Gene AquePTP-sf2-4 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily AquePTP-sf2
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP151_AA protein Get Run
AqueP151_AA_0-45 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 1-48 2.3e-36 118.0 In-house 22-69 (69) alignment
Range on Protein: 1-48
Range on HMM: 22-69/69.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
|||||||||||||||||||||||||||||||||.||||||||||||||
marikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklGk

subfamily_Sponge-PTP7_pd Subfamily Sponge-PTP7 1-49 4.2e-35 113.9 In-house 21-69 (69) alignment
Range on Protein: 1-49
Range on HMM: 21-69/69.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKI
|||||||||||||||||||||||||||||| ||.|||||||||||||||
marikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklGki

subfamily_PTPRD_pd Subfamily PTPRD 1-61 2.7e-15 51.0 In-house 238-298 (564) alignment
Range on Protein: 1-61
Range on HMM: 238-298/564.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVARPKSLE
. |||.||.|||.. |. .|| |..|| .|  |.|||.|..|||. |. |  . .  . |.
lerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlq

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 1-50 1.9e-12 41.9 In-house 240-289 (319) alignment
Range on Protein: 1-50
Range on HMM: 240-289/319.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIE
. |.| | ..|.|. |. .|  |..|| ..  | ||..||.||.. |. |
lervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdte

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 1-66 5.8e-11 37.3 In-house 248-313 (319) alignment
Range on Protein: 1-66
Range on HMM: 248-313/319.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVARPKSLEEASSE
. |.| || ||..| |. .|. |. .| . ..| ||. ||.|   .|. . .    |  ||| |..
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleelsnk

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 1-67 7.4e-11 37.1 In-house 212-278 (284) alignment
Range on Protein: 1-67
Range on HMM: 212-278/284.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVARPKSLEEASSEG
. |.| || ||..| |. .|. |. .| . ..| ||. ||.|   .|. . .    |  ||| |.. 
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleelsnks

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 1-49 3.2e-10 34.6 In-house 240-288 (305) alignment
Range on Protein: 1-49
Range on HMM: 240-288/305.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKI
. |.| |. ||.|. .. .|. |. || .  .|||.|||| | .. |. 
lerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdt

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 1-43 7.1e-10 33.4 In-house 236-278 (288) alignment
Range on Protein: 1-43
Range on HMM: 236-278/288.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
. ....|. .|... |. .|| |...| ..  |.||...|.. 
idaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsl

subfamily_PTPRA_pd Subfamily PTPRA 1-50 1.6e-09 32.1 In-house 252-301 (330) alignment
Range on Protein: 1-50
Range on HMM: 252-301/330.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIE
..|.|.|..||.|. |. .|. || ||  .  |.||. .| |    |  |
lervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdte

subfamily_PTPRB_pd Subfamily PTPRB 1-46 1.6e-09 32.3 In-house 242-287 (293) alignment
Range on Protein: 1-46
Range on HMM: 242-287/293.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKL
. .|..| .||||  |. .|. | ..| .| .|.|||..... |. 
lqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk

DSPc_SM00195 1-44 1.5e-08 29.7 In-house 219-262 (263) alignment
Range on Protein: 1-44
Range on HMM: 219-262/263.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
. ....|| ||||. |. .|| ||.|| .. .| ||..|..|..
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi

PTPc_SM00194 1-44 1.5e-08 29.7 In-house 219-262 (263) alignment
Range on Protein: 1-44
Range on HMM: 219-262/263.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
. ....|| ||||. |. .|| ||.|| .. .| ||..|..|..
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 2-55 4.2e-14 47.3 In-house 238-291 (318) alignment
Range on Protein: 2-55
Range on HMM: 238-291/318.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVA
 ||| |.|||.|. |. .|. |..||  |  |.||.|.|.|||. |. |  |  
erikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasd

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 2-47 2.2e-12 41.8 In-house 248-293 (298) alignment
Range on Protein: 2-47
Range on HMM: 248-293/298.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLG
 |.| |. ||.|. |...|| || .|  | .||||..|  |||. .
ervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsf

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 2-49 1.5e-10 35.5 In-house 235-282 (315) alignment
Range on Protein: 2-49
Range on HMM: 235-282/315.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKI
|.|| .. ||.|| |. .|. || .|  | || ||.||. | |.  . 
aqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrnt

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 2-73 1.8e-10 34.5 In-house 234-305 (515) alignment
Range on Protein: 2-73
Range on HMM: 234-305/515.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVARPKSLEEASSEGNSEGSS
|..|  . ||.|| |. .|. || .|  . .| ||..|. | |.  .     .     |..  | |. .| |
ahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlhssgdgrgrs

0050432 (Phosphotyrosine protein) phosphatases II 2-47 4.5e-10 34.8 In-house 257-302 (308) alignment
Range on Protein: 2-47
Range on HMM: 257-302/308.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLG
 ... |. ||.|. |...|..||.|| ..  |.|...||.| ||| 
eqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklk

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 2-45 6.7e-10 33.6 In-house 200-243 (250) alignment
Range on Protein: 2-45
Range on HMM: 200-243/250.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALK
 |.| || ||.|. .. .|| || .|  .  |||.. .. .||.
erlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 2-45 3e-09 31.4 In-house 242-285 (297) alignment
Range on Protein: 2-45
Range on HMM: 242-285/297.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALK
|..| || ||||. |. .|. || .|  . .| |.. |..||| 
aeakrekevdifglvkklrqerpylvqtkeqykfvyvavleall

0051299 (Phosphotyrosine protein) phosphatases II 2-44 3.9e-09 31.8 In-house 244-286 (288) alignment
Range on Protein: 2-44
Range on HMM: 244-286/288.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
 ... |. ||... |...|..||.|| ..  |.|...||.|.|
eqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl

0047943 (Phosphotyrosine protein) phosphatases II 2-44 1.2e-08 30.2 In-house 230-272 (273) alignment
Range on Protein: 2-44
Range on HMM: 230-272/273.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
 ... |. ||... |...|..||.||...  |.|...||.| |
dqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl

subfamily_Ptp69D_pd Subfamily Ptp69D 2-48 1.9e-08 28.8 In-house 244-290 (307) alignment
Range on Protein: 2-48
Range on HMM: 244-290/307.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
 ..| |. ||||. |. .|. |...| .   |||.. ||..  . |.
qqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygd

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 2-48 4.9e-08 26.8 In-house 194-240 (392) alignment
Range on Protein: 2-48
Range on HMM: 194-240/392.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
|. |  ..||.|| |  .|. ||.||  . .| ||. |..| |   .
ahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrn

PTPc_DSPc_SM00012 2-41 7.4e-08 27.9 In-house 64-104 (105) alignment
Range on Protein: 2-41
Range on HMM: 64-104/105.0
ARIKSE-KLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALV
 ....| | ||||. |...|| || || .| .|.|...|| 
qqleketkevdifqivkelrkqRpgmvqteeqylflyrall

0043336 (Phosphotyrosine protein) phosphatases II 2-43 1.2e-07 27.0 In-house 235-276 (278) alignment
Range on Protein: 2-43
Range on HMM: 235-276/278.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
 ....|. ||... |...|..||..|...  |.|...|| | 
eqlekeggvdleeavkelreqRpgavqtpsqyrflyealley

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 2-43 3.1e-06 21.4 In-house 217-258 (267) alignment
Range on Protein: 2-43
Range on HMM: 217-258/267.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
 |.| |  .|||. .. .|. |. .|    .|..||. |.| 
eraktegvsdifdflrkirsqriglvdtkeryiyihellaey

subfamily_PTPRG_pd Subfamily PTPRG 3-48 6.2e-10 32.9 In-house 246-291 (563) alignment
Range on Protein: 3-48
Range on HMM: 246-291/563.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
.|..|. |..|. .. .|  |...| .| .|.|.||||.||.. ..
qiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiaske

subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 3-50 1.1e-09 32.8 In-house 247-294 (325) alignment
Range on Protein: 3-50
Range on HMM: 247-294/325.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIE
..  |  ||||. |. .|| || ||    .|..|..|||||.  |. .
kvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntd

0046845 (Phosphotyrosine protein) phosphatases II 3-47 2.1e-09 32.7 In-house 230-277 (284) alignment
Range on Protein: 3-47
Range on HMM: 230-277/284.0
RIKSEK---LVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLG
... |.    ||... |...|..||.|| ..  |.|...||.|.|||.
qlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk

0040438 (Phosphotyrosine protein) phosphatases II 3-47 5.9e-09 31.1 In-house 235-279 (317) alignment
Range on Protein: 3-47
Range on HMM: 235-279/317.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLG
... |. ||... |...|..||..| ..  |.|..||| | || .
qlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 3-48 6.9e-09 30.1 In-house 238-283 (315) alignment
Range on Protein: 3-48
Range on HMM: 238-283/315.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
... |...|..| .. .|. |  ||    .| ||.|||.|..  | 
qaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgd

0036941 (Phosphotyrosine protein) phosphatases II 3-48 7.1e-09 30.8 In-house 233-281 (297) alignment
Range on Protein: 3-48
Range on HMM: 233-281/297.0
RIK---SEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
...    |. |||.. |...|..||..| ..  |.|...|| | || ..
qledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkl

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 3-43 1.8e-08 28.8 In-house 199-239 (239) alignment
Range on Protein: 3-43
Range on HMM: 199-239/239.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
. | .| ||||| |. .|. || ||    .||||| |..||
qakkqktvdifnyvkairedrphmvqtseqyvfihlavlea

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 3-54 2.6e-08 27.8 In-house 238-288 (439) alignment
Range on Protein: 3-54
Range on HMM: 238-288/439.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEgVAV
..|.|. |||   |...|| |  || .  .||||..|..| .. |.|  |..
qlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdia.vti

Y_phosphatase Protein-tyrosine phosphatase 3-42 3.2e-08 28.7 Pfam-A 196-235 (235) alignment
Range on Protein: 3-42
Range on HMM: 196-235/235.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVE
....|. ||... |. .||.||.|| .. .|.|...|..|
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile

Y_phosphatase Protein-tyrosine phosphatase 3-42 3.2e-08 28.7 In-house 196-235 (235) alignment
Range on Protein: 3-42
Range on HMM: 196-235/235.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVE
....|. ||... |. .||.||.|| .. .|.|...|..|
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile

0039614 (Phosphotyrosine protein) phosphatases II 3-46 3.8e-08 28.6 In-house 248-291 (297) alignment
Range on Protein: 3-46
Range on HMM: 248-291/297.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKL
....|. ||... |...|..||..|...  |.|..|||.| || 
qlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 3-42 6.3e-08 27.1 In-house 200-239 (239) alignment
Range on Protein: 3-42
Range on HMM: 200-239/239.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVE
. | .| ||||| |. .|. || ||    .||||| |..|
qakkqktvdifnyvkairedrphmvqtseqyvfihlavle

0045450 (Phosphotyrosine protein) phosphatases II 3-43 2.2e-07 26.4 In-house 260-303 (307) alignment
Range on Protein: 3-43
Range on HMM: 260-303/307.0
RIKSEKL---VDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
....|.    ||... |...|..|| .| |.  |.|...|| | 
qlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel

0042113 (Phosphotyrosine protein) phosphatases II 3-44 6e-07 24.6 In-house 202-243 (245) alignment
Range on Protein: 3-44
Range on HMM: 202-243/245.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
....|. |.... |...|..||..|...  |.|...|| | |
qlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell

0040439 (Phosphotyrosine protein) phosphatases II 3-43 1.3e-06 23.8 In-house 205-245 (249) alignment
Range on Protein: 3-43
Range on HMM: 205-245/249.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
... |. ||... |...|..||..|.|.  |.|...|| | 
qlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 3-42 8.2e-06 20.2 In-house 198-237 (237) alignment
Range on Protein: 3-42
Range on HMM: 198-237/237.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVE
. | .|.|||.| |. . . || ..  . .|||||....|
qakekkvvdiynyvysieedrpyiiqtkdqyvfihqtile

subfamily_PTPRK_pd Subfamily PTPRK 4-64 5.1e-10 33.7 In-house 237-296 (314) alignment
Range on Protein: 4-64
Range on HMM: 237-296/314.0
IKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIeGVAVARPKSLEEAS
|. |..||.|| |. .|. .. ||  |  |.||.|...||   |.   . |.. |.|   |
ieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcget.aipvsefkalyles

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 4-53 7.8e-09 29.8 In-house 226-275 (283) alignment
Range on Protein: 4-53
Range on HMM: 226-275/283.0
IKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVA
...| .||.|. |. ||. |.|.| .   | ..|.. .|    |  . .|
altesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaa

0045098 (Phosphotyrosine protein) phosphatases II 4-45 5.5e-07 24.8 In-house 233-273 (278) alignment
Range on Protein: 4-45
Range on HMM: 233-273/278.0
IksEKLVDIFNNVQYMRKCRPM-MVMNEIEYVFIHDALVEALK
.  |. ||... |...|..||. .|.|.  |.|....|.| |.
l..eggvdlleavkelrsqRpglavqnleqyrflyefllelll

subfamily_CG7180_pd Subfamily CG7180 4-43 1.9e-06 21.7 In-house 250-289 (296) alignment
Range on Protein: 4-43
Range on HMM: 250-289/296.0
IKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
.. |. ||.|. |. .|. || .| |  || .| | | ||
vekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 5-48 1e-06 22.4 In-house 155-198 (440) alignment
Range on Protein: 5-48
Range on HMM: 155-198/440.0
KSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
|    .|||. .. ||. || ||    .|.|.|.|..|.|  | 
krsdqidifsfinsmrnnrpqmvqtpeqyafvheavlegllcgd

subfamily_PTPN12_pd Subfamily PTPN12 7-44 4.5e-06 20.8 In-house 240-277 (290) alignment
Range on Protein: 7-44
Range on HMM: 240-277/290.0
EKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
.. .|.|. |. .|| |. .|  .  |.... |..| .
peeldvfdlvlelrkqraalvqtkeqyelvykavaelv