Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| RBD | Raf-like Ras-binding domain | 139-206 | 4.7e-23 | 67.3 | Pfam-A | 2-69 (71) | alignment | ||
Range on Protein: 139-206
Range on HMM: 2-69/71.0
LIRAHLPEGQRTIVPIRQGVTIQDALMKAMKTRNLTPNTCIVYAESPRLLIEWDTDTTQLSGKEVFVE
.||.||| .||. | .|.|.|..|||.||.|.|.|.| | |.. . . . ..|| . | |.|..||
tirvhLPnnqrsvvevrpGmtvrDaLskalkrrgLnpsacaVrlvgekkpldletdissLpgeelive
|
|||||||||
| C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | 219-265 | 3.1e-16 | 48.9 | Pfam-A | 1-51 (53) | alignment | ||
Range on Protein: 219-265
Range on HMM: 1-51/53.0
HNFVRKTFIALAFCDVCKKLL----FQGFRCETCGFRYHQRCSPRVPIQCG
|..|...| .||..|.|.| .||..|..|....|..| ..||..||
HhwvhrnfkqptfCkhCgkflwgkgkqglkCswCqllvHkkCfekvpkecg
|
|||||||||
| zf-RING-like | RING-like domain | 232-257 | 6.9e-08 | 19.9 | Pfam-A | 1-28 (43) | alignment | ||
Range on Protein: 232-257
Range on HMM: 1-28/43.0
CDVCKKLLFQGFRCET--CGFRYHQRCS
| .||.. || ||.. | ..|. |
CeqCkeiviqgvrCgnedCeiklHvdCl
|
|||||||||
| Pkinase_Tyr | Protein tyrosine kinase | 581-838 | 5.1e-61 | 195.9 | Pfam-A | 1-259 (259) | alignment | ||
Range on Protein: 581-838
Range on HMM: 1-259/259.0
IEVGERIGSGSFGTVYKGKWH-------GPVAVKKLnVSNPTEQQMQAFKNEVAVLMKTRHANILLFMGWTS-KPRLTIVTQWCDGSTLFSHIHVL-EDR
.|.|...|.|.||.|..|... ||||.| .. .|.....| .|.....|..| ||. ..| . . .| |||....| .| .... ...
lelgkklGeGafGeVvegtlkgekekkevkVavKtl.keeaeeeekeefleeakimkklkhenivkllgvctkeepllivteyvegGdLlkfLrkkekek
FEMYKIIDICRQTAQGVDYLHAKQIIHRDLKSNNIFLHDDMTVKIGDFGLATVKTRWDGNEKVRQPTGSILWMAPEVIRMEEpdpYTFYCDVYSFGVVVY
... ...... | |.|..||..|...|||| . |..|.....|||.||||| .. | .| .. . .. |||||... .. .| ||.||||...
ltledllsfalqiAkGmeyLeskklvHrdLaarNvLleenkvvkisDfGLardiekddyykkkekaklpvkWmapEslkekk...ftsksDvWsfGvllw
ELIS-GQLPYPHVqDRDQILFMVGRGFLRPDPssarKDTPKSFKQLCIKCCQFEKDDRPLFHQILADL
|... |. |||.. . ..| .. .| . | ...|.....| .|.. |...|| |.... .|
Eiftlgespypgl.sneevleklkegkrlekp....encpeelyelmkqCweeepekRptfkelvekl
|
|||||||||
| Pkinase | Protein kinase domain | 582-836 | 5.4e-61 | 195.9 | Pfam-A | 2-256 (260) | alignment | ||
Range on Protein: 582-836
Range on HMM: 2-256/260.0
EVGERIGSGSFGTVYKGKWHGP---VAVKKLNVSNPTEQQMQAFKNEVAVLMKTRHANILLFMGWT-SKPRLTIVTQWCDGSTLFSHIHvLEDRFEMYKI
|..|..||||||.|||.|... ||||.|. .. ... .. .|...| | .| ||. .... .| .| .|.....|..||.... . .... .|
elleklGsGsfGkVykakekktgkkvAvKilkkeeekskkektalrElkilkklnHpnivkllevfeekdelylvleyveggdlfdllk.kkgklseeei
IDICRQTAQGVDYLHAKQIIHRDLKSNNIFLHDDMTVKIGDFGLATVKtrWDGNEKVRQPTGSILWMAPEVIRmeEPDPYTFYCDVYSFGVVVYELISGQ
.|..|...|..||| ..|||||||..||.|... ..|| ||||| . .||... .|. .|||||.. . . || .||.|.||..|||..|.
kkialqilegleylHsngiiHrDLKpeNiLldekgelkiaDFGlakkl..eksseklttlvgtreYmAPEvll..kakeytkkvDvWslGvilyelltgk
LPYPHVQDRDQI--LFMVGRGFLRPDPSsARKDTPKSFKQLCIKCCQFEKDDRPLFHQILA
||... ...|| . .. .. |. | . .......|.|. |........|. ...||
lpfsgeseedqlelirkilkkkleedep.kssskseelkdlikkllekdpakRltaeeilk
|
|||||||||
| APH | Phosphotransferase enzyme family | 670-724 | 7.5e-06 | 14.4 | Pfam-A | 144-197 (239) | alignment | ||
Range on Protein: 670-724
Range on HMM: 144-197/239.0
DRFEMYK-IIDICRQTAQGvdyLHAKQIIHRDLKSNNIFLHDDMTVK-IGDFGLATV
...|. . ... . .. | .....|.||...|.....| .. . ||..|..
lleeleervlaalaallpg...aeppvllHgDlhpgNllvdpddgrvgviDfedagl
|
|||||||||
| Kinase-like | Kinase-like | 687-790 | 8e-09 | 23.9 | Pfam-A | 158-261 (289) | alignment | ||
Range on Protein: 687-790
Range on HMM: 158-261/289.0
GVDYLHAKQIIHRDLKSNNIFLHDDMTVKIGDFG-LATVKTRWDGnEKVRQPTGSILWMAP-EVIRMeEPDPYTFYCDVYSFGVVVYELISGQLPYPHVQ
. .|.|....| .....|..|. . |..|.|. |...... . ..| . . . .| . .. . .|. |. |.|.| . . .|| ..
laanLqarglvhgkispdnflldekggvfLggftaLvragkkvvv.sevekalaPpellaekggyts.nttkmthkldaWqlGlviysiwclrlPftlla
DRDQIL
..
eeasee
|
|||||||||
| fn3 | Fibronectin type III domain | 1165-1238 | 2.6e-08 | 27.1 | Pfam-A | 3-79 (85) | alignment | ||
Range on Protein: 1165-1238
Range on HMM: 3-79/85.0
PHYLTEVRKTNATITVGWFAFD--SSDADGYVVNITSDTGT--VQIVQVKGNSNnTITLNGLRELTTYSITVRAYQQL
|. |. |. ..|. | . . ... .|| | ...|. . ..|..... . ||.||.. |.|...|.|. .
PenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavnga
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 1373-1711 | 1.3e-103 | 342.6 | In-house | 3-342 (564) | alignment | ||
Range on Protein: 1373-1711
Range on HMM: 3-342/564.0
LPISINDLVNHIAKYS----NKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNKFIATQGPM
||....| .|.|| ||| .| .. .|. .... ..|| ||...|. || .|..|.. .. . .|||||.|||| .....||||||.
kpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegd..egsDYINAsfidgyrkrkayIAtqgPl
VNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAlMeEEKFGPFIVTLTNVANHPSFTIRSLNViIPDGSNDSHTLTQYHLTSWPDHGVPK--
.|..||||..|... ||||| .| |.| |..||| .|..| ..|||.. . ..||.... |..|.. .|.| |||||||||.
aetiedFWRmvweqnsstiVmltkleEkgkvk.chkYWPek.g.tetygeltVtleeeeeladyeirtfkl.kkkkssesreVrqFhFtsWPdhgvpesa
-PLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVfSETIIGGETEIPADKFAT
.||.| ..| |...| .|||.||||||||||||||.||. ||.. |..||| ..|..||.|| |||| .||.|.|.|. | . |.||...... .
tslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheai.lealacgntevesenlkq
KLQELKEIDSSTGCSGLQSQFELLSqvT---PDLDDATEDNAGEDLAKN
.||.|.|... |. .||. |. |. | .|.. . . ... ||
hlqkLaeveedtemtgleleFqrLa..takeieleefavatkpknkkkn
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 1373-1648 | 2.7e-77 | 254.7 | In-house | 5-283 (293) | alignment | ||
Range on Protein: 1373-1648
Range on HMM: 5-283/293.0
LPISINDLVNHIAKYS----NKFEDQYLRLY-TGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGP
||..... .|..| . .| ..| .| |.|. ... . .|. ||...| || .|. |.. . . .||||.||.||.| ..|||||||
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkd..esgsDYinanyipgynsprefiatqGP
MVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALmEEEKFGPFIVTLTNVANHPSFTIRSLNVIIpdgSNDSHTLTQYHLTSWPDHGVP--
. .|. ||||..|... |||||. | | | ||.|||. |. .| |||.. . ..||.|.. ........||| |||||||||
lpetvddfWrmvwekkssiivmltqlvekgkvk.CeeYWPade.epvlyGdikvtlvaeeeledwvirelkiek...ekeerkvrqyhftsWpdhgvPek
-KPLLSLHKQVMATW--SPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFS
|.||.. ..| . . |..||.|||||||||||||||.| |.. ..| .|||.||| .||..|. .||| .||.|.|..| .
tktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvld
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1374-1671 | 1e-108 | 358.1 | In-house | 3-303 (305) | alignment | ||
Range on Protein: 1374-1671
Range on HMM: 3-303/305.0
PISINDLVNHI----AKYSNKFEDQYLRLYTGnDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYmcEREYINASYIDGYSSSNKFIATQGPMV
.|...|| ..| .. ....| || ||. . .. || ...|| ||...||..||.|||||....| ...||||||.|||....|.|..|||.
iialddlaayikearvysdkgleaqykslyee.eesidvgkkeankaknrlkeitlldddriiltekesld..dsdyinasyvdgykrkkkyivaqgPlk
NTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPK---
||.|||||||..|.. .|||||. .| |.| |.|||| . |...||.|.|.|.. .. . ...| |.. | |....|.|..||.||.|||||||.
ntvadfWrliveekvstivmltklveggkdk.CrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfat
PLLSLHKQVMATWSPSEG-PILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFAT
|||| |.|. ... ..| |.||||||||||||.|||.|||||.. .|.|||.......||..|||||||||||||||||. | |. |.|.| . .
sllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdald.elitcgdtsiigsnlra
KLQELK
... ||
rvnklk
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 1374-1647 | 1.9e-85 | 282.1 | In-house | 4-283 (288) | alignment | ||
Range on Protein: 1374-1647
Range on HMM: 4-283/288.0
PISINDLVNHIAKY----SNKFEDQYLRLYTGN-DRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPM
.||...|.... |. ....... .|. . |....... ||. ||.. | ||..|..|.. .. . . |||||||||| ...||||||||.
eisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldg..vegsdYinAsyidgynlkrkfIatqgPl
VNTLADFWRLIWQERPMHIVMLTDPKEcIKNKWCEQYWPRalMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPD---GSNDSHTLTQYHLTSWPDHGVP
||..||||..|... .|||||.. | ... |.|||| . ...|.. |||... ....|.| | | | |.. |.| |..| |.|||||||
pntvedFWrmvweqnvrvIvmltklve.lgrekcaqYwpl..ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvp
K---PLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
.||.. ..|. ....||..|||||||||||||||.|..||| ..||.||. ..|.|||.||. ||||..||.|...|..
dspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyeall
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 1374-1647 | 1.2e-83 | 276.3 | In-house | 25-296 (308) | alignment | ||
Range on Protein: 1374-1647
Range on HMM: 25-296/308.0
PISINDLVNHIAK--YSNKFEDQYLRLYTGN-DRPCTVGYTDENKYLNRFQQITVYDDNRIILtpnpnlYmCEREYINASYIDGY--SSSNKFIATQGPM
..|. ||.... | . ..| .. .|. .....|.. ||| .||. | || .|..| . ||||||.||| ...||||||||.
klsvldllkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl......d.egsdYInAsyvdgyssklprkfIatqgPl
VNTLADFWRLIWQERPMHIVMLTDPKEcIKNKWCEQYWPRALM-EEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSnDSHTLTQYHLTSWPDHGVP--
||..||||..|... .|||||.. | . . |.|||| | . ...|.| |||... .....|.| | . ... .|.|.|..| |.|||||||
pntvedFwrmvweqnvrvIvmLtklve.ngrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdg.esrtvthfhytnWpdhgvPps
-KPLLSLHKQVMATWspSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
..||.. ..| . ..|||.|||||||||||||||.|..||| ..|| ||. ..|..||.||. ||||..||.||..|..
peilldflelvrksl..pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyrall
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1374-1686 | 1.7e-79 | 262.2 | In-house | 4-318 (319) | alignment | ||
Range on Protein: 1374-1686
Range on HMM: 4-318/319.0
PISINDLVNHIAKY----SNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMV
.| ...| ... .. ....| .. | .... . ..||| ||.|.| || |..|.. .. . . .|||||.|||| .||||||.|.
eievqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldg..vegsdyinasfidgyqerekfiatqaPle
NTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMeeEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPK---
||. ||||..|.|. . .||||. .| .| | ...|||.. . |..| .|||| . . . || |.. . . .. ...... |.||||.||.
ntiedfWrmvWeeessivvmltklveklkvk.lkkywpeenf..eeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekat
PLLSLHKQVMATWSP-SEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFAT
|| | |.. ... ..||| ||||||||||||||..|..||. .|||.|. .|.||| || |||. .|| |...|. | . |.||| ... .
slldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyeall.eaveagdteievqdlrd
KLQELKEIDSSTGCSGLQSQF
.|..|.| .. || .||. .|
rlkqlaekvadtgetgleref
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1374-1687 | 5.7e-71 | 234.0 | In-house | 5-315 (315) | alignment | ||
Range on Protein: 1374-1687
Range on HMM: 5-315/315.0
PISINDLVNHIAK----YSNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMV
|| ...|. ..|. | |...| . |. .| | ||| ||. .| || |. | | . .|.||..||||. ...||.||| |
pipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllen..dphsdyvnanfidGynkkrryiaaqgpnv
NTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAlmeEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDgsnDSHTLTQYHLTSWPDHGVPK---
... |||||...| .|||||. | |.| .|.||| . .|.. ||. . . .|.|.| |. | . ... |.|.||||| ||||
asvkdfwrlvfeedigkivmltnlvegekrk.aekywpdk...kviyGkitvtrkseevnteytvrtlsvvfgd...nirevvqlhytswpdmgvpkyti
PLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFATK
||. |...|. | |.|.||||||||||||||..| |.||. | ..|. .....||.|.||||...|| |..||.. ||.. |.| | | . .
plmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydall.etfvcgdtsiaqdlylqr
LQELKEIDSSTGCSGLQSQFE
. | || . || |||
ydsllapspdtgstllqeqfe
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1374-1456 | 3.9e-07 | 23.7 | In-house | 5-87 (440) | alignment | ||
Range on Protein: 1374-1456
Range on HMM: 5-87/440.0
PISINDLVNHI--AKYSNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYS
|| . |..... . | |||.. | .| .|. . .|| ||...| .|| .|..| . . .|||||||.|
piivadfadyvqnnrrsrafedewsllpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevkg..vpdsdyinasyingie
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1375-1687 | 4e-82 | 270.8 | In-house | 2-316 (318) | alignment | ||
Range on Protein: 1375-1687
Range on HMM: 2-316/318.0
ISINDLVNHIAKYSN----KFEDQYLRLYTGNDRPCTV-GYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMV
||..|| .|... . ... .| || .. . .. .. ||. ||.. |. ||. |. |.. . . .||||.||||| .....||.|.|.
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmleg..eegsDyinanyidGyrrkkayiaaqaPlp
NTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAlmEEEKFGPFIVTLTNVANHPSFTIRSLNVIIpDGSNDSHTLTQYHLTSWPDHGVPK---
.|. ||||..|. . |||||. .| |.| ...||| . ...| |.|.. . ....|...| .....| . ||| |||||.|||.
etieDfWrmvWeqnsavivmltqeeergkak.vhryWPsk..gsrsygklvvelkeevelsdyvlrefkvtr.teeeesrqvrqyhytsWpdegvpesga
PLLSLHKQVMATW-SPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVfSETIIGGETEIPADKFAT
||.| .|| .. ....|||.|||||||||||.|||.|| ||.. |..||. ..|..||.|| |||| |||.|..|.. | .. |.||. |.....
slldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvl.lealasgdtevdasdlrs
KLQELKEIDSSTGCSGLQSQFE
...||.| |. .| . .. .|.
rirelreqdpesgttemdaefq
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 1375-1687 | 3.2e-74 | 244.6 | In-house | 4-313 (314) | alignment | ||
Range on Protein: 1375-1687
Range on HMM: 4-313/314.0
ISINDLVNHIAKYSN----KFEDQYLRLYTGndrpCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMVN
| ..||...||. | ..| |. | . |||. ||...| || |..|.. . . .||||..||.| ...||.||||. .
irvadllqsiallkraegygfkeeyeslfeg....wdaakkdenreknrsgdilaydrsrvflitidg..dpssdyinaalidsykrpaafivtqgPlqe
TLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRalmEEEKFGPFIVTLTNVANHPSFTIRSLNVII-PDGSNDSHTLTQYHLTSWPDHGVPK---
|..|||||...|. |||||. .| . | | .||| . |..|.. |.| .. . . .| ..| | .. ... |.. ..||||.||.
tvkdfWrlvydencasivmltelvevgrvk.ClkyWPe...dtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsat
PLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFATK
||.| ..| .. ...|.|.|||||| ||||||||||| |. ..||||||. .| ||.... ||.| .||.|..|... |. . ||| ||. .| .
gllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvil.eaclcgetaipvsefkal
LQELKEIDSSTGCSGLQSQFE
| ...|. | | |. .|.
ylesirldpqtnssqlkeefq
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1375-1687 | 7.2e-60 | 197.8 | In-house | 5-324 (325) | alignment | ||
Range on Protein: 1375-1687
Range on HMM: 5-324/325.0
ISINDLVNHIAKYSNKFEDQYL----RLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMVN
|.. .||.|. | . .| . | . . .| ||| |||. . .| .|..| . . .||||||. . . |.|.| |. .
iavvnlvehvekkkaqdqdgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkd..dpssdyinasylrddkkkdvflaaqaPlta
TLADFWRLI--WQerpMHIVMLTDPKECiKNKWCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSnDSHTLTQYHLTSWPDHGVPKP-
|. |.|||. |. .|.... . ... | .|||. . . .||.. | | . . . | |.| ... .. .. |..| ||.| ||.|
tindlWrlvldWr...csvvvvlneldl.gkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkG.etrsvkqfqlqswddmGvqkrp
--LLSLHKQV------MATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVfSETIIGGETEIP
|.|. . | . . . . .||||||||||||||.||.. ||.. | ||| | |..||..| .||.| |||.....|. |... |.|..|
atlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyeal.veaymsgntdvp
ADKFATKLQELKEIDSSTGCSGLQSQFE
| .|| |.| . | .. .||
vssfeaklsslqernpltqklniekefe
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 1376-1664 | 5.4e-71 | 234.5 | In-house | 2-300 (563) | alignment | ||
Range on Protein: 1376-1664
Range on HMM: 2-300/563.0
SINDLVNHIAK-YSN---KFEDQYL---RLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMCErEYINASYIDGYSSSNKFIATQGPM
......|.|. ... .|. .. . . .| ... ||| || .|. || |. |.| |. .||||.||||| |..|||||||.
pvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkkl.DYinAnyidGyqkskafiatqgpl
VNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRalMEEEKFGPFIVTLTNVANHPSFTIRSLNV---IIPDGS--NDSHTLTQYHLTSWPDHG
.|. ||||.||... |||.|. .| ..| |..|||. | |..| . |||.. . . |.|.| . .. ... .. .. .||| |.|||||
kdtfddFWrmiWeqnvaiivmitnlvergrrk.cdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhg
VPK---PLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPA
||. | |. |. |. |||.||||||||||||.|..| |.| .| .|.. |.. ..| || .||| .||.|||||. |.| ..|||. |
vPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdall.eaiasketella
DKFA
..
eqve
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 1376-1611 | 1.1e-31 | 105.1 | In-house | 9-257 (418) | alignment | ||
Range on Protein: 1376-1611
Range on HMM: 9-257/418.0
SINDLVNHIaKYSNKFEDQYlRLYTGNDRPC--TVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYsSSNKFIATQGPMVNTLA
|| .| ||| | | .... || . | . | | ||. .| . |. | . .|||| |||| ..||.||||. ||.|
siynlknhi.kcihkikeef.rlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqd..kegsdyinanyidga.ypkqfictqgplpntia
DFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEE---------EKFGPFIVTLTNVANHPSFTIRSLNVIIPDgSNDSHTLTQYHLTSWPDHGV
||||..|..| ||||. | . | |..||| . | | || . | | .| . | | . |. . ... .|||. |||| .
dfwrmvwenrcriivmlsresencrik.cdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltf.egetrditqyqyegwpdhni
PK---PLLSLHKQV------MATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQAD
| |. | . . . | . ||.||||||||||||| . | ... |
pdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkkld
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1378-1646 | 1.3e-115 | 380.3 | In-house | 4-289 (301) | alignment | ||
Range on Protein: 1378-1646
Range on HMM: 4-289/301.0
NDLVNHIAKYSNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWR
.. ....||.|||||.|| .|..|.|..||||...|||.||||..|||||||||||.|.|||..|.|||||||||||||...||||.|||| .||.||||
dlgthvaakhsnkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWr
LIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSN--------------DSHTLTQYHLTSWPDHG
|||||.|..|||.|. ||..|.| ||||||.. .|.|.|||| |||.| ...|.|.||.|||.| |||| .|....|...|.||..|
liwqekpvsivmvtnlkegtksk.ceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdG
V----PKPLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
| | ............. ||..||||..|.|.|......|.|||. .|||||. ......|......|.||.||....|..
vvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvi
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1381-1647 | 4.6e-83 | 273.4 | In-house | 12-280 (290) | alignment | ||
Range on Protein: 1381-1647
Range on HMM: 12-280/290.0
VNHIAKYSNKFEDQYLRLYTG-NDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLI
.|. || ..|..|. .| .| .. ||| | .|| ||||..| |||||||.| | .. |. |||||.||.||. ....||||||. |||.|||.||
anghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkli
WQERPMHIVMLTDPKECIKnKWCEQYWPRAlmEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHG-VPKP---LLSLHKQV
|||. |||||. .| | . | |||| . . ...|.| ..|.| .. ....| |.| . .......|||..|.|...| |..| ||......
wqekvtiivmltniieegk.vkCqqYWpds..dtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemy
MATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
. . ...|.||||..|||...|.|........ |||.|. .....|.|....||| .|| .... |.
ktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivl
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 1381-1649 | 3e-51 | 168.8 | In-house | 9-289 (296) | alignment | ||
Range on Protein: 1381-1649
Range on HMM: 9-289/296.0
VNHIAKYSNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYmcEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIW
|.. |. ... .. . . | |. ||. || .. || ||..|. . .||||.|.|.. ...| |..|. .|. .||||..
vdkrrkfrveyklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGee..ksdYinavyvdsflkkkeyivteapkketvdefWrlvy
QERPMHIVMLTDPKECIKnkWCEQYWPRALmeEEKFGPFIVTLTNVANHPSFTIRSLNVIIP---------DGSNDSHTLTQYHLTSWPD-HGVPKP---
.| .|.||.. . | . .||| .|..|...| .... . . ..|| . . . . . ......|| |. . ||
deeisavvvLtktfdfak..mypsywpnks..keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstna
LLSLHKQVMA---TW--SPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSE
|. | ..| | |||..|..| |..|.| ..|||..||....|. ||. . | .||..| ..|.. ..| .. | .
lielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 1382-1646 | 5e-80 | 264.8 | In-house | 20-300 (307) | alignment | ||
Range on Protein: 1382-1646
Range on HMM: 20-300/307.0
NHIAKYSNKFEDQYLRLYTGND---RPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLyMCEREYINASYI--------DGYSSSNKFIATQGPMVN
... .... .. .|. .. ...... ||| .||.. | ||..|..|.. .. . . ||||||. ||| ...||||||||. .
lllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgs.ledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe
TLADFWRLIWQERPMHIVMLTDPKECiKNKWCEQYWPRAlMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVP---KP
|..||||..|... .|||||...|. ... | |||| || .|.| |||... ....|.| |.| ||.. |.|.|..| |.||||||| ..
tvedFwrmlweqgvtvivmltelvel.grekcaqywPde.geeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfee
LLSLHKQVMA--TWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGV---VDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
||.. ..|.. ..|..||.||||||||||||||||....|.| ..||. ||. .|..||.||...||...||.||..|.
lldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeal
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 1382-1646 | 9.9e-80 | 263.2 | In-house | 9-273 (278) | alignment | ||
Range on Protein: 1382-1646
Range on HMM: 9-273/278.0
NH----IAKYSNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWR
.. ... ... .. .|.. . ...... ||| .||. | || .|..|.. .. ||||||.|||. ..||||||||. .|..||||
kallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllgg..dldsdYinAsyvdgynvprkfiatqgPlpetvedFwr
LIWQERPMHIVMLTDPKEcIKNKWCEQYWPralMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIpDGSNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQ
..|... .|||||...| ... | |||| . ...|.| |||... .. .|.| |.| |.. |.| |.|| ..||||||| ..||.. |.
mvwelgvttivmLtelve.lgrvkcaqYwp...ggsltygdftvtllkeehlddytvrtlevtn.lgdgesrtvthyhylgwpdhgvpeslsllldflka
VMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
|. ..|.||.||||||||||||||||....|||...|| ||. .|..||.||...|||..||.||..|.
vrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1382-1697 | 6.8e-69 | 227.3 | In-house | 15-322 (515) | alignment | ||
Range on Protein: 1382-1697
Range on HMM: 15-322/515.0
NHIAKYSNKFEDqylrLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTP-NPNlymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIW
.| . .|..| | | | | || . | ||.. | || .|..| | | . .|.||||| .. . . .||.||| .. |||||..
rhttlfseefhd....lpgpniypqtvaqeeinfkknryknilPydsvrvklevindn...PhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvl
QERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDgsnDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMA
||.. |.|.|. || | | | .||| . ||| . | | . ..| |.|. | ||.|.||.|.| |||.|||| || | |.| |
qenvttiamvtklkegdkik.cgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgd...dsrtvtqfhfteWPdkGvpkhtssllklikevka
TWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFATKLQELKEIDSST
. . |...|||||||||| .|.|| . .| .||. .|. .||.|...||| .|| |...|| | . .| || .|. .||.|.
dhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavl.edllwrntlipvihftdhlqdlhssgdgr
GCSGLQSQFELLSQVTPDLD
| | . .|. | ..||
grskmtkefqtlkslcpdpp
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1382-1687 | 1.6e-67 | 222.6 | In-house | 16-313 (315) | alignment | ||
Range on Protein: 1382-1687
Range on HMM: 16-313/315.0
NHIAKYSNKFEDqylrLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQ
| | .|..| | | . . .|. ...| ||.. | .| .|..| . ...||||||| .. . . .||.||| .. ||||...|
rhtalfseefhd....lpdPdiyrqrvaretinfkknryknilPldsarvklevidd..sPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlq
ERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLnviIPDGSNDSHTLTQYHLTSWPDHGVPKP---LLSLHKQVMAT
|.. |||.|. .| | | | |||| . .|| . |.| .. ..| | . |..|.|.||...| |||.||.| || | |.| |
ekvttivmvtkkqegdkik.crqywPdrkadsvefGsikvellsleadtdgvarkl...vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkad
WSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFATKLQELKEIDSSTG
. | ..|||||||||||| .|.|| ..|. |. .||. .|. ||..|...||| ..| |..||| | . .| |. .|. .||.|. . .|
ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavl.edllwrntlilvihftdhlqdlhtsvdgsg
CSGLQSQFE
| . .||
rskmtkefe
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1384-1648 | 2.6e-79 | 261.2 | In-house | 15-276 (287) | alignment | ||
Range on Protein: 1384-1648
Range on HMM: 15-276/287.0
IAKYSNKFEDQYLRLYT--GNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTpnpnlyMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQ
|| .. |..|. | .. |.. . .|| .||..|| |.|..|..| .. .||||..||||.....||....||.||. .||.||..
hakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk......gehpdyinavfidgykekkafiiaesPmfntarnfWklidd
ERPMHIVMLTDPKECiKNKWCEQYWPRALMeeEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHG-VPKP---LLSLHKQVMA
... ||||.. || ... | |||| .|.. ..|.| . ....| |.|. . ..| ....||..|.|...| |..| || ..... .
rnvtaivmlcqeken.deevcyqyWpeeks..vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemykt
TWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFS
.....|.||||..|||...|.|..........|||.|. .... |.|....||| .|| |. |.|
qrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivle
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 1384-1686 | 4.7e-74 | 244.2 | In-house | 27-330 (330) | alignment | ||
Range on Protein: 1384-1686
Range on HMM: 27-330/330.0
IAKYSNKFEDQYLRLYTGN-DRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQE
.| ...| ... | .|. . . . .||| ||. .| || .|.||.. | .|||||.|||| .||||.||| .|. ||||.||.
saddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGv..eesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweq
RPMHIVMLTDPKECIKNKwCEQYWPRALMeeEKFGPFIVTLTNVANHPSFTIRSLNVI-IPDGS--NDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVM
. . |||||. || ..| |.|||| . .| |.. .. ..|.| . | .||.. ..| ..|.|.||||| ||| . .|.| |.|
ksativmltelkerkeek.caqywPdeGl..vtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvk
ATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFATKLQELKEIDSS
.. | ||| ||||||||||||||..| ||. |..||. ..|.|||.|| .||||. ||.|.. .. | . |.||. . . ..||.|.. ..
klnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvll.eyylygdteldvsslekhlqklynkitg
TGCSGLQSQF
| ||. .|
tdkigleeef
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1385-1647 | 9.9e-73 | 239.7 | In-house | 17-276 (288) | alignment | ||
Range on Protein: 1385-1647
Range on HMM: 17-276/288.0
AKYSNKFEDQYLRL-YTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQER
|. . |...| | .... |.| .|. ||...| || .|. |. .. . .|||||||||. ...|.||||||. .|. |||.|.....
arnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkklee..eagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenk
PMHIVMLTDPKECIKNKwCEQYWPRAlMEEEKFGPFIVTLTNVANHPSFTIRSLNVIipdGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWS
|||||. | |.| ||.||| | .....| . |||... . .|. |.| . ... ..|||. ..|||||||. ||| | .|| . .
tstivmltelveggktk.CeeYWPda.dkpknyGsvtvtlveskeledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllellrqvkvanq
PSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|||.|||||||||||||||.| .... ..| ..|.||.|..||.||. .|||| ||.|.....
adtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1385-1663 | 2.5e-60 | 199.1 | In-house | 22-296 (297) | alignment | ||
Range on Protein: 1385-1663
Range on HMM: 22-296/297.0
AKYSNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSsnKFIATQGPMVNTLADFWRLIWQERP
. .. |....| | . | .| || | .|.. | || .|..| . . .|.|||.. |. ..|.|| || .|.||||.....|..
nrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnd..dpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqv
MHIVMLTDPKEciKNKWCEQYWPRALMEEekFGPFIVTLTNVANHPSFTIRSLNVIIPDgSNDSHTLTQYHLTSWPDHGVPK-----PLLSLHKQVMATW
||||.| .| ..| | .||. . . || |.|. |.. | |.|.| . . . . ||. ..|||. |.. || | ..| ..
stivmlnddne..rdkkcaryWsdkgvtt..fGdvsvvllsvsereGfikrelevtkgk.akarrvvkqyqfveWPdkaverkdsassllklisevrkdf
SP-SEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKF
| .|||.||||.||||||| ...|| . .| || ||| |.|..|||.|...||| .|| |.. || |... .|.|.|. |
sqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavl.eallsedtriqasyf
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1385-1672 | 1.3e-50 | 166.9 | In-house | 16-257 (392) | alignment | ||
Range on Protein: 1385-1672
Range on HMM: 16-257/392.0
AKYSNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERP
..| | ... | . | ||. .. |. ||...| || .|..| . . ...|.|||||... . . .||.||| . .| ||||...||..
nrhsalffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvklevidd..ipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenv
MHIVMLTDPKECIknkwceqywpralmeeekfgpfivtltnvanhpsftirslnviipdGSNDSHTLTQYHLTSWPDHGVPKP---LLSLHKQVMATWSP
|.|.|. || .| .| .|.|.| |||..||| || . |.| | .
ttiamvtklkegd..............................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGq
SEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFATKLQELKE
|...|||||||||| |.|| . .| . .||. .| .|..| |||| .|| |.. ||. | .. .| || .|. .||.|.
ythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavl.edllwrntlipvvhftdhlqdlst
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 1386-1687 | 7.6e-85 | 280.3 | In-house | 15-312 (317) | alignment | ||
Range on Protein: 1386-1687
Range on HMM: 15-312/317.0
KYSNKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPM
. ....... .|.. . ...|.. ||| .||. | ||..|..|.| .. . ||||||.||.. ..||||||||. ||..||||..|...
sdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplgg..dldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvt
HIVMLTDPKEcIKNKWCEQYWPRalMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPdGSNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATWSPS
.|||||...| ... |.|||| |. ..|.|.|||... ....|.| | | |...|.|.|..| |.||||||| ..||.. ..| . ...
vivmLtelee.lgrekcaqYwpl..getltygdftvtllseeelagitlrtlevedl.gdsesrtvthfhytgWpdhgvppspdllldfleavrealedp
EGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSETiIGGETEIPADKFATKLQELKEIDSSTGCSGL
.||.||||||||||||||||....||| ..|| ||. .|..||.||...|||..||.||.||.. ..| .|| ....||..|.... .. ..
ggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl.krkltlepaselklkllklliplalddvklk
QSQFE
.....
ekelk
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 1386-1647 | 1.5e-78 | 259.6 | In-house | 29-286 (297) | alignment | ||
Range on Protein: 1386-1647
Range on HMM: 29-286/297.0
KYSNKFEDQYLRLYTGNDrPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMcEREYINASYIDGYSS-SNKFIATQGPMVNTLADFWRLIWQERP
. ..... .. .|. .. ...... ||| .||.. | ||..|..|.|... .. . ||||||.|||. ..||||||||. .|..||||..|...
nsktllllefeellslkp.dysiallpenkdknrykdilpydhsrvklkpedgvdl.dsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgv
MHIVMLTDPKECIKnkWCEQYWPRALMeeeKFGPFIVTLTNVANHPSFTIRSLNVIIpdgSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWS-
.|||||...|. . |.|||| ..|.| |||..| .. .|.| |.| .. |.|.|... |.||||||| ||.. ..|. .
tvivmLtklvelgr..kcaqywpeegg...tygdftvtllkvehldgytvrtlevtn...ngesrtvthfqytgwpdhgvppslellleflelvrealae
-PSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|..||.||||||||||||||||....||| ..|| ||. .|..||.||...|||..||.||.||..
lpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydall
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 1388-1649 | 7.6e-47 | 154.4 | In-house | 28-291 (297) | alignment | ||
Range on Protein: 1388-1649
Range on HMM: 28-291/297.0
SNKFEDQ--YLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYID-GYSSSNKFIATQGPMVNTLADFWRLIWQERP
...| . | | ... ..|. ...| || ... ||..|. |. . . . .||||| | . .||||||. .|.||||...|..
kdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeas..aeksdyinasaildhdprapayiatqgplastvadfwqmvweqGv
MHIVMLTDPKECiKNKWCEQYWPRAlmEEEKFGPFIVTLTN-VANHPSFTIRSLNVIIPDgSNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATWS
. ||.|| .| | |..||| .| .. . | | . .||. . . .... |.||.| |||..||| |.|| . ..| ..
vvivnltrleee.gvkqckrywpde..Gsevyhiyevhlvsehiwcddylvrsfylknlq.tsetrtvtqfhflswpeegvPasaksllefrrkvnksyr
PSEGPILVHCSAGVGRTGTFIAIDIALEQADRE-GVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSE
||.||||.|.||||..|.||. |.. . .||| .. ||.|| ..|.| ||. | || |
GrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 1389-1670 | 1.6e-71 | 235.9 | In-house | 22-305 (307) | alignment | ||
Range on Protein: 1389-1670
Range on HMM: 22-305/307.0
NKFEDQYLRLY-TGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYmcEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHI
.. | .| . |. ..|. .||. ||...|. .|..|..|.. . . .|||||.| || ..|||| |.|. .|. ||||.|.. |
fglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingke..dsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtli
VMLTDPKECIKNKwCEQYWPRAlmEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPD----GSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWS
|||.. .| ..| |..||| .| ..| .|.| . .|. ..||.|.| . .||. ..||| |.|.| ||. || | .|| .
vmlsnlteknrkk.cakYWpie..devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyk
PSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFATKLQEL
...||.|||||||||.|.|.|.|. |.| | ||| .| ||.|| .|| |.|||||. |. ... |.|.. |... ....|
lnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyrall.dyssygdtdedvddledaierl
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1389-1647 | 6.5e-69 | 227.4 | In-house | 27-287 (298) | alignment | ||
Range on Protein: 1389-1647
Range on HMM: 27-287/298.0
NKFEDQYLRLYTGND----RPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPnlYMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERP
...... || .... .|. ..||| ||...| .| |..|. . | .|||||....|. .| |||||.|...|..||||....|
tgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLeked..adeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedi
MHIVMLTDPKECIKNKwCEQYWPRAlmEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSnDSHTLTQYHLTSWPDHGVPKP---LLSLHKQVMAtWSP
|||||. .| | | ...||| ..|..| . |.| . .. ...| |.| . . ..... | | |||||.|||. .| | ..| | .
gtiVmltnleeldktk.yhkywPde..gketygeitvsllskeefadlivrklkvskkkee.kerevrqlhftsWpdkgvpenatsvldllrkvra.sqq
SEG--PILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
| |..|.|||||||.||||||| ||.. .| |||. .|..||..|...||| .||||...||
qagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavl
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1389-1647 | 2.2e-67 | 222.2 | In-house | 15-273 (281) | alignment | ||
Range on Protein: 1389-1647
Range on HMM: 15-273/281.0
NKFEDQYLRLYT-GNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMCerEYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHI
. | .| |. |.| . | ..|||. ||.. |. || |. .||| . .. .||||....||.. ...||||||. ..|..||...|... |
aGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenknt..DYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsai
VMLTDPKECIKNKwCEQYWPrALMEEEKFGPFIVTLTNVANHPSFTIRSLNViiPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWSPS-E
||.| | | | | .||| .| |.| ..|. |. ...... | ... |... ...| . |.|||||||. ||. .|.|. . ... .
vmvtreieagklk.ChrYWP.ddnselkygdvtvkstaeeekatyierkfkl..eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktk
GPILVHCSAGVGRTGTFIAIDIALEQADRE-GVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|...|||||||||||.||.| .......| .|. .|. ||..|. ||||. || |.. ||
aplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavl
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1389-1647 | 8.3e-38 | 125.1 | In-house | 16-274 (307) | alignment | ||
Range on Protein: 1389-1647
Range on HMM: 16-274/307.0
NKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPnlymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIV
... |.. | . || . | ||.|.. . | .||... . .|| | |. .|||..|||. || .|| .. ||. ..
qalvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdg....lasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvi
MLTDPKECIKNKwCEQYWPRALMEEEKFG--PFIVTLTNVANH-PSFTIRSLNV--IIPDGSNDSHTLTQYHLTSWPDHGVPKPLLSLHKQVMATWSpSE
|| . | | | |||||| .. || | ....|. . . .|| . | ...| |.... . |||.|||. |. . |. .
mlckvielakik.ceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry.dt
GPILVHCSAGVGRTGTFIAIDIALEQ-ADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|..|||||||||.|| .|| . .. . . |. .|. ||.|| .|| ||..|| ..
npvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvll
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1389-1466 | 3.2e-09 | 30.9 | In-house | 23-95 (95) | alignment | ||
Range on Protein: 1389-1466
Range on HMM: 23-95/95.0
NKFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNpnlymCEREYINASYIDGYSSSNKFIATQG
..|.... . | ||| .. | ||| .| || |..|| . . .|||| ..|||. | .||.||
qefdnefksismtsgapytvgsseanipknrflnifpydatrvvlttk.....rdsdyinacfvdgyarkncyiaaqg
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1390-1658 | 2e-62 | 205.6 | In-house | 9-273 (283) | alignment | ||
Range on Protein: 1390-1658
Range on HMM: 9-273/283.0
KFEDQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlymcerEYINASYID---GYSSSNKFIATQGPMVNTLADFWRLIWQERPMH
| . |. . |..... .|||| ||.|.| ..| .|. | .... .||||..| | ..|.|..|.|. .| |||.....|.
klfrevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesr......dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekita
IVMLTDPKECIKNKwCEQYWPRAlmEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPKPLLSL--HKQVMAT-WSPSE
||||| .| . | | ||||. |..|.| ||| . . ||.|. | . .... |. | . | . | .. || .|.. .
ivmltklqedlrik.CsqyWPkr..GsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskk
GPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSETIIgGETEI
|||.||||.|.|||..|||. ....| | |||. .|. .|.||| .||||||| ..|..|. ... |.|.|
gPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalc.gdtqi
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 1391-1647 | 2.7e-83 | 274.9 | In-house | 2-271 (284) | alignment | ||
Range on Protein: 1391-1647
Range on HMM: 2-271/284.0
FEDQYLRLYTGNDR---PCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlYMCEREYINASYIDGY-----SSSNKFIATQGPMVNTLADFWRLIWQE
.|... .|. . ...|.. ||. .||...| .||..|..|.. .. . . .||||||.||| ...||||||||. ||..||||..|..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldg.dledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
RPMHIVMLTDPKEcIKNKWCEQYWPRAlMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATW
. .|||||.. | ... |.|||| | ..|.|.|||... .....|.| | . . .. |.|.|..| ||||||||| ..||.. ..|
nvrvIVmltelve.ngrekcaqYwple.gevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrell
S--PSEGPILVHCSAGVGRTGTFIAIDIALEQADREG---VVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
. |..|||.|||||||||||||||.|..||| ..|| .||. ..|.|||.||. |||||.||.|...|..
enlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyeall
|
|||||||||
| DSPc_SM00195 | 1391-1647 | 3.3e-80 | 264.6 | In-house | 2-259 (263) | alignment | |||
Range on Protein: 1391-1647
Range on HMM: 2-259/263.0
FEDQYLRLYTGN-DRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVM
.. .. .| . . ....| . ..|| ||...| .||..|..|..... . .||||.||.|.....|.||||||. .|..||||..|.|. |||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
LTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVANHP-SFTIRSLNVIIPDGsNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATWSPSEGP
||...|. |.| |..|||. ..|.|| . |.|..| ... ....| |.. . ......|||. ..||||||| |..|.| ..| . | |.||
lteeeengkek.cdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgp
ILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|.|||||||||||||..|||.|.. ..| ||| ||..||.||..|||||.|| |...|.
ivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeail
|
|||||||||
| PTPc_SM00194 | 1391-1647 | 3.3e-80 | 264.6 | In-house | 2-259 (263) | alignment | |||
Range on Protein: 1391-1647
Range on HMM: 2-259/263.0
FEDQYLRLYTGN-DRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVM
.. .. .| . . ....| . ..|| ||...| .||..|..|..... . .||||.||.|.....|.||||||. .|..||||..|.|. |||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekk..egsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivm
LTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVANHP-SFTIRSLNVIIPDGsNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATWSPSEGP
||...|. |.| |..|||. ..|.|| . |.|..| ... ....| |.. . ......|||. ..||||||| |..|.| ..| . | |.||
lteeeengkek.cdrywpeesggketfgkisvklvevekkkdeiilrtleltkegk.eetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgp
ILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|.|||||||||||||..|||.|.. ..| ||| ||..||.||..|||||.|| |...|.
ivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeail
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1392-1494 | 4e-10 | 33.7 | In-house | 17-120 (347) | alignment | ||
Range on Protein: 1392-1494
Range on HMM: 17-120/347.0
EDQYLRLYTGNDrpCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMC---EREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIV
|. | |. .. .|. . . || .. . |. |..|.|. |||||.| .|...| || |. .|. |||... . .|
fdenlanyspsk..ftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvv
MLTDPK
. .|.
tifepi
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1393-1646 | 4.8e-31 | 102.5 | In-house | 31-286 (310) | alignment | ||
Range on Protein: 1393-1646
Range on HMM: 31-286/310.0
DQYLRLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYmceREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTD
|| .| . .| | .. . ||. .. . |. |. |. . | .|| | |. . || .|||. |. ||||.|.||| |..|
kqyrkldakqdssltyeaykkymhknrysdvvcldtsrvklkidksry...edyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllck
PKECIKNKwCEQYWPrALMEEEKFGPFIVTltNVAN-HPSFTIRSLNV-IIPDGSN---DSHTLT-----QYHLTSWPDHGVPKPLLSLHKQVMATwSPS
| . | | ||| .| | .| || |... | | | | ..|| . | . ||| ||| | . .
vgeegrpk.cvgywp.slgvtetygcirvt..nlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvpqrlla.qvr
EGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
|| .||||||..|... .|........|| ||. .. |...|.. .|| ||....
hgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvr
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 1394-1647 | 1.2e-58 | 193.3 | In-house | 20-272 (280) | alignment | ||
Range on Protein: 1394-1647
Range on HMM: 20-272/280.0
QYLRLYTG-NDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlymcerEYINASY----IDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIV
|. .|| ... ... || ||.. |. ||. |..|. ... .||||.| |.. . .|..||||||. .| .|||...|... ||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklkeset......dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssliv
MLTDPKECIKNKwCEQYWPRaLMEEEKFGPFIVTLTNVANHPSFTIRSLNViIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWSPSEGP
|||. | . | | ||||. .| ..| | |.... ... |. .| | . ........| ..|||||||. .|.. ..| .. | .| |
mlttlverGrvk.ChqyWPe.tedeleygefsvkcekedetksyvlrelvl.kdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeeP
ILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
..||||||.|||| .|....|| ... | . || ..|.||. .||| .|| |. .|..
vvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeail
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 1397-1647 | 1.4e-71 | 236.4 | In-house | 16-269 (278) | alignment | ||
Range on Protein: 1397-1647
Range on HMM: 16-269/278.0
RLYTGNDRPCTVGYTDENKYLNRFQQITVYDDNRIIltpnpnlymcerEYINASYIDGYssSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKEC
| .|. .|.. .|...||. .| || .|.. .|||||||||| ..||||||||. .|.|||||..|... .|||||. .|
llllgipseitpalylgnldknRykdilpydhsrVk............dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvel
IKNkWCEQYWPRalMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIP---DGSNDSHTLTQYHLTSWPDHGVP-----KPLLSLHKQVMATWS--------
.. |.|||| .. . .|.| |||... ... .|.| |.|. . .. |...|..|...||||||| |..|.| ... . .
gre.kcaqywpe..ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllasllls
-----PSEGPILVHCSAGVGRTGTFIAIDIALEQAdrEGVVDIAGIVNRLRQQRMK-MVQTLDQYVFLHDAVF
.|.||.|||||||||||||..|... ||. ||.||. .|. ||.||. .||.|.||.||....
slllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefll
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 1400-1647 | 6.2e-64 | 210.7 | In-house | 26-274 (290) | alignment | ||
Range on Protein: 1400-1647
Range on HMM: 26-274/290.0
TGNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYmcEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKN
. . . ..| ..||. ||.. | || .|. |. . . . .||||..| | ... ..||.|||. .|| ||||.||. . .||. | |.
aekvysteagekeenvkknrykDilPydksrvelskieeee..gsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkk
KwCEQYWPRALMEEEKFGPFIVTLTNVANHP-SFTIRSLNVIIPdgsNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATWSPSEGPILVHCSAGVG
| ||.||| || .||.| |||.. . |.||.|.| ..|....|.| |.||||||| |.||.| ..| . . .. |..||||||||
k.CerYWpeegeeelefgefevtleeekavdddflirtLkveaq...kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvG
RTGTFIAIDIALEQADREGV---VDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|||| ||||.. |. .| . .|. .| .||.|| .||| .||.... ||
rtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykava
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 1401-1661 | 6.5e-34 | 112.0 | In-house | 27-283 (307) | alignment | ||
Range on Protein: 1401-1661
Range on HMM: 27-283/307.0
GNDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMCerEYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECiknK
.. . | ..|.|. | ... | |. | . |. ..| | ...| |.|| .| |. || ||||...||. .||||| || .
vdeislttaasdnnlekarskrvhckdssrvklelrrGqyld..dfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes...e
WCEQYWPRALMEEEKF--GPFIVTLTNVA--NHPSFTIRSLNVIIPDgsN--DSHTLTQYHLTSWPDhgVPKPLLSLHKQVMAtwspsEGPILVHCSAGV
|| |||.| . .. | . .. .| | |.. |... .| . |. . | | || | | . |..|.. ||
rceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgd..deerflehwqgdvnnssd..vysplrvlrklrnl.....skpvvvqdilGv
GRTGTFIAIDIALEQADREGVV--DIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF--SETIIGGETEIPAD
...|..||.||| . | .. . | ||..| |.. .|.|.. | .|| |. |
skaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvigsakeldvd
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 1402-1647 | 1.2e-81 | 269.6 | In-house | 27-274 (297) | alignment | ||
Range on Protein: 1402-1647
Range on HMM: 27-274/297.0
NDRPCTVGYTDENKYLNRFQQITVYDDNRIILtpnPNlymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECiKNKW
.. ...|. ||. .||. | ||..|..| .. . ||||||.|||. ..||||||||. ||..||||..|... .|||||.. | .
llgslsvallpenleknRykdilpydhtRVkl...dd...egsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvel.grek
CEQYWPRALMEEEKFGPFIVTLTNVAN--HPSFTIRSLNVIIPdGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMA--TWSPSEGPILVHCSAGV
|.|||| |. ..|.|.|||..| ....|.| | | |...|.|.|..| |.||||||| .||.. ..| .||.||.||||||||
caqywpleegesltygdftvtllsvevvllddytlrtlevtdt.gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGv
GRTGTFIAIDIALEQAD---REGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
||.|||||.|..|.| . .|| ||| .|. ||.||. .||||.||.||..|..
gRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeall
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 1402-1647 | 2.8e-80 | 265.0 | In-house | 26-269 (273) | alignment | ||
Range on Protein: 1402-1647
Range on HMM: 26-269/273.0
NDRPCTVGYTDENKYLNRFQQITVYDDNRIILtpnpnlYMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKEcIKNKW
.. ...|.. ||| .||.. | ||..|..| . . ||||||.||| ...||||||||. ||..||||..|... .|||||.. | ...
plltysvallpenkdknrykdilpydhsrvkl......gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelve.lgrek
CEQYWPRALME-EEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNdSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATWSP--SEGPILVHCSAGVG
|.|||| | ....|.|.|||... .....|.| | . . .. |.| |..| |.||||||| ..||.. ..|. . . |.||..||||||||
caqYwpleggelsltygkftvtllseetkddytvrtleltnlgtge.srtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvg
RTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|||||||.|..|.| .|| ||. .|..||.||. ||||..||.||..|..
RtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyeall
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 1402-1652 | 1.3e-47 | 157.0 | In-house | 20-274 (290) | alignment | ||
Range on Protein: 1402-1652
Range on HMM: 20-274/290.0
NDRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlymcerEYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKw
.| |... ..||. |||.. .. || ||.| . | .||||| .. ..| ||||..|| . ||...|... .||| | ..|
sdfptreaklpenrnlnryrdvspydhsrikleradn......dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqik.
CEQYWPRALM-EEEKFG--PFIVTLTNVANHPSFTIRSLNVIiPDGSNDSHTLTQYHLTSWPDHGVPKP---LLSLHKQVMA--TWSPSEGPILVHCSAG
| ||||. .| .. . |.| . .. .|.| |.. ..........| |.||| |||. .|.. .| . |. || ..|||||
caqywPqgeeekellledtklkvkliseerksyytvrllele.nlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaG
VGRTGTFIAIDIALEQADREGV---VDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSET-II
.||.|||. .| | . .... ||| . ||..|. ..|| || | . |. . .|
iGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvi
|
|||||||||
| subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 1402-1680 | 1.2e-09 | 31.3 | In-house | 54-339 (346) | alignment | ||
Range on Protein: 1402-1680
Range on HMM: 54-339/346.0
NDRPCTVGYTDENKYLNRFQQITV--YDDNRIILTPNPNLYMCEREYIN--ASYIDGYSSSNKFIATQGPMVN---TLADFWRLIWQERpMHIVMLTDPK
| | | .. ||| . | . . | |. | |.. |. . .|.| .| | .. . ||| .|.||. .|.| | |
nregcpkiydenrvqlnrpghedvnyinasvitlkdvsrrmacvpayvhlvvlyfvifqfehklivaqlpqmenesfvedfwymiyqeq.ihlvylmvpd
ECIKNKWCEQYWPRALMEEEKFGPFIVT-LTNVANHPS-FTIRslnvIIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWSPSEGPILVH
. .|| . . || ..|. | .|| ..|.| || .| . | | |.. . .| .. . . |
dklkntttslfndenggyqytgkmfinnrradvsgdpkeytie....vlpegnsdsvicqvhhhapwkhlqqppktlpiikmihqflsekqvqnagvcvv
CSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSET--IIGGEtEIPADKFAT-KLQELKEIdsSTGCS
| ||. .|| |..| . .| |. ..||| |... || .. || || . | .| ..|| || | ||
slfgcgracsfigalyainqlnngiepniceimknikqqrpggvesfaqyasiyaivfdyiarkrggk.kapvnkdinrfidelaei..spacs
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 1403-1648 | 4.6e-53 | 174.9 | In-house | 34-278 (288) | alignment | ||
Range on Protein: 1403-1648
Range on HMM: 34-278/288.0
DRPCTVgyTDENKYLNRFQQITVYDDNRIILTpnpnlyMCEREYINASYIDGYSS-SNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKw
.| ... . ||.. | || ||. | . .|||||.. . |. . .|||||.|. .||.|||....... ||||....| |.|
krsiai..aklyseknrsrdilPyDhnRvklr......gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpk.
CEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDgSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMA----TWSPSEGPILVHCSAGV
...||| . | .|||.. ||| .| . . . | |.. . | .. .... .|||||..|||. || . ..| . . .|. |..|||||||
vdrYwPedkgetvkfgdlsvtlksvretethvervlkletld.adavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGv
GRTGTFIAIDIAL-EQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFS
||||.| . |. | ..|..|| .|.|||.|| |||. .|. |. .||
gRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavle
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1403-1646 | 7.4e-43 | 141.5 | In-house | 22-255 (267) | alignment | ||
Range on Protein: 1403-1646
Range on HMM: 22-255/267.0
DRPCTVGYTDENKYLNRFQQITVYDDNRIILTPNpnlymcEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDpkECIKNkwC
.. .. .|. ||... |||.|.|| . |.|||||||..|| |.||.||.|. || .||. .| ... ||.|| . |
sstisqsiaeknqernrlddnlpyddtrvilrtk......eeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltk..vftdn..i
EQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSndSHTLTQYHLTSWPDHGVPKPLLSLHKQVMATWSP--SEGPILVHCSAGVGRTGTF
..|| . . .|. . | . . . | .|.. . . | .| .| |. | || | ..| . |..|.||.||||.|||
rlfwPPkmgqakkyqdltvehslekeendyqiitlelkfknes..ahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtf
IAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
. || ||.| .|||.|| . ..|.||. .|.|...|...|. .
lvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihell
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 1403-1646 | 1.9e-39 | 131.6 | In-house | 35-276 (314) | alignment | ||
Range on Protein: 1403-1646
Range on HMM: 35-276/314.0
DRPCTVGYTDENKYLNRFQQITVYDdNRIILtPNPNLYMCEreYINASYIDGYsssNKFIATQGPMVNTLADF----------WRLI--WQERPMHIVM-
. ..|.. .|. ||...| .| || || |. . . . ||||||.||. .||||||||. .|. || ||.. .. .. |||
eltilvadlflnrdknryldilpad.nrvil.pglpvsgsd..yinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivms
--------------------LTDPKECIkNKWCEQYWPRALmeeekfgpfivtlT-------NvanhpsftirslnviipdgsndSHTLTQYHLTSWPDH
|... . | ....... . ... .|. . .||.
rdevladelsrLdaAlgKtpllildgng.neptaadlellk.............eelydpelf......................erlgikylripvpDg
GVP--KPLLSLHKQVMATwsPSEGPILVHCSAGVGRTGTFIAIDIALEQAdreGVvDIAGIVNRLRQQRM-----KMVQTLDQYVFLHDAV
..| . .... . . . . .||.||||.||.||||||..... . . || ... .....|..|. ....|.||.| ..|.
saplledfdeflefieea..dkggpvlvHCkaGkgRtgtfvvaaylmkll...gv.sleealedvrlkRpinpnpgfieqleqyefileal
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 1405-1646 | 2.9e-73 | 241.8 | In-house | 2-242 (249) | alignment | ||
Range on Protein: 1405-1646
Range on HMM: 2-242/249.0
PCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMCEreYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECiKNKWCEQ
...|.. ||| .||.. | || .|..|.. |.|. . |||||||||| ....|||||||. .|..||||..|... .|||||...|. ... |.|
eysvallpenkdknrypdilpydhsrvklsilpglflsd..yinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvel.grekcaq
YWPRalMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPdGSNDSHTLTQYHLTSWPDHGVPKPLLSLHKQVMATWS-----PSEGPILVHCSAGVGRTGT
||| .. ..| | |||..| ....|.| | . . ..|.| .... |.|||||||. . .| . . | .. |..||.|||||||||||||
ywpl..ggsleygdftvtllsvevkddytvrtleltnl.ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGt
FIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
|||....||| ..|. ||. .|. ||.||...||...||.||..|.
fiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeal
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 1405-1647 | 4.9e-57 | 188.3 | In-house | 28-266 (273) | alignment | ||
Range on Protein: 1405-1647
Range on HMM: 28-266/273.0
PCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNlymcereYINASYIDGYSSSNKF--IATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwC
|.|| ..||| ||.... ||. |..| . . |||||.| ... ||.|||. .| .|||...|. . |.|.| || | | |
tcevgkkkenkdknryrnvlPydetrvklgdegg.......yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvk.c
EQYWPRALMEEEKFGP-FIVTLTNVANHPSFTIRSLNVIiPDGSNDSHTLTQYHLTSWPDHGVPKPLLSLHKQ--VMATWSPSEGPILVHCSAGVGRTGT
..||| .. | . |.| .| .. .|..|.|.|. |..|. ... ....|||||||. ..| . ... ..|||.||||||.||.||
hrywPesknkklkvsnrlevellkvqkldgfvvralavk.dsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGt
FIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
.|.||..|. .|. .|. ||..||.|| .||| |||.| . |.
litidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykail
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 1405-1646 | 1.7e-48 | 160.1 | In-house | 40-292 (300) | alignment | ||
Range on Protein: 1405-1646
Range on HMM: 40-292/300.0
PCTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLymcEREYINASYIDGYSSS--NKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwC
.... .||. |||... |.|||. |.|. . . .||||| | .. ..|..|||. .|. |||...|.. |||||. .| |.| .
llstaklpenaeknrfkdvlPyednrvelsptken...stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkek.s
EQYWPRA--LMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDgSNDSHTLTQYHLTSWPDHGVPK---PLLSL-------HKQVMATWS--PSEGPILV
.|.|. .. .|| | || . . .|.. ..|.. |.. |. | |||||||. . || ... . . |. |.||
fkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlp.skeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlv
HCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
|||||||||| | |. .. . . ..|| ...|||.||| .|||| || |.....
hCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvl
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1405-1653 | 9.8e-36 | 118.2 | In-house | 26-272 (285) | alignment | ||
Range on Protein: 1405-1653
Range on HMM: 26-272/285.0
PCTVGYTDENKYLNRFQQITVYDDNRIILTpnpNlymCEREYINASYIDGYS-SSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCE
|| . | |||. .. . .. |..| | .|.|| ||.. . .|.||||. .||.|||..|.||. ...|| | .| |
nctytayeanpdlnryadvrcieetrvvlk...n...hdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvek.ca
QYWPRALMEEEKFGPFIVTLTNVANHP-SFT-IRSLNVII-PDGSNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMAtWSPSEGPILVHCSAGVGRT
|.| | | ||| . .|||.. . . | . .| || | |.. . . .. |||. | .|.. |.| | | | || ||||||||||
lyypeklgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkk.vnpkekpicvhcsagvgrt
GTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHdAVFSETIIG
||. || | . . ... || .| |.. ||. |..||. |. | .||
atfvgidyatirimenpniemldivremramrfqavqshmqflfly.vvlmeyfig
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 1406-1646 | 3.5e-70 | 231.5 | In-house | 1-239 (245) | alignment | ||
Range on Protein: 1406-1646
Range on HMM: 1-239/245.0
CTVGYTDENKYLNRFQQITVYDDNRIILTPNPNLYMCEreYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQY
..|.. ||| .||. .| ||..|..|.| .. . . ||||||.||| ..||||||||. .|..||||..|... .|||||.. | ..| |.||
ysvallpenkdknrysdilpydhtrvklspdggdldsd..yinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvk.caqy
WPRalMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIpDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWS-PSEGPILVHCSAGVGRTGTFI
|| |. ..| |.|||... .....|.| |.| .|.. |.. ..|| ..||||||| ||.... | . .|.||.|||||||||||||||
wpl..gesltygdftvtllseehlddytvrtlevtn.lgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfi
AIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
|....|||...|. |.. .| .||.||...|||..||.||..|.
aaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 1406-1646 | 1.4e-65 | 216.6 | In-house | 2-238 (243) | alignment | ||
Range on Protein: 1406-1646
Range on HMM: 2-238/243.0
CTVGYTDENKYLNRFQQITVYDDNRIILtpnpnlymCEREYINASYIDGYsssNKFIATQGPMVNTLAD----FWRLIWQERPMHIVMLTDPKECiKNKW
.... ||. ||.. | ||..|..| ||||..|... ...||||||. .|..| |||..|... .|||||...| . .
fsiallpenlsknrysdilpydhsrvkl........egsdyinanliyvt...prliatqgPlpetveddlasfwrmlwelgitvivmltelvEl.grek
CEQYWPralmEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMAT--------WSPSEGPILVHC
|.|||| .|. .|.|.|||... .....|.| | . .| .. ... ..|| ..||||||| .||.....| . .|.||.||||
caqywp....gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHC
SAGVGRTGTFIAIDIALEQAdreGvVDIAGIVNRLRQQRMK-MVQTLDQYVFLHDAV
|||||||||.||... |.. | ||. .|..||.||. .|||..||.||..|.
saGvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeal
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1406-1645 | 2.7e-33 | 109.8 | In-house | 29-264 (281) | alignment | ||
Range on Protein: 1406-1645
Range on HMM: 29-264/281.0
CTVGYTDENKYLNRFQQITVYDDNRIILTP-NPNLYmcEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQ
||| |. ||. .| . | |. | || .|| | || .| |||| .| |||||.|||| |||| . | ..| | .
ctvfnqpvnnkknrylnipcldisrvqlkvkmpnkn..stdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrek.cae
YWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIpDGsnDSHTLTQYHLTSWPDHGVPKPLLSLHKQVMATWSPSEgPILVHCSAGVGRTGTFIAID
|.|| .| . |. . . |. ||. .| ... .|.. ||| ||. . | . . | | ..||||||||.||..|..
yfprnahcclqfdklsvsyedstvnkslvttrlnlsy.eg..etrlithwlwkewpdwqvpessevmlkilrkirarst.ppvihcsagvgrsgtlmave
IALEQADRE-GVVDIAGIVNRLRQ-QRMKMVQTLDQYVFLHDA
|||. . || || .|| | ||||.||...
ialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkv
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1408-1670 | 1.9e-67 | 222.9 | In-house | 55-310 (319) | alignment | ||
Range on Protein: 1408-1670
Range on HMM: 55-310/319.0
VGYTDENKYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTdpkecikNKWCEQYWP
|.|| ||. .| .| |.. | . .|||||...|| . .|.||.|||. ||||||||.||. . ||.|| .. | ||||
fanldqnkdknriinilafdknvvklerliGe..efsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt.......kdkcsqywp
RALMeeEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWS--PSEGPILVHCSAGVGRTGTFIA
.| . | | .. | . ...|.... .| .||.|. |||.|||. .|. | |.| | . .|.|||||||||||..|.
lkiv..ikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyiv
IDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSETIIGgETEIPADKFATKLQEL
.|. |.. ..| ||. .|. ||||| ..|| | || |.. |. | ..| ... | . |.||
ldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfg.hsdvampdfpayleel
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 1408-1646 | 1e-64 | 213.5 | In-house | 48-293 (306) | alignment | ||
Range on Protein: 1408-1646
Range on HMM: 48-293/306.0
VGYTDENKYLNRFQQITVYDDNRIILTpNPNLYmcEREYINASYIDG--YSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQY
| ||| ||.. | .|..|.||. .|... . .||||.||.. .|....||||| . .|..||||..||| |||.| | |.| | .|
egakpenkeknryknilPfDhtrvilk.epsvp..gsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkek.CarY
WPRALMEEEkFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPKP---LLSLHKQVMATWSPSE----GPILVHCSAGVGRTG
|| . ..|| .| || .. .. ....|.|.| . ....... ||| .||||||||| .|.. ..| . . .| |||.||||||.||||
WPdeeekee.yGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtG
TFIAIDIALEQADREGV---VDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
||| ||| |.. ..|. .|| .|. .|.|| .||| .|| |.. |.
tfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykai
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1408-1648 | 1.5e-64 | 212.6 | In-house | 3-240 (250) | alignment | ||
Range on Protein: 1408-1648
Range on HMM: 3-240/250.0
VGYTDENKYLNRFQQITVYDDNRIILTPNPnlYMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNkwCEQYWP
|. .|| ||. .| .| |..| .. | .|||||...||. .. |||||||...|. ||||....| |||||. || |. ..||||
vakkpqnkeknryadiialdssrvvLekek..gdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt..yhqywP
RAlmEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDgSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWSP-SEGPILVHCSAGVGRTGTFIAI
. ||.| |.| . .. .|.| | . .|. .. |.| ..||| |||. | | |.| |. ..|..|.|||||||.|.||||
ve..kaekyGdvtvsllskeefadytkrklklskak.kaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiai
DIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFS
| ||.. .| |||. ....||..|...|..|.||||.. ..
davlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilk
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1408-1647 | 1.9e-52 | 172.9 | In-house | 14-261 (270) | alignment | ||
Range on Protein: 1408-1647
Range on HMM: 14-261/270.0
VGYTDENKYLNRFQQITVYDDNRIILTPNPNlyMCEREYINASYIDGYSSS-NKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYW
. . .| |||...| |..| . . . .|||| |. |.... .|.||..||. .|| .|||.||.|. |||.|. .| ..| ||.||
lpeaargkklnRyadiLPsPatRvrleelee..dsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkk.CerYW
PRALME--EEKFGPFIVTLTNVANHPSFTIRSLNVIiPDGsnDSHTLTQYHLTSWPDHGVPKPL---------LSLHKQVMATWSPS--EGPILVHCSAG
| | . ..| |. .. ... . .. |.. .| ... |. .. ..|||||||. |.. ..| .. . ..|.|||||||
paepkekvkledgkikvlalseekeegyiltrlrle.ekg..eerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaG
VGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
||||||.||.|||.. .... ||.. |...||..||..||. .|| ||. ||
vgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavv
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 1408-1566 | 6.8e-11 | 36.1 | In-house | 46-196 (332) | alignment | ||
Range on Protein: 1408-1566
Range on HMM: 46-196/332.0
VGYTDENKYLNrFQQITVYDDNRIILTPNpnlYMCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWP
.. |. | .| || . . ||. . . ||||| .. .|.| | . . . ||... ... ||.| . | .| ..|.|
etarleavnrn.vvkivpydrylvrltss...qlnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelklek.sdkyfp
RALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIpdgSNDSHTLTQYHLTSWPDHGVPK
|| ||| . |. . .. . | | . |..| . |.. | . .||
dktreelkfGildverkefvkrniletrllelsk...GnethrvlhykvfGwtettlpk
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1410-1670 | 1.6e-66 | 219.7 | In-house | 21-274 (284) | alignment | ||
Range on Protein: 1410-1670
Range on HMM: 21-274/284.0
YTDENKYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTdpkecikNKWCEQYWPRA
|.|| ||. .| .| |.. | . .|||||.| || . .|.||||||. ||||||||.||. . ||.|| .. | ||||
nldqnkdknrighilafdknvvklerliGe..efsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.......kdkcsqywplk
LMeeEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWS--PSEGPILVHCSAGVGRTGTFIAID
.| . | | .. | . ...|.... .| ...|.|. |||.|||. .|. | |.| | . .|.|||||||||||..|..|
iv..ikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivld
IALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSETIIGgETEIPADKFATKLQEL
. |.. ..| ||. .|. ||||| ..|| | || |.. |. | ..| ... |.. |.||
vlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfg.hsdvalpdfpayleel
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 1411-1647 | 2.2e-59 | 195.9 | In-house | 39-287 (297) | alignment | ||
Range on Protein: 1411-1647
Range on HMM: 39-287/297.0
TDENKYLNRFQQITVYDDNRIILTPNPNLYMceREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAL
. | ||.. . ||. |. |. .. . .||||...||| . |||||||. .| ||||..|... . ||| | | . | | ||||
lranleknrytdvlcydetrvvlakvdedea..sdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlk.cgqyWplee
MEEEKFGPFIVTLTNVANHPSFTIRSLNVIIpDGSNDSHTLTQYHLTSWPDHGVPKPL---LSLHKQV-----------MATW--SPSEGPILVHCSAGV
. ..|| . |. .| .. ...|.|.. ..| ..| . ..||||.|||. | . ..| ..| ||. ||.||||||.
essaefgdlsvsnveveeeedykvrvleikn.vkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGi
GRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|||||||..||.|.. ...|.||. |..||.|| ..|| .||.| . ||
GrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavl
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1411-1564 | 2.5e-10 | 34.4 | In-house | 93-235 (244) | alignment | ||
Range on Protein: 1411-1564
Range on HMM: 93-235/244.0
TDENKYLNRFQQITVYDDNRIILTPNpnlYMcEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKEciknKwcEQYWPRAL
.| . || .| ||. |. | |||||.. . ..| || |. .| |||... . .|.| .| . ..||| .
npnnswknregaglpfdfnrvplskg...sm.gntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee....e..deywpdse
MEEEKFGPFIVTLTNVANHPsfTIRSLNVIIPDGSNDSH-TLTQYHLTSWPDHGV
| ||||. . |.. |. | |.|| .|| . .. || |
plewyeeditvtltdrdefk..nikasnleiesdmneshqaltmfqisnwpsdgt
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1412-1646 | 6e-34 | 112.1 | In-house | 53-285 (305) | alignment | ||
Range on Protein: 1412-1646
Range on HMM: 53-285/305.0
DENKYLNRFQQITVYDDNRIILTpNPNlyMCerEYINASYIDGYS-SSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAL
| .. ||.|.. . | . . | .|. . .|| | |. ..||..|||. .|. .|| .. |.. .|||| | | | | |||| |
diaitknryqdvpcqdqsavkld.kps..ps..dyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklk.caqywpaaq
MEEEKFGPFIVTlTNV------ANHPSFTIRSLNVIIPDGsnDSHTLTQYHLTSWPDHGVPKPLLSLHkQVMATWSPSEGPILVHCSAGVGRTGTFIAID
| .. || || . | ||. . .. .. . . | ||| ||| |. ..... |. ||.||||||.||||| .||.
geklelksgivv.envsgskpmerdaeiqitllnltysgd..qkmsvrhlqwtewpdrgvppckltsl.ellsairgskvpivvhcsagigrtgtivaie
IALEQ-ADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
||. |. . . .|. ||.|| .|. ||.|.| .
yilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvm
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1413-1646 | 8.4e-52 | 170.7 | In-house | 2-235 (237) | alignment | ||
Range on Protein: 1413-1646
Range on HMM: 2-235/237.0
ENKYLNRFQQITVYDDNRIILTPNPNLymceREYINASYIDGYSSS-NKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAlM
||| ||. .|..|| .|..| . . .||||.|..|. . .|.||.|||. .. |||...|||. ||||| | . | | .||| .
enkiknrygnivaydhsrvvlkgagsg....sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelk.chkywpst.d
EEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMAT--WSPSEGPILVHCSAGVGRTGTFIAIDIA
. . .| . |.|. . .|.||| . .. . ||..|||||.|||. || . |... . || ..|||||||||| |. ||
qpaaygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidam
LEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
| || . |||| | . ..| ..|| |||||.|...
lrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqti
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1413-1647 | 3.7e-41 | 135.7 | In-house | 53-280 (290) | alignment | ||
Range on Protein: 1413-1647
Range on HMM: 53-280/290.0
ENK--YLNRFQQITVYDDNRIILTPNpnlymCEREYINASYIDGYSssNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAL
.| ||..... | |.|| . .|. | |..| || |||.. .| |.||.. ||. |||| . | | | ||||.|
kntefkknrykdvvcndktrvilkdG.....ydGdyvhanyvkGlk..amfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkak.ceqyypeke
MEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPKPLLSLHKQVMATwSPSEGPILVHCSAGVGRTGTFIAIDIALEQA
| || . |. .. .. . .|. . . | .| | ... ||||. |.. |.| . . . ||. ||||||.||||||.||...|.
GevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlril.rkasGpvvvhcsaGiGrtGtfvaievglqil
DREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
.|....| ||. |.. || ||. | ....
ldGkeldlldlvralrnsrlnsvqvdiqylalveill
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1413-1645 | 1.8e-27 | 90.6 | In-house | 50-280 (302) | alignment | ||
Range on Protein: 1413-1645
Range on HMM: 50-280/302.0
ENKYLNRFQQITVYDDNRIILTpnpnlyMCEREYINASYIDGYSSSNKFIATQGPMVNTL---ADFWRLIWQERPMHIVMLTDPKECIKnkWCEQYWPRA
.| |. ... ..|.|...|. ... .|.||| .. . ... | .| | |.. ..|||...||. ..|.| ..|. | ....|.
knlkknqsedvpildsnlvkle......aepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk..tlselfpkk
LMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPKPLLSLHKQVMAT---WSPSEGPILVHCSAGVGRTGTFIAIDIA
. ...| . | | . . | ..|.| .| . |.|| |... ||. .| |... .... .... |.|| |.|.. .|
sgdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlava
LEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDA
.|. ... . |. ||. .|.|| ..|..|.|||.|. |
veklqkgkepnikeivksiRsqRpravdslkQyvslyia
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1413-1499 | 1.5e-07 | 25.2 | In-house | 33-116 (332) | alignment | ||
Range on Protein: 1413-1499
Range on HMM: 33-116/332.0
ENKYLNRFQQITVYDDNRIILTPNPnlymCEREYINASYIDGYSSSNKFIATQGPMVN-TLADFWRLIWQERPMHIVMLTDPKECIKN
.| .|| .. ..| .|. |.|. . .. |||..|||| . .| .| |. . | |||.. . .| |... | | |
nnmdmnriphlycfdhsrvelapqd....gkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkr
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 1414-1647 | 6.7e-75 | 246.9 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 1414-1647
Range on HMM: 1-234/235.0
NKYLNRFQQITVYDDNRIILtpnpN----LYMcereYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECiKNKWCEQYWPRA
|| ||...|..||..|. | . ||||.|..||....||||||||. .|..||||..|||. |||||. .| ... |.||||..
nkkknRykdilpydktrvkl....kgsegpsd....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek.grekcaqYwpee
LMEEEKFGPFIVTLT-NVA-NHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAID
|....| . |.|. .. .. ..|.| |.. ..........|.|.|.||||||| |.||.| ..| . ....||..|||||||||||||.|.|
eeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvald
IALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|.|||...|. ||. ||..||.||..|||.|.||.||..|..
illeqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 1414-1647 | 6.7e-75 | 246.9 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 1414-1647
Range on HMM: 1-234/235.0
NKYLNRFQQITVYDDNRIILtpnpN----LYMcereYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECiKNKWCEQYWPRA
|| ||...|..||..|. | . ||||.|..||....||||||||. .|..||||..|||. |||||. .| ... |.||||..
nkkknRykdilpydktrvkl....kgsegpsd....YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek.grekcaqYwpee
LMEEEKFGPFIVTLT-NVA-NHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVP---KPLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAID
|....| . |.|. .. .. ..|.| |.. ..........|.|.|.||||||| |.||.| ..| . ....||..|||||||||||||.|.|
eeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvald
IALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|.|||...|. ||. ||..||.||..|||.|.||.||..|..
illeqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1414-1647 | 3e-51 | 168.9 | In-house | 7-237 (239) | alignment | ||
Range on Protein: 1414-1647
Range on HMM: 7-237/239.0
NKYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNK-FIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAlme
|| ||. .| || .|..| | .||||||. | | | .||||| . . ||||..|||| ||||| | |.| | |||| .
nkaknryanivtydhsrvvleklsnd..phsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkk.chqywpds...
EEKFGPFIVTLTNVANHPSFTIRSLnVIIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQ
|. . ||| . . ||.. |. | . . . |||.| |||.|||. .| |.... | | ..||||||||||.|. || | |
tskycnlrvtlrktevfadyiirtf.vmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrq
ADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
| .. ||| |. .|..| .|||| .||||.| ||.
akkqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1414-1647 | 3.6e-51 | 168.6 | In-house | 8-238 (239) | alignment | ||
Range on Protein: 1414-1647
Range on HMM: 8-238/239.0
NKYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNK-FIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAlme
|| ||. .| || .|..| | .||||||. | | | .||||| . . ||||..|||| ||||| | |.| | |||| .
nkaknryanivtydhsrvvleklsnd..phsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkk.chqywpds...
EEKFGPFIVTLTNVANHPSFTIRSLnVIIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQ
|. . ||| . . ||.. |. | . . . |||.| |||.|||. .| |.... | | ..||||||||||.|. || | |
tskycnlrvtlrktevfadyiirtf.vmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrq
ADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
| .. ||| |. .|..| .|||| .||||.| ||.
akkqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 1414-1649 | 3.5e-48 | 158.9 | In-house | 1-170 (182) | alignment | ||
Range on Protein: 1414-1649
Range on HMM: 1-170/182.0
NKYLNRFQQITVYDDNRiiltpnpnlymcEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTdpkeciknkwCEQYWPralmee
|. .||.. | || .| ||||....|. ...|||||||. .|.|||.|...... .||.|| .|.|||
nldknrysdilpydhsr............dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt..........eelywp......
ekfgpfivtltnvanhpsftirslnviipdgSNDSHTLTQYHLTSWPDHGVPKpLLSLHKQVMATWSpSEGPILVHCSAGVGRTGTFIAIDIALEQadre
.. .. .||. ..||||||| | .|.. . . .. ..||.|||||||||||||..|... ...
...............................ellerlgiqylylpwpDhgvpd.ldelldfieevle.eggpvlVHCsaGvgRtgtlvaaylmkkl....
GvVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSE
| |.. .|. .|..|..||.|..||.||..|.. .
g.vsleeavklvrsrRpgmvitpnqyfflqlallel
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1414-1647 | 6.6e-25 | 82.4 | In-house | 43-273 (312) | alignment | ||
Range on Protein: 1414-1647
Range on HMM: 43-273/312.0
NKYLNRFQQITVYDDNRIILTPNPNLymcereYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRA--LM
| |||. .| ..| |. |. . |. || | .. . ..|..||||. || . ||.| |..|. | .| | .| ..
fkdlnrypniqcwdrgrftlagdenf......yihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsek.cakyisdivgfv
EEEKFGPFIVTLTNV--A--NHPSFTIRSLNVIIPDGSNDSHtLTQYHLTSWPDHGVPKPLLSLHKQVMATwSPSEGPILVHCSAGVGRTGTFIAIDIAL
. | . |.. . | | |.|.. ..|. | .| .||||||.| . .. . | |.. |||||||||||.. |. .
dledhrvyteycteieiggkskdkithrvlkvvvkatgqesk.lnhyqwaswpdhgmpdscdtalrllsav.kkdkkpviahcsagvgrtgtlaliesmi
EQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
.. . ||..| . |... |||. .|.
aalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvl
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1415-1647 | 6.8e-61 | 200.7 | In-house | 29-265 (274) | alignment | ||
Range on Protein: 1415-1647
Range on HMM: 29-265/274.0
KYLNRFQQITVYDDNRIILTPNPNLyMCEREYINASYIDGYSSSN-KFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALME-
.. ||...| . |..|... . . .|||| || ||. . ..|||||..||.|||||.|.||. |||||. || ..| |..|.| |
qtknryktilPnensrvllesesse.dedssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqk.CavyfPdaedye
-EEKFGPFIVTLTNVANHPSFTIRSLNVIIpdGSNdSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATWSPS---EGPILVHCSAGVGRTGTFIAIDI
.|..| . .. ... .. ...|.| . .. ..... | |.|||| .|. .||.| ..| . . . .|..||||||.|||| ||||.|
iserygdveikvekiverndysvrklvlky..ler.ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisi
ALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
|. | ..|.|||. .|| ||..| |||| .|| ..| |.
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralc
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1415-1665 | 1.6e-57 | 189.9 | In-house | 49-293 (439) | alignment | ||
Range on Protein: 1415-1665
Range on HMM: 49-293/439.0
KYLNRFQQITVYDDNRIILTPNPNLymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKnkwceqYWPRAlmEEE
. ||..... .| |..| | . |||| ||.|| . .|||||| .| |||||..... ..|||||. | | ||| .|
qtknrykdvgafdhtrvtlqeipgv..phshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk......ywpsd..aev
KFGPFIVTLTNVANHPSFTIRSLNVII-PDGSNDSHTLTQYHLTSWPDHGVPKPLLSLHKQVM----ATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQ
.| .| . | ..|| ..|. | .. .|. |.| ..|||. || . . . | . ||..|||||||||||| ||.||||||
cygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeq
ADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFsETIIGGETEIPADKFAT
| ||| |||. ||.|| .|||.| ||||...||. | |. |.. . |.|
lklenkvdikgivkvlrkqrkqmvqalcqyvfiynavl.edivyGdiavtidefkk
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1415-1646 | 2.6e-36 | 119.9 | In-house | 49-283 (305) | alignment | ||
Range on Protein: 1415-1646
Range on HMM: 49-283/305.0
KYLNRFQQITVYDDNRIILTPNpnlymCEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPR---ALM
. ||.... |.||. | . ||| | |. . ...|| || |. .| |||| . .|.. | || . .| .| | .|.. .
agknrykdvgcldnnrvklegp.....wpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakk.cleyfaskdkdvl
EEEKFGPFIVTLTNVANHPS------FTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPKPLLSLHKqVMATWSPSEGPILVHCSAGVGRTGTFIAIDI
| |. | |. . .. . ... ..| .... |.|| ||| ||| |.. . ... || ||| ||||||.||||. . ..
efeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlaile.llekarpskgpivvhcsagigrtgsvvmley
ALEQADREGV-VDIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
|.| . | |....|.|| . .|| .||.|.|. .
ildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvi
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1416-1650 | 3.4e-32 | 106.6 | In-house | 45-271 (288) | alignment | ||
Range on Protein: 1416-1650
Range on HMM: 45-271/288.0
YLNRFQQITVYDDNRIILTPNPNLYmcereyINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEK
.|.... | |. |. .|..| |.| . ...| .| |. |. .|... .. .||||.. | |.| ..|.| | |. .
trdryenlprcditrvklsddpdfy......iaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkek.saeyfPsklGekar
FGPFIVTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPKPLLSLHKqVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGV
.| . . . ... . | ... . . || |.|.|||. || . .. . ||.||.|||||||||.| | ||||.. .
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplr.llevlkslqkPivvhssaGvGrtgtlililialeslrlddf
VDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFSET
. | ....||..|.| .|| ||...| |. |
lgirsllaklreerfkaiqtemqylyvhrcvleel
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1417-1647 | 7.2e-48 | 157.8 | In-house | 41-274 (287) | alignment | ||
Range on Protein: 1417-1647
Range on HMM: 41-274/287.0
LNRFQQITVYDDNRIILTPNPNLymcEREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRAlMEEEKF
||. .. .||.|..|. ...| .|||| |. .| ..|||.|||. |. ||||.....| ....| | ..| | .||| .
knryadvlPiddtrvllsaegel...GsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlk.cykywPer.evPmrv
GPF-IVTLTNVANHPSFTIRSLNVIIPDGsNDSHTLTQYHLTSWPDHGVPKP-------LLSLHKQVMATWSPSE-GPILVHCSAGVGRTGTFIAIDIAL
| . .| | .| ...|.| .| .. .... . |..| ||||.... |. .... .. . || ||..||...|.||.|...|. . .
GGysvvlldydikePeygvralrlidlet.rearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlv
EQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
.. | ||.| .| |||..| .||. |. .| .|.
srledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1417-1571 | 2.7e-23 | 77.3 | In-house | 36-186 (297) | alignment | ||
Range on Protein: 1417-1571
Range on HMM: 36-186/297.0
LNRFQQITVYDDNRIILTPNPnlymCEREYINASYIDG--YSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEEE
||...| .||.|. | . ||.|||| |. . |.| .|||. .|. |||.|.... |||.. .| ..| | |||.. |
knryrdilatddtrvkllrvi....terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdk.capywpsvvqerl
KFGPFIVTLTNVA--NHPSFTIRSLNVIIPdgsNDSHTLTQYHLTSWPDHGVPKPLLSL
| | ..| .. . |..| ..| .. |||||||| | |
kagdvvveflsstsdefdrviltelqliyr...sesrvvrhvqflswpdhGvpsdledl
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1417-1514 | 1.8e-15 | 51.5 | In-house | 50-158 (350) | alignment | ||
Range on Protein: 1417-1514
Range on HMM: 50-158/350.0
LNRFQQITVYDDNRIILT-----PNP-NLYMCEREYINASYIDGY------SSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQ
||...| |. .|..| .. . . .||||.|. .. |.||||.|. .|. ||...| . |..||. | .| |..
knrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlek.cyr
YWPRALMEEE
||.. ...
YWqegsyddi
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1417-1653 | 2.8e-12 | 40.9 | In-house | 50-281 (303) | alignment | ||
Range on Protein: 1417-1653
Range on HMM: 50-281/303.0
LNRFQQITVYDDNRIILTpnpnlymcEREYINASYIDgYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVM-LTDpKEcIKNKWCEQYWPRALmEEEK
||| .. . | .. |. . || |||.. ||.| | || |. | ||||..| ... ... ||| | .. . .|| . |
knrfvdvicldhskvkls........dssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlllltd.se.ydklggdsvfprnq.dflk
FGPFI---VTLTNVANHPSFTIRSLNViiPDGSNDShTLTQYHLTSWPDHGVPKP-LLSLHK------QVMATWSPSEGPILVHCSaGVGRTGTFIAIDI
| . .| .... | | .|. | | .| .|| .| . | |. .|.|. .. . | |.||.||| ..
feersirvgefkrvelgdgwvlkvlsv..sngdyks.flhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymsls.gcgragtfalfet
A-LEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDaVFSETIIG
| | . . .|. .. .|. |.. || | |. ... ...| ...
ahlslhseqasldlvkclenvrngrlhavqnlsqfsvvyt.llaehvld
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1422-1647 | 3.8e-26 | 86.9 | In-house | 26-256 (290) | alignment | ||
Range on Protein: 1422-1647
Range on HMM: 26-256/290.0
QITVYDDNRIILTPNPNLYmcEREYINASYIDgYSSSNKFIATQGPMVNT-------LADFWRLIWQERPMHIVMLTDPKECIKN-KW--CEQYWPRALM
.... ..|..| . . .|| |... ... ..|.|| | .. . .|| .. ||. ..||| . .| .| .. |..| | .
evpLveatrvvLkgygkrf..nddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvg
EEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGsnDSHTLTQYHLTSWPDHGVPKPLLSLHKQVMATWsPSEGPILVHCSAGVGRTGTFIAIDIALEQAD
|| ||. . | .. .. . .| | | |. .|.| . | .| . |.. ..| . .. |. |..||| |. | .. ||...
eelkfkgltvkCkskekeddvetRelvvkfdde..eeftvtHsllkgWnklnvqedtktllsliqkvk.asktpvivHcvdGiSrsAalaaiilgyQkia
-REGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
.| | .. ... ||.|| ..... .. | ...
etsgsvkledvlkalrkqralaitsalelafvdagiv
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 1426-1644 | 6.9e-32 | 105.9 | In-house | 2-165 (178) | alignment | ||
Range on Protein: 1426-1644
Range on HMM: 2-165/178.0
YDDNRIILTPNPNLYMceREYINASYIDGYsssnKFIATQGPmvntlADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMeeekfgpfivtltn
.|..| .|.. ..| . .|||||.|... ......| ||...|.... |||.||...|. ..| | .|||.
ldrtrvllsnlegler..sdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflk.cdpywpeeag..............
vanhpsftirslnviipdgsndshtlTQYHLTSWPDHGVPK---PLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQadreGVvDIAGIV
||. . .|||||| .| ... . . ....||.||||||||||.||..|... ... |. .. ..
..........................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeai
NRLRQQRMkMVQTLDQYVFLHD
...|..|. .|.. .|. .|..
elvrerRp.ivpnpgqlrqLye
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1443-1571 | 1.4e-20 | 68.2 | In-house | 55-186 (319) | alignment | ||
Range on Protein: 1443-1571
Range on HMM: 55-186/319.0
EREYINASYIDGYSS-SNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECiKNKWCEQYWPR--ALMEEEKFGPFIVTLTNVANHPSFTIRSLNV
. ||..|||. || . | .||.| .. .. .||||..|. . || |||. | | | .|.| .| ... .| . ||| . . . . | .| .
kdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlsel.GikvcaeylPtketldntslyGdilvtlkgrevkdryaistlll
IIPDGSnDSHTLTQYHLtSWPDHGVPK---PLLSL
|.. | || | |.. .|| .|...
krvdke.esrelthywy.kwleaevPaeeaaliam
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1443-1564 | 1.9e-07 | 25.5 | In-house | 12-126 (130) | alignment | ||
Range on Protein: 1443-1564
Range on HMM: 12-126/130.0
EREYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWqERPMHIVMLTDPKECIknkwcEQYWPRALMEEEKFGPFIVTLTNvaNHPSFTIRSLNVIIP
. .|||||.. ..... || |. .| |||... || . .... | ..||| . | |||||. . . |.. |. |
gntyinasfvGllgrtaeylltqhpladtsmdfwkmml.eryvnvlvvlgsveee.....deywpdsePlewyeediivtltd..rdefknikasnleie
DGSNDSH-TLTQYHLTSWPDHGV
. |.|| .|| .... || |
sdlneshqaltmfqisnwpsdgt
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 1444-1643 | 1.4e-42 | 140.7 | In-house | 5-154 (172) | alignment | ||
Range on Protein: 1444-1643
Range on HMM: 5-154/172.0
REYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPkeciknkwceqywpralmeeekfgpfivtltnvanhpsftirslnviIPD
. ||||||.|.| ..|||||||. ||||||||..... |||.||. |
sdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...............................................lyd
GSNDSHTLTQYHLTSWPDHGVPkPLLSLHKQVMATWS----PSEGPILVHCSAGVGRTGTFIAIDIALeqadreG-VvDIAGIVNRLRQQRMKMVQTLDQ
... ... ||. ..||||||| .| | . . . ..||.|||||||||||||..|... | . .. .|. .|..|...||. .|
pellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqnpsq
YVFLH
| ||.
yrfly
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1444-1641 | 5.3e-34 | 112.3 | In-house | 75-272 (301) | alignment | ||
Range on Protein: 1444-1641
Range on HMM: 75-272/301.0
REYINASYIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVAN--HPSFTIRSLNVII
| | | .|. ...|||||||. || ||| .. | .||||. | ..| ||.| | |. . | | ....| . . . |.|.|
rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleek.ceeylpvkisekldigrfkikiknkelilnkkiskrtleved
PDGSNDSHTLTQYHLTSWPDHGVPKPLLSLHkQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVF
| ...|.| | ..|.|.|||| |. ..| || ||.||||||.||. .||. .. . . . .... ...||..| . ||| | .
stgkfatrtvthyqysewtdrgvPkshaelf.dlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlyw
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1444-1507 | 5.9e-09 | 29.7 | In-house | 90-154 (349) | alignment | ||
Range on Protein: 1444-1507
Range on HMM: 90-154/349.0
REYINASYID--GYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKWcEQYWP
.|||| |. .| .|.|||| |. |. ||...| .. .. |.| || .|. ..||
ddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc.diywq
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 1445-1648 | 7.7e-52 | 171.9 | In-house | 5-223 (272) | alignment | ||
Range on Protein: 1445-1648
Range on HMM: 5-223/272.0
EYINASYIDGYSS---SNKFIATQGPMVNTLADFWRLiWQERPMHIVMLTDPKECIKNKwCEQYWP----------RALMEEEKFGPFIVTLTNVANHPS
||||....|| . .......||. .| |||||| .... .||.|... |. ..| |..||| .. .| . |||. . ...
gyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlk.cdrywpgirylhlpilddsaptilygalrvtllseellld
FTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVP-KPLLSLHKQVMAtwspsEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVD--------IAGIV
...| | ... . .........| |.||||||| ..||.| ... . .||.|||||||..||||..|... |.. ..| .|| ....|
yilrellltlllsagearevmhlhytdwpdhgvpqeallellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeav
NRLRQQRMKMVQTLDQYVFLHDAVFS
..||.||...||| .||.||..|.
eelraqrpgavqteeqylflyealle
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 1445-1644 | 6e-43 | 141.9 | In-house | 3-164 (174) | alignment | ||
Range on Protein: 1445-1644
Range on HMM: 3-164/174.0
EYINASYIDGYSSSNKFIATQGPMVntladFWRLIWQERPMHIVMLTDPKEcIKNKWCEQYWPRalmeeekfgpfivtltnvanhpsftirslnviipDG
|||||..|.. ....||.|||. ||....... ..|||...|| .. .| .|||. .
dyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleeke.lglykcinywpe..................................lr
SNDSHTLTQYHLTSWPDHGVPKPLLsLHK---QVMATWS-PSEGPILVHCSAGVGRTGTFIAIDIALEQADrEGVVDIAGIVNRLRQQRMKMVQTLDQYV
. ... ||. . ||||||| |.. .| | ...||.|||||||||||||..|... | . |..||. .| .||.||..|||| .||
edlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyr
FLHD
||..
flyy
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 1445-1646 | 3.1e-39 | 129.9 | In-house | 13-169 (176) | alignment | ||
Range on Protein: 1445-1646
Range on HMM: 13-169/176.0
EYINASYIDGYsssnKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRalmeEEKFGPfivtltnvanhpsftirslnviipdg
||||..|.|. ..||||||...|||||........ ..|.||...| . | | .|||. .||.|
dyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlk.cpnywpe....leklgi..........................
sndshtltQYHLTSWPDHGVPKPlLS--LHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEqadrEGVVDIAGIVNRLRQQRM-KMVQTLDQYVF
||. . ||||||| . . .. . ||.|||||||.|||||..|... | ... .. ..|.||. ..||| .|| |
........qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaayllel....ekglsveealalvreqRplgavqtpeQyrf
LHDAV
|....
lyefe
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 1445-1645 | 1.2e-33 | 111.2 | In-house | 4-148 (151) | alignment | ||
Range on Protein: 1445-1645
Range on HMM: 4-148/151.0
EYINASYIDGYsssnkFIATQGPmvntLADFWRLIWQERPMHIVMLTDPKECIknkWCEQYWPRALmeeekfgpfivtltnvanhpsftirslnviipdg
|||.||..|. .....|| ||||..|.... .||.|....| .| .|.|..
dyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg...ycpeylpelg..................................
sndsHTLTQYHLTSWPDHGVPKPLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQadregvVDIAGIVNRLRQQRMKMVQTLDQYVFLHD
..........|||.|.| . .. . . . ....||.|||||||.|||||..|... |.. |... ... .|..|. .||. .|..|..
....ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
A
|
a
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 1451-1644 | 1.7e-39 | 130.3 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 1451-1644
Range on HMM: 1-144/152.0
YIDGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKEcIKNKWCEQYWpralmeeekfgpfivtltnvanhpsftirslnviipdgsndsht
.|||| ...|||||||. ||||||||.... .|||||.. | .. .||||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltelle.lgklkceqyi............................................
ltQYHLTSWPDHGVPKPLLSLHKQVMAT---WSPSEGPILVHCSAGVGRTGTFIAIDIALeqadreGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHD
||. . |||||||. | . . . ..||.|||||||||||||..|... | |.. .|...|..|...|.. .|. ||..
..qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1453-1642 | 7.8e-19 | 62.2 | In-house | 84-280 (302) | alignment | ||
Range on Protein: 1453-1642
Range on HMM: 84-280/302.0
DGYSSSNKFIA-TQGPMVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVAN-HPSFT------IRSLNVIIPDG
|| .| | .|| .| || | . .| |.. .| ..| | .|. . .| ||| . |. .| . || . ....
dGtekkekvskkpivpkkstlekhwalieqynvaivvqlcsfvedeekk.caeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekk
-SNDSHTLTQYHLTSWPDHGVPKPLLSLHkQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFL
.. .|. . ..||||| || . ... .|||||||||||||..|| .. .. | |.. || .|| | ||. .| ..|
kkkvkktvdilafsawpdhGapkeaytal.dilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyl
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1453-1538 | 1.4e-11 | 38.4 | In-house | 230-310 (440) | alignment | ||
Range on Protein: 1453-1538
Range on HMM: 230-310/440.0
DGYSSSNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDpkecIKNKWCEQYWPRALmEEEKFGPFIVTLTNVANHPSFTIRSLN
.||| | ||||| |. |. |||||. . | |.|| . ...| | ||| |||| | | .|.|.
egyskknafiatqmpldstvldfwrlvhdyristiimlnq....lndktcsiywpvnt.rsvtfgpftvghkgsenmnrvkvrtle
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1458-1643 | 7.1e-28 | 92.1 | In-house | 4-197 (199) | alignment | ||
Range on Protein: 1458-1643
Range on HMM: 4-197/199.0
SNKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECiKNKWCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSND-SHTLTQYHL
..|||| |. .|.||||...|. ||||. | . |. ||| . |.| . || .. .| .|| .| . . . ...| .
qrryiatqhplretmadfwqmvwetgsghivmvnddqkn.keadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
TSWPDHGVPKPLLSLH-----KQVMATWS-PSEGPILVHCSAGVGRTGTFIAIDIALEQA--DREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLH
||| .. |. | . ..| . . |..|||| | | || |.|.|| . . |||. . .|||| | .. .|..| |..
tswkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1459-1643 | 8.3e-28 | 91.9 | In-house | 4-196 (198) | alignment | ||
Range on Protein: 1459-1643
Range on HMM: 4-196/198.0
NKFIATQGPMVNTLADFWRLIWQERPMHIVMLTDPKECiKNKWCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDGSND-SHTLTQYHLT
..|||| |. .||||||...|. ||||. | . |. ||| . |.| . || .. .| .|| .| . . . ...| .|
rryiatqhplretladfwqmvwetgsghivmvnddqkn.keadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
SWPDHGVPKPLLSLH-----KQVMATWS-PSEGPILVHCSAGVGRTGTFIAIDIALEQA--DREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLH
|| .. |. | . ..| . . |..|||| | | || |.|.|| . . |||. . .|||| | .. .|..| |..
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 1468-1635 | 4.7e-15 | 50.2 | In-house | 43-212 (263) | alignment | ||
Range on Protein: 1468-1635
Range on HMM: 43-212/263.0
MVNTLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDgSNDSHTLTQYHLTSWPDHGVPKP
.|.|.. |.. | | .. .|||.| .| ..| |..|.| . | |. |. |.| . . . | .. . ||...| . |... |.
lvqtidkfyqtivqtktevvvmLcDfneegvek.cssyfPlekdekqklanvnvcttkvqsdvllktlellstlge.KkkthtvkhysykgWiekndpel
LLSLHKqVMATWSPSeGPILVHCSAGVGRTGTFIAIDIALE------QADREGVVDIAGIVNRLRQQRMKMVQT
. . .. | .. ||||.|.||. | .... . . .| ... ||..| . ..|
areiln.ilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraiht
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1471-1636 | 3.5e-17 | 57.3 | In-house | 40-207 (255) | alignment | ||
Range on Protein: 1471-1636
Range on HMM: 40-207/255.0
TLADFWRLIWQERPMHIVMLTDPKECIKNKwCEQYWPRALMEEEKFGPFIVTLTNVANHPSFTIRSLNVIIPDgSNDSHTLTQYHLTSWPDHGVPKPLLS
|.. |.. | | .. .|||.| .| ..| |..|.| . | |. || |. .... . . . . . ||.. |. . |... |.
tvdkfyqtivqtktevvvmlcdfaeegvek.cssyfplekdeklkladvnvtttkssadvvlrtleitstlge.kkkthtvkhysykGWieknaPelare
LhKQVMATWSPSeGPILVHCSAGVGRTGTFIAIDIALE------QADREGVVDIAGIVNRLRQQRMKMVQTL
. .... | ...||||.|.||. .|. .... . . .| ... ||..| . ..|
i.lnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtP
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 1504-1645 | 2.6e-26 | 87.4 | In-house | 1-138 (145) | alignment | ||
Range on Protein: 1504-1645
Range on HMM: 1-138/145.0
QYWPRALMEEEKFGPFIvTLTNVANHPSFTIRSLNVIIPDGSNDSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMaTWSPSEGPILVHCSAGVGRTGTF
.||| . .|.. | .... .. |. . . .. .. ... .||. ..||||||| ||.. ... .. ...||.|||||||||||||.
pywpseilpglylgslp.taldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefie.ealkeggpvlVHCsaGvgRtgtl
IAIDIALEqadrEGvVDIAGIVNRLRQQRMKMVQTLDQYVFLHDA
.|... |. .| |.. .....|.||...|.. .|. ||...
vaaylmll....lg.vsleealelvrsqrpgavpnpgqlrflyef
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 1522-1644 | 3.9e-24 | 80.4 | In-house | 18-139 (144) | alignment | ||
Range on Protein: 1522-1644
Range on HMM: 18-139/144.0
TLTNVANHPSFTIRSLNVIIPDGSNDSHTLT--QYHLTSWPDHGVPKP---LLSLHKQVmATWSPSEGPILVHCSAGVGRTGTFIAIDIALeqadREGvV
|. .... .. |. . .... ... . . ||. ..||||||| ||.. . . .. ...||.|||||||||||||..|... . ..| .
taldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefi.eealeeggpvlVHCsaGvgRtgtlvaaylmk....klg.l
DIAGIVNRLRQQRMKMVQTLDQYVFLHD
.. .....|..|. .|.. .|. ||..
sleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1547-1690 | 1.8e-27 | 90.8 | In-house | 87-233 (440) | alignment | ||
Range on Protein: 1547-1690
Range on HMM: 87-233/440.0
DSHTLTQYHLTSWPDHGVPK---PLLSLHKQVMATW-SPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFL
.|.|| ||| .|||.|||| |.| . ..| . ..||.|||||||.|||| ||.| | .| | .|| ..| .|..| .|||| .||.|.
esrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafv
HDAVFsETIIGGETEIPADKFATKLQELKEIDSSTGCSGLQSQFELLS
|.||. | .. |.| | | . ...... . | | || .|| |
heavl.egllcgdtliledditerveqiqwpnphtdksplqqefegys
|
|||||||||
| PTEN_1 | 1548-1602 | 6.7e-09 | 30.8 | In-house | 91-149 (196) | alignment | |||
Range on Protein: 1548-1602
Range on HMM: 91-149/196.0
SHTLTQYHLTSWPDHGVPKPLLSLH--KQVMATWS--PSEGPILVHCSAGVGRTGTFIA
. .|. ...|||.| .. |... .. |... .|||| ||.||.|| .|
fksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvva
|
|||||||||
| PTPc_DSPc_SM00012 | 1551-1647 | 2.2e-33 | 110.0 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 1551-1647
Range on HMM: 2-104/105.0
LTQYHLTSWPDHGVP---KPLLSLHKQVMATWSPSE--GPILVHCSAGVGRTGTFIAIDIALEQADRE-GVVDIAGIVNRLRQQRMKMVQTLDQYVFLHD
...|| |.||||||| ...|.| ..|. . || .|..|||||||||||||.|.||.|.| ..| . ||| ||..||.||..||||..||.||..
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AVF
|.
all
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 1553-1603 | 2e-07 | 26.3 | In-house | 81-135 (194) | alignment | ||
Range on Protein: 1553-1603
Range on HMM: 81-135/194.0
QYHLTSWPDHGVPKPLLSLHKQVMAT--W--SPSEGPILVHCSAGVGRTGTFIAI
.|. .||.|.. .| |.. . . . ..| ..||| ||.|||||..|
eylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa
|
|||||||||
| subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1554-1644 | 1.5e-08 | 29.3 | In-house | 85-170 (182) | alignment | ||
Range on Protein: 1554-1644
Range on HMM: 85-170/182.0
YHLTSWPDHGVPKPLLSLHKQVMATWSPSEGPILVHCSAGVGRTGTFIAIDIALEQAdregvVDIAGIVNRLRQQRMKMVQTLDQYVFLHD
.. .|.|.||. | ... . .|| . ||| || |||| || . . .. . .. .|..| | .|| .| ....
vynfgwkDygvasleriLdivkvvafalqegkvavhChaGlGrtGvliacylvyakr.....ltaekaiklvrskrpksiqtreqvelvke
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1580-1648 | 1.2e-16 | 55.5 | In-house | 225-293 (297) | alignment | ||
Range on Protein: 1580-1648
Range on HMM: 225-293/297.0
SPSEGPILVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVFS
| . ..||||||||||.| . |. |.. .. . |.| |.. ||.|| ..||||.|. .|.|||.
mprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1582-1645 | 1.2e-16 | 55.3 | In-house | 246-310 (319) | alignment | ||
Range on Protein: 1582-1645
Range on HMM: 246-310/319.0
SEGPILVHCSAGVGRTGTFIAIDIALEQADRE-GVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDA
| ||. |||| ||||||. || |||... . ||| .| .|..| . |.| .|| |..
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykv
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1584-1646 | 1.3e-16 | 55.3 | In-house | 263-340 (350) | alignment | ||
Range on Protein: 1584-1646
Range on HMM: 263-340/350.0
GPILVHCSAGVGRTGTFIAIDIALE-------------QADREG-VV-DIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
|||||||||||||||....| |. . |. . | |||.||.||..|||.|||..|...|.
spilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeal
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1584-1646 | 1.4e-11 | 38.3 | In-house | 266-340 (349) | alignment | ||
Range on Protein: 1584-1646
Range on HMM: 266-340/349.0
GPILVHCSAGVGRTGTFIAIDIALE---QADREGV--------V-DIAGIVNRLRQQRMKMVQTLDQYVFLHDAV
..||||||| ||||... .|. |. .| . | ||| ||.||. ||| | |......|.
stllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyeal
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1587-1647 | 2.7e-14 | 47.3 | In-house | 2-62 (69) | alignment | ||
Range on Protein: 1587-1647
Range on HMM: 2-62/69.0
LVHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
.||||.| ||||||||| . . . | .||| |. .|. | || .|.|.|||.
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalv
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1588-1647 | 3.8e-14 | 46.8 | In-house | 2-61 (69) | alignment | ||
Range on Protein: 1588-1647
Range on HMM: 2-61/69.0
VHCSAGVGRTGTFIAIDIALEQADREGVVDIAGIVNRLRQQRMKMVQTLDQYVFLHDAVF
||||.| ||||||||| . . . | .||| |. .|. | || ..|.|.|||.
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalv
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 1654-1909 | 6.3e-57 | 188.6 | In-house | 1-286 (288) | alignment | ||
Range on Protein: 1654-1909
Range on HMM: 1-286/288.0
GETEIPADKFATKLQELKeidsSTGCSGLQSQFELLSQVTPDlDDATEDNAGEDLAKNQ--------------------GSNSYTNPSFTAGYHDKKAFI
|.|||...... ...|. .| .||. .|| | ...|| . . . | | ||. ....| | |. ||. |..||
gdteisveellklvlkll....angltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfI
IAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYW--TGLSTHDDFVVEIANEIKSNGYIERMLNVE----------SRNVLQLQVTDWPQD
..| |..|| |||.|. ...|. ||||..... |..|| | |..|..|.. .| . ..|. | | |. ||.| ....|.|| .
atqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdh
GVVREPRTVLQVIDDVIHRQQkIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYL
|| |. .|. . .|.. .. ||||||||||. |.|.|... . . ||| ..||.|||... | .|. .||.|.|.||| .|... .||
gvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 1662-1911 | 1.1e-57 | 191.0 | In-house | 24-301 (308) | alignment | ||
Range on Protein: 1662-1911
Range on HMM: 24-301/308.0
KFATKLQELKEIDSSTGCSGLQSQFELLSQVTPdLDDATEDNAGEDLAKNQ---------------GSNSYTNPSFTAGY--HDKKAFIIAQSPMENTAR
. . |. || ... .. ..|. .|| | .|.| | . . . | ||. ....| | |. || . ...||..|.|..||
lklsvldllkllekaldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkldegsdYInAsyvdgyssklprkfIatqgPlpntve
DFWKMIVDYKVSAIVMLCGEEDC----CYPYW-----TGLSTHDDFVVEIANEIKSNGYIERMLNVES------RNVLQLQVTDWPQDGVVREPRTVLQV
|||.|. ...|. ||||. ... |..|| | ....|.|.. .| . ..|. | | .. | | ... |.|| .|| .|. .|.
dFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldf
IDDVIHRQqkiGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQM
.. | ... .|||.|||||. |.|.|... . . ||| ..|| ||||.. | .|. .||.|.|.||| .|... .||.
lelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 1665-1912 | 2.1e-53 | 177.1 | In-house | 17-292 (297) | alignment | ||
Range on Protein: 1665-1912
Range on HMM: 17-292/297.0
TKLQELKEIDSSTGCSGLQSQFELLSQVTPDlddATEDNAGEDLAKNQGS---------------------NSYTNPSFTAGYHD-KKAFIIAQSPMENT
. | |. .. .....|. .|| | ...|| .. . | ||. . ..| | |. ||. ...||..| |...|
svldlllllekansktllllefeellslkpd...ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpet
ARDFWKMIVDYKVSAIVMLCGEEDC---CYPYW-T--GlsTHDDFVVEIANEIKSNGYIERMLNV----ESRNVLQLQVTDWPQDGVVREPRTVLQVIDD
|||.|. ...|..||||. .... |..|| . | |..||.|. .... .||. | |.| ||| | ..|.|.|| .|| ....|....
vedFwrmvweqgvtvivmLtklvelgrkcaqywpeegg..tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflel
VIHRQQKI-GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQMN
| ..... .||||.||||. |.|.|... . |||.. || |||... | .|. .||||.|..|| .||.. ..|. .
vrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 1665-1909 | 1.1e-52 | 175.0 | In-house | 12-304 (307) | alignment | ||
Range on Protein: 1665-1909
Range on HMM: 12-304/307.0
TKLQELKEIDSSTGCSGLQSQFELLSQVTPD-LDDATEDNAGEDLAKNQ---------------------GSNSYTNPSFT--------AGYHDKKAFII
.|| |. .. .. .||. .|| | .||.. |.. .. . | ||. ....| | |. ||. |..||.
lkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIa
AQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWT---GLSTHDDFVVEIANEIKSNGYIERMLNVE-------SRNVLQLQVTDWPQDGVV
.|.|...| |||.|. ...|..||||...... |..|| . |...|.|. .| . .||. | |.|. || | ... |.|| .||
tqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvp
REPRTVLQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGV---VDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYL
. ..|. |. | . ... .||||.||||. |.|.|... . |.| ..||. ||.... | .|. .||||...||| .|... ..|
psfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1666-1914 | 5.6e-105 | 345.3 | In-house | 20-298 (301) | alignment | ||
Range on Protein: 1666-1914
Range on HMM: 20-298/301.0
KLQEL---KEIDSSTGCSGLQSQFELLSQVTPDLDDATEDNAGEDLAKnqGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC
. .|| .. .. |.| ..... ..|. |. . ..| . ...|.| |. || .||.||.||.||..| .|||..|...|...|||..
qykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldl..cqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvt
GEEDC----CYPYWTGLSTHDDFVVE----IANEI-----------------KSNGYIERMLNVESR----NVLQLQVTDWPQDGVVREPRTVLQVIDDV
..... |. || ..... ... . || .||||||...|.|. .||||||||||||||||||||||||||||
nlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddv
IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQMNKA
||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||.|..
ihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnst
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1666-1913 | 4.4e-65 | 214.5 | In-house | 6-282 (287) | alignment | ||
Range on Protein: 1666-1913
Range on HMM: 6-282/287.0
KLQELKEIDSSTGCSGLQSQFELLSQVTPDLDDATEDNAGEDLAKNQG----------------SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKM
|. |. . . .| | . || .| ||| . |. | . | .. ||. . | | .| ||..|||||||.||| ||||.|||.
kfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllkgehpdyinavfidgykekkafiiaesPmfntarnfWkl
IVDYKVSAIVMLCG----EEDCCYPYWTGLS--THDDFVVEIANEIKSNGYIERMLNVESRN-------VLQLQVTDWPQDGVVREPRTVLQVIDDVIHR
| | .|.|||||| .|. || ||. . . .. .|. || ...||||| |.|. .| | | |.|.|.. | | ||.|.| ||.. ..
iddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemykt
QQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQMNK
|.| | ...|||||||| ||...|.. .....|| |||.||||| | | |||.| | |||. |.|.. .||. .
qrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfe
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 1670-1912 | 8.6e-55 | 181.5 | In-house | 3-280 (297) | alignment | ||
Range on Protein: 1670-1912
Range on HMM: 3-280/297.0
LKEIDSSTGCSGLQSQFELLSQVTPdLDDATEDNAGEDLAKNQGS----------------NSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDY
|| ...... ..|...|| | .. . | . . . | | ||. . ..| | |. ||. |..||..| |..|| |||.|. ..
lkllekllflalllkefeellplll.lgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweq
KVSAIVMLCGEEDC----CYPYW----TGLSTHDDFVVEIANEIK--SNGYIERMLNVES------RNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQ
.|. ||||. ... |..|| . |..||.|. .. . ...|. | | |. | | ....|.|| .|| |...|. |. | ...
nvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvl
QKI-GGGPVVVHCSDTVSRSGVYCSVSIGLEQCK---AEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQMN
... .||||.||||. |.|||... . . |.| . || ||.... | .|. .||||.||||| .|... ..|. .
kllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 1672-1909 | 2.2e-54 | 180.1 | In-house | 4-272 (273) | alignment | ||
Range on Protein: 1672-1909
Range on HMM: 4-272/273.0
EIDSSTGCSGLQSQFELLSQVTPdLDDATEDNAGEDLAKNQG----------------SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKV
.....| ..|. .|||| ...| | . . . | . ||. ...| | |. ||. |..||..| |..|| |||.|. ...|
llekllgltllleefelllslkp.lltysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnv
SAIVMLCGEEDC----CYPYWTGLS-----THDDFVVEIANEIKSNGYIERMLNVES------RNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKI
. ||||. ... |..|| |...| |.. .| . ..|. | | ... | | ....|.|| .|| . .|. |..| . ....
rviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkaleal
-GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYL
..||||||||. |.|.|... . . |.| ..|| |||... | .|. .||.|.|.||| .|... .||
psngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 1675-1909 | 1.3e-50 | 167.8 | In-house | 15-277 (278) | alignment | ||
Range on Protein: 1675-1909
Range on HMM: 15-277/278.0
SSTGCSGLQSQFELLSQVTPdlDDATEDNAGEDLAKNQGS--------------------NSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYK
.....|. .|| | .... |. . . | ||. . ..| | |. ||. ...||..| |...| |||.|. ...
llnlktllllefeellsfkl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelg
VSAIVMLCGEEDC----CYPYW-TGLSTHDDFVVEIANEIKSNGYIERMLNVES------RNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQkIGGG
|. ||||..... |..|| | |..||.|. .|.. ..|. | |.|. | |.... ..|| .|| . ..|. . .|..... .|
vttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsng
PVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYL
||.||||. |.|.|... . . ||| . || ||.... | .|. .||||.|..|| .|... .||
pvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 1680-1912 | 1.5e-53 | 177.5 | In-house | 18-279 (317) | alignment | ||
Range on Protein: 1680-1912
Range on HMM: 18-279/317.0
SGLQSQFELLSQVTPDldDATEDNAGEDLAKNQG--------------------SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIV
.|...|| | ....| . .. . | ||. ...| | |. |.. |..||..|.|..|| |||.|. ...|. ||
talleefedllslkld..tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtviv
MLCGEEDC----CYPYW--TGLSTHDDFVVEIANEIKSNGYIERMLNV------ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQkiG-GGPVV
||. .|.. |..|| . |..||.|.. .|.. .|.. | | | ||| | ... |.|| .|| |...|. .. | . .. . ||||.
mLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale..dpggpvl
VHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQMN
||||. |.|.|... . . |||.. || |||... | .|. .||||.|.||| .||.. .||. .
VHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 1681-1911 | 6.3e-55 | 181.9 | In-house | 1-276 (284) | alignment | ||
Range on Protein: 1681-1911
Range on HMM: 1-276/284.0
GLQSQFELLSQVTPDLD-DATEDNAGEDLAKNQ---------------------GSNSYTNPSFTAGY-----HDKKAFIIAQSPMENTARDFWKMIVDY
||. .|| | ..|..| . . .. | | ||. ....| | |. || . ||.||..| |..|| |||.|. ..
gleeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweq
KVSAIVMLCGEEDC----CYPYWTGL---STHDDFVVEIANEIKSNGYIERML-------NVESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQK
.|. ||||..... |..|| |..|| |.. .| . ..|. |.| . ||| | ....|.|| .|| .|. .|. ...| . ...
nvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellen
-IGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEG---VVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQM
||||.|||||. |.|.|... . . ||| ..|| .|||... | .|. .||.|.||||| .|... .||..
lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylkl
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1702-1773 | 1.1e-10 | 35.4 | In-house | 204-280 (440) | alignment | ||
Range on Protein: 1702-1773
Range on HMM: 204-280/440.0
DNAGEDLAKNQGSNSYTNPSF----TAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED-CCYPYWT
|. | . . | | .|. | || |.||| .| |.. | |||... ||..|.|.|| .| | ||
dditerveqiqwpnphtdksplqqefegyskknafiatqmpldstvldfwrlvhdyristiimlnqlndktcsiywp
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1704-1761 | 9.1e-07 | 22.6 | In-house | 49-107 (332) | alignment | ||
Range on Protein: 1704-1761
Range on HMM: 49-107/332.0
AGEDLAKNQGSNSYTNPSFTAGYHDKKAFIIAQSPMEN-TARDFWKMIVDYKVSAIVML
. .|| ..| . . | |. || | |.|.||.|... | ||.|. . | | |...
srvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvf
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1707-1820 | 5.2e-11 | 36.6 | In-house | 114-236 (244) | alignment | ||
Range on Protein: 1707-1820
Range on HMM: 114-236/244.0
DLAKNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC--GEEDCCYPYWTGLSTH-DDFVVEIA------NEIKSNGYIER
|.| .|.| | || .|..| |. .|. |||||... .| .|.| ||| .| | . .| | .. | || ||
plskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveeedeywpdseplewyeeditvtltdrdefknikasnleies
MLNVESRNVLQLQVTDWPQDGVV
.| . . .|...|| ||
dmneshqaltmfqisnwpsdgtt
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 1708-1909 | 3.8e-37 | 122.7 | In-house | 69-287 (563) | alignment | ||
Range on Protein: 1708-1909
Range on HMM: 69-287/563.0
LAKNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYW--TGLSTHDDFVVEIANEIKSNGYIERMLNV
|. .... | | .. ||. .||||..| |...|. |||.|| . .|. |||. . | || . | . . | . .| . | .| | .
lpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlvi
ES------------RNVLQLQVTDWPQDGVVREPRTVLQVIDDViHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKP
. ..| | . |.||. || . ||. . . .| ||.||||| |.|.|.|. .. |.| ..| .|.||.. | .| ..
knlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkks.saankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRn
GAVTTLEQYTSIYDVIDMYL
|.| |||. ..|.. .
flvqteEqYiflhdalleai
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 1709-1905 | 2.1e-50 | 166.7 | Pfam-A | 21-233 (235) | alignment | ||
Range on Protein: 1709-1905
Range on HMM: 21-233/235.0
AKNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWT----GLSTHDDFVVEIA-NEI-KSNGYIERM
...|.. | | .. ||..||.||..| |...| |||.|....||..||||. .|. | .|| . |..|. ||. .| ....|. |
kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrk
LNVE-------SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGA
|... .| | ||..|.||. || ..|. .|..|..| ... . ||||||||. |.|.|......| |||..||. |||.|. | .||..||.
lelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgm
VTTLEQYTSIYDVI
|..|||| .|..|
vqsleqYiflykai
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 1709-1905 | 2.1e-50 | 166.7 | In-house | 21-233 (235) | alignment | ||
Range on Protein: 1709-1905
Range on HMM: 21-233/235.0
AKNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWT----GLSTHDDFVVEIA-NEI-KSNGYIERM
...|.. | | .. ||..||.||..| |...| |||.|....||..||||. .|. | .|| . |..|. ||. .| ....|. |
kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrk
LNVE-------SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGA
|... .| | ||..|.||. || ..|. .|..|..| ... . ||||||||. |.|.|......| |||..||. |||.|. | .||..||.
lelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgm
VTTLEQYTSIYDVI
|..|||| .|..|
vqsleqYiflykai
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1709-1906 | 9.7e-39 | 128.1 | In-house | 71-276 (315) | alignment | ||
Range on Protein: 1709-1906
Range on HMM: 71-276/315.0
AKNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC----GEEDCCYPYWTGL-STHDDFVVEIANEIKSNGYIERMLNVES
.|. | | .| || |. .| ||.| .. .|||... ..... |||| ||. . || .. . | .| . . | | | | .
lendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdkkviyGkitvtrkseevnteytvrtlsvvf
----RNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGgGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYT
|.|.||..| ||. || . .....| | ... |..|||||. | |.| ..... |.| .|| ..||... . ||. . ..| ..|||
gdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsv.gaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyq
SIYDVID
|||..
fiydall
|
|||||||||
| DSPc_SM00195 | 1710-1909 | 4.3e-50 | 165.9 | In-house | 47-262 (263) | alignment | |||
Range on Protein: 1710-1909
Range on HMM: 47-262/263.0
KNQ--GSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWTGL----STHDDFVVEIANEIKSN-GYIERM
|.. ...| | .. |.. ||..|..| |...| .|||.|... ||. ||||. ||.. |. || .|.... |.. ...| . .| |
keekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrt
LNVESRN------VLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAV
|... . | |.|...||. || ... ||... | ...... ||.|||||. |.|.|......| |.....| ||.|.. |..||..||.|
leltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmv
TTLEQYTSIYDVIDMYL
.|||||. ||..| |.
qtleqYlfiyeaileyi
|
|||||||||
| PTPc_SM00194 | 1710-1909 | 4.3e-50 | 165.9 | In-house | 47-262 (263) | alignment | |||
Range on Protein: 1710-1909
Range on HMM: 47-262/263.0
KNQ--GSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWTGL----STHDDFVVEIANEIKSN-GYIERM
|.. ...| | .. |.. ||..|..| |...| .|||.|... ||. ||||. ||.. |. || .|.... |.. ...| . .| |
keekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrt
LNVESRN------VLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAV
|... . | |.|...||. || ... ||... | ...... ||.|||||. |.|.|......| |.....| ||.|.. |..||..||.|
leltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmv
TTLEQYTSIYDVIDMYL
.|||||. ||..| |.
qtleqYlfiyeaileyi
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 1710-1910 | 1.1e-37 | 124.6 | In-house | 63-278 (290) | alignment | ||
Range on Protein: 1710-1910
Range on HMM: 63-278/290.0
KNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE----DCCYPYWTGLS----THDDFVVEIANE-IKSNGYIERMLN
... ..| | .| | ..|...| ||.|. .| |||.|| ...|. .||.| | | ||. ....| |. .| ..... |.|.
eeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLk
V----ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQkIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGV---VDVFQVTKAVRKSKPGAVT
| |||.| |.. |.|| || . . ..|..|..| ..|. |.||||| | | |. ... . |. ||| . .|||.. .|| .. .|
veaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvq
TLEQYTSIYDVIDMYLQ
| |||. .| . ..|
tkeqyelvykavaelvq
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 1710-1913 | 1.6e-35 | 117.6 | In-house | 74-289 (293) | alignment | ||
Range on Protein: 1710-1913
Range on HMM: 74-289/293.0
KNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC--GE--EDCCYPYWTGL---STHDDFVVEIANEIKSNGYIERMLNVE
|.. .. | | .. ||. .. || .| |. .| |||.|. . |.|.|||| | | || .. | |.. .| . . .. | |..|
kdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkie
----SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQ-QKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQ
.|.| |.. | ||. || ...|.|. . | ... .. .|.||||| | |.|.. .. |.. . | .||.| . ..|... | | .|
kekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekq
YTSIYDVIDMYLQMNK
| |.... .|. ..
Yifihqcvldllrkke
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1710-1909 | 5e-34 | 112.9 | In-house | 71-288 (325) | alignment | ||
Range on Protein: 1710-1909
Range on HMM: 71-288/325.0
KNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVML---CGEEDCCYPYWTGL----STHDDFVVEIANEIKSNGYIERMLNV-
|...| | | |. . .|. |. ||.|. .| |.|....|.. | .|.| ...| | || | . |.. . |. |.|.|
kddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvk
-----ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKI-----GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGA
|.| | |.|. |.. || . | |.. ... | . .... . .|..||||. | |.||. |. |.. | ||.|.. | .|| .|
qvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsm
VTTLEQYTSIYDVIDMYL
| | .||. ||. . ..
vetvdqyiliyealveay
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1710-1905 | 2e-26 | 87.7 | In-house | 23-235 (237) | alignment | ||
Range on Protein: 1710-1905
Range on HMM: 23-235/237.0
KNQGSN-SYTNPSFTAGYHD-KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYWTGLS---THDDFVVEIANEIKSNGYIERMLN
| ||. | | .. |. | .| || |.|.. |||.|. . | | |||| | .| |. || .. . | . . . | | |
kgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaaygvltvslkkkeefsdytvrsll
VE-------SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAV
. | . | | | ||. || .. ..|. ..|.| ... || ..||| | |.|.. . | |.| . |||... ... . .| .
lskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyii
TTLEQYTSIYDVI
| .|| |...|
qtkdqyvfihqti
|
|||||||||
| subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1710-1761 | 2.4e-06 | 21.3 | In-house | 65-116 (347) | alignment | ||
Range on Protein: 1710-1761
Range on HMM: 65-116/347.0
KNQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVML
. . ...| | | .| .|..| |. .| ||||||. ||. .| .
raddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1711-1913 | 1.1e-81 | 269.3 | In-house | 70-287 (305) | alignment | ||
Range on Protein: 1711-1913
Range on HMM: 70-287/305.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC----GEEDCCYPYWTGLSTH----DDFVVEIANEIKSNGYIERMLNV-
... . | | |. ||. ||..|.||.|..|| .|||..||..||| ||||. |..|.|. ||.. |. ..|.||. .| . ..|||| |..
slddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkis
------ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTL
|||.|||.|.||||..||.... ..|..|..| ..|.| | |..||||..|.|.||...|.| ||..|.|.|||||.|.|..|......|.||
iededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtl
EQYTSIYDVIDMYLQMNK
.||....|..| ... .
dqYvflhdaldelitcgd
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 1711-1914 | 5.9e-52 | 172.1 | In-house | 72-286 (564) | alignment | ||
Range on Protein: 1711-1914
Range on HMM: 72-286/564.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE----DCCYPYWTGL--STHDDFVVEIANEIKSNGYIERMLNV---
.. . | | || ||. .||.| .| |...| .|||.|. ....| |||| | . | || |.....|.. .| . . |. | ...
gdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkk
---ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQqKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
|||.| | . |.||. || .....|..|..| . . . . ||.||||| | |.|... ... ||. |.|..||..|. ||.|| .. | | |||
kssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQY
TSIYDVIDMYLQMNKA
|...| .|.. .
iFiheailealacgnt
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1711-1914 | 4.9e-49 | 162.1 | In-house | 71-285 (318) | alignment | ||
Range on Protein: 1711-1914
Range on HMM: 71-285/318.0
NQGSnSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWTG--LSTHDDFVVEIANEIKSNGYIERMLNV---
..|| | | .. ||. |||.| ||.|. .| .|||.|. . . . |||| ||. . || . .... |||. .|.... |. | ..|
eegs.DyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrt
---ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
|||.| | ..|.||. || .. ..|... .| . ||| | ||.||||| | | ||.. |.| ||. |||..|||||. | .|. .. | | .||
eeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqy
TSIYDVIDMYLQMNKA
. ||||. .|. ..
efiydvllealasgdt
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 1711-1909 | 4.3e-48 | 159.5 | In-house | 35-246 (249) | alignment | ||
Range on Protein: 1711-1909
Range on HMM: 35-246/249.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYW--TGLSTHDDFVVEIANEIKSNGYIERMLNVE--
. ..| | |. ||. |..||..| |...| |||.|. ......||||. .. . |..|| | ...||.|. .......|. |.| ..
glflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnl
----SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKI-GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQ
|| ||..|.|||| .|| . ..|. |. | . .... ||||.||||. |.|.|... . ||| . |. ||.... | .|. .||||...||
ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeq
YTSIYDVIDMYL
| .|... ..|
yrflyeallell
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1711-1913 | 2.3e-39 | 130.3 | In-house | 75-288 (297) | alignment | ||
Range on Protein: 1711-1913
Range on HMM: 75-288/297.0
NQGSNSYTNPSFTAGYHDkkAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE---DCCYPYWT--GLSTHDDFVVEIANEIKSNGYIERMLNVESRN
.. . | | || |.. .| | ||..| |||.|..|..||.|||| .. . | ||. | .| | .|.. . .|.|.| |.|. .
ddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerdkkcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgk
------VLQLQVTDWPQDGVVR--EPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQ
| | | ..||.. | | . ...|..|..| . .. ||..|||. | | ||.... . . | | ||.|.. | .|...| | | ||
akarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeq
YTSIYDVIDMYLQMNK
|. .| .. .| ..
ykfvyvavleallsed
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1711-1911 | 1.8e-36 | 120.6 | In-house | 68-279 (315) | alignment | ||
Range on Protein: 1711-1911
Range on HMM: 68-279/315.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG--EEDC--CYPYWTG----LSTHDDFVVEIANEIKSNGYIERMLN--
.. . | | |. ...| ||.| .| | . . |||.|....||..|||. |.| | || . . ||. . . . | |
dsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtr
--VESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRqQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
|||.| | | |.||. || .. ..|..| .| .. ...|||| | |.|| .|. ..| | . .||||.. | .|. .| | | |.|
kseesrtvtqfqftewPdkGvdkqtssllklikevkad.ngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeey
TSIYDVIDMYLQM
. |||.. .|.
afiydavledllw
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1711-1906 | 4.9e-36 | 119.3 | In-house | 71-276 (288) | alignment | ||
Range on Protein: 1711-1906
Range on HMM: 71-276/288.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYWTGLST---HDDFVVEIANEIKSNGYIERMLNVE-
.. .. | | |. .|.. ||..| .|.|. .| |||... ..|.| |||| . .. | || . . .. |.. .. . . ...| | .|
eeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllek
---SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYT
... |.| . ||..|| . . .|.... | .|. ||..||||. | |.|.. .. ... ..| ..||. . . .||... | ||.||
kkteleitqyqylaWpdhgvPeskapllellrqvkvanqad.tgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYe
SIYDVID
||.|.
fiyevll
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1711-1910 | 4.6e-35 | 115.7 | In-house | 67-277 (515) | alignment | ||
Range on Protein: 1711-1910
Range on HMM: 67-277/515.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE----DCCYPYWTGLS----THDDFVVEIANEIKSNGYIERMLNV-
.. . | | |. ... ||.| .| | . . |||.......|..|.|. . | || . ||. | | | |.|
dnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvl
---ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGgGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
.|| | | . |.||. || .. ...|..| .| .... |...||| | | ||..|. . . | .||||.. . .|. .| | | |||
kgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqy
TSIYDVIDMYLQ
. ||... .|
afiygavledll
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1711-1911 | 5.9e-35 | 115.7 | In-house | 65-278 (281) | alignment | ||
Range on Protein: 1711-1911
Range on HMM: 65-278/281.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED----CCYPYWTGLS---THDDFVVEIANEIKSNGYIERMLNV--
.. .. | | .| .||...|..|..|.|. .. .||.|....|||||||. | . |. || . . |..|. .| ... |||| ...
enkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkler
---ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAE-GVVDVFQVTKAVRKSKPGAVTTLEQ
|.|.| ||. | ||. || ... .|. ..| . ..| |.|.||| | |.|.| .. .....|| .|| .| . .||.. | |. |
esgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvq
YTSIYDVIDMYLQM
|. .| .. .|.
yefvykavldaldk
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1711-1902 | 1.6e-23 | 78.1 | In-house | 32-234 (239) | alignment | ||
Range on Protein: 1711-1902
Range on HMM: 32-234/239.0
NQGSNSYTNPSFTAGYHD-KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYWTG-LSTHDDFVVEIANEIKSNGYIERML-----
|. . | | |. | ||.| .| .| .. |||.|. . . |||| | . |. || | . .. | . . || | .
ndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycnlrvtlrktevfadyiirtfvmsqv
-NVESRNVLQLQVTDWPQDGVVREPRTVLQVIdDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
. | | | | ..| ||. || . .|| . | .. | | |.||| | |.| . . | |.| . ||.|. ||.|. .| | | |||
gqteeryvyqyhftvwpdkgvpqyatavlglr.rkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqy
TSIY
|.
vfih
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1711-1902 | 1.6e-23 | 78.1 | In-house | 31-233 (239) | alignment | ||
Range on Protein: 1711-1902
Range on HMM: 31-233/239.0
NQGSNSYTNPSFTAGYHD-KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYWTG-LSTHDDFVVEIANEIKSNGYIERML-----
|. . | | |. | ||.| .| .| .. |||.|. . . |||| | . |. || | . .. | . . || | .
ndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskycnlrvtlrktevfadyiirtfvmsqv
-NVESRNVLQLQVTDWPQDGVVREPRTVLQVIdDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
. | | | | ..| ||. || . .|| . | .. | | |.||| | |.| . . | |.| . ||.|. ||.|. .| | | |||
gqteeryvyqyhftvwpdkgvpqyatavlglr.rkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqy
TSIY
|.
vfih
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 1711-1902 | 5.2e-23 | 76.2 | In-house | 52-264 (290) | alignment | ||
Range on Protein: 1711-1902
Range on HMM: 52-264/290.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC----GEEDCCYPYWTGLST-------HDDFVVEIANEIKSNGYIERML
....| | | |. . |. .|..| |. ||. ||.|. . | |.||| |. |. || . . |.. .| ... |. |.|
eradndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrll
NVES------RNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQ-KIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEG---VVDVFQVTKAVRKSKP
..| |..|. | || || . | . |. . .| . . ||.|.||| . ||| .| | | . .... ||. .| ..|| .
elenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrl
GAVTTLEQYTSIY
| . | .| |
Gliqtadqlrfsy
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 1711-1903 | 3.5e-21 | 70.2 | In-house | 80-286 (297) | alignment | ||
Range on Protein: 1711-1903
Range on HMM: 80-286/297.0
NQGSNSYTNPSFTAGYHDK-KAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED----CCYPYW--TGLSTHDDFVVEIAN-EIKSNGYIERM----
.. .. | | |. . |.| .|.|. .| |||.|. . | ||.|. |. |. || .| .... . |.. | .. |. |
saeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylk
--LNVESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIhRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQC-KAEGVVDVFQVTKAVRKSKPGAVTTL
. |.| | |. ||. || .....|. | . . |.|||||| . |.|||. . . |.. | .|. . .| .|| | |
nlqtsetrtvtqfhflswpeegvPasaksllefrrkvn.ksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktk
EQYTSIYD
.|. ..
dqfefalt
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1711-1905 | 1.6e-15 | 51.6 | In-house | 62-265 (281) | alignment | ||
Range on Protein: 1711-1905
Range on HMM: 62-265/281.0
NQGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYWTG----LSTHDDFVVEIANEIKSNGYIERMLNV-
|. | | . |. .|..| | ..| |||.|| . . .|||||| . . | |. | . |. . . . ||.
nknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnls
---ESRNVLQLQVTDWPQDGVVREPRTVLQVIddvihRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAE-GVVDVFQVTKAVRKS-KPGAVTTLE
|.| . . .||. | .|... |. . | |.||| | ||| .| | |. .. . |. |. .| . . .| ||.
yegetrlithwlwkewpdwqvpessevmlkil.....rkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlq
QYTSIYDVI
|| |. |.
qymliwkvl
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1711-1912 | 1.4e-12 | 41.6 | In-house | 70-288 (302) | alignment | ||
Range on Protein: 1711-1912
Range on HMM: 70-288/302.0
NQ-GSNSYTNPSFTAGYHDKKAFIIAQSPMENTA---RDFWKMIVDYKVSAIVMLCGEEDC------CYPYWTG-LSTHDDFV-----VEIANEIKSNGY
.. .|| | | . . .. |.|| | ... .||.|. . |. .|.| |||.. .| .| ...... || |.| |.. .
leaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkktlselfpkksgdykeygkmfvNnrkVekaeeektryv
IERMLNVESRNVLQL--QVTDWPQDGVVREPRTVLQVIDDViHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAV
|| . . | || .| |.|. | . .. . . .| . .. . ..|. . | |. .. . .|. ... . . .. |..|. .| ||
iEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakv.fakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRprav
TTLEQYTSIYDVIDMYLQMN
.|.||.|.| .. .|.. .
dslkQyvslyialllyikkk
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1712-1911 | 2.9e-64 | 211.7 | In-house | 73-285 (290) | alignment | ||
Range on Protein: 1712-1911
Range on HMM: 73-285/290.0
QGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYWTGLST--HDDFVVEIANEIKSNGYIERMLNVESRN
.|.| | .. ||..||..|..|.|..||..||||.|.. ||..||||. ... |. ||. .| . | ... || . |.|||| |.|...|
DCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknkn
-------VLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
| |.|.| |...| | .| |.|.|| ... | | | ...||||||||.||.|.|.. .....|| |||.||||| | | ||| |.| .||
sagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqy
TSIYDVIDMYLQM
|.... ||.
qgifqivltylds
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 1712-1905 | 4.7e-42 | 138.9 | In-house | 68-273 (314) | alignment | ||
Range on Protein: 1712-1905
Range on HMM: 68-273/314.0
QGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG-EED---CCYPYWTGL-STHDDFVVEIANEIKSNGYIERMLNVES---
. |. | | ... .|. .|||..| |...| .|||... |.. ..|||| | |. || ....|. ||. . . .. |...||
dpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedtevygdikvelvetellaelvvrifrveklar
-----RNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKiGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
| | |.| . ||. .| . ...|... | . |.. . |..||||| |.|... ..| |. . |||||||.. |..|..|. | | |||
gqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqy
TSIYDVI
. |||||
kfiydvi
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 1712-1908 | 3.6e-40 | 133.4 | In-house | 30-241 (243) | alignment | ||
Range on Protein: 1712-1908
Range on HMM: 30-241/243.0
QGsNSYTNPSFTAGYhDKkaFIIAQSPMENTARD----FWKMIVDYKVSAIVMLCGEE----DCCYPYWTGLSTHDDFVVEIANEIKSNGYIERMLNVES
.| ..| | ... .. .. .|. | |...| | ||.|. ......||||. .. |..|| | |..||.|.. .| ..|. |.| .|
eg.sdyinanliyvt.pr..liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllen
-------RNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQK-------IGGGPVVVHCSDTVSRSGVYCSVSIGLEQCkaeGvVDVFQVTKAVRKSKP
|.| ... . || || .| .|. .|.|. ... .||||.|||| |.|.|... . |... | ||.... | .|. .|
ldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRp
G-AVTTLEQYTSIYDVIDMY
| ||.|..|| .|... ..
gkavqtpsqyrflyeallel
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 1712-1912 | 1.9e-36 | 120.2 | In-house | 68-293 (296) | alignment | ||
Range on Protein: 1712-1912
Range on HMM: 68-293/296.0
QGSNsYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC---CYPYWTGL--STHDDFVVEIANEIKSNGY------IERM--
. |. | | .. .. ||..|. . |...| .||... | ..||.|.|. . | . || . ...||| .| . . ..
eksd.YinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfakmypsywpnkskeqygeifveiveekqyanlkirtfkltkkiv
--------LNVESRNVLQLQVTDWPQ-DGVVREPRTVLQVIDDVIHRQQKI----GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVR
..| | |...|.| |. | | ...... | ..|. |||||..|| .||||||... . ||. . |. ||||. | .|
alteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlr
KSKPGAVTTLEQYTSIYDVIDMYLQMN
.|.|. | . |.| ||||. .. .|
rsRpqLvenveeYkyiYdvlleavlcn
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 1712-1908 | 2.2e-31 | 104.0 | In-house | 67-289 (297) | alignment | ||
Range on Protein: 1712-1908
Range on HMM: 67-289/297.0
QGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG--E--EDCCYPYWT-GLST---HDDFVVEIANEIKSNGYIERMLNVE-
. | | .|. ||. ||||| .| |...| .|||.|. . .| ||| | | || . . . |. |. . ... | .|.|...
deasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleikn
-----SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQ------------KIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVR
||.| |.. || || .. ..|.|.. | ..| .. | |.||||| . |.| .... | |.. . .|.|||... | .|
vkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllr
KSKPGAVTTLEQYTSIYDVIDMY
. . .. | |||. | . |
tqrafsiqtpeqyefcylavley
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1712-1912 | 4.9e-26 | 86.2 | In-house | 62-280 (287) | alignment | ||
Range on Protein: 1712-1912
Range on HMM: 62-280/287.0
QGSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGE-ED---CCYPYWTGL----STHDDFVVEIANEIKSNGYIERML---N
. .| | . |.|.|..||| ||.|. | ||||..... ........ | |. || || || . .||. | | | .
elGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlid
VESRN---VLQLQVTDWPQDGVVRE----PRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVT
.|.|. | ||.. .||.... | ||.| . . ... . ||.|||.. . |||.. .. . ... . | ||| .| .|. . . |
letrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvq
TLEQYTSIYDVIDMYLQMN
. |. .|. . | . |
avvqlrllyealvtyyktn
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1712-1778 | 2.3e-06 | 21.5 | In-house | 53-124 (319) | alignment | ||
Range on Protein: 1712-1778
Range on HMM: 53-124/319.0
QGSNSYTNPSFTAGYHDKKA-FIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE-D---CCYPYWTGLSTH
. .. | . |. ||.| .. .| || ..|... |||... . . || |. | |. |
ddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketl
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1713-1911 | 3.9e-52 | 172.4 | In-house | 82-292 (298) | alignment | ||
Range on Protein: 1713-1911
Range on HMM: 82-292/298.0
GSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED----CCYPYWTG--LSTHDDFVVEIANEIKSNGYIERMLNV-----
| | || .|....|||..| |...| |||.|........|||| |. . || |.... |.. .. . .| | |.|
eesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkke
-ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTS
..|.| ||..| ||. || .. ..||.....| ||. | ||.|.||. | ||| .. .. ||. |.| ||||||| |..||..||||.| |||.
ekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvf
IYDVIDMYLQM
||... .|.
iyeavlealds
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1713-1913 | 1.2e-48 | 160.8 | In-house | 74-287 (319) | alignment | ||
Range on Protein: 1713-1913
Range on HMM: 74-287/319.0
GSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED----CCYPYWTGLS--THDDFVVEIANEIKSNGYIERMLN------
. | | || ||.....|| .|.|.||| |||.|. ....| .|||.. . . ||. . ..|.. .| . ..|| | |.
egsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkss
-VESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYT
||.|.| . | |.||...| .. ...|... .. . ..| ||.|||||. | | | .. ... ||. | |||.|||.. . .| .. | . |||.
evetRevkhfqyteWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYk
SIYDVIDMYLQMNK
||... .... .
fiyealleaveagd
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1713-1905 | 3.9e-40 | 132.5 | In-house | 55-262 (283) | alignment | ||
Range on Protein: 1713-1905
Range on HMM: 55-262/283.0
GSNSYTNPSFTA---GYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC----GEEDCCYPYWT--GLSTHDDFVVEIANEIKSNGYIERMLNVES
|..| | .| |...| .||||||...| .|||||. | |..||||| ... | || | . .| | . .| || .| . | .
esrdyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrv
R-----NVL--QLQVTDWpqdgVVREPRTVLQV---IDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVT
..| || || . .. ... .. || |.. ||.||||| .. |..|....| ... ..| |||||.| | .|. ...||
nssakstlllahyqvidW....leygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavq
TLEQYTSIYDVI
||.|| .....
tldqyklvhelv
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1713-1911 | 3.8e-36 | 119.6 | In-house | 55-270 (274) | alignment | ||
Range on Protein: 1713-1911
Range on HMM: 55-270/274.0
GSNSYTNPSFTAGYHD-KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG--EE--DCCYPYWTGLS------THDDFVVEIANEIKSNGYIERMLNV
|| | . ||. .||.. .| |. || |||.|| .|. |||| |. . | |. ...|. ... . .. |.| | | .
edssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvl
E----SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKI--GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTL
. .|.| |||| . ....|.|.....| . ... .||||||| . | |.. ..||.. | ..|.||||.... .| . | | |
kylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqts
EQYTSIYDVIDMYLQM
||| |. .. .||.
eqyelihralclylkr
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1713-1912 | 2.2e-34 | 113.7 | In-house | 46-267 (270) | alignment | ||
Range on Protein: 1713-1912
Range on HMM: 46-267/270.0
GSNSYTNPSFTAGYHD-KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYWTGLSTH----DDFVVEIA--NEIKSNGYIERMLNV
| | . .|... ||..| |..|...| ..||.||.. ||.||||. | . | ||. . . | .... .| |..||| . |..
sataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrl
E----SRNVLQLQVTDWPQDGVVREPR------TVLQVIDDV-IHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPG
| .|... . ..||..||.||. .|... .| ..... ..|..||||. | |.|. . |... . .. ||| .. ...|| ..
eekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRma
AVTTLEQYTSIYDVIDMYLQMN
| . |||. .| .. .| ..
lvqhpeqyeflykavveyaerr
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1713-1908 | 1.1e-29 | 98.2 | In-house | 55-258 (267) | alignment | ||
Range on Protein: 1713-1908
Range on HMM: 55-258/267.0
GSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC--GEED--CCYPYWTG-LSTHDDFVVEIANEIKSNGYIERMLNVESRNVL
. | | |. ||. |.|||. | |..|| ||...| |.||. ||.| .... .| | ..|..|| . | . | | |... .|
keeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirlfwPPkmgqakkyqdltvehslekeendyqiitlelkfknes
QLQVTDW--PQDGVVREPRTVLQVIDDVIHR-QQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDV
.|| . . . . . |. . .. . | . |. |.||.||| | ||| . . ||. | |||.|.|. . .|. ..| | |.|.| |...
ahnvtlyyykkwnintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihel
IDMY
. |
laey
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 1713-1903 | 9.2e-28 | 92.5 | In-house | 3-155 (172) | alignment | ||
Range on Protein: 1713-1903
Range on HMM: 3-155/172.0
GSNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEedccypywtglsthddfvveianeiksngyiERMLNVESRNVLQLQVT
... | | |. .|. . ||. | |. || |||.|. ......||.|... . ..|...|.. .
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...............................lydpellerlgiqylyl
DWPQDGVVrEPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLeqckaeG-VvDVFQVTKAVRKSKPGAVTTLEQYTSIYD
|| || .. .|.... . ..... ||||.|||| |.|.|. . . | . ..... . ||. .||||.. .|| .|.
pwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lgl.sleeavalvrekRpgavqnpsqyrflyy
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 1713-1909 | 2.6e-25 | 84.6 | In-house | 10-173 (176) | alignment | ||
Range on Protein: 1713-1909
Range on HMM: 10-173/176.0
GSNSYTNPSFTAGYHdkkaFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWTGLS---Thddfvveianeiksngyiermlnvesrn
.. .| |... .|.. .|. | |...| ||..|. .....|.|.|. | . |. || |
ldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi............................
vlQLQVTDWPQDGVVREpRTVLQVIDDVIHRQQKigGGPVVVHCSDTVSRSGVYCSVSigleQCKAEGVVDVFQVTKAVRKSKP-GAVTTLEQYTSIYDV
| ....|| || . .|.... . .... ||||.|||| ..|.|... .. | ..|... . ||. .| |||.| ||| .|..
..qylhlpwpDhgvpdl.elllellefirealke..ggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyef
IDMYL
. ..|
ellll
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1714-1911 | 7.5e-48 | 157.9 | In-house | 36-244 (250) | alignment | ||
Range on Protein: 1714-1911
Range on HMM: 36-244/250.0
SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG---EEDCCYPYWT--GLSTHDDFVVEIANEIKSNGYIERMLNVE------
| | || ||...||||..|.|...| |||.|....|...|||| .| . || . .. | |.. .. . |. | | .
esdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesektyhqywPvekaekyGdvtvsllskeefadytkrklklskakkad
SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIY
.| | ||. . || || .. ..||.....| ||..| .||.|.|| |.||| .. .. ||. | | |||||.| |..|| .|.||..|||| ..|
erivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvy
DVIDMYLQM
.| .|.
eiilkalds
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 1714-1917 | 2.4e-45 | 150.0 | In-house | 75-294 (307) | alignment | ||
Range on Protein: 1714-1917
Range on HMM: 75-294/307.0
SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWT--GLSTHDDFVVEIANEIKSNGYIERMLNVE-----
. .| | || ||..|| ||.|| |.|.|. |||.|| . .| |||| ... | ||. ..| .|....| | . ||.| |.|
dsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkee
------SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLE
||.|.| . | |. | . .|..|..|. | . ... .|.||||| |.|||.. .... |.|.||| ||.|...| .|. .. |. ||
sgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsle
QYTSIYDVIDMYLQMNKADDD
||. .| . | .. ..| |
qYvflyralldyssygdtded
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 1714-1911 | 1.9e-44 | 146.9 | In-house | 85-297 (330) | alignment | ||
Range on Protein: 1714-1911
Range on HMM: 85-297/330.0
SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG----EEDCCYPYW--TGLSTHDDFVVEIANEIKSNGYIERMLNVE-----
. | | || ||..|. || || | |.| |||.|| ..| ..|||| .|. |. || || |. . ||. .| .. | | . |.
esdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpda
-----SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGgPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQ
|| | |. | ||. || ||. .|... | . .|. .| |.||||| | |.| .. .. ||. |||..||||.. | .|. .| | |.||
trekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeq
YTSIYDVIDMYLQM
|. || |. |
yefiykvlleyyly
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 1714-1909 | 2.2e-44 | 147.1 | In-house | 36-243 (245) | alignment | ||
Range on Protein: 1714-1909
Range on HMM: 36-243/245.0
SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYW--TGLSTHDDFVVEIANEIKSNGYIERMLNVE-----
..| | |. ||. .. ||..| |...| |||.|. ......||||. ||. |..|| . |..||.|. .| . ..|. | |.|.
dsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgdd
-SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSI
||.|.... ..|| .|| ....|.... | . ... ..|||.||||. |.|.|... . . ||| ..|. |..... | .|. .||||.|..|| .
esrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrfl
YDVIDMYL
|... ..|
yeallell
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 1714-1910 | 4.6e-27 | 90.0 | In-house | 59-270 (273) | alignment | ||
Range on Protein: 1714-1910
Range on HMM: 59-270/273.0
SNSYTNPSFTAGY--HDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED----CCYPYWTG-----LSTHDDFVVEIANEIKSNGYIERMLNV-
. .| | |. .|. .|..| |. .|..|||.|. . |.. |.|. | . | || | .. . || . | .|. | |.|
eggyinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavk
-----ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQkiGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLE
|||.| .|. ..|| || ... .||.. | . |. ||.||||| . |||.. .. . |. . . .|| .. . .|. . | | | .
dsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqt..dagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkd
QYTSIYDVIDMYLQ
|| .| .| |.
qyifvykailevlk
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1714-1905 | 1.3e-26 | 87.9 | In-house | 72-232 (392) | alignment | ||
Range on Protein: 1714-1905
Range on HMM: 72-232/392.0
SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG--EEDccypywtglsthddfvveianeiksngyiermLNVESRNVLQLQV
. | | |. ... .||.| .|.| . |||.|. . .|..|.|. | | . | | | ..
dsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd................................kgddartvaqfhf
TDWPQDGVVREPRTVLQVIDDVIHRQQKIgGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVI
|.||...| . ..|..| .| . |...||| | |.|| |. . ..| .||||.. .|. .| | | |||. || .
tewPdkdvpkhtssllkfikevkadfGqy.thpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygav
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 1714-1911 | 1.5e-26 | 88.1 | In-house | 75-298 (300) | alignment | ||
Range on Protein: 1714-1911
Range on HMM: 75-298/300.0
SNSYTNPSFTAG--YHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGE----EDCCYPYWTGL------STHDDFVVEIANEIKSNGYIERMLNV
|. | | | .. .|.||.|.|.| .|||.|. . .|. |||| | . .. |. | ... | | .|. .| . |..
stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglkl
------ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDV---IH-RQQKI----GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKS
| |.|. || ||||..|| ..... |. ...| . .... ||.||||. | |.|| . . .. . . ..|. .| . .|.
khlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreq
KPGAVTTLEQYTSIYDVIDMYLQM
. | || ||. .|.|. ||.
rmllvqtlaqYkfvYkvlikylkn
|
|||||||||
| subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1714-1820 | 1.2e-08 | 29.3 | In-house | 12-127 (130) | alignment | ||
Range on Protein: 1714-1820
Range on HMM: 12-127/130.0
SNSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC--GEEDCCYPYWTGLS-THDDFVVEIAN-----EIKSNgYIER--MLNVES
| | | || . .. .| |. .|. |||||... | .|.| ||| .| | .| .| ... .||.. ..| ||
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveeedeywpdsePlewyeediivtltdrdefknikas.nleiesdlnesh
RNVLQLQVTDWPQDGVV
. . .|...|| ||
qaltmfqisnwpsdgtt
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 1714-1769 | 1.9e-07 | 25.1 | In-house | 74-132 (418) | alignment | ||
Range on Protein: 1714-1769
Range on HMM: 74-132/418.0
SNSYTNPSFTAGYHDkKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDCC----Y
. | | . | . | || .| |. || |||.|. . .. |||| | . |
gsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsresencrikcd
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1715-1904 | 3.3e-36 | 120.2 | In-house | 89-286 (319) | alignment | ||
Range on Protein: 1715-1904
Range on HMM: 89-286/319.0
NSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCgeEDCCYPYWT--GLSTHDDFVVEIANEIKSNGYIERMLNVES-------RN
| | || .|| |. .| || |..|| |||.|| .|..|.||.| .| | || . ... | |.. ... |. | ... |.
sdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt..kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirk
VLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGG-GPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDV
. | ||. || | ...... | | ..| . ..||||| | |.||| . . |.. | | |||... . .|. .. | | || ||
itqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysa
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1715-1904 | 4.3e-36 | 119.9 | In-house | 53-250 (284) | alignment | ||
Range on Protein: 1715-1904
Range on HMM: 53-250/284.0
NSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCgeEDCCYPYWT--GLSTHDDFVVEIANEIKSNGYIERMLNVES-------RN
| | || .|| |. .| .| |..|| |||.|| .|..|.||.| .| | || . ... | |.. .|. |. | ... |.
sdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt..kdkcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirk
VLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGG-GPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDV
. | ||. || | ...... | | ..| . ..||||| | |.||| . . |.. | | |||... . .|. .. | | || ||
irqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysa
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 1715-1912 | 1.9e-31 | 104.5 | In-house | 19-174 (182) | alignment | ||
Range on Protein: 1715-1912
Range on HMM: 19-174/182.0
NSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCgeedcCYPYWTglsthddfvveianeiksngyiermlNVESRNVLQLQVTDW
..| |... .|.. . ||..| |. .| ||..|. ......||.|. ...|| . . |...|.. . |
ldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.....eelywp..........................ellerlgiqylylpw
PQDGVVRePRTVLQVIDDVIHrqqkiGGGPVVVHCSDTVSRSGVYCSVSIGLEQckaeGvVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQMN
| .|| ....|. |..|.. ||||.|||| |.|.|... . ... | |..... | ||. .||.|.|..|| ..... ..|. .
pDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl....g.vsleeavklvrsrRpgmvitpnqyfflqlallellllk
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 1715-1910 | 2.1e-31 | 105.0 | In-house | 4-226 (272) | alignment | ||
Range on Protein: 1715-1910
Range on HMM: 4-226/272.0
NSYTNPSFTAGYHD---KKAFIIAQSPMENTARDFWKMiVDYKVSAIVMLCGEE----DCCYPYWTGLSTHDDFVVEIANEIKSNGYIERM---------
..| | .. ||. ..... .. |...||.|||.. ......||.|..|| . |..|| |. . ... . . . |.. .
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
------------LNVESRNVLQLQVTDWPQDGVVREPrtVLQVIDDVIHrqqkigGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVD--------VF
. |.| |..|. |||| .|| .|. .|.... . . ||||.|||| ..|.|... . . |.. .| .|| ..
yilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyle
QVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQ
.. . .|. |||| | ||| .|... .|
eaveelraqrpgavqteeqylflyeallellr
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1715-1905 | 1.6e-29 | 97.7 | In-house | 76-275 (439) | alignment | ||
Range on Protein: 1715-1905
Range on HMM: 76-275/439.0
NSYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDCcYPYWTGLS--THDDFVVEIANEIKSNGYIERMLNV--------ESR
| | . ||.|.| .| .| | ..|. |||..... |.. ||||. . | || . . | .| . .|. |. | ..| |
shyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlves.ykywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdtteker
NVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDV
|||.. . ||. | . ||. . . ..| |||||||| | |.| .. | ||| |.| ||. . | .|| . | .| || ||.
tvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiyna
I
.
v
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 1715-1903 | 3.7e-28 | 93.8 | In-house | 2-164 (174) | alignment | ||
Range on Protein: 1715-1903
Range on HMM: 2-164/174.0
NSYTNPSFTAGYHDKKAFIIAQSPMEntardFWKMIVDYKVSAIVMLCGEED----CCYPYWTGlsthddfvveianeiksngyierMLNVESRNVLQLQ
..| | |. ... . .|. | |.. ||.|. .......|||. |. |. || . . ..|...|..
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe.......................lredlerlgiqyl
VTDWPQDGVVREPRtVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKaEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYD
. || .|| . .|.... | . ... .||||.|||| |.|.|. . . | . . |..||.... ...|. .||.|.| .|| .|.
ylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 1715-1913 | 4.8e-20 | 68.0 | In-house | 72-284 (314) | alignment | ||
Range on Protein: 1715-1913
Range on HMM: 72-284/314.0
NSYTNPSFTAGYhdkKAFIIAQSPMENTARDF----------WKMIV--DYKVSAIVM---------------------LCGEEDCCypywtGLST----
.| | |. |. ..||..| |.|.| || |.|.. |..| ||| |.. .. |
sdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng.....neptaadl
---HddfvveianeiksngyiERM--LNVESRNVLQLQVTDWPQdGVVREPRTVLQVIdDVIHRQqkIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCkae
. |.. . .|..... ...| | . .. ..... ..|.. ||||.|||.. ..|.|... . . . ..
ellk.................eelydpelferlgikylripvpD.gsaplledfdefl.efieea..dkggpvlvHCkaGkgRtgtfvvaaylmkll...
GVvDVFQVTKAVRKSKP-----GAVTTLEQYTSIYDVIDMYLQMNK
|| .. .. . ||. | |.. .|||| |.... .||.. |
gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkflk
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1715-1774 | 2.6e-06 | 21.2 | In-house | 69-134 (303) | alignment | ||
Range on Protein: 1715-1774
Range on HMM: 69-134/303.0
NSYTNPSFTAGYHDKKAfIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE-------DCCYPYWTG
|| |. .||| |..| |. || |||.||.. || ...| . | .|
ssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqd
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 1716-1912 | 9.5e-43 | 141.9 | In-house | 52-275 (278) | alignment | ||
Range on Protein: 1716-1912
Range on HMM: 52-275/278.0
SYTNPSFTAGYhdKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWT--GLSTHDDFVVEIANEIKSNGYIERMLNVES------
| | |. || .|.||..| |...|. |||.|. ......||||..... |..|| | |..||.|.. .| . |. |.|.|.
dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltvere
----RNVLQLQVTDWPQDGVVREP--RTVLQVIDDVIHRQQK------------IGGGPVVVHCSDTVSRSGVYCSVSIGLEQCkaEGVVDVFQVTKAVR
|.| .|. . || || .| . .|.... . ..... .||||.|||| |.|.|... . . ||.. ||.||.... | .|
dlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelr
KSKPG-AVTTLEQYTSIYDVIDMYLQMN
. .|| ||..|||| .|... ..|...
sqRpglavqnleqyrflyefllelllrg
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 1716-1904 | 1.5e-21 | 72.0 | In-house | 4-148 (151) | alignment | ||
Range on Protein: 1716-1904
Range on HMM: 4-148/151.0
SYTNPSFTAGYhdkkaFIIAQSPMEntarDFWKMIVDYKVSAIVMLCG--EEDCCYPYWTGLSthddfvveianeiksngyiermlnvesRNVLQLQVTD
.|.| |. |. ... . |.. ||.... ......||.|.. | . |. |.. |. ..||.....|
dyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeergycpeylpelg...........................ievlhipild
WPQDGVVREPRTVLQVIDDVIHrqqkIGGGPVVVHCSDTVSRSGVYCSVSIGLEQckaegvVDVFQVTKAVRKSKPGAVTTLEQYTSIYDV
|| |. . .||.... ... ..|||.|||| ..|.|. . . . |.. |..... . .|.. ||.|.. .|. .. .
wpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlfa
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1716-1763 | 6.7e-08 | 26.6 | In-house | 74-121 (305) | alignment | ||
Range on Protein: 1716-1763
Range on HMM: 74-121/305.0
SYTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCG
| . . . | || .|.|.|.| ||| | .. || || |||
eyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcn
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1717-1907 | 1.1e-09 | 32.4 | In-house | 69-274 (312) | alignment | ||
Range on Protein: 1717-1907
Range on HMM: 69-274/312.0
YTNPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGE----EDCCYPYWTG---LSTHDDFV--VEIANEI----KSNGYI-ERMLNVE
| | . |...|.|.|||. ||.. . ..|..||| . | | . . .| | || ||. | |.|.|
yihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrvyteycteieiggkskdkithrvlkvv
SRN------VLQLQVTDWPQDGVVREPRTVLQVIDDViHRQQKigggPVVVHCSDTVSRSGVYC---SVSIGLEQCKAEGVVDVFQVtkaVRKSKPGAVT
. . . | . ||. |. | |... | ....| ||. ||| | |.| . |. | . . . | |.| . .|| . .|
vkatgqesklnhyqwaswpdhgmpdscdtalrllsav.kkdkk....pviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvl...lrkdrarsvr
TLEQYTSIYDVIDM
.. || ..
vfpqyvyalrcvle
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 1718-1913 | 4e-35 | 116.3 | In-house | 84-301 (306) | alignment | ||
Range on Protein: 1718-1913
Range on HMM: 84-301/306.0
TNPSFTA--GYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED----CCYPYWTGLSTHDDF---VVEIANEIKSNGYIERMLNVE------
| .. .|..| .| .|.| |||.|... . |||. | . |..|| ...... |. .| . . || | |.|.
inanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkk
-SRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIG---GGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGV---VDVFQVTKAVRKSKPGAVTTL
.|.| |.. ..||. || ..| .||. ..|| ..|... ||.|||||. . | | . . | |.. . .|. .|. .. | ||. . | | |
eerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqte
EQYTSIYDVIDMYLQMNK
.|| .| .| .|.. .|
qqykfvykaikkyietkk
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1718-1798 | 1.1e-08 | 29.2 | In-house | 100-175 (350) | alignment | ||
Range on Protein: 1718-1798
Range on HMM: 100-175/350.0
TNPSFtagyhdkkAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED----CCYPYWTGLSThDDFVVEIANEIKSNGYIERM
||.| .| .|.|. .| ||.|.|. || |..| . . || || .| ||. | .|. .. . |. .
inpdf........kYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegsy.dditvklaskwenimginds
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1719-1909 | 1e-16 | 55.8 | In-house | 71-277 (307) | alignment | ||
Range on Protein: 1719-1909
Range on HMM: 71-277/307.0
NPSFTAGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEED----CCYPYWTGLSTHDDFVVEIANEIKSNG-------YIERMLNV------
. . | || || |.||| .|| |... || ...||| . | || .| .| | . | ..||
hanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvd
---ESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQkigggPVVVHCSDTVSRSGVYCSVSIGLEQ-CKAEGVVDVFQVTKAVRKSKPGAVTTLEQ
.|| . .|| ..||. || . | . ... | . ||||||| | ||| ..|. .. . . |. .. . .|. .. |. | |
waqksrtiqhlqwenwpdrgvpqinltainlleavrydtn.....pvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaq
YTSIYDVIDMYL
| .. |. |.
ylylhrvlleyf
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 1724-1903 | 2.4e-24 | 81.2 | In-house | 3-144 (152) | alignment | ||
Range on Protein: 1724-1903
Range on HMM: 3-144/152.0
AGYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDC----CYPYWtglsthddfvveianeiksngyiermlnvesrnvlQLQVTDWPQDGV
||. ...||..| |..||. |||.|. ......||||. ... |. |. | . . || .||
dgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...................................qylhlpwpDhgv
VREPRTVLQVIDDVIHRqQKIGGGPVVVHCSDTVSRSGVYCSVSIGLeqckaeGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYD
. .|.... . .. .. ||||.|||| |.|.|... . | |..... . ||. .||||.. .|. .|.
pdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1725-1762 | 8.3e-07 | 23.3 | In-house | 77-114 (288) | alignment | ||
Range on Protein: 1725-1762
Range on HMM: 77-114/288.0
GYHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC
. |. .| ||.|.. | .|||... | |||||
sakykrrlicaqaPlngtieelWkmllesdveyivmlc
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1726-1906 | 2.2e-11 | 37.9 | In-house | 90-287 (310) | alignment | ||
Range on Protein: 1726-1906
Range on HMM: 90-287/310.0
YHDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGE--ED--CCYPYWTGLSTHDDF-VVEIANEIKSNGY-----------------IERMLNVES
. ...|| .| |.. | |||.|| . . .|..|| | | || | . . .. ..| .| |. |..
nylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlke
RNVLQLQVTDWPQDGVVREP-RTVLQVIddviHRQqkIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIY
| .. .||. || | || | . | . ||.||||| . | .| ... . ... . ||. .| ..||. . | ||. |
lrvslikwpnwpdrgvpdekchtvpqrl....laq..vrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliid
DVID
|
rvri
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1727-1909 | 7.6e-09 | 29.9 | In-house | 72-270 (285) | alignment | ||
Range on Protein: 1727-1909
Range on HMM: 72-270/285.0
HDKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC-----GEEDCCYPYWTGLSTHDDFV-VEIA-NEIK---SNGYIERMLNV---E-----SRNVLQ
.|. ..| .| |. .| |||.|| . |.. ..||| | | |. | | | ||. | | | | | | | . .
kdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtilnaltvintedasseplymnh
LQVTDWPQDGVVREPRTVLQVIDDVIHRQQKigGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMY
.|| ||.. . | .... | . . | |..|||| | |. . . . . ...... . .| . || . |. .| |. |
vqvpwwpdqlapedarpmielykwvkkvnpk..ekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmey
L
.
f
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1728-1912 | 3.2e-15 | 51.0 | In-house | 58-262 (290) | alignment | ||
Range on Protein: 1728-1912
Range on HMM: 58-262/290.0
DKKAFIIAQSPMENT-------ARDFWKMIVDYKVSAIVMLCGEED---------CC--YPYWTG-LSTHDDFVVEIANEIKSNGYIERMLNVESRNVLQ
. ..|. ||| |.. .|| |. . || .|||| |. | .| | . ... |. . .| .. ..| | |. . .
nglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeee
L-----QVTDWPQDGVVREPRTVLQVIDDVIHRQqkiggGPVVVHCSDTVSRSGVYCSVSIGLEQCK-AEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIY
. .. .| . | ....|.|..|. | .. ||.||| | .||| . .. .| .| | . .| ||.|| . |.|. .... .
ftvtHsllkgWnklnvqedtktllsliqkvkask.....tpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvd
DVIDMYLQMN
.| ....
agivllaiev
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1728-1909 | 3.7e-14 | 47.1 | In-house | 94-289 (305) | alignment | ||
Range on Protein: 1728-1909
Range on HMM: 94-289/305.0
DKKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE----DCCYPYWTG-----LSTHDDFVVEIANEIKS---NGYIE-RMLNVES-----RNVLQL
.| || || |...| .|| |... || ||||| | || |. . ||| | . |. .||. | .|
pekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhl
QVTDWPQDGVVREPRTVLQVIDDVihRQQKIgggPVVVHCSDTVSRSGVYCSVSIGLEQCKA-EGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMY
| |.||. || | |... . | |. |.||||| . |.| .. ||. . . .. ||.| . .. . || |. |. |
qwtewpdrgvppckltslellsai..rgskv...pivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlny
L
.
f
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1729-1905 | 9.5e-20 | 65.4 | In-house | 93-279 (290) | alignment | ||
Range on Protein: 1729-1905
Range on HMM: 93-279/290.0
KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGE----EDCCYPYWT---G-LSTHDDFVVEIANE-IKSNGYIERMLNVES------RNVLQLQVTD
| ||..| ....|. |.|.|... ||.|||||| | .|. | | .. | ..| | . | ..| | . |..
kamfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkiks
WPQDGVVREPRTVLQVIDDVihRQQkigGGPVVVHCSDTVSRSGVYCSVSIGLeQCKAEG-VVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVI
||. | ..|... . |. |||||||| . |.| . .. .|| |. .| .|. .. .|.|.|. ..| || . ...
wpdksvalstlallrtlril..rka...sGpvvvhcsaGiGrtGtfvaievgl.qilldGkeldlldlvralrnsrlnsvqvdiqylalveil
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1729-1898 | 2e-15 | 51.3 | In-house | 89-270 (301) | alignment | ||
Range on Protein: 1729-1898
Range on HMM: 89-270/301.0
KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGE----EDCCYPYWTGLSTH----DDFVVEIAN--EIKSNGYIERMLNVE-------SRNVLQLQV
. ||..|.|..||. ||| |.| |.| ||||. . |. | | . .. . | ..| | | .. ..| |.|| .| |. |
phrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqy
TDWPQDGVVREPRTVLQVIDdVIHRQQKigggPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQY
..|.. || . . .... .. . .| |.|||||. . || . . . . .|. ... . | .|. . .| | .|
sewtdrgvPkshaelfdlme.lvkksek....PivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsql
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1729-1904 | 1.5e-12 | 42.1 | In-house | 4-199 (199) | alignment | ||
Range on Protein: 1729-1904
Range on HMM: 4-199/199.0
KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE---DCCYP-YWTG----LSTHDDFVVEIANEI-KSNGYIERML-------NVESRNVLQLQVT
.. .| .| |. .| |||.|. . |||. .. .. || || . . . | |.. | .. .|.. . | |
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
DWPQDGVVREPRTVLQVI--DDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCK--AEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDV
| . | |. .| .. .. ||.||||| .||. .. ||. . |||.|.|.| .|... | ...|..| ||.|
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1729-1904 | 1.5e-12 | 42.2 | In-house | 3-198 (198) | alignment | ||
Range on Protein: 1729-1904
Range on HMM: 3-198/198.0
KKAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE---DCCYP-YWTG----LSTHDDFVVEIANEI-KSNGYIERML-------NVESRNVLQLQVT
.. .| .| |. .| |||.|. . |||. .. .. || || . . . | |.. | .. .|.. . | |
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
DWPQDGVVREPRTVLQVI--DDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCK--AEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDV
| . | |. .| .. .. ||.||||| .||. .. ||. . |||.|.|.| .|... | ...|..| ||.|
swkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyqv
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 1730-1905 | 1.5e-27 | 91.3 | In-house | 84-271 (280) | alignment | ||
Range on Protein: 1730-1905
Range on HMM: 84-271/280.0
KAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGE----EDCCYPYWT---GLSTHDDFVVEIANEIKSNGYIERMLNVE------SRNVLQLQVTDWPQ
. .|..| |...|| |||.|. . |.| |||| |. || ... .| |.. .| ... |. | | .. .|..|||| ..||.
nryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpd
DGVVREPRTVLQVIDDViHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVI
|| .. .|.... | ..... ||||||| . |.||. . . | |. | . .. . .| . | | .||. . . |
hgvPddsadflefverv.rklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeai
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1730-1905 | 6.4e-16 | 53.1 | In-house | 76-291 (297) | alignment | ||
Range on Protein: 1730-1905
Range on HMM: 76-291/297.0
KAFIIAQSPMENTARDFWKMIVDYKVSAIVMLC----GEEDCCYPYWTG----LSTHDDFVVEIANEIKSNgYI-----E--RMLNVESRNVLQLQVTDW
.|.|| |...| |||..... | .|||.. . | |.||| . |.||| . . . | . ||| | | |
lkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsde.fdrviltelqliyrsesrvvrhvqflsw
PQDGVVR----EPR-------------TVLQVID---DVI------HRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSK
|. || | .| ... .. | .. ...|||| | |||| . |.. . . . || . . .|. .
pdhGvpsdledlvrfqaqvcscciavpmmlalvemftamvflqleslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqr
PGAVTTLEQYTSIYDVI
. | ||||.. .||..
arlvqtleqfellydav
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 1730-1910 | 2.2e-13 | 44.6 | In-house | 83-271 (307) | alignment | ||
Range on Protein: 1730-1910
Range on HMM: 83-271/307.0
KAFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEE--DCCYPYWTGLSTHDDFVVEIANEIKSNGYI---ERM-----LNVESRNVLQLQVTDWPQDgv
||.||.|. || |||.|. .| |||| . | || .. .| . .|.. . . . |.. . .. . | |
nefilaqaplkntvddfwrmvfqeevqyivmltsrkeserceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqgd..
VREPRTVLQVIDdvIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVV--DVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQ
|.. | . . |. . ||||.. . ||.... .. | | . .. | . . .|. .. .| . .| .| .. ....
vnnssdvysplr..vlrklrnlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffr
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 1731-1905 | 2e-29 | 97.3 | In-house | 84-276 (288) | alignment | ||
Range on Protein: 1731-1905
Range on HMM: 84-276/288.0
AFIIAQSPMENTARDFWKMIVDYKVSAIVMLCGEEDCCYP----YWTG----LSTHDDFVVEIANEIKSNGYIERMLNVES------RNVLQLQVTDWPQ
||..|.|...|. |||.|... |.| |||| .|. | || ...|. | . .. ... ..||.|..| ..| ||.| ||.
dfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpe
DGVVREPRTVLQVIDDVIH---RQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQC-KAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVI
|| | |.||..| | . .|. |.||||| | |.||.. | ... | .|..|. || . .|. . | . ||. |...
lGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeav
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 1732-1912 | 3e-17 | 58.3 | In-house | 30-174 (178) | alignment | ||
Range on Protein: 1732-1912
Range on HMM: 30-174/178.0
FIIAQSPMentaRDFWKMIVDYKVSAIVMLCGEEDCC----YPYWTGLSThddfvveianeiksngyiermlnvesrnvL---QLQVTDWPQDGVVREPR
..... |. |..... ......||.|..| . .||| . .. . |.. . . .
lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag.............................iqylhipipDhgvpdllehfl
TVLqvidDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQckaeGVvDVFQVTKAVRKSKPgAVTTLEQYTSIYDVIDMYLQMN
.. . |.. .. ||||.|||| |.|||. . . ... |. ..... . ||. .| .|.. .|. .|.. ..|...
efv....efieealdekggpvlVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgqlrqLyefelrllkes
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 1748-1903 | 4.6e-13 | 44.6 | In-house | 23-139 (144) | alignment | ||
Range on Protein: 1748-1903
Range on HMM: 23-139/144.0
KMIVDYKVSAIVMLCGEEDCCYPYWTglsthddfvveianeiksngyiermlnvesrnVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQkiGGGPVVV
... ........ |. | . .. . ..|.. ..|| || . .|.... . . .. ||||.|
ellkklgittvinlteeyepeflere................................giqylhlpwpDhgvpdllellleflefieeale..eggpvlV
HCSDTVSRSGVYCSVSigleQCKAEGvVDVFQVTKAVRKSKPGAVTTLEQYTSIYD
||| |.|.|... .| .| ...... . ||. ||||.. .|. ...
HCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpgavpnpgqlrfLle
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 1761-1908 | 2.6e-14 | 48.6 | In-house | 36-142 (145) | alignment | ||
Range on Protein: 1761-1908
Range on HMM: 36-142/145.0
LcgeedccypywtglsthddfvveianeiksngyiERMLNVESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKigGGPVVVHCSDTVSRSGVYC
| ..|. ..|...|.. ..|| || ....|.... . . ... ||||.|||| |.|.|...
l..................................tselellerlgiqylylpwpDhgvpdllellleflefieealke..ggpvlVHCsaGvgRtgtlv
svsiGLEQCKAEGvVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMY
.. .. .| |..... . ||. ||||.. .|. .|... ..
....aaylmlllg.vsleealelvrsqrpgavpnpgqlrflyefelel
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1778-1905 | 1.9e-18 | 61.0 | In-house | 61-190 (440) | alignment | ||
Range on Protein: 1778-1905
Range on HMM: 61-190/440.0
HDDFVVEIANEIKSNGYIER-MLN-VESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVV
| ..| . . .. ||. ..| .||| . | . ||. || . ||..|.|| . |.| | ||..|||| ..|.|| .| | ..| .
hsrvmleevkgvpdsdyinasyingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqi
DVFQVTKAVRKSKPGAVTTLEQYTSIYDVI
|.| . ...|...| | | |||. .....
difsfinsmrnnrpqmvqtpeqyafvheav
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 1795-1866 | 7e-06 | 20.0 | In-house | 177-253 (418) | alignment | ||
Range on Protein: 1795-1866
Range on HMM: 177-253/418.0
IERMLNVESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIG-----GGPVVVHCSDTVSRSGVYCSVSIGL
| .. |.|.. | | ||. . . . |.. . ||..| |..|||| | |.| .|. | .
irltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimm
|
|||||||||
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1801-1902 | 1.1e-10 | 35.4 | In-house | 185-281 (302) | alignment | ||
Range on Protein: 1801-1902
Range on HMM: 185-281/302.0
VESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKigggpVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTS
. | |. . ||. | .|. | |... ... |.|||| | |.| .. |.. |. . | |. .. . ||. . ||| . .| .
kvkktvdilafsawpdhGapkeaytaldilkfcesykkn.....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliy
IY
.
ll
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1801-1917 | 7.7e-08 | 26.4 | In-house | 183-295 (305) | alignment | ||
Range on Protein: 1801-1917
Range on HMM: 183-295/305.0
VESRNVLQLQVTDWPQDGVVREPRTVLQVIDDVihRQQKiggGPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVV-DVFQVTKAVRKSKPGAVTTLEQYT
..| | . |||. || ..|... . | | ||.||||| . |.| . |.| | .. | .. . .|. . .. | .||
ekarkvthyhwidwpdrgvpaadlailelleka..rpsk...gpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqyl
SIYDVIDMYLQMNKADDD
...|| |.. .| |.
fvhqvilnyfrkkkllde
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1804-1911 | 6.7e-06 | 19.6 | In-house | 218-346 (349) | alignment | ||
Range on Protein: 1804-1911
Range on HMM: 218-346/349.0
RNVLQLQVTDWPQDGVVREPRTVLQV-------IDDVIHRQ--QKIGGGPVVVHCSDTVSRSGVYCSVSIGLE--QCKAEGV--V--------DVFQVTK
.||||| .|. ... .| ..|| ||| |. .. ...|||| |.||.. . . |. . . . .. .
yellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivn
AVRKSKPGAVTTLEQYTSIYDVIDMYLQM
.|| . | | |. ||. . |...
elrkqrismvqnlaqfiaiyealLkyfal
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1805-1913 | 9.9e-07 | 22.8 | In-house | 216-348 (350) | alignment | ||
Range on Protein: 1805-1913
Range on HMM: 216-348/350.0
NVLQLQVTDWPQDGVVREPRTVLQVID---DVIH----R--QQKIGGGPVVVHCSDTVSRSGVYCSVSIGLEQ------C---------KAEgVVD-VFQ
|.|||| |. ... .|. .||... |.| . .. . |..|||| | | |..... |.. |. . | ...
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaak.trDlisi
VTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQMNK
. . .|| . | .|.|. ||. . | ...|
ivnelrkqrismvqnldqfifiYeallfyfaLrk
|
|||||||||
| PTPc_DSPc_SM00012 | 1806-1905 | 7.5e-24 | 79.3 | In-house | 2-103 (105) | alignment | |||
Range on Protein: 1806-1905
Range on HMM: 2-103/105.0
VLQLQVTDWPQDGVVREPRTVLQVIDDVIHRQQKIG-GGPVVVHCSDTVSRSGVYCSVSIGLEQCKAE-GVVDVFQVTKAVRKSKPGAVTTLEQYTSIYD
| ....|.||. || .|. .|.....| . ..|.. ..|||||||. |.|.|... ..| |.|...| . ||.||. |..||..||.|.|.||| .|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
VI
..
al
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1806-1913 | 2.3e-08 | 28.4 | In-house | 173-275 (288) | alignment | ||
Range on Protein: 1806-1913
Range on HMM: 173-275/288.0
VLQLQVTDWPQDGVVREPRTVLQVIDDViHRQQKigggPVVVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVI
| .| . .|..||| . . |.... . . || |.|||.| | |.| . | ||. . . . . .. . |... |..| || .. ..
vkilhlleWdddgvPenylsplrllevl.kslqk....PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcv
DMYLQMNK
.| . |
leelllkk
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1841-1909 | 1.2e-11 | 38.9 | In-house | 246-315 (319) | alignment | ||
Range on Protein: 1841-1909
Range on HMM: 246-315/319.0
GGGPVVVHCSDTVSRSGVYCSVSIGLEQCKAE-GVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYL
||.|||||| | |.|. . | ... . ||. |. ||. . || | ||| || |. .|
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1846-1909 | 7.4e-08 | 26.7 | In-house | 2-65 (69) | alignment | ||
Range on Protein: 1846-1909
Range on HMM: 2-65/69.0
VVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYL
||||| |.| . .. . . . |.| .||.| . .|| .| | .| |.| . |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1846-1911 | 2.3e-07 | 25.1 | In-house | 1-66 (69) | alignment | ||
Range on Protein: 1846-1911
Range on HMM: 1-66/69.0
VVHCSDTVSRSGVYCSVSIGLEQCKAEGVVDVFQVTKAVRKSKPGAVTTLEQYTSIYDVIDMYLQM
||||| |.| . .. . . . |.| .||.| . .|| .| | ..| |.| . |..
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealkl
|
|||||||||
| BolA | BolA-like protein | 1968-2043 | 9.5e-30 | 89.0 | Pfam-A | 1-76 (76) | alignment | ||
Range on Protein: 1968-2043
Range on HMM: 1-76/76.0
KLNESMKPQYLKVINESYKHAVPKGSETHFNIIVVSEKFESMPLLQRHRLINSILEHELQTGVHALSIQARTVVQW
||.....|. |.|..||.|||.....|.||....|||.|| . ...||||....|..||..|.||||....| .|
kleaalapeelevedeshkHaghaageshfkvvivseaFegksrvkRhrlVyalLkeelkegiHALslktytpeew
|
|||||||||