Gene PTPRD-32 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP087_AA protein Get Run
AqueP087_AA_789-1009 phosphatase_domain Get Run
Domains
Summary
5001000MQFSLLSTGSLVAPPVFSLSFNVSDGPPTTVSCSVNGTGISTELSRVIVNGPGSVTRVTVTNLTEAGNYQCTVSNDRVINGSTNDDSGPDAANSTSSLNILVSDAPTGLTATRLSIGLAHVRLSWSTVSGATSYEVFSKPQTLSPVSVGTTVSITFNITSGLFRGIAYTFYVASYGSASLLSGNASVMLTISDPAVTVLVATLITSTSITLTWSPPTAVVPISYNIVRDCRRVCESSKVGTSEASVSSPHTSTGIPPYSQCTFDLIGVYDITVELTTDFSAKTLSTAPTALVGDIILSSVESVSMTVSWDEVPCNGRKGPITGYYLTYTNITSNTSYTVNITGGDNRMYNLRGLIPYTNYTVSIIPYNYNMNGPARQEIQLTPESIPGVISDLRHGKNPDAINIVWNPPTIPNGIITVYEIRYRESTSTGSYTITNTTDTIYSIVGLIPNTSYTIGVRAYTSIGPGEWTDREYITAQIFVLEMFSVTKLNSTAVRAEWNLILRASHYTVYYESTSSSSRKKRQVETGMRVFPGGTTEGLIGGLDPNLNYLFSISISFTVNGVIYEGERTQPIQPADIPTSTSDAANGSSVIFIVIGAVVCILVLIVTITIIVVVNVLKKRRGSNDIDIVSKNTSTNKPEATVYYSTCRNSNNEAGYEEIGLERIEEATYSTVMKPKKPVIEEFPSNMTTEEGCQVLLKVKVKDTSKPSFNWYHNGDLVTDDYAHELRGDGSLLLVSVEEKHKGTYRFVANNDAGTVSQQVVLTVAVEGARRMPSNGTSAVKSGKNLIPVRQFGEFVANGHAKGNEGFKNQFMMLDSGESDHTGTAGLTPSNKLLNRFANIVVSRNFWKMIDDRNVTAIVMLCQEKENDLEVCYQYWPSTSSGIILGEYNITLLKENTSNRYIERKFEVKNTNTGAKQSVTQFQVTNWDSTGEVKNPQTILMIIEEMYKTQRKRGNTSIVVHCSDTVGRSAIFCAAATTINKCKTEGVIDVFQVLKSQRIQKPGSVQTVVIHVGEGQAPPSNIRPSQGVRLYLPYEDRPIPDYSMIYASQFYDQDENNDVENINDALWCQSANTSSTIGAWYYPNGTEVPLFEGPFNDLSAPSPMYSKRFSGQIALARRDGLSGYEGLYKCIIPDENGVNQTLVVGAYTDYKYNSSNGPDADPTPTPCurated phosphatase domainfn3fn3I-setY_phosphatasePfam Domainsubfamily_Sponge-PTP10_pd(1)subfamily_Sponge-PTP11_pd(2)0051299(3)0050432(4)0047943(5)SubfamilyTransmembrane region
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
fn3 Fibronectin type III domain 294-374 2.9e-12 39.8 Pfam-A 5-83 (85) alignment
fn3 Fibronectin type III domain 397-468 8.3e-14 44.7 Pfam-A 11-84 (85) alignment
Ig_3 Immunoglobulin domain 677-751 6e-07 21.6 Pfam-A 1-75 (75) alignment
Ig_2 Immunoglobulin domain 677-764 9.9e-07 20.7 Pfam-A 1-80 (80) alignment
I-set Immunoglobulin I-set domain 678-764 1.9e-13 42.0 Pfam-A 1-90 (90) alignment
0051299 (Phosphotyrosine protein) phosphatases II 785-1008 8e-51 168.6 In-house 3-272 (288) alignment
0045450 (Phosphotyrosine protein) phosphatases II 786-1008 1.5e-46 154.9 In-house 8-290 (307) alignment
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 786-843 2.9e-22 73.9 In-house 1-58 (290) alignment
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 786-844 2e-18 61.4 In-house 1-60 (287) alignment
0043336 (Phosphotyrosine protein) phosphatases II 787-1008 3.3e-44 146.8 In-house 2-263 (278) alignment
0039614 (Phosphotyrosine protein) phosphatases II 791-1008 1.2e-44 148.4 In-house 18-275 (297) alignment
0040438 (Phosphotyrosine protein) phosphatases II 792-1008 9.4e-47 155.2 In-house 5-262 (317) alignment
0050432 (Phosphotyrosine protein) phosphatases II 794-1008 3.9e-50 166.3 In-house 33-285 (308) alignment
0047943 (Phosphotyrosine protein) phosphatases II 800-1008 6.2e-48 159.0 In-house 7-258 (273) alignment
0036941 (Phosphotyrosine protein) phosphatases II 801-1008 8.2e-48 158.6 In-house 9-263 (297) alignment
0046845 (Phosphotyrosine protein) phosphatases II 807-1008 6.2e-47 155.7 In-house 2-260 (284) alignment
0045098 (Phosphotyrosine protein) phosphatases II 819-1008 2.4e-41 137.3 In-house 21-258 (278) alignment
subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 824-979 4.8e-15 50.3 In-house 22-172 (255) alignment
0040439 (Phosphotyrosine protein) phosphatases II 825-1008 1.7e-40 134.6 In-house 5-232 (249) alignment
0049772 (Phosphotyrosine protein) phosphatases II 826-999 1.3e-13 46.8 In-house 41-255 (314) alignment
0037934 (Phosphotyrosine protein) phosphatases II 827-1008 2.2e-37 124.3 In-house 6-228 (243) alignment
0042113 (Phosphotyrosine protein) phosphatases II 829-1008 7.1e-41 135.6 In-house 7-229 (245) alignment
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 838-1007 9.1e-17 55.5 In-house 96-221 (392) alignment
subfamily_Sponge-PTP4_pd Subfamily Sponge-PTP4 840-939 3.9e-08 27.2 In-house 147-242 (244) alignment
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 842-1008 1e-19 65.6 In-house 63-226 (239) alignment
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 842-1008 1.2e-19 65.5 In-house 64-227 (239) alignment
subfamily_Sponge-PTP-4_pd Subfamily Sponge-PTP-4 842-935 1.6e-07 25.7 In-house 40-129 (130) alignment
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 843-1008 1.5e-41 137.2 In-house 88-252 (283) alignment
subfamily_PTPN3_pd Subfamily PTPN3 843-1008 1.2e-30 101.4 In-house 97-261 (280) alignment
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 843-1007 4.1e-27 89.9 In-house 105-264 (315) alignment
0036282 (Phosphotyrosine protein) phosphatases II 843-1007 2.3e-26 87.9 In-house 27-155 (174) alignment
subfamily_PTPN9_pd Subfamily PTPN9 843-1007 2.8e-25 83.9 In-house 98-275 (297) alignment
subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 843-1008 3.6e-20 66.9 In-house 103-267 (301) alignment
0051082 (Phosphotyrosine protein) phosphatases II 843-1009 3.4e-17 57.9 In-house 22-140 (151) alignment
subfamily_CG42327_pd Subfamily CG42327 843-947 3.9e-12 40.5 In-house 85-191 (319) alignment
subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 843-1007 2.3e-06 21.5 In-house 95-261 (312) alignment
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 844-1009 2.4e-90 297.4 In-house 100-265 (287) alignment
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 844-1009 1.3e-86 285.1 In-house 105-270 (290) alignment
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 844-1007 7.4e-48 158.3 In-house 103-268 (305) alignment
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 844-1008 5.3e-44 145.1 In-house 99-279 (301) alignment
Y_phosphatase Protein-tyrosine phosphatase 844-1008 1.9e-41 137.4 Pfam-A 56-223 (235) alignment
Y_phosphatase Protein-tyrosine phosphatase 844-1008 1.9e-41 137.4 In-house 56-223 (235) alignment
DSPc_SM00195 844-1007 1.8e-40 134.3 In-house 83-247 (263) alignment
PTPc_SM00194 844-1007 1.8e-40 134.3 In-house 83-247 (263) alignment
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 844-1007 2.2e-39 130.4 In-house 103-265 (318) alignment
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 844-1008 5.5e-35 115.8 In-house 66-228 (250) alignment
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 844-1010 1.4e-33 111.2 In-house 98-264 (281) alignment
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 844-1007 1.3e-32 107.9 In-house 101-262 (315) alignment
subfamily_PTPRK_pd Subfamily PTPRK 844-1007 1.7e-31 104.2 In-house 100-262 (314) alignment
subfamily_PTPN12_pd Subfamily PTPN12 844-1007 1.8e-31 104.1 In-house 97-262 (290) alignment
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 844-1007 1.8e-31 103.8 In-house 100-261 (515) alignment
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 844-1007 8.2e-31 102.2 In-house 106-269 (297) alignment
subfamily_PTPN23_pd Subfamily PTPN23 844-1009 2.7e-30 100.2 In-house 97-267 (288) alignment
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 844-1007 2.1e-26 87.6 In-house 87-253 (274) alignment
subfamily_PTPN1_pd Subfamily PTPN1 844-1008 1.6e-25 84.4 In-house 85-257 (290) alignment
subfamily_PTPN13_pd Subfamily PTPN13 844-1007 2.9e-25 84.1 In-house 91-254 (273) alignment
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 844-1009 7.8e-24 78.9 In-house 94-264 (287) alignment
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 844-1009 3.2e-23 77.1 In-house 78-251 (270) alignment
subfamily_PTPN14_pd Subfamily PTPN14 844-1008 2.2e-22 74.4 In-house 107-282 (300) alignment
0051429 (Phosphotyrosine protein) phosphatases II 844-1009 2.4e-22 75.4 In-house 36-212 (272) alignment
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 844-1008 3.9e-21 70.3 In-house 59-225 (237) alignment
0041856 (Phosphotyrosine protein) phosphatases II 844-1008 1.1e-19 66.1 In-house 48-157 (182) alignment
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 844-1007 9.8e-19 62.1 In-house 108-268 (290) alignment
0046846 (Phosphotyrosine protein) phosphatases II 844-1007 2e-18 62.2 In-house 37-158 (176) alignment
0044763 (Phosphotyrosine protein) phosphatases II 844-1006 3.3e-16 54.9 In-house 38-155 (178) alignment
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 844-1009 5.6e-15 49.7 In-house 105-266 (439) alignment
subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 844-1007 2.8e-14 47.3 In-house 105-273 (302) alignment
subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 844-1008 9.8e-14 45.7 In-house 95-255 (281) alignment
subfamily_hpo-7_pd Subfamily hpo-7 844-979 1.9e-13 44.9 In-house 48-178 (263) alignment
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 844-1007 3.5e-13 44.2 In-house 96-262 (307) alignment
subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 844-1008 8e-13 43.0 In-house 96-257 (288) alignment
subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 844-1005 2.2e-11 38.3 In-house 18-186 (198) alignment
subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 844-1005 2.3e-11 38.2 In-house 19-187 (199) alignment
subfamily_egg_pd Subfamily egg 844-1010 7.3e-10 33.0 In-house 97-258 (307) alignment
subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 844-1008 2.3e-07 24.5 In-house 107-271 (302) alignment
subfamily_PTPRD_pd Subfamily PTPRD 845-1007 1.8e-43 144.1 In-house 106-266 (564) alignment
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 845-1007 1.1e-39 131.4 In-house 114-275 (298) alignment
subfamily_PTPRA_pd Subfamily PTPRA 845-1008 2.8e-34 113.5 In-house 116-281 (330) alignment
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 845-1007 1e-32 108.5 In-house 106-268 (319) alignment
subfamily_Ptp69D_pd Subfamily Ptp69D 845-1007 2.4e-31 104.0 In-house 106-271 (307) alignment
subfamily_PTPRB_pd Subfamily PTPRB 845-1009 3.2e-31 103.5 In-house 109-272 (293) alignment
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 845-1008 1.8e-30 101.0 In-house 105-265 (288) alignment
subfamily_PTPN6_pd Subfamily PTPN6 845-1008 3.4e-30 100.1 In-house 113-283 (306) alignment
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 845-1008 4.1e-29 96.7 In-house 106-274 (325) alignment
subfamily_PTPRG_pd Subfamily PTPRG 845-1007 6.5e-29 95.6 In-house 106-272 (563) alignment
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 845-1009 2.8e-27 90.9 In-house 119-278 (319) alignment
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 845-1009 4.1e-27 90.4 In-house 83-242 (284) alignment
subfamily_PTPRN_pd Subfamily PTPRN 845-1007 1.8e-26 87.5 In-house 115-277 (297) alignment
subfamily_CG7180_pd Subfamily CG7180 845-1007 1.4e-22 74.8 In-house 100-275 (296) alignment
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 845-1008 2.2e-21 71.0 In-house 87-245 (267) alignment
0049260 (Phosphotyrosine protein) phosphatases II 845-1007 4.3e-20 67.4 In-house 24-135 (152) alignment
0043147 (Phosphotyrosine protein) phosphatases II 845-1007 9.1e-19 63.3 In-house 35-146 (172) alignment
subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 845-999 8.9e-15 49.6 In-house 82-236 (290) alignment
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 845-1007 2.8e-13 44.5 In-house 90-255 (285) alignment
subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 845-1009 6.8e-12 39.6 In-house 111-276 (305) alignment
subfamily_ptpA1_pd Subfamily ptpA1 845-982 3.2e-10 34.3 In-house 104-256 (418) alignment
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 845-1007 4.1e-09 30.6 In-house 103-272 (305) alignment
subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 845-1011 1.2e-08 28.9 In-house 109-279 (310) alignment
subfamily_eak_pd Subfamily eak 845-934 3.6e-07 23.9 In-house 108-196 (332) alignment
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 845-884 6.1e-07 23.6 In-house 91-130 (297) alignment
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 845-881 1.1e-06 22.7 In-house 119-155 (350) alignment
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 845-928 3.2e-06 20.7 In-house 251-329 (440) alignment
0048179 (Phosphotyrosine protein) phosphatases II 849-1008 2.4e-11 39.1 In-house 24-131 (144) alignment
0048076 (Phosphotyrosine protein) phosphatases II 875-1008 3.1e-12 41.9 In-house 2-129 (145) alignment
Filo_glycop Filovirus glycoprotein 894-960 5.1e-06 13.3 Pfam-A 192-260 (364) alignment
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 908-975 2.8e-07 24.6 In-house 207-282 (350) alignment
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 917-1008 5.5e-11 36.5 In-house 89-180 (440) alignment
PTPc_DSPc_SM00012 919-1007 4.7e-19 63.9 In-house 2-92 (105) alignment
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 945-1008 6.5e-06 20.2 In-house 219-281 (297) alignment