Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
fn3 | Fibronectin type III domain | 110-184 | 2e-13 | 43.5 | Pfam-A | 2-79 (85) | alignment | ||
Range on Protein: 110-184
Range on HMM: 2-79/85.0
APSSLTEVNKTTTTITVSWTALD--SSDADGYVVNVTSDTDT--VQTVQVKGSSNnTITLNGLRGGTTYSITVRAYQQL
||. |. . |.|..|.||.. . ... .|| | . ..... ....|..... . ||.||. ||.|...|.|. .
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavnga
|
|||||||||
fn3 | Fibronectin type III domain | 296-362 | 4e-07 | 23.3 | Pfam-A | 2-76 (85) | alignment | ||
Range on Protein: 296-362
Range on HMM: 2-76/85.0
PPNNVRGFILNATSIKVNWTNS----SETNGYVIEYTTGGVT--RNVVSTSEE--EIVLTDLSQMSTYTISVYSY
.| |.. ..||. ..|. . .. || .|| . | . . ..... . .||.| ..|...|...
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqav
|
|||||||||
fn3 | Fibronectin type III domain | 380-466 | 3.2e-10 | 33.2 | Pfam-A | 1-82 (85) | alignment | ||
Range on Protein: 380-466
Range on HMM: 1-82/85.0
SPVTSLSVFNVSTTGIRVNWTIP-SSDNYVTYYTISYtpfCPQLSSV-NETVSvapyQSTTTYSYTLIGLYSGMNYTITVRAGNVLGES
|... ||| .|..| ....|. | . . .|.|.. | ... .. ... . ||.|.|| || |..|...|.| | ||.
saPenlsvsevtstsltlsWsppkdgggpitgYevey...rekgggeewkeft....vprtttsvtltgLkpgteYefrVqavngageg
|
|||||||||
fn3 | Fibronectin type III domain | 483-563 | 2.6e-12 | 39.9 | Pfam-A | 2-85 (85) | alignment | ||
Range on Protein: 483-563
Range on HMM: 2-85/85.0
SPSSIQVVQLNSTANRFTWNEVNcsERNGLITGYTVIISNS-----SITYNLTSTEKYIILNNLVFGTEYNISVAAVNSVGRGPFS
.|. ..| . .|| ...|.. . ...| ||||.| ... . ......|.. .|..| ||||...|.||| .| ||.|
aPenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 716-883 | 3e-57 | 189.1 | In-house | 3-170 (305) | alignment | ||
Range on Protein: 716-883
Range on HMM: 3-170/305.0
PVSVDELGTHV---ATCHSNGFDEQYEGLYTGiDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDmcQREYINASYIDGYSSSNKFIASQGPMK
....|.| ... . ...|...||. ||. .. . .| .|.|.| ||.|.||..||.||||... .|| ...||||||.|||....|.|..|||.|
iialddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdgykrkkkyivaqgPlk
KTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYSDYVVRQISVTV
.|..||||||..||...|||.|.|.|| |.||.||||. .|. .||.|.|.|..|. .|||. |......
ntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisi
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 716-881 | 4.8e-50 | 165.8 | In-house | 4-168 (564) | alignment | ||
Range on Protein: 716-881
Range on HMM: 4-168/564.0
PVSVDELGTHVATCHSN---GFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLdmCQREYINASYIDGYSSSNKFIASQGPMK
|..|.|| .||| ..| |.|.|. . .| .. ...| | ||..||. || .|..| . .. . .|||||.|||| .....||.|||..
pipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegd..egsDYINAsfidgyrkrkayIAtqgPla
KTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGrAeSDDFGPFTVTLTNEQVYSDYVVRQISV
.|. ||||..|... .|||.|.|.| .| ||..|||. . .| .||||..|. ..||..|....
etiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtleeeeeladyeirtfkl
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 716-882 | 1.2e-42 | 141.0 | In-house | 13-179 (330) | alignment | ||
Range on Protein: 716-882
Range on HMM: 13-179/330.0
PVSVDELGTHVAT---CHSNGFDEQYEGLYT-GIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDmcQREYINASYIDGYSSSNKFIASQGPM
|. |..| . .. | |... | . |. . . .||| ||. || || .|.||.. . . . .|||||.|||| .||||.|||
plpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGve..esdyinasfidGykekdkfiaaqGPk
KKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRaeSDDFGPFTVTLTNEQVYSDYVVRQISVT
..|. ||||.||. | .|||.|.||| ..||.||||. . .| .|.. .|.| || ||.. |.
eetvedfwrmiweqksativmltelkerkeekcaqywPdeG..lvtyGnirvevedetvlvdytvrkflvq
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 716-882 | 1.3e-42 | 140.9 | In-house | 6-173 (293) | alignment | ||
Range on Protein: 716-882
Range on HMM: 6-173/293.0
PVSVDELGTHVATCHS---NGFDEQYEGLY-TGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSSSNKFIASQGPM
|...... .||.. .. .| |.|| | | |. . . ...|.| ||..|| || .|. ||. . | . .||||.||.||.| ..|||.|||.
piklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalk..desgsDYinanyipgynsprefiatqGPl
KKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESdDFGPFTVTLTNEQVYSDYVVRQISVT
.|. ||||..|..| |||.|.| |. | |||.|||. . . .| .|||..|....|.|.|.....
petvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepv.lyGdikvtlvaeeeledwvirelkie
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 716-883 | 6e-39 | 128.8 | In-house | 5-170 (315) | alignment | ||
Range on Protein: 716-883
Range on HMM: 5-170/315.0
PVSVDELGTHVAT---CHSNGFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILaPNRKLDmCQREYINASYIDGYSSSNKFIASQGPMK
|. .|.| |.|| ||| ..|| . | . . . || ||. || || |. | | . | . .|.||..||||. ...||.|||
pipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvql.pllend.phsdyvnanfidGynkkrryiaaqgpnv
KTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGraeSDDFGPFTVTLTNEQVYSDYVVRQISVTV
.. |||||...|. |||.||| || |.|.|.|||. .|..|||. .|.|...| || .||..
asvkdfwrlvfeedigkivmltnlvegekrkaekywpdk...kviyGkitvtrkseevnteytvrtlsvvf
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 716-881 | 5.8e-38 | 125.7 | In-house | 4-168 (319) | alignment | ||
Range on Protein: 716-881
Range on HMM: 4-168/319.0
PVSVDELGTHVATCHSNG---FDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKldMCQREYINASYIDGYSSSNKFIASQGPMK
.. |.|| ... . .|.| ...... | .. .. .||| ||..|| || |..|.. . . .|||||.|||| .|||| |.|..
eievqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldg..vegsdyinasfidgyqerekfiatqaPle
KTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAEsdDFGPFTVTLTNEQVYSDYVVRQISV
.|. ||||..|.|. .||.|.|.| | |...|||. | ..| ..||| .|. .||..|....
ntiedfWrmvWeeessivvmltklveklkvklkkywpeenfe..eyGrlivtleeeeeledyiirklkl
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 716-809 | 4.6e-12 | 40.0 | In-house | 4-95 (95) | alignment | ||
Range on Protein: 716-809
Range on HMM: 4-95/95.0
PVSVDELGTHVATCHSNG---FDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDmcqreYINASYIDGYSSSNKFIASQG
|. | . .|| ||| ||... . .| | | ||| || || |..|. .| | |||| ..|||. | .||.||
pihvsvfhshvlemhsnsdqefdnefksismtsgapytvgsseanipknrflnifpydatrvvlttkrdsd.....yinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 717-882 | 4e-52 | 171.9 | In-house | 2-169 (290) | alignment | ||
Range on Protein: 717-882
Range on HMM: 2-169/290.0
VSVDELGTHVATCHS---NGFDEQYEGLYTGI-DKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDMCQREYINASYIDGYSSSNKFIASQGPMK
. ||..| .||. |. .|| .|.. | .| .. .| ..| |||.|| |||||||.| | . |. |||||.||.||. ....|| |||..
ipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvs
KTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGraESDDFGPFTVTLTNEQVYSDYVVRQISVT
.||||||.|||||| |||.|| .| | || ||||. .....|.|...|.||.....|. |...|.
ntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds..dtkaygefsikllneetlneyierklevk
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 717-882 | 4.6e-45 | 148.8 | In-house | 2-164 (287) | alignment | ||
Range on Protein: 717-882
Range on HMM: 2-164/287.0
VSVDELGTHVATCHSN---GFDEQYEGLYT--GIDKRCIIGYNEENTAFNRFKNITVYDDNRIILApnrkldMCQREYINASYIDGYSSSNKFIASQGPM
..|...| ||. | . || .|. | .. .. ..| ||...| |.|..|..| .. .||||..||||.....||....||
ipvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykekkafiiaesPm
KKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAesDDFGPFTVTLTNEQVYSDYVVRQISVT
.|...||.||..... |||....|| ....| ||||.... .|.....|.||.|...|..|.. |.
fntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyniellneevnagyierklevk
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 717-881 | 3.1e-43 | 142.8 | In-house | 1-168 (563) | alignment | ||
Range on Protein: 717-881
Range on HMM: 1-168/563.0
VSVDELGTHVATCHSNG---FDEQYEGLYTGIDKR---CIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDMCQrEYINASYIDGYSSSNKFIASQGP
| |.|. ||| .|..| |.|..| | . . .. . ..|| || ||. || |. |.| . .||||.||||| |..|||.|||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyidGyqkskafiatqgp
MKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNgrAESDDFGPFTVTLTNEQVYSDYVVRQISV
.|.|. ||||.||... |||.|||.| .. ||..|||. || ..| ..|||..|.| . | ||....
lkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlvi
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 717-882 | 1.3e-41 | 137.7 | In-house | 2-167 (318) | alignment | ||
Range on Protein: 717-882
Range on HMM: 2-167/318.0
VSVDELGTHVATCHSNG---FDEQYEGLYTGIDKRCI-IGYNEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSSSNKFIASQGPMK
.||..| .||. ...| ..|.|| | .. .. | | ||. ||. ||. |. | . . . .||||.||||| .....||.|.|.
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmle..geegsDyinanyidGyrrkkayiaaqaPlp
KTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNgrAESDDFGPFTVTLTNEQVYSDYVVRQISVT
.|. ||||..|. . |||.|...| .| |...|||. .| .| .|.|..| .||||.|...||
etieDfWrmvWeqnsavivmltqeeergkakvhryWPs..kgsrsygklvvelkeevelsdyvlrefkvt
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 718-882 | 8.8e-39 | 128.3 | In-house | 12-177 (306) | alignment | ||
Range on Protein: 718-882
Range on HMM: 12-177/306.0
SVDELGTHVATCHSNGFDEQYEGLYTGID---KRCIIGYNEENTAFNRFKNITVYDDNRIILApnrKLDMCQREYINASYIDG--YSSSNKFIASQGPMK
|.|| . . . .|| |..| | . | ||. ||.||| .|..|.||. . .. . .||||.||.. .|....||.|| ..
rvselekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikkevkgsdksyiatqgcle
KTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDdFGPFTVTLTNEQVYSDYVVRQISVT
.|. ||||..|||. |||.|. | .|.|| .|||. .... .| .|| ..|. .||..|..||.
ttvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladYilRelsvs
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 719-882 | 1.4e-40 | 134.3 | In-house | 6-169 (307) | alignment | ||
Range on Protein: 719-882
Range on HMM: 6-169/307.0
VDELGTHVATCHS---NGFDEQYEGLY-TGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDmcQREYINASYIDGYSSSNKFIASQGPMKKT
.|.| . . . . |. . || | . ||| . .. ..||. ||...|. .|..|..|.. . . .|||||.| || ..||||.|.|. |
iddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingke..dsdYinasfikgykekkkfiaaqdPveat
LVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGraESDDFGPFTVTLTNEQVYSDYVVRQISVT
. ||||.|.. . |||..||.| .. ||..|||. . .| |.| .|. |||. |...|.
igDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqygdilvklvseekhsdyiiReldvs
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 719-882 | 3.4e-37 | 123.1 | In-house | 3-165 (297) | alignment | ||
Range on Protein: 719-882
Range on HMM: 3-165/297.0
VDELGTHVATCHSNGFDEQYEGLYTG-IDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDmcQREYINASYIDGYSSSNKFIASQGPMKKTLVD
..|| ..| . .| ..|. . . . | ||.... ||. |. || . . . .||||...||| . ||| |||.||| |
ieelvayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdede..asdyinanfvdGykqkkafiatqGplkktvsd
FWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYSDYVVRQISVT
|||..|... . |||.| . | . || ||||... .|..|| ..|. . ....||.||.. ..
fWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleik
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 720-883 | 3.9e-80 | 263.7 | In-house | 3-166 (301) | alignment | ||
Range on Protein: 720-883
Range on HMM: 3-166/301.0
DELGTHVATCHSNGFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFW
..||||||..|||.|.|||. |..| ||.|..|..|||.|.||||||||||||||||.|...||.|||||||||||||||...||||.||||||||||||
edlgthvaakhsnkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfW
RLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYSDYVVRQISVTV
|||||||||||||||||||||||||||||||..|||..||||||||.||||| |.|.||..|..
rliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvki
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 725-881 | 1.5e-40 | 134.1 | In-house | 14-168 (288) | alignment | ||
Range on Protein: 725-881
Range on HMM: 14-168/288.0
HVATCHSNGFDEQYEGL-YTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIW
. .|| |.|. | . .| .| . .| ||..|| || .|. | . . .|||||||||. ...|.||.|||. .|. |||.|..
kksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkle..eeagaDYinasyidgekkkkkyiatqgPladtvndfWelvy
QEKPVSIVMVTNLKEGTKSKCEQYWPNGRaESDDFGPFTVTLTNEQVYSDYVVRQISV
..| |||.|.| || |.|||.|||.. . .| .||||.... |.|.|.. .
enktstivmltelveggktkCeeYWPdad.kpknyGsvtvtlveskeledfvlrklll
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 726-881 | 5.2e-39 | 128.9 | In-house | 16-162 (314) | alignment | ||
Range on Protein: 726-881
Range on HMM: 16-162/314.0
VATCHSNGFDEQYEGLYTGIDKrciiGYNEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQE
. .... || |.|| |. | | ..|| . ||...| || |..| . . . .||||..||.| ...||. |||...|. |||||...|
lkraegygfkeeyeslfegwda....akkdenreknrsgdilaydrsrvflitid..gdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvyde
KPVSIVMVTNLKEGTKSKCEQYWPNgraESDDFGPFTVTLTNEQVYSDYVVRQISV
. ||||.|.|.| .. || .|||. ... .|.. |.| . .. ...||| .|
ncasivmltelvevgrvkClkyWPe...dtevygdikvelvetellaelvvrifrv
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 729-800 | 2.9e-06 | 20.9 | In-house | 19-88 (440) | alignment | ||
Range on Protein: 729-800
Range on HMM: 19-88/440.0
CHSNGFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSS
| |.... | .|. . . | .| ||..|| .|| .|..| . . . .|||||||.| |
rrsrafedewsllpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevk..gvpdsdyinasyingies
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 730-882 | 1.4e-41 | 138.3 | In-house | 30-177 (297) | alignment | ||
Range on Protein: 730-882
Range on HMM: 30-177/297.0
HSNGFDEQYEGLYTGIDKrCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDMcQREYINASYIDGYSS-SNKFIASQGPMKKTLVDFWRLIWQEKPV
........| |. .. . |.. .|| .||.|.| ||..|..| |... |. ||||||.|||. ..||||.|||...|. ||||..|...
sktllllefeellslkpd.ysiallpenkdknrykdilpydhsrvklkpedgvdl.dsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvt
SIVMVTNLKEGTKsKCEQYWPNGRAesdDFGPFTVTLTNEQVYSDYVVRQISVT
.|||.|.|.| . ||.||||. .|.|||||........|.||...||
vivmLtklvelgr.kcaqywpeegg...tygdftvtllkvehldgytvrtlevt
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 730-882 | 3.4e-41 | 136.9 | In-house | 18-165 (278) | alignment | ||
Range on Protein: 730-882
Range on HMM: 18-165/278.0
HSNGFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKldMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVS
.. ...| |.. . |.. .|| .||.|.| || .|..| . . ||||||.|||. ..||||.|||...|. ||||..|... .
lktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllgg..dldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvtt
IVMVTNLKEGTKSKCEQYWPngrAESDDFGPFTVTLTNEQVYSDYVVRQISVT
|||.|.|.| . || |||| .| .|.|||||..|....||.||.. ||
ivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevt
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 730-881 | 1.3e-38 | 127.8 | In-house | 13-162 (281) | alignment | ||
Range on Protein: 730-881
Range on HMM: 13-162/281.0
HSNGFDEQYEGLYT-GIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDMCqrEYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPV
...|| |.||.|. |.|. ...||. ||..||. || |. ..|| . .. .||||....||.. ...||.|||. ..||.||...|..|
dnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenknt..DYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvs
SIVMVTNLKEGTKSKCEQYWPNGRAeSDDFGPFTVTLTNEQVYSDYVVRQISV
|||||. |. | || .|||.... . .| .||. |.|. . |. |....
aivmvtreieagklkChrYWPddns.elkygdvtvkstaeeekatyierkfkl
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 730-880 | 6.8e-36 | 118.7 | In-house | 17-165 (315) | alignment | ||
Range on Protein: 730-880
Range on HMM: 17-165/315.0
HSNGFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPnrKLDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVS
|. | |.. | | .. ...| ||.||| .| .|..| | ...||||||| .. . . .|||||| | .. ||||...|||. .
htalfseefhdlpdPdiyrqrvaretinfkknryknilPldsarvklev..iddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvtt
IVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYSDYVVRQIS
|||||...|| | || ||||. .|.| .|| . |.| . . .| |.|..
ivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklv
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 730-850 | 7.8e-25 | 82.1 | In-house | 18-144 (392) | alignment | ||
Range on Protein: 730-850
Range on HMM: 18-144/392.0
HSNGFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILApnRKLDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVS
|| | |.. | . .. .| | ||.||| || .|..| |. ...|.|||||... . . .|||||| .| ||||...||.. .
hsalffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkle..viddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvtt
IVMVTNLKEGTKS----KCEQY----WPN
|.|||.|||| | . |. ||.
iamvtklkegdkgddartvaqfhftewPd
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 731-882 | 1.1e-38 | 128.2 | In-house | 26-177 (298) | alignment | ||
Range on Protein: 731-882
Range on HMM: 26-177/298.0
SNGFDEQYEGLYTGID----KRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEK
|...... | .. . . .. ..|| ||. .| .| |..| . . . .|||||....|. .| |||.|.|...|..||||....|.
ltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLeked..adeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteed
PVSIVMVTNLKEGTKSKCEQYWPNGRaeSDDFGPFTVTLTNEQVYSDYVVRQISVT
.|||.|||.| | |...|||. . .. .| .||.| ......|..||.. |.
igtiVmltnleeldktkyhkywPdeg..ketygeitvsllskeefadlivrklkvs
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 732-882 | 3.8e-43 | 143.3 | In-house | 18-164 (317) | alignment | ||
Range on Protein: 732-882
Range on HMM: 18-164/317.0
NGFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKldMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIV
... |..| |.. . . ... .|| .||...| ||..|..| | . ||||||.||.. ..|||| |||...|. ||||..|... .||
talleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtviv
MVTNLKEGTKSKCEQYWPNgrAESDDFGPFTVTLTNEQVYSDYVVRQISVT
|.|.|.| . ||.||||. |. .|.|||||..|........|.. |.
mLteleelgrekcaqYwpl..getltygdftvtllseeelagitlrtleve
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 732-883 | 4.5e-40 | 133.7 | In-house | 27-187 (307) | alignment | ||
Range on Protein: 732-883
Range on HMM: 27-187/307.0
NGFDEQYEGLYTGIDK---RCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLdMCQREYINASYI--------DGYSSSNKFIASQGPMKKTLVDFWR
.|. ...| |. .. . |.. .|| .||.|.| ||..|..| . . . ||||||. ||| ...|||| |||...|. ||||
tgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwr
LIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGrAESDDFGPFTVTLTNEQVYSDYVVRQISVTV
..|... |||.|.|.| .. || ||||. |. .|.|||||..|.....|.||.. ||
mlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseehldgytvrtlevtd
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 732-868 | 6e-19 | 62.7 | In-house | 27-159 (310) | alignment | ||
Range on Protein: 732-868
Range on HMM: 27-159/310.0
NGFDEQYEGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKldmCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIV
.|. || | . | ... ||. .. . |. |. | .. .|| | |. . || ||||...|..||||.|.||. ||.
eglvkqyrkldakqdssltyeaykkymhknrysdvvcldtsrvklkidks...ryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesil
MVTNLKEGTKSKCEQYWPNGrAESDDFGPFTVTLTNE
.. . | . || ||| .. .| || .|
llckvgeegrpkcvgywpsl.gvtetygcirvtnlse
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 733-883 | 3.6e-44 | 146.7 | In-house | 24-171 (288) | alignment | ||
Range on Protein: 733-883
Range on HMM: 24-171/288.0
GFDEQYEGLYTGI-DKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKldMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIV
|. |..| |. . | . ... .|| ||...| ||..|..| . . . |||||||||| ...|||| |||...|. ||||..|... ||
glleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIv
MVTNLKEGTKSKCEQYWPNgrAESDDFGPFTVTLTNEQVYSDYVVRQISVTV
|.|.| | . ||.||||. .| .|..||||..|.|..||.||.. ||
mltklvelgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtn
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 733-881 | 1.8e-12 | 41.9 | In-house | 20-158 (288) | alignment | ||
Range on Protein: 733-881
Range on HMM: 20-158/288.0
GFDEQYEGLYTGIDKRCIIGYNeENTAFNRFKNITVYDDNRIILApnrklDMCQrEYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVM
| . .|. . .. | . .|.. .|..|. | |. | | .. ||.| . ...| .| |.. |. .|... .. |||
glkkeyrdspneasidiidsfi.anptrdryenlprcditrvkls.....ddpd.fyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivm
VTNLKEGTKSKCEQYWPNGRAESDDFGPFtVTLTNEQVysDYVVRQISV
...| | | | ..|.| |. .| . | . .. . . . ..|
lcellekGkeksaeyfPsklGekarigrl.ctvvkkkr..adidklvkv
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 734-883 | 4.2e-43 | 143.2 | In-house | 44-190 (308) | alignment | ||
Range on Protein: 734-883
Range on HMM: 44-190/308.0
FDEQYEGLYTGID-KRCIIGYNEENTAFNRFKNITVYDDNRIILapnrklDmCQREYINASYIDGY--SSSNKFIASQGPMKKTLVDFWRLIWQEKPVSI
..|..| |. . . ... .|| .||.|.| || .|..| | ||||||.||| ...|||| |||...|. ||||..|... |
leeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl......d.egsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvI
VMVTNLKEGTKSKCEQYWPNGRA-ESDDFGPFTVTLTNEQVYSDYVVRQISVTV
||.|.| | . ||.||||. .| .|.|||||..|.|..||.||.. .|
vmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltn
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 734-883 | 2.5e-42 | 140.6 | In-house | 2-157 (284) | alignment | ||
Range on Protein: 734-883
Range on HMM: 2-157/284.0
FDEQYEGLYTGIDK---RCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKlDMCQREYINASYIDGY-----SSSNKFIASQGPMKKTLVDFWRLIWQE
..|..| |. | . ... .|| ||.|.| .||..|..| . . |. .||||||.||| ...|||| |||...|. ||||..|..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldg.dledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
KPVSIVMVTNLKEGTKSKCEQYWPNGrAESDDFGPFTVTLTNEQVYSDYVVRQISVTV
. |||.|.| | . ||.||||. |. .|.|||||..|.|..||.|| ...|
nvrvIVmltelvengrekcaqYwple.gevltygdftvtllseevkddytvrtleltn
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 737-882 | 7.3e-33 | 108.7 | In-house | 20-163 (280) | alignment | ||
Range on Protein: 737-882
Range on HMM: 20-163/280.0
QYEGLYTGI-DKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKlDMCQREYINASyIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTN
|.| || . . . || . ||...|. ||. |..| ... | .|.| |.. . .|..||.|||..|| |||...|..| |||.|.
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklkeset.dyinanyvnme.ipstglvnryiatqGPlaktatdfWqmvweqksslivmltt
LKEGTKSKCEQYWPNgRAESDDFGPFTVTLTNEQVYSDYVVRQISVT
| | . || ||||. .. ..| |.|....|. . ||.|.. ..
lverGrvkChqyWPe.tedeleygefsvkcekedetksyvlrelvlk
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 739-883 | 1.9e-38 | 127.9 | In-house | 15-143 (278) | alignment | ||
Range on Protein: 739-883
Range on HMM: 15-143/278.0
EGLYTGIDKRCIIGYNEENTAFNRFKNITVYDDNRIIlapnrkldmcqrEYINASYIDGYssSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKE
. | .|| .. . ..| ..||.|.| || .|.. .|||||||||| ..|||| |||...|. ||||..|... .|||.|.|.|
fllllgipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelve
GTKSKCEQYWPNgrAESDDFGPFTVTLTNEQVYSDYVVRQISVTV
... ||.||||. .| .|.|||||..|.|..||..| . ||
lgrekcaqywpe..ggsltygdftvtllseevlddytlrtllvtn
|
|||||||||
DSPc_SM00195 | 741-883 | 5.5e-40 | 132.7 | In-house | 9-151 (263) | alignment | |||
Range on Protein: 741-883
Range on HMM: 9-151/263.0
LYTG-IDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLdmCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEG
| . .|.. . ..|.. ||.||| .||..|..| .. | . .||||.||.|.....|.|| |||...|. ||||..|.|| |||.|. .|
leestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeen
TKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYS-DYVVRQISVTV
| ||..|||. .. .|| ..|.|.... .. ....|....|
gkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltk
|
|||||||||
PTPc_SM00194 | 741-883 | 5.5e-40 | 132.7 | In-house | 9-151 (263) | alignment | |||
Range on Protein: 741-883
Range on HMM: 9-151/263.0
LYTG-IDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLdmCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEG
| . .|.. . ..|.. ||.||| .||..|..| .. | . .||||.||.|.....|.|| |||...|. ||||..|.|| |||.|. .|
leestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeen
TKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYS-DYVVRQISVTV
| ||..|||. .. .|| ..|.|.... .. ....|....|
gkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 744-878 | 4.2e-24 | 79.8 | In-house | 43-175 (297) | alignment | ||
Range on Protein: 744-878
Range on HMM: 43-175/297.0
GIDKRCIIGYNEENTAFNRFKNITVYDDNRIILApnRKLDMCQREYINASYID-GYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKS
.. . .. .|.| || |.. ||..|. | .. . . .||||| | . .||.|||. .|. |||...|.. | ||..|.|.| .
aepstkevakaeknvkknrskavlpydhsrvklk..eeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvk
KCEQYWPNGRAESddFGPFTVTLTNEQVYS-DYVVRQ
.|..|||. .| .. . | | | ... ||.||
qckrywpdeGsev..yhiyevhlvsehiwcddylvrs
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 744-854 | 9.9e-09 | 29.0 | In-house | 41-144 (302) | alignment | ||
Range on Protein: 744-854
Range on HMM: 41-144/302.0
GIDKrCIIgyNEENTAFNRFKNITVYDDNRIilapnrKLDMCQREYINASYIDGYSSSNKFIASQGPMKKTL---VDFWRLIWQEKPVSIVMVTNLKEGT
..| | . .|...|. ... ..|.|.. ||.... .|.||| .. . ... | .| | ... .|||...||| ||.|.. .| .
dlek.Cka..fkknlkknqsedvpildsnlv......kleaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelk
KsKCEQYWPNGRAE
| ....|. .
k.tlselfpkksgd
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 745-883 | 1.3e-37 | 124.2 | In-house | 21-154 (283) | alignment | ||
Range on Protein: 745-883
Range on HMM: 21-154/283.0
IDKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKldmcqrEYINASYID---GYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTK
|. . | ..|| .||...| ..| .|. | .. . .||||..| | ..|.|..|.|...| ||||.....|| ..|||.|.|.|. .
pdldadiasadenkrknrnqeivpadqwrvelksesr......dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlr
SKCEQYWPNgrAESDDFGPFTVTLTNEQVYSDYVVRQISVTV
|| ||||. | |.|.||||| .| ...... . |
ikCsqyWPk..rGsedyGeftvtlrkettsnsfiikelllrv
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 746-883 | 1.9e-41 | 137.7 | In-house | 27-159 (273) | alignment | ||
Range on Protein: 746-883
Range on HMM: 27-159/273.0
DKRCIIGYNEENTAFNRFKNITVYDDNRIILapnrklDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCE
. . ... .|| .||.|.| ||..|..| .. ||||||.||| ...|||| |||...|. ||||..|... |||.|.| | . ||.
lltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekca
QYWPNGRAE-SDDFGPFTVTLTNEQVYSDYVVRQISVTV
||||. | | .|.|||||..|....||.||.. .|
qYwpleggelsltygkftvtllseetkddytvrtleltn
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 746-876 | 1.4e-28 | 94.7 | In-house | 38-169 (300) | alignment | ||
Range on Protein: 746-876
Range on HMM: 38-169/300.0
DKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLdmcQREYINASYIDGYSSS--NKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSK
| . . ..||. ||||.. |.|||. |.|... . .||||| | .. ..|..|||...|. |||...|... |||.|. .|. | |
dallstaklpenaeknrfkdvlPyednrvelsptken...stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkek
CEQYWPNG--RAESDDFGPFTVTLTNEQVYSDYVV
. .|.|. .... .|| | || . . ..
sfkyfPkleskkktvefgkfkvttkfsedsdsvit
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 746-877 | 2.4e-20 | 67.7 | In-house | 22-144 (267) | alignment | ||
Range on Protein: 746-877
Range on HMM: 22-144/267.0
DKRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLdmcqreYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGtksKCE
.. . |.| ..||. . |||.|.|| . . ||||||..|| |.||. |.|.|.| ||. .| ..| ||..|. .. .
sstisqsiaeknqernrlddnlpyddtrvilrtkeee......yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftd...nir
QYWPNGRAESDDFGPFTVTLTNEQVYSDYVVR
..|| ... . .|| . |. || .
lfwPPkmgqakkyqdltvehslekeendyqii
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 747-883 | 1.2e-42 | 141.6 | In-house | 29-161 (297) | alignment | ||
Range on Protein: 747-883
Range on HMM: 29-161/297.0
KRCIIGYNEENTAFNRFKNITVYDDNRIILapnrklDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQ
. .. ..|| ||.|.| ||..|..| | ||||||.|||. ..|||| |||...|. ||||..|... .|||.|.| | . ||.|
gslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaq
YWPNGRAESDDFGPFTVTLTNEQV--YSDYVVRQISVTV
|||. || .|.|||||....| ..||..|.. ||
ywpleegesltygdftvtllsvevvllddytlrtlevtd
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 747-882 | 9.8e-27 | 88.9 | In-house | 27-158 (273) | alignment | ||
Range on Protein: 747-882
Range on HMM: 27-158/273.0
KRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKldmcqreYINASYIDGYSSSNKF--IASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKC
..| .| ..||.. ||..|. ||. |..| . |||||.| ... ||.|||. .| |||...|. | |.|||. ||. | ||
dtcevgkkkenkdknryrnvlPydetrvklgdegg.......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkc
EQYWPNGRAESDDFGP-FTVTLTNEQVYSDYVVRQISVT
..|||. . .. ..|.| . | ....|||.. |.
hrywPesknkklkvsnrlevellkvqkldgfvvralavk
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 747-849 | 1.1e-17 | 60.2 | In-house | 36-164 (314) | alignment | ||
Range on Protein: 747-849
Range on HMM: 36-164/314.0
KRCIIGYNEENTAFNRFKNITVYDdNRIILapnRKLDMCQREYINASYIDGYsssNKFIASQGPMKKTLVDF----------WRLI--WQEKPVSIVM--
. . ... ..| ||...| .| || || .|.. ||||||.||. .||||.|||.. |.||| ||.. .. .. |||
ltilvadlflnrdknryldilpad.nrvil...pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsr
-------------------VTNLKEGTKSKCEQYWP
..| ... ......
devladelsrLdaAlgKtpllildgngneptaadle
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 747-834 | 3.4e-11 | 37.3 | In-house | 27-117 (347) | alignment | ||
Range on Protein: 747-834
Range on HMM: 27-117/347.0
KRCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDM---CQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVT
.. | . . || |. . |. |..|.|.. |||||.| .|...| .| |. .|. |||... | .| .
skftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtif
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 748-882 | 8.7e-27 | 88.5 | In-house | 33-162 (296) | alignment | ||
Range on Protein: 748-882
Range on HMM: 33-162/296.0
RCIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDmcQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKsKCEQY
| |...|| || .. || ||..| . . .||||.|.|.. ...| ..|.|.|. .||||...|. ..|..|. . .| .. .|
dCagglrkenreknrdvkvvPyDynRvvLekldGee..ksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsy
WPNGRaeSDDFGPFTVTLTNEQVYSDYVVRQISVT
||| ..|.. | ...|. |.. . |.. .|
wpnks..keqygeifveiveekqyanlkirtfklt
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 748-876 | 1.4e-23 | 77.9 | In-house | 48-168 (290) | alignment | ||
Range on Protein: 748-876
Range on HMM: 48-168/290.0
RCIIGYNEENTaFNRFKNITVYDDNRIILApnrklDMCQREYINASYIDGYSssNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQY
| |. | | . ||.|... | |.|| | . .|. | |..| || .||..|.| .|.||.. ||| |||. .| | |.|||||
rkifdkntefk.knrykdvvcndktrvilk.....dGydGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqy
WPNGRAESDDFGPFTVTLTNEQVYSDYVV
.|. | || .||. ..|. . ..
ypekeGevltfGeitvlcseeddkdanii
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 748-880 | 7e-22 | 72.5 | In-house | 37-162 (439) | alignment | ||
Range on Protein: 748-880
Range on HMM: 37-162/439.0
RCIIGY--NEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKskce
.|| .| . . ||.|... .| |..| . . |||| ||.|| . .||.||| |.| |||||....| | |||.||| | |
aciaslaaqeydqtknrykdvgafdhtrvtlqeip..gvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk....
qYWPNGraESDDFGPFTVTLTNEQVYSDYVVRQIS
||| . .| .| . .||.| .
.ywpsd..aevcygdiavrvdrnielpnyvirgfk
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 749-882 | 5.2e-37 | 123.2 | In-house | 3-132 (249) | alignment | ||
Range on Protein: 749-882
Range on HMM: 3-132/249.0
CIIGYNEENTAFNRFKNITVYDDNRIILAPNRKLDMCQreYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYW
. ... .|| ||...| || .|..| . ..| . |||||||||| ....||| |||...|. ||||..|... .|||.|.|.| . ||.|||
ysvallpenkdknrypdilpydhsrvklsilpglflsd..yinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqyw
PNgrAESDDFGPFTVTLTNEQVYSDYVVRQISVT
|. .| .| |||||....|..||.||.. .|
pl..ggsleygdftvtllsvevkddytvrtlelt
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 750-882 | 2.3e-35 | 116.7 | In-house | 36-166 (515) | alignment | ||
Range on Protein: 750-882
Range on HMM: 36-166/515.0
IIGYNEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWP
. .| | ||.||| || .|..| | . .|.||||| .. . . .|||||| | .. |||||..||.. |.|||.|||| |.|| .|||
tvaqeeinfkknryknilPydsvrvklevin..dnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWP
NGRAESDDFGPFTVTLTNEQVYSDYVVRQISVT
. ..| || . | | . .. . |.. |.
dkpgdsvkfGsikvelvsleactggikrkltvl
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 750-882 | 2.6e-32 | 107.7 | In-house | 3-124 (243) | alignment | ||
Range on Protein: 750-882
Range on HMM: 3-124/243.0
IIGYNEENTAFNRFKNITVYDDNRIILapnrklDMcqREYINASYIDGYsssNKFIASQGPMKKTLVD----FWRLIWQEKPVSIVMVTNLKEGTKSKCE
|. .|| ||...| ||..|..| . ||||..|... ...||.|||...|. | |||..|... .|||.|.|.| .. ||.
siallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekca
QYWPngraESDDFGPFTVTLTNEQVYSDYVVRQISVT
|||| .. .|.|||||..|....||.|| ....
qywp....gevtygdftvtllseehlddytvrtllle
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 750-877 | 3.1e-18 | 60.4 | In-house | 30-156 (281) | alignment | ||
Range on Protein: 750-877
Range on HMM: 30-156/281.0
IIGYNEENTAFNRFKNITVYDDNRIILAPNrKLDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWP
. . | ||. || . | |. | . . .|| | || .| .||| |.| ||||.||||. .|||. .. | . || .|.|
tvfnqpvnnkknrylnipcldisrvqlkvk.mpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfp
NGRAESDDFGPFTVTLTNEQVYSDYVVR
.| ..|. . | |
rnahcclqfdklsvsyedstvnkslvtt
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 751-882 | 2.1e-35 | 117.0 | In-house | 34-164 (290) | alignment | ||
Range on Protein: 751-882
Range on HMM: 34-164/290.0
IGYNEENTAFNRFKNITVYDDNRIILAPNRKLDmcQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPN
| .|||.. ||.|.| || .|. | ... . . .||||..| | ... ..||.|||. ||| ||||.||. . .||. .. | | |||.|||.
agekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpe
GRAESDDFGPFTVTLTNEQVYS-DYVVRQISVT
|. ||.|.|||..|. . |...|.. |.
egeeelefgefevtleeekavdddflirtLkve
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 751-881 | 6.1e-33 | 109.3 | In-house | 42-169 (325) | alignment | ||
Range on Protein: 751-881
Range on HMM: 42-169/325.0
IGYNEENTAFNRFKNITVYDDNRIILApnRKLDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLI--WQekpVSIVMVTNLKEGTKSKCEQYW
. || | |||||. .| .|..| | | . .||||||. . . |.|.| |. .|. |.|||. |. |.|.|.| .. | .| .||
vamkpenkaknrfknvvaldksrvvle..tkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr...csvvvvlneldlgkdrcavyw
PNGRAESDDFGPFTVTLTNEQVYSDYVVRQISV
|. ..| ||.. | | . .|||| |.. |
pkemgksktfGglevklrtieeisdyvhrvldv
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 752-882 | 7.3e-37 | 121.9 | In-house | 4-129 (250) | alignment | ||
Range on Protein: 752-882
Range on HMM: 4-129/250.0
GYNEENTAFNRFKNITVYDDNRIILAPNRKLDMCqrEYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSkCEQYWPNG
. . .| ||. .| .| |..| ... . . .|||||...||. .. |||.|||...|..||||....|| .|||.||||| | ..||||
akkpqnkeknryadiialdssrvvLekekgdkes..dyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve
RaeSDDFGPFTVTLTNEQVYSDYVVRQISVT
. .. .| ||.| ......||..|.. ..
k..aekyGdvtvsllskeefadytkrklkls
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 752-879 | 5.3e-20 | 66.5 | In-house | 42-162 (418) | alignment | ||
Range on Protein: 752-879
Range on HMM: 42-162/418.0
GYNEENTAFNRFKNITVYDDNRIILapNRKLDMCQREYINASYIDGYsSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNG
| .. ||. ||. || . |. | .. | .|||| |||| ..||..|||. .|. ||||..|... |||.. | . ||..|||.
gdkkhntsknrytnilpvnhtrvql..kkiqdkegsdyinanyidga.ypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeq
RAeSDDfgpFTVTLTNEQVYSDYVVRQI
.. |.. ..|. | | .
ig.geq...fsiygngnevfgtysvelv
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 753-882 | 4.4e-35 | 116.7 | In-house | 5-130 (245) | alignment | ||
Range on Protein: 753-882
Range on HMM: 5-130/245.0
YNEENTAFNRFKNITVYDDNRIILAPNRKLDMCQreYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNgr
. .|| .||...| ||..|..| | . ||||||.||| ..||||.|||...|. ||||..|... .|||.|.. | . ||.||||.
llpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..
AESDDFGPFTVTLTNEQVYSDYVVRQISVT
|| .| |||||..|....||.||...||
gesltygdftvtllseehlddytvrtlevt
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 753-869 | 1.3e-08 | 28.8 | In-house | 92-199 (244) | alignment | ||
Range on Protein: 753-869
Range on HMM: 92-199/244.0
YNEENTAFNRFKNITVYDDNRIILApnrKLDMCqREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWqEKPVSIVMVTnlkeGTKSKCEQYWPNGR
.| .|. || .| ||. |. | | |||||.. . ..| .| |. | .|||... |. | ...| |. . ..|||.
fnpnnswknregaglpfdfnrvpls...kgsmg.ntyinasfvgclgrtaeyiltqhpladtsmdfwkmml.erhvnvlvvl....gsveeedeywpdse
AESDDFGPFTVTLTNEQ
|||||. .
plewyeeditvtltdrd
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 754-882 | 1.3e-30 | 101.2 | In-house | 40-163 (288) | alignment | ||
Range on Protein: 754-882
Range on HMM: 40-163/288.0
NEENTAFNRFKNITVYDDNRIILApnrkldMCQREYINASYIDGYSS-SNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGR
. .. ||...| || ||. | . .|||||.. . |. . .|||.|.|...|| |||......| |||... .| | |...|||. .
aklyseknrsrdilPyDhnRvklr......gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedk
AESDDFGPFTVTLTNEQVYSDYVVRQISVT
|. ||...||| ... . .| |.....
getvkfgdlsvtlksvretethvervlkle
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 754-882 | 4.9e-29 | 96.4 | In-house | 48-169 (297) | alignment | ||
Range on Protein: 754-882
Range on HMM: 48-169/297.0
NEENTAFNRFKNITVYDDNRIILAPNRklDMCQREYINASYIDGYSSsnKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKsKCEQYWPNGRA
. | .|.||| || .|..|| | . .|.|||.. |. ..|..| ||| |. |||.....|.. |||.....|..| || .||..
kkvnfeksRYkniLPydssRvkLaivn..ddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkgv
ESddFGPFTVTLTNEQVYSDYVVRQISVT
. || .|.|. . . .. |...||
tt..fGdvsvvllsvsereGfikrelevt
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 754-881 | 5.6e-25 | 82.6 | In-house | 29-153 (290) | alignment | ||
Range on Protein: 754-881
Range on HMM: 29-153/290.0
NEENTAFNRFKNITVYDDNRIILAPNRKldmcqrEYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRA
..|| . ||..... || ||.| . . .||||| .. ..| .|||. .| ||...|..| ..||. .. | . || ||||.|
lpenrnlnryrdvspydhsrikleradn......dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgee
-ESDDFG--PFTVTLTNEQVYSDYVVRQISV
.. . ..|.| .|...| |.||.. .
ekellledtklkvkliseerksyytvrllel
|
|||||||||
subfamily_egg_pd | Subfamily egg | 754-872 | 2.8e-21 | 70.5 | In-house | 37-151 (307) | alignment | ||
Range on Protein: 754-872
Range on HMM: 37-151/307.0
NEENTAFNRFKNITVYDDNRIILapNRKLDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGtkSKCEQYWPNGRA
...| | | . | |. | . . . ..| | ...| |.|| .| |.| | ||||...||. |||.| || .|| |||. .
sdnnlekarskrvhckdssrvkl..elrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaes
ESDDFGPFTVTLTNEQVYS
.| . | .. ..| .|.|
dslvtvpGslrienlkvds
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 754-867 | 3.7e-18 | 60.5 | In-house | 26-140 (285) | alignment | ||
Range on Protein: 754-867
Range on HMM: 26-140/285.0
NEENTAFNRFKNITVYDDNRIILAPNRKLDMCQREYINASYIDGYS-SSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGR
| ||.. .. | | | | | .|.|| ||.. . .|..|||. .|| |||..|.||| ..|. | || || |.|.
nctytayeanpdlnryadvrcieetrvvlknhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypekl
AESDDFGPFTVTLTN
| || . .|||.
gevvkfgkyeitlte
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 756-882 | 2.9e-31 | 103.5 | In-house | 2-124 (237) | alignment | ||
Range on Protein: 756-882
Range on HMM: 2-124/237.0
ENTAFNRFKNITVYDDNRIILAPNRKLdmcqREYINASYIDGYSSS-NKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRaE
|| . ||. ||..|| .|..| . .||||.|..|. . .|.||.|||.. . |||...|||| |||.| | || . || .|||. .
enkiknrygnivaydhsrvvlkgagsg....sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstd.q
SDDFGPFTVTLTNEQVYSDYVVRQISVT
.| .||.|. .. .||| || . ..
paaygvltvslkkkeefsdytvrsllls
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 756-881 | 4.6e-31 | 103.3 | In-house | 60-175 (319) | alignment | ||
Range on Protein: 756-881
Range on HMM: 60-175/319.0
ENTAFNRFKNITVYDDNRIILAPNRKLDMcqREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTnlkegtKSKCEQYWPNGRAES
.| ||. || .| |.. | . .. .|||||...|| . .|.||.|||.. || ||||.||. . .||..| | || ||||. .
qnkdknriinilafdknvvklerliGeef..sdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik
DDFGPFTVTLTNEQvySDYVVRQISV
.. . |.. .| ..||||.| .
eerfkvkvdsveet..aeyvvrdiel
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 756-881 | 8.1e-31 | 102.6 | In-house | 24-139 (284) | alignment | ||
Range on Protein: 756-881
Range on HMM: 24-139/284.0
ENTAFNRFKNITVYDDNRIILAPNRKLDmcQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTnlkegtKSKCEQYWPNGRAES
.| ||. .| .| |.. | . . .|||||.| || . .|.||.|||.. || ||||.||. . .||..| | || ||||. .
qnkdknrighilafdknvvklerliGee..fsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik
DDFGPFTVTLTNEQvySDYVVRQISV
.. . |.. .| ..||||.| .
eerfkvkvdsvees..eeyvvrdiel
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 756-882 | 9.8e-29 | 95.2 | In-house | 19-146 (270) | alignment | ||
Range on Protein: 756-882
Range on HMM: 19-146/270.0
ENTAFNRFKNITVYDDNRIILAPNRKldMCQREYINASYIDGYSSS-NKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAE
....||...| |..|.. .. . .|||| |. |.... .|.||..||.. || .|||.||.|| .|||.|.|.| ..|||.|||. . |
rgkklnRyadiLPsPatRvrleelee..dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepke
--SDDFGPFTVTLTNEQVYSDYVVRQISVT
. .| .|. ..|. . |..... ..
kvkledgkikvlalseekeegyiltrlrle
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 756-854 | 1.8e-20 | 68.0 | In-house | 46-156 (350) | alignment | ||
Range on Protein: 756-854
Range on HMM: 46-156/350.0
ENTAFNRFKNITVYDDNRIILA-----P-NRKLDMCQREYINASYIDGY------SSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSK
| | ||.||| |. .|..| . .| . .||||.|. .. |.|| |.|...|. ||...| . | |...|.. | |
elfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek
CEQYWPNGRAE
|..||..| .
cyrYWqegsyd
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 756-866 | 9.1e-20 | 65.9 | In-house | 40-148 (307) | alignment | ||
Range on Protein: 756-866
Range on HMM: 40-148/307.0
ENTAFNRFKNITVYDDNRIILapnrKLDMCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAES
|| ||.... . | .||.. |.| .|| | |. .|||..|||...| .|| .. ||| |..|. .. | .| ||||||| . .
antdknryqdvkcqdkgrivv....kfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqk
DDFGPFTVTL--T
|| . |. .
lvfgeapntisva
|
|||||||||
subfamily_eak_pd | Subfamily eak | 756-866 | 2.8e-07 | 24.3 | In-house | 51-157 (332) | alignment | ||
Range on Protein: 756-866
Range on HMM: 51-157/332.0
ENTAFNrFKNITVYDDNRIILAPNRKldmCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAES
|. | .| || . . |.. .. . ||||| .. .|.| . . .. . ||... ..| .||.. . | | ..|.|. |
eavnrn.vvkivpydrylvrltssql...nrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktree
DDFGPFTVTLT
.|| . |.
lkfGildverk
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 757-879 | 2.6e-28 | 93.8 | In-house | 8-126 (239) | alignment | ||
Range on Protein: 757-879
Range on HMM: 8-126/239.0
NTAFNRFKNITVYDDNRIILApnRKLDMCQREYINASYIDGYSSSNK-FIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAes
| | ||. || || .|..| . . . .||||||. | | | .||.|| .. . ||||..|||. . |||.| | || | || ||||. .
nkaknryanivtydhsrvvle..klsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts..
dDFGPFTVTLTNEQVYSDYVVRQI
. . ||| . .|..||..| .
.kycnlrvtlrktevfadyiirtf
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 757-879 | 2.8e-28 | 93.7 | In-house | 7-125 (239) | alignment | ||
Range on Protein: 757-879
Range on HMM: 7-125/239.0
NTAFNRFKNITVYDDNRIILApnRKLDMCQREYINASYIDGYSSSNK-FIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAes
| | ||. || || .|..| . . . .||||||. | | | .||.|| .. . ||||..|||. . |||.| | || | || ||||. .
nkaknryanivtydhsrvvle..klsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdsts..
dDFGPFTVTLTNEQVYSDYVVRQI
. . ||| . .|..||..| .
.kycnlrvtlrktevfadyiirtf
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 757-881 | 3.7e-26 | 86.6 | In-house | 38-159 (287) | alignment | ||
Range on Protein: 757-881
Range on HMM: 38-159/287.0
NTAFNRFKNITVYDDNRIILAPNRKLDMcqrEYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGrAESD
.. ||. .. .||.|..|. . .| .|||| |. .| ..|||.|||. |. ||||...... |....| | .. || .|||.
avkknryadvlPiddtrvllsaegelGs...dyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPm
DFGPFTVTLTNEQV-YSDYVVRQISV
| ..|.| . .. .| || . .
rvGGysvvlldydikePeygvralrl
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 757-851 | 1.8e-17 | 58.9 | In-house | 1-74 (182) | alignment | ||
Range on Protein: 757-851
Range on HMM: 1-74/182.0
NTAFNRFKNITVYDDNRiilapnrkldmcQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTnlkegtkskCEQYWPNG
| ||...| || .| ||||....|. ...||| |||...|. ||.|...... .||..| .|.|||.
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpel
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 757-854 | 4.7e-17 | 56.7 | In-house | 48-140 (305) | alignment | ||
Range on Protein: 757-854
Range on HMM: 48-140/305.0
NTAFNRFKNITVYDDNRIILAPNrkldmCQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAE
.. ||.|.. |.||. | . ||| | |. . ...|| .| |..|| ||| . .|.| .| |. ||.| || .|.. .
eagknrykdvgcldnnrvklegp.....wpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkd
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 757-855 | 2.4e-14 | 47.7 | In-house | 55-149 (305) | alignment | ||
Range on Protein: 757-855
Range on HMM: 55-149/305.0
NTAFNRFKNITVYDDNRIILAPNRkldmcQREYINASYIDGYS-SSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAES
. . ||.... . | . . |. .|| | |. ..||..|||. .|. .|| .. |.| |||. . | | || |||| . |
aitknryqdvpcqdqsavkldkps.....psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgek
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 757-871 | 1.1e-11 | 38.7 | In-house | 48-171 (349) | alignment | ||
Range on Protein: 757-871
Range on HMM: 48-171/349.0
NTAFNRFKNITVYDDNRIILAPNRK-----------LDMCQ-REYINASYID--GYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKS
| ||.|.| |. |..| | | .. .|||| |. .| .|.|| | |. |. ||...| .. .. ... || .
lfaknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelsle
KCEQYWPNGRaesddFGPFTVTLTNEQVY
||..|| .. . .|| | | |
kcdiywqels.....ysnitvklqnssly
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 757-844 | 3.5e-10 | 33.9 | In-house | 34-118 (332) | alignment | ||
Range on Protein: 757-844
Range on HMM: 34-118/332.0
NTAFNRFKNITVYDDNRIILAPNRKLDmcqrEYINASYIDGYSSSNKFIASQGPMK-KTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKC
| .|| . ..| .|. |||. | .. |||..|||| . .| .| |.. .| |||.. . || |... .. | | |.
nmdmnriphlycfdhsrvelapqdgkd....dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrka
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 758-882 | 2.3e-37 | 124.0 | Pfam-A | 2-124 (235) | alignment | ||
Range on Protein: 758-882
Range on HMM: 2-124/235.0
TAFNRFKNITVYDDNRIILapnrkL------DmcqreYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNG
||.|.|..||..|. | | ||||.|..||....||||.|||.|.|. ||||..|||| .|||.|.|.| . ||.||||.
kkknRykdilpydktrvkl.....kgsegpsd.....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpee
RAESDDFGPFTVTLT-NEQ-VYSDYVVRQISVT
. || .| ..|.|. .|. ..|..|.....
eeesltygdikvelkekekedekeytlrklelk
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 758-882 | 2.3e-37 | 124.0 | In-house | 2-124 (235) | alignment | ||
Range on Protein: 758-882
Range on HMM: 2-124/235.0
TAFNRFKNITVYDDNRIILapnrkL------DmcqreYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNG
||.|.|..||..|. | | ||||.|..||....||||.|||.|.|. ||||..|||| .|||.|.|.| . ||.||||.
kkknRykdilpydktrvkl.....kgsegpsd.....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpee
RAESDDFGPFTVTLT-NEQ-VYSDYVVRQISVT
. || .| ..|.|. .|. ..|..|.....
eeesltygdikvelkekekedekeytlrklelk
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 759-882 | 3.9e-31 | 103.1 | In-house | 30-155 (274) | alignment | ||
Range on Protein: 759-882
Range on HMM: 30-155/274.0
AFNRFKNITVYDDNRIILAPNRKLDmCQREYINASYIDGYSSSN-KFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAE--S
||.|.| . |..| .. | . .|||| || ||. . ..| |||. .|. ||||.|.||. |||.|.||| ..||..|.|. . |
tknryktilPnensrvllesessed.edssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeis
DDFGPFTVTLTNEQVYSDYVVRQISVT
. .| . .. .. || ||....
erygdveikvekiverndysvrklvlk
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 760-866 | 4.6e-23 | 76.5 | In-house | 36-140 (297) | alignment | ||
Range on Protein: 760-866
Range on HMM: 36-140/297.0
FNRFKNITVYDDNRIILapnrKLDMCQREYINASYIDG--YSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDD
||...| .||.|. | . . .|.|||| |. . |.| .|||...|. |||.|.... ||||..|.|. ..|| |||. |
knryrdilatddtrvkl....lrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlk
FGPFTVTLT
| . |
agdvvvefl
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 760-849 | 1e-09 | 32.6 | In-house | 46-129 (312) | alignment | ||
Range on Protein: 760-849
Range on HMM: 46-129/312.0
FNRFKNITVYDDNRIILAPNRKLdmcqreYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWP
.||. || ..| |. || . .. || | .. . ..|...|||...| . ||.| .||.... . | . || .|
lnrypniqcwdrgrftlagdenf......yihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyis
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 766-882 | 4.3e-10 | 34.2 | In-house | 27-151 (290) | alignment | ||
Range on Protein: 766-882
Range on HMM: 27-151/290.0
ITVYDDNRIILAPNRKLdmCQREYINASYIDgYSSSNKFIASQGPMKKT-------LVDFWRLIWQEKPVSIVMVTNLKEGTKS----KCEQYWPNGRAE
... ..|..| | . .|| |... ... ..|..| | .|. . .|| .. ||| ..||. . .| .. |..| |. |
vpLveatrvvLkgygkr..fnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvge
SDDFGPFTVTLTNEQVYSDYVVRQISVT
. |. .|| .. | .|.. |.
elkfkgltvkCkskekeddvetRelvvk
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 774-833 | 7.5e-06 | 19.7 | In-house | 56-114 (303) | alignment | ||
Range on Protein: 774-833
Range on HMM: 56-114/303.0
IILAPNRKLDMCQREYINASYIDgYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMV
.| |. ... || |||.. ||.| | .| |. .| |||..| ..| ....
vicldhskvklsdssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlll
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 781-851 | 3.7e-09 | 32.0 | In-house | 12-73 (178) | alignment | ||
Range on Protein: 781-851
Range on HMM: 12-73/178.0
KLDMCQREYINASYIDGYsssnKFIASQGPmkktlVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNG
... .|||||.|... ...|..| .|...|..... .||..|. .|. . || .||| .
leglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpee
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 782-877 | 4.2e-18 | 60.1 | In-house | 51-149 (319) | alignment | ||
Range on Protein: 782-877
Range on HMM: 51-149/319.0
LDMCQREYINASYIDGYSS-SNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNG--RAESDDFGPFTVTLTNEQVYSDYVVR
| . ||..|||. || . | .||.| ..... ||||..|. . || .|.| | .| .|.| . . .| . ||| . .| |..
gdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryais
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 785-875 | 2e-14 | 48.0 | In-house | 73-163 (301) | alignment | ||
Range on Protein: 785-875
Range on HMM: 73-163/301.0
CQREYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYSDYV
.| | | .|. ...|||.|||.|.| ||| .. | . |||... | ...|||.| | .|. | | |.....|... .
GkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkk
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 787-841 | 4.7e-12 | 41.5 | In-house | 5-55 (172) | alignment | ||
Range on Protein: 787-841
Range on HMM: 5-55/172.0
REYINASYIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLkegtK
. ||||||.|.| ..||| |||. || ||||...... ||..|.|
sdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel....l
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 788-882 | 7.3e-19 | 63.9 | In-house | 5-111 (272) | alignment | ||
Range on Protein: 788-882
Range on HMM: 5-111/272.0
EYINASYIDGYSS---SNKFIASQGPMKKTLVDFWRLiWQEKPVSIVMVTNLKEGTKSKCEQYWP----------NGRAESDDFGPFTVTLTNEQVYSDY
||||....|| . .....|.||.. | ||||| .... .||..... | . ||..||| . |.. .| ..|||. |....||
gyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldy
VVRQISVT
..| . .|
ilrelllt
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 788-853 | 1.5e-14 | 49.6 | In-house | 3-63 (174) | alignment | ||
Range on Protein: 788-853
Range on HMM: 3-63/174.0
EYINASYIDGYSSSNKFIASQGPMKktlvdFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRA
|||||..|.. ....||.|||.. ||....... ..||....|| . || .||| |
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpelre
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 788-850 | 2.8e-12 | 42.2 | In-house | 13-71 (176) | alignment | ||
Range on Protein: 788-850
Range on HMM: 13-71/176.0
EYINASYIDGYsssnKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPN
||||..|.|. ..|| |||. .|| ||........ .|..|...| . || .|||
dyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 788-850 | 2.1e-09 | 32.7 | In-house | 4-55 (151) | alignment | ||
Range on Protein: 788-850
Range on HMM: 4-55/151.0
EYINASYIDGYsssnkFIASQGPMKktlvDFWRLIWQEKPVSIVMVTNLKEGTksKCEQYWPN
|||.||..|. ...|.||. ||..|..... .||......| .| .|.|.
dyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpe
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 794-865 | 1.1e-11 | 40.2 | In-house | 1-72 (152) | alignment | ||
Range on Protein: 794-865
Range on HMM: 1-72/152.0
YIDGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTL
.|||| ...||| |||. || ||||.... . |||.|.| | .| |||||. . .|.|. . .
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsq
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 796-865 | 2.5e-13 | 44.1 | In-house | 230-295 (440) | alignment | ||
Range on Protein: 796-865
Range on HMM: 230-295/440.0
DGYSSSNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTkskCEQYWPNgRAESDDFGPFTVTL
.||| | |||.| |. |..|||||. . . .|.|. .|.. | | ||| . | ||||||
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlndkt...csiywpv.ntrsvtfgpftvgh
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 801-881 | 1.2e-10 | 35.8 | In-house | 4-84 (199) | alignment | ||
Range on Protein: 801-881
Range on HMM: 4-84/199.0
SNKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYSDYVVRQISV
..||.| |...|. |||...|. |||| . . .. ||| . . .| ..|| . .||.. . .
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitalil
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 802-881 | 1.5e-10 | 35.6 | In-house | 4-83 (198) | alignment | ||
Range on Protein: 802-881
Range on HMM: 4-83/198.0
NKFIASQGPMKKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNEQVYSDYVVRQISV
..||.| |...|| |||...|. |||| . . .. ||| . . .| ..|| . .||.. . .
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitalil
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 812-882 | 5.8e-08 | 27.0 | In-house | 44-112 (263) | alignment | ||
Range on Protein: 812-882
Range on HMM: 44-112/263.0
KKTLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNEQVysDYVVRQISVT
.|. |.. | | |. .||... .| . ||..|.| . | . .|. |. | | ... . ..
vqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlell
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 814-882 | 1.2e-08 | 29.4 | In-house | 40-106 (255) | alignment | ||
Range on Protein: 814-882
Range on HMM: 40-106/255.0
TLVDFWRLIWQEKPVSIVMVTNLKEGTKSKCEQYWPNGRAESDDFGPFTVTLTNeqVYSDYVVRQISVT
|. |.. | | |. .||.....| .. ||..|.| . | . .|| |. .| |.| . .|
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk..ssadvvlrtleit
|