Gene F30A10.6 in Caenorhabditis elegans

Synonym: CELE_F30A10.6, sac-1

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Sac
Subfamily SAC1
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP073_AA protein Get Run
CeleP073_AA_194-510 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_SAC1_pd Subfamily SAC1 57-516 6.7e-203 665.4 In-house 2-456 (458) alignment 
Range on Protein: 57-516
Range on HMM: 2-456/458.0
TDIKFIYGILGTIKLVSGYALIVITKASLIGQVNNHNIWTIQDAEIIPYKKTTLHLTEKQIRYNRLFTDMLTHVLSIGGFYYSTTLDISRTFQWLQENAV
.... |.||||.|||.||  ||||||.. .|..|...|....|.||||.||..|.|||.| . .. ....|..||.  .||.|.|.|.....|.|.... 
aevvkiagilGiikLlsgkylivitkkeevgringkviyrvadveiipvkknslslteeqkkeekeylkllelvlksetfYfsytydltnslqrlekvts

PLFKTRSMLDRASERFIWNGHLLSQIRQVPGAERYTLPVIHGFIGQNRVNVNGKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFVETEQIVEYTnpd
. .|.||.|.||.|||.||.|||...|..|..|...||||.||| ......|.||||...||||||.|||.|...|||| .|..|||||||||||..   
aalkerslleradeRffwnkhlledlrkepelesfilPvikGfikikelslnakeikfilisRRsifRaGtRyfvRGvdkeGnvanfvEtEqiveae...

KHLTSFVQLRGSIPLLWTQKPNLRWQPMPTLKPTDDQLAAFNRAFSWHKQHYgGKHVIVNLVNQKGREKKVGGELERISRQANIEFVRYHQFDFHKECHS
|.||||||.||||||||.|||||...|...|. ..|.|.||..........| |..|.||||.|||.|||.| ..|...|..| . ..|..|||||||..
kaltsFvqvRGsiPllWsqkpnLkykPkvklsesedsldafkkhldeqiely.genvlvnLvdqkGsEkklgeayesvvralnkkkikyvafDFHkeCrk

MQWHRIDLLREQLSQEISSFGYFYLSPNSMeTSRFQRGFFRTNCMDCLDRTNVVQSMLARESLTEQLRMLGILYSEQKVQDIPLLEDAFKQMWADNGDEC
|.|.|..|| .||..| |..|||. | ... ... |.|..||||.|||||||||||.||||.|..||..||.|..|.|..| . ||..||..||||.|..
mrwdrlklLidqlekelsqegyflkseekk.ivkeqkgvvRtnCiDcLDRtnvvqsllarevLqkqleslgvlateskledsaeletsfknlwadnadav

SRQYAGTGALKADFTRHGRRTYVGAMKDGVNAVSRYVRNNFGDGYRQDSIDLFLGNFLVD
| |||||||||.||||.|.||..||..||||.||||..||| ||.||||||||||...|.
svqYaGtgAlKtDftRtGkrtllGalrDgvnsvsryyknnfldgerqdsidLflgkyrve
Sac_COG5329 61-513 3.5e-133 436.9 In-house 60-519 (1070) alignment 
Range on Protein: 61-513
Range on HMM: 60-519/1070.0
FIYGILGTIKLVSGYALIVITKASLI-GQVNNHNIWTIQDAEIIPYKKTTLHLTEKQ---IRYNRL----FTDMLTHVLSIGGFYYSTTLDISRTFQWL-
 |||.|| |.|   . |||||..|   .......|  |.. ..|....      |     .... |        |. .|| | ||.||..||. |.|.  
eiygvlGlielegslflivitgkskvaqvipgetiykilavdfislnnnkwddeeiesdeasteklrsehpcselkkLlsngsFYfStdfditntLqkrl

---QENAVPLFKTRSMLDR-ASERFIWNGHLLSQIRQ-VPGAERYTLPVIHGFIGQNRVNVNGKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFVET
   .|  |. .... |  . . | .|.. . ||.. . .   ...  .||.||. .  ..|..| | ||.|||||..||| || .|||| ||..||||||
keelelsvdtadeefmwnsflleelinyrsklsslekqlldnagFlttvIrGFaetvfikvkkktiaLtlISRrSskragtRflarGvDddGnvanFVET

EQIVEYTnpdKHLTSFVQLRGSIPLLWTQ-KPNLRWQPMPTLKPTDDQLAAFNRAFSWHKQHYGGkHVIVNLVNQKGREKKVGGELERISRQANIEFVRY
||||.     .. .||.| |||||. |.|   .|  ..   ..      .||...|.   . ||.  .||||...|..|...  ..|.  .. . . . .
EqIvyss...qycfsFtQvRGSiPiFWeqesnsligpkiqitrsseatqsafdkHFdklfekYGd.vhivNLlktKssEieLseryekhlklsekpkihl

HQFDFHKECHSMQWHRIDLLREQLSQEISSFGYFYLSPNSMETSRFQRGFFRTNCMDCLDRTNVVQSMLARESLTEQLRMLGILYSEQKVqdiPLLEdAF
..||||||.  ...... .|.... |....||||  . .  ..  .| |.|||||.||||||||.|...... |.||.| ...  . ..    ..|. ..
teFdfhketsqdgfddvkkLlplieqdllefgyfsydvkegkliseQdGVfRtNClDCLDRTNviQqliskrvlleqfrsikvisaidde...dflq.kl

KQMWADNGDECSRQYAGTGALKADFTRHGRRTYVGAMKDGVNAVSRYVRNNFGDGYRQDSIDLFLGNF
...||||||  |..| |||||| .|||.|.|. .||..| .. |||.  ||| |. .||.|||.|| .
neLWadnGDaisqiYTGtgalkssftrkgkrsiagalsDatkSvsRmyinnfvDkekQdaidllLgkl
subfamily_FIG4_pd Subfamily FIG4 62-515 1.4e-95 311.8 In-house 70-543 (569) alignment 
Range on Protein: 62-515
Range on HMM: 70-543/569.0
IYGILGTIKLVSGYALIVITKASLIGQVNNHNIWTIQDAEIIPYKKTTLH--LTEKQIRYNRLFTDMLthvLSiGGFYYSTTLDISRTFQWLQE------
 ||||| .....|| ||..||.. .... .| |..|.| ..|. .... .   . .. || .|| |.    |.   ||.| . |..||.|          
ayGilGfvrflegyylilvtkrkkvaviGghaiykiedialikitedskksekssdearylklfkdvd...lt.knfyfsysydltrtlqtnlllsdsnr

---NAVPLFK--TRSMLDRASERFIWNGHLLSQIRQVPGAERYTLPVIHGFIGQNRVNVNGKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFVETEQ
   .|..  .    ..  .|.|.|.|| .||......   ... | .||||. |....| ||.|..|.|.||| . || || ||||. .|. || |||||
ekekaedrvditieakkldanekfvWnnflleplkdtvktfdWlleiihGfvsqskisvlgksiyvtliarrsskfaGarflkrGvnnkGdvaneveteq

IV----EYTNPDKHLTSFVQLRGSIPLLWTQKP-NLRWQPMPTLKPTDDQLAAFNRAFSWHKQHYGGKHVIVNLVNQKG---REKKVGGELERISRQAN-
||    | .  .....||||||||.|| |.|   .|  .|  ... .|  . |  . |.   |.||.  .|.||| .|    ||...  |.|.  .  | 
ivheasegsldsdryssfvqlrGsvPlyWsqdasklvtkPpikidvvdPfasaaalhfddlfqryGspiiilnlvkkkekrkresilleefeaaieylne

----IEFVRYHQFDFHKECHSMQWHRIDLLREQLSQEISSFGYFYLSPNsMETSRFQRGFFRTNCMDCLDRTNVVQSMLARESLTEQLRMLGILYSEQKV
     . ..| ..|...  .| . . .. | .  .. .   |.|. .|. .|... |.|  ||||.|||||||. | .... .|. ||  |||. . .  
flPeekklkyiswdmaraskskeenvlevlekyaeksvkktGiflsapd.lestkiqeGivrtnCvdcldrtnaaqfvigkvalgyqlkslGiideskle

QDIPLLeDAFKQMWADNGDECSRQYAGTGALKADFTRHGRRTYVGAMKDGVNAVSRYVRNNFGDGYRQDSIDLFLGNFLV
 |  .    ..... | ||  . ||.|.   .   | .  ...    .| .....||  | | |  .||.|.|||| .  
fdsdvv.rlleelyedlGdtlalqygGsqlvntiktyrkiaqwssksrdiletlkryysnsfvdadkqdainlflGvysp
Syja_N SacI homology domain 62-360 5e-89 289.6 Pfam-A 1-318 (319) alignment 
Range on Protein: 62-360
Range on HMM: 1-318/319.0
IYGILGTIKLVSGYALIVITKASLIGQVN-NHNIWTIQDAEIIPYKKTTLHLT------EKQIRYNRLFTDMLTHVLSIGGFYYSTTLDISRTFQWLQEN
.|||||.|.| |.. |.||||.. ..... .|.|..|.. |.|| .... . .      |.. . .. .  .|. .|| |.||.|.. |..|..|  .|.
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSydyDltrslqrksek

AVPLF----KTRSMLDRASERFIWNGHLLSQIRQVP-GAERYTLPVIHGFIGQNRVNVN-GKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFVETEQ
.        |. ..|... |||.|| .||... ..   ..|..||.|.||..|. ..|. .|...||.|||||..|||.|. .||.| ||..||||||||
eeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvEtEq

IVEY-TNPDKHLTSFVQLRGSIPLLWTQKPNLRWQPMPTLK-PTDDQLAAFNRAFSWHKQHYgGKHVIVNLVNQKGREKKVGGELERISRQA-----NIE
||.  ....|...||||.|||.||.|.|..|| ..| ....  .... .||.. |.  ...| || |.|||...||||||.. ..|.  ..      . .
ivsekkeeskrvfSfvqiRGSvPlfWeqasnlslkpkikitrsseasqkafkkHfkklikrY.gkivvvnLlekkgrEkkLseayeelinklnkklkekk

FVRYHQFDFHKECHSMQWH
 ..| .|||||||......
klkyiefDfhkeckgkkfe
Syja_N SacI homology domain 62-360 5e-89 289.6 In-house 1-318 (319) alignment 
Range on Protein: 62-360
Range on HMM: 1-318/319.0
IYGILGTIKLVSGYALIVITKASLIGQVN-NHNIWTIQDAEIIPYKKTTLHLT------EKQIRYNRLFTDMLTHVLSIGGFYYSTTLDISRTFQWLQEN
.|||||.|.| |.. |.||||.. ..... .|.|..|.. |.|| .... . .      |.. . .. .  .|. .|| |.||.|.. |..|..|  .|.
aygilGlirllsesyllvitkrekvakirgehpiykiksvefiplnseeeessaieeekeeeekeeekllkllkkllssgsfYfSydyDltrslqrksek

AVPLF----KTRSMLDRASERFIWNGHLLSQIRQVP-GAERYTLPVIHGFIGQNRVNVN-GKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFVETEQ
.        |. ..|... |||.|| .||... ..   ..|..||.|.||..|. ..|. .|...||.|||||..|||.|. .||.| ||..||||||||
eeeekeeeskslpllkevderFvWNrnllkplielkldlsrwllpliqGfveqrsievkskkkveltLIsRrsvkraGtRylrRGidddGnvANfvEtEq

IVEY-TNPDKHLTSFVQLRGSIPLLWTQKPNLRWQPMPTLK-PTDDQLAAFNRAFSWHKQHYgGKHVIVNLVNQKGREKKVGGELERISRQA-----NIE
||.  ....|...||||.|||.||.|.|..|| ..| ....  .... .||.. |.  ...| || |.|||...||||||.. ..|.  ..      . .
ivsekkeeskrvfSfvqiRGSvPlfWeqasnlslkpkikitrsseasqkafkkHfkklikrY.gkivvvnLlekkgrEkkLseayeelinklnkklkekk

FVRYHQFDFHKECHSMQWH
 ..| .|||||||......
klkyiefDfhkeckgkkfe
subfamily_Synaptojanin_pd Subfamily Synaptojanin 62-517 5.5e-88 287.2 In-house 6-440 (754) alignment 
Range on Protein: 62-517
Range on HMM: 6-440/754.0
IYGILGTIKLVSG----YALIVITKASLIGQVNNHNIWTIQDAEIIPYKKTTLHLtekqiryNRLFTdmLTHVLSIGGFYYSTTLDISRTFQwLQENAvp
.||.|| ..| .|      |...| .. .|.... .|. | . |... .... .        .|. .  | ..|. | ||.|.. | ..... |. .|  
aygllGvlrlnagdetlsflvlvtgcksvGkisdaeifkitstelvslrseasde.......driie..lkkllasgtfyfsssadsasrld.lslsa..

lfKTRSMLDRASERFIWNGHLLSQIRQVP-GAERYTLPVIHGFIGQNRVNVNGKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFVETEQIVEYtnpD
  . |.  .   .||.||  |  ....    .... |.|. | .    | .  |..| ..||| |  |||.||. |||. .|..||||||||..     |
..qrrkqeesednrffWnrslhlhlqrfgvncddWllkvmcGsveirtvyagakqakaalisrlsceraGtrfnvrGvndeGnvanfveteqvill...d

KHLTSFVQLRGSIPLLWTQkPNLR--WQPMPTLKPTDDQLAAFNRAFSWHKQHYGgKHVIVNLVNQKGREKKVGGELERISRQANI-EFVRYHQFDFHKE
...||||| |||.||.| | | |.   . .   .  . . |||.| ..  |..|| . |||||. .|. |. .  . ..  .. .  . | . .||.|..
dkvtsfvqirGsvPlfWeq.PGlqvGshkvklsrgfeasaaafdrhleqlkeryG.evvivnllGskegeevlskafkkhlkasehakdvpfvkfdyhqk

CHSMQWHRID-LLREQLSQEISSFGYFYLSPNsmETSRFQRGFFRTNCMDCLDRTNVVQSMLARESLTEQLRMLGilySEQKVQDIPLLEDAFKQMWADN
... . . .. ||..||.. ..|...|. . .  | .. | |  |.||.||||||| ||..|. | |..|| .|.    ..|.. .  .|..||..|  |
vkggkkeklekllkkqlklflesasfflskgk..evekeqtGvlrvnClDCldrtnavqtvlglevlekqlealk...lsskesvvsrfeevfkslWskn

GDECSRQYAGTGALKADftrhgrrTYVGAMKDGVNAVSRYVRNNFGDGYRQDSIDLFL-GNFLVDS
|||.|. |||||||...       . |. .|||  .|.| ..||| |. .|..|||.| || .|..
GdeiskiyaGtgalegk.......akvsklkdgarsvartiqnnfldsskqeaidllllgntyvee
subfamily_INPP5F_pd Subfamily INPP5F 65-514 4.1e-111 363.7 In-house 67-507 (951) alignment 
Range on Protein: 65-514
Range on HMM: 67-507/951.0
ILGTIKLVSGYALIVITKASLIGQVNNhNIWTIQDAEIIPY--KKTTLHLTEKQIRYNRLFtDMLTHVLSIGGFYYSTTLDISRTFQWLQENavplfKTR
. | |.|... . |.. ...   .||| . |.. | .  .|  .| . .  |..   .||  . | . || | ||||.. |...|.|  ...     .  
ctgliglielegkiivatiegkskvnn.kkwdlididssgylqlkeekeqneeeklekrll.eelkkllsdgsFYysldfDltntlqkrgle.....eks

SMLDRASERFIWNGHLLSQIRQVPGAE--RYTLPVIHGFIGQNRVNVNGKEIKLTIISRRSIYRAGVRFYKRGVDVDGHAANFVETEQIVeytNPDKHLT
...|   |||.|| .||... ..   .  ....||| ||.  . .... ....||.|||||  ||| ||..||.| ||. |||||||.|.   .  |.  
estddwderFfWNkfllkdlinyrdkldkefltpviqGfvetkeisieklkvsltlisrrSrkragtrfkrrGidddgnvAnfvEtElil...svekyvl

SFVQLRGSIPLLWTQKPNLRWQPMPTLKPTDDQLAAFNRAFSWHKQHYGGkHVIVNLVNQKGREKKVGGELERISRQANIEFVRYHQFDFHKECHSMQWH
||.| |||.|. |.|. ..  ...   . ...  .||.. |. . ..||   |||||..||..|||..   ..  .... . | . .||||.|.......
sftqirGSvPvfweqsgkkykpkikitrseeetqpaFdehfkeqlkkygk.vvivnllsqkssekklskaykeqllkleskdvflikfdfheetsgekfe

RIDLLREQLSQEISSFGYFYLSPNSmETSRFQRGFFRTNCMDCLDRTNVVQSMLARESLTEQLRMLGILYSEQKVQDiPLLEDAFKQMWADNGDECSRQY
 .. | |.. .|| ..|||    .  .    |.| |||||.||||||||||...... |  ||. ||.. .|....| . | ...|..||||||  ||||
nvsklielikneikevgyfsydvke.kviseqkgvfRtnclDcldrtNvvqqaiskavlelqleklglfepessidd.eellqklkklWadngdaisrqY

AGTGALKADFTRHGRRTYVGAMKDGVNAVSRYVRNNFGDGYRQDSIDLFLGNFL
||| ||| |.||.| |   |..|||.. ||||  ||| | |||. ||| ||.  
agtnalkgdltrkgerklaGvlkdgyksvsryylnnfkdkyrqkvidlllGklp