Gene PTPRD-28 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP082_AA protein Get Run
AqueP082_AA_849-1037 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
fn3 Fibronectin type III domain 467-539 4.4e-14 45.6 Pfam-A 10-84 (85) alignment 
Range on Protein: 467-539
Range on HMM: 10-84/85.0
ARTPTRINIVWNPPTIPNGIITVYEISYRESTSTS---PYNITNTTNtNYGIFGLIPNTSYTIGVRAYTSIGPGEW
..|.| ... |.||. ..| || ||. |||.....    .....||. .. . || |.|.|.. |.|..  | |..
evtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngagegpe
Ig_3 Immunoglobulin domain 737-811 6.1e-07 21.6 Pfam-A 1-75 (75) alignment 
Range on Protein: 737-811
Range on HMM: 1-75/75.0
KPVIEEFPSNMTTEEGCqVLLKVKVKDTS-KPSFNWYHNGELVTDDYAHELRGDGSLLLVSVEEKHKGTYRFVANN
||||   ||...|..|  | |   ..... .|.. ||  .. . .       ....| . || ... |||. ||.|
kPvisvspsptvtsggn.vtLtCsaeggpppptisWyietppelqgsegssssestLtissvtsedsGtYtCvasN
Ig_2 Immunoglobulin domain 737-824 7.2e-07 21.2 Pfam-A 1-80 (80) alignment 
Range on Protein: 737-824
Range on HMM: 1-80/80.0
KPVIEEFPSNmtTEEGCQVLLKVKVKDTSKPSFNWYHNGELVTDDYAHelrgdgsLLLVSVEEKHKGTYRFVANND-AGTVSQQVVLTV
|||... |..   .||..| |  ....  .|.. ||..||...   .        |.. .|.....|||. .| |.  ...|. | .||
kpvlsapptv..vtegenvtLtCqapgnptpkvqwykdgeelsqsqna.......lfipnvsaedsGtYtCrasnsegskqsnsvevtv
I-set Immunoglobulin I-set domain 738-824 7.4e-14 43.3 Pfam-A 1-90 (90) alignment 
Range on Protein: 738-824
Range on HMM: 1-90/90.0
PVIEEFPSNMTTEEGCQVLLKVKVKDTSKPSFNWYHNGELVTDDYAHELRGDG---SLLLVSVEEKHKGTYRFVANNDAGTVSQQVVLTV
|.... .......|| .| |...|. . .||..|...|. .. .  .... ..   .| . .||.. .|.|. .|.| ||...... |.|
pkftqklkdvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtckatnsagkaeakaeLkV
0051299 (Phosphotyrosine protein) phosphatases II 845-1036 5.6e-40 133.0 In-house 3-286 (288) alignment 
Range on Protein: 845-1036
Range on HMM: 3-286/288.0
NLIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGhkDCPNEYINACYVDR-------------
. |.| .. |.| . .|.|. ... .| .| |    ......| | |.  ||. .|. || .|. |....|  . .. |||| |.|              
teisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgP

----------------------------------------------------------------------------------SVTQFQITNWDSTGEVKN
                                                                                   ||.|. |||   |   .
lpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpds

PQTILMIMEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
|. .| ....... ..  |.  .|||||. |||...|.|. . ..  ..||..||....|  | |.||.|||..||. .....| ||
pellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
subfamily_PTPRB_pd Subfamily PTPRB 845-930 2e-10 35.2 In-house 5-88 (293) alignment 
Range on Protein: 845-930
Range on HMM: 5-88/293.0
NLIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
. | . .| ..|.. .|. . ||. .. .| . .....|..  .. |.  ||. ||. ||..|. | .......  ..|||| |..
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesg..sDYinanyip
subfamily_PTPRA_pd Subfamily PTPRA 845-930 2.8e-07 24.7 In-house 12-95 (330) alignment 
Range on Protein: 845-930
Range on HMM: 12-95/330.0
NLIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
  .|| .. . .    |   ..|. .|  | .|. . .. .     ||  ||. ||. || .|. | ...|...   .|||| ..|
fplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGvee..sdyinasfid
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 846-930 5.5e-41 135.3 In-house 1-85 (290) alignment 
Range on Protein: 846-930
Range on HMM: 1-85/290.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCPNEYINACYVD
||||..||.|||||||||.|.|..||.|||||||||.|||||..|||||||||||||||.||||||||||||||.||||||||..
lipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyik
0045450 (Phosphotyrosine protein) phosphatases II 846-1036 2.2e-35 118.3 In-house 8-304 (307) alignment 
Range on Protein: 846-1036
Range on HMM: 8-304/307.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGES--EHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkDCPNEYINACYV--------------
.|.. .. ..|.  ......... .| .| | .    .. ...|.| || .||. .|. || .|. | ...|. . .. |||| ||              
fidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlk

---------------------------------------------------------------------------------------DRSVTQFQITNWD
                                                                                        | ||.|. |.| 
rkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwp

STGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
 .|  ......| ..||. . ...  ... ..||||. |||...|.|| . .   ..||.   .|.....|  | |.||.||. .||. . ...| .|
dhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 846-930 3.7e-29 96.6 In-house 1-80 (287) alignment 
Range on Protein: 846-930
Range on HMM: 1-80/287.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDS-GESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRpisghkDCPNEYINACYVD
||||..||.|||.|||||.| ||.||..|.. ...|..||......|| .||...|.|.|..|. |.      .. ..||||...|
lipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfid
subfamily_PTPRD_pd Subfamily PTPRD 846-930 4.1e-15 50.4 In-house 4-85 (564) alignment 
Range on Protein: 846-930
Range on HMM: 4-85/564.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGeSEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCpnEYINACYVD
 ||| .. ..||. .|... .|....  ...| .......   | ||  ||.|||| ||..|. |... |....  .|||| ..|
pipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegs..DYINAsfid
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 846-930 2.9e-11 38.0 In-house 4-85 (319) alignment 
Range on Protein: 846-930
Range on HMM: 4-85/319.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEhSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
 |.| .. . . . ...|.  .. .|..|. .... ...    . ||  ||. ||. ||  |..| .. | ..   .|||| ..|
eievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgveg..sdyinasfid
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 846-930 3.2e-09 31.4 In-house 3-83 (305) alignment 
Range on Protein: 846-930
Range on HMM: 3-83/305.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGesEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKdcPNEYINACYVD
 | . .. ... . ... .. ...|. .| .   |.|. || .  ||  ||...|...|..|| |.. . ..   ..||||.|||
iialddlaayikearvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvd
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 846-930 2.2e-07 25.1 In-house 5-86 (315) alignment 
Range on Protein: 846-930
Range on HMM: 5-86/315.0
LIPVGQFGKFVANGHAKGKERFKTQFMMLDSGEsEHSVTVGLSPSNKLLNRFANIVVYDENRITLrPISgHKDCPNEYINACYVD
 ||. |.  .||. .|  |. || ..  .  |.  | . |     ||  ||. ||. ||. |. | |.   .|   .|.|| ..|
pipldqlityvaqkkastkngfkqdyesipggq.lhpldvakkienkqknryiniiaydksrvql.pll.endphsdyvnanfid
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 846-930 4.1e-06 20.5 In-house 3-82 (392) alignment 
Range on Protein: 846-930
Range on HMM: 3-82/392.0
LIPVGQFGKFVANGHAkgKERFKTQFMMLDSGEsEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
 ||| ||  || . .      |  .|  | . .  .  ||.  . |.  ||. ||. ||..|. |  |    |  ..|.|| |..
pipvaqfpafveknrh..salffeefhdlpgpd.iypqtvaqkeinlkknryknilpydsarvkleviddipd..sdylnasyip
0043336 (Phosphotyrosine protein) phosphatases II 847-1036 7.8e-33 109.5 In-house 2-277 (278) alignment 
Range on Protein: 847-1036
Range on HMM: 2-277/278.0
IPVGQFGKFVANGHAKGKERFKTQFMMLDSGESeHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVDRS--------------
|.| .. |.... ....| ... .|  |.|     . ...|.| || .||. .|. || .|. | ...|. |  . |||| |||                
isvkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdld..sdYinAsyvdgynvprkfiatqgPlp

----------------------------------------------------------------------------VTQFQITNWDSTGEVKNPQTILMI
                                                                            ||... ..|   |   .....| .
etvedFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldf

MEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.... . ..   |. ..||||. |||...|.|. . ..  ..|| .|.....|  | |.||.||| .||. .....| ||
lkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 847-1036 4.4e-26 86.2 In-house 6-194 (440) alignment 
Range on Protein: 847-1036
Range on HMM: 6-194/440.0
IPVGQFGKFVANGhaKGKERFKTQFMMLDSGESEHSVTVGLsPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD----RSVTQFQITNWD
| | .|  .| |   .    |. .. .| || |. |   .| |.||. ||. ||..|| .|. |  . |  |  ..|||| |..    |.. |..   | 
iivadfadyvqnn..rrsrafedewsllpsglsqpsdiasl.pnnkvknryrnilaydhsrvmleevkgvpd..sdyinasyingiesrtlkqyhyqgwp

STGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
  |  |    .| .....  .| | ||  ..||||  .||...  |  . . ..|    ||.| ...| | ..|  ||| .||  ... ||  |
dkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheavlegl
subfamily_PTPRG_pd Subfamily PTPRG 847-930 7.2e-14 45.9 In-house 1-85 (563) alignment 
Range on Protein: 847-930
Range on HMM: 1-85/563.0
IPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEH--SVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCPnEYINACYVD
.|| .| | ||. ||.|. .|. .|  | |   ..   ..    |.||  ||  ||| ||. |..|.|..|.|.   .|||| |.|
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyid
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 847-930 1.1e-11 39.4 In-house 2-83 (318) alignment 
Range on Protein: 847-930
Range on HMM: 2-83/318.0
IPVGQFGKFVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
|.| .. . |.. ...|.  ..... .|.  |.. . .  |.| ||  ||.|||. ||. |. |....|...   .|||| |.|
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeeg..sDyinanyid
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 847-929 5.1e-06 20.6 In-house 3-80 (315) alignment 
Range on Protein: 847-929
Range on HMM: 3-80/315.0
IPVGQFGKFVANGhaKGKERFKTQFMMLDSGEsEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYV
||| ||  || .   .    |  .|  |   .  .  .|.  . |   ||. ||. .|..|. |  |  . |  ..|||| |.
ipvaqfpafvnkn..rhtalfseefhdlpdPd.iyrqrvaretinfkknryknilPldsarvkleviddsPd..sdyinasyi
0039614 (Phosphotyrosine protein) phosphatases II 848-1040 5.3e-34 113.4 In-house 15-293 (297) alignment 
Range on Protein: 848-1040
Range on HMM: 15-293/297.0
PVGQFGKFVANGHAKGKERFKTQFMMLDSGESEhsVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkDCPNEYINACYVD-----------------
|.. .  ..   .|..| .....|..| |   .   ...|.| || .||. .|. || .|. | |. |. | .. |||| |||                 
plsvldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgv.dldsdYinAsyvdgydlltrkfIatqgPlp

-----------------------------------------------------------------------RSVTQFQITNWDSTGEVKNPQTILMIMEE
                                                                       | ||.|| |.|   |   .....| ..|.
etvedFwrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflel

MYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFE
. . ...  ... ..||||. |||...|.|| . .. ...|| .||....|  | |.||.||| .||. .....| .|  . 
vrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
subfamily_Sponge-PTP3_pd Subfamily Sponge-PTP3 848-931 6.4e-08 26.7 In-house 6-83 (95) alignment 
Range on Protein: 848-931
Range on HMM: 6-83/95.0
PVGQFGKFVANGHAKGKERFKTQFMMLDSgESEHSVTVGLSPSNKLLNRFANIVVYDENRITLrpiSGHKDcpNEYINACYVDR
 |  |   | . |..  . |  .|  .    |  . ||| | .|   ||| ||. ||  |..|   . ..|   .|||||.|| 
hvsvfhshvlemhsnsdqefdnefksism.tsgapytvgsseanipknrflnifpydatrvvl...ttkrd..sdyinacfvdg
0040438 (Phosphotyrosine protein) phosphatases II 851-1043 1.3e-35 118.7 In-house 4-283 (317) alignment 
Range on Protein: 851-1043
Range on HMM: 4-283/317.0
QFGKFVANGHAKGKERFKTQFMMLDSGESEhSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGhkDCPNEYINACYVD--------------------
.. ...   ..... ... .|..|.|   . . .|.. | || .||. .|. || .|. | |..|  | .. |||| |||                    
dlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntve

-----------------------------------------------------------------------RSVTQFQITNWDSTGEVKNPQTILMIMEE
                                                                       | ||.|. |.|.  |  ..|...| ..|.
dFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldflea

MYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYS
. . .. .... ..||||. |||...|.|| . .. ...|| .||....|  | |.||.||| .||. . ...| ||  ..|. 
vreale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltle
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 852-930 2e-10 35.4 In-house 14-93 (298) alignment 
Range on Protein: 852-930
Range on HMM: 14-93/298.0
FGKFVANGHAKGKERFKTQFMMLDSGES---EHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCpnEYINACYVD
. |..|  ..|.  .....|  |.|..|   |.. .|. .|.||  ||.|.|. .|  |. |. ... ...  .|||| ...
lqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadees..dYiNAsflh
0050432 (Phosphotyrosine protein) phosphatases II 854-1043 3e-39 130.6 In-house 33-306 (308) alignment 
Range on Protein: 854-1043
Range on HMM: 33-306/308.0
KFVANghAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLrpisghkDCPNEYINACYVDRS---------------------
|.. .  |... .....|. | |    .. .|.| | || .||. .|. || .|. |       | .. |||| |||                       
kllek..aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.......degsdYInAsyvdgyssklprkfIatqgPlpntved

---------------------------------------------------------------------------VTQFQITNWDSTGEVKNPQTILMIM
                                                                           ||.|. |||   |   .|. .| ..
FwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldfl

EEMYRTQrkrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYS
|.. ...   ..  ||||||. |||.. |.|. . ..  ..|| .|||...|  | |.||.|||..||. .....| || ...|. 
elvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltkl
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 854-929 4.8e-07 24.2 In-house 12-84 (325) alignment 
Range on Protein: 854-929
Range on HMM: 12-84/325.0
KFVANGHAKGKERFKTQFMMLDSGESeHSVTVGLSPSNKLLNRFANIVVYDENRITLRPIsgHKDCPNEYINACYV
..| . .|. .. |  .| .| | ..  . .|   | ||  ||| |.| .|..|. |     ..|   .|||| |.
ehvekkkaqdqdgfahefgllpsddg.iakkvamkpenkaknrfknvvaldksrvvletk..kddpssdyinasyl
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 855-930 1.2e-10 35.9 In-house 11-84 (288) alignment 
Range on Protein: 855-930
Range on HMM: 11-84/288.0
FVANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDcpNEYINACYVD
 ||. .|.... |. ..  | . |...|||.|  . |.  ||. ||. |||.|. |.     ..  ..|||| |.|
kvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeag..aDYinasyid
subfamily_Ptp69D_pd Subfamily Ptp69D 856-929 6.6e-09 30.3 In-house 13-84 (307) alignment 
Range on Protein: 856-929
Range on HMM: 13-84/307.0
VANGHAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCpnEYINACYV
. . . . .. ..  . .| . |...| .|.    |.| ||. .|. .|..|. |..| |..|   .|||| ..
lksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkeds..dYinasfi
subfamily_PTPN6_pd Subfamily PTPN6 858-933 9.2e-08 26.4 In-house 19-93 (306) alignment 
Range on Protein: 858-933
Range on HMM: 19-93/306.0
NGHAKGKERFKTQFMMLDSGESEH--SVTVGLSPSNKLLNRFANIVVYDENRITLRpisGHKDCPNEYINACYVDRSV
... ..|. |. .|  |.  |...  | . |  |.||  ||. ||. .|..|..|.    ..   ..|||| |....|
eeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkev
0047943 (Phosphotyrosine protein) phosphatases II 860-1036 1.2e-35 118.8 In-house 7-272 (273) alignment 
Range on Protein: 860-1036
Range on HMM: 7-272/273.0
HAKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLrpisghKDCPNEYINACYVDR----------------------------
...|. ... .| .| |   ... .|.| | || .||. .|. || .|. |      .| .. |||| |||                             
kllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweq

------------------------------------------------------------------SVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQR
                                                                   ||.|. |.|   |   ... .| ..|.. ....
nvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkale

KR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.  .|. .|||||. |||...|.|. . ..  ..|| .||....|  | |.||.|||..||. . ...| ||
alpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
subfamily_PTPN23_pd Subfamily PTPN23 860-931 4.6e-06 20.7 In-house 10-77 (288) alignment 
Range on Protein: 860-931
Range on HMM: 10-77/288.0
HAKGKERFKTQFMMLDSGESEHS--VTVGLSPSNKLLNRFANIVVYDENRITLRpisGHKDcpnEYINACYVDR
  .||  ....|  |.. . ...   .. ..  .   ||. .|. ||.||..||   |.||   .||||..|  
mldgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr...gskD...DYinAsfvkd
0036941 (Phosphotyrosine protein) phosphatases II 861-1043 5.1e-36 119.9 In-house 9-284 (297) alignment 
Range on Protein: 861-1043
Range on HMM: 9-284/297.0
AKGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLrpisghKDCPNEYINACYVD------------------------------
.... .....|. |..     | .|.|.| |. .||. .|. || .|. |      .| .. ||||.|||                              
llflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqn

-----------------------------------------------------------------RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQR
                                                                 | ||.|..|.|.  |   .|...| ..|.. . ..
vtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlk

KR-GNTSIVVHCSDTVGRSAMFCAAATTINKCK---TEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYS
.  ... ..||||. ||||..|.|| . ..  .   .|| .|.....|. | |.||.|||..||. . ...| .| ...|. 
llpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltke
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 861-930 8.1e-13 42.7 In-house 11-79 (301) alignment 
Range on Protein: 861-930
Range on HMM: 11-79/301.0
AKGKERFKTQFMMLDSGESeHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCPNEYINACYVD
|| ...|. |.  |..||. .| ||||| .|| |||| ||.|||.|||.|.| .  . | .||||| |.|
akhsnkfeeqykelkeged.ksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyid
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 862-930 2.9e-08 28.2 In-house 12-78 (281) alignment 
Range on Protein: 862-930
Range on HMM: 12-78/281.0
KGKERFKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHKdcPNEYINACYVD
. .. |....  | . . ... |   .. |.| ||. ||| ||  |... | . .|   ..|||| .|.
ndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenk..ntDYinanfvp
0046845 (Phosphotyrosine protein) phosphatases II 867-1044 9.8e-37 122.3 In-house 2-282 (284) alignment 
Range on Protein: 867-1044
Range on HMM: 2-282/284.0
FKTQFMMLDSGESEH--SVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkDCPNEYINACYVDRS--------------------------------
.. .|..| |    .  |..|.| | |. .||. .|..|| .|. |....|. .  ..|||| |||                                  
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgd.ledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq

------------------------------------------------------------------VTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRK
                                                                  ||.|..|.|   |   .|. .| ..... . ...
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen

-RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEG---VIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSFETYSN
  |.  ||||||. |||...|.|. . ..  ..||   ..||....|  | |.||.|||..||. .....| || .. |. .
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltlle
DSPc_SM00195 867-930 1.1e-08 30.1 In-house 2-63 (263) alignment 
Range on Protein: 867-930
Range on HMM: 2-63/263.0
FKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkdCPNEYINACYVD
.|..|  |.. .|....| .  ..||  ||. ||..||..|. | .. ..   ...|||| |..
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyik
PTPc_SM00194 867-930 1.1e-08 30.1 In-house 2-63 (263) alignment 
Range on Protein: 867-930
Range on HMM: 2-63/263.0
FKTQFMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITLRPISGHkdCPNEYINACYVD
.|..|  |.. .|....| .  ..||  ||. ||..||..|. | .. ..   ...|||| |..
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyik
0045098 (Phosphotyrosine protein) phosphatases II 871-1037 3.5e-28 94.2 In-house 13-273 (278) alignment 
Range on Protein: 871-1037
Range on HMM: 13-273/278.0
FMMLDSGESEHSVTVGLSPSNKLLNRFANIVVYDENRITlrpisghkdcpnEYINACYVD----------------------------------------
|  | .  .  ..|..| ..|. .||. .|. || .|.             .|||| |.|                                        
fefllllgipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelve

-----------------------------------------------------RSVTQFQITNWDSTGEVKNP--QTILMIMEEMYRTQR----------
                                                     | ||......|.  |   .|  . .| ..|.. . ..          
lgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssl

--KRGNTSIVVHCSDTVGRSAMFCAAATTINKCktEGVIDVFQVLKSQRIQKPG-SVQTVQQYQGIFQIVLTYLD
    ... ..||||  |||.....|| . .  .  ||..|.....|  | |.|| .||. .||. ... .| .| 
llldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
0049772 (Phosphotyrosine protein) phosphatases II 879-1043 8.9e-15 50.7 In-house 34-287 (314) alignment 
Range on Protein: 879-1043
Range on HMM: 34-287/314.0
SEHSVTVGLSPSNKLLNRFANIVVYDeNRITLrPISGHKDCPneYINA----------------------------------------------------
.|....|.  . |.  ||. .|. .| ||  | |  .....   ||||                                                    
peltilvadlflnrdknryldilpad.nrvil.pglpvsgsd..yinasyvdgflkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrd

--------------------------------------------CYVDRSVTQFQITNWDStGEVKNPQTILMIMEEMYRTqrkRGNTSIVVHCSDTVGR
                                             .. | . ..  ....  |..  .. .. ..| . .    . .. ..|||.. .||
evladelsrLdaAlgKtpllildgngneptaadlellkeelydpelferlgikylripvpD.gsaplledfdeflefieea...dkggpvlvHCkaGkgR

SAMFCAAATTINKCkteGViDVFQVLKSQRIQKP-----GSVQTVQQYQGIFQIVLTYLDSFETYS
.. |..||  . ..   || .. ..|.  | . |     |.... .||. |....| ||. .....
tgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkflkkfy
subfamily_PTPN14_pd Subfamily PTPN14 881-935 2.7e-06 21.6 In-house 39-90 (300) alignment 
Range on Protein: 881-935
Range on HMM: 39-90/300.0
HSVTVGLSPSNKLLNRFANIVVYDENRITLRPisgHKDCPNEYINACYVDRSVTQ
  ....  | |.  ||| ... |..||. | |    |.  ..||||  .  ||. 
allstaklpenaeknrfkdvlPyednrvelsp...tkenstgyinassikvsvgg
0040439 (Phosphotyrosine protein) phosphatases II 883-1036 1e-27 92.7 In-house 3-246 (249) alignment 
Range on Protein: 883-1036
Range on HMM: 3-246/249.0
VTVGLSPSNKLLNRFANIVVYDENRITLRPISGhkDCPNEYINACYVD----------------------------------------------------
..|.| | || .||. .|. || .|. | ...|    .. |||| |.|                                                    
ysvallpenkdknrypdilpydhsrvklsilpg..lflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqyw

---------------------------------------RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAA
                                       | |...|.|.|  .|  ......| ..|..   ...   .. ..||||. |||...|.|| 
plggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaay

TTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
. ..  ..|. .|.....|  | |.||.||. .||. . ...| .|
lmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
0037934 (Phosphotyrosine protein) phosphatases II 884-1035 9.8e-22 73.1 In-house 3-241 (243) alignment 
Range on Protein: 884-1035
Range on HMM: 3-241/243.0
TVGLSPSNKLLNRFANIVVYDENRITLrpisghKDcpNEYINAC--------------------------------------------------------
...|.| |.  ||. .|. || .|. |      ..  . ||||                                                         
siallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw

-----------------------------------YVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRK-------RGNTSIVVHCSDTVGRSAM
                                   .. | |.... ..|   |   .|. .| ...|..  ...        ..  ..||||  |||...
pgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGt

FCAAATTINKCkteGvIDVFQVLKSQRIQKPG-SVQTVQQYQGIFQIVLTY
..|| . . ..   | .|.....|  | |.|| .||| .||. . ...| .
liaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallel
0042113 (Phosphotyrosine protein) phosphatases II 885-1036 5.5e-29 96.7 In-house 3-243 (245) alignment 
Range on Protein: 885-1036
Range on HMM: 3-243/245.0
VGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCPneYINACYV-------------------------------------------------------
|.| | || .||. .|. || .|. | |..|. |..  ||||.||                                                       
vallpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl

------------------------------------DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTI
                                     | |.... ..|.  |.  .....| ..|.. . ... .|. ..||||. |||...|.|| . .
gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylml

NKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.  ..|. .......|  | |.||.||| .||. . ...| .|
eqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 885-930 1.8e-06 22.3 In-house 3-46 (250) alignment 
Range on Protein: 885-930
Range on HMM: 3-46/250.0
VGLSPSNKLLNRFANIVVYDENRITLRPISGHKDCpnEYINACYVD
|.  |.||  ||.|.|. .|. |. | . .| |..  .|||| ...
vakkpqnkeknryadiialdssrvvLekekgdkes..dyinasflh
0041856 (Phosphotyrosine protein) phosphatases II 891-1035 4.5e-15 51.2 In-house 1-170 (182) alignment 
Range on Protein: 891-1035
Range on HMM: 1-170/182.0
NKLLNRFANIVVYDENRitlrpisghkdcPNEYINACYVD------------------------------------------------RSVTQFQITNWD
|. .||. .|. || .|            .. |||| ...                                                | ..|.. ..|.
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwp

STGEVKnPQTILMIMEEMYRtqrkrGNTSIVVHCSDTVGRSAMFCAAATTINKckteGvIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
  |    ....| ..||...      .  ..||||  |||.....||   . .    | .......|  | ..||.|.| .||. . ...| .
Dhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitpnqyfflqlallel
0051429 (Phosphotyrosine protein) phosphatases II 912-1039 3.5e-14 48.6 In-house 76-228 (272) alignment 
Range on Protein: 912-1039
Range on HMM: 76-228/272.0
PISGHKDCPNEYIN-------------------------ACYVDRSVTQFQITNWDSTGEVKNPqtILMIMEEMYRtqrkrgNTSIVVHCSDTVGRSAMF
|| .. . . .|..                              | |.... |.|   |  ...  .| ..|.. .      .  ..||||  ..|....
pilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtv

CAAATTINKCKTEGVID--------VFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSF
.|.   .     | ..|        ......  | | ||.||| .||. .....| .|.|.
vallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsl
0043147 (Phosphotyrosine protein) phosphatases II 923-1029 2.5e-15 52.1 In-house 55-154 (172) alignment 
Range on Protein: 923-1029
Range on HMM: 55-154/172.0
YINACYVDRSVTQFQITNWDSTGEVkNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteG-ViDVFQVLKSQRIQKPGSVQT
. .. .. |.. |.. ..|.  |   ... .| ..| ... . .. .  ..||||  |||.....||   .        . .......  | ..||.||.
lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqn

VQQYQGIF
 .||. . 
psqyrfly
0049260 (Phosphotyrosine protein) phosphatases II 924-1029 4.9e-13 44.5 In-house 55-143 (152) alignment 
Range on Protein: 924-1029
Range on HMM: 55-143/152.0
InacyvdrsvtQFQITNWDSTGEVKNPQTILMIMEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTInkckteGVIDVFQVLKSQRIQKPGSVQTVQ
|          |.. ..|.  |  ...| .|.... . .  ... .  ..||||  |||.....||   .        ........  | ..||.|.. .
i..........qylhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpg

QYQGIF
|.. ..
qlrfly
0036282 (Phosphotyrosine protein) phosphatases II 925-1030 6.6e-18 60.4 In-house 61-164 (174) alignment 
Range on Protein: 925-1030
Range on HMM: 61-164/174.0
NACYVDRSVTQFQITNWDSTGEVKNPQtILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKtEGVIDVFQVLKSQRIQKPGSVQTVQQ
.  .  |.. |.. ..|.  |.   .. .| ....... . . ..  ..||||  |||.....||   .   . |...|........| |.||.||| .|
lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQ

YQGIFQ
|. . .
yrflyy
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 927-1037 2.9e-18 60.9 In-house 157-269 (274) alignment 
Range on Protein: 927-1037
Range on HMM: 157-269/274.0
CYVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNT--SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQ
.   |||. .  |.|  .   ....|.| ...|. ...... .   ..|||||  .||  .| |.  .... . |.|.||...    |... | ||| .|
lerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseq

YQGIFQIVLTYLD
|. |....  || 
yelihralclylk
0048179 (Phosphotyrosine protein) phosphatases II 927-1029 3.1e-12 41.9 In-house 43-138 (144) alignment 
Range on Protein: 927-1029
Range on HMM: 43-138/144.0
CYVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTInkckTEGvIDVFQVLKSQRIQKPGSVQTVQQYQ
 .. | ..|.. ..|.  |    .. .| ..| . . ..   .  ..||||  |||.....||   .    ..| ......|.  | . ||.|.. .|..
efleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlr

GIF
 . 
fLl
0048076 (Phosphotyrosine protein) phosphatases II 928-1033 5.5e-13 44.3 In-house 42-140 (145) alignment 
Range on Protein: 928-1033
Range on HMM: 42-140/145.0
YVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKrgNTSIVVHCSDTVGRSAMFCAAATTINkcktEGvIDVFQVLKSQRIQKPGSVQTVQQYQG
.. | ..|.. ..|.  |.   ....| ..| . . ...  .  ..||||  |||.....||   .     .| ......|.  | | ||.|....|.. 
llerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsleealelvrsqrpgavpnpgqlrf

IFQIVL
... .|
lyefel
0044763 (Phosphotyrosine protein) phosphatases II 928-1032 3.1e-09 32.2 In-house 70-167 (178) alignment 
Range on Protein: 928-1032
Range on HMM: 70-167/178.0
YVDRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRkRGNTSIVVHCSDTVGRSAMFCAAATTINKckteGViDVFQVLKSQRIQKPgSVQTVQQYQG
....   |.. ....  |.   .. .| ..| . . .  . .  ..||||  ||||....||   .      |. .......  | ..|  |..  |.. 
wpeeagiqylhipipDhgvpdllehflefvefieeald.ekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgqlrq

IFQIV
. .. 
Lyefe
subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 928-1025 1e-08 29.3 In-house 178-270 (301) alignment 
Range on Protein: 928-1025
Range on HMM: 178-270/301.0
YVDRSVTQFQITNWDSTGEVKNPQTILMIMEeMYrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
.  |.|| .| ..|   |  |    .  .|| .     |. .  ||||||. .|||  | ..    .. ...  |.. . ||  | ..  .|||..| 
fatrtvthyqysewtdrgvPkshaelfdlme.lv....kksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsql
subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 928-1031 3.4e-07 24.6 In-house 91-198 (198) alignment 
Range on Protein: 928-1031
Range on HMM: 91-198/198.0
YVDRSVTQFQITNWD--STGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGSVQTV
   | ....|.| |   .| .|     ...   |. .   .  .. ..|||||  | . .| |    .    . ||  |.|.|.| |  |  . | . ..
pstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiissl

QQYQGIFQI
|.|. |.|.
qhynfiyqv
subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 928-1031 3.5e-07 24.6 In-house 92-199 (199) alignment 
Range on Protein: 928-1031
Range on HMM: 92-199/199.0
YVDRSVTQFQITNWD--STGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTeGVIDVFQVLKSQRIQKPGSVQTV
   | ....|.| |   .| .|     ...   |. .   .  .. ..|||||  | . .| |    .    . ||  |.|.|.| |  |  . | . ..
pstreishyqftswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheeskt.svvdlfevakrlrqarcgiissl

QQYQGIFQI
|.|. |.|.
qhynfiyqv
subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 929-1029 6.3e-09 29.7 In-house 186-281 (302) alignment 
Range on Protein: 929-1029
Range on HMM: 186-281/302.0
VDRSVTQFQITNWDSTGEVKNPQTILMIMEemYRTQRKrgnTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGI
| ..|  .. . |   |  |...| | |.   .    |   ....||||  |||.  . |    |. |... | |. ....  |  . |.||. ||   .
vkktvdilafsawpdhGapkeaytaldilk..fcesyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyl

F
.
l
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 930-1041 1e-31 105.2 In-house 177-288 (305) alignment 
Range on Protein: 930-1041
Range on HMM: 177-288/305.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|.|.|.|.|.|   | .. . ..| ..... ..|.|  .....||||..|||. .|.|    ....|.|.|.|||.|||  | .... ||| .||. ..
srtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflh

QIVLTYLDSFET
...  .. ...|
daldelitcgdt
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 930-1044 9.3e-28 92.2 In-house 174-288 (318) alignment 
Range on Protein: 930-1044
Range on HMM: 174-288/318.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
 | | |...|.|  .|  ... ..| .. .  ..|.| |.. ||||||  |||  .|.|  . ... | |...||||. |  | |..  ||| .||. |.
srqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiy

QIVLTYLDSFETYSN
...| .| |..|. .
dvllealasgdtevd
subfamily_PTPN14_pd Subfamily PTPN14 930-1037 2.6e-12 41.3 In-house 182-297 (300) alignment 
Range on Protein: 930-1037
Range on HMM: 182-297/300.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNT--------SIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQT
.|.|  .| |.|   |  ..... |  .||.   .||  ..         ..||||. |||. .   .   |.  ... .||. .||.  | |.   |||
ertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqt

VQQYQGIFQIVLTYLD
. ||. .......||.
laqYkfvYkvlikylk
subfamily_PTPN3_pd Subfamily PTPN3 930-1033 3.9e-12 40.7 In-house 170-272 (280) alignment 
Range on Protein: 930-1033
Range on HMM: 170-272/280.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|...|.| ..|   |  .... .| ..|.. |..|.  .. .|||||  .||. .. .  |.. .  ..  . . ....  | |.   |||..||. . 
erkilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvC

QIVL
. .|
eail
0051082 (Phosphotyrosine protein) phosphatases II 930-1030 2.9e-11 38.7 In-house 57-147 (151) alignment 
Range on Protein: 930-1030
Range on HMM: 57-147/151.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRtqrkRGNTSIVVHCSDTVGRSAMFCAAATTINKcktegvIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.. |....|..|. .|   .....| ..|.. .     .|  ..||||  .||.....|.   . .      ......|.  |.. ||.||. ||.. ..
gievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfql

Q
.
f
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 930-1033 1.7e-10 35.5 In-house 135-237 (239) alignment 
Range on Protein: 930-1033
Range on HMM: 135-237/239.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRtQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.| | |...| |   |  .   ..| .  .. . .   |    |.|||  |||.  |    . . ..| .  .|.|. .|. | ..|  ||| .||  |.
eryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih

QIVL
  ||
lavl
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 930-1033 1.8e-10 35.4 In-house 136-238 (239) alignment 
Range on Protein: 930-1033
Range on HMM: 136-238/239.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRtQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.| | |...| |   |  .   ..| .  .. . .   |    |.|||  |||.  |    . . ..| .  .|.|. .|. | ..|  ||| .||  |.
eryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih

QIVL
  ||
lavl
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 930-1043 3.1e-10 34.5 In-house 175-286 (307) alignment 
Range on Protein: 930-1043
Range on HMM: 175-286/307.0
DRSVTQFQITNWDSTGEvknPQTILMIMEEMYRTqRKRgNTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGI
 |.....| .||   |    ||. |  .. .  . |   .  .|||||  ||||    | .   .|  . .   |. ....  | |.. ..||  ||  .
srtiqhlqwenwpdrgv...pqinltainlleav.ryd.tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylyl

FQIVLTYL-DSF-ETYS
 ...| |. . . ||| 
hrvlleyflelyketye
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 930-1034 5.3e-09 30.0 In-house 173-277 (439) alignment 
Range on Protein: 930-1034
Range on HMM: 173-277/439.0
DRSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|.| ||. . |       .   .|  .  .  .. |.    .|||||  |||.    |   .... |.|  .|.  ..|  | |.   ||.. ||  |.
ertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiy

QIVLT
. || 
navle
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 931-1043 2.5e-65 215.2 In-house 178-290 (290) alignment 
Range on Protein: 931-1043
Range on HMM: 178-290/290.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
.||||.|||||||||.|.||||||...||||.||||||||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||
qsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifq

IVLTYLDSFETYS
|||||||||||||
ivltyldsfetys
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 931-1045 4e-64 211.3 In-house 173-287 (287) alignment 
Range on Protein: 931-1045
Range on HMM: 173-287/287.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
..|.|.|||||||||.|..|||||...||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||..|..
qqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfind

IVLTYLDSFETYSNF
|||.|||||||||.|
ivleyldsfetysdf
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 931-1044 4.4e-37 122.4 In-house 188-301 (301) alignment 
Range on Protein: 931-1044
Range on HMM: 188-301/301.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
..|.|.|.|.|   | |..|.|.|......  .|.| |   .||||||||.|| ..|.   ..  || |||.||||| |. | .||| |.| .||  |..
wdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiyd

IVLTYLDSFETYSN
.. .||   .||.|
vidmylqlnstyan
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 931-1042 8.9e-31 102.2 In-house 185-296 (298) alignment 
Range on Protein: 931-1042
Range on HMM: 185-296/298.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.| |.. |.| . |. .| ...| ..... ..|.. ||....|.||. ||||  |.|  . ... |.| |.|||||.|  |...||.||| .||  |..
revrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiye

IVLTYLDSFETY
.|| .||||...
avlealdsfnde
subfamily_PTPRD_pd Subfamily PTPRD 931-1042 7.7e-28 92.4 In-house 177-287 (564) alignment 
Range on Protein: 931-1042
Range on HMM: 177-287/564.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| |.||. |.| ..|  ......| ..... ... ....  ||||||  |||. .|..    ... |.|...|..|..|  | |..  ||| .||. |..
reVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFihe

IVLTYLDSFETY
..| .|....| 
ailealacgnte
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 931-1044 1.2e-27 91.8 In-house 137-250 (250) alignment 
Range on Protein: 931-1044
Range on HMM: 137-250/250.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| | |.. ..|   |  .. ...| ..... ..|.. ||. ..|.||  ||||  |.|  . ... |.| |.|||.|.|  |...|..|.. .||  ...
rivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvye

IVLTYLDSFETYSN
|.| .|||.| |..
iilkaldsvedyar
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 931-1041 2.4e-26 87.6 In-house 178-288 (319) alignment 
Range on Protein: 931-1041
Range on HMM: 178-288/319.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|..|| |.|   .  .. ...| ..... ....|  .  ||||||. |||   |..   .... | |||.|||.. .  |.|..  ||. .||. |..
RevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiye

IVLTYLDSFET
..| ......|
alleaveagdt
Y_phosphatase Protein-tyrosine phosphatase 931-1033 3.5e-24 80.9 Pfam-A 133-234 (235) alignment 
Range on Protein: 931-1033
Range on HMM: 133-234/235.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|.|...|||   |  ..|. .| ..... ... .  ....|||||. |||...|.|. . ......|. .||.|..|. | |.||.||...||. . .
revkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflyk

IVL
..|
ail
Y_phosphatase Protein-tyrosine phosphatase 931-1033 3.5e-24 80.9 In-house 133-234 (235) alignment 
Range on Protein: 931-1033
Range on HMM: 133-234/235.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|.|...|||   |  ..|. .| ..... ... .  ....|||||. |||...|.|. . ......|. .||.|..|. | |.||.||...||. . .
revkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflyk

IVL
..|
ail
subfamily_PTPRA_pd Subfamily PTPRA 931-1035 7.8e-24 79.2 In-house 191-294 (330) alignment 
Range on Protein: 931-1035
Range on HMM: 191-294/330.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNtSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| |.||  | |   |   .|. .| ..... ..... .. .||||||  |||.  |..  . ... |.|...|||...|. | |.|  ||| .||. |..
rlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiyk

IVLTY
..| |
vlley
DSPc_SM00195 931-1036 7.9e-23 76.5 In-house 158-262 (263) alignment 
Range on Protein: 931-1036
Range on HMM: 158-262/263.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|||.|..||   |  .... .| ...... ....  .. ||||||. |||...|... . ..|...|  .|.|...|. | |.||.||| .||. | .
rkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiye

IVLTYL
..| |.
aileyi
PTPc_SM00194 931-1036 7.9e-23 76.5 In-house 158-262 (263) alignment 
Range on Protein: 931-1036
Range on HMM: 158-262/263.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.|||.|..||   |  .... .| ...... ....  .. ||||||. |||...|... . ..|...|  .|.|...|. | |.||.||| .||. | .
rkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiye

IVLTYL
..| |.
aileyi
subfamily_PTPRK_pd Subfamily PTPRK 931-1034 5.2e-19 63.2 In-house 173-275 (314) alignment 
Range on Protein: 931-1034
Range on HMM: 173-275/314.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| | ||| ..| . .  .. ...| .. ..  .| . ..  ||||||   ||. .|.| .. ..  ..|||.|||.. |. | .|.  |.| .||. |..
revrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiyd

IVLT
..| 
vile
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 931-1037 5.2e-19 62.7 In-house 172-277 (515) alignment 
Range on Protein: 931-1037
Range on HMM: 172-277/515.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| ||||. |.|   |  |. ...| .. |. .... . . ....|||  |||  .....   . . ||  ..|||....  | ..|  ||| .||  |..
rtvtqfhfteWPdkGvpkhtssllklikev.kadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiyg

IVLTYLD
.|| .| 
avledll
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 931-1037 5.7e-19 63.1 In-house 173-278 (315) alignment 
Range on Protein: 931-1037
Range on HMM: 173-278/315.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTqRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| ||||| |.|   |  |.  ..| .. |.    ... . |..||||  |||. .....   ... | . ..|||...|  | ..|  ||| ..|  |..
rtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiyd

IVLTYLD
.|| .| 
avledll
subfamily_Ptp69D_pd Subfamily Ptp69D 931-1039 7e-19 63.1 In-house 182-289 (307) alignment 
Range on Protein: 931-1039
Range on HMM: 182-289/307.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| |.|.. |.|. .   . ....| ..|...  ...  .. ||||||  ||||..| | .  ....|.|  .|.|.. |  | |..  ||  .||. ...
rkvvqyhytgWkDskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyr

IVLTYLDSF
 .| | .  
alldyssyg
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 931-1041 8.9e-19 62.7 In-house 177-289 (297) alignment 
Range on Protein: 931-1041
Range on HMM: 177-289/297.0
RSVTQFQITNWDSTGEVK--NPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGI
| | |.| ..| .  . .  . ...| ...|.  .  .. .. ..|||.  ||| .....    . . | |  .|.|...|  | ..|  ||| .||. .
rvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfv

FQIVLTYLDSFET
...|| .| | .|
yvavleallsedt
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 931-1038 1.9e-18 61.5 In-house 170-278 (281) alignment 
Range on Protein: 931-1038
Range on HMM: 170-278/281.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|.|.|.. |.|  .|  .... .|   .|......|. ....|.|||  |||.  . |  . ......|   .|| .|... | ..   |||| ||. ..
reveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvy

QIVLTYLDS
..|| .|| 
kavldaldk
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 931-1034 5.5e-18 59.9 In-house 175-277 (315) alignment 
Range on Protein: 931-1034
Range on HMM: 175-277/315.0
RSVTQFQITNWDsTGEVKNPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| | |...| |  . .| .  . || .    .  ..   ..||||||. |||.  |..  . ... ..| .|||.....  | .. . ||...||| |..
revvqlhytswp.dmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiyd

IVLT
..| 
alle
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 931-1040 5.7e-18 60.0 In-house 175-285 (288) alignment 
Range on Protein: 931-1040
Range on HMM: 175-285/288.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
. .||.| . |  .|  .. . .| ... .  .. .     |.||||. |||.  | |. . |.. ..| .|||. ...  | |..  |||..||. |..
leitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiye

IVLTYL--DSFE
..|.    |. .
vllslieedgva
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 931-1038 5.8e-18 60.1 In-house 178-290 (325) alignment 
Range on Protein: 931-1038
Range on HMM: 178-290/325.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYR---TQ--RKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
||| |||.  ||  |  | | |.. |.. .     .     .. | |.||||. |||. .| .  . ..|  .|  .|.|...|  | ..|  |.|| ||
rsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqy

QGIFQIVLTYLDS
  |.. .  .. |
iliyealveayms
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 931-1033 3.8e-17 57.6 In-house 185-288 (319) alignment 
Range on Protein: 931-1033
Range on HMM: 185-288/319.0
RSVTQFQITNWDSTGEVKNPQTILMIMEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|..||| .  |   |  . |  ......   . |........||||||  |||. .. .  . ... | |  .||.....  | |..  || . ||. |.
rkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiy

QIVL
  .|
sall
subfamily_PTPN12_pd Subfamily PTPN12 931-1036 3.9e-17 57.0 In-house 170-277 (290) alignment 
Range on Protein: 931-1036
Range on HMM: 170-277/290.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMyRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQYQG
|.|.||. |.|   |  ......| ..|.. |. ... .. .|||||  |||    .|   . .  |.| .   .|||... . | |..  ||| .||. 
rkvyqfhYtaWPDhgvPssaksllelielv.relqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyel

IFQIVLTYL
... |. ..
vykavaelv
subfamily_PTPRB_pd Subfamily PTPRB 931-1038 4e-17 57.2 In-house 179-287 (293) alignment 
Range on Protein: 931-1038
Range on HMM: 179-287/293.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQ-RKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|.|.|.. | |   |  ....|.| ..... ... ..  .. ||||||  |||.  | |  . ... ..| ..|.| .. . | ..   |||..||  | 
rkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifih

QIVLTYLDS
| ||..| .
qcvldllrk
subfamily_PTPRG_pd Subfamily PTPRG 931-1041 4.2e-17 56.6 In-house 183-292 (563) alignment 
Range on Protein: 931-1041
Range on HMM: 183-292/563.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
. |.|.. |.|  .|  . .   |. ..   .....     ||||||  |||. ....  | ... ..| ...||..||  | |..  |||  ||. ...
klvrqyhytkWPdhgvPehslpvLifvkkssaanka.eaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhd

IVLTYLDSFET
..|  . | ||
alleaiasket
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 931-1034 5.5e-17 57.2 In-house 149-253 (284) alignment 
Range on Protein: 931-1034
Range on HMM: 149-253/284.0
RSVTQFQITNWDSTGEVKNPQTILMIMEE-MYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|...|| .  |   |  . |  ......   . |........||||||  |||. .. .  . ... | |  .||.....  | |..  || . ||. |.
rkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiy

QIVLT
  .| 
salle
subfamily_PTPN6_pd Subfamily PTPN6 931-1039 5.6e-17 56.7 In-house 186-300 (306) alignment 
Range on Protein: 931-1039
Range on HMM: 186-300/306.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRG---NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGV---IDVFQVLKSQRIQKPGSVQTVQQ
|.| |.. ..|   |  |.|...|  .|.. | |..     . .||||||. .||   |    . ... ...|.   ||. .. || | |. | ||| ||
revfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqq

YQGIFQIVLTYLDSF
|. ..... .|... 
ykfvykaikkyietk
subfamily_CG7180_pd Subfamily CG7180 931-1036 6.3e-17 56.2 In-house 180-290 (296) alignment 
Range on Protein: 931-1036
Range on HMM: 180-290/296.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRG-----NTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
| |..||.| |..  .|    . |. . .. |. |..      .  .||..|| ..|| ...|.  .... . |. .|||. .|  |...|. |..|..|
RivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeY

QGIFQIVLTYL
. |....| ..
kyiYdvlleav
subfamily_PTPN23_pd Subfamily PTPN23 931-1036 1.4e-16 55.2 In-house 171-280 (288) alignment 
Range on Protein: 931-1036
Range on HMM: 171-280/288.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEM---YRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
.||.  |.|.| . |  . |.|.| ...|.   |...... .| .|||||  |||. .|.   . ... .  .|..|. ||..  | |.  .||...|..
ksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlk

GIFQIVLTYL
  ...||.. 
fsyeavleaa
subfamily_PTPN13_pd Subfamily PTPN13 931-1038 1.7e-14 48.8 In-house 166-271 (273) alignment 
Range on Protein: 931-1038
Range on HMM: 166-271/273.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRkrGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
| |.... ..|   |  .... .| .. |. | |.   .. ||||||  .||| .. .  . ..  . .  .|| ..... | |. | ||| .||  ...
revahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvyk

IVLTYLDS
..|. | |
ailevlks
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 931-1037 4.1e-14 47.2 In-house 152-265 (270) alignment 
Range on Protein: 931-1037
Range on HMM: 152-265/270.0
RSVTQFQITNWDSTGEVKN------PQTILMIMEEMYRTQRKRGN-TSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQ
| .. |. ..|   | ...      .. .| ..... |....  . . ..||||. |||. .. |  ....  .... .|| ....  | ...  ||...
rrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpe

QYQGIFQIVLTYLD
||. ... |..| .
qyeflykavveyae
subfamily_PTPN9_pd Subfamily PTPN9 931-1036 5.6e-13 43.6 In-house 173-290 (297) alignment 
Range on Protein: 931-1036
Range on HMM: 173-290/297.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQR---------KR---GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGS
|.|| ||.. |   |  .. ...| ..|.. ..|          ..    .  ||||||  .||.  |..   .... ...|..||....|  | |.  |
rkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafs

VQTVQQYQGIFQIVLTYL
.|| .||.  .. || | 
iqtpeqyefcylavleya
subfamily_PTPRN_pd Subfamily PTPRN 931-1032 2.4e-12 41.2 In-house 187-288 (297) alignment 
Range on Protein: 931-1032
Range on HMM: 187-288/297.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRGnTSIVVHCSDTVGRSAMFCAAATTINKC-KTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
|.||||    | ..|   .....|     . .. | |  ..||||||| .||. ....    .|.  |    ||.   |.  | |.|| |.| .|.. ..
rtvtqfhflswpeegvPasaksllefrrkvnksyrGrs.cpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefal

QIV
. |
tav
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 931-1033 2.8e-10 34.8 In-house 133-236 (237) alignment 
Range on Protein: 931-1033
Range on HMM: 133-236/237.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKR-GNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
| . |.|.| |   |  ..  ..| .  ..    ..    .  ..|||  |||...|    . . ..| . |.|... ..|   ..|  .|| .||  |.
rlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfih

QIVL
| .|
qtil
subfamily_PTPN1_pd Subfamily PTPN1 931-1031 4.6e-10 33.7 In-house 162-266 (290) alignment 
Range on Protein: 931-1031
Range on HMM: 162-266/290.0
RSVTQFQITNWDSTGEVKNPQTILMIMEEMYRTQR-KRGNTSIVVHCSDTVGRSAMFCAAATTIN---KCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQ
|....|  | |   |  . |.. |  . .. ..   ..     |.|||  .|||  || . | .    | .    .|. .||   | .. | .|| .| .
reilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlr

GIFQI
  .. 
fsyla
subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 931-1036 2.3e-06 21.5 In-house 188-289 (305) alignment 
Range on Protein: 931-1036
Range on HMM: 188-289/305.0
RSVTQFQITNWDSTGEvknPQTILMIMEEMYRTqRkRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
 || ..| |.|   |    |   |  .| .    |   .  ||||||  .||.    |    ..|   .  .  . ...|. | |.  |.|.  ||  | 
msvrhlqwtewpdrgv...ppckltslellsai.r.gskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfih

QIVLTYL
...| |.
rvmlnyf
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 932-1037 6.5e-13 42.8 In-house 279-386 (392) alignment 
Range on Protein: 932-1037
Range on HMM: 279-386/392.0
SVTQFQITNWDSTGEVKNP--QTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIF
.|||.|.  |   |  ...  ...| ..  .  .  .. . ||.|||    ||. .||.|   | .      .|.|| .|  | ..  .||| ..|  ..
tvtqyqfhgwpkhgsdqqsgarsllkliravkgstnskkefsilvhclsgagrtgvfctameciaqiaegdsvdifqtvkilradrmqfvqteeeyafvy

QIVLTYLD
...  || 
dvireylh
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 932-1037 2.4e-08 28.1 In-house 169-278 (287) alignment 
Range on Protein: 932-1037
Range on HMM: 169-278/287.0
SVTQFQITNWdsTGEVKNPQ---TILMIMEE--MYRTQRK-RGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQY
 | |... .|    .|  |     | ....       .|.  .   .|||..  .||| .. |  . ... .  | .|| .|.   | .. . ||.| |.
vvkqldllsw..PdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvql

QGIFQIVLTYLD
. ... . ||  
rllyealvtyyk
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 932-1037 1.9e-07 25.1 In-house 187-288 (305) alignment 
Range on Protein: 932-1037
Range on HMM: 187-288/305.0
SVTQFQITNWDSTGEvknPQTILMIMEEMYRTQRKRGntSIVVHCSDTVGRSAMFCAAATTINKCKTEGVID-VFQVLKSQRIQKPGSVQTVQQYQGIFQ
 ||..   .|   |    | . | |.| . ...  .|   ||||||  .||.         ...  .  .|.   ..|.  | |.  |.|| .||  . |
kvthyhwidwpdrgv...paadlailellekarpskg..pivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhq

IVLTYLD
..| |. 
vilnyfr
subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 932-1033 2.6e-06 21.8 In-house 159-256 (290) alignment 
Range on Protein: 932-1033
Range on HMM: 159-256/290.0
SVTQFQITNWDSTGEVKNPQTILMIMEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCK-TEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
 ||  .. .|...   ....|.| ... .     |  .| ..||| | . |||.. |      |   |.| . . .|||. | |.   ... ...  .  
tvtHsllkgWnklnvqedtktllsliqkv.....kasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvda

IVL
 ..
giv
subfamily_hpo-7_pd Subfamily hpo-7 932-1035 8e-06 19.9 In-house 123-226 (263) alignment 
Range on Protein: 932-1035
Range on HMM: 123-226/263.0
SVTQFQITNWDSTGEVKNPQTILMIMEemyrTQrkRGNTSIVVHCSDTVGRSAMFCAAATTIN-------KCKTeGVIDVFQVLKSQRIQKPGSVQTVQQ
 |.... . |  . ...... || |..        |.  |.|||||  .|||| |  | .          . .| . .|  ..|.  | .......|  |
tvkhysykgWiekndpelareilnilk....va..rnskslvvhcstGiGrsaafsvaElvyqkmirsldttst.veldylsLleelrssrkraihtPmq

YQGIFQIVLTY
    . .||..
LafsilmvLdf
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 933-1034 4.3e-24 79.9 In-house 164-264 (283) alignment 
Range on Protein: 933-1034
Range on HMM: 164-264/283.0
VTQFQITNWDSTGEVKnPQTILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIV
.. .|. .| . ||   .   |. .. .   |..  .. |||||| ..||.|.|.||...... .|| |.|||.|.|  | |... ||| .||. . ..|
lahyqvidWleygeqa.iinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv

LT
| 
le
PTPc_DSPc_SM00012 933-1032 3.1e-21 70.9 In-house 2-103 (105) alignment 
Range on Protein: 933-1032
Range on HMM: 2-103/105.0
VTQFQITNWDSTGEVKNPQTILMIMEEMYRTQRKRG-NTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQ
|.....|.|  .|  .... || ..... . ..|.. ....|||||. |||...|.|... ......| . .|.||..|. | |.||.||| .||. . .
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr

IV
..
al
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 933-994 1.7e-06 22.0 In-house 217-287 (350) alignment 
Range on Protein: 933-994
Range on HMM: 217-287/350.0
VTQFQITNWDSTGEVKNPQTILMIME--------EMYR--TQRKRGnTSIVVHCSDTVGRSAMFCAAATTIN
| |.|. ||   . . ||. || ..|         . .   . .|. ..|.||||  |||  ....    ..
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnars.spilvhCsaGvGrtGtlvtlDslls
0046846 (Phosphotyrosine protein) phosphatases II 934-1037 1.8e-12 42.8 In-house 77-174 (176) alignment 
Range on Protein: 934-1037
Range on HMM: 77-174/176.0
TQFQITNWDSTGEVKNpQTILMIMEEMYRTQRKRgnTSIVVHCSDTVGRSAMFCAAAttinKCKTEGVIDVFQVLKSQRIQKP-GSVQTVQQYQGIFQIV
 |.. ..|.  |     . .| ..|.... ...     ..||||  .||.....||      ...|  ..|...|.  | |.| |.||| .||. . . .
iqylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyefe

LTYLD
| .|.
llllk
subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 934-1036 2.1e-08 28.5 In-house 174-271 (288) alignment 
Range on Protein: 934-1036
Range on HMM: 174-271/288.0
TQFQITNWDSTGEVKNPQTILMIMEEMyrtqrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVL
 .  . .||  |  .| .. | ..| .     |  .  ||||.|  |||.. .      ..  . .  . . ..|.. | ..  ..|| .||  ....||
kilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvl

TYL
 .|
eel
subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 938-1036 1.4e-09 31.8 In-house 188-285 (302) alignment 
Range on Protein: 938-1036
Range on HMM: 188-285/302.0
ITNWDSTGEVKNPQTILMIMEEMYRTQrKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.||| ..   ..  ..   .....  .   .. ..|.     .|| ..| ..|....| ...    . ...|| | |.| .|....||  .. ..|.|.
ltnWkqkkvpvkyaeliktaakvfakk.ikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyi
subfamily_Cele-PTP-5_pd Subfamily Cele-PTP-5 951-1036 2.1e-07 23.9 In-house 223-309 (346) alignment 
Range on Protein: 951-1036
Range on HMM: 223-309/346.0
QTILMI-MEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYL
.|. .| |   . ....  |. . |      ||.  |  |  .||.       ......|. . |.||.|..  || .|. ||. |.
ktlpiikmihqflsekqvqnagvcvvslfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyi
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 953-1034 9e-17 55.9 In-house 176-257 (267) alignment 
Range on Protein: 953-1034
Range on HMM: 176-257/267.0
ILMIMEEMYRTQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLT
.  ..  . . | . ||  .||.||| ||||  |  . . ... ||||| |.|. |.  | |..| |.| ..|  | ...  
lkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 954-1039 2.1e-07 24.9 In-house 203-286 (290) alignment 
Range on Protein: 954-1039
Range on HMM: 203-286/290.0
LMIMEeMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTInKCKTEG-VIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTYLDSF
| ..  . |. ||  .  .|||||  .||.  | |  ... .. ..|  .|. .. .. |  . .|||   ||  . .|.| .  .|
lallr.tlrilrka.sGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkdf
subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 955-1035 7.4e-08 26.4 In-house 187-268 (281) alignment 
Range on Protein: 955-1035
Range on HMM: 187-268/281.0
MIMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEG-VIDVFQVLKSQRIQ-KPGSVQTVQQYQGIFQIVLTY
 .| .. |  | |  |  |.|||  ||||  . |   ...  ..   . |. |..   |.  .  ||||.|||  |....| .
evmlkilrkirar.stppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 956-1035 2.4e-10 34.8 In-house 216-294 (297) alignment 
Range on Protein: 956-1035
Range on HMM: 216-294/297.0
IMEEMYRTQRKRgNTSIVVHCSDTVGRSAMFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
.  | .|..  | |. ..||||  |||| .   . . ..| . . . ||  .|.  | |..  |||..|.. ....||  
lqleslraempr.nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkk
subfamily_CG42327_pd Subfamily CG42327 963-1035 2e-08 28.3 In-house 241-314 (319) alignment 
Range on Protein: 963-1035
Range on HMM: 241-314/319.0
TQRKRGNTSIVVHCSDTVGRSAMFCAAATTINKCKTE-GVIDVFQVLKSQRIQKPGSVQTVQQYQGIFQIVLTY
. ..  .  .|||||| |||. .  |.  .|.. ..    .|. |.. | | ..  .|.|..||. |....  |
sgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey