Gene C34B7.2 in Caenorhabditis elegans

Synonym: CELE_C34B7.2, C34B7.2

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily FIG4
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP032_AA protein Get Run
CeleP032_AA_217-572 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_FIG4_pd Subfamily FIG4 9-602 6e-247 811.5 In-house 2-567 (569) alignment 
Range on Protein: 9-602
Range on HMM: 2-567/569.0
TVYETKSRFYIIGCDSTGSRYNVLKIDRIDPKALITGEPEYDYTREEILELLATISDGSSVvyrssskkgtksgLIERATNAFGILGCVRFVEGYYLIII
..||||.|.|..| ... ... ||||||. .. |.  | . ..|..|| ||||......                .|....|.||||.|||.||||||..
vlyetkarlylvGsnkretkfrvlkidrtverelvvledkveftkneikellasleeanrd.............glekkvsayGilGfvrflegyylilv

TRAHAVATLGYHPVYKIVEVAMIPIAMDGV--STSSEEQKYVKLFQSVDLSTDFYFSYSYDMSRTFQENSLRSDWNNHGQR------------RLEADER
|....||..|.| .||| ..|.|.|..| .  ..||.|..|.|||..|||...||||||||..||.|.|.|.||.|.. ..            .|.|.|.
tkrkkvaviGghaiykiedialikitedskksekssdearylklfkdvdltknfyfsysydltrtlqtnlllsdsnrekekaedrvditieakkldanek

FVWNSFLLEPLRKNLISERWFVEIVHGYVRQEYIFLPIGRISLTIIGRRSTKYAGTRFLKRGANPTGNVANYVETEQIVwDMASSGNVADGRFSSFVQMR
||||.||||||.... ...|..||.||.|.|..|.. . .|..|.|.|||.|.||.||||||.| .|.|||.||||||| ..||.|.....|.|||||.|
fvWnnflleplkdtvktfdWlleiihGfvsqskisvlgksiyvtliarrsskfaGarflkrGvnnkGdvaneveteqiv.heasegsldsdryssfvqlr

GSVPMRWSQDPStrGVVGKPLILIDNHEPHAQTAASHFRDVRNKYGNPIVIMNLIKRNEKRRHEGVLHTQFLKNIEYLNQFLPNEEKLCYISFDVARCNK
||||..|||| |   .|.|| | ||...|.|..||.||.|....||.||.|.||.|..|||..| .|...| ..|||||.|||.|.||.|||.|.||..|
GsvPlyWsqdas..klvtkPpikidvvdPfasaaalhfddlfqryGspiiilnlvkkkekrkresilleefeaaieylneflPeekklkyiswdmarask

AANSmpsiNVLNVMEDLSMKSILKNGWFQSFPLSEALKirpreafatldahhskdgrfmIQHGICRTNCVDCLDRTNVAQFVIAKVALGCQLCAMGILDE
....    |||.|.|....||. |.|.|.| | .|. |                     ||.||.||||||||||||.|||||.|||||.||...||.||
skee....nvlevlekyaeksvkktGiflsapdlestk.....................iqeGivrtnCvdcldrtnaaqfvigkvalgyqlkslGiide

PNLTLQSEVCRLLEDMFDEHGDTMALQYAGSQLVHSIKTYKKTAAFQERRRDVFQTLSRYYSNTFNDWDKQMAINLFLGVFRPrITTMKNLWDLTSDYNL
..|...|.|.||||......|||.||||.|||||..||||.|.|......||...||.|||||.|.|.|||.||||||||..|  .....||.|..|..|
sklefdsdvvrlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainlflGvysp.reglpslWeletdfyl

HFPYSLKI
|. ||||.
hnayslkl
Sac_COG5329 76-600 1.4e-99 325.6 In-house 47-543 (1070) alignment 
Range on Protein: 76-600
Range on HMM: 47-543/1070.0
KKGTKSGLIERATNAFGILGCVRFVEGYYLIIITRAHAV-ATLGYHPVYKIVEVAMIPIAMDGVSTSSE---EQKYVKL--------FQSVDLSTDFYFS
.|...   .. | . .|.|| . . . ..||.|| .  | .  . ...||| .| .|..  .    . .   |... ||        .. ..    ||||
lkkegfrslssaheiygvlGlielegslflivitgkskvaqvipgetiykilavdfislnnnkwddeeiesdeasteklrsehpcselkkLlsngsFYfS

YSYDMSRTFQENsLRsdwNNHGQRRLEADERFVWNSFLLEPLRKNL-----IS------ERWFVEIVHGYVRQEYIFLPIGRISLTIIGRRSTKYAGTRF
. .|.. |.|.. |.   ...  .  .|||.|.||||||| | ..      ..      ..... ...|.. .  | .    |.||.| |||.| |||||
tdfditntLqkr.lk...eelelsvdtadeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRf

LKRGANPTGNVANYVETEQIVWDMassgnvadGRFSSFVQMRGSVPMRWSQDpSTRGVvGKPLILIDNHEPHAQTAASHFRDVRNKYGNpIVIMNLIKRN
|.|| .  |||||.||||||| ..         .  ||.|.|||.|  |.|. |.. . |...   .  |   .... ||   ..|||  ..| ||.|  
larGvDddGnvanFVETEqIvyss........qycfsFtQvRGSiPiFWeqe.snsli.gpkiqitrsseatqsafdkHFdklfekYGd.vhivNLlktK

EkrrHEGVLHTQFLKNIEyLNQFLPNeeklCYISFDVARCNKAAnsmpSINVLNVMEDLSMKSILKNGWFQSfplsealkirpreafatldaHHSKDGRF
.   .|  |. .. | .. |.....      ...||  .  . .    . .... ...|  ...|  |.|.                       ...  .
s...sEieLseryekhlk.lsekpki....hlteFdfhketsqd....gfddvkkLlplieqdllefgyfsy....................dvkegkli

MIQHGICRTNCVDCLDRTNVAQFVIAKVALGCQLCAMGILDEPNLTlqsEVCRLLEDMFDEHGDTMALQYAGSQLVHSIKTYKKTAAFQERRRDVFQTLS
 .|.|..|||| ||||||||.|..|.| .|..|.  ... .. .     . .  |. .. ..||. . .| |.. . |  |.|..  .  . .|. .  |
seQdGVfRtNClDCLDRTNviQqliskrvlleqfrsikvisaidde...dflqklneLWadnGDaisqiYTGtgalkssftrkgkrsiagalsDatkSvs

RYYSNTFNDWDKQMAINLFLGVFRPRiTTMKNLWDLTSDYNLHFPYSL
|.|.| | |  || ||.|.|| .... . .. ...  .. ||.  .|.
RmyinnfvDkekQdaidllLgklpdq.eavelydpineyvnlrlrkse
subfamily_SAC1_pd Subfamily SAC1 88-578 7.6e-90 292.7 In-house 5-456 (458) alignment 
Range on Protein: 88-578
Range on HMM: 5-456/458.0
TNAFGILGCVRFVEGYYLIIITRAHAVATLGYHPVYKIVEVAMIPIAMDGVSTSS----EEQKYVKLFQSVDLSTDFYFSYSYDMSRTFQENSLRSDWN-
.. .||||... . | |||.||....|...  . .|.. .| .||..   .| ..    ||..|.|| ..|  |..||||| ||.....| ..  .  . 
vkiagilGiikLlsgkylivitkkeevgringkviyrvadveiipvkknslslteeqkkeekeylkllelvlksetfYfsytydltnslqrlekvtsaal

NHGQRRLEADERFVWNSFLLEPLRKNLISERWFVEIVHGYVRQEYIFLPIGRISLTIIGRRSTKYAGTRFLKRGANPTGNVANYVETEQIVWDMassgnv
.. .    |||||.||. ||| |||.   |.. . ...|..... . |   .|....| ||| . ||||. .||.. .|||||.|||||||         
kerslleradeRffwnkhlledlrkepelesfilPvikGfikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveae......

adGRFSSFVQMRGSVPMRWSQDPSTRgvvGKPLILIDNHEPHAQTAASHFRDVRNKYGNpIVIMNLIkrnEKRRHEGVLHTQFLKNIEYLnqflpNEEKL
    ..||||.|||.|. ||| |. .    || . . ..| . ..  .|. .  ..||.  |..||.   ... .|  |. .. . .. |     |..|.
..kaltsFvqvRGsiPllWsqkpnLk...ykPkvklsesedsldafkkhldeqielyge.nvlvnLv...dqkGsEkklgeayesvvral.....nkkki

CYISFDVAR-CNKaansMPSINVLNVMEDLSMkSILKNGWFQSfplsealkirpreafatldahHS--KdgRFMIQHGICRTNCVDCLDRTNVAQFVIAK
 |..||  . |.|    |    .  ... |.     . |.|.                      ..  |      |.|. ||||.|||||||| | ..|.
kyvafDFHkeCrk....mrwdrlklLidqlek.elsqegyflk.....................seekk..ivkeqkgvvRtnCiDcLDRtnvvqsllar

VALGCQLCAMGILD-EPNLTLQSEVCRLLEDMFDEHGDTMALQYAGSQLVHSIKTYKKTAAFQERRRDVFQTLSRYYSNTFNDWDKQMAINLFLGVFRPR
 .|  ||  .|.|  | .|. ..|. .   ... ...|... |||| .   .  | .   ...   ||. ...|||| | | |  .| .|.|||| .|..
evLqkqleslgvlateskledsaeletsfknlwadnadavsvqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLflgkyrve
subfamily_Synaptojanin_pd Subfamily Synaptojanin 88-579 5.2e-57 184.8 In-house 4-441 (754) alignment 
Range on Protein: 88-579
Range on HMM: 4-441/754.0
TNAFGILGCVRFVE----GYYLIIITRAHAVATLGYHPVYKIVEVAMIPIAMDgvstSSEEQKYVKlFQSVDLSTDFYFSYSYDMSRtfqENSLRSDWNN
..|.|.|| .|         .|...| .. |  .    ..|| .. ..... .    .|.|.....  . .  |  |||| | | ..   . .| .  ..
vdaygllGvlrlnagdetlsflvlvtgcksvGkisdaeifkitstelvslrse....asdedriie.lkkllasgtfyfsssadsas...rldlslsaqr

HGQRRLEaDERFVWNSFLLEPLRKNLI-SERWFVEIVHGYVRQEYIFLPIGRISLTIIGRRSTKYAGTRFLKRGANPTGNVANYVETEQIVwdmassgnV
. | . | |.||.||  |   |..  . ...|..... | |.   ..    ..  ..| | |.. |||||  ||.|  |||||.|||||..        .
rkqeese.dnrffWnrslhlhlqrfgvncddWllkvmcGsveirtvyagakqakaalisrlsceraGtrfnvrGvndeGnvanfveteqvi........l

ADGRFSSFVQMRGSVPMRWSQdPSTRgvVGKP-LILIDNHEPHAQTAASHFRDVRNKYGNpIVIMNLIkrnEKRRHEGVLHTQFLKNIEyLNQFlpnEEK
.| . .||||.|||||. |.| |  .  ||.  . |  . |  | .   |.. ....||. .||.||.    ..  | ||...| |. .  ...   ...
lddkvtsfvqirGsvPlfWeq.PGlq..vGshkvklsrgfeasaaafdrhleqlkeryGe.vvivnll...Gskegeevlskafkkhlk.aseh...akd

LCYISFDVARCNKAANSmpsinvlNVMEDLSMKSILKngWFQSFplsealkirprEAFATLDAHHSKdgrfmIQHGICRTNCVDCLDRTNVAQFVIAKVA
. ...||. .  |. ..       ...|.|  | . .  ...|.           . | . . . .|      |.|. |.||.|||||||  | |..   
vpfvkfdyhqkvkggkk.......eklekllkkqlkl..flesa...........sfflskgkevek.....eqtGvlrvnClDCldrtnavqtvlglev

LGCQLCAMGILDEPNltLQSEVCRLLEDMFDEHGDTMALQYAGSQLVHSiktYKKTAAFQERRRDVFQTLsryySNTFNDWDKQMAINLFL--GVFRPRI
|  || |...   ..  . |.. . ..... . || ..  |||.. ...     |.. ...  | | .|.     | | |  || ||.|.|   ... ..
lekqlealklsskes..vvsrfeevfkslWsknGdeiskiyaGtgaleg...kakvsklkdgarsvarti....qnnfldsskqeaidllllgntyveel
Syja_N SacI homology domain 90-392 3.9e-86 280.1 Pfam-A 1-311 (319) alignment 
Range on Protein: 90-392
Range on HMM: 1-311/319.0
AFGILGCVRFVEGYYLIIITRAHAVATLG-YHPVYKIVEVAMIPIAMDGVSTS----------SEEQKYVKLFQSVDLSTDFYFSYSYDMSRTFQENSLR
|.||||..|. ...||..||..  ||...  ||.||| .|..||.  .  ..|          .||.|..||..... |. |||||.||..|..|..| .
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSydyDltrslqrksek

SDWNNH-----GQRRLEADERFVWNSFLLEPLrKNL--ISERWFVEIVHGYVRQEYIFLP-IGRISLTIIGRRSTKYAGTRFLKRGANPTGNVANYVETE
.  ..       .   |.|||||||..||.|| ..|    .||.. ...|.| |. | .    ...||.| |||.|.||||.|.||..  |||||.||||
eeeekeeeskslpllkevderFvWNrnllkpl.ielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvEtE

QIVWDmassgN-VADGRFSSFVQMRGSVPMRWSQdPST-RgvvGKPLILID-NHEPHAQTAASHFRDVRNKYgNPIVIMNLIkrnEKRRHEGVLHTQFLK
|||..     .  ...|. ||||.|||||. |.| .|.      || | |. ..|.. .....||... ..| ..||..||.   ||. .|. |. .. .
qivse.....kkeeskrvfSfvqiRGSvPlfWeq.asnls...lkpkikitrsseasqkafkkHfkklikrY.gkivvvnLl...ekkgrEkkLseayee

NIEYLNQFLPNEEKLCYISFDVARC
 |..||..|....|| ||.||. . 
linklnkklkekkklkyiefDfhke
Syja_N SacI homology domain 90-392 3.9e-86 280.1 In-house 1-311 (319) alignment 
Range on Protein: 90-392
Range on HMM: 1-311/319.0
AFGILGCVRFVEGYYLIIITRAHAVATLG-YHPVYKIVEVAMIPIAMDGVSTS----------SEEQKYVKLFQSVDLSTDFYFSYSYDMSRTFQENSLR
|.||||..|. ...||..||..  ||...  ||.||| .|..||.  .  ..|          .||.|..||..... |. |||||.||..|..|..| .
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSydyDltrslqrksek

SDWNNH-----GQRRLEADERFVWNSFLLEPLrKNL--ISERWFVEIVHGYVRQEYIFLP-IGRISLTIIGRRSTKYAGTRFLKRGANPTGNVANYVETE
.  ..       .   |.|||||||..||.|| ..|    .||.. ...|.| |. | .    ...||.| |||.|.||||.|.||..  |||||.||||
eeeekeeeskslpllkevderFvWNrnllkpl.ielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvEtE

QIVWDmassgN-VADGRFSSFVQMRGSVPMRWSQdPST-RgvvGKPLILID-NHEPHAQTAASHFRDVRNKYgNPIVIMNLIkrnEKRRHEGVLHTQFLK
|||..     .  ...|. ||||.|||||. |.| .|.      || | |. ..|.. .....||... ..| ..||..||.   ||. .|. |. .. .
qivse.....kkeeskrvfSfvqiRGSvPlfWeq.asnls...lkpkikitrsseasqkafkkHfkklikrY.gkivvvnLl...ekkgrEkkLseayee

NIEYLNQFLPNEEKLCYISFDVARC
 |..||..|....|| ||.||. . 
linklnkklkekkklkyiefDfhke
subfamily_INPP5F_pd Subfamily INPP5F 150-574 3.5e-74 241.5 In-house 128-505 (951) alignment 
Range on Protein: 150-574
Range on HMM: 128-505/951.0
LFQSVDLSTDFYFSYSYDMSRTFQENSLRSDWNNHGQRrleaDERFVWNSFLLEPLRKNLISE--RWFVEIVHGYVRQEYIFLPIGRISLTIIGRRSTKY
  .    ...||.|...|...|.|...| .. .   .     ||||.||.|||..| ..  ..  .. . .. |.|  . |     ..|||.| |||.| 
elkkllsdgsFYysldfDltntlqkrgleeksestddw....derFfWNkfllkdlinyrdkldkefltpviqGfvetkeisieklkvsltlisrrSrkr

AGTRFLKRGANPTGNVANYVETEQIVwDMASsgnvadGrFSSFVQMRGSVPMRWSQDpstrGVVGKPLILIDNHEPHAQTA-ASHFRDVRNKYGNpIVIM
||||| .|| .  |||||.||||.|.  ...          ||.|.|||||. |.|.    |   || | |.. |  .| |   ||    .|||. .||.
agtrfkrrGidddgnvAnfvEtElil.svek......y.vlsftqirGSvPvfweqs....gkkykpkikitrseeetqpaFdehfkeqlkkygk.vviv

NLIKRnekRRHEGVLHTQFLKNIEYLNqflpnEEKLCYISFDVARCNKAANSMPSINVLNVMEDLSmksilkngwfqsfplsealkirpreA-FATLDAH
||..    . .|  | ... .... |.     .... .|.||  . ..  .. .  .... ... .                           .      
nllsq...kssekklskaykeqllkle.....skdvflikfdfheetsgekfenvsklieliknei.........................kevgyfsyd

HSKdGRFMIQHGICRTNCVDCLDRTNVAQFVIAKVALGCQLCAMGILDePNLTLQ-SEVCRLLEDMFDEHGDTMALQYAGSQLVHSIKTYKKTAAFQERR
 ..   .  |.|. ||||.||||||||.|  |.|..|  ||  .|... |. ... .|. . |.... ..||..  ||||.. . .  | |    .   .
vke.kviseqkgvfRtnclDcldrtNvvqqaiskavlelqleklglfe.pessiddeellqklkklWadngdaisrqYagtnalkgdltrkgerklaGvl

RDVFQTLSRYYSNTFNDWDKQMAINLFLGV
 |  ...|||| | | |  .| .|.| || 
kdgyksvsryylnnfkdkyrqkvidlllGk