Gene PTPRD-55 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP112_AA protein Get Run
AqueP112_AA_1-99 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 1-98 4.1e-66 217.7 In-house 188-286 (301) alignment 
Range on Protein: 1-98
Range on HMM: 188-286/301.0
WDVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL-VFIGIY
|||.|.||||||.||.|||||||||||||||||||||||||.|||||||||.|||||||||.||||||||||||||||||.|||||||||||  .. ||
wdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiy
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 2-91 3.1e-18 60.7 In-house 176-264 (315) alignment 
Range on Protein: 2-91
Range on HMM: 176-264/315.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGgGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
.|.|...| ||. |. .   .....|  |   ...   |.||||||. | ..| .....  |.| .|| ..||... . .|. . ..| .
evvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqv
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 2-93 9.1e-14 46.2 In-house 176-266 (288) alignment 
Range on Protein: 2-93
Range on HMM: 176-266/288.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
.. |.| . || .|. .  . .|.... |   .|.   |||.||||. |  .|.. ..  .... ..| ..||. . . .|....  | || 
eitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlk
subfamily_PTPN13_pd Subfamily PTPN13 2-91 1.3e-12 42.5 In-house 167-254 (273) alignment 
Range on Protein: 2-91
Range on HMM: 167-254/273.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkiGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
.| ... ..||  |. ...  .||..  | . |.    ||||||||  .  ||.. .. ..|.  . .  .|| .. . .|. . | | |
evahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqt
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 2-93 3.1e-12 41.2 In-house 171-263 (281) alignment 
Range on Protein: 2-93
Range on HMM: 171-263/281.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTLV
.| |.. | ||  |.  ... .|.  ..| . ..|    |.|.|||  |  .|.| ..  ......||   .|| .| . .|...   | |.|
eveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvv
0051082 (Phosphotyrosine protein) phosphatases II 2-93 2.9e-10 35.4 In-house 59-140 (151) alignment 
Range on Protein: 2-93
Range on HMM: 59-140/151.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHrqqkIGGGPIVVHCSDTVSHSGVYCSVSIALEQckaegvVDVFQVTKAIRRSKPGAVTTLV
.|......|||. |.   . .||.... ...     ..||..||||  .. .|. . . . |..      |..... . .|.. ||.|..  
evlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnq
subfamily_ptpA1_pd Subfamily ptpA1 2-65 2.4e-06 21.5 In-house 187-255 (418) alignment 
Range on Protein: 2-65
Range on HMM: 187-255/418.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIG-----GGPIVVHCSDTVSHSGVYCSVSIALEQ
|. |.|   ||   |    . . |..  .  ||..|        ||.||||  | ..| .|.  | ...
ditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkk
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 3-92 1.3e-37 124.6 In-house 180-269 (305) alignment 
Range on Protein: 3-92
Range on HMM: 180-269/305.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
|.|.|.|||| .|..... ..|..|..| ..|.|  | |..||||..|. .||...|.||||..|.|.|||||.|.|..|......|.||
vlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtl
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 3-93 3e-33 110.0 In-house 180-270 (290) alignment 
Range on Protein: 3-93
Range on HMM: 180-270/290.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
|.|.|.| |. .| | .| |.|.||  ... | | | ..|||||||||. |.|.|.. .....|| |||.||||| |  |  ||| |.| .
vtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvq
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 3-96 7e-30 99.0 In-house 175-269 (287) alignment 
Range on Protein: 3-96
Range on HMM: 175-269/287.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL-VFIG
| |.|.|.|.  | | ||.|.| ||.. .. |.| | ..|||||||||  |...|.. .....|| |||.||||| |  |  |||.| |   ...
vkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykf
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 3-92 8.8e-25 82.5 In-house 187-276 (298) alignment 
Range on Protein: 3-92
Range on HMM: 187-276/298.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |...| ||  |. .. ..||.....|   ||. |  |..|.||. |  || .. ..  ||. |.| ||||||| |..|...||||.| 
vrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqte
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 3-92 3.5e-24 80.4 In-house 139-228 (250) alignment 
Range on Protein: 3-92
Range on HMM: 139-228/250.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |.. . ||  |. .. ..||.....|   ||..| .|..|.||  |. || .. ..  ||. | | |||||.| |..|. .|.||..|
vrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesl
subfamily_PTPRD_pd Subfamily PTPRD 3-91 5.3e-24 79.8 In-house 179-266 (564) alignment 
Range on Protein: 3-91
Range on HMM: 179-266/564.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||. |.||  |.  .....|..|..| . . . . ||||||||  |  .|... ... ||. |.|..||..|. ||.|. ..  | |
VrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqt
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 3-91 1.6e-23 78.3 In-house 177-265 (318) alignment 
Range on Protein: 3-91
Range on HMM: 177-265/318.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| |...|.||  |.  .. ..|... .| . ||| | ||||||||  |   ||.. |.| ||. |||..|||||. | .|. ..  | |
vrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqt
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 3-91 2.2e-23 77.8 In-house 180-268 (319) alignment 
Range on Protein: 3-91
Range on HMM: 180-268/319.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| .|| |.|| ... .. ...|... .. . ..|   ||||||||. |   | .. ....||. | |||.|||.. . .|  ..  | .
vkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqr
0050432 (Phosphotyrosine protein) phosphatases II 3-93 2.6e-21 71.7 In-house 199-286 (308) alignment 
Range on Protein: 3-93
Range on HMM: 199-286/308.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQqkiGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
| .|. |.|| .|.  .|. .|. .. | ...   .|||||||||. |. .|... . ..||| ..|| ||||.. | .|. .||.|.|. 
vthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpe
0036941 (Phosphotyrosine protein) phosphatases II 3-94 5.5e-21 70.6 In-house 170-265 (297) alignment 
Range on Protein: 3-94
Range on HMM: 170-265/297.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCK---AEGVVDVFQVTKAIRRSKPGAVTTLVF
| .|..|.|| .|.   |...|. |. | ...... .|||..||||. |. ||... . ..|.| .    || ||.... | .|. .||||.|| .
vthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleq
0046845 (Phosphotyrosine protein) phosphatases II 3-93 7.8e-21 70.1 In-house 167-261 (284) alignment 
Range on Protein: 3-93
Range on HMM: 167-261/284.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQK-IGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEG---VVDVFQVTKAIRRSKPGAVTTLV
|..|..|.|| .|.  .|. .|. ...| . ...  ||||||||||. |. .|... . ..||| ..||   .|||... | .|. .||.|.|| 
vthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtle
0051299 (Phosphotyrosine protein) phosphatases II 3-93 1.1e-20 69.7 In-house 184-273 (288) alignment 
Range on Protein: 3-93
Range on HMM: 184-273/288.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
|..|..|.|| .|.   |. .|. . .|.. ..  ||||.|||||. |. .|... . ..||| ..||.|||... | .|. .||.|.|. 
vthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpe
subfamily_PTPRA_pd Subfamily PTPRA 3-93 1.5e-20 68.4 In-house 193-282 (330) alignment 
Range on Protein: 3-93
Range on HMM: 193-282/330.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGgPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
| ||  | ||  |.  ||. .|...  | . .|. .| |||||||  |  .| .. ..  ||. |||..||||.. | .|  .|  | |. 
vrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtde
0047943 (Phosphotyrosine protein) phosphatases II 3-94 1.8e-20 69.0 In-house 168-260 (273) alignment 
Range on Protein: 3-94
Range on HMM: 168-260/273.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF
|..|..|.|| .|.   .  .|. |..| . .... ..||.|||||. |. .|... . ..|.| ..|| |||... | .|. .||.|.|. .
vthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeq
Y_phosphatase Protein-tyrosine phosphatase 3-92 3.1e-20 68.0 Pfam-A 135-223 (235) alignment 
Range on Protein: 3-92
Range on HMM: 135-223/235.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |...|.||  |. ..|. .|..|..| ... .   ||.|||||. |. .|......|.|||..||. |||.|. | .|...||.|..|
vkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsl
Y_phosphatase Protein-tyrosine phosphatase 3-92 3.1e-20 68.0 In-house 135-223 (235) alignment 
Range on Protein: 3-92
Range on HMM: 135-223/235.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |...|.||  |. ..|. .|..|..| ... .   ||.|||||. |. .|......|.|||..||. |||.|. | .|...||.|..|
vkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsl
DSPc_SM00195 3-92 4.4e-20 67.5 In-house 160-248 (263) alignment 
Range on Protein: 3-92
Range on HMM: 160-248/263.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |.|...||  |.  ... ||...  | ......  ||||||||. |. .|......|.|.....|  ||.|.. |..| ..||.|.||
vtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtl
PTPc_SM00194 3-92 4.4e-20 67.5 In-house 160-248 (263) alignment 
Range on Protein: 3-92
Range on HMM: 160-248/263.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |.|...||  |.  ... ||...  | ......  ||||||||. |. .|......|.|.....|  ||.|.. |..| ..||.|.||
vtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtl
PTPc_DSPc_SM00012 3-92 2.1e-19 65.0 In-house 2-93 (105) alignment 
Range on Protein: 3-92
Range on HMM: 2-93/105.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIG-GGPIVVHCSDTVSHSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTL
| ....|.||  |. .|.  .|.....| . ..|.. ..|.|||||. |. .|... ..|.|.|...| . ||.||. |..|...||.|.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqte
0040438 (Phosphotyrosine protein) phosphatases II 3-95 2.6e-19 65.1 In-house 174-268 (317) alignment 
Range on Protein: 3-95
Range on HMM: 174-268/317.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkiG-GGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF---I
| .|. |.|| .|.   |...|. .. | . ..  . |||..||||. |. .|... . ..|||.. || |||... | .|. .||||.|. .   .
vthfhytgWpdhgvppspdllldfleavreale..dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrfl
0040439 (Phosphotyrosine protein) phosphatases II 3-95 2.7e-19 65.2 In-house 142-235 (249) alignment 
Range on Protein: 3-95
Range on HMM: 142-235/249.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVFI
| ..|.|||| .|.   . ..|. |. | . ....  |||..||||. |. .|...   ..||| . |. ||.... | .|. .||||... ..
vlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqy
0045450 (Phosphotyrosine protein) phosphatases II 3-95 2.8e-19 65.4 In-house 197-293 (307) alignment 
Range on Protein: 3-95
Range on HMM: 197-293/307.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLVFI
|..|. |.|| .|.   . ..|. |. | . ...  .|||..||||. |. .|...   ..|.| ..||.   ||.... | .|. .||||... ..
vthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqy
0039614 (Phosphotyrosine protein) phosphatases II 3-94 4.6e-19 64.4 In-house 185-277 (297) alignment 
Range on Protein: 3-94
Range on HMM: 185-277/297.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF
| .||.|.|| .|.   ....|.... | .....  .|||..||||. |. .|...   ..|||.. || |||... | .|. .||||.|. .
vthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsq
subfamily_PTPRK_pd Subfamily PTPRK 3-91 8e-19 62.6 In-house 175-262 (314) alignment 
Range on Protein: 3-91
Range on HMM: 175-262/314.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKiGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||| . ||. ..  . ...|...  | . |.. . |.||||||     .|... ..| |.  . |||||||.. |..| .|.  | |
vrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmvet
0043336 (Phosphotyrosine protein) phosphatases II 3-94 2.6e-18 61.9 In-house 175-265 (278) alignment 
Range on Protein: 3-94
Range on HMM: 175-265/278.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF
| ... ..|| .|.   . ..|. . .|.....   .||..||||. |. .|... . ..||| . || ||.... | .|. .||||.|. .
vthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsq
subfamily_Ptp69D_pd Subfamily Ptp69D 3-92 3.9e-18 60.6 In-house 184-272 (307) alignment 
Range on Protein: 3-92
Range on HMM: 184-272/307.0
VIQFQVTDWPtDGIVRE-PRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
|.|.. | |. | .| | .|..|..|. | . ...   .|||||||  |..||.. .... |.|.|||  ||.|...| .|. ..  |. |
vvqyhytgWk.DskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsl
subfamily_CG7180_pd Subfamily CG7180 3-89 1.4e-17 58.3 In-house 182-273 (296) alignment 
Range on Protein: 3-89
Range on HMM: 182-273/296.0
VIQFQVTDWPT-DGIVREPRTVLQVIDDVIHRQQKI----GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAV
| .||.| |.  | .     ......  |   ..|.      ||.||..|| .| ||||... ..||. . |. ||||.  | .|||.|. |
vklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLv
0042113 (Phosphotyrosine protein) phosphatases II 3-95 1.6e-17 59.2 In-house 140-232 (245) alignment 
Range on Protein: 3-95
Range on HMM: 140-232/245.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVFI
||... ..|| .|.   ....|.... | . ... ..||..||||. |. .|... . ..||| ..|. |..... | .|. .||||.|. ..
vihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqy
subfamily_PTPRG_pd Subfamily PTPRG 3-91 2.8e-17 57.1 In-house 185-272 (563) alignment 
Range on Protein: 3-91
Range on HMM: 185-272/563.0
VIQFQVTDWPTDGIVREPRTVLQVIDDViHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
|.|.. |.||  |    .  ||. .     . .|   ||||||||  |...|.|. ..  |.| ..| .|.||.. | ||  ..  |.|
vrqyhytkWPdhgvPehslpvLifvkks.saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqt
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 3-91 9.1e-17 56.1 In-house 179-269 (297) alignment 
Range on Protein: 3-91
Range on HMM: 179-269/297.0
VIQFQVTDWPTDGIVR--EPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| |.| ..||.. . |  . ...|..|..| .  ..   ||..|||.  |   ||....   . . | |  ||.|.. | .|...|  | |
vkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqt
0045098 (Phosphotyrosine protein) phosphatases II 3-95 5.2e-16 54.3 In-house 156-261 (278) alignment 
Range on Protein: 3-95
Range on HMM: 156-261/278.0
VIQFQVTDWPTDGIVREP--RTVLQVIDDVIHRQQK------------IGGGPIVVHCSDTVSHSGVYCSVSIALEQCkaEGVVDVFQVTKAIRRSKPG-
| ... . ||  |.  .|  . .|.... . .....             .|||..||||  |. .|... . . ||..  ||.||.... | .|. .|| 
vthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpgl

AVTTLVFI
||..| ..
avqnleqy
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 3-91 6e-16 52.6 In-house 174-261 (515) alignment 
Range on Protein: 3-91
Range on HMM: 174-261/515.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGgGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||. |.||  |. .. ...|..| .|   ....   |...|||  |   ||..|.   . . |   .||||.. . ||. .|  | |
vtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqt
subfamily_PTPN6_pd Subfamily PTPN6 3-91 1.8e-15 51.8 In-house 188-282 (306) alignment 
Range on Protein: 3-91
Range on HMM: 188-282/306.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIG---GGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTT
|.|.. ..||  |. ..| .||. ..|| ..|...     ||||||||. .   | .  . | |.. . .|.   .|. .. | .|. . | | |
vfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqt
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 3-91 1.8e-15 51.6 In-house 175-262 (315) alignment 
Range on Protein: 3-91
Range on HMM: 175-262/315.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRqQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||| |.||  |. ..  ..|..| .|    ..    ...||||  |  .|| .|.   ..| | . .||||.. | .|. .|  | |
vtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqt
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 3-93 2e-15 51.9 In-house 187-278 (319) alignment 
Range on Protein: 3-93
Range on HMM: 187-278/319.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGG-GPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
. ||    ||  |    |  ...... | | ..|  .  .||||||  |  .|||  . . |.. | |  |||... . .|. ..  |  ||
itqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlv
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 3-92 2.1e-15 51.7 In-house 180-274 (325) alignment 
Range on Protein: 3-92
Range on HMM: 180-274/325.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-----GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |||.  |.  |  . | |.. ... | . ....     . .||.||||. |  .||. |.  ||..   |  ||.|.. | .|. .|  | | 
vkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetv
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 3-93 2.4e-15 51.8 In-house 151-242 (284) alignment 
Range on Protein: 3-93
Range on HMM: 151-242/284.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGG-GPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
. ||    ||  |    |  ...... | | ..|  .  .||||||  |  .|||  . . |.. | |  |||... . .|. ..  |  ||
irqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlv
0037934 (Phosphotyrosine protein) phosphatases II 3-94 7.7e-15 50.6 In-house 135-230 (243) alignment 
Range on Protein: 3-94
Range on HMM: 135-230/243.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQK-------IGGGPIVVHCSDTVSHSGVYCSVSIALEQCkaeGvVDVFQVTKAIRRSKPG-AVTTLVF
||... . ||  |.  .|  .|. .|.|.  ...        .|||..||||  |. .|...   . |...   | ||.... | .|. .|| ||.|. .
vihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsq
subfamily_PTPRB_pd Subfamily PTPRB 3-92 2.5e-14 48.0 In-house 181-271 (293) alignment 
Range on Protein: 3-92
Range on HMM: 181-271/293.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQ-QKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |.. | ||  |.  ...|.|. .  | ... ..   .|||||||  |  .|.. ..   |.. . | .||.| .  ..|...   | | 
vrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqte
subfamily_PTPN12_pd Subfamily PTPN12 3-91 7.7e-14 46.3 In-house 172-262 (290) alignment 
Range on Protein: 3-91
Range on HMM: 172-262/290.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTT
| ||. |.||  |. . . ..|..|..| ..|.     |.|||||  |   |. ... .. |. ||| .   .|||..   .|. .. .| |
vyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqt
0036282 (Phosphotyrosine protein) phosphatases II 3-95 3.4e-13 45.1 In-house 69-159 (174) alignment 
Range on Protein: 3-95
Range on HMM: 69-159/174.0
VIQFQVTDWPTDGIVREPRtVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKaEGVVDVFQVTKAIRRSKPGAVTTLVFI
.||.. . || .|    .  .|.... | . ... .|||..||||  |. .|. .   . | . . |..||.... ...|. .||.|.|  ..
giqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQy
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 3-93 3.5e-13 44.1 In-house 154-251 (270) alignment 
Range on Protein: 3-93
Range on HMM: 154-251/270.0
VIQFQVTDWPTDGIVREPR------TVLQVIDDV-IHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
.. |. ..|| .|..||.        .|... .|  .....  ..|..||||. |  .|.   . ||..  . .. ||| .. ...|. ..  | . .
lvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpe
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 3-91 1.7e-12 42.0 In-house 138-225 (239) alignment 
Range on Protein: 3-91
Range on HMM: 138-225/239.0
VIQFQVTDWPTDGIVREPRTVLQVIdDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| |...| ||  |. .   .|| .    | ..   |  | |.|||  | ..| .  .   | |.| .  ||.|.  ||||  .|  | |
vyqyhftvwpdkgvpqyatavlglr.rkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqt
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 3-91 1.8e-12 42.0 In-house 139-226 (239) alignment 
Range on Protein: 3-91
Range on HMM: 139-226/239.0
VIQFQVTDWPTDGIVREPRTVLQVIdDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| |...| ||  |. .   .|| .    | ..   |  | |.|||  | ..| .  .   | |.| .  ||.|.  ||||  .|  | |
vyqyhftvwpdkgvpqyatavlglr.rkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqt
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 3-93 1.9e-12 41.4 In-house 176-266 (439) alignment 
Range on Protein: 3-93
Range on HMM: 176-266/439.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
|.||. . ||   .  .   ||. .  .   ..|   ||.|||||  | ..|   .. ||||| |.|  ||.  . | .|. .   | .|.
vlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalc
subfamily_PTPN23_pd Subfamily PTPN23 3-85 2.8e-12 41.0 In-house 173-259 (288) alignment 
Range on Protein: 3-85
Range on HMM: 173-259/288.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIH---RQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSK
|   |.| ||  |.   | |.||..| | .    .|.    |.|||||  |  .||.. |  |...  | .|..|. || . .|. .
vshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqR
0051429 (Phosphotyrosine protein) phosphatases II 3-94 3.3e-12 42.1 In-house 122-213 (272) alignment 
Range on Protein: 3-94
Range on HMM: 122-213/272.0
VIQFQVTDWPTDGIVREPrtVLQVIDDVIHrqqkigGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVD--------VFQVTKAIRRSKPGAVTTLVF
| ... ||||..|. .|.  .|.... . .      |||..||||  .. .|... . . |..  .| .||        .... . .|.  |||| |  .
vmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeq
0043147 (Phosphotyrosine protein) phosphatases II 3-99 3.5e-12 41.9 In-house 65-154 (172) alignment 
Range on Protein: 3-99
Range on HMM: 65-154/172.0
VIQFQVTDWPTDGIVrEPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALeqckaEGVvDVFQVTKAIRRSKPGAVTTLVFIGIYL
.||.. . ||  |    .. .|.... . .....  |||..||||  |. .|. .   . |     .|. ..... . .|. .||||..  ..   .
giqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.....lgl.sleeavalvrekRpgavqnpsqyrfly
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 3-91 4.6e-12 40.0 In-house 134-221 (392) alignment 
Range on Protein: 3-91
Range on HMM: 134-221/392.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||..|.|| ... .   ..|..| .|     .    |...|||  | ..||  |.   . ..|   .||||..   ||| .|  | |
vaqfhftewPdkdvpkhtssllkfikevkadfGqy.thpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqt
subfamily_PTPN9_pd Subfamily PTPN9 3-84 2e-11 38.5 In-house 175-268 (297) alignment 
Range on Protein: 3-84
Range on HMM: 175-268/297.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQ------------KIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRS
|. ||.. ||  |. ..  ..|.|.. | ..|             .. | |||||||  .  .| .... |.|.. . .|.|||... | .|  
vthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtq
0041856 (Phosphotyrosine protein) phosphatases II 3-92 3.1e-11 38.7 In-house 79-157 (182) alignment 
Range on Protein: 3-92
Range on HMM: 79-157/182.0
VIQFQVTDWPTDGIVRePRTVLQVIDDVIHrqqkiGGGPIVVHCSDTVSHSGVYCSVSIALEQckaeGvVDVFQVTKAIRRSKPGAVTTL
.||.. . || .|.   ....|. |..|..      |||..||||  |. .|...   . ...    | |..... | .|. .||.|.|.
giqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitp
subfamily_PTPN3_pd Subfamily PTPN3 3-86 4.1e-11 37.3 In-house 173-255 (280) alignment 
Range on Protein: 3-86
Range on HMM: 173-255/280.0
VIQFQVTDWPTDGIVREPRTVLQVIDDViHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKP
..|.| ..||  |.  ..  .|.... | .....    |.|||||  .  .||.  . .||    |.  | . .. . .|  . 
ilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqra
0048076 (Phosphotyrosine protein) phosphatases II 3-94 8.6e-10 34.0 In-house 47-131 (145) alignment 
Range on Protein: 3-94
Range on HMM: 47-131/145.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKigGGPIVVHCSDTVSHSGVYCsvsiALEQCKAEGvVDVFQVTKAIRRSKPGAVTTLVF
.||.. ..||  |.   ....|.... . . ...  |||..||||  |. .|...    |.  .. .| |..... . .|.  ||||..  .
giqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlv....aaylmlllg.vsleealelvrsqrpgavpnpgq
0048179 (Phosphotyrosine protein) phosphatases II 3-95 2e-09 32.8 In-house 49-134 (144) alignment 
Range on Protein: 3-95
Range on HMM: 49-134/144.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkiGGGPIVVHCSDTVSHSGVYCSVSIALeqckAEGvVDVFQVTKAIRRSKPGAVTTLVFI
.||.. ..||  |.   .  .|.... . . ..   |||..||||  |. .|...   . .     .| ...... . .|.  ||||..  ..
giqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgql
subfamily_PTPN1_pd Subfamily PTPN1 3-91 3.6e-09 30.8 In-house 164-256 (290) alignment 
Range on Protein: 3-91
Range on HMM: 164-256/290.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQ-KIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTT
...|  | ||  |. . | . |. . .| .    .   || |.|||  .  || .| |   | . ....    ||. .|  ..|. . | . |
ilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqt
subfamily_PTPRN_pd Subfamily PTPRN 3-91 7.8e-09 29.7 In-house 189-277 (297) alignment 
Range on Protein: 3-91
Range on HMM: 189-277/297.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIhRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSKPGAVTT
| ||    ||  |.  .....|.    |  .  .    |||||||| .  .|||. . . |..  |    .|.    . .|  .|| | |
vtqfhflswpeegvPasaksllefrrkvn.ksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvkt
subfamily_PTPN14_pd Subfamily PTPN14 3-92 1e-08 29.5 In-house 185-282 (300) alignment 
Range on Protein: 3-92
Range on HMM: 185-282/300.0
VIQFQVTDWPTDGIVREPRTVLQVIDDV---IH-RQQKI----GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
|. .| |||| .|. ..... |. ...|    .  ....       |..||||. |  .||   . . ..  . . ..|. .| . .|. .   | ||
vwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtl
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 3-94 4.7e-08 27.2 In-house 170-265 (287) alignment 
Range on Protein: 3-94
Range on HMM: 170-265/287.0
VIQFQVTDWPTDGIVRE----PRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF
| |... .|| ...        | ||.| . .  ...  . ||.|||..  .  ||.. .. . ... .  | ||| .|   .|  . . | . | 
vkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvq
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 3-65 2.7e-06 21.3 In-house 217-288 (350) alignment 
Range on Protein: 3-65
Range on HMM: 217-288/350.0
VIQFQVTDWPTDGIVREPRTVLQVID---DVIH----R--QQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQ
| |.||  |.  ... .|. .||...   |.|     .   ..  . ||.||||  |   |.....   |..
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsd
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 4-91 6.2e-15 50.0 In-house 164-253 (274) alignment 
Range on Protein: 4-91
Range on HMM: 164-253/274.0
IQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI--GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
. .  ||||     ....|.|.....| . ...     .|.|||||  .   |.. ..|||. | ..|.||||....  .|  . | | |
khywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqt
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 4-91 3.3e-13 44.4 In-house 136-224 (237) alignment 
Range on Protein: 4-91
Range on HMM: 136-224/237.0
IQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
 |.| | ||  |. ..  ..|.   ..|.| ...   || ..|||  | ..|..  .   | |.| . |||...  ..|   .|  . |
hqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqt
0049260 (Phosphotyrosine protein) phosphatases II 4-95 1.6e-09 33.2 In-house 55-139 (152) alignment 
Range on Protein: 4-95
Range on HMM: 55-139/152.0
IQFQVTDWPTDGiVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALeqckaeGVVDVFQVTKAIRRSKPGAVTTLVFI
||.. . || .| | .   .|. . ..|.. ..  |||..||||  |. .|...   . |        |..... . .|. .||||..  ..
iqylhlpwpDhg.vpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgql
0046846 (Phosphotyrosine protein) phosphatases II 4-94 7.3e-09 31.1 In-house 77-161 (176) alignment 
Range on Protein: 4-94
Range on HMM: 77-161/176.0
IQFQVTDWPTDGIVREpRTVLQVIDDVIHRQQKigGGPIVVHCSDTVSHSGVYCSVSialeQCKAEGVVDVFQVTKAIRRSKP-GAVTTLVF
||.....||  |.    . .|.... .  ....  |||..||||  .. .|...        .. |  ..|... . .|. .| |||.|  .
iqylhlpwpDhgvpdl.elllellefirealke..ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQ
0049772 (Phosphotyrosine protein) phosphatases II 4-92 1.3e-06 23.9 In-house 181-266 (314) alignment 
Range on Protein: 4-92
Range on HMM: 181-266/314.0
IQFQVTDWPTdGIVREPRTVLQVI---DDVihrqqkIGGGPIVVHCSDTVSHSGVYCSVSIALEQCkaeGVvDVFQVTKAIRRSKP-----GAVTTL
|..  ...|  | .  .. .....   ...        |||..|||.. .. .|... . . . ..   || .. .. . .|.  |     |.. .|
ikylripvpD.gsaplledfdeflefieea......dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieql
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 5-92 2.8e-17 57.5 In-house 166-252 (283) alignment 
Range on Protein: 5-92
Range on HMM: 166-252/283.0
QFQVTDWptdgIVREPRTV---LQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
 .|| ||    .  .. ..   |  .. ||  |..   |||||||| ..  ..|....| .... ..| |||||.| | .|  ...|| ||
hyqvidW....leygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtl
0044763 (Phosphotyrosine protein) phosphatases II 5-95 1e-07 27.3 In-house 80-160 (178) alignment 
Range on Protein: 5-95
Range on HMM: 80-160/178.0
QFQVTDWPTDGIVREPRTVLQVIDDVIhrqqKIGGGPIVVHCSDTVSHSGVYCSVSIALEQckaeGVvDVFQVTKAIRRSKPgAVTTLVFI
.. . |...  . .  . ... |....    .  |||..||||  |. ||. .   . ...    |. ..... . .|. .| .|..  ..
hipipDhgvpdllehflefvefieeal....dekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgql
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 5-49 1.6e-06 21.8 In-house 93-137 (440) alignment 
Range on Protein: 5-49
Range on HMM: 93-137/440.0
QFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDT
|..   ||  |. .    ||..|.|| . |.| | ||..||||  
qyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsag
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 5-91 4.5e-06 20.9 In-house 180-262 (307) alignment 
Range on Protein: 5-91
Range on HMM: 180-262/307.0
QFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkigggPIVVHCSDTVSHSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSKPGAVTT
..| ..||  |. .   | . ... |   .      |.|||||  |  ||   ..|.  ..  . .   |. .. . .|  .. |. |
hlqwenwpdrgvpqinltainlleavrydtn.....pvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqt
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 6-90 4e-07 24.0 In-house 188-267 (290) alignment 
Range on Protein: 6-90
Range on HMM: 188-267/290.0
FQVTDWPTDGIVREPRTVLQVIDDVihrqqKIGGGPIVVHCSDTVSHSGVYCSVSIALeQCKAEG-VVDVFQVTKAIRRSKPGAVT
...  ||   .     ..|...  .     .   ||.|||||  .  .| . .. ..| |.  .|  .|. .. .|.|.|. ..| 
lkikswpdksvalstlallrtlril.....rkasGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvq
subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 7-91 1.4e-07 25.9 In-house 164-244 (290) alignment 
Range on Protein: 7-91
Range on HMM: 164-244/290.0
QVTDWPTDGIVREPRTVLQVIDDVIHRQqkiggGPIVVHCSDTVSHSGVYCSVSIALEQCK-AEGVVDVFQVTKAIRRSKPGAVTT
.. .| .  . ....|.|..|. |  ..      |..||| | .|.| .  .. ..       .| | . .| ||.|. .  |.|.
llkgWnklnvqedtktllsliqkvkask.....tpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaits
subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 7-91 1.6e-07 25.0 In-house 194-273 (302) alignment 
Range on Protein: 7-91
Range on HMM: 194-273/302.0
QVTDWPTDGIVREPRTVLQVIDDVIHRQQKigggpIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
. . ||  |  .|. | |...      ...     ..||||  |  .|   ..   .. |. . | |. .. . .|. . ||| .
afsawpdhGapkeaytaldilkfcesykkn.....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqd
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 32-92 1.7e-12 42.0 In-house 185-245 (267) alignment 
Range on Protein: 32-92
Range on HMM: 185-245/267.0
HRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
. | . |. |.||.||| |  || .  .   ||. | |||.|.|.  . ||  ..| | |.
knqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtk
subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 37-93 4.1e-08 27.6 In-house 133-191 (199) alignment 
Range on Protein: 37-93
Range on HMM: 133-191/199.0
IGGGPIVVHCSDTVSHSGVYCSVSIALE---QCKaEGVVDVFQVTKAIRRSKPGAVTTLV
    |..|||||    .||. .. | .    . |   |||.|.|.| .|... | ...| 
ekdapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslq
subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 37-93 4.1e-08 27.6 In-house 132-190 (198) alignment 
Range on Protein: 37-93
Range on HMM: 132-190/198.0
IGGGPIVVHCSDTVSHSGVYCSVSIALE---QCKaEGVVDVFQVTKAIRRSKPGAVTTLV
    |..|||||    .||. .. | .    . |   |||.|.|.| .|... | ...| 
ekdapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslq
subfamily_CG42327_pd Subfamily CG42327 38-91 4.7e-07 23.8 In-house 246-300 (319) alignment 
Range on Protein: 38-91
Range on HMM: 246-300/319.0
GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTT
  ||.|||||| |  .|.  .  ||... .     ||. |.   .|| .  || |
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavlt
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 39-93 1.4e-12 41.7 In-house 371-425 (440) alignment 
Range on Protein: 39-93
Range on HMM: 371-425/440.0
GGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
| ||.|||   .  |||.|.|   ||| . .| .||||  . .| |.|  | || 
gppilvhclsgieesgvfctvmncleqlnndgaidvfqnlrllrlsrpnfvptlt
subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 42-89 4e-06 21.1 In-house 1-48 (69) alignment 
Range on Protein: 42-89
Range on HMM: 1-48/69.0
IVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAV
.|||||     .| . .. . . . |.| .||.|   . .|. .|  |
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmv