Gene C45E5.1 in Caenorhabditis elegans

Synonym: CELE_K09H11.7, CELE_K09H11.7

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily PGP
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP036_AA protein Get Run
CeleP036_AA_15-286 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Chronophin_1 16-286 2.6e-48 155.7 In-house 2-241 (261) alignment 
Range on Protein: 16-286
Range on HMM: 2-241/261.0
DTFVFDADGVLWTGDIPIPGAAEWINTLlDDPEKSVFITTNNSTKTLEQYMKKVKKMRFGRLGRENLLSPTIVLCDYFKQnsdKFENQYIYLIGVENLKK
... .| ||||. |.  .||||| |..|  . .|.|...||||..| |.. ...|.. .  .  |...| ..    . .|   .  .  .|..| | |.|
qlvLlDldGVlikgeeavpgAaelieal.kqagkevlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaallrq...qaakakvyvlGeeglrk

SLEEGGGVKCFGTGPdhkdnytdgdfinevdvkskIPKAVVVSFDSHFSYPKLMKAANFLADPlVEFLVCNEDSTFPGPVpGmILPETGPWSAAIQNVSG
.|.| | .   .. .                     ..|||| .| ..|. || .|.. . |.   |.. |.| |.| .  | |.| ||   ||..  ||
elreaGlrlvdeped....................rveaVvvGydeelsfeklaeaialirdg.alfvatnrDptvPlee.G.iaPgtGslaaaveaAsg

RKPDIVfGKPHEQLANFLKSRVQAgkfNSERTVMFGDRLDTDMMFGKNNGFTTVWMQTGVNTLLDIELARK
|.| .| |||.  . .   ....|   ..|.||| |||||||. .|.. |..|. . ||| .| ... ..|
replvv.GKPepvmfeealekiga...dpeetvmvGDRldTDilagaraglstllvltGvseleeaqaykk
Hydrolase haloacid dehalogenase-like hydrolase 16-264 1.9e-11 36.1 Pfam-A 2-214 (215) alignment 
Range on Protein: 16-264
Range on HMM: 2-214/215.0
DTFVFDADGVLWTGDIPI--PGAAEWINTLLDD--------PEKSVFITTNNSTK-----------------------TLEQYMKKVKKMRF-GRLGREN
.|.||| .|.|..|  ..  .|........ .          .. |.....|||.                       . ...|... .  . ..|. ..
ktvvfDktGTLtegepsvallgnkaalalaaaletgsehpigkavvaaakanstrggltgfatfigrgvsgkvdgivlgnpewmtalglrviapdlvaae

L-LSPTIVLCDYfkqnsdkfenqyIyligvenlkksleegggvkcfgtgpdhkdnytdgdfinevdvkskipkAVVVSFDSHFS---YPKLMKAANFLAD
    ...|.  .            .                                                ....  . .|.   .|....| . | .
gqskgrtvvvva............v................................................qaralgviafadpvkpeaaeavasLke

PLV-EFLVC-------NEDSTFPGPvpgmilpeTGPWSAAIQNvsgrkpdivfGKPHEQLANFLKSRVQAgkfNSERTVMFGDRLdTDMMFGKNN
  .  .|.        . . ...|         .. .  |             |||...| . .  . |    . ....|.||.. .|. .... 
aGievvlltgdnpetaeaiakqagi........edslvfaevv..........gkPepklfvaaieeLqi...dpgevamvGDgv.nDapalaaA
subfamily_PGP_pd Subfamily PGP 17-296 1.3e-97 317.4 In-house 1-267 (279) alignment 
Range on Protein: 17-296
Range on HMM: 1-267/279.0
TFVFDADGVLWTGDIPIPGAAEWINTLLdDPEKSVFITTNNSTKTLEQYMKKVKKMRFGRLGRENLLSPTIVLCDYFKQnsDKFENQyIYLIGVENLKKS
|..||.|||||.|. .||||||..|.|  . .|.|...||||||. |...||.||..| .. .|..||......||.||  .|||.. .|..| |.||..
tvlfDcDGVlWlgetaipgaaealnaLk.klgKkvlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkq..kkfekk.vyvlgeeglkee

LEEGgGVKCFGTGPDHKDNYTDGDFINEVDVKSkIPKAVVVSFDSHFSYPKLMKAANFLADPLVEFLVCNEDSTFPGPVpGMILPETGPWSAAIQNVSGR
|.|  |....||||..... .|.||..|.....   .||||..|...||.||.||||.| .| |.||..|||...|..  ....|..|.. |||...|||
Lkea.giellgtgpeklkdeldedfveelkldk.dvgAVvvgvdeklsyakllkAanyLrepevlflatneDallplkk.evvipgaGslvaaieaasgr

KPdIVFGKPHEQLANFLKSRVQAgkfNSERTVMFGDRLDTDMMFGKNNGFTTVWMQTGVNTLLDIELARKNGesTKIPDF
|| .|.|||.|.|...|... .    . |||.|.||||.||..||||.|..|.....||..| |.| ..|..  ...||.
kp.lvlGKPnelllelllekeei...dpertlmiGDrlktDilfgkncGlqtLlvlsGvtkledveeikkee..klvPdy
Chronophin_2 18-285 3.7e-45 145.4 In-house 3-254 (282) alignment 
Range on Protein: 18-285
Range on HMM: 3-254/282.0
FVFDADGVLWTGDIPIPGAAEWINTLLDDpEKSVFITTNNSTKTLEQYMKKVKKMRFGRLGRENLLSPTIVLCDYFKQNSDKfeNQYIYLIGVENLKKSL
 .|| |||.| |.  ..||.| ...|     | |.. |||||.. |.|..|  .. |  .  |...| ..    |... .|   .  .. || | |.| |
vlfdcdgviwngekavagapevvsrlara.gknvlfvtnnstrarenyvlkfarlgfadvaaeqifssaycsaaylrdvadv..rgkvfviggeglrkel

EEGgGVKCFGTgPDHKDnytdgDFINEVDVKSKIpKAVVVSFDSHFSYPKLMKAANFLADPLVEFLVCNEDSTFPGpVPGMILPETGPWSAAIQNVSGRK
.|  ||.. .  .|...       | .. .. .. .||.| .| .... || ||. .| |.   .|  ..|   |    | |.| .|  .||..  ||||
rea.gvpvved.adeqe.....asiydcaldpdv.ravlvgydekltflklakacaylrdadclllatdrdpwhpl.sdgritpgsgsltaaletasgrk

PdIVFGKPHEQLANFLKSRVQagkFNSERTVMFGDRLDTDMMFGKNNGFTTVWMQTGVNTLLDIELAR
  .| ||| . . . . |  .    .  |..| ||||.||..||.| |..||   ||| .| . .  .
a.tvigkpsrfmfecissqfs...vdparslmigdrletdilfgsncglstvltltgvssleeaqeys
Hydrolase_6 Haloacid dehalogenase-like hydrolase 18-121 1.2e-23 74.4 Pfam-A 1-99 (101) alignment 
Range on Protein: 18-121
Range on HMM: 1-99/101.0
FVFDADGVLWTGDIPIPGAAEWINTLLDDpEKSVFITTNNSTKTLEQYMKKVKKMRFGrLGRENLLSPTIVLCDYFKQNSDkfeNQYIYLIGVENLKKSL
|.|| ||||| || .|||||| ...| .  .| |.. ||||.|. |.|.||..|. .  .  |.....  .. .|.|..     .. ...|| |.|.. |
flfDvdGvLwrgdkaipgaaealkalraa.gkpvvllTNnsskseeeyakkleklgvd.vteeqvvtsataaaeylkkrka...dkkvlvigeeglreel

EEGG
.| |
keaG
subfamily_LHPP_pd Subfamily LHPP 18-98 3.5e-08 24.7 In-house 1-79 (227) alignment 
Range on Protein: 18-98
Range on HMM: 1-79/227.0
FVFDADGVLWTGDIPIPGAAEWINTLLDdPEKSVFITTNNSTKTLEQYMKKVKKMRFGrLGRENLLSPTIVLCDYFKQNSD
.. |  |||...| .||||.| .. | .  .. | . ||.. .. .. ... ... |. .  |...... . ... .... 
vllDlsGvlhnedaaipgavealkrLrq.agvkvrfvtNttkeskralverLirlgfd.veeeeiftsleaarqllrerkl
subfamily_LHPP_pd Subfamily LHPP 143-275 2.1e-10 32.0 In-house 94-220 (227) alignment 
Range on Protein: 143-275
Range on HMM: 94-220/227.0
NEVDvKSKiPKAVVVS-FDSHFSYPKLMKAANFLADPLVEFLVCNEDSTFPGPVPGMILpETGPWSAAIQNVSGRKPDIVfGKPHeqlANFLKSRVQAGK
...|  .| |.|||..  . .|.| .| .| . |..   . |.. . . .     |..| . |.. .|..   | |  .| |||.   |.| .. ... .
edid.tdk.pnavviglapesfeyetlnqafrllleakkakliainkgkyykrkdGlal.gpGafvkaleyatgvkaevv.GKPs...alffekaleelg

FNSERTVMFGDRLDTDMMFGKNNGFTTVWMQTGV
 . |. || || .  |.    . |. .|  .||.
vdpeeavmiGDdvedDveGAlkaGlrgvlVktGk
Hydrolase_like HAD-hyrolase-like 222-280 5.9e-11 33.5 Pfam-A 2-57 (75) alignment 
Range on Protein: 222-280
Range on HMM: 2-57/75.0
FGKPHEQLANFLKSRVqagKFNSERTVMFGDRLDTDMMFGKNNGFTTVWMQTGVNTLLD
 |||....  .   .    . .....|| ||.|.||. ...| | ...   ||| .  |
lgKPnpgmydkalevl...gappsevvmiGDslatDieaAnnaGirsilVltGvsreed
PGP_phosphatase Mitochondrial PGP phosphatase 226-275 3.6e-07 19.8 Pfam-A 120-167 (168) alignment 
Range on Protein: 226-275
Range on HMM: 120-167/168.0
HEQLANFLKSRVQagKFNSERTVMFGDRLDTDMMFGKNNGFTTVWMQTGV
.|.. ...|.. .    ...  .. |||| ||..... .| . ||.. ||
aeevleyfkekkv..vtkadeiavvgDRllTdvlmanmmGslsvwlregv