Gene C04F12.8 in Caenorhabditis elegans

Synonym: CELE_F13D11.3, F13D11.3

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP14
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP011_AA protein Get Run
CeleP011_AA_8-150 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Slingshot_pd Subfamily Slingshot 6-149 8e-33 107.2 In-house 14-158 (169) alignment
Range on Protein: 6-149
Range on HMM: 14-158/169.0
GVLGQMSEINDHLYLSG-AGVLKPDKIKQRKINMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASL
| | . |.| ||.||       . ...|..... |.| | |  . . . .. ..||. |.. . | ....   . |...|..| | ||||  ||||||| 
gqldsaskifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsast

VMIYLVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLR
|. | .|. ...| .|..|||  | .|.|| ||.||.  ||  |.
viayamkeyglsleealeyvkerrsvikPnkgflkqleeyeGile

0045098 (Phosphotyrosine protein) phosphatases II 8-149 1.9e-27 91.8 In-house 19-272 (278) alignment
Range on Protein: 8-149
Range on HMM: 19-272/278.0
LGQMSEINDHLYLSGAG------------------------------------------VLKPDKIKQRKINMIVNATTEE-------------------
||..|||...|||...                                               . ... .|. ||..|...                   
lgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggslty

------------------------------PSTYMQGVDTMKI-RIEDHPYARLS--EHFDVVADKIRNVKE--------------RGGKTLVHCMAGVS
                              .. .  ||  ...  ..||    |.   .|. . . ||.. .              .||..||||.|||.
gdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGvg

RSASLVMIYLVKHE---HMTLRQAYHYVKAARPI-IRPNVGFWKQMVDYEKRLR
|.. ||..||...    ...| .|.....  ||. . .| ...... ... .|.
RtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllell

subfamily_DSP14_pd Subfamily DSP14 9-160 4.3e-70 228.7 In-house 5-156 (157) alignment
Range on Protein: 9-160
Range on HMM: 5-156/157.0
GQMSEINDHLYLSGAGVLKPDKIKQRKINMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIY
 ..|.|...|.|||...|.....|..||..|.|.|.| |.| .......|...||.| |.|..||| |||||..||..||||||||.|||||||||...|
aalsqitpsLflsgvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclay

LVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLRGTASVKMVQTP
|.|.|...||.||..||.||||||||||||||..||||.|.|..|||||..|
lmkyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgkssvkmvdsp

0044763 (Phosphotyrosine protein) phosphatases II 9-150 6.6e-37 122.2 In-house 21-172 (178) alignment
Range on Protein: 9-150
Range on HMM: 21-172/178.0
GQMSEINDHLYLSGAGVLK-PDKIKQRKINMIVNATTEEPSTYMQG---------VDTMKIRIEDHPYARLSEHFDVVADKIRNVK-ERGGKTLVHCMAG
  .||| ..|||....  . .. .|. .|..||| |.| .  ...          .  ..| |.||.   |.|||. . . |...  |.||..||||.||
inaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaG

VSRSASLVMIYLVKHEHMTLRQAYHYVKAARPiIRPNVGFWKQMVDYEKRLRG
|.||..||..||.|. ...| .|...|...|| | || |...|. ..|.||..
vgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllk

0046846 (Phosphotyrosine protein) phosphatases II 9-149 5e-28 93.4 In-house 10-173 (176) alignment
Range on Protein: 9-149
Range on HMM: 10-173/176.0
GQMSEINDHLYLSGAgvlkP---------------DKIKQRKINMIVNATTEE-----------PSTYMQGVDTMKIRIEDHPYARLsEHFDVVADKIRN
. ...||..|.|...    |               . .|. .|...|| |.|            |  .  |.  . . ..||    | |... . . ||.
ldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefire

VKERGGKTLVHCMAGVSRSASLVMIYLVKH-EHMTLRQAYHYVKAARP-IIRPNVGFWKQMVDYEKRLR
. ..||..||||.||..|.. ||..||...  .... .|...|.. ||  . .. .....  ..|..|.
alkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefellll

subfamily_DSP10_pd Subfamily DSP10 10-151 3.8e-38 124.9 In-house 13-156 (159) alignment
Range on Protein: 10-151
Range on HMM: 13-156/159.0
QMSEINDHLYL-SGAGVLKPDKIKQRKINMIVNATTEEPSTYMQ-GVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMI
..|..  .|.| |. .  . | ... .|....| ||. | .. . ..  ..| ..|     |...|..  . | .....| . ||||.||.||||..|. 
pasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvvia

YLVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLRGT
||.|| ...|..||..|| .|||| ||..|  |....||.|. .
YlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnks

subfamily_DSP19_pd Subfamily DSP19 10-148 1.5e-36 120.0 In-house 11-150 (152) alignment
Range on Protein: 10-148
Range on HMM: 11-150/152.0
QMSEINDHLYLSGAGV-LKPDKIKQRKINMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIY
...|....|||.   |  . ...|..||  |.| .|. | .. . . ...| | |.| ..|..... . | |.....  |  |||| ||||||||.|. |
evgeveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviay

LVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
|.|.|...|..|...|..||| |.|| ||.||. .||..|
lmkkeelsleealelvrearpcikPneGFikqLkeyeael

subfamily_DSP12_pd Subfamily DSP12 10-146 4e-29 96.0 In-house 1-141 (155) alignment
Range on Protein: 10-146
Range on HMM: 1-141/155.0
QMSEINDHLYLSGAGV-LKPDKIKQRKINMIVNATTEEP---STYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLV
..|.|.. |||.|.    .... |. ||. ..  ..||    .. .. |.| .| | |.| . . .|.| . | | .  |..|. ||||.||||||...|
evsrilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiv

MIYLVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEK
. ||.|.|.. | .|.. ||...| |.|| || .|.  .||
iAYlmkkeklslekAlklvkekkpeiepNegFleQLklfek

subfamily_DSP3_pd Subfamily DSP3 10-149 8.1e-27 87.9 In-house 10-158 (162) alignment
Range on Protein: 10-149
Range on HMM: 10-158/162.0
QMSEINDHLYLSGAGVLK-PDKIKQRKINMIVNATTE-------EPSTYM-QGVDTMKIRIEDHPYARLSEHFDVVADKIRN-VKERGGKTLVHCMAGVS
.. |. ..||.... | |  .|.|.  |  ..||.         ... |   ..  . . ..| | . ||..|. .|. |.. .... || ||||..|||
evdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvs

RSASLVMIYLVKHEHMTLRQAYHYVKAARPIiRPNVGFWKQMVDYEKRLR
||| ||. ||. ...||| .| . |.. | | .|| || ||.......|.
RsatlvlayLmirrkmtlveairtvrkkRei.lPneGFlkqLaeldeelk

PTPc_motif_SM00404 11-146 1.3e-39 130.3 In-house 2-139 (140) alignment
Range on Protein: 11-146
Range on HMM: 2-139/140.0
MSEINDHLYLSGAGVLK-PDKIKQRKINMIVNATTEEPSTY-MQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIY
.|.| .||||...   . |...|. .| ...|.|.| . |. ..|.  ..| ..|.  . ||...| |.| |.|....||| ||||.|||||||.|.. |
psrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

LVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEK
| . ....|..||..||  ||||.||..|..|...|||
lmryrqlslaeayefvkerRpiispnlnfvrqLieyek

0048076 (Phosphotyrosine protein) phosphatases II 11-148 2.7e-33 110.0 In-house 4-142 (145) alignment
Range on Protein: 11-148
Range on HMM: 4-142/145.0
MSEINDHLYLSGAGV-LKPDKIKQRKINMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYL
.||| ..|||..  . |. . .|. .| ...| |.|..  . .|.  . . ..||.   |.|... . . |... ..||..||||.|||.|...||..||
pseilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaayl

VKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
.......| .|...|...||.. ||.|..... ..|..|
mlllgvsleealelvrsqrpgavpnpgqlrflyefelel

0041856 (Phosphotyrosine protein) phosphatases II 11-150 2e-31 104.4 In-house 19-174 (182) alignment
Range on Protein: 11-150
Range on HMM: 19-174/182.0
MSEINDHLYLSGAGV---------------LKPDKIKQRKINMIVNATtEEP----STYMQGVDTMKIRIEDHPYARlsehFDVVADKIRNVKERGGKTL
...||..|||..                     . .|...|..|||.| ||.      . .|.  ... ..||.       .| . | |. |.|.||..|
ldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.eelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvl

VHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAARP--IIRPNVGFWKQMVDYEKRLRG
|||.|||.|...||..||.|. ...|..|...|. .||  .|.|| .|. |.. .|..|..
VHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllk

0048179 (Phosphotyrosine protein) phosphatases II 11-148 2.3e-31 103.8 In-house 4-144 (144) alignment
Range on Protein: 11-148
Range on HMM: 4-144/144.0
MSEINDHLYLSGAG-VLKPDKIKQRKINMIVNATTEEPSTYMQ--GVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMI
.||| ..|||..   .|. . .|. .|....| |.| . ...   |.  ... ..||.   |.|... . . |... |.||..||||.|||.|...||..
pseilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaa

YLVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
||.|.....| .|...|...||.. || |..... .|||.|
ylmkklglsleealalvrsrrpgavpnpgqlrfLleyekll

subfamily_DSP15_pd Subfamily DSP15 11-147 3.6e-28 92.6 In-house 2-138 (151) alignment
Range on Protein: 11-147
Range on HMM: 2-138/151.0
MSEINDHLYLSGAGVLK-PDKIKQRKINMIVNATtEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYL
.|..   |||..  . |  ...|...|  |..   ...  ... ..   |...| | | ||..|.   . | . . .... ||||.||||||. ||..||
iskvlpglylgnfrdskdeelLkeknithilsvh.dnakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYl

VKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKR
.   ..  |.| . .|||| .  ||.|| .|. .||| 
mtvtelnwrdalevikaaRsvanPnfGfkrqlkeyekt

0036282 (Phosphotyrosine protein) phosphatases II 11-150 6.4e-26 86.5 In-house 12-171 (174) alignment
Range on Protein: 11-150
Range on HMM: 12-171/174.0
MSEINDHLYLSGAGVLKPDKIKQRKINMIVNATTEEPST---------------YMQGVDTMKIRIEDHPYARLSEhFDVVADKIRNVKER--GGKTLVH
.|.|...|.....     . .|. .|...|. ..|..                 .  |.  ... ..||    ||. .. . . .... ..  ||..|||
lsyitprliagqgplafwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVH

CMAGVSRSASLVMIYLVKHEHM-TLRQAYHYVKAAR---PIIRPNVGFWKQMVDYEKRLRG
|.|||.|.. ||..||... .. .|..|...|...|   | . .. .....  ..|| |.|
CsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekllsg

subfamily_DSP8_pd Subfamily DSP8 12-150 1.9e-28 93.0 In-house 16-156 (159) alignment
Range on Protein: 12-150
Range on HMM: 16-156/159.0
SEINDHLYL-SGAGVLKPDKIKQRKINMIVNATTEEPS-TYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYL
 .| ..||| |   ||. . ...  |....|| .. |.   .. .  ... ..|.   .|.. ||   . |  .|.  |. |||..|| ||||.... |.
trilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiayi

VKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLRG
.|. .|.| .||..||  || | ||. | .|...|||.|. 
mktlemsldeayrfvkekrptispnlnflgqLleyekelkl

subfamily_LRR-DSP_pd Subfamily LRR-DSP 12-150 1.2e-24 80.8 In-house 121-260 (263) alignment
Range on Protein: 12-150
Range on HMM: 121-260/263.0
SEINDHLYLSGAGVLKPD-KIKQRKINMIVNATTEEPSTYMQGVDTMKI-RIEDHPYARLSEHFDVVADKIRNVKERGGkTLVHCMAGVSRSASLVMIYL
.|| |.|.| |    .    .|.  .  |. | ..    . .    . |  ||| . | .| ||. .   | . ...||  |||| ||||||..||. ||
deiidklflGgldsannksilkdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafieeGrkkGG.vlvhcraGvsrsstlvisyl

VKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLRG
.|........|.  |.  || |.|| || .|.  ||| |  
mkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekklfc

subfamily_DSP1_pd Subfamily DSP1 13-149 5.7e-38 124.6 In-house 20-157 (163) alignment
Range on Protein: 13-149
Range on HMM: 20-157/163.0
EINDHLYLSGAGV-LKPDKIKQRKINMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVK
.| |.||| .. |  . . .|. .|  |.|...| . .. .    .|. .||.| | .|..|. | . | .||. .|| |.|| ||.|||..|...||.|
kildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlclaylmk

HEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLR
.....| .|...||  |.||.||.|| .|...|||.| 
tkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkll

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 13-147 6.4e-32 104.1 In-house 9-146 (148) alignment
Range on Protein: 13-147
Range on HMM: 9-146/148.0
EIND-HLYLSG-AGVLKPDKIKQRKINMIVNATTEEPSTY-MQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYL
|| | .|.|      .. ...|.  .  ||||| | . ..  .|.. ......|.|   ||  |. ... .|..|..|.. |||.  |||||. |....|
eikdafLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwl

VKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKR
.......|..|. .|| .|. ..|| || ||. ..|..
idfkrvslkealalvkskrryvdpnlgfLkqLaeleqa

subfamily_DSP6_pd Subfamily DSP6 13-149 1.8e-29 96.3 In-house 16-155 (158) alignment
Range on Protein: 13-149
Range on HMM: 16-155/158.0
EINDHLYLSGAG-VLKPDKIKQRKINMIVNATTEEPSTYMQG--VDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYL
|| ..|||  |    . . .|. ||. ..| |.. |... .   .  ..| ||||  . |...|    . | . ...  | ||||.||.|||  ... ||
eilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlayl

VKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLR
.|.....| .||..||. .. | ||  | .|..|.|..||
mkklalslndaydlvkkrksnisPnfnfmgqlldferslr

PTEN_1 13-149 5e-28 93.2 In-house 43-192 (196) alignment
Range on Protein: 13-149
Range on HMM: 43-192/196.0
EINDHLYLSGAGVLK--PDKIKQRKINMIVNATTEEPS---------TYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKE--RGGKTLVHCMAGVS
|| ..||.  .  .    |  |...| ..|| . ||.           . .||   .. ||||.   |||.||.... |  ...  .|.. |||| ||..
eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlg

RSASLVMIYLVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLR
||. .|. ||.... .| ..|  .|...|| ..|| ..... . |...|.
RsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaell

0037934 (Phosphotyrosine protein) phosphatases II 13-147 3.4e-26 87.7 In-house 41-240 (243) alignment
Range on Protein: 13-147
Range on HMM: 41-240/243.0
EINDHLYLSGAG---------VLKPDKIKQRKINMIVNATTEE---------------------------------------------PSTYMQGVDTMK
.. ..|.....              . ... .|..||. |...                                             .  . ...  . 
yvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyhy

IRIEDH---P-YARLSEHFDVVADKIRN-----VKERGGKTLVHCMAGVSRSASLVMIYLVKHE-HMTLRQAYHYVKAARPI-IRPNVGFWKQMVDYEKR
. . ||   .  . | ...| | . |..     .  .||..||||.|||.|.. |...||...  ...| .|...... ||  . .. .....  .... 
lpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyealle





0042113 (Phosphotyrosine protein) phosphatases II 14-147 3.7e-23 77.7 In-house 50-241 (245) alignment
Range on Protein: 14-147
Range on HMM: 50-241/245.0
INDHLYLSGAGVLKPDK-----IKQRKINMIVNATTEE----------------------------------------------PSTYMQGVDTMKIRIE
|.........   .  .     ... .|..||. |.||                                               . . ...  . . ..
itpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwp

DHPYARLSEHFDVVADKIRNVKE--RGGKTLVHCMAGVSRSASLVMIYLV-----KHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKR
||. . |.|... . . .|.. .  ..|..||||.|||.|.. ....||.     |.  ..| .|.....  || .... ...... .... 
dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle

subfamily_MKPLT_pd Subfamily MKPLT 15-148 5.9e-27 88.2 In-house 26-160 (164) alignment
Range on Protein: 15-148
Range on HMM: 26-160/164.0
NDHLYLSGAGVLKPDKI-KQRKINMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHE
.|.|||  |   . .|. |. ||. ||| ..|. . . . |. .....|| .  .||.... .|. . .  . ||. ||||  |.|||.|  . .|.| .
edtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLiksk

HMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
  ||..||.|.|  | |..|| || ||.  .|. .
gwtlkeayeylkerrsivapnrGflkqlakfeeli

subfamily_MKPLV_pd Subfamily MKPLV 15-148 5.9e-27 88.2 In-house 26-160 (164) alignment
Range on Protein: 15-148
Range on HMM: 26-160/164.0
NDHLYLSGAGVLKPDKI-KQRKINMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHE
.|.|||  |   . .|. |. ||. ||| ..|. . . . |. .....|| .  .||.... .|. . .  . ||. ||||  |.|||.|  . .|.| .
edtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLiksk

HMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
  ||..||.|.|  | |..|| || ||.  .|. .
gwtlkeayeylkerrsivapnrGflkqlakfeeli

0051429 (Phosphotyrosine protein) phosphatases II 16-148 1.8e-19 65.9 In-house 22-224 (272) alignment
Range on Protein: 16-148
Range on HMM: 22-224/272.0
DHLYLSGA----GVLKPDKIKQRKINMIVNATTEEP------STYMQGVDTMKIRIEDHPYARLSEHF--------------------------------
. ||.||.     .   ...|. .|..||. ..||       . | .|.. . . |.|. . . . ..                                
grlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsageare

----------------DVVADKIRNVKErGGKTLVHCMAGVSRSASLVMIYLVKhEHMT--------------LRQAYHYVKAARPIIRPNVGFWKQMVD
                . . . .. . . ||. ||||.||..|.. .|...|.  . ..              |..|.....|.|| .... .....  .
vmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflye

YEKRL
... |
allel

DSPc Dual specificity phosphatase, catalytic domain 18-146 5.5e-36 118.4 Pfam-A 1-132 (133) alignment
Range on Protein: 18-146
Range on HMM: 1-132/133.0
LYLSGAGVLKPDKIKQRKINMIVNATTEEPS---TYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEH
|||...   ....... .|....|.|.| |      ..  . ..| .||.  . .|.... . . |......|.| ||||.||.||||.|.. || | ..
lylgskstaslalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktkn

MTLRQAYHYVKAARPIIRPNVGFWKQMVDYEK
..|..||..||  |..|.||.||..|...||.
lslneAyefvkerrskispnagflrqLleyer

DSPc Dual specificity phosphatase, catalytic domain 18-146 5.5e-36 118.4 In-house 1-132 (133) alignment
Range on Protein: 18-146
Range on HMM: 1-132/133.0
LYLSGAGVLKPDKIKQRKINMIVNATTEEPS---TYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEH
|||...   ....... .|....|.|.| |      ..  . ..| .||.  . .|.... . . |......|.| ||||.||.||||.|.. || | ..
lylgskstaslalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktkn

MTLRQAYHYVKAARPIIRPNVGFWKQMVDYEK
..|..||..||  |..|.||.||..|...||.
lslneAyefvkerrskispnagflrqLleyer

0045450 (Phosphotyrosine protein) phosphatases II 19-147 6.7e-26 87.2 In-house 97-302 (307) alignment
Range on Protein: 19-147
Range on HMM: 97-302/307.0
YLSGAGVLKPDK------------------IKQRKINMIVNATTEEPST----------------------------YMQGVDTMKIRIEDH--------
.| . |  ...|                  ... ....||. |.... .                            ...|.  ......|.        
lllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrt

---------PYARLSEHFDVVADKIRNVKE------RGGKTLVHCMAGVSRSASLVMIYLVKHEH--------MTLRQAYHYVKAARPIIRPNVGFWKQM
         |   ....|. . | |. |..      .||..||||.|||.|.......||... .        ..|..|...... || . .| ..... 
vthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrfl

VDYEKR
 .... 
yealle

0051082 (Phosphotyrosine protein) phosphatases II 28-145 3.8e-23 77.2 In-house 26-150 (151) alignment
Range on Protein: 28-145
Range on HMM: 26-150/151.0
PDKIKQRKINMIVNATTEEPSTYMQ------GVDTMKIRIEDHPYARLSEHFDVVADKIRNVKER-GGKTLVHCMAGVSRSASLVMIYLVKhEHMTLRQA
 . .|. .|..||| ..||.  |.       |.. . | |.|.|   |...|| |.. .. . .  .|..||||.||..|.. ||..||.. ....| .|
lellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lgvsleea

YHYVKAARP-IIRPNVGFWKQMVDYE
...... || ...|| .|..|. ...
leeyrlkrpgvvqpnqqflfqlfall

0038934 (Phosphotyrosine protein) phosphatases II 29-149 2.4e-21 71.7 In-house 50-177 (194) alignment
Range on Protein: 29-149
Range on HMM: 50-177/194.0
DKIKQRKINMIVNATTEEPSTYMQ-----GVDTMKIRIEDH---PYARLSEHFDVVADKIRNvKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQA
 | ...|. .... | .|.    .     |.. .|. ..|.   |   .  .|  ..|.. | .  ||. .|||.||..|.. ||  ||... .|....|
lkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefln.edpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeA

YHYVKAARPIIRPNVGFWKQMVDYEKRLR
..... .|| . ||........ . | ||
ialfrekRpgaipnqdyleallkrykelr

0043147 (Phosphotyrosine protein) phosphatases II 30-149 2.1e-30 101.1 In-house 39-161 (172) alignment
Range on Protein: 30-149
Range on HMM: 39-161/172.0
KIKQRKINMIVNATTE---EPSTYMQGVDTMKIRIEDHPYArLSEHFDVVADKIRN--VKERGGKTLVHCMAGVSRSASLVMIYLVKhEHMTLRQAYHYV
 .|...|..|||.|..    .  . .|.  . . ..||.   |.|... . . |..  ....||..||||.|||.|.. ||..||.. ....| .|...|
mlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalv

KAARPIIRPNVGFWKQMVDYEKRLR
...||.. .| .....  ..||.|.
rekRpgavqnpsqyrflyyfeklll

0049260 (Phosphotyrosine protein) phosphatases II 30-149 2.1e-27 91.1 In-house 28-150 (152) alignment
Range on Protein: 30-149
Range on HMM: 28-150/152.0
KIKQRKINMIVNATTEEPSTY---MQGVDTMKIRIEDHPYARLSEHFDVVADKIRN-VKERGGKTLVHCMAGVSRSASLVMIYLVKhEHMTLRQAYHYVK
 .|. .|. ||. |.... ..    |.   . . ..||.   ||.... . . |.   ...||..||||.|||.|.. ||..||..  ...| .|. .|.
mlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleeavalvr

AARPIIRPNVGFWKQMVDYEKRLR
..||.. || |....  ..|| |.
ekRpgavpnpgqlrflyefekllk

0040438 (Phosphotyrosine protein) phosphatases II 31-149 7.1e-26 86.6 In-house 106-276 (317) alignment
Range on Protein: 31-149
Range on HMM: 106-276/317.0
IKQRKINMIVNATTEEPST---------------------------YMQGVDTMKIRIEDH----------------PYARLSEHFDVVADKIRNVKER-
... ....||. |..|.                             ...|.   ....||.                |   . ...| . | .. |.|  
vweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreal

---GGKTLVHCMAGVSRSASLVMIYLV-----KHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLR
   ||..||||.|||.|.......||.     |...... .|.......|| . .. ...... |..  . 
edpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl

0040439 (Phosphotyrosine protein) phosphatases II 31-148 3.6e-25 84.4 In-house 74-245 (249) alignment
Range on Protein: 31-148
Range on HMM: 74-245/249.0
IKQRKINMIVNATTEEPS-------------------------------------------TYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKE--
... .|..||..|....                                             . . .  . |.. | |   ....|. . | |. |..  
lwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkal

----RGGKTLVHCMAGVSRSASLVMIYLV-----KHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
    .||..||||.|||.|.. ....||.     |. ...| .|..... .|| . .| .....  .....|
eelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel

0039614 (Phosphotyrosine protein) phosphatases II 31-149 1.2e-22 76.2 In-house 121-289 (297) alignment
Range on Protein: 31-149
Range on HMM: 121-289/297.0
IKQRKINMIVNATTEEPST-------------------YMQGVDTMKIRI-----------------------EDHPYARLSEHFDVVADKIRNVKE---
... ....||. |....                     .. .|.. .  .                        ||    ..|... . ...|.. .   
vweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelp

RGGKTLVHCMAGVSRSASLVMIYLV-----KHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRLR
.||..||||.|||.|.......||.     |. .... .|..... .|| .... .....  |... |.
kggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallell

0036941 (Phosphotyrosine protein) phosphatases II 31-148 7.7e-22 73.4 In-house 98-276 (297) alignment
Range on Protein: 31-148
Range on HMM: 98-276/297.0
IKQRKINMIVNATTEEPSTY-------------------------------MQGVDTMKIRIED----------------HPYARLSEHFDVVADKIRNV
. . ....||. |....                                   ... . .....|                 |   . |... . | |. |
vweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielv

KE------RGGKTLVHCMAGVSRSASLVMIYLV--------KHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
..      .||..||||.|||.||.......|.        |.. ... .|.....  || . ......... ...  |
rkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallel

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 31-149 7.5e-21 68.1 In-house 24-153 (154) alignment
Range on Protein: 31-149
Range on HMM: 24-153/154.0
IKQRKINMIVNATTEEPSTYMQG---------VDTMKIRIEDHPYARLSEHFDVVADKIRNVK--ERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQ
.....|. |.|  .  .  . .          .. ..... |..   . |..| . . |..     . .| |||. .||||||.|.. ||... ...| .
lqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaallisylmdklkislsl

AYHYVKAARPIIRPNVGFWKQMVDYEKRLR
|.  .| .|.||.|| || ||.  .||.|.
alellkdsryiikPnqGflkqleifekell

0043336 (Phosphotyrosine protein) phosphatases II 31-145 1.3e-18 62.9 In-house 108-273 (278) alignment
Range on Protein: 31-145
Range on HMM: 108-273/278.0
IKQRKINMIVNATTEE---------------------------------------------PSTYMQGVDTMKIRIEDHPYA-RLSEHFDVVADKIRNVK
... ....||. |...                                              . . ...    . . ||     || ..| . . .. ..
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale

ERGGKTLVHCMAGVSRSASLVMIYLV-----KHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYE
 ..|..||||.|||.|.. ....||.     |. ...| .|.....  || . ..  ....  ...
dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal

0047943 (Phosphotyrosine protein) phosphatases II 31-141 2.2e-14 49.0 In-house 97-264 (273) alignment
Range on Protein: 31-141
Range on HMM: 97-264/273.0
IKQRKINMIVNATTEEPSTY------------------------------MQGVDTMKIRIED----------------HPYARLSEHFDVVADKIRNVK
... ....||  |...                                   ... . ......                 |     .... . . |. |.
vweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvr

E------RGGKTLVHCMAGVSRSASLVMIYLV-----KHEHMTLRQAYHYVKAARPIIRPNVGFWKQM
.      ..|...|||.|||.|........|.     |.  ... .|.....  || . ... .....
kalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl

subfamily_RNGTT_pd Subfamily RNGTT 31-129 8.5e-08 26.1 In-house 50-155 (189) alignment
Range on Protein: 31-129
Range on HMM: 50-155/189.0
IKQRKINMIVNATTEEPSTYM-----QGVDTMKIRIEDH---PYARLSEHFDVVADKIRNvKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYH
 .. |. .... | ...         .|. ..|.... .   | |   ..|  . ..  . |.      |||  |  |.  |.. |||..|.. ...| .
tlkvklglvidltntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffk.knpeevigvhCthGfnRtGFlivsyLvekedwsveaava

YVKAARP
  . |||
lFakaRp

subfamily_PRL_pd Subfamily PRL 31-128 9.3e-06 19.8 In-house 30-130 (151) alignment
Range on Protein: 31-128
Range on HMM: 30-130/151.0
IKQRKINMIVNATteEPSTYMQGVDTMKIRIEDHPYAR--------LSEHFDVVADKIRnvkERGG-KTLVHCMAGVSRSASLVMIYLVKhEHMTLRQAY
.|..... .| .   ||.   . ...  |.. | ...         . | .... .| .   |...    |||.||. |.  || . |.  . |. ..| 
lkkeevktvvrvc..eptydteklekegievldlafddGavPpeevveeWlellkekfk...eepkstvavhcvaGlGraPvlvalalie.aGmkyedav

HYVKAAR
....  |
efirekr

0049772 (Phosphotyrosine protein) phosphatases II 32-148 5e-28 94.1 In-house 167-273 (314) alignment
Range on Protein: 32-148
Range on HMM: 167-273/314.0
KqrkinmivNATTEEPSTYMQGVDTMKIRIEDhPYARLSEHFDVVADKIRNVkERGGKTLVHCMAGVSRSAS-LVMIYLVKHEHMTLRQAYHYVKAARPi
|        . ... .    .|.  . | ..| . | |.|.|| . . |... ..||..||||.||..|... .|. ||.|. ...|..|...|...|| 
k........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.

IRPNVGFWKQMVDYEKRL
|.|| ||..|  .||..|
inpnpgfieqleqyefil

subfamily_STYXL1_pd Subfamily STYXL1 32-150 1.2e-20 67.3 In-house 34-155 (157) alignment
Range on Protein: 32-150
Range on HMM: 34-155/157.0
KQRKINMIVNATTEEPSTYMQ---GVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAAR
|  |.   || ...    .      .. ..|..||.. | | |... . . | . |..|   ||    |.||||.... ||. ....||..||.|.|  .
kdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkaykylkkCk

PIIRPNVGFWKQMVDYEKRLRG
. ..|| .| .|. ..||.| |
envkPnrafveqlseWekqllg

0051299 (Phosphotyrosine protein) phosphatases II 32-135 1.2e-12 43.4 In-house 113-272 (288) alignment
Range on Protein: 32-135
Range on HMM: 113-272/288.0
KQRKINMIVNATTEEPS---------------------------TYMQGVDTMKIRIEDH--------------------PYARLSEHFDVVADKIRNVK
 . ....||  |...                             . .... . .......                    |     .... . | .| |.
weqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvr

ER----GGKTLVHCMAGVSRSASLVMIYLV-----KHEHMTLRQAYHYVKAARPIIRPNV
.     || ..|||.|||.|.. .....|.     |...... .|.....  || . ...
kalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtp

0050432 (Phosphotyrosine protein) phosphatases II 32-134 2.4e-12 42.2 In-house 129-284 (308) alignment
Range on Protein: 32-134
Range on HMM: 129-284/308.0
KQRKINMIVNATTEEPST----------------YMQG--------------VDTMKIRIED----------------HPYARLSEHFDVVADKIRNVKE
 . ....||  |...                   .. |              . . ......                 |     .... . | .. |..
weqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrk

R--GGKTLVHCMAGVSRSASLVMIYLV-----KHEHMTLRQAYHYVKAARPIIRPN
.  ||...|||.|||.|.. .....|.     |. .... .|.....  ||   ..
slpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqt

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 34-149 7.3e-24 77.5 In-house 27-142 (145) alignment
Range on Protein: 34-149
Range on HMM: 27-142/145.0
RKINMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAARPIIRP
| .||    .    ... . .... |  ||     ||.||| |.| |   || |   .|||||||||| .. . .|.|.  ||| .|   |.. |    |
rivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarqvrsnrllayp

NVGFWKQMVDYEKRLR
|| | |.... ||.|.
nvtflknllnlekqlk

subfamily_MSG5_pd Subfamily MSG5 36-148 4.3e-16 52.5 In-house 48-160 (165) alignment
Range on Protein: 36-148
Range on HMM: 48-160/165.0
INMIVNATTEEPSTYMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAARPIIRPNV
.....| . | .   ..        || .  ...   .  ..  |   . .. | ||||  |.||||||.. |..|.  ..||.||. .|.    | |..
fdlvinvakeindlellvpavkyyhiewehdskivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsi

GFWKQMVDYEKRL
|.  |....|  |
glifqlmeweval

subfamily_DSP23_pd Subfamily DSP23 40-136 4.3e-08 27.9 In-house 36-133 (148) alignment
Range on Protein: 40-136
Range on HMM: 36-133/148.0
VNATTE--EPSTYMQGVDTMKIRIEDHPYARlSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAARPIIRPNVG
|  |.|   ..  . ..  ...||.|.      |  .     . . .|..    |||. |  |. ...  ||||.....  .|   |.  ||     | 
vslteegrphveatpnltlvrlriddyhppa.leqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpgsvetve

subfamily_PTPMT1_pd Subfamily PTPMT1 50-148 3.1e-16 54.3 In-house 70-168 (171) alignment
Range on Protein: 50-148
Range on HMM: 70-168/171.0
YMQGVDTMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
  .||. ..... |.  |   |.     . |..|...| .  ||| || .|||.||  ||.|.|.... .| ...|. |.||| .   ||..  ||. |
kklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekl

subfamily_PTPDC1_pd Subfamily PTPDC1 52-129 2e-08 28.9 In-house 81-156 (182) alignment
Range on Protein: 52-129
Range on HMM: 81-156/182.0
QGVDTMKIRIEDHPYARLSEHFDVVadKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAARP
||.  ... ..|.  | | . .|.|  |. .   . ||. ||| ||  |   |.  ||| ....|  .| . |.. ||
qgiyvynfgwkDygvasleriLdiv..kvvafalqegkvavhChaGlGrtGvliacylvyakrltaekaiklvrskrp

subfamily_STYX_pd Subfamily STYX 56-148 4.3e-18 58.9 In-house 65-157 (166) alignment
Range on Protein: 56-148
Range on HMM: 65-157/166.0
TMKIRIEDHPYARLSEHFDVVADKIRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMVDYEKRL
 . . . | .   .  ..  | . | .  ..||| |||  ||.||||.||. |...   .  |.|..||.  |  | || || .|. .||   
ylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyeaiy

0046845 (Phosphotyrosine protein) phosphatases II 62-130 4e-11 38.3 In-house 176-255 (284) alignment
Range on Protein: 62-130
Range on HMM: 176-255/284.0
EDHPYARLSEHFDVVADKIRNVKER---GGKTLVHCMAGVSRSASLVMIYLVKHE--------HMTLRQAYHYVKAARPI
 ||     .|..    ...|.. |.   ||...|||.|||.|.. .....|...         .... .|.....  || 
pdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpg

Y_phosphatase Protein-tyrosine phosphatase 71-111 6.4e-06 21.1 Pfam-A 150-194 (235) alignment
Range on Protein: 71-111
Range on HMM: 150-194/235.0
EHFDVVADKIRNVKERG----GKTLVHCMAGVSRSASLVMIYLVK
|. . . | ||.|...     |...|||.|||.|....|.. .. 
espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill

Y_phosphatase Protein-tyrosine phosphatase 71-111 6.4e-06 21.1 In-house 150-194 (235) alignment
Range on Protein: 71-111
Range on HMM: 150-194/235.0
EHFDVVADKIRNVKERG----GKTLVHCMAGVSRSASLVMIYLVK
|. . . | ||.|...     |...|||.|||.|....|.. .. 
espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldill

0048567 (Phosphotyrosine protein) phosphatases II 73-142 5.9e-11 37.0 In-house 60-132 (157) alignment
Range on Protein: 73-142
Range on HMM: 60-132/157.0
FDVVADKIRNVKERGGKTLVHCMAGV---SRSASLVMIYLVKHEHMTLRQAYHYVKAARPIIRPNVGFWKQMV
. .. .... ....|..  ||| ||    .|.| |.  ||..| ..| ..|..... .|| . |    .    
ilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasylls

PTPc_DSPc_SM00012 79-114 1.2e-07 27.2 In-house 28-66 (105) alignment
Range on Protein: 79-114
Range on HMM: 28-66/105.0
KIRNVK----ErGGKTLVHCMAGVSRSASLVMIYLVKHEH
.....|    . .. ..||| |||.|.. .|..... . .
avkknknkses.skpvvVhCsaGvgRtgtfvaldillqql

subfamily_CDC14_pd Subfamily CDC14 80-129 1.3e-07 25.8 In-house 256-305 (328) alignment
Range on Protein: 80-129
Range on HMM: 256-305/328.0
IRNVKERGGKTLVHCMAGVSRSASLVMIYLVKHEHMTLRQAYHYVKAARP
.. ...  |.  ||| ||. |  .|.  ||.|| ..|  .|  ... .||
leiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrP

subfamily_Laforin_pd Subfamily Laforin 82-131 2.2e-06 20.7 In-house 105-154 (183) alignment
Range on Protein: 82-131
Range on HMM: 105-154/183.0
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