Gene C13C4.4 in Caenorhabditis elegans

Synonym: CELE_K08B12.3, CELE_K08B12.3

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily LHPP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP016_AA protein Get Run
CeleP016_AA_7-259 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Chronophin_1 9-254 4.6e-31 99.2 In-house 3-254 (261) alignment 
Range on Protein: 9-254
Range on HMM: 3-254/261.0
GFLLDITGVLYNsiyksDGVAVPKSAEAVNFLYQHS-KVKFLSNAKGNSNRNVARRLQRLGIN-VREEDVITPAPVVAQYCRENKLRPHLFV--RDDVLE
 .|||. |||..     .. |||. ||... | |.  .| |..|   . ....| ||.|||.. |..| ... |   |.. |..... . .|   . . .
lvLlDldGVlik.....geeavpgAaeliealkqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrqqaakakvyvlGeeglrk

YF--DGIDTS-----SPNCVVMGEvEEGFSFDRINRAFRILIDMpkPLLITMGNGKFFQRVDGPCIDVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNA
 .  .|. .      ... ||.|. .| .||.....| . . |    |..   . . . . .|.    |. |||..  .. | | .|||... ||. .. 
elreaGlrlvdepedrveaVvvGy.deelsfeklaeaialirdg..alfvatnrDptvPleeGiaPgtGslaaaveaAsgreplvvGKPepvmfeealek

LGMKPEEIVMVGDDLMSDVGGAQACGMRGVQVRTGK-WRPDFEKM--PVTPDLTADCLYD
 |..||| ||||| |  |.  .. .|.. . |.||   . . ...  ...||  .. . |
igadpeetvmvGDRldTDilagaraglstllvltGvseleeaqaykkdlrPdavvesiad
subfamily_LHPP_pd Subfamily LHPP 10-240 1.5e-94 307.2 In-house 1-227 (227) alignment 
Range on Protein: 10-240
Range on HMM: 1-227/227.0
FLLDITGVLYNsiyksDGVAVPKSAEAVNFLYQHS-KVKFLSNAKGNSNRNVARRLQRLGINVREEDVITPAPVVAQYCRENKLRPHLFVRDDVLEYFDG
.|||..|||.|     ...|.|...||...|.|.. ||.|..|.. .|.|....||.|||..|.||...|......|..||.||||.|.|.||| |.|..
vllDlsGvlhn.....edaaipgavealkrLrqagvkvrfvtNttkeskralverLirlgfdveeeeiftsleaarqllrerklrpyllveddveedfed

IDTSSPNCVVMGEVEEGFSFDRINRAFRILIDMPKPLLITMGNGKFFQRVDGPCIDVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNALGMKPEEIVMV
|||..||.||.|...| |.....|.|||.|....|. ||....||...| || ....|||..||...|.... ..||||...||.....||..|||.||.
idtdkpnavviglapesfeyetlnqafrllleakkakliainkgkyykrkdGlalgpGafvkaleyatgvkaevvGKPsalffekaleelgvdpeeavmi

GDDLMSDVGGAQACGMRGVQVRTGKWRPDFEK
|||...||.||...|.|||.|.|||.||..||
GDdvedDveGAlkaGlrgvlVktGkfrpedek
Hydrolase_6 Haloacid dehalogenase-like hydrolase 10-91 1.3e-16 51.9 Pfam-A 1-78 (101) alignment 
Range on Protein: 10-91
Range on HMM: 1-78/101.0
FLLDITGVLYNsiyksDGVAVPKSAEAVNFLYQH-SKVKFLSNAKGNSNRNVARRLQRLGINVREEDVITPAPVVAQYCRENK
||.|. |||..     .  |.|..|||...| ..  .| .|.|  ..|....| .|..||..| ||.|.|.| ..|.| ...|
flfDvdGvLwr.....gdkaipgaaealkalraagkpvvllTNnsskseeeyakkleklgvdvteeqvvtsataaaeylkkrk
subfamily_PGP_pd Subfamily PGP 10-98 1.3e-12 38.6 In-house 2-87 (279) alignment 
Range on Protein: 10-98
Range on HMM: 2-87/279.0
FLLDITGVLYNSiyksdGVAVPKSAEAVNFLYQHSK-VKFLSNAKGNSNRNVARRLQRLGIN-VREEDVITPAPVVAQYCRENKLRPHLFV
.|.|. ||| ..       |.|..|||.| | .. | | |..|   .|..........||.. |.||.....| ..|.| ...| . . .|
vlfDcDGVlWlg.....etaipgaaealnaLkklgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyv
Chronophin_2 10-90 4.2e-06 17.2 In-house 3-80 (282) alignment 
Range on Protein: 10-90
Range on HMM: 3-80/282.0
FLLDITGVLYNSiyksdGVAVPKSAEAVNFLYQHSK-VKFLSNAKGNSNRNVARRLQRLGI-NVREEDVITPAPVVAQYCREN
 |.|  ||..|        ||. ..| |. | .. | | |..|    .  |..... |||. .|..|.... |   |.| |. 
vlfdcdgviwng.....ekavagapevvsrlaragknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdv
subfamily_PGP_pd Subfamily PGP 113-256 1.3e-18 58.3 In-house 129-276 (279) alignment 
Range on Protein: 113-256
Range on HMM: 129-276/279.0
SPNCVVMGeVEEGFSFDRINRAFRILIDMPkPLLITMGNGKFFQRVDG-PCIDVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNALGMKPEEIVMVGDD
. ..||.| |.| .|. .. .| ..| .    |...  . ....  ..    . |...||.. ... . | .|||... .|  ...  ..||  .|.|| 
dvgAVvvg.vdeklsyakllkAanyLrepe.vlflatneDallplkkevvipgaGslvaaieaasgrkplvlGKPnelllelllekeeidpertlmiGDr

LMSDVGGAQACGMRGVQVRTGKWR-PDFEKMPV----TPDLTADCLYDAV
| .|.  ...||.. . | .|  .  | |..      .||. .|.| | .
lktDilfgkncGlqtLlvlsGvtkledveeikkeeklvPdyyldsladll
Chronophin_2 116-232 2.6e-13 40.9 In-house 128-243 (282) alignment 
Range on Protein: 116-232
Range on HMM: 128-243/282.0
CVVMGeVEEGFSFDRINRAFRILIDmPKPLLITMGNGKFFQRVDGPCI-DVGAFAAALKFSTNCEVLNIGKPSRFYFEQGMNALGMKPEEIVMVGDDLMS
 |..|  .| ..| .. .|   | | .. ||..  .  .    ||  .   |...|||. ... . . ||||||| ||   . . . | . .|.|| | .
avlvg.ydekltflklakacaylrd.adclllatdrdpwhplsdgritpgsgsltaaletasgrkatvigkpsrfmfecissqfsvdparslmigdrlet

DVGGAQACGMRGVQVRTG
|.   . ||.  |   ||
dilfgsncglstvltltg
Hydrolase haloacid dehalogenase-like hydrolase 168-223 4.9e-07 21.7 Pfam-A 176-215 (215) alignment 
Range on Protein: 168-223
Range on HMM: 176-215/215.0
FaaalkfstncevlniGKPSRFYFEQGMNALGMKPEEIVMVGDDLmSDVGGAQACG
.               |||.  .|.. . .|. .|.|..||||..  |. ...|.|
v...............gkPepklfvaaieeLqidpgevamvGDgv.nDapalaaAg
HAD_2 Haloacid dehalogenase-like hydrolase 178-229 1e-10 33.5 Pfam-A 126-176 (176) alignment 
Range on Protein: 178-229
Range on HMM: 126-176/176.0
CEVLNIGKPSRFYFEQGMNALGMKPEEIVMVGDDLmSDVGGAQACGMRGVQV
..  .  ||.  ..|. .. ||.|||||....| | .|| .|.|.|.|.|.|
sddvgapKpdpeayekvlerlgvkpeeilfidDsl.edveaAraaGirtvhv
Hydrolase_like HAD-hyrolase-like 183-255 1.7e-17 54.4 Pfam-A 2-75 (75) alignment 
Range on Protein: 183-255
Range on HMM: 2-75/75.0
IGKPSRFYFEQGMNALGMKPEEIVMVGDDLMSDVGGAQACGMRGVQVRTGKWRPDF-EKMPVTPDLTADCLYDA
.|||... ... .. || .|.|.||.||.| .|. .|...|.| . |.||  |..  .. . .|| ..| |..|
lgKPnpgmydkalevlgappsevvmiGDslatDieaAnnaGirsilVltGvsreedlklakakpdyvvddleea
CECR5_TIGR01456 203-259 1.2e-06 18.1 In-house 302-358 (370) alignment 
Range on Protein: 203-259
Range on HMM: 302-358/370.0
EEIVMVGDDLMSDVGGAQACGMRGVQVRTGKWRPDFEKMPVTPDLTADCLYDAVKLI
 .. ||||. .||. ||.  |.  . |.|| .    |   . ..|  |   .||. |
kklymvGDnPasDiiGarnaGlfsilvktgvydgadelkegkarlvvdsvseaviki