Gene PTPRD-55 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP112_AA protein Get Run
AqueP112_AA_1-99 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 1-98 4.1e-66 217.7 In-house 188-286 (301) alignment
Range on Protein: 1-98
Range on HMM: 188-286/301.0
WDVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL-VFIGIY
|||.|.||||||.||.|||||||||||||||||||||||||.|||||||||.|||||||||.||||||||||||||||||.|||||||||||  .. ||
wdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiy

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 2-91 3.1e-18 60.7 In-house 176-264 (315) alignment
Range on Protein: 2-91
Range on HMM: 176-264/315.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGgGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
.|.|...| ||. |. .   .....|  |   ...   |.||||||. | ..| .....  |.| .|| ..||... . .|. . ..| .
evvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqv

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 2-93 9.1e-14 46.2 In-house 176-266 (288) alignment
Range on Protein: 2-93
Range on HMM: 176-266/288.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
.. |.| . || .|. .  . .|.... |   .|.   |||.||||. |  .|.. ..  .... ..| ..||. . . .|....  | || 
eitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlk

subfamily_PTPN13_pd Subfamily PTPN13 2-91 1.3e-12 42.5 In-house 167-254 (273) alignment
Range on Protein: 2-91
Range on HMM: 167-254/273.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkiGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
.| ... ..||  |. ...  .||..  | . |.    ||||||||  .  ||.. .. ..|.  . .  .|| .. . .|. . | | |
evahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqt

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 2-93 3.1e-12 41.2 In-house 171-263 (281) alignment
Range on Protein: 2-93
Range on HMM: 171-263/281.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTLV
.| |.. | ||  |.  ... .|.  ..| . ..|    |.|.|||  |  .|.| ..  ......||   .|| .| . .|...   | |.|
eveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvv

0051082 (Phosphotyrosine protein) phosphatases II 2-93 2.9e-10 35.4 In-house 59-140 (151) alignment
Range on Protein: 2-93
Range on HMM: 59-140/151.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHrqqkIGGGPIVVHCSDTVSHSGVYCSVSIALEQckaegvVDVFQVTKAIRRSKPGAVTTLV
.|......|||. |.   . .||.... ...     ..||..||||  .. .|. . . . |..      |..... . .|.. ||.|..  
evlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnq

subfamily_ptpA1_pd Subfamily ptpA1 2-65 2.4e-06 21.5 In-house 187-255 (418) alignment
Range on Protein: 2-65
Range on HMM: 187-255/418.0
DVIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIG-----GGPIVVHCSDTVSHSGVYCSVSIALEQ
|. |.|   ||   |    . . |..  .  ||..|        ||.||||  | ..| .|.  | ...
ditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkk

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 3-92 1.3e-37 124.6 In-house 180-269 (305) alignment
Range on Protein: 3-92
Range on HMM: 180-269/305.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
|.|.|.|||| .|..... ..|..|..| ..|.|  | |..||||..|. .||...|.||||..|.|.|||||.|.|..|......|.||
vlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtl

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 3-93 3e-33 110.0 In-house 180-270 (290) alignment
Range on Protein: 3-93
Range on HMM: 180-270/290.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
|.|.|.| |. .| | .| |.|.||  ... | | | ..|||||||||. |.|.|.. .....|| |||.||||| |  |  ||| |.| .
vtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvq

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 3-96 7e-30 99.0 In-house 175-269 (287) alignment
Range on Protein: 3-96
Range on HMM: 175-269/287.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL-VFIG
| |.|.|.|.  | | ||.|.| ||.. .. |.| | ..|||||||||  |...|.. .....|| |||.||||| |  |  |||.| |   ...
vkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykf

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 3-92 8.8e-25 82.5 In-house 187-276 (298) alignment
Range on Protein: 3-92
Range on HMM: 187-276/298.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |...| ||  |. .. ..||.....|   ||. |  |..|.||. |  || .. ..  ||. |.| ||||||| |..|...||||.| 
vrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqte

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 3-92 3.5e-24 80.4 In-house 139-228 (250) alignment
Range on Protein: 3-92
Range on HMM: 139-228/250.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |.. . ||  |. .. ..||.....|   ||..| .|..|.||  |. || .. ..  ||. | | |||||.| |..|. .|.||..|
vrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesl

subfamily_PTPRD_pd Subfamily PTPRD 3-91 5.3e-24 79.8 In-house 179-266 (564) alignment
Range on Protein: 3-91
Range on HMM: 179-266/564.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||. |.||  |.  .....|..|..| . . . . ||||||||  |  .|... ... ||. |.|..||..|. ||.|. ..  | |
VrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqt

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 3-91 1.6e-23 78.3 In-house 177-265 (318) alignment
Range on Protein: 3-91
Range on HMM: 177-265/318.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| |...|.||  |.  .. ..|... .| . ||| | ||||||||  |   ||.. |.| ||. |||..|||||. | .|. ..  | |
vrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqt

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 3-91 2.2e-23 77.8 In-house 180-268 (319) alignment
Range on Protein: 3-91
Range on HMM: 180-268/319.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| .|| |.|| ... .. ...|... .. . ..|   ||||||||. |   | .. ....||. | |||.|||.. . .|  ..  | .
vkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqr

0050432 (Phosphotyrosine protein) phosphatases II 3-93 2.6e-21 71.7 In-house 199-286 (308) alignment
Range on Protein: 3-93
Range on HMM: 199-286/308.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQqkiGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
| .|. |.|| .|.  .|. .|. .. | ...   .|||||||||. |. .|... . ..||| ..|| ||||.. | .|. .||.|.|. 
vthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpe

0036941 (Phosphotyrosine protein) phosphatases II 3-94 5.5e-21 70.6 In-house 170-265 (297) alignment
Range on Protein: 3-94
Range on HMM: 170-265/297.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCK---AEGVVDVFQVTKAIRRSKPGAVTTLVF
| .|..|.|| .|.   |...|. |. | ...... .|||..||||. |. ||... . ..|.| .    || ||.... | .|. .||||.|| .
vthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleq

0046845 (Phosphotyrosine protein) phosphatases II 3-93 7.8e-21 70.1 In-house 167-261 (284) alignment
Range on Protein: 3-93
Range on HMM: 167-261/284.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQK-IGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEG---VVDVFQVTKAIRRSKPGAVTTLV
|..|..|.|| .|.  .|. .|. ...| . ...  ||||||||||. |. .|... . ..||| ..||   .|||... | .|. .||.|.|| 
vthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtle

0051299 (Phosphotyrosine protein) phosphatases II 3-93 1.1e-20 69.7 In-house 184-273 (288) alignment
Range on Protein: 3-93
Range on HMM: 184-273/288.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
|..|..|.|| .|.   |. .|. . .|.. ..  ||||.|||||. |. .|... . ..||| ..||.|||... | .|. .||.|.|. 
vthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpe

subfamily_PTPRA_pd Subfamily PTPRA 3-93 1.5e-20 68.4 In-house 193-282 (330) alignment
Range on Protein: 3-93
Range on HMM: 193-282/330.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGgPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
| ||  | ||  |.  ||. .|...  | . .|. .| |||||||  |  .| .. ..  ||. |||..||||.. | .|  .|  | |. 
vrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtde

0047943 (Phosphotyrosine protein) phosphatases II 3-94 1.8e-20 69.0 In-house 168-260 (273) alignment
Range on Protein: 3-94
Range on HMM: 168-260/273.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF
|..|..|.|| .|.   .  .|. |..| . .... ..||.|||||. |. .|... . ..|.| ..|| |||... | .|. .||.|.|. .
vthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeq

Y_phosphatase Protein-tyrosine phosphatase 3-92 3.1e-20 68.0 Pfam-A 135-223 (235) alignment
Range on Protein: 3-92
Range on HMM: 135-223/235.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |...|.||  |. ..|. .|..|..| ... .   ||.|||||. |. .|......|.|||..||. |||.|. | .|...||.|..|
vkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsl

Y_phosphatase Protein-tyrosine phosphatase 3-92 3.1e-20 68.0 In-house 135-223 (235) alignment
Range on Protein: 3-92
Range on HMM: 135-223/235.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQqKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |...|.||  |. ..|. .|..|..| ... .   ||.|||||. |. .|......|.|||..||. |||.|. | .|...||.|..|
vkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsl

DSPc_SM00195 3-92 4.4e-20 67.5 In-house 160-248 (263) alignment
Range on Protein: 3-92
Range on HMM: 160-248/263.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |.|...||  |.  ... ||...  | ......  ||||||||. |. .|......|.|.....|  ||.|.. |..| ..||.|.||
vtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtl

PTPc_SM00194 3-92 4.4e-20 67.5 In-house 160-248 (263) alignment
Range on Protein: 3-92
Range on HMM: 160-248/263.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |.|...||  |.  ... ||...  | ......  ||||||||. |. .|......|.|.....|  ||.|.. |..| ..||.|.||
vtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtl

PTPc_DSPc_SM00012 3-92 2.1e-19 65.0 In-house 2-93 (105) alignment
Range on Protein: 3-92
Range on HMM: 2-93/105.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIG-GGPIVVHCSDTVSHSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTL
| ....|.||  |. .|.  .|.....| . ..|.. ..|.|||||. |. .|... ..|.|.|...| . ||.||. |..|...||.|.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqte

0040438 (Phosphotyrosine protein) phosphatases II 3-95 2.6e-19 65.1 In-house 174-268 (317) alignment
Range on Protein: 3-95
Range on HMM: 174-268/317.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkiG-GGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF---I
| .|. |.|| .|.   |...|. .. | . ..  . |||..||||. |. .|... . ..|||.. || |||... | .|. .||||.|. .   .
vthfhytgWpdhgvppspdllldfleavreale..dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrfl

0040439 (Phosphotyrosine protein) phosphatases II 3-95 2.7e-19 65.2 In-house 142-235 (249) alignment
Range on Protein: 3-95
Range on HMM: 142-235/249.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVFI
| ..|.|||| .|.   . ..|. |. | . ....  |||..||||. |. .|...   ..||| . |. ||.... | .|. .||||... ..
vlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqy

0045450 (Phosphotyrosine protein) phosphatases II 3-95 2.8e-19 65.4 In-house 197-293 (307) alignment
Range on Protein: 3-95
Range on HMM: 197-293/307.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLVFI
|..|. |.|| .|.   . ..|. |. | . ...  .|||..||||. |. .|...   ..|.| ..||.   ||.... | .|. .||||... ..
vthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqy

0039614 (Phosphotyrosine protein) phosphatases II 3-94 4.6e-19 64.4 In-house 185-277 (297) alignment
Range on Protein: 3-94
Range on HMM: 185-277/297.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF
| .||.|.|| .|.   ....|.... | .....  .|||..||||. |. .|...   ..|||.. || |||... | .|. .||||.|. .
vthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsq

subfamily_PTPRK_pd Subfamily PTPRK 3-91 8e-19 62.6 In-house 175-262 (314) alignment
Range on Protein: 3-91
Range on HMM: 175-262/314.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKiGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||| . ||. ..  . ...|...  | . |.. . |.||||||     .|... ..| |.  . |||||||.. |..| .|.  | |
vrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmvet

0043336 (Phosphotyrosine protein) phosphatases II 3-94 2.6e-18 61.9 In-house 175-265 (278) alignment
Range on Protein: 3-94
Range on HMM: 175-265/278.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF
| ... ..|| .|.   . ..|. . .|.....   .||..||||. |. .|... . ..||| . || ||.... | .|. .||||.|. .
vthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsq

subfamily_Ptp69D_pd Subfamily Ptp69D 3-92 3.9e-18 60.6 In-house 184-272 (307) alignment
Range on Protein: 3-92
Range on HMM: 184-272/307.0
VIQFQVTDWPtDGIVRE-PRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
|.|.. | |. | .| | .|..|..|. | . ...   .|||||||  |..||.. .... |.|.|||  ||.|...| .|. ..  |. |
vvqyhytgWk.DskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsl

subfamily_CG7180_pd Subfamily CG7180 3-89 1.4e-17 58.3 In-house 182-273 (296) alignment
Range on Protein: 3-89
Range on HMM: 182-273/296.0
VIQFQVTDWPT-DGIVREPRTVLQVIDDVIHRQQKI----GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAV
| .||.| |.  | .     ......  |   ..|.      ||.||..|| .| ||||... ..||. . |. ||||.  | .|||.|. |
vklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLv

0042113 (Phosphotyrosine protein) phosphatases II 3-95 1.6e-17 59.2 In-house 140-232 (245) alignment
Range on Protein: 3-95
Range on HMM: 140-232/245.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVFI
||... ..|| .|.   ....|.... | . ... ..||..||||. |. .|... . ..||| ..|. |..... | .|. .||||.|. ..
vihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqy

subfamily_PTPRG_pd Subfamily PTPRG 3-91 2.8e-17 57.1 In-house 185-272 (563) alignment
Range on Protein: 3-91
Range on HMM: 185-272/563.0
VIQFQVTDWPTDGIVREPRTVLQVIDDViHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
|.|.. |.||  |    .  ||. .     . .|   ||||||||  |...|.|. ..  |.| ..| .|.||.. | ||  ..  |.|
vrqyhytkWPdhgvPehslpvLifvkks.saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqt

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 3-91 9.1e-17 56.1 In-house 179-269 (297) alignment
Range on Protein: 3-91
Range on HMM: 179-269/297.0
VIQFQVTDWPTDGIVR--EPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| |.| ..||.. . |  . ...|..|..| .  ..   ||..|||.  |   ||....   . . | |  ||.|.. | .|...|  | |
vkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqt

0045098 (Phosphotyrosine protein) phosphatases II 3-95 5.2e-16 54.3 In-house 156-261 (278) alignment
Range on Protein: 3-95
Range on HMM: 156-261/278.0
VIQFQVTDWPTDGIVREP--RTVLQVIDDVIHRQQK------------IGGGPIVVHCSDTVSHSGVYCSVSIALEQCkaEGVVDVFQVTKAIRRSKPG-
| ... . ||  |.  .|  . .|.... . .....             .|||..||||  |. .|... . . ||..  ||.||.... | .|. .|| 
vthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpgl

AVTTLVFI
||..| ..
avqnleqy

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 3-91 6e-16 52.6 In-house 174-261 (515) alignment
Range on Protein: 3-91
Range on HMM: 174-261/515.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGgGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||. |.||  |. .. ...|..| .|   ....   |...|||  |   ||..|.   . . |   .||||.. . ||. .|  | |
vtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqt

subfamily_PTPN6_pd Subfamily PTPN6 3-91 1.8e-15 51.8 In-house 188-282 (306) alignment
Range on Protein: 3-91
Range on HMM: 188-282/306.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIG---GGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTT
|.|.. ..||  |. ..| .||. ..|| ..|...     ||||||||. .   | .  . | |.. . .|.   .|. .. | .|. . | | |
vfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqt

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 3-91 1.8e-15 51.6 In-house 175-262 (315) alignment
Range on Protein: 3-91
Range on HMM: 175-262/315.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRqQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||| |.||  |. ..  ..|..| .|    ..    ...||||  |  .|| .|.   ..| | . .||||.. | .|. .|  | |
vtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqt

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 3-93 2e-15 51.9 In-house 187-278 (319) alignment
Range on Protein: 3-93
Range on HMM: 187-278/319.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGG-GPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
. ||    ||  |    |  ...... | | ..|  .  .||||||  |  .|||  . . |.. | |  |||... . .|. ..  |  ||
itqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlv

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 3-92 2.1e-15 51.7 In-house 180-274 (325) alignment
Range on Protein: 3-92
Range on HMM: 180-274/325.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-----GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |||.  |.  |  . | |.. ... | . ....     . .||.||||. |  .||. |.  ||..   |  ||.|.. | .|. .|  | | 
vkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetv

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 3-93 2.4e-15 51.8 In-house 151-242 (284) alignment
Range on Protein: 3-93
Range on HMM: 151-242/284.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGG-GPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
. ||    ||  |    |  ...... | | ..|  .  .||||||  |  .|||  . . |.. | |  |||... . .|. ..  |  ||
irqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlv

0037934 (Phosphotyrosine protein) phosphatases II 3-94 7.7e-15 50.6 In-house 135-230 (243) alignment
Range on Protein: 3-94
Range on HMM: 135-230/243.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQK-------IGGGPIVVHCSDTVSHSGVYCSVSIALEQCkaeGvVDVFQVTKAIRRSKPG-AVTTLVF
||... . ||  |.  .|  .|. .|.|.  ...        .|||..||||  |. .|...   . |...   | ||.... | .|. .|| ||.|. .
vihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsq





subfamily_PTPRB_pd Subfamily PTPRB 3-92 2.5e-14 48.0 In-house 181-271 (293) alignment
Range on Protein: 3-92
Range on HMM: 181-271/293.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQ-QKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
| |.. | ||  |.  ...|.|. .  | ... ..   .|||||||  |  .|.. ..   |.. . | .||.| .  ..|...   | | 
vrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqte

subfamily_PTPN12_pd Subfamily PTPN12 3-91 7.7e-14 46.3 In-house 172-262 (290) alignment
Range on Protein: 3-91
Range on HMM: 172-262/290.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTT
| ||. |.||  |. . . ..|..|..| ..|.     |.|||||  |   |. ... .. |. ||| .   .|||..   .|. .. .| |
vyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqt

0036282 (Phosphotyrosine protein) phosphatases II 3-95 3.4e-13 45.1 In-house 69-159 (174) alignment
Range on Protein: 3-95
Range on HMM: 69-159/174.0
VIQFQVTDWPTDGIVREPRtVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKaEGVVDVFQVTKAIRRSKPGAVTTLVFI
.||.. . || .|    .  .|.... | . ... .|||..||||  |. .|. .   . | . . |..||.... ...|. .||.|.|  ..
giqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQy

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 3-93 3.5e-13 44.1 In-house 154-251 (270) alignment
Range on Protein: 3-93
Range on HMM: 154-251/270.0
VIQFQVTDWPTDGIVREPR------TVLQVIDDV-IHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
.. |. ..|| .|..||.        .|... .|  .....  ..|..||||. |  .|.   . ||..  . .. ||| .. ...|. ..  | . .
lvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpe

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 3-91 1.7e-12 42.0 In-house 138-225 (239) alignment
Range on Protein: 3-91
Range on HMM: 138-225/239.0
VIQFQVTDWPTDGIVREPRTVLQVIdDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| |...| ||  |. .   .|| .    | ..   |  | |.|||  | ..| .  .   | |.| .  ||.|.  ||||  .|  | |
vyqyhftvwpdkgvpqyatavlglr.rkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqt

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 3-91 1.8e-12 42.0 In-house 139-226 (239) alignment
Range on Protein: 3-91
Range on HMM: 139-226/239.0
VIQFQVTDWPTDGIVREPRTVLQVIdDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| |...| ||  |. .   .|| .    | ..   |  | |.|||  | ..| .  .   | |.| .  ||.|.  ||||  .|  | |
vyqyhftvwpdkgvpqyatavlglr.rkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqt

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 3-93 1.9e-12 41.4 In-house 176-266 (439) alignment
Range on Protein: 3-93
Range on HMM: 176-266/439.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
|.||. . ||   .  .   ||. .  .   ..|   ||.|||||  | ..|   .. ||||| |.|  ||.  . | .|. .   | .|.
vlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalc

subfamily_PTPN23_pd Subfamily PTPN23 3-85 2.8e-12 41.0 In-house 173-259 (288) alignment
Range on Protein: 3-85
Range on HMM: 173-259/288.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIH---RQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSK
|   |.| ||  |.   | |.||..| | .    .|.    |.|||||  |  .||.. |  |...  | .|..|. || . .|. .
vshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqR

0051429 (Phosphotyrosine protein) phosphatases II 3-94 3.3e-12 42.1 In-house 122-213 (272) alignment
Range on Protein: 3-94
Range on HMM: 122-213/272.0
VIQFQVTDWPTDGIVREPrtVLQVIDDVIHrqqkigGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVD--------VFQVTKAIRRSKPGAVTTLVF
| ... ||||..|. .|.  .|.... . .      |||..||||  .. .|... . . |..  .| .||        .... . .|.  |||| |  .
vmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeq





0043147 (Phosphotyrosine protein) phosphatases II 3-99 3.5e-12 41.9 In-house 65-154 (172) alignment
Range on Protein: 3-99
Range on HMM: 65-154/172.0
VIQFQVTDWPTDGIVrEPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALeqckaEGVvDVFQVTKAIRRSKPGAVTTLVFIGIYL
.||.. . ||  |    .. .|.... . .....  |||..||||  |. .|. .   . |     .|. ..... . .|. .||||..  ..   .
giqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.....lgl.sleeavalvrekRpgavqnpsqyrfly

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 3-91 4.6e-12 40.0 In-house 134-221 (392) alignment
Range on Protein: 3-91
Range on HMM: 134-221/392.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIgGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
| ||..|.|| ... .   ..|..| .|     .    |...|||  | ..||  |.   . ..|   .||||..   ||| .|  | |
vaqfhftewPdkdvpkhtssllkfikevkadfGqy.thpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqt

subfamily_PTPN9_pd Subfamily PTPN9 3-84 2e-11 38.5 In-house 175-268 (297) alignment
Range on Protein: 3-84
Range on HMM: 175-268/297.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQ------------KIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRS
|. ||.. ||  |. ..  ..|.|.. | ..|             .. | |||||||  .  .| .... |.|.. . .|.|||... | .|  
vthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtq

0041856 (Phosphotyrosine protein) phosphatases II 3-92 3.1e-11 38.7 In-house 79-157 (182) alignment
Range on Protein: 3-92
Range on HMM: 79-157/182.0
VIQFQVTDWPTDGIVRePRTVLQVIDDVIHrqqkiGGGPIVVHCSDTVSHSGVYCSVSIALEQckaeGvVDVFQVTKAIRRSKPGAVTTL
.||.. . || .|.   ....|. |..|..      |||..||||  |. .|...   . ...    | |..... | .|. .||.|.|.
giqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitp

subfamily_PTPN3_pd Subfamily PTPN3 3-86 4.1e-11 37.3 In-house 173-255 (280) alignment
Range on Protein: 3-86
Range on HMM: 173-255/280.0
VIQFQVTDWPTDGIVREPRTVLQVIDDViHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKP
..|.| ..||  |.  ..  .|.... | .....    |.|||||  .  .||.  . .||    |.  | . .. . .|  . 
ilqlqylaWpdhgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqra

0048076 (Phosphotyrosine protein) phosphatases II 3-94 8.6e-10 34.0 In-house 47-131 (145) alignment
Range on Protein: 3-94
Range on HMM: 47-131/145.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKigGGPIVVHCSDTVSHSGVYCsvsiALEQCKAEGvVDVFQVTKAIRRSKPGAVTTLVF
.||.. ..||  |.   ....|.... . . ...  |||..||||  |. .|...    |.  .. .| |..... . .|.  ||||..  .
giqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlv....aaylmlllg.vsleealelvrsqrpgavpnpgq

0048179 (Phosphotyrosine protein) phosphatases II 3-95 2e-09 32.8 In-house 49-134 (144) alignment
Range on Protein: 3-95
Range on HMM: 49-134/144.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkiGGGPIVVHCSDTVSHSGVYCSVSIALeqckAEGvVDVFQVTKAIRRSKPGAVTTLVFI
.||.. ..||  |.   .  .|.... . . ..   |||..||||  |. .|...   . .     .| ...... . .|.  ||||..  ..
giqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgql

subfamily_PTPN1_pd Subfamily PTPN1 3-91 3.6e-09 30.8 In-house 164-256 (290) alignment
Range on Protein: 3-91
Range on HMM: 164-256/290.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQ-KIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTT
...|  | ||  |. . | . |. . .| .    .   || |.|||  .  || .| |   | . ....    ||. .|  ..|. . | . |
ilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqt

subfamily_PTPRN_pd Subfamily PTPRN 3-91 7.8e-09 29.7 In-house 189-277 (297) alignment
Range on Protein: 3-91
Range on HMM: 189-277/297.0
VIQFQVTDWPTDGIVREPRTVLQVIDDVIhRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSKPGAVTT
| ||    ||  |.  .....|.    |  .  .    |||||||| .  .|||. . . |..  |    .|.    . .|  .|| | |
vtqfhflswpeegvPasaksllefrrkvn.ksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvkt

subfamily_PTPN14_pd Subfamily PTPN14 3-92 1e-08 29.5 In-house 185-282 (300) alignment
Range on Protein: 3-92
Range on HMM: 185-282/300.0
VIQFQVTDWPTDGIVREPRTVLQVIDDV---IH-RQQKI----GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
|. .| |||| .|. ..... |. ...|    .  ....       |..||||. |  .||   . . ..  . . ..|. .| . .|. .   | ||
vwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtl

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 3-94 4.7e-08 27.2 In-house 170-265 (287) alignment
Range on Protein: 3-94
Range on HMM: 170-265/287.0
VIQFQVTDWPTDGIVRE----PRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLVF
| |... .|| ...        | ||.| . .  ...  . ||.|||..  .  ||.. .. . ... .  | ||| .|   .|  . . | . | 
vkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvq

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 3-65 2.7e-06 21.3 In-house 217-288 (350) alignment
Range on Protein: 3-65
Range on HMM: 217-288/350.0
VIQFQVTDWPTDGIVREPRTVLQVID---DVIH----R--QQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQ
| |.||  |.  ... .|. .||...   |.|     .   ..  . ||.||||  |   |.....   |..
vyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsd

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 4-91 6.2e-15 50.0 In-house 164-253 (274) alignment
Range on Protein: 4-91
Range on HMM: 164-253/274.0
IQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI--GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
. .  ||||     ....|.|.....| . ...     .|.|||||  .   |.. ..|||. | ..|.||||....  .|  . | | |
khywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqt

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 4-91 3.3e-13 44.4 In-house 136-224 (237) alignment
Range on Protein: 4-91
Range on HMM: 136-224/237.0
IQFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKI-GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
 |.| | ||  |. ..  ..|.   ..|.| ...   || ..|||  | ..|..  .   | |.| . |||...  ..|   .|  . |
hqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqt

0049260 (Phosphotyrosine protein) phosphatases II 4-95 1.6e-09 33.2 In-house 55-139 (152) alignment
Range on Protein: 4-95
Range on HMM: 55-139/152.0
IQFQVTDWPTDGiVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALeqckaeGVVDVFQVTKAIRRSKPGAVTTLVFI
||.. . || .| | .   .|. . ..|.. ..  |||..||||  |. .|...   . |        |..... . .|. .||||..  ..
iqylhlpwpDhg.vpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgql

0046846 (Phosphotyrosine protein) phosphatases II 4-94 7.3e-09 31.1 In-house 77-161 (176) alignment
Range on Protein: 4-94
Range on HMM: 77-161/176.0
IQFQVTDWPTDGIVREpRTVLQVIDDVIHRQQKigGGPIVVHCSDTVSHSGVYCSVSialeQCKAEGVVDVFQVTKAIRRSKP-GAVTTLVF
||.....||  |.    . .|.... .  ....  |||..||||  .. .|...        .. |  ..|... . .|. .| |||.|  .
iqylhlpwpDhgvpdl.elllellefirealke..ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQ

0049772 (Phosphotyrosine protein) phosphatases II 4-92 1.3e-06 23.9 In-house 181-266 (314) alignment
Range on Protein: 4-92
Range on HMM: 181-266/314.0
IQFQVTDWPTdGIVREPRTVLQVI---DDVihrqqkIGGGPIVVHCSDTVSHSGVYCSVSIALEQCkaeGVvDVFQVTKAIRRSKP-----GAVTTL
|..  ...|  | .  .. .....   ...        |||..|||.. .. .|... . . . ..   || .. .. . .|.  |     |.. .|
ikylripvpD.gsaplledfdeflefieea......dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieql

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 5-92 2.8e-17 57.5 In-house 166-252 (283) alignment
Range on Protein: 5-92
Range on HMM: 166-252/283.0
QFQVTDWptdgIVREPRTV---LQVIDDVIHRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
 .|| ||    .  .. ..   |  .. ||  |..   |||||||| ..  ..|....| .... ..| |||||.| | .|  ...|| ||
hyqvidW....leygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtl

0044763 (Phosphotyrosine protein) phosphatases II 5-95 1e-07 27.3 In-house 80-160 (178) alignment
Range on Protein: 5-95
Range on HMM: 80-160/178.0
QFQVTDWPTDGIVREPRTVLQVIDDVIhrqqKIGGGPIVVHCSDTVSHSGVYCSVSIALEQckaeGVvDVFQVTKAIRRSKPgAVTTLVFI
.. . |...  . .  . ... |....    .  |||..||||  |. ||. .   . ...    |. ..... . .|. .| .|..  ..
hipipDhgvpdllehflefvefieeal....dekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgql

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 5-49 1.6e-06 21.8 In-house 93-137 (440) alignment
Range on Protein: 5-49
Range on HMM: 93-137/440.0
QFQVTDWPTDGIVREPRTVLQVIDDVIHRQQKIGGGPIVVHCSDT
|..   ||  |. .    ||..|.|| . |.| | ||..||||  
qyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsag

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 5-91 4.5e-06 20.9 In-house 180-262 (307) alignment
Range on Protein: 5-91
Range on HMM: 180-262/307.0
QFQVTDWPTDGIVREPRTVLQVIDDVIHRQQkigggPIVVHCSDTVSHSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSKPGAVTT
..| ..||  |. .   | . ... |   .      |.|||||  |  ||   ..|.  ..  . .   |. .. . .|  .. |. |
hlqwenwpdrgvpqinltainlleavrydtn.....pvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqt

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 6-90 4e-07 24.0 In-house 188-267 (290) alignment
Range on Protein: 6-90
Range on HMM: 188-267/290.0
FQVTDWPTDGIVREPRTVLQVIDDVihrqqKIGGGPIVVHCSDTVSHSGVYCSVSIALeQCKAEG-VVDVFQVTKAIRRSKPGAVT
...  ||   .     ..|...  .     .   ||.|||||  .  .| . .. ..| |.  .|  .|. .. .|.|.|. ..| 
lkikswpdksvalstlallrtlril.....rkasGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvq

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 7-91 1.4e-07 25.9 In-house 164-244 (290) alignment
Range on Protein: 7-91
Range on HMM: 164-244/290.0
QVTDWPTDGIVREPRTVLQVIDDVIHRQqkiggGPIVVHCSDTVSHSGVYCSVSIALEQCK-AEGVVDVFQVTKAIRRSKPGAVTT
.. .| .  . ....|.|..|. |  ..      |..||| | .|.| .  .. ..       .| | . .| ||.|. .  |.|.
llkgWnklnvqedtktllsliqkvkask.....tpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaits

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 7-91 1.6e-07 25.0 In-house 194-273 (302) alignment
Range on Protein: 7-91
Range on HMM: 194-273/302.0
QVTDWPTDGIVREPRTVLQVIDDVIHRQQKigggpIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTT
. . ||  |  .|. | |...      ...     ..||||  |  .|   ..   .. |. . | |. .. . .|. . ||| .
afsawpdhGapkeaytaldilkfcesykkn.....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqd

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 32-92 1.7e-12 42.0 In-house 185-245 (267) alignment
Range on Protein: 32-92
Range on HMM: 185-245/267.0
HRQQKIGGGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTL
. | . |. |.||.||| |  || .  .   ||. | |||.|.|.  . ||  ..| | |.
knqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtk

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 37-93 4.1e-08 27.6 In-house 133-191 (199) alignment
Range on Protein: 37-93
Range on HMM: 133-191/199.0
IGGGPIVVHCSDTVSHSGVYCSVSIALE---QCKaEGVVDVFQVTKAIRRSKPGAVTTLV
    |..|||||    .||. .. | .    . |   |||.|.|.| .|... | ...| 
ekdapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslq

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 37-93 4.1e-08 27.6 In-house 132-190 (198) alignment
Range on Protein: 37-93
Range on HMM: 132-190/198.0
IGGGPIVVHCSDTVSHSGVYCSVSIALE---QCKaEGVVDVFQVTKAIRRSKPGAVTTLV
    |..|||||    .||. .. | .    . |   |||.|.|.| .|... | ...| 
ekdapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslq

subfamily_CG42327_pd Subfamily CG42327 38-91 4.7e-07 23.8 In-house 246-300 (319) alignment
Range on Protein: 38-91
Range on HMM: 246-300/319.0
GGGPIVVHCSDTVSHSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTT
  ||.|||||| |  .|.  .  ||... .     ||. |.   .|| .  || |
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavlt

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 39-93 1.4e-12 41.7 In-house 371-425 (440) alignment
Range on Protein: 39-93
Range on HMM: 371-425/440.0
GGPIVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLV
| ||.|||   .  |||.|.|   ||| . .| .||||  . .| |.|  | || 
gppilvhclsgieesgvfctvmncleqlnndgaidvfqnlrllrlsrpnfvptlt

subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 42-89 4e-06 21.1 In-house 1-48 (69) alignment
Range on Protein: 42-89
Range on HMM: 1-48/69.0
IVVHCSDTVSHSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAV
.|||||     .| . .. . . . |.| .||.|   . .|. .|  |
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmv