .. ..||||| | . .| | . . || |.|.|.| | | . |
ftswkek...ttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgi
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 919-1093 | 1.7e-12 | 42.0 | In-house | 2-185 (198) | alignment | ||
Range on Protein: 919-1093
Range on HMM: 2-185/198.0
EKKAFIIAESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKL--GEY-NISLLNEEIH-NAGYIERKIEVTNDNKAG-DKQQVKQYQI
.. .| .. |. .| .||.|. . |||. ... | . ||. . |.| ..|. . | .. | . .||. | ... .||.
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
TNWDSTgkmTNPQTIL-----LVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGS
| | | |. | . |. . . .. ..||||| | . .| | . . || |.|.|.| | | . |
tswkek...ttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgi
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 925-1067 | 1.1e-13 | 45.7 | In-house | 42-177 (263) | alignment | ||
Range on Protein: 925-1067
Range on HMM: 42-177/263.0
IaespMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG---KLGEYNISLLNEEIHNaGYIERKIEVTN--DNkAGDKQQVKQYQITNWDST
. . .| .|...| . . .|||| ||...| | .|. |. |... .. . . . .|... .. ..||.|. . | .
l....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs.dvllktlellstlge.KkkthtvkhysykgWiek
GKMTNPQTILLVIeemyRTQRKRgnTSIVVHCSDTVGRSAMFCAAATT
.... || .. . |. |.||||| .|||| | | .
ndpelareilnil....kvarns..kslvvhcstGiGrsaafsvaElv
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 925-1067 | 1.4e-13 | 45.5 | In-house | 39-171 (255) | alignment | ||
Range on Protein: 925-1067
Range on HMM: 39-171/255.0
IaespmfnTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNGKLGE---YNISLLNEEiHNAGYIERKIEVTNDNK-AGDKQQVKQYQITNWDSTG
. | .|...| . . .|||| .|...| | .|. | . .... . | . | .|.| ..|| |. . |
l.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk.ssadvvlrtleitstlgekkkthtvkhysykGWiekn
KMTNPQTILLVieemYRTQRKRgnTSIVVHCSDTVGRSAMFCAAATT
... || . .. |. |.||||| .|||| | |
aPelareilni....lkvvrds..ksvvvhCstGiGrsaafvlaelv
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 926-1096 | 2.4e-15 | 50.8 | In-house | 96-273 (302) | alignment | ||
Range on Protein: 926-1096
Range on HMM: 96-273/302.0
AESPMFNTARNFWKMIDDRNVTAIVMLCQENENDQEVCYQYWSNG-----KLGEYNISLLNEEIHNAGYIE------RKIEVTNDNKAG-DKQQVKQYQI
| .| .| .|.. ||. .| ||. |.... | .|.|. |.|.| . .. . . . . . ..|..|..| |. |. .
pivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilaf
TNWDSTGKMTNPQTILLVIEemYRTQRKrgnTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. | | ...| | .. . | ....|||| |||. . | |. |... | |. .... | . |.||.
sawpdhGapkeaytaldilk..fcesyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqd
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 939-1096 | 3.2e-11 | 38.7 | In-house | 23-130 (144) | alignment | ||
Range on Protein: 939-1096
Range on HMM: 23-130/144.0
KMIDDRNVTAIVMLCQENENDQEVCYqywsngklgeynisllneeihnagyierkievtndnkagdkqqVKQYQITNWDSTGKMTNPQTILLVIEEMYRT
... . ..|... |. | |.. . .. . ||. ..|. | . .. .| ..| . .
ellkklgittvinlteeyepeflere...........................................giqylhlpwpDhgvpdllellleflefieea
QRkrGNTSIVVHCSDTVGRSAMFCAAATTInkckTEGvIDVFQVLKSQRIQKPGSVQT
.. . ..|||| |||.....|| . ..| ......|. | . ||.|..
le..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpn
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 993-1096 | 1.1e-10 | 36.9 | In-house | 33-128 (145) | alignment | ||
Range on Protein: 993-1096
Range on HMM: 33-128/145.0
KIEVtNDNKAGDKQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKrgNTSIVVHCSDTVGRSAMFCAAATTINkcktEGvIDVFQVLKSQRIQKPG
. . ... . .... ||. ..|. | . ....| ..| . . ... . ..|||| |||.....|| . .| ......|. | | ||
vlnl.tselellerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrpg
SVQT
.|..
avpn
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1003-1065 | 3.6e-06 | 21.0 | In-house | 212-283 (350) | alignment | ||
Range on Protein: 1003-1065
Range on HMM: 212-283/350.0
GDKQQVKQYQITNWDSTGKMTNPQTILLVIE--------EMYR--TQRKRGnTSIVVHCSDTVGRSAMFCAAA
| | | |. || . . ||. || ..| . . . .|. ..|.|||| ||| ....
sdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnars.spilvhCsaGvGrtGtlvtlD
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1005-1096 | 5.9e-11 | 36.3 | In-house | 88-179 (440) | alignment | ||
Range on Protein: 1005-1096
Range on HMM: 88-179/440.0
KQQVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
. .|||. | | .| .|... .| | || ..|||| .||... | . . ..| ||.| ...| | ..| |||
srtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqt
|
|||||||||
| PTPc_DSPc_SM00012 | 1007-1096 | 1.4e-19 | 65.6 | In-house | 1-92 (105) | alignment | |||
Range on Protein: 1007-1096
Range on HMM: 1-92/105.0
QVKQYQITNWDSTGKMTNPQTILLVIEEMYRTQRKRG-NTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQT
.||.|..|.| .|. .... || ..... . ..|.. ....|||||. |||...|.|... ......| . .|.||..|. | |.||.|||
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqt
|
|||||||||