Gene PTPRD-56 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP113_AA protein Get Run
AqueP113_AA_812-971 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
fn3 Fibronectin type III domain 137-211 1.3e-11 37.7 Pfam-A 2-79 (85) alignment
Range on Protein: 137-211
Range on HMM: 2-79/85.0
APSSLTEVSKTATTITVSWTALD--SSDADGYVVNVTSDTDT--VQTVQVEGSSNdTIVLNGLRELTTYSIIVRAYQQL
||. |.  . |.|..|.||.. .  ... .|| | . .....   ....|..... . .|.||.. |.|.. |.|. . 
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavnga

fn3 Fibronectin type III domain 324-389 2.4e-07 24.0 Pfam-A 3-76 (85) alignment
Range on Protein: 324-389
Range on HMM: 3-76/85.0
PNDVKGFILNASSIKVNWTNS----IGTNGYVIEYTTGGVT--RNVVSTSEDE--VVLTNLSPMSTYTISVYSY
| ...    ...|. ..|. .        || .|| . | .   . .......  |.||.| | ..|...|...
PenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqav

fn3 Fibronectin type III domain 408-494 2.8e-12 39.8 Pfam-A 1-82 (85) alignment
Range on Protein: 408-494
Range on HMM: 1-82/85.0
SPVTSLSVSNVSTTGITVSWNIP-SSDNYVTYYTIFYTPSCPQLssVNETVSVGPHqsttTYSYTLAGLYSGMNYTITVRAGNVLGGS
|... ||||.|..| .|.||. | . .  .|.|.. | ..  .   .  ...| ..    |.|.|| ||  |..|...|.| |  |..
saPenlsvsevtstsltlsWsppkdgggpitgYeveyrekggge..ewkeftvprt....ttsvtltgLkpgteYefrVqavngageg

fn3 Fibronectin type III domain 525-589 1.1e-07 25.0 Pfam-A 18-85 (85) alignment
Range on Protein: 525-589
Range on HMM: 18-85/85.0
LTWNEVNcsKHNGLITGYTVVISNS-----SITYTLTSTERYIILKVLAFGTEYNISVAAENSAGIGPFS
|.|.. .  . .| ||||.|  ...     . ..|...|..  .|. |  ||||...|.| | || ||.|
lsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpeS

fn3 Fibronectin type III domain 606-697 1.5e-08 27.9 Pfam-A 8-84 (85) alignment
Range on Protein: 606-697
Range on HMM: 8-84/85.0
VSSImDTTWAVISWSVPSyiPSDYPIITYEIGYHMLQSGNcsmvydddinlqVFNLSNVSSNDTFTIITRLNSNTCYIFGIRAYSDNGYGAW
||..  .| ...||| |.  . . ||  ||. | . ..|.            . .  .|... |  ..| |. .| | | ..|....|.| .
vsev.tstsltlsWsppk..dgggpitgYeveyrekggge............ewkeftvprtttsvtltgLkpgteYefrVqavngagegpe

0049772 (Phosphotyrosine protein) phosphatases II 813-971 1.4e-15 53.3 In-house 25-281 (314) alignment
Range on Protein: 813-971
Range on HMM: 25-281/314.0
LNTHSLKSGEEKPCTIGYSEENKPFNRFKNITVYDdNRIILatnPNLDMCQREYINASYVDGYsSNGIVREPHT--------------------------
||..||    |. ..... ..|.  ||...|  .| || ||   |.|..    |||||||||.  . |. . ..                          
lnrrslsvlpeltilvadlflnrdknryldilpad.nrvil...pglpvsgsdyinasyvdgf.lkfIatqgpleitvvdfreepvlyyngwrmvlrgdl

---------------------------------------------------------------------------ILQVIDDV---IHRQqkIGGGPVVV
                                                                           .|. .|..   |..     ||||.|
nvrdivmsrdevladelsrLdaAlgKtpllildgngneptaadlellkeelydpelferlgikylripvpDgsaplledfdeflefieea..dkggpvlv

HCSDTVSRSGVYCSVSIALEQCkaeGVvDVFQVTKAIRRSKP-----GAVTTLEQYTSIYDVIDMYFK
||.. ..|.|... . . . ..   || .. .. . .|.  |     |.. .||||  |.... .|.|
HCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefilealleylk

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 815-877 4.3e-25 83.0 In-house 21-83 (301) alignment
Range on Protein: 815-877
Range on HMM: 21-83/301.0
THSLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQREYINASYVDGYSS
 ..||.||.|.||.|.|||||..||||||||||||||||...||||.||||||||||.||||.
ykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgyse

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 815-877 1.7e-07 25.0 In-house 26-86 (392) alignment
Range on Protein: 815-877
Range on HMM: 26-86/392.0
THSLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYSS
 | | . .  | |..  | |.. ||.|||  || .|..|      |. ...|.||||.... .
fhdlpgpdiypqtvaqkeinlkknryknilpydsarvklevid..dipdsdylnasyipsfdn

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 815-877 7.8e-07 23.2 In-house 25-85 (315) alignment
Range on Protein: 815-877
Range on HMM: 25-85/315.0
THSLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYSS
 | |   .  . ...  ..| . ||.|||  .| .|..|      |  ...||||||. .. .
fhdlpdPdiyrqrvaretinfkknryknilPldsarvklevid..dsPdsdyinasyiksvdd

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 816-877 6.4e-06 20.3 In-house 31-90 (315) alignment
Range on Protein: 816-877
Range on HMM: 31-90/315.0
HSLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
 |.  |. .|  .    |||  ||. ||  ||  |. |    | .  . .|.||...|||. 
esipggqlhpldvakkienkqknryiniiaydksrvqlpllendp..hsdyvnanfidGynk

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 817-965 1.8e-20 67.7 In-house 30-189 (440) alignment
Range on Protein: 817-965
Range on HMM: 30-189/440.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVD-------------GYSSNGIVREPHTILQVIDDVIHRQQKIGG
 | ||  .|. |    .||  ||..|| .|| .|..|       . . .||||||..             |.  .|. .    .|..|.|| . |.| | 
llpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevk..gvpdsdyinasyingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagn

GPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDV
||..||||  ..|.||  .|   | ..|    .|.| . ...| ..|  | | |||. ....
gpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvhea

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 817-877 2.1e-13 45.1 In-house 30-87 (305) alignment
Range on Protein: 817-877
Range on HMM: 30-87/305.0
SLKSGeEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
|| .  |... .| .|.||  ||.|.||..||.||||.....||  ...||||||||||..
slyee.eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdgykr

subfamily_PTPRD_pd Subfamily PTPRD 817-877 6.1e-12 39.9 In-house 31-89 (564) alignment
Range on Protein: 817-877
Range on HMM: 31-89/564.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmCQREYINASYVDGYSS
....|.. ...    ..||. ||..||. || .|..| . ..    . .|||||..||| .
kieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegd..egsDYINAsfidgyrk

DSPc_SM00195 817-877 3.5e-09 31.7 In-house 9-67 (263) alignment
Range on Protein: 817-877
Range on HMM: 9-67/263.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmCQREYINASYVDGYSS
...| ..|..| .  ..||  ||.||| .||..|..| ....    . .||||.|..|...
leestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgank

PTPc_SM00194 817-877 3.5e-09 31.7 In-house 9-67 (263) alignment
Range on Protein: 817-877
Range on HMM: 9-67/263.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmCQREYINASYVDGYSS
...| ..|..| .  ..||  ||.||| .||..|..| ....    . .||||.|..|...
leestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgank

subfamily_PTPN12_pd Subfamily PTPN12 817-877 6.6e-07 23.5 In-house 23-81 (290) alignment
Range on Protein: 817-877
Range on HMM: 23-81/290.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
 .|. .. . . | .|||.  ||.|.|  || .|. | .. . .  . .||||... | ..
kykaekvysteagekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgveg

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 817-876 3.5e-06 20.4 In-house 26-83 (515) alignment
Range on Protein: 817-876
Range on HMM: 26-83/515.0
SLKSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYS
 |   .  | |.   | | . ||.|||  || .|..|      |  . .|.||||. .. 
dlpgpniypqtvaqeeinfkknryknilPydsvrvklevin..dnPhsdyfnasyipsfd

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 818-877 3.8e-15 50.5 In-house 29-89 (290) alignment
Range on Protein: 818-877
Range on HMM: 29-89/290.0
LKSGE-EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQREYINASYVDGYSS
|.||| |.  |.| ...||. |||.|| |||||||.|   ..   |. |||||.|..||. 
ldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgyke

0043336 (Phosphotyrosine protein) phosphatases II 819-970 1e-31 105.9 In-house 30-277 (278) alignment
Range on Protein: 819-970
Range on HMM: 30-277/278.0
KSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldMCQREYINASYVDGYS------------------------------------------
 |    ...|....|||..||.|.|  || .|..|   ..       ||||||||||.                                          
lsfkldtysiallpenkdknrykdilpydhsrvklsllgg..dldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvelgr

----------------------------------------SNGIVR-----------------EPHTILQVIDDVIHRQQkIGGGPVVVHCSDTVSRSGV
                                         .| .|                  . ..|. . .|.....   .|||.||||. |.|.|.
vkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngpvlVHCsaGvgRTGt

YCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
.. . ..||| . || ||.... | .|. .||||.|..||  .|... .|.
fialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl

subfamily_Sponge-PTP3_pd Subfamily Sponge-PTP3 819-877 3.9e-10 33.8 In-house 33-86 (95) alignment
Range on Protein: 819-877
Range on HMM: 33-86/95.0
KSGEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcqreYINASYVDGYSS
      | |.| || | | ||| ||  ||  |..|.|. . |     |||| .||||. 
smtsgapytvgsseanipknrflnifpydatrvvlttkrdsd.....yinacfvdgyar

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 819-877 3.7e-09 31.1 In-house 25-82 (281) alignment
Range on Protein: 819-877
Range on HMM: 25-82/281.0
KS-GEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
.. | ... |  ...||.  ||..||. ||  |. .. | .    . .||||..|.||..
aaigvdntataskadenvlknrYsnivaYDatrvkvtpneenk..ntDYinanfvpgykg

0039614 (Phosphotyrosine protein) phosphatases II 820-973 1.9e-34 114.9 In-house 43-292 (297) alignment
Range on Protein: 820-973
Range on HMM: 43-292/297.0
SGEEkPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMcQREYINASYVDGYSS------------------------------------------
|  . ...|....|||..||.|.|  ||..|..| .... |.    ||||||||||.                                           
slkp.dysiallpenkdknrykdilpydhsrvklkpedgvdl.dsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr

-------------------------------------------------------NGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYC
                                                       .|.   . ..|.... | .....  .||||.||||. |.|.|...
kcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfi

SVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLH
   ..|||.. || |||... | .|. .||||.|..||  .||.. ...| .
aaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk

0040438 (Phosphotyrosine protein) phosphatases II 821-976 1.5e-34 115.1 In-house 30-282 (317) alignment
Range on Protein: 821-976
Range on HMM: 30-282/317.0
GEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldMCQREYINASYVDGY---------------------------------------------
    ...... .|||..||...|  ||..|..|   ..       |||||||||.                                             
lkldtysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgrek

-------------------------------------------------------SSNGIVREPHTILQVIDDVIHRQQkiG-GGPVVVHCSDTVSRSGV
                                                          |.   | ..|. .. | . ..  . ||||.||||. |.|.|.
caqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale..dpggpvlVHCsaGvgRtGt

YCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTY
.. . ..|||.. || |||... | .|. .||||.|.|||  .||.. .|.| . |.
fiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltl

subfamily_PTPRB_pd Subfamily PTPRB 821-878 3.8e-08 27.7 In-house 38-93 (293) alignment
Range on Protein: 821-878
Range on HMM: 38-93/293.0
GEEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYSSN
|... ...  ...|.  ||..||  || .|. ||.    |  . .||||.|..||.|.
gkdqavkaaelavnraknrytnilpydhsrvkLaalk..desgsDYinanyipgynsp

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 822-876 1.9e-07 25.6 In-house 44-96 (298) alignment
Range on Protein: 822-876
Range on HMM: 44-96/298.0
EEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYS
||.  ... ..|||  ||. .|  .|  |..| ..   .  . .|||||....|.
eeeekevarkpenkkkNRyadiialdssRvvLeked..adeesdYiNAsflhayk

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 822-873 4.3e-06 20.8 In-house 21-66 (283) alignment
Range on Protein: 822-873
Range on HMM: 21-66/283.0
EEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldmcqrEYINASYVD
 .....|  ..|||..||...| ..| .|. | ....      .||||... 
pdldadiasadenkrknrnqeivpadqwrvelksesr......dyinavfip

subfamily_PTPN14_pd Subfamily PTPN14 822-873 6.7e-06 20.3 In-house 37-85 (300) alignment
Range on Protein: 822-873
Range on HMM: 37-85/300.0
EEKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmcQREYINASYVD
|.  .. .  .||.. ||||..  |.|||. |... .    . .||||| . 
edallstaklpenaeknrfkdvlPyednrvelsptken...stgyinassik

0050432 (Phosphotyrosine protein) phosphatases II 823-978 1e-36 122.2 In-house 57-307 (308) alignment
Range on Protein: 823-978
Range on HMM: 57-307/308.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILatnpnlDmCQREYINASYVDGY-----------------------------------------------
  ...... .|||..||.|.|  || .|..|      |     ||||||||||                                               
lleysvallpenkdkNrykdilpydhsRVkl......d.egsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrek

----------------------------------------------------------SSNGIVREPHTILQVIDDVIHRQqkiGGGPVVVHCSDTVSRS
                                                             |.  .|  .|. .. | ...   .|||.|||||. |.|.
caqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl...pggpivVHCsaGvGRt

GVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYAN
|... . ..||| ..|| ||||.. | .|. .||.|.|.|||  .|... .|.||. |..|
GtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklkltkln

0046845 (Phosphotyrosine protein) phosphatases II 823-978 3.5e-35 117.2 In-house 17-282 (284) alignment
Range on Protein: 823-978
Range on HMM: 17-282/284.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNlDMCQREYINASYVDGY-----------------------------------------------
. ...... .||.  ||.|.| .||..|..| . .. |.   .||||||||||                                               
llslsvallpenlsknRykdilpydhsRVklksldg.dledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelveng

------------------------------------------------------------SSNGIVREPHTILQVIDDVIHRQQK-IGGGPVVVHCSDTV
                                                              .|.  .|  .|. ...| . ...  ||||.|||||. |
rekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGv

SRSGVYCSVSIALEQCKAEG---VVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYAN
.|.|... . ..||| ..||   .|||... | .|. .||.|.|||||  .|... .|.||. |...
gRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklkltlle

0047943 (Phosphotyrosine protein) phosphatases II 823-970 3.7e-33 110.6 In-house 27-272 (273) alignment
Range on Protein: 823-970
Range on HMM: 27-272/273.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILatnpnlDMCQREYINASYVDGYS----------------------------------------------
. ...... .||| .||.|.|  ||..|..|      ..    ||||||||||                                               
lltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgrekca

---------------------------------------------------------SNGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSG
                                                          .|.   .  .|. |..| . .... ..||||||||. |.|.|
qYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtg

VYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
... . ..|.| ..|| |||... | .|. .||.|.|.|||  .|... .|.
tfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl

0045450 (Phosphotyrosine protein) phosphatases II 823-970 1.6e-31 105.6 In-house 44-304 (307) alignment
Range on Protein: 823-970
Range on HMM: 44-304/307.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdMCQREYINASYV--------DGY---------------------------------------
  ...|....|||..||.|.|  ||..|..| . ..  .    |||||||        |||                                       
lgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelv

---------------------------------------------------------------SSNGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCS
                                                                  |.   . ..|. |. | . ...  .||||.||||
elgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCs

DTVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
. |.|.|...   ..|.| ..||.   ||.... | .|. .||||...|||  .|... ...
aGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 823-878 8e-12 39.7 In-house 36-85 (287) alignment
Range on Protein: 823-878
Range on HMM: 36-85/287.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILAtnpnldMCQREYINASYVDGYSSN
|.  |.. ...||. ||...| |.|..|..|        .. .||||...|||...
edevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykek

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 823-877 2.3e-09 31.7 In-house 37-89 (319) alignment
Range on Protein: 823-877
Range on HMM: 37-89/319.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldMCQREYINASYVDGYSS
..  .    ||||. ||..||  ||  |..|.. ..  . . .|||||..|||  
ndtfdsaskeenkkknryqnilaydrtrvvlseldg..vegsdyinasfidgyqe

subfamily_PTPRG_pd Subfamily PTPRG 823-877 3.8e-09 30.3 In-house 36-89 (563) alignment
Range on Protein: 823-877
Range on HMM: 36-89/563.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQrEYINASYVDGYSS
. ...    .|||  ||  ||. ||  |. |.  |. .    .||||.|.|||  
dldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyidGyqk

subfamily_Ptp69D_pd Subfamily Ptp69D 823-876 1.1e-08 29.5 In-house 37-88 (307) alignment
Range on Protein: 823-876
Range on HMM: 37-88/307.0
EKPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYS
.| ....  .||.  ||...|. .|..|..|.. .  .  . .|||||.. || 
dkstkvsekkenalknRyedikafDktRvkLkkingke..dsdYinasfikgyk

0051299 (Phosphotyrosine protein) phosphatases II 824-970 3.3e-34 114.0 In-house 39-286 (288) alignment
Range on Protein: 824-970
Range on HMM: 39-286/288.0
KPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNldMCQREYINASYVDGYS-----------------------------------------------
 ...... .||.. ||...|  ||..|..| . ..  .    ||||||.|||                                                
ltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaq

---------------------------------------------------------SNGIVREPHTILQVIDDVIHRQQkIGGGPVVVHCSDTVSRSGV
                                                          .|.   |  .|. . .|.. ..  ||||||||||. |.|.|.
Ywplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgt

YCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
.. . ..||| ..||.|||... | .|. .||.|.|.|||  .|... .|.
fialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl

0036941 (Phosphotyrosine protein) phosphatases II 824-975 4.3e-34 113.6 In-house 29-282 (297) alignment
Range on Protein: 824-975
Range on HMM: 29-282/297.0
KPCTIGYSEENKPFNRFKNITVYDDNRIILatnpnlDMCQREYINASYVDGYS-----------------------------------------------
 ..... ..||.. ||.|.|  ||..|..|      |     ||||||||||.                                               
gslsvallpenleknRykdilpydhtRVkl......ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaq

---------------------------------------------------------SNGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSG
                                                          .|.   | ..|. |. | ...... .||||.||||. |.|||
ywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsg

VYCSVSIALEQCK---AEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHST
... . ..|.| .    || ||.... | .|. .||||.|||||  .|... ...| . |
tfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkklt

0045098 (Phosphotyrosine protein) phosphatases II 824-971 2e-26 88.4 In-house 23-273 (278) alignment
Range on Protein: 824-971
Range on HMM: 23-273/278.0
KPCTIGYSEENKPFNRFKNITVYDDNRIIlatnpnldmcqrEYINASYVDGYsS----------------------------------------------
  .| .  ..|...||.|.|  || .|..            .||||||.||| .                                              
seitpalylgnldknRykdilpydhsrVk............dYINAsyidgy.pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqy

---------------------------------------------------------NGIVREP--HTILQVIDDVIHRQQK------------IGGGPV
                                                         .|.  .|    .|.... . .....             .||||
wpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpv

VVHCSDTVSRSGVYCSVSIALEQCkaEGVVDVFQVTKAIRRSKPG-AVTTLEQYTSIYDVIDMYFK
.||||  |.|.|... . . ||..  ||.||.... | .|. .|| ||..||||  .|... ....
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 824-877 4.3e-07 24.3 In-house 37-88 (288) alignment
Range on Protein: 824-877
Range on HMM: 37-88/288.0
KPCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYSS
|  |.|   .|.. ||..||  || .|. |   .. .  . .||||||.||. .
ksvtagrlavnakknRyrnilpyDekrvklkkleeea..gaDYinasyidgekk

0040439 (Phosphotyrosine protein) phosphatases II 825-970 1.5e-29 98.7 In-house 2-246 (249) alignment
Range on Protein: 825-970
Range on HMM: 2-246/249.0
PCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQreYINASYVDGYS------------------------------------------------
...... .|||. ||...|  || .|..|   |.|  .   ||||||.|||                                                 
eysvallpenkdknrypdilpydhsrvklsilpglflsd..yinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqy

----------------------------------------------------SNGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYCSV
                                                      |.   . ..|. |. | . ....  ||||.||||. |.|.|...  
wplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaa

SIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
 ..||| . |. ||.... | .|. .||||...|||  .|... ...
ylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell

0037934 (Phosphotyrosine protein) phosphatases II 825-970 3.6e-21 71.3 In-house 1-242 (243) alignment
Range on Protein: 825-970
Range on HMM: 1-242/243.0
PCTIGYSEENKPFNRFKNITVYDDNRIILatnpnlDMcqREYINASYVDGYS----------------------------SNGIV---------------
...|. ..||.. ||...|  ||..|..|      .     ||||......                             .. ||               
sfsiallpenlsknrysdilpydhsrvkl......eg..sdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaq

---------------------------------------------------------REPHTILQVIDDVIHRQQK-------IGGGPVVVHCSDTVSRS
                                                          .|  .|. .|.|.  ...        .||||.||||  |.|.
ywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt

GVYCSVSIALEQCkaeGvVDVFQVTKAIRRSKPG-AVTTLEQYTSIYDVIDMYF
|...   . |...   | ||.... | .|. .|| ||.|..||  .|... ...
Gtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallell

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 825-877 1.1e-07 26.2 In-house 24-70 (267) alignment
Range on Protein: 825-877
Range on HMM: 24-70/267.0
PCTIGYSEENKPFNRFKNITVYDDNRIILATNPNLdmcqreYINASYVDGYSS
 ..  ..|.|. .||. .   |||.|.|| |. .       |||||||.||  
tisqsiaeknqernrlddnlpyddtrvilrtkeee......yinasyvegykt

0042113 (Phosphotyrosine protein) phosphatases II 826-970 5.1e-28 93.5 In-house 1-243 (245) alignment
Range on Protein: 826-970
Range on HMM: 1-243/245.0
CTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDMCQreYINASYVDGYS-------------------------------------------------
..... .|||..||...|  ||..|..|   ..   .   ||||||||||                                                  
ysvallpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqyw

----------------------------------SNGIVRE-----------------PHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSI
                                   .. .||                 . ..|.... | . ... ..|||.||||. |.|.|... . .
plgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaayl

ALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
.||| ..|. |..... | .|. .||||.|..||  .|... ...
mleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell

subfamily_PTPRA_pd Subfamily PTPRA 826-876 1.2e-07 26.0 In-house 50-98 (330) alignment
Range on Protein: 826-876
Range on HMM: 50-98/330.0
CTIGYSEENKPFNRFKNITVYDDNRIILATNPNLDmcQREYINASYVDGYS
. .   ||||  ||. ||  || .|.||..    .  . .|||||..||| 
lelaskeenkeknrvvnilPydfsrvilsvkeGve..esdyinasfidGyk

subfamily_PTPN6_pd Subfamily PTPN6 827-875 2.8e-08 28.1 In-house 47-92 (306) alignment
Range on Protein: 827-875
Range on HMM: 47-92/306.0
TIGYSEENKPFNRFKNITVYDDNRIILAtnpNLDMCQREYINASYVDGY
. |   |||  ||.|||  .|..|.||.   . .. . .||||.|... 
kegakpenkeknryknilPfDhtrvilk...epsvpgsdyinanyikke

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 827-874 8.5e-06 20.1 In-house 41-86 (325) alignment
Range on Protein: 827-874
Range on HMM: 41-86/325.0
TIGYSEENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDG
..    |||  |||||.  .| .|..| |    |  . .||||||.  
kvamkpenkaknrfknvvaldksrvvletkk..ddpssdyinasylrd

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 831-962 5.3e-08 26.7 In-house 158-280 (302) alignment
Range on Protein: 831-962
Range on HMM: 158-280/302.0
SEENKPFNRFKNITVYDdnriILATNPNLDMCQREYINASYVDGYSSNGIVREPHTILQVIDDVIHRQQKigggpVVVHCSDTVSRSGVYCSVSIALEQC
 .. . |   |....|     .  .| .  . ..  ..  .  ..   |  .|..| |...      ...     |.||||  | |.|   ..   .. |
ktdleeftdkksfklyt....veiknekkkkkvkktvdilafsawpdhGapkeaytaldilkfcesykkn.....vlvhcsaGvGrtGtlvaikyGiqlc

KAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSI
. . | |. .. . .|. . ||| . .| . .
skkkvtdllsivlpvrqcryGavqdeqqliyl

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 831-877 8.4e-06 20.2 In-house 6-50 (250) alignment
Range on Protein: 831-877
Range on HMM: 6-50/250.0
SEENKPFNRFKNITVYDDNRIILATNPNLDMCqrEYINASYVDGYSS
  .||  ||. .|  .|  |..| ..   . .  .|||||...||. 
kpqnkeknryadiialdssrvvLekekgdkes..dyinasflhgyde

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 832-878 1.2e-07 26.1 In-house 44-88 (318) alignment
Range on Protein: 832-878
Range on HMM: 44-88/318.0
EENKPFNRFKNITVYDDNRIILATNPnlDMCQREYINASYVDGYSSN
. ||  ||. ||. ||. |. | .    .  . .||||.|.||| ..
pvnkaknryanilaydhtrvkLqmle..geegsDyinanyidGyrrk

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 832-878 7.4e-06 20.5 In-house 59-103 (319) alignment
Range on Protein: 832-878
Range on HMM: 59-103/319.0
EENKPFNRFKNITVYDDNRIILATNpnLDMCQREYINASYVDGYSSN
..||  ||. ||  .| |.. |       .   .|||||.|.|| ..
dqnkdknriinilafdknvvklerl..iGeefsdyinasfvtGyqrk

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 832-878 9.7e-06 20.3 In-house 23-67 (284) alignment
Range on Protein: 832-878
Range on HMM: 23-67/284.0
EENKPFNRFKNITVYDDNRIILATNpnLDMCQREYINASYVDGYSSN
..||  ||. .|  .| |.. |       .   .|||||.. || ..
dqnkdknrighilafdknvvklerl..iGeefsdyinasfitGyqrk

0041856 (Phosphotyrosine protein) phosphatases II 834-971 9.5e-16 53.4 In-house 1-172 (182) alignment
Range on Protein: 834-971
Range on HMM: 1-172/182.0
NKPFNRFKNITVYDDNRiilatnpnldmcQREYINASYVDGYSSN-------------------------------------------------------
|.. ||...|  || .|               ||||....|.  .                                                       
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwp

--GIVRePHTILQVIDDVIHrqqkiGGGPVVVHCSDTVSRSGVYCSVSIALEQckaeGvVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
  |.   ....|. |..|..      ||||.||||  |.|.|...   . ...    | |..... | .|. .||.|.|..||  ..... ....
Dhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitpnqyfflqlallelll

Y_phosphatase Protein-tyrosine phosphatase 834-877 1.6e-06 23.1 Pfam-A 1-40 (235) alignment
Range on Protein: 834-877
Range on HMM: 1-40/235.0
NKPFNRFKNITVYDDNRIILatnpN-----LDmcqreYINASYVDGYSS
||  ||.|.|..||..|. |    .      |     ||||.||.||..
nkkknRykdilpydktrvkl....kgsegpsd.....YInAnyvkgyke

Y_phosphatase Protein-tyrosine phosphatase 834-877 1.6e-06 23.1 In-house 1-40 (235) alignment
Range on Protein: 834-877
Range on HMM: 1-40/235.0
NKPFNRFKNITVYDDNRIILatnpN-----LDmcqreYINASYVDGYSS
||  ||.|.|..||..|. |    .      |     ||||.||.||..
nkkknRykdilpydktrvkl....kgsegpsd.....YInAnyvkgyke

0051429 (Phosphotyrosine protein) phosphatases II 865-971 6.7e-15 51.0 In-house 5-226 (272) alignment
Range on Protein: 865-971
Range on HMM: 5-226/272.0
EYINASYVDGYssNGIVREP--------------------------------------------------------------------------------
 ||||..|.||  .. |..                                                                                 
gyiNardvggy..grvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld

-----------------------------------HTILQVIDDVIHrqqkigGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVD--------VFQV
                                   ...|.... . .      ||||.||||  ..|.|... . . |..  .| .||        ....
yilrellltlllsagearevmhlhytdwpdhgvpqeallellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleea

TKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
 . .|.  |||| | |||  .|...  ...
veelraqrpgavqteeqylflyeallellr

0051082 (Phosphotyrosine protein) phosphatases II 865-965 9.9e-11 37.0 In-house 59-148 (151) alignment
Range on Protein: 865-965
Range on HMM: 59-148/151.0
EYINASYVDGYSSNgivrePHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQckaegvVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
|...  ..|    .       .... . ....  .. ..|||.||||  ..|.|. . . . |..      |..... . .|.. ||.|.. .|.  .. 
evlhipildwpdpg.....lplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf

V
.
a

subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 868-971 9.7e-09 29.8 In-house 161-260 (290) alignment
Range on Protein: 868-971
Range on HMM: 161-260/290.0
NASYVDGYSSNGIVREPHTILQVIDDVIhrQQkigGGPVVVHCSDTVSRSGVYCSVSIALEQCK-AEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
. | . |...  . ... |.|..|. |   ..   . ||.||| | .||| .  .. ..       .| | . .| ||.|. .  |.|. .... .  .|
tHsllkgWnklnvqedtktllsliqkvk..as...ktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagi

DMYFK
 ....
vllai

PTPc_DSPc_SM00012 874-966 1.1e-20 69.2 In-house 9-103 (105) alignment
Range on Protein: 874-966
Range on HMM: 9-103/105.0
GYSSNGIVREPHTILQVIDDVIHRQQKIG-GGPVVVHCSDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
|..  |. .|.. ||.....| . ..|.. ..|||||||. |.|.|... ..|.|.|...| . ||.||. |..|...||.|.|.|||  .|...
gwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyral

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 876-976 1.2e-32 108.0 In-house 189-289 (290) alignment
Range on Protein: 876-976
Range on HMM: 189-289/290.0
SSNGIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHST
 |.| | .|.|||.||  ... | | | ...||||||||.||.|.|.. .....|| |||.||||| |  |  ||| |.| .||  |....  |..  .|
dstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfet

Y
|
y

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 877-979 5.3e-30 99.4 In-house 185-287 (287) alignment
Range on Protein: 877-979
Range on HMM: 185-287/287.0
SNGIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTY
|.| | || ||| ||.. .. |.| | ...|||||||| ||...|.. .....|| |||.||||| |  |  |||.| | |||. |.|.. .| .  .||
stgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfety

ANF
..|
sdf

subfamily_PTPN23_pd Subfamily PTPN23 877-966 2.8e-11 37.8 In-house 183-276 (288) alignment
Range on Protein: 877-966
Range on HMM: 183-276/288.0
SNGIVREPHTILQVIDDVIH---RQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
. |.   |.|.||..| | .    .|.    |.|||||  | |.||.. |  |...  | .|..|. || . .|. .   | . ||.   |...
elGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeav

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 878-978 1.5e-68 225.7 In-house 201-301 (301) alignment
Range on Protein: 878-978
Range on HMM: 201-301/301.0
NGIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
.|.||||.|.||||||||||||||||||||||||||||||||||||||.||||||||||||||||||.||||||||||||||||||||||||..|.||||
dGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnstya

N
|
n

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 878-972 5.2e-38 125.9 In-house 191-285 (305) alignment
Range on Protein: 878-972
Range on HMM: 191-285/305.0
NGIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKL
.|..... ..|..|..| ..|.|  | |..||||..|.|.||...|.||||..|.|.|||||.|.|..|......|.||.||....|..| . . 
hGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc

subfamily_PTPRD_pd Subfamily PTPRD 878-976 1.1e-23 78.8 In-house 190-287 (564) alignment
Range on Protein: 878-976
Range on HMM: 190-287/564.0
NGIVREPHTILQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTY
.|.  .. ..|..|..| . . . . ||.|||||  | |.|... ... ||. |.|..||..|. ||.|. ..  | | |||  |...|  . .  .| 
hgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnte

subfamily_PTPN6_pd Subfamily PTPN6 878-974 6.8e-16 53.1 In-house 199-301 (306) alignment
Range on Protein: 878-974
Range on HMM: 199-301/306.0
NGIVREPHTILQVIDDVIHRQQKIG---GGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
.|. ..| ..|. ..|| ..|...     ||.|||||. . | | .  . | |.. . .|.   .|. .. | .|. . | | | .||  .| .| .| .
hgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie

LHS
 ..
tkk

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 878-974 1e-15 52.4 In-house 186-281 (315) alignment
Range on Protein: 878-974
Range on HMM: 186-281/315.0
NGIVREPHTILQVIDDVIHRqQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHS
.|. ..  ..|..| .|    ..    ...||||  | |.|| .|.   ..| | . .||||.. | .|. .|  | | |.|. |||..  ... . 
kGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrn

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 878-972 1.1e-15 51.8 In-house 185-278 (515) alignment
Range on Protein: 878-972
Range on HMM: 185-278/515.0
NGIVREPHTILQVIDDVIHRQQKIGgGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKL
.|. ..  ..|..| .|   ....   |...|||  | | ||..|.   . . |   .||||.. . ||. .|  | | |||. ||...  ... 
kGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllw

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 878-966 6.9e-11 36.8 In-house 146-235 (237) alignment
Range on Protein: 878-966
Range on HMM: 146-235/237.0
NGIVREPHTILQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.|. ..  ..|.   ..|.| ...   || ..|||  | |.|..  .   | |.| . |||...  ..|   .|  . | .||  |...|
rgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqti

subfamily_PTPN3_pd Subfamily PTPN3 878-966 7.8e-10 33.1 In-house 184-271 (280) alignment
Range on Protein: 878-966
Range on HMM: 184-271/280.0
NGIVREPHTILQVIDDViHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.|.  ... .|.... | .....    |||||||  . |.||.  . .||    |.  | . .. . .|  .   | | .||. . . |
hgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeai

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 879-977 3.8e-26 87.0 In-house 199-297 (298) alignment
Range on Protein: 879-977
Range on HMM: 199-297/298.0
GIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
|. .. ...|.....|   ||. |  ||.|.||. | ||| .. ..  ||. |.| ||||||| |..|...||||.| |||. ||...  ...  ....
gvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndei

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 879-977 6.6e-23 76.3 In-house 189-287 (318) alignment
Range on Protein: 879-977
Range on HMM: 189-287/318.0
GIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
|.  .. ..|... .| . ||| | ||.|||||  | | ||.. |.| ||. |||..|||||. | .|. ..  | | .||. ||||.  . .   |..
gvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtev

subfamily_PTPRA_pd Subfamily PTPRA 879-971 2.5e-21 70.9 In-house 205-296 (330) alignment
Range on Protein: 879-971
Range on HMM: 205-296/330.0
GIVREPHTILQVIDDVIHRQQKIGGgPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
|.  ||  .|...  | . .|. .| |.|||||  | |.| .. ..  ||. |||..||||.. | .|  .|  | |.|||. || |.  |. 
GvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyyl

DSPc_SM00195 879-971 5.5e-21 70.4 In-house 172-263 (263) alignment
Range on Protein: 879-971
Range on HMM: 172-263/263.0
GIVREPHTILQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
|.  ... .|...  | ......  ||.|||||. |.|.|......|.|.....|  ||.|.. |..| ..||.|.|||||. ||..|  |.|
gvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik

PTPc_SM00194 879-971 5.5e-21 70.4 In-house 172-263 (263) alignment
Range on Protein: 879-971
Range on HMM: 172-263/263.0
GIVREPHTILQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
|.  ... .|...  | ......  ||.|||||. |.|.|......|.|.....|  ||.|.. |..| ..||.|.|||||. ||..|  |.|
gvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyik

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 879-966 2.1e-13 45.4 In-house 163-251 (284) alignment
Range on Protein: 879-966
Range on HMM: 163-251/284.0
GIVREPHTILQVIDDVIHRQQKIGG-GPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
|    |  ...... | | ..|  .  ..|||||  | |.|||  . . |.. | |  |||... . .|. ..  |  | ||  ||  .
gvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysal

subfamily_PTPRB_pd Subfamily PTPRB 879-969 2.4e-13 44.8 In-house 193-284 (293) alignment
Range on Protein: 879-969
Range on HMM: 193-284/293.0
GIVREPHTILQVIDDVIHRQ-QKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
|.  ...|.|. .  | ... ..   .|.|||||  | |.|.. ..   |.. . | .||.| .  ..|...   | | .||  |....  .
gvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldl

0043147 (Phosphotyrosine protein) phosphatases II 879-964 5.3e-12 41.3 In-house 76-155 (172) alignment
Range on Protein: 879-964
Range on HMM: 76-155/172.0
GIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALeqckaeG-VvDVFQVTKAIRRSKPGAVTTLEQYTSIYD
. |  .  .|.... . .....  ||||.||||  |.|.|. .   . |        . ..... . .|. .||||.. .||  .|.
hgvpllellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqnpsqyrflyy

subfamily_PTPN13_pd Subfamily PTPN13 879-966 1.5e-11 39.1 In-house 180-265 (273) alignment
Range on Protein: 879-966
Range on HMM: 180-265/273.0
GIVREPHTILQVIDDVIHRQQkiGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
|. ...  .||..  | . |.    ||.|||||  . |||.. .. ..|.  . .  .|| .. . .|. . | | | .||  .| .|
gvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykai

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 879-970 2.4e-10 35.0 In-house 184-276 (281) alignment
Range on Protein: 879-970
Range on HMM: 184-276/281.0
GIVREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
|.  ... .|.  ..| . ..|    |.|.|||  | |.|.| ..  ......||   .|| .| . .|...   | |. ||. .| ..  ..
GvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 881-972 2.7e-14 47.8 In-house 174-266 (270) alignment
Range on Protein: 881-972
Range on HMM: 174-266/270.0
VREPHTILQVIDDV-IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKL
. ... .|... .|  .....  ..|..||||. | |.|.   . ||..  . .. ||| .. ...|. ..  | . |||. .| .. .| . 
slstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyaer

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 881-965 1.8e-13 45.5 In-house 201-286 (319) alignment
Range on Protein: 881-965
Range on HMM: 201-286/319.0
VREPHTILQVIDDVIHRQQKIGG-GPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDV
   |  ...... | | ..|  .  ..|||||  | |.|||  . . |.. | |  |||... . .|. ..  |  | ||  ||  
pdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysa

0049260 (Phosphotyrosine protein) phosphatases II 881-964 1.1e-11 40.1 In-house 67-144 (152) alignment
Range on Protein: 881-964
Range on HMM: 67-144/152.0
VREPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALeqckaeGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
| . . .|. . ..|.. ..  ||||.||||  |.|.|...   . |        |..... . .|. .||||.. .|.  .|.
vpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 882-975 1.1e-23 78.8 In-house 195-288 (319) alignment
Range on Protein: 882-975
Range on HMM: 195-288/319.0
REPHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHST
..  ..|... .. . ..|   ||.|||||. | | | .. ....||. | |||.|||.. . .|  ..  | . |||. ||...  . .  .|
ekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdt

Y_phosphatase Protein-tyrosine phosphatase 882-966 6.1e-21 70.3 Pfam-A 150-233 (235) alignment
Range on Protein: 882-966
Range on HMM: 150-233/235.0
REPHTILQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
..|. .|..|..| ... .   ||||||||. |.|.|......|.|||..||. |||.|. | .|...||.|..||||  .|..|
espkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai

Y_phosphatase Protein-tyrosine phosphatase 882-966 6.1e-21 70.3 In-house 150-233 (235) alignment
Range on Protein: 882-966
Range on HMM: 150-233/235.0
REPHTILQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
..|. .|..|..| ... .   ||||||||. |.|.|......|.|||..||. |||.|. | .|...||.|..||||  .|..|
espkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykai

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 882-971 8.4e-17 56.1 In-house 178-269 (274) alignment
Range on Protein: 882-971
Range on HMM: 178-269/274.0
REPHTILQVIDDVIHRQQKI--GGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
....|.|.....| . ...     .|||||||  . | |.. ..|||. | ..|.||||....  .|  . | | | |||  |. .. .| |
ddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk

subfamily_PTPN12_pd Subfamily PTPN12 882-972 4.2e-14 47.1 In-house 187-279 (290) alignment
Range on Protein: 882-972
Range on HMM: 187-279/290.0
REPHTILQVIDDVIHRQQkIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKL
. ....|..|..| ..|.     |.|||||  | | |. ... .. |. ||| .   .|||..   .|. .. .| | |||. .|  .  ... 
ssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqk

0048076 (Phosphotyrosine protein) phosphatases II 882-969 9e-11 37.1 In-house 62-142 (145) alignment
Range on Protein: 882-969
Range on HMM: 62-142/145.0
REPHTILQVIDDVIHRQQKigGGPVVVHCSDTVSRSGVYCsvsiALEQCKAEGvVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
  . ..|.... . . ...  ||||.||||  |.|.|...    |.  .. .| |..... . .|.  ||||.. .|.  .|... ..
dllellleflefieealke..ggpvlVHCsaGvgRtgtlv....aaylmlllg.vsleealelvrsqrpgavpnpgqlrflyefelel

subfamily_Ptp69D_pd Subfamily Ptp69D 883-969 6.1e-18 60.0 In-house 200-285 (307) alignment
Range on Protein: 883-969
Range on HMM: 200-285/307.0
EPHTILQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
 ....|..|. | . ...   .|.|||||  |.|||.. .... |.|.|||  ||.|...| .|. ..  |. ||||. .|  .  |
vargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldy

0048179 (Phosphotyrosine protein) phosphatases II 883-964 7.5e-10 34.2 In-house 65-139 (144) alignment
Range on Protein: 883-964
Range on HMM: 65-139/144.0
EPHTILQVIDDVIHRQQkiGGGPVVVHCSDTVSRSGVYCSVSIALeqckAEGvVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
 .. .|.... . . ..   ||||.||||  |.|.|...   . .     .| ...... . .|.  ||||.. .|.  ...
llellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrfLle

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 884-977 2e-25 84.4 In-house 156-249 (250) alignment
Range on Protein: 884-977
Range on HMM: 156-249/250.0
PHTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHSTYA
 ...|.....|   ||..| .||.|.||  |.||| .. ..  ||. | | |||||.| |..|. .|.||..|||| ..| .|  . .  . ||
atavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedya

subfamily_PTPN1_pd Subfamily PTPN1 884-963 9.6e-08 26.1 In-house 181-264 (290) alignment
Range on Protein: 884-963
Range on HMM: 181-264/290.0
PHTILQVIDDVIHRQ-QKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGV---VDVFQVTKAIRRSKPGAVTTLEQYTSIY
| . |. . .| .    .   ||.|.|||  . ||| .| |   | . ....    ||. .|  ..|. . | . | .|    |
paaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsy

subfamily_PTPRK_pd Subfamily PTPRK 885-966 1e-19 65.5 In-house 193-273 (314) alignment
Range on Protein: 885-966
Range on HMM: 193-273/314.0
HTILQVIDDVIHRQQKiGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
...|...  | . |.. . |..|||||    |.|... ..| |.  . |||||||.. |..| .|.  | | |||. |||||
tgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvi

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 885-970 2.8e-16 54.5 In-house 199-284 (297) alignment
Range on Protein: 885-970
Range on HMM: 199-284/297.0
HTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYF
...|..|..| .  ..   ||..|||.  | | ||....   . . | |  ||.|.. | .|...|  | | |||. .| ..  ..
ssllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleal

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 885-969 4e-15 50.8 In-house 198-287 (325) alignment
Range on Protein: 885-969
Range on HMM: 198-287/325.0
HT---ILQVIDDVIHRQQK--IGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
 |   |||... |  | .    . .|..||||. | |.||. |.  ||..   |  ||.|.. | .|. .|  | | .||. ||. .  .
atlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealvea

0036282 (Phosphotyrosine protein) phosphatases II 885-964 2.2e-14 49.0 In-house 87-164 (174) alignment
Range on Protein: 885-964
Range on HMM: 87-164/174.0
HtILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKaEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
  .|.... | . ... .||||.||||  |.|.|. .   . | . . |..||.... ...|. .||.|.| .||  .|.
i.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy

0044763 (Phosphotyrosine protein) phosphatases II 885-972 7.4e-10 34.2 In-house 92-173 (178) alignment
Range on Protein: 885-972
Range on HMM: 92-173/178.0
HTILQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQckaeGVvDVFQVTKAIRRSKPgAVTTLEQYTSIYDVIDMYFKL
  ... . . |.. ..  ||||.||||  |.|||. .   . ...    |. ..... . .|. .| .|.. .|.  .|..  ...| 
lehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgqlrqLyefelrllke

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 886-966 7.8e-14 46.4 In-house 196-275 (288) alignment
Range on Protein: 886-966
Range on HMM: 196-275/288.0
TILQVIDDVIHrQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
 .|.... |   ...   ||..||||. | |.|.. ..  .... ..| ..||. . . .|....  | ||.||  ||.|.
pllellrqvkv.anqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevl

0046846 (Phosphotyrosine protein) phosphatases II 886-970 1e-11 40.4 In-house 94-173 (176) alignment
Range on Protein: 886-970
Range on HMM: 94-173/176.0
TILQVIDDVIHRQQKigGGPVVVHCSDTVSRSGVYCSVSialeQCKAEGVVDVFQVTKAIRRSKP-GAVTTLEQYTSIYDVIDMYF
 .|.... .  ....  ||||.||||  ..|.|...        .. |  ..|... . .|. .| |||.| |||  .|... ...
lllellefirealke..ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyefellll

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 889-967 1.1e-16 55.7 In-house 199-276 (315) alignment
Range on Protein: 889-967
Range on HMM: 199-276/315.0
QVIDDVI-HRQQKIggGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVID
..|  |  |.....  |..|||||. | |.| .....  |.| .|| ..||... . .|. . ..| ..|||  |||.. 
nlirtvkqhhtnsv..gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydall

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 891-966 2.1e-18 61.2 In-house 187-262 (283) alignment
Range on Protein: 891-966
Range on HMM: 187-262/283.0
IDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.. ||  |..   ||.||||| .. |..|....| .... ..| |||||.| | .|  ...|| ||.||  .....
fnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelv

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 893-973 4.6e-08 27.2 In-house 200-280 (287) alignment
Range on Protein: 893-973
Range on HMM: 200-280/287.0
DVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLH
 .  ...  . ||.|||..  . |||.. .. . ... .  | ||| .|   .|  . . | .  |.  .|. .  |.|  
hielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyktn

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 895-963 2e-11 38.5 In-house 165-233 (239) alignment
Range on Protein: 895-963
Range on HMM: 165-233/239.0
IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIY
| ..   |  | |.|||  | |.| .  .   | |.| .  ||.|.  ||||  .|  | | |||  |.
itkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 895-963 2.1e-11 38.5 In-house 166-234 (239) alignment
Range on Protein: 895-963
Range on HMM: 166-234/239.0
IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIY
| ..   |  | |.|||  | |.| .  .   | |.| .  ||.|.  ||||  .|  | | |||  |.
itkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfih

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 895-966 5.2e-07 23.6 In-house 192-265 (281) alignment
Range on Protein: 895-966
Range on HMM: 192-265/281.0
IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRS-KPGAVTTLEQYTSIYDVI
| |. .    | |.|||  | |||   .| |||.  ..   . |. |.   .| . .  .| ||.||  |. |.
ilrkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvl

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 896-966 1e-14 49.2 In-house 185-255 (267) alignment
Range on Protein: 896-966
Range on HMM: 185-255/267.0
HRQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
. | . |. |.||.||| | ||| .  .   ||. | |||.|.|.  . ||  ..| | |.|.|  |....
knqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihell

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 897-966 3.7e-11 37.1 In-house 206-275 (439) alignment
Range on Protein: 897-966
Range on HMM: 206-275/439.0
RQQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
 ..|   ||||||||  | |.|   .. ||||| |.|  ||.  . | .|. .   | .| ||  ||. .
andkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynav

subfamily_PTPN9_pd Subfamily PTPN9 898-966 3.2e-12 41.1 In-house 218-286 (297) alignment
Range on Protein: 898-966
Range on HMM: 218-286/297.0
QQKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
. .. | |.|||||  . |.| .... |.|.. . .|.|||... | .|  .  .. | |||.  |  .
kghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylav

subfamily_PTPRG_pd Subfamily PTPRG 899-966 6.9e-17 55.9 In-house 216-283 (563) alignment
Range on Protein: 899-966
Range on HMM: 216-283/563.0
QKIGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
.|   ||.|||||  |.|.|.|. ..  |.| ..| .|.||.. | ||  ..  |.| |||. ..|..
nkaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdal

subfamily_CG7180_pd Subfamily CG7180 901-969 1e-20 68.6 In-house 221-289 (296) alignment
Range on Protein: 901-969
Range on HMM: 221-289/296.0
IGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMY
   |||||..|| .||||||... ..||. . |. ||||.  | .|||.|. | . |.|  ||||.  .
peegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 901-970 5.4e-06 20.2 In-house 221-289 (310) alignment
Range on Protein: 901-970
Range on HMM: 221-289/310.0
IGGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDvIDMYF
.  ||.|||||  . | .| ... ..... .    ||. .|   ...|.   . |  ||. |   . . |
vrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidr.vriif

subfamily_CG42327_pd Subfamily CG42327 902-971 4.7e-13 43.5 In-house 246-316 (319) alignment
Range on Protein: 902-971
Range on HMM: 246-316/319.0
GGGPVVVHCSDTVSRSGVYCSVSIALEQCKAE-GVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
  ||.|||||| | |.|.  .  ||... .     ||. |.   .|| .  || | |||  || |. .| |
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseyak

subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 902-975 1e-07 25.7 In-house 217-290 (302) alignment
Range on Protein: 902-975
Range on HMM: 217-290/302.0
GGGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFKLHST
.  ..|.     . | |.  .. .|.|. ...  . . .. |.||  .| || .|.||.|.| .. .|.| . |
adentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialllyikkkvt

subfamily_PTPN14_pd Subfamily PTPN14 903-971 1.4e-10 35.6 In-house 229-297 (300) alignment
Range on Protein: 903-971
Range on HMM: 229-297/300.0
GGPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
  ||.||||. | |.||   . . ..  . . ..|. .| . .|. .   | || ||. .|.|.  |.|
kPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk

subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 903-965 2.2e-09 31.8 In-house 135-199 (199) alignment
Range on Protein: 903-965
Range on HMM: 135-199/199.0
GGPVVVHCSDTVSRSGVYCSVSIALE---QCKaEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDV
  ||.|||||    .||. .. | .    . |   |||.|.|.| .|... | ...|..|  ||.|
dapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiyqv

subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 903-965 2.2e-09 31.8 In-house 134-198 (198) alignment
Range on Protein: 903-965
Range on HMM: 134-198/198.0
GGPVVVHCSDTVSRSGVYCSVSIALE---QCKaEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDV
  ||.|||||    .||. .. | .    . |   |||.|.|.| .|... | ...|..|  ||.|
dapvivhcsdgqgftgvfvaldigvrsheesk.tsvvdlfevakrlrqarcgiisslqhynfiyqv

subfamily_PTPRN_pd Subfamily PTPRN 903-964 1.1e-07 25.9 In-house 224-286 (297) alignment
Range on Protein: 903-964
Range on HMM: 224-286/297.0
GGPVVVHCSDTVSRSGVYCSVSIALEQC-KAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYD
  |.|||||| . |.|||. . . |..  |    .|.    . .|  .|| | | .|.  .. 
scpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefalt

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 903-966 2.4e-07 24.7 In-house 216-279 (290) alignment
Range on Protein: 903-966
Range on HMM: 216-279/290.0
GGPVVVHCSDTVSRSGVYCSVSIALeQCKAEG-VVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
 ||||||||  . |.| . .. ..| |.  .|  .|. .. .|.|.|. ..|    ||  . ...
sGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvqvdiqylalveil

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 903-971 9.1e-07 23.2 In-house 209-278 (307) alignment
Range on Protein: 903-971
Range on HMM: 209-278/307.0
GGPVVVHCSDTVSRSGVYCSVSIALEQ-CKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
  |||||||  | |||   ..|.  ..  . .   |. .. . .|  .. |. |  ||  .. |.  || 
tnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyfl

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 904-966 1.6e-10 35.0 In-house 170-232 (392) alignment
Range on Protein: 904-966
Range on HMM: 170-232/392.0
GPVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
 |...|||  | |.||  |.   . ..|   .||||..   ||| .|  | | |||. ||  .
hpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygav

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 905-966 4e-08 27.5 In-house 230-291 (297) alignment
Range on Protein: 905-966
Range on HMM: 230-291/297.0
PVVVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVI
...||||  | ||||     . |.. . . . ||  . . .|  ..  | ||||.. .||..
yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydav

subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 907-968 1e-07 26.2 In-house 2-63 (69) alignment
Range on Protein: 907-968
Range on HMM: 2-63/69.0
VVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDM
|||||    |.| . .. . . . |.| .||.|   . .|. .|  |    .|  |.| .  
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalve

subfamily_Sponge-PTP7_pd Subfamily Sponge-PTP7 907-971 3.5e-07 24.5 In-house 1-65 (69) alignment
Range on Protein: 907-971
Range on HMM: 1-65/69.0
VVHCSDTVSRSGVYCSVSIALEQCKAEGVVDVFQVTKAIRRSKPGAVTTLEQYTSIYDVIDMYFK
|||||    |.| . .. . . . |.| .||.|   . .|. .|  |   ..|  |.| .   .|
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealk