Gene AquePTP-sf2-2 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily AquePTP-sf2
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP149_AA protein Get Run
AqueP149_AA_0-66 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 1-69 1.7e-53 172.9 In-house 1-69 (69) alignment 
Range on Protein: 1-69
Range on HMM: 1-69/69.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGK
|||||||||||||||||||||||||||||||||||||||||||||||||||.||.||||||.|||||||
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklGk
subfamily_PTPRD_pd Subfamily PTPRD 1-72 2e-29 97.7 In-house 217-288 (564) alignment 
Range on Protein: 1-72
Range on HMM: 217-288/564.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKIEG
.|||||.| |||||||.| . . |||.||.|||.. |. .|| |..|| .|. |.|||.|..|||. |. | 
ivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntev
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 1-72 8.1e-27 89.1 In-house 216-287 (318) alignment 
Range on Protein: 1-72
Range on HMM: 216-287/318.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKIEG
.|||||.| ||||.|||. . . ||| |.|||.|. |. .|. |..||  |. | ||.|.| |||. |. | 
ivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtev
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 1-71 5.4e-26 86.4 In-house 219-289 (319) alignment 
Range on Protein: 1-71
Range on HMM: 219-289/319.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKIE
.||||| | |||||||.. . . |.| | ..|.|. |. .|  |..|| ... | ||..|| ||.. |. |
ivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdte
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 1-68 3.4e-24 80.6 In-house 226-293 (298) alignment 
Range on Protein: 1-68
Range on HMM: 226-293/298.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLG
..|.||.|.||.||||||   . |.| |. ||.|. |...|| || .|  |..|.||..|  |||. .
vivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsf
0050432 (Phosphotyrosine protein) phosphatases II 1-68 3.7e-23 77.8 In-house 235-302 (308) alignment 
Range on Protein: 1-68
Range on HMM: 235-302/308.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLG
.||||| | ||||||||. . . ... |. ||.|. |...|..||.|| ... |.|...||.| ||| 
ivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklk
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 1-69 1.1e-22 75.6 In-house 219-287 (305) alignment 
Range on Protein: 1-69
Range on HMM: 219-287/305.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGK
..|||| | ||||.|||. . . |.| |. ||.|. .. .|. |. || . ..|.|.||||.| .. |.
llVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgd
0051299 (Phosphotyrosine protein) phosphatases II 1-65 2.4e-22 75.2 In-house 222-286 (288) alignment 
Range on Protein: 1-65
Range on HMM: 222-286/288.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
.||||| | ||||||||. . . ... |. ||... |...|..||.|| ... |.|...||.|.|
vvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
0046845 (Phosphotyrosine protein) phosphatases II 1-68 2.6e-22 75.0 In-house 207-277 (284) alignment 
Range on Protein: 1-68
Range on HMM: 207-277/284.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEK---LVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLG
.||||| | ||||||||... . ... |.    ||... |...|..||.|| ..  |.|...||.|.|||.
ivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
0040438 (Phosphotyrosine protein) phosphatases II 1-68 9.3e-22 73.1 In-house 212-279 (317) alignment 
Range on Protein: 1-68
Range on HMM: 212-279/317.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLG
..|||| | ||||||||. . . ... |. ||... |...|..||..| ... |.|..|||.| || .
vlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 1-63 9.9e-22 72.3 In-house 215-277 (288) alignment 
Range on Protein: 1-63
Range on HMM: 215-277/288.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
..|||| | ||||||||.   . ....|. .|... |. .|| |...| ... |.||...|..
iivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevlls
0036941 (Phosphotyrosine protein) phosphatases II 1-68 1.4e-21 72.5 In-house 210-280 (297) alignment 
Range on Protein: 1-68
Range on HMM: 210-280/297.0
MVVHCSSGTGRTGTFIAIMVEMARIK---SEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLG
..|||| | ||.|||||. . . ...    |. |||.. |...|..||..| ... |.|...||.| || .
vlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
subfamily_PTPRB_pd Subfamily PTPRB 1-67 1.6e-21 71.6 In-house 221-287 (293) alignment 
Range on Protein: 1-67
Range on HMM: 221-287/293.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKL
.|||||.| ||||||||.   . .|..| .||||  |. .|. | ..| .|..|.|||... . |. 
ivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 1-88 1.6e-21 71.9 In-house 227-314 (319) alignment 
Range on Protein: 1-88
Range on HMM: 227-314/319.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKIEGVAFAGPKSLEETSSER
.|||||.|.||||..|.. | . |.| || ||..| |. .|. |. .| .  .|.||. || |   .|. . .    |  ||| |.. 
ivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleelsnks
0047943 (Phosphotyrosine protein) phosphatases II 1-65 1.6e-21 72.5 In-house 208-272 (273) alignment 
Range on Protein: 1-65
Range on HMM: 208-272/273.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
.||||| | ||||||||. . . ... |. ||... |...|..||.||.... |.|...||.| |
vvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
PTPc_DSPc_SM00012 1-63 1.8e-21 71.7 In-house 42-105 (105) alignment 
Range on Protein: 1-63
Range on HMM: 42-105/105.0
MVVHCSSGTGRTGTFIAIMVEMARIKSE-KLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
.||||| | ||||||.|. . . ....| | ||||. |...|| || || .|..|.|...||.|
vvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyralle
subfamily_PTPRK_pd Subfamily PTPRK 1-69 2.7e-21 70.7 In-house 213-281 (314) alignment 
Range on Protein: 1-69
Range on HMM: 213-281/314.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGK
.|||||.|.||||||||| . .  |. |..||.|| |. .|. .. ||  |. |.||.|.. ||   |.
ivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcge
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 1-88 3e-21 71.1 In-house 191-278 (284) alignment 
Range on Protein: 1-88
Range on HMM: 191-278/284.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKIEGVAFAGPKSLEETSSER
.|||||.|.||||..|.. | . |.| || ||..| |. .|. |. .| .  .|.||. || |   .|. . .    |  ||| |.. 
ivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleelsnks
subfamily_PTPRA_pd Subfamily PTPRA 1-71 4.2e-21 70.2 In-house 231-301 (330) alignment 
Range on Protein: 1-71
Range on HMM: 231-301/330.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKIE
.|||||.|.|||||||..   ..|.|.|..||.|. |. .|. || ||  .. | ||. .| |    |  |
ivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdte
Y_phosphatase Protein-tyrosine phosphatase 1-63 5.1e-21 70.5 Pfam-A 173-235 (235) alignment 
Range on Protein: 1-63
Range on HMM: 173-235/235.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
.||||| |.||||||.|... . ....|. ||... |. .||.||.|| ....|.|...|..|
vvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
Y_phosphatase Protein-tyrosine phosphatase 1-63 5.1e-21 70.5 In-house 173-235 (235) alignment 
Range on Protein: 1-63
Range on HMM: 173-235/235.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
.||||| |.||||||.|... . ....|. ||... |. .||.||.|| ....|.|...|..|
vvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
0039614 (Phosphotyrosine protein) phosphatases II 1-67 5.2e-21 70.8 In-house 225-291 (297) alignment 
Range on Protein: 1-67
Range on HMM: 225-291/297.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKL
..|||| | ||||||||.   . ....|. ||... |...|..||..|.... |.|..|||.| || 
vlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr
DSPc_SM00195 1-65 5.3e-21 70.5 In-house 198-262 (263) alignment 
Range on Protein: 1-65
Range on HMM: 198-262/263.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
.||||| | ||||||..| . . ....|| ||||. |. .|| ||.|| ....|.||..|..|..
ivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
PTPc_SM00194 1-65 5.3e-21 70.5 In-house 198-262 (263) alignment 
Range on Protein: 1-65
Range on HMM: 198-262/263.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
.||||| | ||||||..| . . ....|| ||||. |. .|| ||.|| ....|.||..|..|..
ivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 1-66 7.6e-21 69.3 In-house 213-278 (315) alignment 
Range on Protein: 1-66
Range on HMM: 213-278/315.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
..||||.|.|||| .|.|.  .|.|| .. ||.|| |. .|. || .|  |.|| ||.||. | |.
llvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 1-71 8.2e-21 69.4 In-house 224-294 (325) alignment 
Range on Protein: 1-71
Range on HMM: 224-294/325.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKIE
..||||.| ||||.||..   .|..  |  ||||. |. .|| || ||   ..|..|..||.||.  |. .
ilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntd
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 1-66 8.8e-21 69.2 In-house 178-243 (250) alignment 
Range on Protein: 1-66
Range on HMM: 178-243/250.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
..|.||.|.||.|.||||   . |.| || ||.|. .. .|| || .|  .. |.|.. .. .||.
vivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 1-66 1e-20 68.3 In-house 212-277 (515) alignment 
Range on Protein: 1-66
Range on HMM: 212-277/515.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
...|||.| |||| .|.|.  .|..|  . ||.|| |. .|. || .|  ...| ||..|. | |.
liihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
0043336 (Phosphotyrosine protein) phosphatases II 1-64 1.3e-20 69.5 In-house 213-276 (278) alignment 
Range on Protein: 1-64
Range on HMM: 213-276/278.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
..|||| | ||||||||. . . ....|. ||... |...|..||..|.... |.|...||.| 
vlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 1-68 3.2e-20 67.2 In-house 202-269 (283) alignment 
Range on Protein: 1-68
Range on HMM: 202-269/283.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLG
.|||||.| |||..|||... .  ...| .||.|. |. ||. |.|.| . . |...|..  |    |
ivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcg
0045450 (Phosphotyrosine protein) phosphatases II 1-65 4.2e-20 68.1 In-house 237-304 (307) alignment 
Range on Protein: 1-65
Range on HMM: 237-304/307.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKL---VDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
..|||| | ||||||||. . . ....|.    ||... |...|..|| .| |.. |.|...||.| |
vlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
subfamily_PTPRG_pd Subfamily PTPRG 1-68 5.6e-20 66.1 In-house 223-290 (563) alignment 
Range on Protein: 1-68
Range on HMM: 223-290/563.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLG
.|||||.|.|||||.|..   . .|..|. |..|. .. .|  |...| .|..|.|.|||| ||.. .
ivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiask
0042113 (Phosphotyrosine protein) phosphatases II 1-65 1.1e-19 66.3 In-house 179-243 (245) alignment 
Range on Protein: 1-65
Range on HMM: 179-243/245.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
..|||| | ||||||||.   . ....|. |.... |...|..||..|.... |.|...||.| |
vlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
subfamily_Ptp69D_pd Subfamily Ptp69D 1-69 1.7e-19 65.1 In-house 222-290 (307) alignment 
Range on Protein: 1-69
Range on HMM: 222-290/307.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGK
.||||| |.||.|.|.|. . . ..| |. ||||. |. .|. |...| . . |.|.. ||..  . |.
ivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygd
0040439 (Phosphotyrosine protein) phosphatases II 1-64 2.7e-19 65.2 In-house 182-245 (249) alignment 
Range on Protein: 1-64
Range on HMM: 182-245/249.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
..|||| | ||||||||.   . ... |. ||... |...|..||..|.|.. |.|...||.| 
vlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 1-68 5.9e-19 63.1 In-house 215-282 (315) alignment 
Range on Protein: 1-68
Range on HMM: 215-282/315.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLG
.|||||.| |||||||..   . ... |...|..| .. .|. |  ||   ..| ||.||| |..  |
ivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcg
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 1-66 6e-19 63.3 In-house 220-285 (297) alignment 
Range on Protein: 1-66
Range on HMM: 220-285/297.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
..|||..| |||| ...|   .|..| || ||||. |. .|. || .|  ...| |.. |. ||| 
llvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleall
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 1-64 3e-17 57.5 In-house 195-258 (267) alignment 
Range on Protein: 1-64
Range on HMM: 195-258/267.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
.||.|| | ||.|||. |   . |.| |  .|||. .. .|. |. .|   ..|..||. ||| 
lvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaey
subfamily_PTPN9_pd Subfamily PTPN9 1-63 3.5e-17 57.4 In-house 226-288 (297) alignment 
Range on Protein: 1-63
Range on HMM: 226-288/297.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
.|||||.| |||||||.. . ..|....  ||... |...|. |  ..  .. |.| . |. |
ivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 1-66 4.9e-17 56.7 In-house 219-284 (290) alignment 
Range on Protein: 1-66
Range on HMM: 219-284/290.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
.||||| . ||...|.|... . . |.|  .|.|. .. .| ..| .|  ...| .|.. . ..|.
ivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyld
0037934 (Phosphotyrosine protein) phosphatases II 1-63 4.9e-17 57.7 In-house 181-240 (243) alignment 
Range on Protein: 1-63
Range on HMM: 181-240/243.0
MVVHCSSGTGRTGTFIAIMVEMARIkseKlVDIFNNVQYMRKCRPM-MVMNENEYMFIHDALAE
..|||| | |||||.||. . . ..   . ||... |...|..||. .| ... |.|...||.|
vlVHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyealle
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 1-70 6e-17 56.2 In-house 215-284 (439) alignment 
Range on Protein: 1-70
Range on HMM: 215-284/439.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKI
.|||||.| ||||| ||. . . ..|.|. |||   |...|| |  || .  .|.||..|. | .. |.|
vvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdi
subfamily_PTPN12_pd Subfamily PTPN12 1-65 1.3e-16 55.4 In-house 210-277 (290) alignment 
Range on Protein: 1-65
Range on HMM: 210-277/290.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKL---VDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
.|||||.| ||||| |||      .|.||.   .|.|. |. .|| |. .|  .. | ... |.|| .
lvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
subfamily_CG7180_pd Subfamily CG7180 1-64 1.9e-16 54.6 In-house 226-289 (296) alignment 
Range on Protein: 1-64
Range on HMM: 226-289/296.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
.||..| |..|.| ..|| . .  .. |. ||.|. |. .|. || .| | .||..| | | ||
vvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 1-66 2.3e-16 54.7 In-house 211-277 (281) alignment 
Range on Protein: 1-66
Range on HMM: 211-277/281.0
MVVHCSSGTGRTGTFIAIMVEMARIKSE-KLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
.|.|||.| |||||.||.   . ....| . .|. . |. .|| | .||     | |.. |. .||.
lvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
subfamily_PTPN13_pd Subfamily PTPN13 1-66 1.2e-15 52.5 In-house 205-270 (273) alignment 
Range on Protein: 1-66
Range on HMM: 205-270/273.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
.|||||.| ||.||.|.| | .  |. .| .|. . |. .|. |  .|  .. |.|.. |. |.||
ivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 1-69 1.5e-15 51.9 In-house 214-282 (287) alignment 
Range on Protein: 1-69
Range on HMM: 214-282/287.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGK
.||||| . ||...|.|. . . . | |  .|.|. .. .|  .| .|   ..|.|| |.. | |. ..
ivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfe
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 1-70 2.3e-15 51.1 In-house 229-298 (301) alignment 
Range on Protein: 1-70
Range on HMM: 229-298/301.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKI
.||||| . .|.|..... . .   |.|  ||.|. .. .|. .| .|   . |..|.|.. . |.| ..
vvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnst
subfamily_CG42327_pd Subfamily CG42327 1-62 8.4e-15 49.2 In-house 250-312 (319) alignment 
Range on Protein: 1-62
Range on HMM: 250-312/319.0
MVVHCSSGTGRTGTFIAIMVEMARIKSE-KLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALA
.||||| |.||||. ||  ... ...   . ||| . |...|. |   |.. . | ||.  | 
lvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvls
subfamily_PTPN6_pd Subfamily PTPN6 1-66 1.7e-14 48.5 In-house 230-298 (306) alignment 
Range on Protein: 1-66
Range on HMM: 230-298/306.0
MVVHCSSGTGRTGTFIAIMVEMARIKSE---KLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
.|||||.| ||||||| | . .  |...     .|| . |...|. |  .|  |. | |.. |... ..
ivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
subfamily_PTPN3_pd Subfamily PTPN3 1-64 5.1e-14 46.9 In-house 211-274 (280) alignment 
Range on Protein: 1-64
Range on HMM: 211-274/280.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
.|||||.| |||| .|.. . .| | ... | . . |. ||  | |.| ... | |. .|. ..
vvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 1-63 7.4e-14 46.4 In-house 200-262 (270) alignment 
Range on Protein: 1-63
Range on HMM: 200-262/270.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
..|||| | |||||.||.   .  ....| ||. . .. .|| |. .|   ..| |.. |..|
llvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
subfamily_PTPRN_pd Subfamily PTPRN 1-64 6.3e-12 39.8 In-house 227-291 (297) alignment 
Range on Protein: 1-64
Range on HMM: 227-291/297.0
MVVHCSSGTGRTGTFIAIMVEMARI-KSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
.|||||.|.||||..|.| . ..|. |  | .||   ....|  || .|  .... |.  |.|| 
ivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 1-63 1.1e-11 39.3 In-house 212-275 (307) alignment 
Range on Protein: 1-63
Range on HMM: 212-275/307.0
MVVHCSSGTGRTGTFIAIMVEMA-RIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
.|||||.| ||.|| .|| . .   |. .   |. . |. .|. |.  . .| .|...|  | |
vvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlle
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 1-63 1.5e-11 38.5 In-house 219-281 (290) alignment 
Range on Protein: 1-63
Range on HMM: 219-281/290.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
.|||||.| ||||||.|| | .  .   | .|. . |. .|..|   |  . .|. . ..| .
vvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilld
subfamily_PTPN14_pd Subfamily PTPN14 1-66 4.5e-11 37.3 In-house 232-297 (300) alignment 
Range on Protein: 1-66
Range on HMM: 232-297/300.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
..|||| | ||||  |   . .| .. .. .|| . .. .|. | ..| .   | |....| . ||
vlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
subfamily_PTPN23_pd Subfamily PTPN23 1-63 1.7e-10 35.2 In-house 215-278 (288) alignment 
Range on Protein: 1-63
Range on HMM: 215-278/288.0
MVVHCSSGTGRTGTFIAIMVEMARIKS-EKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
.|||||.| ||||.|  ..  .. ..  . |.|| . |. .|. |  || ..... |  .|  |
lvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavle
subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 1-61 1e-09 32.5 In-house 224-285 (305) alignment 
Range on Protein: 1-61
Range on HMM: 224-285/305.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVD-IFNNVQYMRKCRPMMVMNENEYMFIHDAL
.|||||.| ||||| .||   . .|  .| .  . . |. .|  | . . |. .|.|||  .
ivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvm
subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 1-67 1.6e-09 32.2 In-house 207-273 (288) alignment 
Range on Protein: 1-67
Range on HMM: 207-273/288.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKL
.|||.| |.|||||.| |.. .  ....  . | . .. .|. |   .  |. |...|  . | | |
ivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelll
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 1-65 4.2e-09 30.6 In-house 265-344 (350) alignment 
Range on Protein: 1-65
Range on HMM: 265-344/350.0
MVVHCSSGTGRTGTFIAIMV--------EMARIKSEK------LVD-IFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
..||||.| |||||....          |. . .|.|      . | |.  |. .|| |  || | . ..||..||    
ilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfyf
subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 1-63 8.2e-08 25.9 In-house 268-342 (349) alignment 
Range on Protein: 1-63
Range on HMM: 268-342/349.0
MVVHCSSGTGRTGTFIAI-----MVEMARIKSEKLV-------DIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
..||||.| ||||... .     ..|. . .| |.         |.  |  .|| |  || | .....|..|| .
llvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLk
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 1-63 4.9e-07 23.8 In-house 222-285 (305) alignment 
Range on Protein: 1-63
Range on HMM: 222-285/305.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNN-VQYMRKCRPMMVMNENEYMFIHDALAE
.|||||.| ||||. . .   . .. . . ..  .  .| .|. |   .  ...|.|.|. . .
ivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 1-51 6.9e-06 20.0 In-house 217-267 (301) alignment 
Range on Protein: 1-51
Range on HMM: 217-267/301.0
MVVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNE
.|||||.| ||. .||.  .   ...... ... . .. .|. |   | ..
ivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtn
subfamily_Sponge-PTP7_pd Subfamily Sponge-PTP7 2-70 2.1e-54 175.7 In-house 1-69 (69) alignment 
Range on Protein: 2-70
Range on HMM: 1-69/69.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGKI
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklGki
0045098 (Phosphotyrosine protein) phosphatases II 2-66 3.8e-19 64.6 In-house 210-273 (278) alignment 
Range on Protein: 2-66
Range on HMM: 210-273/278.0
VVHCSSGTGRTGTFIAIMVEMARIksEKLVDIFNNVQYMRKCRPM-MVMNENEYMFIHDALAEALK
.|||| | |||||..|..  . ..  |. ||... |...|..||. .|.|.. |.|....|.| |.
lVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 2-66 5.1e-18 60.1 In-house 205-269 (274) alignment 
Range on Protein: 2-66
Range on HMM: 205-269/274.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
|||||.| |||| |||| . . ... |. ||... |  .|  |  || ... | .|| ||.. ||
vvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
0051429 (Phosphotyrosine protein) phosphatases II 2-65 6.2e-17 57.6 In-house 154-225 (272) alignment 
Range on Protein: 2-65
Range on HMM: 154-225/272.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVD--------IFNNVQYMRKCRPMMVMNENEYMFIHDALAEAL
.||||.| .||||..|.   ....  |  ||        ... |...|..|| .| .|  |.|...||.|.|
lvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallell
0036282 (Phosphotyrosine protein) phosphatases II 2-59 1.1e-16 56.4 In-house 108-164 (174) alignment 
Range on Protein: 2-59
Range on HMM: 108-164/174.0
VVHCSSGTGRTGTFIAIMVEMARIKsEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHD
.|||| | |||||..|..  . ... |.|||... |. .|..||.|| ... |.|...
lVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 2-64 1.9e-16 55.0 In-house 177-239 (239) alignment 
Range on Protein: 2-64
Range on HMM: 177-239/239.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
|.|||.| ||||.|. |   . . | .| ||||| |. .|. || ||   ..|.||| |. ||
vihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavlea
0041856 (Phosphotyrosine protein) phosphatases II 2-69 4.7e-16 54.4 In-house 113-175 (182) alignment 
Range on Protein: 2-69
Range on HMM: 113-175/182.0
VVHCSSGTGRTGTFIAIMvemaRIKSEKlVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGK
.|||| | |||||..|.      .|. . |.... |...|..||.|| ..| | |...|| | |.|.|
lVHCsaGvgRtgtlvaay....lmkklg.vsleeavklvrsrRpgmvitpnqyfflqlallellllkk
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 2-62 5.1e-16 53.6 In-house 178-238 (239) alignment 
Range on Protein: 2-62
Range on HMM: 178-238/239.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALA
|.|||.| ||||.|. |   . . | .| ||||| |. .|. || ||   ..|.||| |. 
vihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavl
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 2-66 1.5e-15 51.5 In-house 173-237 (392) alignment 
Range on Protein: 2-66
Range on HMM: 173-237/392.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
..|||.| ||||  |.|   .|. |  ..||.|| |  .|. ||.||  ...| ||. |. | | 
iihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledll
0046846 (Phosphotyrosine protein) phosphatases II 2-63 4.9e-15 51.2 In-house 113-171 (176) alignment 
Range on Protein: 2-63
Range on HMM: 113-171/176.0
VVHCSSGTGRTGTFIAIMvemaRIKSEKLVDIFNNVQYMRKCRP-MMVMNENEYMFIHDALAE
.|||| | |||||..|.      ...|| ..... ....|..|| ..| ... | |..... .
lVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyefell
0048076 (Phosphotyrosine protein) phosphatases II 2-61 2.8e-14 48.5 In-house 85-139 (145) alignment 
Range on Protein: 2-61
Range on HMM: 85-139/145.0
VVHCSSGTGRTGTFIAIMvemaRIKSEKlVDIFNNVQYMRKCRPMMVMNENEYMFIHDAL
.|||| | |||||..|..     ..... |.... ....|..||..|.|.. . |.....
lVHCsaGvgRtgtlvaay....lmlllg.vsleealelvrsqrpgavpnpgqlrflyefe
0043147 (Phosphotyrosine protein) phosphatases II 2-58 2.8e-14 48.7 In-house 104-154 (172) alignment 
Range on Protein: 2-58
Range on HMM: 104-154/172.0
VVHCSSGTGRTGTFIAIMVEMarikseKLVDIFNNVQYMRKCRPMMVMNENEYMFIH
.|||| | |||||..|.   .      . ..... |...|..||..| |.. |.|..
lVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrfly
0049260 (Phosphotyrosine protein) phosphatases II 2-59 3.1e-14 48.4 In-house 93-144 (152) alignment 
Range on Protein: 2-59
Range on HMM: 93-144/152.0
VVHCSSGTGRTGTFIAIMVEMarikseKLVDIFNNVQYMRKCRPMMVMNENEYMFIHD
.|||| | |||||..|.   .      . |.... |...|..||..| |.. ..|...
lVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
0048179 (Phosphotyrosine protein) phosphatases II 2-59 3.2e-14 48.3 In-house 87-139 (144) alignment 
Range on Protein: 2-59
Range on HMM: 87-139/144.0
VVHCSSGTGRTGTFIAIMvemaRIKSEKlVDIFNNVQYMRKCRPMMVMNENEYMFIHD
.|||| | |||||..|.     ..| .. ..... ....|..||..|.|.. ..|...
lVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpgavpnpgqlrfLle
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 2-62 1e-13 46.1 In-house 176-236 (237) alignment 
Range on Protein: 2-62
Range on HMM: 176-236/237.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALA
..|||.| |||| |. |   . . | .|.|||.| |. . . || ..  ...|.|||... 
iihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqtil
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 2-69 1.1e-13 45.4 In-house 131-198 (440) alignment 
Range on Protein: 2-69
Range on HMM: 131-198/440.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALKLGK
.||||.|.||||  ||.   .   |    .|||. .. ||. || ||   ..| |.|.|. |.|  | 
lvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvheavlegllcgd
0051082 (Phosphotyrosine protein) phosphatases II 2-61 7.6e-13 43.8 In-house 96-149 (151) alignment 
Range on Protein: 2-61
Range on HMM: 96-149/151.0
VVHCSSGTGRTGTFIAIMVEMARikseklVDIFNNVQYMRKCRPMMVMNENEYMFIHDAL
.||||.| |||||..|..  . .      |...  ....|..||..|  .....|.. ||
lvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlfal
0049772 (Phosphotyrosine protein) phosphatases II 2-66 2.6e-12 42.6 In-house 216-281 (314) alignment 
Range on Protein: 2-66
Range on HMM: 216-281/314.0
VVHCSSGTGRTGTFIAIMVEMARIKseklVDIFNNVQYMRKCRP-----MMVMNENEYMFIHDALAEALK
.|||..| ||||||....  | . .    |..   ....|..||      .. . ..| ||..|| |.||
lvHCkaGkgRtgtfvvaaylmkllg....vsleealedvrlkRpinpnpgfieqleqyefilealleylk
0044763 (Phosphotyrosine protein) phosphatases II 2-64 3.9e-12 41.7 In-house 114-170 (178) alignment 
Range on Protein: 2-64
Range on HMM: 114-170/178.0
VVHCSSGTGRTGTFIAIMVEMARikseKLvDIFNNVQYMRKCRPmMVMNENEYMFIHDALAEA
.|||| | ||.||..|.   . .    .| .... ....|..|| .| |.. . ....   . 
lVHCsaGvgRsgtlvaaylmkkl....gl.sleeaielvrerRp.ivpnpgqlrqLyefelrl
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 2-64 8.4e-11 36.2 In-house 214-276 (287) alignment 
Range on Protein: 2-64
Range on HMM: 214-276/287.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
|||.. | ||.|...|..| . | ..   ||. . | ..|. |  .|     . .. .||.  
vvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvty
subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 2-64 2.1e-10 34.6 In-house 225-287 (302) alignment 
Range on Protein: 2-64
Range on HMM: 225-287/302.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
.|||| | |||||..||   .   . .|  |. . |. .|.||   | .|.  ...   .. .
lvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkg
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 2-63 7.6e-10 33.1 In-house 232-293 (297) alignment 
Range on Protein: 2-63
Range on HMM: 232-293/297.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAE
.||||.| ||.|  .  .| .|... ... |.   ....|. |...|   ... ...||  .
lvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 2-62 1.1e-08 28.9 In-house 222-282 (302) alignment 
Range on Protein: 2-62
Range on HMM: 222-282/302.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALA
|.    |.|| |.|.. .| . .....| . | . |. .|. || .| . . |.... ||.
vivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyiall
subfamily_PTPN1_pd Subfamily PTPN1 2-66 3.1e-08 27.7 In-house 205-272 (290) alignment 
Range on Protein: 2-66
Range on HMM: 205-272/290.0
VVHCSSGTGRTGTFIA---IMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEALK
|.|||.| ||.|||.    ..|.. . .  . ||| . .  .|| |  ..   .   | . |. |  |
vihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGak
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 2-64 3.7e-08 27.7 In-house 207-269 (285) alignment 
Range on Protein: 2-64
Range on HMM: 207-269/285.0
VVHCSSGTGRTGTFIAIMVEMARIKSEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALAEA
.||||.| ||| ||. |     ||  .  ..... |. ||  |   | .  ...|..  | | 
cvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmey
subfamily_CDC14_pd Subfamily CDC14 2-56 1.9e-07 25.2 In-house 267-317 (328) alignment 
Range on Protein: 2-56
Range on HMM: 267-317/328.0
VVHCSSGTGRTGTFIAIMVemarIKSEKLvDIFNNVQYMRKCRPMMVMNENE-YMF
.||| .| |||||.||  .    .|  ..    . . ..| ||| .|.   . .. 
avhCkaGLGrtGtLiacyl....mkhyrf.taaeaiawlricrPGsvigpqqkfle
subfamily_Anemone-PTP-3_pd Subfamily Anemone-PTP-3 2-58 5.5e-07 24.0 In-house 139-197 (199) alignment 
Range on Protein: 2-58
Range on HMM: 139-197/199.0
VVHCSSGTGRTGTFIAIMVEMARIKSE--KLVDIFNNVQYMRKCRPMMVMNENEYMFIH
.|||| | | || |.|. . .   .     .||.|.  . .|..|  ..   . | ||.
ivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
subfamily_Nvec-PTP-3_pd Subfamily Nvec-PTP-3 2-58 5.5e-07 24.0 In-house 138-196 (198) alignment 
Range on Protein: 2-58
Range on HMM: 138-196/198.0
VVHCSSGTGRTGTFIAIMVEMARIKSE--KLVDIFNNVQYMRKCRPMMVMNENEYMFIH
.|||| | | || |.|. . .   .     .||.|.  . .|..|  ..   . | ||.
ivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 2-60 6.7e-07 23.7 In-house 195-254 (290) alignment 
Range on Protein: 2-60
Range on HMM: 195-254/290.0
VVHCSSGTGRTGTFIAIMVEMARIK-SEKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDA
.|||  |  |  .. || . .  |  ... | . . ....|| | .......|. |.  .
ivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdag
subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 2-61 9.7e-07 22.7 In-house 204-265 (281) alignment 
Range on Protein: 2-61
Range on HMM: 204-265/281.0
VVHCSSGTGRTGTFIAIMVEMARIKSE-KLVDIFNNVQYMRK-CRPMMVMNENEYMFIHDAL
|.|||.| ||.||..|. . .  |.|   | || . | ..|   |   |   ..||.|   |
vihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvl
subfamily_PTPDC1_pd Subfamily PTPDC1 2-59 5.6e-06 20.9 In-house 118-170 (182) alignment 
Range on Protein: 2-59
Range on HMM: 118-170/182.0
VVHCSSGTGRTGTFIA-IMVEMARIKSEKlvdifnNVQYMRKCRPMMVMNENEYMFIHD
 ||| .| ||||  || ..| . |...||       .. .|. ||  .   .   ....
avhChaGlGrtGvliacylvyakrltaek......aiklvrskrpksiqtreqvelvke
0038934 (Phosphotyrosine protein) phosphatases II 2-52 8e-06 21.1 In-house 119-164 (194) alignment 
Range on Protein: 2-52
Range on HMM: 119-164/194.0
VVHCSSGTGRTGTFIAIMV-EMARIkseklvDIFNNVQYMRKCRPMMVMNEN
.|||  | |||||..|    .. ..      .    ....| .|| ...| .
aVHCkaGlgRtGtlvaaYLiyrlgm......saeeAialfrekRpgaipnqd
subfamily_egg_pd Subfamily egg 2-62 9.7e-06 19.5 In-house 205-267 (307) alignment 
Range on Protein: 2-62
Range on HMM: 205-267/307.0
VVHCSSGTGRTGTFIAIMVEMARIKS--EKLVDIFNNVQYMRKCRPMMVMNENEYMFIHDALA
||..  |  ...|..|| . .  .         . . |...|. |.. |     |.|..  ..
vvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl