Gene AquePTP-sf2-4 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily AquePTP-sf2
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP151_AA protein Get Run
AqueP151_AA_0-45 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 1-48 2.3e-36 118.0 In-house 22-69 (69) alignment 
Range on Protein: 1-48
Range on HMM: 22-69/69.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
|||||||||||||||||||||||||||||||||.||||||||||||||
marikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklGk
subfamily_Sponge-PTP7_pd Subfamily Sponge-PTP7 1-49 4.2e-35 113.9 In-house 21-69 (69) alignment 
Range on Protein: 1-49
Range on HMM: 21-69/69.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKI
|||||||||||||||||||||||||||||| ||.|||||||||||||||
marikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklGki
subfamily_PTPRD_pd Subfamily PTPRD 1-61 2.7e-15 51.0 In-house 238-298 (564) alignment 
Range on Protein: 1-61
Range on HMM: 238-298/564.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVARPKSLE
. |||.||.|||.. |. .|| |..|| .|  |.|||.|..|||. |. |  . .  . |.
lerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlq
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 1-50 1.9e-12 41.9 In-house 240-289 (319) alignment 
Range on Protein: 1-50
Range on HMM: 240-289/319.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIE
. |.| | ..|.|. |. .|  |..|| ..  | ||..||.||.. |. |
lervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdte
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 1-66 5.8e-11 37.3 In-house 248-313 (319) alignment 
Range on Protein: 1-66
Range on HMM: 248-313/319.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVARPKSLEEASSE
. |.| || ||..| |. .|. |. .| . ..| ||. ||.|   .|. . .    |  ||| |..
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpayleelsnk
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 1-67 7.4e-11 37.1 In-house 212-278 (284) alignment 
Range on Protein: 1-67
Range on HMM: 212-278/284.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVARPKSLEEASSEG
. |.| || ||..| |. .|. |. .| . ..| ||. ||.|   .|. . .    |  ||| |.. 
ldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleelsnks
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 1-49 3.2e-10 34.6 In-house 240-288 (305) alignment 
Range on Protein: 1-49
Range on HMM: 240-288/305.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKI
. |.| |. ||.|. .. .|. |. || .  .|||.|||| | .. |. 
lerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdt
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 1-43 7.1e-10 33.4 In-house 236-278 (288) alignment 
Range on Protein: 1-43
Range on HMM: 236-278/288.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
. ....|. .|... |. .|| |...| ..  |.||...|.. 
idaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsl
subfamily_PTPRA_pd Subfamily PTPRA 1-50 1.6e-09 32.1 In-house 252-301 (330) alignment 
Range on Protein: 1-50
Range on HMM: 252-301/330.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIE
..|.|.|..||.|. |. .|. || ||  .  |.||. .| |    |  |
lervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdte
subfamily_PTPRB_pd Subfamily PTPRB 1-46 1.6e-09 32.3 In-house 242-287 (293) alignment 
Range on Protein: 1-46
Range on HMM: 242-287/293.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKL
. .|..| .||||  |. .|. | ..| .| .|.|||..... |. 
lqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
DSPc_SM00195 1-44 1.5e-08 29.7 In-house 219-262 (263) alignment 
Range on Protein: 1-44
Range on HMM: 219-262/263.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
. ....|| ||||. |. .|| ||.|| .. .| ||..|..|..
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
PTPc_SM00194 1-44 1.5e-08 29.7 In-house 219-262 (263) alignment 
Range on Protein: 1-44
Range on HMM: 219-262/263.0
MARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
. ....|| ||||. |. .|| ||.|| .. .| ||..|..|..
lskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 2-55 4.2e-14 47.3 In-house 238-291 (318) alignment 
Range on Protein: 2-55
Range on HMM: 238-291/318.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVA
 ||| |.|||.|. |. .|. |..||  |  |.||.|.|.|||. |. |  |  
erikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasd
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 2-47 2.2e-12 41.8 In-house 248-293 (298) alignment 
Range on Protein: 2-47
Range on HMM: 248-293/298.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLG
 |.| |. ||.|. |...|| || .|  | .||||..|  |||. .
ervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsf
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 2-49 1.5e-10 35.5 In-house 235-282 (315) alignment 
Range on Protein: 2-49
Range on HMM: 235-282/315.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKI
|.|| .. ||.|| |. .|. || .|  | || ||.||. | |.  . 
aqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrnt
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 2-73 1.8e-10 34.5 In-house 234-305 (515) alignment 
Range on Protein: 2-73
Range on HMM: 234-305/515.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVAVARPKSLEEASSEGNSEGSS
|..|  . ||.|| |. .|. || .|  . .| ||..|. | |.  .     .     |..  | |. .| |
ahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlhssgdgrgrs
0050432 (Phosphotyrosine protein) phosphatases II 2-47 4.5e-10 34.8 In-house 257-302 (308) alignment 
Range on Protein: 2-47
Range on HMM: 257-302/308.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLG
 ... |. ||.|. |...|..||.|| ..  |.|...||.| ||| 
eqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklk
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 2-45 6.7e-10 33.6 In-house 200-243 (250) alignment 
Range on Protein: 2-45
Range on HMM: 200-243/250.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALK
 |.| || ||.|. .. .|| || .|  .  |||.. .. .||.
erlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkald
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 2-45 3e-09 31.4 In-house 242-285 (297) alignment 
Range on Protein: 2-45
Range on HMM: 242-285/297.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALK
|..| || ||||. |. .|. || .|  . .| |.. |..||| 
aeakrekevdifglvkklrqerpylvqtkeqykfvyvavleall
0051299 (Phosphotyrosine protein) phosphatases II 2-44 3.9e-09 31.8 In-house 244-286 (288) alignment 
Range on Protein: 2-44
Range on HMM: 244-286/288.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
 ... |. ||... |...|..||.|| ..  |.|...||.|.|
eqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
0047943 (Phosphotyrosine protein) phosphatases II 2-44 1.2e-08 30.2 In-house 230-272 (273) alignment 
Range on Protein: 2-44
Range on HMM: 230-272/273.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
 ... |. ||... |...|..||.||...  |.|...||.| |
dqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
subfamily_Ptp69D_pd Subfamily Ptp69D 2-48 1.9e-08 28.8 In-house 244-290 (307) alignment 
Range on Protein: 2-48
Range on HMM: 244-290/307.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
 ..| |. ||||. |. .|. |...| .   |||.. ||..  . |.
qqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygd
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 2-48 4.9e-08 26.8 In-house 194-240 (392) alignment 
Range on Protein: 2-48
Range on HMM: 194-240/392.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
|. |  ..||.|| |  .|. ||.||  . .| ||. |..| |   .
ahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrn
PTPc_DSPc_SM00012 2-41 7.4e-08 27.9 In-house 64-104 (105) alignment 
Range on Protein: 2-41
Range on HMM: 64-104/105.0
ARIKSE-KLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALV
 ....| | ||||. |...|| || || .| .|.|...|| 
qqleketkevdifqivkelrkqRpgmvqteeqylflyrall
0043336 (Phosphotyrosine protein) phosphatases II 2-43 1.2e-07 27.0 In-house 235-276 (278) alignment 
Range on Protein: 2-43
Range on HMM: 235-276/278.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
 ....|. ||... |...|..||..|...  |.|...|| | 
eqlekeggvdleeavkelreqRpgavqtpsqyrflyealley
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 2-43 3.1e-06 21.4 In-house 217-258 (267) alignment 
Range on Protein: 2-43
Range on HMM: 217-258/267.0
ARIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
 |.| |  .|||. .. .|. |. .|    .|..||. |.| 
eraktegvsdifdflrkirsqriglvdtkeryiyihellaey
subfamily_PTPRG_pd Subfamily PTPRG 3-48 6.2e-10 32.9 In-house 246-291 (563) alignment 
Range on Protein: 3-48
Range on HMM: 246-291/563.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
.|..|. |..|. .. .|  |...| .| .|.|.||||.||.. ..
qiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiaske
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 3-50 1.1e-09 32.8 In-house 247-294 (325) alignment 
Range on Protein: 3-50
Range on HMM: 247-294/325.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIE
..  |  ||||. |. .|| || ||    .|..|..|||||.  |. .
kvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntd
0046845 (Phosphotyrosine protein) phosphatases II 3-47 2.1e-09 32.7 In-house 230-277 (284) alignment 
Range on Protein: 3-47
Range on HMM: 230-277/284.0
RIKSEK---LVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLG
... |.    ||... |...|..||.|| ..  |.|...||.|.|||.
qlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklk
0040438 (Phosphotyrosine protein) phosphatases II 3-47 5.9e-09 31.1 In-house 235-279 (317) alignment 
Range on Protein: 3-47
Range on HMM: 235-279/317.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLG
... |. ||... |...|..||..| ..  |.|..||| | || .
qlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 3-48 6.9e-09 30.1 In-house 238-283 (315) alignment 
Range on Protein: 3-48
Range on HMM: 238-283/315.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
... |...|..| .. .|. |  ||    .| ||.|||.|..  | 
qaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgd
0036941 (Phosphotyrosine protein) phosphatases II 3-48 7.1e-09 30.8 In-house 233-281 (297) alignment 
Range on Protein: 3-48
Range on HMM: 233-281/297.0
RIK---SEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
...    |. |||.. |...|..||..| ..  |.|...|| | || ..
qledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkl
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 3-43 1.8e-08 28.8 In-house 199-239 (239) alignment 
Range on Protein: 3-43
Range on HMM: 199-239/239.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
. | .| ||||| |. .|. || ||    .||||| |..||
qakkqktvdifnyvkairedrphmvqtseqyvfihlavlea
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 3-54 2.6e-08 27.8 In-house 238-288 (439) alignment 
Range on Protein: 3-54
Range on HMM: 238-288/439.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEgVAV
..|.|. |||   |...|| |  || .  .||||..|..| .. |.|  |..
qlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdia.vti
Y_phosphatase Protein-tyrosine phosphatase 3-42 3.2e-08 28.7 Pfam-A 196-235 (235) alignment 
Range on Protein: 3-42
Range on HMM: 196-235/235.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVE
....|. ||... |. .||.||.|| .. .|.|...|..|
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
Y_phosphatase Protein-tyrosine phosphatase 3-42 3.2e-08 28.7 In-house 196-235 (235) alignment 
Range on Protein: 3-42
Range on HMM: 196-235/235.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVE
....|. ||... |. .||.||.|| .. .|.|...|..|
qleaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
0039614 (Phosphotyrosine protein) phosphatases II 3-46 3.8e-08 28.6 In-house 248-291 (297) alignment 
Range on Protein: 3-46
Range on HMM: 248-291/297.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKL
....|. ||... |...|..||..|...  |.|..|||.| || 
qlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 3-42 6.3e-08 27.1 In-house 200-239 (239) alignment 
Range on Protein: 3-42
Range on HMM: 200-239/239.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVE
. | .| ||||| |. .|. || ||    .||||| |..|
qakkqktvdifnyvkairedrphmvqtseqyvfihlavle
0045450 (Phosphotyrosine protein) phosphatases II 3-43 2.2e-07 26.4 In-house 260-303 (307) alignment 
Range on Protein: 3-43
Range on HMM: 260-303/307.0
RIKSEKL---VDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
....|.    ||... |...|..|| .| |.  |.|...|| | 
qlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
0042113 (Phosphotyrosine protein) phosphatases II 3-44 6e-07 24.6 In-house 202-243 (245) alignment 
Range on Protein: 3-44
Range on HMM: 202-243/245.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
....|. |.... |...|..||..|...  |.|...|| | |
qlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
0040439 (Phosphotyrosine protein) phosphatases II 3-43 1.3e-06 23.8 In-house 205-245 (249) alignment 
Range on Protein: 3-43
Range on HMM: 205-245/249.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
... |. ||... |...|..||..|.|.  |.|...|| | 
qlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 3-42 8.2e-06 20.2 In-house 198-237 (237) alignment 
Range on Protein: 3-42
Range on HMM: 198-237/237.0
RIKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVE
. | .|.|||.| |. . . || ..  . .|||||....|
qakekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
subfamily_PTPRK_pd Subfamily PTPRK 4-64 5.1e-10 33.7 In-house 237-296 (314) alignment 
Range on Protein: 4-64
Range on HMM: 237-296/314.0
IKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIeGVAVARPKSLEEAS
|. |..||.|| |. .|. .. ||  |  |.||.|...||   |.   . |.. |.|   |
ieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcget.aipvsefkalyles
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 4-53 7.8e-09 29.8 In-house 226-275 (283) alignment 
Range on Protein: 4-53
Range on HMM: 226-275/283.0
IKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGKIEGVA
...| .||.|. |. ||. |.|.| .   | ..|.. .|    |  . .|
altesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaa
0045098 (Phosphotyrosine protein) phosphatases II 4-45 5.5e-07 24.8 In-house 233-273 (278) alignment 
Range on Protein: 4-45
Range on HMM: 233-273/278.0
IksEKLVDIFNNVQYMRKCRPM-MVMNEIEYVFIHDALVEALK
.  |. ||... |...|..||. .|.|.  |.|....|.| |.
l..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
subfamily_CG7180_pd Subfamily CG7180 4-43 1.9e-06 21.7 In-house 250-289 (296) alignment 
Range on Protein: 4-43
Range on HMM: 250-289/296.0
IKSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEA
.. |. ||.|. |. .|. || .| |  || .| | | ||
vekeeevdvFeavktlrrsRpqLvenveeYkyiYdvllea
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 5-48 1e-06 22.4 In-house 155-198 (440) alignment 
Range on Protein: 5-48
Range on HMM: 155-198/440.0
KSEKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEALKLGK
|    .|||. .. ||. || ||    .|.|.|.|..|.|  | 
krsdqidifsfinsmrnnrpqmvqtpeqyafvheavlegllcgd
subfamily_PTPN12_pd Subfamily PTPN12 7-44 4.5e-06 20.8 In-house 240-277 (290) alignment 
Range on Protein: 7-44
Range on HMM: 240-277/290.0
EKLVDIFNNVQYMRKCRPMMVMNEIEYVFIHDALVEAL
.. .|.|. |. .|| |. .|  .  |.... |..| .
peeldvfdlvlelrkqraalvqtkeqyelvykavaelv