Gene PTPRD-7 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRD
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP128_AA protein Get Run
AqueP128_AA_1900-2009 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
I-set Immunoglobulin I-set domain 35-91 1.3e-06 20.1 Pfam-A 9-74 (90) alignment 
Range on Protein: 35-91
Range on HMM: 9-74/90.0
EARLSVGDSVVLECNCESD------WKQNEDNIINDTRHFITSRN---TLNILAVRSTDSGNYTCG
..  |.|.|| |||. | .      |.... .. .. |. .| ..   || |  |.. |.|.||| 
dvevseGesvelectveGepepsvsWakdgselkssqrvkvtveeaeytLtIsnvevsDeGkYtck
I-set Immunoglobulin I-set domain 138-188 2.3e-06 19.3 Pfam-A 28-77 (90) alignment 
Range on Protein: 138-188
Range on HMM: 28-77/90.0
SVLNISWFHNGTYIPTNNITRNDEEYlYISTLQLPSVNDANSGEYACVANV
  ...||...|. . ...  . ..|   ..|| . .|. ...|.| |.|..
pepsvsWakdgselkssqrvkvtvee.aeytLtIsnvevsDeGkYtckatn
Ig_3 Immunoglobulin domain 284-353 2.1e-06 19.9 Pfam-A 2-75 (75) alignment 
Range on Protein: 284-353
Range on HMM: 2-75/75.0
PNVTISGNYTSLRVGSsTDIKCETTPSIPNAVIEWQ------DVSSFNSYSYENGLTIDPVLlSDDNKTFTCVVSS
| ...| . |   .|.   . |... . |.. | |.      . .| .|.|.|. ||| .|  |.|. |.|||.|.
Pvisvspsptvtsggn.vtLtCsaeggpppptisWyietppelqgsegssssestLtissvt.sedsGtYtCvasN
Ig_2 Immunoglobulin domain 488-566 5.6e-07 21.5 Pfam-A 15-77 (80) alignment 
Range on Protein: 488-566
Range on HMM: 15-77/80.0
STVNIECIIIlntpvgpGI-QPTVTWYHDATDITlSGsllRNNdivfisvLTINSIQVSDAGVYQCNAGIDS-NVTTESIS
..|.. | .        |  .|.|.||.| . .. ..   .|.       | |......|.|.|.| |  ..   ...|. 
envtLtCqap.......gnptpkvqwykdgeels.qs...qna.......lfipnvsaedsGtYtCrasnsegskqsnsve
I-set Immunoglobulin I-set domain 507-567 3.2e-08 25.3 Pfam-A 29-88 (90) alignment 
Range on Protein: 507-567
Range on HMM: 29-88/90.0
QPTVTWYHDATDITLSGSLLRNNDIvFISVLTINSIQVSDAGVYQCNAGIDSNVTTESISV
.|.|.|..| .... | ..  ...   .. |||....|||.| |.|.|   .   ......
epsvsWakdgselkssqrvkvtvee.aeytLtIsnvevsDeGkYtckatnsagkaeakaeL
Ig_3 Immunoglobulin domain 668-749 9e-09 27.4 Pfam-A 7-74 (75) alignment 
Range on Protein: 668-749
Range on HMM: 7-74/75.0
LPTSIVSVDINstVELTCTISLNTGigpdtsFISHYWYqyrtdiSDRSTQLMISGDSKSLVTTLNITNIRPSDAGEYQCRAS
 | ..|....|  |.|||..  . .        ...||       . . .|  |..|.|  .||.|..  ..| | |.| ||
spsptvtsggn..vtLtCsaeggpp......pptisWy......ietppelqgsegssssestLtissvtsedsGtYtCvas
Ig_2 Immunoglobulin domain 671-752 1.1e-07 23.8 Pfam-A 8-68 (80) alignment 
Range on Protein: 671-752
Range on HMM: 8-68/80.0
SiVSVDINSTVELTCTISlntgiG-PDTSFIshyWYQYRTDISDRSTQlmisgdskslvttLNITNIRPSDAGEYQCRASIDG
. ..|. ...| |||...     | |.....   ||.  . .| .  .             | | |. ..|.| |.|||| ..
p.tvvtegenvtLtCqap.....gnptpkvq...wykdgeelsqsqna.............lfipnvsaedsGtYtCrasnse
I-set Immunoglobulin I-set domain 671-749 1.1e-06 20.3 Pfam-A 8-76 (90) alignment 
Range on Protein: 671-749
Range on HMM: 8-76/90.0
SIVSVDINSTVELTCTISlntGIgPDTSFiShyWYQYRTDISDrSTQLMISGDSksLVTTLNITNIRPSDAGEYQCRAS
. | | ....|||.||..   |  |. |. |  |..  ....  | .. .. ..    .|| |.|...||.|.|.|.|.
kdvevseGesvelectve...Ge.pepsv.s..Wakdgselks.sqrvkvtvee..aeytLtIsnvevsDeGkYtckat
V-set Immunoglobulin V-set domain 671-749 1.5e-06 19.0 Pfam-A 9-99 (114) alignment 
Range on Protein: 671-749
Range on HMM: 9-99/114.0
SIVSVDINSTVELTCTISlntgigPDTSFISHYWYQYRT-----DIS-------------DRSTQLMISGDSKSLVTTLNITNIRPSDAGEYQCRAS
. |.|  . .|.|.|. |      . ... | |||. .|      |                |    .|... .   .|.|.|.|..| | |.|..|
rpvtvaeGgsvtLpCfys......ssensqsiyWykqktgskpeliiryvaetnnskvgesfsgrvtlssngsksdfsLtiqnlrleDsGtYtCavs
Ig_2 Immunoglobulin domain 1109-1188 4.2e-08 25.1 Pfam-A 7-69 (80) alignment 
Range on Protein: 1109-1188
Range on HMM: 7-69/80.0
IPdeQYYDVGSNVTLTCSVNypptD----ShidvstslnISLFIGnDSLIRQSSKNIITyelNNLQLHDATLYTCSYfiSSDSG
 |  .... |.||||||...    .    .         ...  . .... || .....   .|....|.  |||..  | ..|
pp..tvvtegenvtLtCqap....gnptpk.........vqwykd.geelsqsqnalfi...pnvsaedsGtYtCra..snseg
fn3 Fibronectin type III domain 1425-1513 3.7e-14 45.8 Pfam-A 3-84 (85) alignment 
Range on Protein: 1425-1513
Range on HMM: 3-84/85.0
PLKFEAYNITAYEMTFTWLPPLecFRNGDIIKYSLSCSFNNATHsdiqqSLQHQIISKRENRFTLHNLYPFTNYTCHLAAANGIGEGPA
|  . . ..|. ..|..| ||    ..|.| .|.. ..  . ..       ... ... ....||..| | |.|.. ..| || ||||.
PenlsvsevtstsltlsWsppk..dgggpitgYeveyrekggge.....ewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
fn3 Fibronectin type III domain 1527-1603 2.9e-14 46.1 Pfam-A 1-84 (85) alignment 
Range on Protein: 1527-1603
Range on HMM: 1-84/85.0
SEPENLTIISTSSSSLVLTWSKPIQPNGIIVKYTINCSSD-----IFENETIDNT--VVLNGLVPYTNYTCSVSAHTRIGVGPA
|.||||......|.||.|.||.| ...| |..|.. ....       |  .  .|  |.|.|| |.|.|...| |... | ||.
saPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
fn3 Fibronectin type III domain 1711-1786 1.6e-07 24.5 Pfam-A 3-82 (85) alignment 
Range on Protein: 1711-1786
Range on HMM: 3-82/85.0
PGNVTAVWINSTTVKVTWLPLTlaKARGFITRYSV-YA--GNTG-IANVSNDSSI--AYIDSLNPMLQYSISVSASTKVGES
|.|...  ..||.. ..| | .  . .| ||.|.| |.  |...   .......   . .  |.|  .|...| | ...||.
PenlsvsevtstsltlsWsppk..dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngageg
subfamily_PTPRD_pd Subfamily PTPRD 1888-2007 2.3e-34 114.0 In-house 3-127 (564) alignment 
Range on Protein: 1888-2007
Range on HMM: 3-127/564.0
QRIKVNEFPSFVSRSK----RSIEYEFEEIERISPIKA-TSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKN
. |.|.|....| . |     ..| |...||. .  .  ..  . | | ||.......| . | ||. |..|.| |||||.||||....|||||||||..
kpipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlae

TIGHFWQMIIEYKLPTIVMLTKVFE
||  ||.|. |..  |||||||. |
tiedFWRmvweqnsstiVmltkleE
subfamily_PTPRB_pd Subfamily PTPRB 1888-2008 4.7e-30 99.6 In-house 5-131 (293) alignment 
Range on Protein: 1888-2008
Range on HMM: 5-131/293.0
QRIKVNEFPSFVSRSKRSIEY----EFEEIERISPIKAT--SIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLK
. ||...| ..|.. |.  ..    |.||.. .   .|.  .  ..|.| ||.... |.| . | |.. ..|..| ||||.||.||. .. .||||||| 
kpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlp

NTIGHFWQMIIEYKLPTIVMLTKVFEG
.|. .||.|. | |  .|||||...|.
etvddfWrmvwekkssiivmltqlvek
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 1888-2008 8.8e-22 72.3 In-house 1-124 (315) alignment 
Range on Protein: 1888-2008
Range on HMM: 1-124/315.0
QRIKVNEFPSFVSRSKRSIE--YEFEEIERISPIKATSI-GSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTI
| | | .||.|| . ...     || ..    . . ..   . |   ||.... |.| . | |   ... || ||||||| ...  .||||.||||| ..
qpipvaqfpafvnknrhtalfseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasv

GHFWQMIIEYKLPTIVMLTKVFEG
  ||.|....|  ||||.||  ||
ddfwrmvlqekvttivmvtkkqeg
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 1888-2008 1.5e-20 68.5 In-house 8-129 (297) alignment 
Range on Protein: 1888-2008
Range on HMM: 8-129/297.0
QRIKVNEFPSFVSRSkRSIEYEFEEIERI--SPIK-ATSIGSK-NAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRknAYIATQGPLKNT
. | . .|...| .. |. ... ||.  .  . |. .|    | |   .|.... |.| . | |   ... || |.|||.. |..    .|.|| | |.|
rpiplsdfatlvqkn.rhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkat

IGHFWQMIIEYKLPTIVMLTKVFEG
.  ||.|.....  |||||..  |.
vadfWamvldeqvstivmlnddner
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 1888-2009 2.2e-20 67.5 In-house 2-126 (392) alignment 
Range on Protein: 1888-2009
Range on HMM: 2-126/392.0
QRIKVNEFPSFVSRSKRSIEY--EFEEIERiSPIKATSIGSK--NAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNT
| | | .||.|| . ..|  .  || ..    .|  .... |  |   ||.... |.| . | |   .   || |.|||||.... ..||||.|||   .
qpipvaqfpafveknrhsalffeefhdlpg.pdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaas

IGHFWQMIIEYKLPTIVMLTKVFEGN
.  ||.|. . .  ||.|.||. ||.
lddfwrmvfqenvttiamvtklkegd
subfamily_PTPRG_pd Subfamily PTPRG 1891-2007 1.2e-24 81.4 In-house 2-127 (563) alignment 
Range on Protein: 1891-2007
Range on HMM: 2-127/563.0
KVNEFPSFVS----RSKRSIEYEFEEIERISPIK----ATSIGSKNAAFNRFEDVCPFDDNIVPLSTSE-KEEDSIYINASYIDGYQRKNAYIATQGPLK
.|.|| . |.     ..  .. |||.... .  |     .|   .|   ||  .. ..|   | ||    |...  ||||.||||||...|.||||||||
pvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplk

NTIGHFWQMIIEYKLPTIVMLTKVFE
.|.  ||.|| | .  .|||.|.. |
dtfddFWrmiWeqnvaiivmitnlve
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 1891-2008 3.8e-21 69.8 In-house 3-123 (515) alignment 
Range on Protein: 1891-2008
Range on HMM: 3-123/515.0
KVNEFPSFVSRSKRS--IEYEFEEIE--RISPiKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGH
 . .||.||.....   .  || ..    | | .. .    |   ||.... |.| . | |   . . .| |.||||| ...  .||||.|||.| ..  
plaqfPafvnknrhttlfseefhdlpgpniyp.qtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvdd

FWQMIIEYKLPTIVMLTKVFEG
||.......  ||.|.||  ||
fWrlvlqenvttiamvtklkeg
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 1892-2009 4e-28 93.4 In-house 6-127 (305) alignment 
Range on Protein: 1892-2009
Range on HMM: 6-127/305.0
VNEFPSFV----SRSKRSIEYEFEEIERISPIKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHF
.... ...    . |....| ..... . .        ..|.| ||.... ..||. . |...|...|| ||||||.|||.||..||..|||||||.  |
lddlaayikearvysdkgleaqykslyeeeesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadf

WQMIIEYKLPTIVMLTKVFEGN
|..|.|.|  |||||||. ||.
Wrliveekvstivmltklvegg
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 1892-2007 4.6e-28 93.2 In-house 4-125 (318) alignment 
Range on Protein: 1892-2007
Range on HMM: 4-125/318.0
VNEFPSFVSRSKR----SIEYEFEEIER--ISPIKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIG
|... | | | ..     .. |.|...|   .. .  |. . |.| ||. .. ..|.  | |.. |.||.| ||||.|||||.||.||||.|.|| .|| 
vedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetie

HFWQMIIEYKLPTIVMLTKVFE
 ||.|. | .  .|||||.. |
DfWrmvWeqnsavivmltqeee
subfamily_PTPN9_pd Subfamily PTPN9 1893-2008 2.5e-27 90.7 In-house 4-122 (297) alignment 
Range on Protein: 1893-2008
Range on HMM: 4-122/297.0
NEFPSFVS-RSKRSIEYEFEEIERISPIKAT--SIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQ
.|. ..|  . || .  |..|| . ..      |    |   ||..||  .|.  | |.. ...| | ||||...|||..|.|.||||||||.|.  ||.
eelvayvkekgkrGlskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWr

MIIEYKLPTIVMLTKVFEG
|. | .  .||| |.| | 
mvWeqevlvivmttrvver
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 1898-2007 3.6e-28 93.6 In-house 17-127 (319) alignment 
Range on Protein: 1898-2007
Range on HMM: 17-127/319.0
FVSRSKRSIEYEFEEIERISPIKA-TSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKL
. | .....| ||....  .. .  ..   .|   ||.... ..|   | ||. .  |.| |||||.|||||.....||||.||.|||  ||.|. |.. 
lastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeees

PTIVMLTKVFE
 ..|||||. |
sivvmltklve
subfamily_PTPRK_pd Subfamily PTPRK 1898-2007 6.8e-24 79.3 In-house 12-122 (314) alignment 
Range on Protein: 1898-2007
Range on HMM: 12-122/314.0
FVSRSKRSIEYEF-EEIERISPIKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKL
 ..  ||.  | | || | .     ..   .| . ||..|. ..|   | | | . . .| ||||..||.|.| .|.|.|||||..|.  ||... ... 
siallkraegygfkeeyeslfegwdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydenc

PTIVMLTKVFE
 .|||||.. |
asivmltelve
subfamily_Sponge-PTP3_pd Subfamily Sponge-PTP3 1900-1978 2.2e-12 41.0 In-house 19-95 (95) alignment 
Range on Protein: 1900-1978
Range on HMM: 19-95/95.0
SRSKRSIEYEFEEIERISPIKATsIGSK--NAAFNRFEDVCPFDDNIVPLSTsekEEDSIYINASYIDGYQRKNAYIATQG
| | . .. ||  |   |    | .||   |   ||| .. |.|   | |.|     || |||| ..||| |||.|||.||
snsdqefdnefksismtsgapyt.vgsseanipknrflnifpydatrvvltt...krdsdyinacfvdgyarkncyiaaqg
0051299 (Phosphotyrosine protein) phosphatases II 1901-2009 9.4e-33 109.3 In-house 20-130 (288) alignment 
Range on Protein: 1901-2009
Range on HMM: 20-130/288.0
RSKRSIEYEFEEIERISPIKA--TSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPT
...  .. ||||. .. |     ...  .|   ||. |. |.|.. | ||. ...|.| ||||||||||..|...|||||||.||...||.|. |.. ..
ngltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrv

IVMLTKVFEGN
||||||..| .
Ivmltklvelg
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 1901-2009 1.4e-29 98.0 In-house 18-128 (288) alignment 
Range on Protein: 1901-2009
Range on HMM: 18-128/288.0
RSKRSIEYEFEEIERISPIKATSIGS--KNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPT
|..  .. |.. .  .   |....|.  .||  ||.... |.| . | |   |.|... |||||||||...|..|||||||| .|...||... |.|  |
rnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktst

IVMLTKVFEGN
|||||.. ||.
ivmltelvegg
subfamily_PTPN6_pd Subfamily PTPN6 1901-2007 1e-20 69.0 In-house 23-134 (306) alignment 
Range on Protein: 1901-2007
Range on HMM: 23-134/306.0
RSKRSIEYEFEEIERI--SPIKATSIGS--KNAAFNRFEDVCPFDDNIVPLStSEKEEDSIYINASYIDGYQR--KNAYIATQGPLKNTIGHFWQMIIEY
 .|  .| ||||...   .     . |.  .|.  ||.. . |||.. | |. ...  .| ||||.||.. ..  ...|||||| |..|.  ||.|. . 
lekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqe

KLPTIVMLTKVFE
.   |||.||  |
nsrvivmttkevE
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 1902-2010 1.8e-44 146.8 In-house 4-111 (267) alignment 
Range on Protein: 1902-2010
Range on HMM: 4-111/267.0
SKRSIEYEFEEIERISPIKAT---SIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEedsiYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPT
....||.|||.|..||....|   ||..||...||..|..|.||..|.|.|.|.|    ||||||..||..|||.|.||.||||||..|...|...|.|.
eeceiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpv

IVMLTKVFEGNI
||.|||||..||
ivlltkvftdni
0039614 (Phosphotyrosine protein) phosphatases II 1902-2009 8.9e-31 102.9 In-house 30-139 (297) alignment 
Range on Protein: 1902-2009
Range on HMM: 30-139/297.0
SKRSIEYEFEEIERISPIKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKE-EDSIYINASYIDGYQR-KNAYIATQGPLKNTIGHFWQMIIEYKLPTI
||  ...||||. .. | . ..   .|  .||. |. |.|.. | |.. ..  .|| ||||||.||| . ....|||||||..|...||.|. |.. ..|
sktllllefeellslkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvi

VMLTKVFEGN
||||| .| .
vmLtklvelg
0050432 (Phosphotyrosine protein) phosphatases II 1903-2009 3e-31 104.3 In-house 41-146 (308) alignment 
Range on Protein: 1903-2009
Range on HMM: 41-146/308.0
KRSIEYEFEEIERISPIKA--TSIGSKNAAFNRFEDVCPFDDNIVPLstsekEEDSIYINASYIDGY--QRKNAYIATQGPLKNTIGHFWQMIIEYKLPT
.  .| ||||. .. |.    ..   .|  .||. |. |.| . | |     .|.| ||||||.|||   .....|||||||.||...||.|. |.. ..
lglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrv

IVMLTKVFEGN
|||||| .| .
IvmLtklveng
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 1903-2009 1.7e-22 74.8 In-house 4-111 (274) alignment 
Range on Protein: 1903-2009
Range on HMM: 4-111/274.0
KRSIEYEFEEIERISPIKATSIGSkNAAFNRFEDVCPFDDNIVPL-STSEKEEDSIYINASYIDGYQRK-NAYIATQGPLKNTIGHFWQMIIEYKLPTIV
 ...| || |.    . . ...   ..  ||.... | .   | | | | ..||| |||| || ||... .||.|||||| ||.  ||.|| . . . ||
fkdlekeflelPlnfdqeeldvfg.sqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqviv

MLTKVFEGN
||||. | |
mltklkean
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 1903-2008 2.8e-22 73.8 In-house 14-122 (301) alignment 
Range on Protein: 1903-2008
Range on HMM: 14-122/301.0
KRSIEYEFEEIERISPIKA-TSIGSKNAAFNRFEDVCPFDDNIVPLSTSEK--EEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTI
. ..| ...|... .. ..  .. ..|.|.|||... ..||| . |.. ..       ||||||||||..|...||.|||.|.|.  ||..|...|  .|
snkfeeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsi

VMLTKVFEG
||.|.  ||
vmvtnlkeg
0040438 (Phosphotyrosine protein) phosphatases II 1904-2009 4.8e-31 103.6 In-house 18-124 (317) alignment 
Range on Protein: 1904-2009
Range on HMM: 18-124/317.0
RSIEYEFEEIERISPI-KATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVML
. .. |||.. ....    ...  .|  .||. |. |.|.. | ||  .. .|| ||||||.||...|...|||||||.||...||.|. |... .||||
talleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmL

TKVFEGN
|. .| .
teleelg
0047943 (Phosphotyrosine protein) phosphatases II 1904-2008 3.4e-30 100.9 In-house 12-114 (273) alignment 
Range on Protein: 1904-2008
Range on HMM: 12-114/273.0
RSIEYEFEEIERISPIK--ATSIGSKNAAFNRFEDVCPFDDNIVPLstseKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVM
. .. |||.. .. |.    ...  .|  .||. |. |.|.. | |    ....| ||||||.|||..|...|||||||.||...||.|. |.. ..|||
tllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVm

LTKVFEG
||...| 
Ltelvel
0043336 (Phosphotyrosine protein) phosphatases II 1904-2009 5.2e-30 100.3 In-house 20-126 (278) alignment 
Range on Protein: 1904-2009
Range on HMM: 20-126/278.0
RSIEYEFEEIERISPiK--ATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVM
. .. ||||. .. .     ...  .|  .||. |. |.| . | ||  ....|| ||||||.|||......|||||||..|...||.|. |.. .||||
tllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivm

LTKVFEGN
||. .| .
Ltelvelg
0045450 (Phosphotyrosine protein) phosphatases II 1904-2009 1e-29 99.7 In-house 27-145 (307) alignment 
Range on Protein: 1904-2009
Range on HMM: 27-145/307.0
RSIEYEFEEIERISP----IKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKE-EDSIYINASYI--------DGYQRKNAYIATQGPLKNTIGHFWQM
  .. |||.. .. .       ..   .|  .||. |. |.|.. | ||. ... ||| ||||||.        ||| .|...|||||||..|. .||.|
tgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrm

IIEYKLPTIVMLTKVFEGN
. |..  .|||||. .| .
lweqgvtvivmltelvelg
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 1904-2007 1.8e-11 38.2 In-house 25-130 (290) alignment 
Range on Protein: 1904-2007
Range on HMM: 25-130/290.0
RSIEYEFEEIERISPI-----KATSIGSKNA--AFNRFEDVCPFDDNIVPLSTSekeEDSIYINASYIDGYqrKNAYIATQGPLKNTIGHFWQMIIEYKL
   |.  | .|.. |         .|  ||.    ||. ||   |   | |.      |  |. | |..|   |  .| |||.||.|.  .|.|... | 
nvdelakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilkdG...ydGdyvhanyvkGl..kamfiltqGalkdtvidiwrmvlqekv

PTIVMLTKVFE
 .|||| ...|
aaivmlcelie
subfamily_Ptp69D_pd Subfamily Ptp69D 1905-2009 3.1e-26 87.2 In-house 23-129 (307) alignment 
Range on Protein: 1905-2009
Range on HMM: 23-129/307.0
SIEYEFEEIERISPIKATSIGS--KNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVML
 .. |.|..|.    | |...    ||  ||.||. .||.. | |.. . .||| |||||.| ||. |. .|| |.|. .||| ||.|| | .. .||||
glakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivml

TKVFEGN
... | |
snltekn
subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 1905-2007 5.6e-10 33.7 In-house 20-118 (288) alignment 
Range on Protein: 1905-2007
Range on HMM: 20-118/288.0
SIEYEFEEIERISPIKATSIGSKNAAFNRFEDVCPFDDNIVPLStsekEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTK
... |...    ..|.. .   .|.. .|.|..   |   | ||    ..   ||.|  .   . |.  | .| ||. ||. .|.|..|  .  ||||..
glkkeyrdspneasidiidsfianptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlce

VFE
. |
lle
0046845 (Phosphotyrosine protein) phosphatases II 1906-2009 8.1e-31 102.9 In-house 2-115 (284) alignment 
Range on Protein: 1906-2009
Range on HMM: 2-115/284.0
IEYEFEEIERISPIK----ATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKE-EDSIYINASYIDGY-----QRKNAYIATQGPLKNTIGHFWQMIIEYK
.| ||||. .. .       ...  .|   ||. |. |.|.. | |.. ... ||| ||||||.|||      .|...|||||||.||...||.|. |..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn

LPTIVMLTKVFEGN
 ..|||||. .| .
vrvIVmltelveng
0036941 (Phosphotyrosine protein) phosphatases II 1906-2009 2.7e-30 101.1 In-house 15-116 (297) alignment 
Range on Protein: 1906-2009
Range on HMM: 15-116/297.0
IEYEFEEIERISPIKA--TSIGSKNAAFNRFEDVCPFDDNIVPLstseKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLT
.. ||||. .. ..    ...  .|   ||. |. |.|.. | |    ..|.| ||||||.|||..|...|||||||.||...||.|. |.. ..|||||
llkefeellpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmlt

KVFEGN
...| .
elvelg
DSPc_SM00195 1906-2008 4.8e-30 100.1 In-house 2-106 (263) alignment 
Range on Protein: 1906-2008
Range on HMM: 2-106/263.0
IEYEFEEIERISP--IKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLT
.. |||..|.  .   . ... .|| . ||.... |.|.. | |...||.|.| ||||.||.|...|..||||||||..|. .||.|..| | ..|||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt

KVFEG
. .| 
eeeen
PTPc_SM00194 1906-2008 4.8e-30 100.1 In-house 2-106 (263) alignment 
Range on Protein: 1906-2008
Range on HMM: 2-106/263.0
IEYEFEEIERISP--IKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLT
.. |||..|.  .   . ... .|| . ||.... |.|.. | |...||.|.| ||||.||.|...|..||||||||..|. .||.|..| | ..|||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt

KVFEG
. .| 
eeeen
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 1906-2004 8.8e-28 92.5 In-house 36-137 (319) alignment 
Range on Protein: 1906-2004
Range on HMM: 36-137/319.0
IEYEFEEIERISPIKATSIG---SKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVML
.| ||  . ....  |.       .|   ||. .. .|| |.| |   . || | |||||...|||||. |||.||||.||.  ||.|| ||.  |||.|
levefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivll

TK
||
tk
0045098 (Phosphotyrosine protein) phosphatases II 1906-2009 1.2e-26 89.2 In-house 11-102 (278) alignment 
Range on Protein: 1906-2009
Range on HMM: 11-102/278.0
IEYEFEEIERISPIKATSIGSKNAAFNRFEDVCPFDDNIVPlstsekeeDsiYINASYIDGYqrKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKV
.|.||  .  |     ...  .|...||. |. |.| . |         |  ||||||||||  ....|||||||..|. .||.|. |.. ..|||||..
lefefllllgipseitpalylgnldknRykdilpydhsrVk........d..YINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltel

FEGN
.|..
velg
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 1906-2009 1.7e-23 78.1 In-house 17-122 (281) alignment 
Range on Protein: 1906-2009
Range on HMM: 17-122/281.0
IEYEFEEIERISP--IKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLT
   |.|... |        |   .|   ||. ... .|   | .. .|..... ||||....||. ...|||||||. ... .||||..|.|  .|||.|
fieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvt

KVFEGN
.  |..
reieag
subfamily_ptpA1_pd Subfamily ptpA1 1906-2005 1.3e-15 52.0 In-house 23-123 (418) alignment 
Range on Protein: 1906-2005
Range on HMM: 23-123/418.0
IEYEFEEIERISPIKATSIGSK--NAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNaYIATQGPLKNTIGHFWQMIIEYKLPTIVMLT
|. ||  .|       || | |  |.. ||. .. | .   | |   . .| | |||| ||||   |. .|.||||| |||  ||.|. | .   ||||.
ikeefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkq.fictqgplpntiadfwrmvwenrcriivmls

KV
. 
re
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 1906-2007 6e-12 40.2 In-house 18-118 (307) alignment 
Range on Protein: 1906-2007
Range on HMM: 18-118/307.0
IEYEFEEIERISPI-KATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDsiYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTK
.  ||... . .|   ..   | |.  ||..||   | . . . ..    |  || | |.    . . .|..||||.||. .|| |.|. |. ...|| |
lvdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdglasd..yihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlck

VFE
| |
vie
subfamily_CG42327_pd Subfamily CG42327 1906-2008 2.6e-11 37.8 In-house 7-109 (319) alignment 
Range on Protein: 1906-2008
Range on HMM: 7-109/319.0
IEYEFEEIERISpIKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQR-KNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTK
.  ||... ..   .|  .       .|. .| |. .  | |    ... . |..|||. ||.  .| |||.| .|...   ||... | .  .|| ||.
vaeefrdlPqli.aradevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltd

VFEG
..| 
lsel
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 1907-2007 1.3e-19 65.0 In-house 23-127 (439) alignment 
Range on Protein: 1907-2007
Range on HMM: 23-127/439.0
EYEFEEIERISPI---KATSIG-SKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVML
. .||.|. .||    .|. .  . . . ||..|| .||   | |        | |||| ||.||  .. ||||||| |.|  .||...|| |  |||||
keifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivml

TKVFE
|...|
tnlve
subfamily_PTPN13_pd Subfamily PTPN13 1907-2008 6.1e-19 63.4 In-house 14-114 (273) alignment 
Range on Protein: 1907-2008
Range on HMM: 14-114/273.0
EYEFEEIERISPIKATSIGSK--NAAFNRFEDVCPFDDNIVPLSTSEKeedsiYINASYIDGYQRKN--AYIATQGPLKNTIGHFWQMIIEYKLPTIVML
. ||.|.. . |.. ...| |  | . ||. .| |.|.  |.|. .       |||||.|     |.   |||.|||| .|.  ||||. | |   |.|.
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamv

TKVFEG
|.  |.
tlekek
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 1908-2008 8.7e-26 85.8 In-house 31-136 (298) alignment 
Range on Protein: 1908-2008
Range on HMM: 31-136/298.0
YEFEEIERISP-I--KATSIG--SKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVML
 ||......|  |  . ....  ..|   ||. |. ..|   | |.. ...|.| |||||....|...||.||||.||..|.  ||.|..|..  |||||
lefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVml

TKVFEG
|.. | 
tnleel
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 1908-2008 2.9e-19 64.0 In-house 10-112 (283) alignment 
Range on Protein: 1908-2008
Range on HMM: 10-112/283.0
YEFEEIERIS-PIKATS--IGSKNAAFNRFEDVCPFDDNIVPLSTSEKeedsIYINASYID---GYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVM
  .| ..|.| | . .     ..|  .||.... | | ..| | .  .     ||||..|     |.... ||..|.||..|.  ||.|. . |  .|||
lfrevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivm

LTKVFEG
|||. |.
ltklqed
subfamily_PTPN14_pd Subfamily PTPN14 1908-2007 3.1e-19 64.1 In-house 27-129 (300) alignment 
Range on Protein: 1908-2007
Range on HMM: 27-129/300.0
YEFEEIE--RISPIKATSIGSKNAAFNRFEDVCPFDDNIVPLSTSeKEEDSIYINASYIDGY--QRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLT
 |.|.|   |   .  |.   .||  |||.|| |..|| | ||.. ||... ||||| |      ..  ||..||||..|.  ||||. | ..  |||||
teyeripkkredallstaklpenaeknrfkdvlPyednrvelspt.kenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlt

KVFE
.  |
eeee
subfamily_PTPN3_pd Subfamily PTPN3 1909-2007 1.9e-19 64.7 In-house 20-120 (280) alignment 
Range on Protein: 1909-2007
Range on HMM: 20-120/280.0
EFEEIERISPIKATSIG--SKNAAFNRFEDVCPFDDNIVPLSTSEKeeDsiYINASYI----DGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVML
.||.. |  |  |.|.   ..|.. ||. |..|.|.  | |. ||.  |  ||||.|.    .. .  | ||||||||..|  .||||. | |  .||||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklkeset..d..yinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivml

TKVFE
| . |
ttlve
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 1910-2004 3.8e-19 64.0 In-house 29-124 (325) alignment 
Range on Protein: 1910-2004
Range on HMM: 29-124/325.0
FEEIERISPIKAT-SIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTK
|. .    .|  . .   .| | |||..| ..| . | | | ... .| ||||||.  ...|. ..|.| || .||. .|....... . .|.| .
fgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlne
subfamily_Cele-PTP-16_pd Subfamily Cele-PTP-16 1910-2002 9.2e-11 35.9 In-house 28-114 (303) alignment 
Range on Protein: 1910-2002
Range on HMM: 28-114/303.0
FEEIER-ISPIKATSIGSKNAAFNRFEDVCPFDDNIVPLStsekeeDSIYINASYIDGYQRKNAyIATQGPLKNTIGHFWQMIIEYKLPTIVML
||..   . |  .     ||   ||| ||  .|   | ||      || || |||..   .|.| | || ||  |   ||||||| |.  ...|
fekvvsylppsvsknqfvknmdknrfvdvicldhskvkls......dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlll
subfamily_eak_pd Subfamily eak 1911-2007 3.7e-11 37.0 In-house 33-129 (332) alignment 
Range on Protein: 1911-2007
Range on HMM: 33-129/332.0
EEIERISPIKATSIGSKNAAFNR-FEDVCPFDDNIVPLSTSEKEEDSiYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
.....  .... | ...  | ||   .. |.| . | |..| ....  ||||| ..  .  . || |  . .. .  ||||..| | |.||.| .  |
adlddyqrllsisetarleavnrnvvkivpydrylvrltssqlnrlG.yinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledve
subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 1913-2002 1.9e-07 24.9 In-house 21-116 (347) alignment 
Range on Protein: 1913-2002
Range on HMM: 21-116/347.0
IERISPIKATSIG-SKNAAFNRFEDVCPFDDNIVPLStSEK------EEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVML
.   || | ||    |. . ||  ||   |.  | ||  ||      ..   |||||.|   . .. || || || .|.  ||.|.   |.  .| .
lanyspskftsvewekslsknrskdvklidatrvvls.peksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 1915-2008 1.9e-22 74.6 In-house 37-129 (315) alignment 
Range on Protein: 1915-2008
Range on HMM: 37-129/315.0
RISPIKaTSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
.. |.. ..  ..|   ||. .. ..|   | |   |....| |.||..||||..|. |||.|||. .... ||... |... .|||||.. ||
qlhpld.vakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlveg
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 1918-2010 7.3e-14 46.2 In-house 35-143 (350) alignment 
Range on Protein: 1918-2010
Range on HMM: 35-143/350.0
PIKA--TSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEED--------SIYINASYIDGY----QRKNA--YIATQGPLKNTIGHFWQMIIEYKLPTIVM
|.     | | .  | ||.... |.. . | |  | |  |        . ||||.|.       . .    |||||.||..|.  |...|.. | . |..
psnDvilseGvelfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvils

LTKVFEGNI
||. .| |.
ltsdvelnl
subfamily_PTPRN_pd Subfamily PTPRN 1920-2007 6.8e-20 66.0 In-house 48-136 (297) alignment 
Range on Protein: 1920-2007
Range on HMM: 48-136/297.0
KATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYI-DGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
|...   ||.  || ..| |.|...| |... ..|.| ||||| | |   |. ||||||||| .|. .||||. |     ||.||.. |
kevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrlee
subfamily_PTPN23_pd Subfamily PTPN23 1920-2006 2.8e-17 57.5 In-house 35-118 (288) alignment 
Range on Protein: 1920-2006
Range on HMM: 35-118/288.0
KATSIGSKNAAFNRFEDVCPFDDNIVPLStseKEE-DsiYINASYIDGYQRK-NAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVF
....|  ...  ||..|. |.| | | |    ... |  |||||.. .       .||||.||..|.. ||.|. | | ..||||..  
rsiaiaklyseknrsrdilPyDhnRvklr...gskDD..YinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllske
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 1921-2008 4.1e-24 80.0 In-house 39-128 (290) alignment 
Range on Protein: 1921-2008
Range on HMM: 39-128/290.0
ATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEED--SIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
 . ..|.|   |||... . ||| ..|    ...|    ||||.||.||. |..|||||||..||. .||..| . | . |||||.. | 
tvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniiee
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 1921-2007 6.9e-23 76.0 In-house 40-122 (287) alignment 
Range on Protein: 1921-2007
Range on HMM: 40-122/287.0
ATSIGSKNAAFNRFEDVCPFDDNIVPLStsekEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
  .| |.|   ||.... . |.. |.|     .|.  ||||..||||. |.|.|....|. ||.  ||..| . . ..||||..  |
thniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqeke
subfamily_CG7180_pd Subfamily CG7180 1921-2007 2.5e-21 70.6 In-house 35-121 (296) alignment 
Range on Protein: 1921-2007
Range on HMM: 35-121/296.0
ATSIGSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
|. ....|   ||  .| |.| | | |.. . ||.| ||||.|.|.. .|..|| |..| |.|.. ||... . .  ..|.|||.|.
agglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfd
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 1923-2008 1.7e-12 41.9 In-house 26-113 (297) alignment 
Range on Protein: 1923-2008
Range on HMM: 26-113/297.0
SIGSKNAA--FNRFEDVCPFDDNIVPLSTSEKEEDsiYINASYIDGY--QRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
|   .|..   ||. |.  .||. | |  .  |.|  |||| |.     . .  || .||||..|.  ||... |  . .|||..|. |.
ssakrnsslrknryrdilatddtrvkllrviterd..yinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqed
subfamily_PTPN1_pd Subfamily PTPN1 1924-2008 5.5e-20 66.3 In-house 28-108 (290) alignment 
Range on Protein: 1924-2008
Range on HMM: 28-108/290.0
IGSKNAAFNRFEDVCPFDDNIVPLSTSEKeedsIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
   .| . ||. || |.|   . |  ...     ||||| ..  . |  || ||||| ||..|||||. | |  ..||| || | 
klpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvek
subfamily_Sponge-PTP4_pd Subfamily Sponge-PTP4 1924-2007 1.3e-11 38.6 In-house 92-173 (244) alignment 
Range on Protein: 1924-2007
Range on HMM: 92-173/244.0
IGSKNAAFNRFEDVCPFDDNIVPLSTSEKeeDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
.  .|.  ||     ||| | |||| .       |||||..    |   || || || .|   ||.|..| ..  .|.|  | |
fnpnnswknregaglpfdfnrvplskgsm..gntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee
subfamily_PTPRA_pd Subfamily PTPRA 1925-2007 3.6e-26 86.8 In-house 55-137 (330) alignment 
Range on Protein: 1925-2007
Range on HMM: 55-137/330.0
GSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
  .|   ||. .. |.| . | ||. | .|.| |||||.||||..|. .||.|||...|.  ||.|| |.|  ||||||.. |
keenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelke
subfamily_PTPN12_pd Subfamily PTPN12 1925-2007 2.3e-24 80.8 In-house 37-119 (290) alignment 
Range on Protein: 1925-2007
Range on HMM: 37-119/290.0
GSKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
 ..| . ||. |. |.| . | ||. |.||.| ||||..| | . | .|||.|||| .|.  ||.||.|...  .||. ...|
keenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCreve
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 1925-2007 2.2e-21 70.9 In-house 35-116 (287) alignment 
Range on Protein: 1925-2007
Range on HMM: 35-116/287.0
GSKNAAFNRFEDVCPFDDNIVPLStSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
   ..  ||. || |.||. | ||  | |  | |||| |. .|....|.||.|||.  |.. ||....| .  .....|.  |
elaavkknryadvlPiddtrvlls.aegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreve
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 1925-2007 6.5e-10 33.2 In-house 45-124 (305) alignment 
Range on Protein: 1925-2007
Range on HMM: 45-124/305.0
GSKNAAFNRFEDVCPFDDNIVPLSTSEKEEdsiYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
 ...|  ||. ||  .|.| | | ..   |   || | |.      . .| || ||..|   || | .. |. .| || .. |
eaqeagknrykdvgcldnnrvklegpwphe...yihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnlle
0040439 (Phosphotyrosine protein) phosphatases II 1926-2008 2.4e-27 91.6 In-house 9-91 (249) alignment 
Range on Protein: 1926-2008
Range on HMM: 9-91/249.0
SKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
 .|   ||. |. |.| . | ||  .. ..| ||||||||||..|...|||||||..|...||.|. |..  .|||||. .| 
penkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvel
0042113 (Phosphotyrosine protein) phosphatases II 1926-2008 2.5e-26 88.0 In-house 7-89 (245) alignment 
Range on Protein: 1926-2008
Range on HMM: 7-89/245.0
SKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
 .|  .||..|. |.|.. | ||  . ..|| ||||||.|||.... .|||||||..|...||.|. |... ||||||. .| 
penkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeel
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 1926-2009 9.5e-22 72.2 In-house 18-102 (270) alignment 
Range on Protein: 1926-2009
Range on HMM: 18-102/270.0
SKNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQ-RKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEGN
 .....||..|. |     | |.. |... . |||| |. |.. .|..|||..|||..|. .||.||.| | ..|||.|.. | .
argkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkg
0037934 (Phosphotyrosine protein) phosphatases II 1926-2008 6.4e-21 70.5 In-house 8-85 (243) alignment 
Range on Protein: 1926-2008
Range on HMM: 8-85/243.0
SKNAAFNRFEDVCPFDDNIVPLstsekeEDSIYINASYIDGYQRknaYIATQGPLKNTIGH----FWQMIIEYKLPTIVMLTKVFEG
  |   ||. |. |.|.. | |      |.| ||||..|... |   .|||||||..|. .    ||.|. |..  .|||||. .| 
penlsknrysdilpydhsrvkl......egsdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvEl
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 1926-2009 5.2e-11 37.0 In-house 33-113 (285) alignment 
Range on Protein: 1926-2009
Range on HMM: 33-113/285.0
SKNAAFNRFEDVCPFDDNIVPLstseKEEDSIYINASYIDGY-QRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEGN
  |  .||. ||   ..  | |    |. |  || ||..    . ...||.||||| .|.  ||.|| . |.  ..||  .||| 
eanpdlnryadvrcieetrvvl....knhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfegg
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 1927-2004 1.4e-27 91.9 In-house 24-101 (284) alignment 
Range on Protein: 1927-2004
Range on HMM: 24-101/284.0
KNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTK
.|   ||. .. .|| |.| |     || | |||||.| |||||. ||||||||.||.  ||.|| ||.  |||.|||
qnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivlltk
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 1927-2007 1.1e-22 75.5 In-house 8-88 (250) alignment 
Range on Protein: 1927-2007
Range on HMM: 8-88/250.0
KNAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
.|   ||. |. ..|   | | ... ...| |||||...||. ..|.|||||||..|| .||.|..|.|  ||||||.. |
qnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLke
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 1927-2009 1.4e-13 45.6 In-house 2-83 (237) alignment 
Range on Protein: 1927-2009
Range on HMM: 2-83/237.0
KNAAFNRFEDVCPFDDNIVPLSTSEKEedSIYINASYIDGYQR-KNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEGN
.| . ||. ..  .| . | |  .  .  | ||||.|..|..   . |||.||||...   ||||. . |   ||||| . |||
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegn
subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 1927-2007 1.3e-11 38.6 In-house 51-130 (310) alignment 
Range on Protein: 1927-2007
Range on HMM: 51-130/310.0
KNAAFNRFEDVCPFDDNIVPLSTsEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
|.   ||. ||   |.  | |   .|     || | |.     ....| .||||. ||  ||.||.. .  .|..| || |
kymhknrysdvvcldtsrvklki.dksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvge
0041856 (Phosphotyrosine protein) phosphatases II 1928-2005 1.1e-16 56.3 In-house 1-68 (182) alignment 
Range on Protein: 1928-2005
Range on HMM: 1-68/182.0
NAAFNRFEDVCPFDDNIvplstsekeeDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKV
|   ||..|. |.| ..          |. ||||....|... . .|||||||..|. .|..|. |..  |||.|| .
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnltee
0049772 (Phosphotyrosine protein) phosphatases II 1928-2007 5.2e-15 51.4 In-house 46-153 (314) alignment 
Range on Protein: 1928-2007
Range on HMM: 46-153/314.0
NAAFNRFEDVCPFDdNIVPLsTSEKEEDSIYINASYIDGYqrkNAYIATQGPLKNTIGHF----------WQMII--EYKLPTIVM--------------
|   ||. |..|.| | | |  ..  ..| ||||||.||.   ...|||||||..|.  |          |.|..  .... .|||              
nrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLd

-------LTKVFE
       |... .
aAlgKtpllildg
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 1928-2008 1.3e-12 42.5 In-house 8-89 (239) alignment 
Range on Protein: 1928-2008
Range on HMM: 8-89/239.0
NAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQR-KNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
| | ||. ..  .| . | |    ..  | ||||||.  |.   .||||||| .. . | ||.|. . .   ||||| . ||
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieg
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 1928-2008 1.3e-12 42.4 In-house 7-88 (239) alignment 
Range on Protein: 1928-2008
Range on HMM: 7-88/239.0
NAAFNRFEDVCPFDDNIVPLSTSEKEEDSIYINASYIDGYQR-KNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
| | ||. ..  .| . | |    ..  | ||||||.  |.   .||||||| .. . | ||.|. . .   ||||| . ||
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieg
subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 1928-2007 3.8e-11 37.2 In-house 55-132 (305) alignment 
Range on Protein: 1928-2007
Range on HMM: 55-132/305.0
NAAFNRFEDVCPFDDNIVPLSTSEkeeDSIYINASYIDGY-QRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
. . ||..||   | ..| |.       | || | |.      .. .|..|||| .|| .|| |.|. |.  |||| |  |
aitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktve
subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 1928-2009 1.9e-09 31.6 In-house 37-119 (281) alignment 
Range on Protein: 1928-2009
Range on HMM: 37-119/281.0
NAAFNRFEDVCPFDDNIVPLST-SEKEEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEGN
|   ||. ..  .|   | |     ... . || | ||     |  || |||| |.|   ||.|| . .  .|||| .. | |
nnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletn
subfamily_Cele-PTP-12_pd Subfamily Cele-PTP-12 1928-2004 8.1e-09 29.4 In-house 34-109 (332) alignment 
Range on Protein: 1928-2004
Range on HMM: 34-109/332.0
NAAFNRFEDVCPFDDNIVPLSTSEKEEDsiYINASYIDGYQRKNAYIATQGPLKNTI-GHFWQMIIEYKLPTIVMLTK
|  .||   .  || . | |.  . ..|  . |||..||| .|.||| .| |...     ||.|. | |   |...  
nmdmnriphlycfdhsrvelapqdgkdd..fynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgd
Y_phosphatase Protein-tyrosine phosphatase 1929-2008 1.5e-27 92.0 Pfam-A 2-79 (235) alignment 
Range on Protein: 1929-2008
Range on HMM: 2-79/235.0
AAFNRFEDVCPFDDNIVPLSTSEKEEDsiYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
   ||..|. |.|.. | |. ||...|  ||||.|..||..|...||||||||.||..||.|....|  .|||||.. | 
kkknRykdilpydktrvklkgsegpsd..YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek
Y_phosphatase Protein-tyrosine phosphatase 1929-2008 1.5e-27 92.0 In-house 2-79 (235) alignment 
Range on Protein: 1929-2008
Range on HMM: 2-79/235.0
AAFNRFEDVCPFDDNIVPLSTSEKEEDsiYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
   ||..|. |.|.. | |. ||...|  ||||.|..||..|...||||||||.||..||.|....|  .|||||.. | 
kkknRykdilpydktrvklkgsegpsd..YInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleek
subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 1929-2007 3.4e-07 24.3 In-house 44-118 (312) alignment 
Range on Protein: 1929-2007
Range on HMM: 44-118/312.0
AAFNRFEDVCPFDDNIVPLSTSEkeedSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
  .||. ..  .|     |.  |     .|| | ..    . . ...|||||.||. ||||. .     .|..|. . |
kdlnrypniqcwdrgrftlagde....nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfve
0044763 (Phosphotyrosine protein) phosphatases II 1939-2008 9.2e-08 27.4 In-house 1-61 (178) alignment 
Range on Protein: 1939-2008
Range on HMM: 1-61/178.0
PFDDNIVPLSTSEKEEDSIYINASYIDGYqrknAYIATQGPlkntiGHFWQMIIEYKLPTIVMLTKVFEG
|.|...| ||. | .| | |||||.|...     |.....|      ...... |... .||.||. .|.
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelel
0046846 (Phosphotyrosine protein) phosphatases II 1951-2008 1.6e-10 36.5 In-house 7-60 (176) alignment 
Range on Protein: 1951-2008
Range on HMM: 7-60/176.0
EKEEDSIYINASYIDGYqrknAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
  ..|. ||||..|.|.    ..||||||| .|. .|..|. |..  ..|.||. .| 
gldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevel
0043147 (Phosphotyrosine protein) phosphatases II 1953-2005 1.3e-13 46.5 In-house 2-54 (172) alignment 
Range on Protein: 1953-2005
Range on HMM: 2-54/172.0
EEDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKV
.|.| ||||||.|.|   . .||||||| ||. .||.|. |..  .||.||. 
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel
subfamily_Sponge-PTP-4_pd Subfamily Sponge-PTP-4 1954-2007 3.7e-06 21.3 In-house 11-64 (130) alignment 
Range on Protein: 1954-2007
Range on HMM: 11-64/130.0
EDSIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
..  |||||..   .| . |. || || .|  .||.|..|  .  .|.|  | |
qgntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsvee
subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 1956-2007 3.6e-10 34.1 In-house 75-126 (301) alignment 
Range on Protein: 1956-2007
Range on HMM: 75-126/301.0
SIYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
 . | | .|.   . . .||||||||||   || |.. |.. .||||..  |
rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkve
subfamily_egg_pd Subfamily egg 1957-2007 5.7e-10 33.4 In-house 69-119 (307) alignment 
Range on Protein: 1957-2007
Range on HMM: 69-119/307.0
IYINASYIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFE
 .| | ...|    | .| .| |||||   ||.|. . . . |||||   |
dfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrke
0036282 (Phosphotyrosine protein) phosphatases II 1958-2009 7.2e-11 37.6 In-house 4-50 (174) alignment 
Range on Protein: 1958-2009
Range on HMM: 4-50/174.0
YINASYIDGYQRKNAYIATQGPLKntighFWQMIIEYKLPTIVMLTKVFEGN
|||||..|.. . . .||.||||.     ||.|. |... |.|||.. .| .
yinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelg
0051429 (Phosphotyrosine protein) phosphatases II 1958-2008 1.2e-10 37.0 In-house 6-58 (272) alignment 
Range on Protein: 1958-2008
Range on HMM: 6-58/272.0
YINASYIDGYQR---KNAYIATQGPLKNTIGHFWQMiIEYKLPTIVMLTKVFEG
||||....|| |   ........|||..|. .||..  |... |||.|....| 
yiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeEr
0051082 (Phosphotyrosine protein) phosphatases II 1958-2007 1.6e-06 23.3 In-house 5-45 (151) alignment 
Range on Protein: 1958-2007
Range on HMM: 5-45/151.0
YINASYIDGYqrknaYIATQGPLKntigHFWQMIIEYKLPTIVMLTKVFE
|||.||..|.     .....|||     .|.... |... |||.|.. .|
yinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseee
0049260 (Phosphotyrosine protein) phosphatases II 1963-2008 1.5e-09 33.2 In-house 1-46 (152) alignment 
Range on Protein: 1963-2008
Range on HMM: 1-46/152.0
YIDGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKVFEG
.|||| .....||||||. ||. .||.|. |..  ||||||. .| 
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellel
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 1965-2005 2.1e-09 31.3 In-house 230-270 (440) alignment 
Range on Protein: 1965-2005
Range on HMM: 230-270/440.0
DGYQRKNAYIATQGPLKNTIGHFWQMIIEYKLPTIVMLTKV
.|| .|||.|||| ||  |.  ||... .|.. ||.|| ..
egyskknafiatqmpldstvldfwrlvhdyristiimlnql