Synonym: CELE_F35C11.2, F35C11.2
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_PTPN6_pd | Subfamily PTPN6 | 43-173 | 6.2e-10 | 33.6 | In-house | 10-139 (306) | alignment | ||
Range on Protein: 43-173
Range on HMM: 10-139/306.0
EGKEEEVNKnvTPEEAFKAVTVEGPELLNQMHTSaMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK-DDFYNASWVDGYSK--KSAYIFAQAP
| ...|..| . |. || | | |.|.... .. . . .|. ||. |||.|| |. .. . .|. ||. ... .| . .|| .|
eqrvselek..eeeslekagfeeefeelqqeeak.kllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgc
FNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRK
... | ||||| . . .|.. |. | |
let.tvsdFWrmvwqensrvivmttkevErgkek
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 56-355 | 2.7e-42 | 140.5 | In-house | 15-274 (278) | alignment | ||
Range on Protein: 56-355
Range on HMM: 15-274/278.0
EEAFKAVTVEGPELLNQMHTsamtYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPfNDHTEYVFWRMVS
..|... .. | |..... .. .. ....|.|.||... ...||||| | . .| .|..|||.||||... ..| .|.| ...|.. |||||
llnlktllllefeellsfkl....dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgP.lpetvedFwrmvw
ERKPSMILVFGDIDEKQKRKapydisdrgfeksflhefgaksleecelkakiCRKFWPekGSKKDFPALSIQASDDHSETHMKTFNLTVT--EKKQDHQT
| . ..|.. . .|... | | ..|| |. . . ... . ... ......|.|| ... ..
elgvttivmLtelvelgrvk................................caqYwp..ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtv
VLMHFYEWADASKL--PEYMLDMRASIKLQYIrsS-KktgvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYS
. .|.. | | . .. .||. .. .. . . ||.. | || ... ........... |..| . |... ...||.|.. | |
thyhylgwpdhgvpeslsllldflkavreale..dsn......gpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyr
TACEMLM
.|.|.
flyeall
|
|||||||||
| subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 57-388 | 5.6e-246 | 808.9 | In-house | 1-332 (332) | alignment | ||
Range on Protein: 57-388
Range on HMM: 1-332/332.0
EAFKAVTVEGPELLNQMHTSAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEYVFWRMVSERK
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
eafkavtvegpellnqmhtsamtypntydkflnnmdmnriphlycfdhsrvelapqdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserk
PSMILVFGDIDEKQKRKAPYDISDRGFEKSFLHEFGAKSLEECELKAKICRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHF
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||
psmilvfgdidekqkrkapydisdrgfeksflhefgaksleecelkakicrkfwpekrskkdfpalsiqasddhsethmktfnltvtekkqdhqtvlmhf
YEWADASKLPEYMLDMRASIKLQYIRSSKKTGVCIGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
|||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||||||||
yewadasklpeymldmrasiklqyirsskktgvcigpimlvcatgvekcaisatidiivsriteehrvgfketmsaikmqrfgcfrtvgpystacemlmk
FAVTTGVVHDAAIGEKPKPQKSIVGKGPKSGF
||||||||||||||||||||||||||||||||
favttgvvhdaaigekpkpqksivgkgpksgf
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 68-174 | 7.7e-15 | 49.4 | In-house | 10-113 (290) | alignment | ||
Range on Protein: 68-174
Range on HMM: 10-113/290.0
ELLNQMHTSAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGkdDFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDID
|...... | .| . |. .| ..|| . .||||..| .| |. ||| |. | ||..| |. .| ||.|| |.| .... .
eiyldirkeasdfptreaklpenrnlnryrdvspydhsrikleradn..dyinaslveleeakrsyiltqGPlp.ntvdhfWqmvWeqkskavvmlnkvv
EKQKRKA
||.. |
ekeqikc
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 70-173 | 1.3e-08 | 29.3 | In-house | 19-123 (307) | alignment | ||
Range on Protein: 70-173
Range on HMM: 19-123/307.0
LNQMHTSAMTYPN--TYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKDDFYNASWVDGYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDID
.... | |. | . | | | || . | |..|. . . |. | .. | .| || | . | | || |. . | .... ..
vdefrvlakktpegvtveafsantdknryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgpl.entqysfwamaiqekvesvimlckvi
EKQKRK
| | |
elakik
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 71-356 | 2.8e-42 | 140.9 | In-house | 37-302 (307) | alignment | ||
Range on Protein: 71-356
Range on HMM: 37-302/307.0
NQMHTSAmTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK---DDFYNASWV--------DGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSM
..... .. .. ....|.|.||... ...||.|| | . ||. .|..|||.| ||| .| ..| .|.| .. | . ||||. | . ..
lsvtvfl.lgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe.tvedFwrmlweqgvtv
ILVFGDIDEkqkrkapydisdrgfeksflhefgaksleeceLKAKICRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVT---EKKQDHQTVLMHF
|. . .| |. ..| ..||..|... . . . . . . ... ..|.|| .... .. .|.
ivmltelve................................lgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhy
YEWADASKL--PEYMLDMRASIKLQYIRSSKKtgvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHR---VGFKETMSAIKMQRFGCFRTVGPYSTAC
..| | . .| .||. .. . ...|. ||.. | || .. ....... ... .|. | . |... ...|| |.. . . | .
tgwpdhgvppsfeelldfieevrkaleelpkg.....gpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrfly
EMLMK
|.|..
ealle
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 74-361 | 1.6e-44 | 147.8 | In-house | 12-277 (284) | alignment | ||
Range on Protein: 74-361
Range on HMM: 12-277/284.0
HTSAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK---DDFYNASWVDGY-----SKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGD
| .... .. ....|...|| ......||||| | . ||. .|..|||.|||| .| ..| .|.| .. | . ||||| | . ..| .. .
ltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpn.tvedFwrmvweqnvrvIVmlte
IDEKQKRKapydisdrgfeksflhefgaksleecelkakiCRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVTE---KKQDHQTVLMHFYEWADA
..|... | | ..||..|... . ... . . . ......|..| ... .. .|. .| |
lvengrek................................caqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdh
SKL--PEYMLDMRASIKLQYIRsskktGVCIGPIMLVCATGVEKCAIYATIDIIVSRITEEH---RVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
. || .|.. .. .. . . |||. | || . . ....|.. ... .|. .| . |... ...||.|.. |. | .|.|. .
gvppspedlleflrlvrellen.....lpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealley
AVTT
. ..
lklk
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 74-174 | 1.9e-20 | 67.6 | In-house | 31-133 (563) | alignment | ||
Range on Protein: 74-174
Range on HMM: 31-133/563.0
HTSAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK---DDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQ
.| ... . . . .| || . .|.|||.|.| || |. ||...||| |. |.| .| | .| | ||||. |.. ..| . .. |..
etiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkd.tfddFWrmiWeqnvaiivmitnlverg
KRKA
.||
rrkc
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 74-170 | 6.9e-11 | 36.5 | In-house | 24-119 (287) | alignment | ||
Range on Protein: 74-170
Range on HMM: 24-119/287.0
HTSAMTYPNTYDkfLNNMDMNRIPHLYCFDHSRVELA--PQDGKdDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVF-GDIDEKQ
..|..|. .. . | .. || .. .|..|| |. .. | |. || .| .| .. |.| ||.|. | |||.| |.. . ... ...| .
esstatfkaaee..laavkknryadvlPiddtrvllsaegelGs.dyinanyvasytddeafiaaqgPiaa.tvrdfwravletrsasvitmtreveear
|
|||||||||
| subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 74-137 | 7.3e-08 | 26.5 | In-house | 30-94 (95) | alignment | ||
Range on Protein: 74-137
Range on HMM: 30-94/95.0
HTSAMTYPN--TYDKFLNNMDMNRIPHLYCFDHSRVELAPQDgKDDFYNASWVDGYSKKSAYIFAQ
.. .|| | |. ||. .. .| .|| |. . |. || .||||..| .|| ||
ksismtsgapytvgsseanipknrflnifpydatrvvlttkr.dsdyinacfvdgyarkncyiaaq
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 75-176 | 1.9e-12 | 41.9 | In-house | 36-136 (297) | alignment | ||
Range on Protein: 75-176
Range on HMM: 36-136/297.0
TSAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKksAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKR
.|...|.| . |.. .| .| |||.|| . . |. |||.| |. . .| | | .. | ||.|| . ..|.|.. | .|..|.
peaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmka.tvadfWamvldeqvstivmlnddnerdkk
KAPY
| |
cary
|
|||||||||
| DSPc_SM00195 | 76-357 | 4.8e-58 | 191.9 | In-house | 12-261 (263) | alignment | |||
Range on Protein: 76-357
Range on HMM: 12-261/263.0
SAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDG--KDDFYNASWVDGYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKqkrk
|. . . | .. .|...|| . ...||.||.| .... ..|..||....|..||..||..|.|. ..| |||||.|.| ..|... . .|.
stspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl.pstvedFWrmvweekvkiivmlteeeen....
apydisdrgfeksflhefgaksleecelKAKICRKFWPEK-GSKKDFPALSIQASDDHS---ETHMKTFNLTVTEKKQDHQTVLMHFYEWADAsKLP---
. . | ..|||. |.|..| .|.. . .. |....|..|| ..|...... ... .| | ..|
............................gkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdh.gvpdst
EYMLDMRASIKLQYIRSskktgvcIGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
...|.. ..| .. .| |||. .| .||.......|||||.|...||..| ..|.......||.|...| |....|.....
ksvlellravkksksts.......sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
| PTPc_SM00194 | 76-357 | 4.8e-58 | 191.9 | In-house | 12-261 (263) | alignment | |||
Range on Protein: 76-357
Range on HMM: 12-261/263.0
SAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDG--KDDFYNASWVDGYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKqkrk
|. . . | .. .|...|| . ...||.||.| .... ..|..||....|..||..||..|.|. ..| |||||.|.| ..|... . .|.
stspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl.pstvedFWrmvweekvkiivmlteeeen....
apydisdrgfeksflhefgaksleecelKAKICRKFWPEK-GSKKDFPALSIQASDDHS---ETHMKTFNLTVTEKKQDHQTVLMHFYEWADAsKLP---
. . | ..|||. |.|..| .|.. . .. |....|..|| ..|...... ... .| | ..|
............................gkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdh.gvpdst
EYMLDMRASIKLQYIRSskktgvcIGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
...|.. ..| .. .| |||. .| .||.......|||||.|...||..| ..|.......||.|...| |....|.....
ksvlellravkksksts.......sgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 76-357 | 3.1e-42 | 140.4 | In-house | 42-288 (297) | alignment | ||
Range on Protein: 76-357
Range on HMM: 42-288/297.0
SAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK---DDFYNASWVDGYSK-KSAYIFAQAPfNDHTEYVFWRMVSERKPSMILVFGDIDEKQk
.. . .. .. .|.|.||... ...||||| | | || .|..|||.||||.. . ..| .|.| ...| . ||||| | . ..|. . .|..
lslkpdysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgP.lpetvedFwrmvweqgvtvivmLtklvelg.
rkapydisdrgfeksflhefgaksleecelkaKICRKFWPEKGSkkDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKL--PEYM
. | ..|||.|. . ... . . . ......|.|| ... .. .... | | . .|..
................................rkcaqywpeegg..tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslell
LDMRASIKLQYIRSSKKtgvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
|.. .. .. ...|. ||. | || ... ........... .|..| ..|... ...|| |.. | . | ...|...
leflelvrealaelpkg.....gpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallel
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 76-174 | 1.4e-13 | 45.4 | In-house | 26-125 (290) | alignment | ||
Range on Protein: 76-174
Range on HMM: 26-125/290.0
SAMTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRK
. .|... . .|. || . .|.||||| ..... |. ||... | ..| .|| ||.|. .| ||||. | . ..... . | .| |
aekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLp.ktlddfWrmiweknveivvmaCrevelgkkk
A
C
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 78-387 | 8.9e-46 | 152.0 | In-house | 31-304 (317) | alignment | ||
Range on Protein: 78-387
Range on HMM: 31-304/317.0
MTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDG--KDDFYNASWVDGYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKQKRKap
.. .. ....|.|.||.|. ...||||| | | .| .|..|||.|||...| ..| .|.| ..| . ||||| | . ..|. . . .|....|
kldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPl.pntvedFwrmvweqgvtvivmLteleelgrek..
ydisdrgfeksflhefgaksleecelkakiCRKFWPEkGSKKDFPALSIQASDDHSETHMKTFNLTVT--EKKQDHQTVLMHFYEWADASKL--PEYMLD
| ..||. |... . .... . . . ... ..|.|. .... .. .|. | | . |. .||
..............................caqYwpl.getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllld
MRASIKLQYirsS--KktgvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAvTTGVVHDAAI
. .. .. . . ||.. | || ... ........... .|..| ..|.. ...|| |.. | . | ...|... ..... |
fleavreal...edpg......gpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl.krkltlepas
GEKPKPQKSIVGKGPKSG
| |..| . . ...
elklkllklliplalddv
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 78-357 | 1.6e-44 | 147.9 | In-house | 37-285 (288) | alignment | ||
Range on Protein: 78-357
Range on HMM: 37-285/288.0
MTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDG--KDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKap
.... .. .. .|.. || ......||||| | . || .|..|||..||| .| ..| .|.| .. | . ||||| | . ..| .. ...|....|
pdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpn.tvedFWrmvweqnvrvIvmltklvelgrek..
ydisdrgfeksflhefgaksleecelkakiCRKFWPEkGSKKDFPALSIQASDDHSETHMKTFNLTVT------EKKQDHQTVLMHFYEWADASKL--PE
| ..||. |... . ... . ... ......|.|| ... .. .|.. | | . ||
..............................caqYwpl.ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspe
YMLDMRASIKLQYIrsskktgVCIGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
.||. .. .. . ||.. | || ... ....|...... .|..| . |.. ...||.|.. |. | .|.|. .
llldflrlvrkala.......sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 78-173 | 1.5e-15 | 52.0 | In-house | 39-135 (293) | alignment | ||
Range on Protein: 78-173
Range on HMM: 39-135/293.0
MTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQ--DGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRK
.. . .. | . || . .|||||.||. . ..|. ||....||. . .| .| |. . | ||||| |.| |.|... .. || | |
kdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpe.tvddfWrmvwekkssiivmltqlvekgkvk
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 78-168 | 3.8e-08 | 27.6 | In-house | 23-111 (285) | alignment | ||
Range on Protein: 78-168
Range on HMM: 23-111/285.0
MTYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDgkDDFYNASWVDGYSK-KSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDE
| || . | |.|| . | . .|| | .| |. |||. | .|.|| .| |. . | ||.|. . | . .|.. . |
mppnctytayeanpdlnryadvrcieetrvvlknhd..rdyihaswmrmpgkdqstyittqgplpe.tlsdfwhmiyqekiayvlmlctlfe
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 79-362 | 4.9e-48 | 159.3 | In-house | 28-281 (297) | alignment | ||
Range on Protein: 79-362
Range on HMM: 28-281/297.0
TYPNTYDKFLNNMDMNRIPHLYCFDHSRVELapQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKapydi
.. .. ....|...|| .. ...||.|| | .|...|..|||.||||. | ..| .|.| .. | . ||||| | . ..|... . .|... |
lgslsvallpenleknRykdilpydhtRVkl..ddegsdYinAsyvdgydlkrkfIatqgPlpn.tvedFWrmvweqnvtvIvmltelvelgrek.....
sdrgfeksflhefgaksleecelkakiCRKFWPEK-GSKKDFPALSIQASDDHS--ETHMKTFNLTVTE--KKQDHQTVLMHFYEWADASKL--PEYMLD
| ..||.. |. . . .... . .. ........|.|| ... .. .|. | | . |...||
...........................caqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslld
MRASIKLQYiRSSK-KtgvciGPIMLVCATGVEKCAIYATIDIIVSRIT---EEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAVTTG
. .. .. . . . ||.. | || ... ....|...... .|..| ..|.. ...||.|.. |.. | .|.|... ..
fielvrkvl.kllpsg.....gpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkl
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 79-356 | 3.6e-45 | 149.9 | In-house | 27-270 (273) | alignment | ||
Range on Protein: 79-356
Range on HMM: 27-270/273.0
TYPNTYDKFLNNMDMNRIPHLYCFDHSRVELapQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKapydi
.. .. .. .|.|.||.......||||| | .||..|..|||.|||| .| ..| .|.| .. | . ||||| | . ..| . ...|....|
lltysvallpenkdknrykdilpydhsrvkl..gdggsdyinAsyvdgynlkrkfiatqgPlpn.tvedfwrmvweqnvrviVmLtelvelgrek.....
sdrgfeksflhefgaksleecelkakiCRKFWPEKGS--KKDFPALSIQASDDHSETHMKTFNLTVTE--KKQDHQTVLMHFYEWADASKL--PEYMLDM
| ..||..| .. . ... . ... ......|..| .. .. .|...| | . .|..|..
...........................caqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllef
RASIKLQYIRSSKKtgvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
.. .. . .. ||.. | || . . ....|...... .|..| ..|.. ...||.|.. |. | .|.|..
ielvrkalealpsn.....gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 79-358 | 1.1e-43 | 145.1 | In-house | 57-299 (308) | alignment | ||
Range on Protein: 79-358
Range on HMM: 57-299/308.0
TYPNTYDKFLNNMDMNRIPHLYCFDHSRVELapqDGKDDFYNASWVDGY--SKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKapy
.. .. .. .|.|.|| .. ...||||| | |...|..|||.|||| .. ..| .|.| .. | . ||||| | . ..| .. ...|... |
lleysvallpenkdkNrykdilpydhsRVkl...degsdYInAsyvdgyssklprkfIatqgPlpn.tvedFwrmvweqnvrvIvmLtklvengrek...
disdrgfeksflhefgaksleecelkakiCRKFWPEK--GSKKDFPALSIQASDDHSETHMKTFNLTVTE--KKQDHQTVLMHFYEWADASKLP--EYML
| ..||.. |. . . ... . ... ......|..| ... .. .|. | | . | | .|
.............................caqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeill
DMRASIKLQYirsSKktgvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFA
|. .. .. .. |||. | || ... ....|...... .|..| . |.. ...|| |.. |. | ...|....
dflelvrksl...pg......gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleyl
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 79-338 | 1.7e-17 | 57.9 | In-house | 34-216 (392) | alignment | ||
Range on Protein: 79-338
Range on HMM: 34-216/392.0
TYPNTYDKFLNNMDMNRIPHLYCFDHSRVEL--APQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQkrkapy
||.| . |. || .| .|| | . ..|..|||..... . ||| .|.| . ||||| . ... | . ...| .
iypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaa.slddfwrmvfqenvttiamvtklkegd......
disdrgfeksflhefgaksleecelkakicrkfwpekgskkdfpalsiqasddhsethmktfnltvteKKQDHQTVLM-HFYEWADASkLPEYmldmrAS
| .|..|| || || |. .|.. .|
....................................................................kgddartvaqfhftewPdkd.vpkh.....ts
IKLQYIRS-SKKTGVCIGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRF
|..|. . . | |... |..|| . .. .|| .|.. . . | . .. |. .|
sllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrp
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 79-173 | 5.6e-15 | 50.0 | In-house | 35-132 (290) | alignment | ||
Range on Protein: 79-173
Range on HMM: 35-132/290.0
TYPNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKDD----FYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRK
. |.. .| || .. | |. | | |. | . ||....||..| .|| .|.| . .| ||... ..| ..|.. .| |..| |
ehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvs.ntlvdFWkliwqekvtiivmltniieegkvk
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 79-202 | 1.1e-12 | 42.4 | In-house | 33-154 (315) | alignment | ||
Range on Protein: 79-202
Range on HMM: 33-154/315.0
TYPNTYDKFLNNMDMNRIPHLYCFDHSRVEL--APQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKAPY
.|... . .|. || .|..|| | .. ..|..||| . .. . ||| .|.| . . ||||| . |.. | . . .| | |
iyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlka.svddfwrmvlqekvttivmvtkkqegdkikcrq
DISDRgfeKSFLHEFGAKSLEECELK
|| |. . |||. ..| .|.
ywPdr...kadsvefGsikvellsle
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 79-173 | 2.8e-11 | 37.2 | In-house | 32-127 (515) | alignment | ||
Range on Protein: 79-173
Range on HMM: 32-127/515.0
TYPNTYDKFLNNMDMNRIPHLYCFDHSRVEL--APQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQKRK
||.| . | || .| .|| | .. . |..||| . .. ||| .|.| . .. |||.| . ... | . . | | |
iypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvd.dfWrlvlqenvttiamvtklkegdkik
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 81-356 | 9.7e-41 | 135.4 | In-house | 2-244 (249) | alignment | ||
Range on Protein: 81-356
Range on HMM: 2-244/249.0
PNTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDG--KDDFYNASWVDGYSKKSAYIFAQAPfNDHTEYVFWRMVSERKPSMILVFGDIDEKQKRKapydi
. .. ....|.|.||.|. ...||||| | . .| .|..|||..||| | ..| .|.| ..| . ||||. | . ..|. . . .|... |
eysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgP.lpetvedfwrmlwelgitvivmLtslvelgrek.....
sdrgfeksflhefgaksleecelkakiCRKFWPEkGSKKDFPALSIQASDDHSETHMKTFNLTVT--EKKQDHQTVLMHFYEWAdASKLPEYMLDMRASI
| ..||. |. . . .... . ... ......|..| ....... .... | ..|... |. . |
...........................caqywpl.ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwp.dhgvppsfedlldfi
KLQYIRSSKK-TGvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
.. .. .| ||.. | || ............... .|..| ..|... ...||.|.. . . | .|.|..
eavrkaleelpkg...gpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 81-355 | 3.4e-28 | 94.2 | In-house | 24-269 (278) | alignment | ||
Range on Protein: 81-355
Range on HMM: 24-269/278.0
PNTYDKFLNNMDMNRIPHLYCFDHSRVElapqdgkdDFYNASWVDGYskKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQkrkapydisd
|. .|.|.|.||... ...||||| |. |||..||| . ..| .|.|.. .| ||||. | . . |. . |..
eitpalylgnldknRykdilpydhsrVk........dYINAsyidgy..pkkfIatqgPlp.stvadfwrmlwelgitvivmltelvelg..........
rgfeksflhefgaksleecelkAKICRKFWPEkGSKKDFPALSIQASDDHSETHMKTFNLTVT------EKKQDHQTVLMHFYEWADASKLPEY----ML
. | ..||| |. . . ... . . .. . |.|| | . . .|.. | | . .. .|
......................rekcaqywpe.ggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksfl
DMRASIKLQYIRSSKK---------TGvciGPIMLVCATGVEKCAIYATIDIIVSRIteEHRVGFKETMSAIKMQRFG-CFRTVGPYSTACEMLM
.. |. . . .. | ||. | || . .. .... ... |..| . |. . ...|| | .. . . | .|.|.
ellefirealkllaslllsslllldsg...gpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefll
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 82-342 | 3.1e-30 | 100.6 | In-house | 53-275 (319) | alignment | ||
Range on Protein: 82-342
Range on HMM: 53-275/319.0
NTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGdidekqkrkapydis
|. .| | ||| .. ||...| | . .|.. |. |||.|.|| .| || || | | | ||||. | . | |...
qtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPl.dntladfWrmiweyncstivllt...............
drgfeksflhefgaksleecelkAKICRKFWPEKGSKK-DFPALSIQASDDHSETHMKTFNLTVTEKKQDHQT-VLMHFYEWADASkLPEYMLDMRASIK
. | ..|| |. .| . ..... .. .| .. ..|. |..| . || | | |.| |. .|
.......................kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvG.vpdypsdlmrlvk
L-QYIrSSKKTGVciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFR
... ||. . .|.. |..|| . .| ..|....|. ||..| ... .. || .
kvrhl.tskenhr..anivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvq
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 82-342 | 1e-15 | 53.7 | In-house | 39-258 (314) | alignment | ||
Range on Protein: 82-342
Range on HMM: 39-258/314.0
NTYDKFLNnMDMNRIPHLYCFDhSRVELAPQDGKD-DFYNASWVDGYskkSAYIFAQAPfNDHTEYVF----------WRMV--SERKPSMILV------
..|.||| .|.|| .. ...| .|| | ..... |..|||.|||. ..| .|.| ...| . | |||| ..... .|
lvadlfln.rdknryldilpad.nrvilpglpvsgsdyinasyvdgf...lkfIatqgp.leitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevl
---------------FGDIDEKQkrkapydisdrgfekSFLHEFGAKSLEecelkakiCRKFWPEKGSKKDFPALSIQASDdH---SETHMKTFNLTVTE
. ..|... ..... . |. . ..||. .. . | | .| . .. ... | . |
adelsrLdaAlgKtpllildgng...............neptaadlellk........eelydpelferlgikylripvpD.gsaplledfdeflefiee
KkQdhqtvlmhfyewadasklpeymldmrasiklqyirsskktgvCIGPIMLVCATGVEKCAIYATIDIIVSRIteehRVGFKETMSAIKMQRFgCFR
. ||. |. |. . .......... .| ..|... ....|. .
a.d..........................................kggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRp.inp
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 82-174 | 6.5e-10 | 33.4 | In-house | 25-117 (283) | alignment | ||
Range on Protein: 82-174
Range on HMM: 25-117/283.0
NTYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGkdDFYNASWVD---GYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
. . .| .|| .. | |||| .. |. ||... | .. || ||.|. |.| ||.|| ..| . |... . | .. |
adiasadenkrknrnqeivpadqwrvelksesr..dyinavfipvsksykqdkkyiiaqsPl.drtvvdfWkmvfdekitaivmltklqedlrikC
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 83-344 | 4.5e-30 | 100.1 | In-house | 18-241 (284) | alignment | ||
Range on Protein: 83-344
Range on HMM: 18-241/284.0
TYDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGdidekqkrkapydisd
|. .| | ||| |. ||...| | . .|.. |. |||.. || .| || .| | | | ||||. | . | |...
tfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPl.dntladfWrmiweyncstivllt................
rgfeksflhefgaksleecelkAKICRKFWPEKGSKK-DFPALSIQASDDHSETHMKTFNLTVTEKKQDHQT-VLMHFYEWADASkLPEYMLDMRASIKL
. | ..|| |. .| . ..... .. .| .. ..|. |..| .. .|| | | |.| |. . .|
......................kdkcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvg.vpdypsdlmrlvkk
QYIRSSKKTGVciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTV
.||. . .|.. |..|| . .| ..|....|. ||..| ... .. || . .
vrhltskenhr..anivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdl
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 83-175 | 1.5e-15 | 52.0 | In-house | 42-135 (315) | alignment | ||
Range on Protein: 83-175
Range on HMM: 42-135/315.0
TYDKFLNNMDMNRIPHLYCFDHSRVEL--APQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKAP
| .| . || . .|.|||.| .| . |. ||...|||.|| || ||.| . |||.| | . . |... .. |..||||
dvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnva.svkdfwrlvfeedigkivmltnlvegekrkae
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 83-347 | 5.5e-13 | 43.6 | In-house | 36-260 (288) | alignment | ||
Range on Protein: 83-347
Range on HMM: 36-260/288.0
TYDKFLNNMDMNRIPHLYCFDHSRVELApqdGKDDFYNASWVDG-YSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKQKRKA-PYDISD
. |.|..| .| .|.. | .|| | ||| |. | | | ||||. . | ..|.|. | |... .. || |.|. | |
iidsfianptrdryenlprcditrvkls...ddpdfyiaanvvssakykrrlicaqaPl.ngtieelWkmllesdveyivmlcellekGkeksaeyfPsk
RGFEKSFLHEfgaksleecelkakicrkfwpekgskkdfpALSIQASDDHSETHMKTFNLTVTEKKQDHQ-TVLMHFYEWADASkLPE-YMLDMRAsikL
| . . . .. . . . .| | .... .... .|. || | . .|| |. .| |
lGekarigrl..............................ctvvkkkradidklvkvsllriskegeekvivkilhlleWdddg.vPenylsplrl...l
QYIRSSKKtgvcigPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPY
. ..| .| ||.. . .|| ... . | |.. . . .| .. .. . .|| . .| |
evlkslqk......PivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqy
|
|||||||||
| subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 83-162 | 2.6e-11 | 37.7 | In-house | 40-113 (303) | alignment | ||
Range on Protein: 83-162
Range on HMM: 40-113/303.0
TYDKFLNNMDMNRIPHLYCFDHSRVELApqdgKDDFYNASWVDGYSKKSAyIFAQAPFNdHTEYVFWRMVSERKPSMILV
. ..|..||| ||. . |.|||.|.|. . ||... |.| | |..| |.. || ||.|. |.| .|.
sknqfvknmdknrfvdvicldhskvkls....dssyihasyleldsskka.iltqlpls.htaadfwqmiieqkvkcvll
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 83-172 | 6.7e-11 | 36.3 | In-house | 45-134 (310) | alignment | ||
Range on Protein: 83-172
Range on HMM: 45-134/310.0
TYDKFLNNMDMNRIPHLYCFDHSRVELAPQDG-KDDFYNASWVDGYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKQKR
||. . ..| || . | | ||| | . .|. | .| .|..| .| |. .|| ||||. . . ||.. . |. .
tyeaykkymhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqgpl.qhtiidfwrmifqeraesilllckvgeegrp
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 84-355 | 2.8e-39 | 130.4 | In-house | 3-240 (245) | alignment | ||
Range on Protein: 84-355
Range on HMM: 3-240/245.0
YDKFLNNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKapydisdr
. ....|.|.||... ...||.|| | | .| .|..|||.|||| . .| .|.| .. | ||||. | . ..|. . . .|... |
vallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpe.tvedfwrmlwelgittivmLteeeelgrvk........
gfeksflhefgaksleecelkakiCRKFWPEkGSKKDFPALSIQASDDHSETHMKTFNLTVT--EKKQDHQTVLMHFYEWADASKL--PEYMLDMRASIK
| ..||. |... . .... . ... ......|.|| ... .. . .|.. | | . .|..||. ..
........................caqywpl.gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvr
LQYIRSSKktgvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLM
.. ..|. ||.. | || .. ........... .|..| . |.. ...|| |.. | . | |.|.
kalaedsn......gpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeall
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 84-174 | 3.3e-17 | 57.5 | In-house | 36-127 (297) | alignment | ||
Range on Protein: 84-174
Range on HMM: 36-127/297.0
YDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
. | |. || . |.|..|| || .|... |. ||..|||| .| |.| .| |.. .| ||||| |.. .|.. . |....|
asklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplk.ktvsdfWrmvWeqevlvivmttrvvergrlkc
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 84-174 | 4.9e-17 | 57.0 | In-house | 40-131 (305) | alignment | ||
Range on Protein: 84-174
Range on HMM: 40-131/305.0
YDKFLNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
.| .| || . .|..|. |.... .| |. |||.||||..| .|| ||.|... | |||.. | |.| |. . .. | .| |
vgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkn.tvadfWrliveekvstivmltklveggkdkC
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 84-162 | 1.7e-08 | 28.2 | In-house | 45-123 (302) | alignment | ||
Range on Protein: 84-162
Range on HMM: 45-123/302.0
YDKFLNNMDMNRIPHLYCFDHSRVELapQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEY--VFWRMVSERKPSMILV
| .|...|. ... . |. .| | . .|...||| |. . . | || | | .. ||||| ..| .. .
Ckafkknlkknqsedvpildsnlvkl..eaepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvi
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 86-355 | 3.7e-25 | 84.3 | In-house | 6-239 (243) | alignment | ||
Range on Protein: 86-355
Range on HMM: 6-239/243.0
KFLNNMDMNRIPHLYCFDHSRVELapqDGkDDFYNASWVDGYSKksaYIFAQAPFNDhTEYV----FWRMVSERKPSMILVFGDIDEKQKRkapydisdr
....|.. || .. ...||||| | .| .|..||...... . .| |.| .. | ||||. | . ..|. . . .|...
llpenlsknrysdilpydhsrvkl...eg.sdyinanliyvtpr...liatqgPlpe.tveddlasfwrmlwelgitvivmltelvElgre.........
gfeksflhefgaksleecelkakICRKFWPekGSKkDFPALSIQASDDHSETHMKTFNLTVTE---KKQDHQTVLMHFYEWADASKLP-EYMLDMRASIK
| ..|| |.. . .... . .. ... ..|... ... .. . |.. | | . . | ..
.......................kcaqywp..gev.tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldev
LQYIRS-----SKKTGvciGPIMLVCATGVEKCAIYATIDIIVSRIteehRVGFKETMSAIKMQRFG-CFRTVGPYSTACEMLM
..|.. ..| ||. . | || . . ....... ... .|.. |.. ...||.| .. | . | |.|.
refieellsllaldsg...gpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeall
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 86-174 | 1.1e-19 | 65.5 | In-house | 44-133 (564) | alignment | ||
Range on Protein: 86-174
Range on HMM: 44-133/564.0
KFLNNMDMNRIPHLYCFDHSRVELAPQDG--KDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
. | || . .||||| | . .| . |. |||..||| |. ||| .|.| .. | ||||| |.. |.| . ||.| |
nkpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlae.tiedFWRmvweqnsstiVmltkleEkgkvkc
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 86-175 | 2.7e-17 | 58.0 | In-house | 52-142 (298) | alignment | ||
Range on Protein: 86-175
Range on HMM: 52-142/298.0
KFLNNMDMNRIPHLYCFDHSRVELAP--QDGKDDFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAP
. .| . || . . .|.||| | .| . |. |||....|....|.| .|||.. .| |||||.|.. . | .. .. |..| | .
rkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPlt.etvedFWrmvteedigtiVmltnleeldktkyh
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 86-173 | 6.2e-10 | 33.5 | In-house | 37-125 (280) | alignment | ||
Range on Protein: 86-173
Range on HMM: 37-125/280.0
KFLNNMDMNRIPHLYCFDHSRVELApqDGKDDFYNASWVD----GYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRK
. .|.. || . .|. ||.| ... |. ||..|. . . || .| |.. .| ||.|| |.| |.|... .. |. . |
rkpenlsknryrdilpydatrvklk..esetdyinanyvnmeipstglvnryiatqGPla.ktatdfWqmvweqksslivmlttlverGrvk
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 86-195 | 4.6e-08 | 27.1 | In-house | 39-146 (312) | alignment | ||
Range on Protein: 86-195
Range on HMM: 39-146/312.0
KFLNNMDMNRIPHLYCFDHSRVELApqdGKDDFY-NASWVDGYSKKSAYIFAQAPFNDHTEYvFWRMV-SERKPSMILVFGDIDEKQKRKAPYDISDRGF
||. |.|| | . |.| | || | ..|| | .| .| .. .|.|... . . ||... | |.||. | ... .. | | ||
aflkfkdlnrypniqcwdrgrftla...gdenfyihanfvkictkperfvctqgplentcth.fwqlalslgstsiillcgfvedgsekcakyisdivgf
EKSFLHEFGAKS
. | ...
vdledhrvytey
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 86-171 | 2e-06 | 22.3 | In-house | 33-116 (273) | alignment | ||
Range on Protein: 86-171
Range on HMM: 33-116/273.0
KFLNNMDMNRIPHLYCFDHSRVELAPQDGkddFYNASWVDGYSK--KSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQK
| .|.| || .. .|..||.| . | . |||.. . || .| |. . .. ||.|| |.| ..| . ||.|
kkkenkdknryrnvlPydetrvklgdegg...yinaslikvpvgkdeyeyiacqGPlPetvk.dfwqmvweqkaeviamvtlekekgk
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 87-165 | 1.9e-15 | 51.8 | In-house | 38-117 (281) | alignment | ||
Range on Protein: 87-165
Range on HMM: 38-117/281.0
FLNNMDMNRIPHLYCFDHSRVELAPQ--DGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGD
.|. || . .|..||...|. . . |. ||..|.||... .|| .|.| . . . ||.|| |.| |.| .
adenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPa.slvafWqmvweqkvsaivmvtr
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 87-173 | 4e-11 | 37.4 | In-house | 17-105 (270) | alignment | ||
Range on Protein: 87-173
Range on HMM: 17-105/270.0
FLNNMDMNRIPHLYCFDHSRVELAPQ--DGKDDFYNASWVDGYSK-KSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKQKRK
. .. .|| . ..|| |.. | . ..|| .| |... | .|| |..| . | ||||. |.| . |.. .. || ..|
aargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPl.pttlksfwrmiweekvtaivmttgleEkgrkk
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 88-174 | 7e-19 | 62.9 | In-house | 56-143 (330) | alignment | ||
Range on Protein: 88-174
Range on HMM: 56-143/330.0
LNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
.|.. ||.... .|.||| |....|.. |. |||..||| .| .| || | . .| ||||. |.| . |... ...|... |
eenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPke.etvedfwrmiweqksativmltelkerkeekc
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 88-174 | 3.7e-18 | 60.7 | In-house | 47-133 (307) | alignment | ||
Range on Protein: 88-174
Range on HMM: 47-133/307.0
LNNMdMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
|.. || ... ||. || |.. ||. |. |||.. || .| .| ||.| . | ||||..| . .| . ...||...|
enal.knRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPv.eatigDfWRmiaeqevtlivmlsnlteknrkkc
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 88-173 | 7.3e-17 | 56.4 | In-house | 46-132 (319) | alignment | ||
Range on Protein: 88-173
Range on HMM: 46-132/319.0
LNNMDMNRIPHLYCFDHSRVELAPQDGKD--DFYNASWVDGYSKKSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQKRK
.| . || . . .|..|| |.. ||.. |. |||..||| .....| .||| .. .| ||||| |.. |.... .. || | |
eenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentie.dfWrmvWeeessivvmltklveklkvk
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 88-176 | 1e-15 | 52.7 | In-house | 7-96 (250) | alignment | ||
Range on Protein: 88-176
Range on HMM: 7-96/250.0
LNNMDMNRIPHLYCFDHSRVELAPQD--GKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQKRKAPY
..| . || .. .|.||| | ... . |. |||...||....|.| .|.|... .| ||||| |.| . |... .. |..| |
pqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatie.dfWrmvleeksgtivmLtnLkesektyhqy
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 88-173 | 1.1e-14 | 49.1 | In-house | 41-127 (314) | alignment | ||
Range on Protein: 88-173
Range on HMM: 41-127/314.0
LNNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRK
.| . ||. .. .|.||| | . || |. ||...|.| . .|.| .| | .. | . |||.| . . . |.. .. |... |
denreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqe.tvkdfWrlvydencasivmltelvevgrvk
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 88-170 | 1.3e-13 | 45.3 | In-house | 40-123 (296) | alignment | ||
Range on Protein: 88-170
Range on HMM: 40-123/296.0
LNNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQ
..|.. || .. .|. || | ||. .|. ||..||.. || .|| .|| .. . |||.| ... | . | . . .
kenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvd.efWrlvydeeisavvvLtktfdfa
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 88-173 | 4.2e-13 | 44.0 | In-house | 45-131 (288) | alignment | ||
Range on Protein: 88-173
Range on HMM: 45-131/288.0
LNNMDMNRIPHLYCFDHSRVELAP--QDGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQKRK
.| . || . .|. ||.| . . |. |||..||. || .|| .|.| | . ||..| |.| | |. . .. |..|.|
avnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvn.dfWelvyenktstivmltelveggktk
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 88-175 | 2.3e-12 | 41.5 | In-house | 47-136 (300) | alignment | ||
Range on Protein: 88-175
Range on HMM: 47-136/300.0
LNNMDMNRIPHLYCFDHSRVELAPQ-DGKDDFYNASWVDG--YSKKSAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAP
.| . ||.... ....||||.|. . .... ||| . .|. || ||.| ..| ||.|| | . ..|. .. |. | |.
penaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPl.eltvqdfWqmvWeqgvqlivmlteeeedgkeksf
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 88-174 | 1e-09 | 32.9 | In-house | 26-115 (274) | alignment | ||
Range on Protein: 88-174
Range on HMM: 26-115/274.0
LNNMDMNRIPHLYCFDHSRVELAPQDGKDD---FYNASWVDGYSKK-SAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
. || . ..||| | .....|. . || .. ||... ||. .| |. .| ||||. ... ..|.. .. |....|
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlp.ntvadfWrmiyqeevqvivmltklkeaneqkC
|
|||||||||
| subfamily_egg_pd | Subfamily egg | 88-215 | 1.3e-09 | 32.2 | In-house | 38-132 (307) | alignment | ||
Range on Protein: 88-215
Range on HMM: 38-132/307.0
LNNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKqkrkapydisdrgfek
||.. | ... | | |||.| . |. ||| | |.| .| ||||. . | ||||| . . |... |
dnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkn.tvddfwrmvfqeevqyivmltsrkes................
sflhefgaksleecelkaKICRKFWPEKGS
. | .|| |
..................erceyywpkaes
|
|||||||||
| subfamily_eak_pd | Subfamily eak | 88-357 | 3.4e-09 | 30.6 | In-house | 50-304 (332) | alignment | ||
Range on Protein: 88-357
Range on HMM: 50-304/332.0
LNNMDMNrIPHLYCFDHSRVELAPQ-DGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTeYVFWRMVSERK-PSMILVFGDIDEKQKRKAPYdISDRGFEK
|.... | . .. .|. |.|.. .. . ||| .. ||.. .. .|. ..||.|| |.| |... . |...| .. | |.. |.
leavnrn.vvkivpydrylvrltssqlnrlGyinaslaefsevGrkyiltGiasedkv.fafwqmvleqkspaivqlledvelkleksdky.fpdktree
sflHEFGAKSLEecelkakiCRKFwPEKGsKKDFPALSIQ-ASDDHSETHMKTFNLTvtEKKQDHQTVLMHFYEWADASKLPeYMLDMRASIKLQYIRSS
.|| .| ...| ... . .. | .. . | | | | | | . .. ... . .. |.... ...
...lkfGildve........rkef.vkrn.iletrllelskGnethrvlhykvfGwt..ettlpkyedflalrkvmkevGvl.llivmksallsstlkky
KKTGVCIGPIMlVCATGVEKCAIYATIDIIVSRITEEHRVG--FKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
..| . ||. .|.| .. .. ||... | . . .. . .| .| . . .| |.....
ihtppsfapii.qsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldy
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 88-183 | 3.6e-09 | 30.7 | In-house | 54-151 (297) | alignment | ||
Range on Protein: 88-183
Range on HMM: 54-151/297.0
LNNMDMNRIPHLYCFDHSRVELAPQ--DGKDDFYNASWV-DGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDRGF
.|.. || .. .|||||.| . . |.|. ||| . | ...||| .|.| . .| ||.|| |. .|. . ..|.. .. | |
eknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgpla.stvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGs
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 89-355 | 1.2e-17 | 58.5 | In-house | 39-290 (301) | alignment | ||
Range on Protein: 89-355
Range on HMM: 39-290/301.0
NNMDMNRIPHLYCFDHSRVELAPQDG----KDDFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDRGFE
.| .|| . .|. |. |.|. . .. |||..||||.| ..| ||.|.. .| |||.. . ||. |.. . .|..| |. .. |
enkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmk.ktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseae
KSFLHEFGAKSLEECELKAKICRKFW--PEKGSKkdfpalsiqasddhsE-THMKtfNLTVTEKKQDHQTVLMHFYEWADASKLPEYMLDMRaSIKLQYI
.. .| . .|. . . |.. ..||. . .. .. |...|. .. . .. .| . ..|. .. .| . .
seefgpftvtlvneqvyPdfvirqlnvkiqdgsn...............ngyier..kfkvksdksswdvlqlqvtdWpqdGvvreprtvLq.viddvih
RSSKKTGvciGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLM
| | | ||.. | .| . .| ...| . | | . |.. .. | | |.. ...
rqqkigg...gpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvid
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 89-173 | 2.9e-15 | 51.0 | In-house | 46-127 (287) | alignment | ||
Range on Protein: 89-173
Range on HMM: 46-127/287.0
NNMDMNRIPHLYCFDHSRVELApqDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRK
.| | ||. .. | || | . ..|. ||...|||..| |.| |..| . | ||... .|... |.. . |.....
qnkdknRltqilvpdnyrvllk..gehpdyinavfidgykekkafiiaesPmfn.tarnfWkliddrnvtaivmlcqekendeev
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 89-182 | 3.4e-15 | 51.0 | In-house | 47-141 (325) | alignment | ||
Range on Protein: 89-182
Range on HMM: 47-141/325.0
NNMDMNRIPHLYCFDHSRVELA--PQDGKDDFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDRG
.|.. || . . .|.||| | .|.. |..|||.. . || .. |||| .| .||.| . . |...| .|....| | | . |
enkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPlt.atindlWrlvldWrcsvvvvlneldlgkdrcavywpkemg
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 89-163 | 7.7e-11 | 36.5 | In-house | 32-103 (267) | alignment | ||
Range on Protein: 89-163
Range on HMM: 32-103/267.0
NNMDMNRIPHLYCFDHSRVELapQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVF
.| ..||. . .|..|| | .. .... |||.|.|| .| |.| | |.. | |. .. ..| ..| .
knqernrlddnlpyddtrvil..rtkeeeyinasyvegyktknafivtqdplkn.titdfltvihdqkvpvivll
|
|||||||||
| subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 89-170 | 1.4e-09 | 31.9 | In-house | 95-175 (244) | alignment | ||
Range on Protein: 89-170
Range on HMM: 95-175/244.0
NNMDMNRIPHLYCFDHSRVELAPQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQ
|| || || .|| |. . . |||.| . . ||..| |. | | ||.|. ||. ...|.| ..|..
nnswknregaglpfdfnrvplskgsmgntyinasfvgclgrtaeyiltqhplad.tsmdfwkmmlerhvnvlvvlgsveeed
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 89-174 | 1.5e-07 | 25.4 | In-house | 53-136 (290) | alignment | ||
Range on Protein: 89-174
Range on HMM: 53-136/290.0
NN--MDMNRIPHLYCFDHSRVELApqDG-KDDFYNASWVDGYskKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
.| . || . | | .|| | || . |. | .|.| |. .|..| . .| | .|||| . | ..| .. .. |. | |
kntefkknrykdvvcndktrvilk..dGydGdyvhanyvkGl..kamfiltqGalkd.tvidiwrmvlqekvaaivmlceliedGkakc
|
|||||||||
| subfamily_ptpA1_pd | Subfamily ptpA1 | 89-170 | 3.7e-06 | 20.9 | In-house | 46-127 (418) | alignment | ||
Range on Protein: 89-170
Range on HMM: 46-127/418.0
NNMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKsAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQ
| || . .|.||.| . | |. || ..|| | .| .| |. . | ||||| | . .|... |.
hntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypk.qfictqgplpn.tiadfwrmvwenrcriivmlsresenc
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 90-175 | 1.4e-20 | 69.1 | Pfam-A | 1-85 (235) | alignment | ||
Range on Protein: 90-175
Range on HMM: 1-85/235.0
NMDMNRIPHLYCFDHSRVELAPQDGKDDFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAP
|.. || .. ..|..||.| ..|. |..||..|.||..|...| .|.| . .| ||||| ..| ..| . . .||...| .
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlk.stiedFWrmvwqekvkvivmltsleekgrekca
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 90-175 | 1.4e-20 | 69.1 | In-house | 1-85 (235) | alignment | ||
Range on Protein: 90-175
Range on HMM: 1-85/235.0
NMDMNRIPHLYCFDHSRVELAPQDGKDDFYNASWVDGYSKKSAYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAP
|.. || .. ..|..||.| ..|. |..||..|.||..|...| .|.| . .| ||||| ..| ..| . . .||...| .
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlk.stiedFWrmvwqekvkvivmltsleekgrekca
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 90-174 | 1.3e-17 | 58.8 | In-house | 46-131 (318) | alignment | ||
Range on Protein: 90-174
Range on HMM: 46-131/318.0
NMDMNRIPHLYCFDHSRVELAPQDGK--DDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKA
| || . .||.||.| ...|. |. ||...||| .| ||| |||| . | ||||| |.. ..|... .. |. |.|
nkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpe.tieDfWrmvWeqnsavivmltqeeergkakv
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 90-347 | 4.6e-13 | 44.6 | In-house | 1-160 (182) | alignment | ||
Range on Protein: 90-347
Range on HMM: 1-160/182.0
NMDMNRIPHLYCFDHSRvelapqdgKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGdidekqkrKAPYDIsdrgfeksflh
|.| || .. ...|||| |. ||....|. . . .| .|.| .. | . |.||. |.. ..|. .|.
nldknrysdilpydhsr........dldyInanlylgslpatrfiatqgplls.tvadflrmlkelgittivnlt........eelywp...........
efgaksleecelkakicrkfwpekgskkdfpalsiqasddhsethmktfnltvteKKQDHQTVLMHFYEWADASKLPeymldmrASIKLQYIRSSKKtgv
.. .. . ... | | . . .. |..|. ..
.......................................................ellerlgiqylylpwpDhgvpd.......ldelldfieevle...
CIGPIMLVCATGVEKCAIYATIDIIVSRiteehRVGFKETMSAIKMQRFGCFRTVGPY
||. | || . . .. .... .. .|.. |... ....|.|.. | |
eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvitpnqy
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 90-173 | 6.2e-12 | 39.9 | In-house | 43-124 (288) | alignment | ||
Range on Protein: 90-173
Range on HMM: 43-124/288.0
NMDMNRIPHLYCFDHSRVELApqDGKDDFYNASWVDGYSKKS-AYIFAQAPFNdHTEYVFWRMVSERKPSMILVFGDIDEKQKRK
. . || . .||.|| | ..|||. |||.| . | . .| .||| . | ||.|| |.| |.| . . .|..| |
yseknrsrdilPyDhnRvklr..gskDDYinAsfvkdlspgcPdfiatqaPlq.stlnDFWlmvyeqkssviVmllskeelgkpk
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 90-173 | 3.3e-07 | 24.7 | In-house | 8-94 (239) | alignment | ||
Range on Protein: 90-173
Range on HMM: 8-94/239.0
NMDMNRIPHLYCFDHSRVELA--PQDGKDDFYNASWVDGYSK-KSAYIFAQAPFNDHTeYVFWRMVS-ERKPSMILVFGDIDEKQKRK
| || . .||||| | .| . |. |||.. | ||| .| . . ||||. ||. .... | |. ..|.
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveiss.gdfwrmmwqerrcvivmltglieghkkkc
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 90-173 | 3.5e-07 | 24.6 | In-house | 7-93 (239) | alignment | ||
Range on Protein: 90-173
Range on HMM: 7-93/239.0
NMDMNRIPHLYCFDHSRVELA--PQDGKDDFYNASWVDGYSK-KSAYIFAQAPFNDHTeYVFWRMVS-ERKPSMILVFGDIDEKQKRK
| || . .||||| | .| . |. |||.. | ||| .| . . ||||. ||. .... | |. ..|.
nkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveiss.gdfwrmmwqerrcvivmltglieghkkkc
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 91-173 | 2e-09 | 32.0 | In-house | 4-86 (237) | alignment | ||
Range on Protein: 91-173
Range on HMM: 4-86/237.0
MDMNRIPHLYCFDHSRVELAPQDGKDDFYNASWVDGYSK-KSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQKRK
|| . ..||||| | .. |. ||....|. || || |.. . ||.|| . | |.|... . |... |
kiknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscd.dfwqmvwqekcsvivmltgliegnelk
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 91-195 | 6.6e-07 | 23.4 | In-house | 51-153 (301) | alignment | ||
Range on Protein: 91-195
Range on HMM: 51-153/301.0
MDMNRIPHLYCFDHSRVELApQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDRGFEKSFLHE
| .| |.. | .. ||. .||| | |.. . .| .|.|... | . || |. . | ..| ||...| . .. . || .
kdkhryptvPckPstavevi.vdGkrvPihanwiptsGhphrfiatqgPlkn.tsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigr
FGAKS
| |
fkiki
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 92-171 | 5.8e-12 | 39.8 | In-house | 50-130 (439) | alignment | ||
Range on Protein: 92-171
Range on HMM: 50-130/439.0
DMNRIPHLYCFDHSRVEL--APQDGKDDFYNASWVDGYSKKSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQK
|| . |||.|| | | . ..|| ...|| .. || .|.| .. |. |||.| |.| . |... .. | |
tknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettd.dfwrlviekktvtivmltnlvesyk
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 93-318 | 8.8e-07 | 22.9 | In-house | 50-289 (350) | alignment | ||
Range on Protein: 93-318
Range on HMM: 50-289/350.0
MNRIPHLYCFDHSRVELA----PQDGK------DDFYNASWVDGY----SKKSAY--IFAQAPFNDhTEYVFWRMVSERKPSMILVFGDIDEKQKRKAPY
|| . ..||||.| . |.| .|. ||... . .. . | .||| | |.... . | .|| . .| . .|
knrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlps.tvddfykvillnkvkvilsltsdvelnlekcyr
DISDRGFEKSFLHEfgaKSLEECELKAKICRKFwpEKGSKKDFPaLSIQASDDHSETHMKTfNLTVTEKKQDHQTVL-MHFYEWADASKL--PEYMLDM-
. .... .. .| | .. . .. . ||... |||. . .. . .| | |. ... | | | | || .| .
YWqegsydditvkl...askwenimgindssly..sadvkkeas.dndnisddndlkdnns.ltaitlaasdPyvvyqlqvknWkDlslllnPesilqal
--RASIKLQYIRSSKKTGVCIGPIMLVCATGVEKCAIYATIDIIVSRI
. . . . | ||. |. || . .. |.| ..| .
evkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdf
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 109-176 | 1.9e-08 | 28.3 | In-house | 49-117 (319) | alignment | ||
Range on Protein: 109-176
Range on HMM: 49-117/319.0
LAPQDGKDDFYNASWVDGYSK-KSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQ-KRKAPY
..| || . .||.| || . .. || ||.. .| . |||.| |.. .|. |. |. |. | |
rigdddkdeyldasyvrGyddapnsyiaaqvsledsss.dfwrtvweqqsrvivqltdlselGikvcaey
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 114-345 | 1.2e-09 | 33.6 | In-house | 3-148 (172) | alignment | ||
Range on Protein: 114-345
Range on HMM: 3-148/172.0
GKDDFYNASWVDGYSKKSAYIFAQAPfNDHTEYVFWRMVSERKPSMILVFGDIdekqkrkapydisdrgfeksflhefgaksleecelkakicrkfwpek
. .|..|||..|.| . .| |.| ..| ||||. |.. ..|. .
egsdyinasyldlyyipdrfiatqgp.lrntladfwrmlkelgithivnltel...............................................
gskkdfpalsiqasddhsethmktfnlTVTEKKQDHQTVLMHFYEWADASK-LPEYMLDMRASIKLQYIRSSKktgvciGPIMLVCATGVEKCAIYATID
... .. .. . ... | | . |.|..|.. |. ...|.. ||. | || . . ..
...........................lydpellerlgiqylylpwpDhgvpllellleflefidellalspg......gpvlVHCsaGvgRtgtlvaay
IIVsriteeHRVGFKETMSAIKMQRFGCFRTVG
.. ... . |... ....|.|.. . .
lml......lglsleeavalvrekRpgavqnps
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 116-357 | 1.7e-09 | 33.2 | In-house | 4-224 (272) | alignment | ||
Range on Protein: 116-357
Range on HMM: 4-224/272.0
DDFYNASWVDGYSK---KSAYIFAQAPFNDhTEYVFWRMvSERKPSMILVFGDIDEKQKRKAPYDISdrgfeksflhefgaksleecelkakicrkfwpe
.. .||..|.|| . . ... ...| . |. |||. | . ..|. . . .|... | .. .
sgyiNardvggygrvvkpgrlyrsggplpl.taadfwrl.kelgiktivdLrseeErgrlkcdrywp.................................
kgskkDFPALSIQASDDHSETHM-------------------KTFNLTVT-EKKQDHQTVLMHFYEWADASKLPEYMLDMRASIKLqyirsskktgvcIG
.. | . ||. .|. .. || . .. .. ..|.. | | . .|..|.. . . |
.....girylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld............gg
PIMLVCATGVEKCAIYATIDIIVSRITEEHRVG--------FKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
|.. |. |. .... ..... ....| | |... .. || | . | . | .| |...
pvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallel
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 116-342 | 3.8e-08 | 28.7 | In-house | 2-154 (174) | alignment | ||
Range on Protein: 116-342
Range on HMM: 2-154/174.0
DDFYNASWVDGYSKKSAYIFAQAPFNdhteyvFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDrgfeksflhefgaksleecelkakicrkfwpekgs
.|..|||..|.. . .| |.|.. ||.|. | . .... . . |... | . ..
sdyinaspldlsyitprliagqgpla......fwemlkelgittvvmlleekelglykcinywpe...................................
kkdfpalsiqasddhsethmktfnltvTEKKQDHQTVLMHFYEWADASKLPEYMLDMRASIKLQYIRSskktgVCIGPIMLVCATGVEKCAIYATIDIIV
. . . . ... | | . . .|. .. ... . ||. | || .. . ....
...........................lredlerlgiqylylpwpDhgvpdlsillefvkfveealse.....dpggpvlVHCsaGvgRtGtlvaaylml
SRITeEHRVGFKETMSAIKMQRFGCFR
.. | | ... ....|| |..
rgll.eslvdaldlvrelRlqrpgmvq
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 119-345 | 1e-06 | 24.2 | In-house | 15-160 (176) | alignment | ||
Range on Protein: 119-345
Range on HMM: 15-160/176.0
YNASWVDGYskksAYIFAQAPFnDHTEYVFWRMVSERKPSMILVFGDIDEKQKRKAPYDISDrgFEKSFLhefgaksleecelkakicrkfwpekgskkd
||....|. ..| |.| .| . |..|. | . .... . . |... | |.. .. .|| .
inanlilgs....rpiatqgpl.prtladflemlkelgitavvnlteevelgrlkcpnywpe..leklgi..............................
fpalsiqasddhsethmktfnltvtekkqdhqtvLMHFYEWADASKLPEYMLDMRASIKLQYIRSSkktgvciGPIMLVCATGVEKCAIYATIDIIVSri
... | | . . |. . ..... ||. | |. . .. .... .
..................................qylhlpwpDhgvpdlelllellefirealkeg.......gpvlVHCsaGigRtgtlvaayllel..
teEHRVGFKETMSAIKMQRF-GCFRTVG
|. . |... ...||. |.. | .
..ekglsveealalvreqRplgavqtpe
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 124-345 | 2.1e-07 | 26.3 | In-house | 2-137 (152) | alignment | ||
Range on Protein: 124-345
Range on HMM: 2-137/152.0
VDGYSKKSAYIFAQAPFNDHTEyVFWRMVSERKPSMILVFGDIDEKQKRKAPYDIsdrgfeksflhefgaksleecelkakicrkfwpekgskkdfpals
.||| .. ..| .|.| . ... ||||. | . . |.. . .|. | | .. |
idgyampfefiatqgpgpntla.dfwrmlkelgittivmltellelgklkceqyi.............................................
iqasddhsethmktfnltvtekkqdhqtvLMHFYEWADASKLPEYMLDMRASIKLQYIRSSKKtgvciGPIMLVCATGVEKCAIYATIDIIVsriteeHR
... | | . . .| . . . .. .. .|. ||. | || . .. .... ..
.............................qylhlpwpDhgvpdlsqlllflllfieklaldkg.....gpvlVHCsaGvgRtgtlvaaylml......lg
VGFKETMSAIKMQRFGCFRTVG
| ..|... ....| | . . |
vsleeavalvrekRpgavpnpg
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 129-316 | 5.2e-07 | 24.0 | In-house | 33-173 (255) | alignment | ||
Range on Protein: 129-316
Range on HMM: 33-173/255.0
KKSAYIFaqapfndhTEYVFWRMVSERKPSMILVFGDIDEkqkrkapydisdrgfeksflhefgaksleecELKAKICRKFWPEKGSKKDFPALSIQASD
.|. |.. | |.... |.. . ...| | | . | . | || |. . ... ...
rknlysl........tvdkfyqtivqtktevvvmlcdfae...............................egvekcssyfplekdeklkladvnvtttk
DHSETHMKTFNLTVTEK-KQDHQTVLMHFYEWADASKLPEYMLDMRASIKLqyIRSSKktgvcigPIMLVCATGVEKCAIYATIDIIVS
.. ..| ..| | |. .|| ..|. . . || ... .|. .| || .....|.||. ..| .. ....
ssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareilnilkv..vrdsk.......svvvhCstGiGrsaafvlaelvyq
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 197-357 | 1.5e-14 | 48.7 | In-house | 131-296 (306) | alignment | ||
Range on Protein: 197-357
Range on HMM: 131-296/306.0
EECELKAKICRKFWPEKGSKKDFPALSIQASDDHSETH--MKTFNLTV-TEKKQDHQTVLMHFYEWADAS--KLPEYMLDMRASIKLQYIRSSKKtgvCI
.| | . | ..||.. .|... .|.. ...| .. ....... ..||. .. . .|| .| |.. | |. .||. .. .. .....
kevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleea...ea
GPIMLVCATGVEKCAIYATIDIIVSRITEE---HRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
|||. |. |. . . |||... |... . .... .. || | .| | ... |.
gpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikky
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 197-358 | 1.9e-10 | 35.4 | In-house | 123-288 (325) | alignment | ||
Range on Protein: 197-358
Range on HMM: 123-288/325.0
EECELKAKICRKFWPEK-GSKKDFPAL--SIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWAD--ASKLPEYMLDMRASIKLQYIRSSKKtGVCI
.| .|. . | ..||.. | | | .| .... .. |. .. ... ..| . ... | | | | .. . .| | . .
neldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtan.tkas
GPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFA
.||.. |..|| .. ..... .. .. || || . . .. .| .|| |. | |...
tpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveay
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 198-357 | 1.8e-11 | 38.6 | In-house | 120-277 (287) | alignment | ||
Range on Protein: 198-357
Range on HMM: 120-277/287.0
ECELKAKICRKFWPEKGSkKDFPALSIQASDDH--SETHMKTFNLTVTEKKQDHQTVL-MHFYEWADASKLPEYMLDMRaSIKlQYIRSSKKTGVciGPI
| | . ..| ..|||. | . .|. ... .. ....... ..|..|.|.| .. .| . |..|. . |. . ... .| | ..|
ekendeevcyqyWpeeks.vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtill.vie.emyktqrkrgn..tsi
MLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
. |. .| . |.. ... . . .| . . . ..|. | .|| | .......
vvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivley
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 198-322 | 1e-08 | 29.5 | In-house | 117-238 (290) | alignment | ||
Range on Protein: 198-322
Range on HMM: 117-238/290.0
ECELKAKICRKFWPEKGSKKD-FPALSIQASDDHSET-HMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLDMRASIKLqyIRSSKKtgVCIGPIM
| ||. | |...|||.| .. | ..... .... . . |.|. .|. .. .|. .| | |. . .. . |.| .|. .. |..
evelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhg.vPssakslleliel..vrelqe..sedaPlv
LVCATGVEKCAIYATIDIIVSRITEEH
. |. || . . .||.. . . .|.
vhCsaGvGrtGtiiaidyvrellkaek
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 198-351 | 1.3e-06 | 22.8 | In-house | 104-252 (290) | alignment | ||
Range on Protein: 198-351
Range on HMM: 104-252/290.0
ECELKAK-ICRKFWPEK-GSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYE-WADaSKLPEYMLDMRASIklQYIRsSKKTgvcigPI
... . . | |. ||. | . | |... . | ..| .|.|. .. . || . .. | . .. .| . . . | |... .|| |.
ksantslfaCakYvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnk.lnvqedtktllsli..qkvk.askt.....pv
MLVCATGVEKCAIYATIDIIVSRIT-EEHRVGFKETMSAIKMQRFGCFRTVGPYSTAC
.. | |. . |. |.|.. | .. | ... ..|.. || .. . .. .
ivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvd
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 199-357 | 2.5e-13 | 44.6 | In-house | 126-282 (290) | alignment | ||
Range on Protein: 199-357
Range on HMM: 126-282/290.0
CELKAKICRKFWPEKGSKKdFPALSIQASDDHSETHMKTFNLTVTEKK--QDHQTVL-MHFYEWADASKLPEYMLDMrASIKlQYIRSSKKTGvcIGPIM
| . . |...||....|. . ||. ..... ... . .| |..|. ...|.| .. | . |.... . .|. . .. .|.| ..|.
ieegkvkCqqYWpdsdtka.ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtil.lvie.emyktqrkrg..ntsiv
LVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
. | .| . |.. .... . . | . . . ..|. | || | . ......
vHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlty
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 199-335 | 4.7e-12 | 40.3 | In-house | 118-257 (288) | alignment | ||
Range on Protein: 199-335
Range on HMM: 118-257/288.0
CELKAKICRKFWPE-KGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTV--LMHFYEWAD--ASKLPEYMLDMRASIKLQYIRSSKKTGVcigP
||. . . ..||| || . |..||. .. .. .. .|... ...|. .... .|.. . . || .|.. .. .| .|. . |
eelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrkskt...P
IMLVCATGVEKCAIYATIDIIVSRITEEHrvGFKETM---SAIKM
... | .||.. ..| . .| ..... | ... | ..
lvvhCsaGvgRtgvfalvyaavrelekgn..glldiiqvvsrlre
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 200-355 | 6.6e-18 | 60.3 | Pfam-A | 78-234 (235) | alignment | ||
Range on Protein: 200-355
Range on HMM: 78-234/235.0
ELKAKICRKFWP-EKGSKKDFPALSIQAS----DDHSETHMKTFNLTVTEKKQ-DHQTVLMHFYEWADASkLPEYMLDMRasiklQYIRSSKKTG-VCIG
| . . | ..|| |.. .. . .... .|..|. .....|. ..... ... .|. .| | . .|| .. ..||. .|. . |
ekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhg.vpespksll.....dlirkvekskeaksg
PIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLM
|.. .| .||.........||.......|. | ..... .. ||.|.. .. | .....
pvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 200-355 | 6.6e-18 | 60.3 | In-house | 78-234 (235) | alignment | ||
Range on Protein: 200-355
Range on HMM: 78-234/235.0
ELKAKICRKFWP-EKGSKKDFPALSIQAS----DDHSETHMKTFNLTVTEKKQ-DHQTVLMHFYEWADASkLPEYMLDMRasiklQYIRSSKKTG-VCIG
| . . | ..|| |.. .. . .... .|..|. .....|. ..... ... .|. .| | . .|| .. ..||. .|. . |
ekgrekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhg.vpespksll.....dlirkvekskeaksg
PIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLM
|.. .| .||.........||.......|. | ..... .. ||.|.. .. | .....
pvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 200-357 | 4e-17 | 57.4 | In-house | 135-289 (298) | alignment | ||
Range on Protein: 200-357
Range on HMM: 135-289/298.0
ELKAKICRKFWPEKG-SKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKlPEY---MLDMRASIKLqYIRSSKKtgvciGPIM
||. . |.||..| . . .|......... ....... ..... .. . .|| .|.| . ||. .||... .. . . ... |..
eldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgv.penatsvldllrkvra.sqqqagn.....kpvi
LVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
. |. ||.. . || .. |. .|. | ... .....| | .| |. |. ...
vqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlea
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 200-343 | 9.4e-16 | 52.5 | In-house | 127-266 (564) | alignment | ||
Range on Protein: 200-343
Range on HMM: 127-266/564.0
ELKAKICRKFWPEKGsKKDFPALSIQASDD--HSETHMKTFNLTVTEKKQDHQTVLMHFYEWADAS--KLPEYMLDMRASIKLQYiRsskktgVCIGPIM
| . . | |.||||| .. . | .. .. .. ...||.|. ..... .. || .| | . .. .||.. .. . |||.
EkgkvkchkYWPekg.tetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.e......pdagPiv
LVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRT
| ||. .. .||... ||.||. | ....|.. || |
VhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqt
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 200-348 | 6.2e-13 | 43.5 | In-house | 127-274 (297) | alignment | ||
Range on Protein: 200-348
Range on HMM: 127-274/297.0
ELKAKICRKFWPEKGSKKdFPALSIQASDD--HSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKLPeymlDMRASIKLQYIRSSKK--TGVCIGPIM
. . | |...|..||... | .|.. . . .....| . |. . .| || | . .|| |..| .| .. ||..
nerdkkcaryWsdkgvtt.fGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaver....kdsassllklisevrkdfsqnaegPll
LVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYS
. | .|| . ... ||| .|... .|. | .... .. .| .| |.
vhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqyk
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 200-357 | 7.1e-13 | 43.3 | In-house | 127-285 (307) | alignment | ||
Range on Protein: 200-357
Range on HMM: 127-285/307.0
ELKAKICRKFWPEKgSKKDFPALSIQASDDHSETH--MKTFNLTVTEKK----QDHQT-VLMHFYEWADaSKLPEYMLDMRASIKlqYIRSSKKTGvcIG
| . | | |.||. .. . . .. . .. .. ....... .... .|.. | |. .| | || || . |. .|. .|. .
eknrkkcakYWpie.devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkD.skvPevargllklie..qvrelykln..rs
PIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
||.. | .||.. .|. ..|... .. .|..| ||. .. || .. |. |...
PivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldy
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 200-358 | 2.9e-10 | 34.5 | In-house | 137-295 (330) | alignment | ||
Range on Protein: 200-358
Range on HMM: 137-295/330.0
ELKAKICRKFWPEKGSKKdFPALSIQASDDHSETH--MKTFNLT----VTEKKQDHQTVLMHFYEWADASkLPEY---MLDMRASIKlqyirssKKTGVC
| | . | ..||..|. . . .. |. . .. | .. |..|. . .|| | | .| ||.. . .| |. .
erkeekcaqywPdeGlvt.yGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvG.vPfepiGmlkllkkvk.......klnqqs
IGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFA
|||.. |..|| . . ..| .. |. |..| |... ...|| .| | ..|...
agpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 200-359 | 8.1e-10 | 33.2 | In-house | 109-269 (274) | alignment | ||
Range on Protein: 200-359
Range on HMM: 109-269/274.0
ELKAKICRKFWPEKGSK---KDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADAsKLPEY---MLDMRASIklqyIRSSKKTGVCIGP
| . . | ...|.. . . . ..|. .. .. . . .|.. . .. .. . . . .| | | |. .||. . . .| ... ..|
eaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdh.ksPddantlldlvlev....eesreeenaklap
IMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAV
... |. |. . .. .|.| | .. ||. | .... ....| | .| | ..|....
vvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 200-344 | 1.1e-07 | 25.9 | In-house | 136-278 (297) | alignment | ||
Range on Protein: 200-344
Range on HMM: 136-278/297.0
ELKAKICRKFWPEKGSKKdFPALSIQASDDH--SET-HMKTFNLTVTEKKQDHQTVLMHFYEWADASK--LPEYMLDMRASIKLQYIRSSkktgvCigPI
| | |...||..||. . . .. .| .. ...| | .... .|| | . . . .|..| . | | | ||
eegvkqckrywpdeGsev.yhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrs.....c..pi
MLVCATGVEKCAIYATIDIIVSRITEE-HRVGFKETMSAIKMQRFGCFRTV
.. | |. .. .| ||....|.. ... |. .. || | .|
vvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktk
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 201-344 | 2.6e-08 | 27.9 | In-house | 108-257 (290) | alignment | ||
Range on Protein: 201-344
Range on HMM: 108-257/290.0
LKAKICRKFWPEKGS--KKDFP--ALSI--QASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADAS--KLPEYMLDMrasikLQYIRSSKKTGVCIG
. | ..||.. . . . |.. . ...|. .....|. . .. .. . .|. |.| . . | ..|.. |. .|.| |
keqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkf.....lfkvresGslssdvG
PIMLVCATGVEKCAIYATIDIIVSRITEEHR---VGFKETMSAIKMQRFGCFRTV
| .. |..|. . .. .| .. .| ... | |... ... .|.| .|
pavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqta
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 202-360 | 1.4e-16 | 55.4 | In-house | 128-281 (288) | alignment | ||
Range on Protein: 202-360
Range on HMM: 128-281/288.0
KAKICRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLDMRASIKlqYIRSSKKTGvcIGPIMLVCATG
. | ..||... .| . . ... ... .... . .| . ||.. .. ... |.| . || .. . .. . ... |||. .|. |
gktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhg.vPeskapllellr..qvkvanqad..tgpiivhCsaG
VEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAVT
| . .. ..| .. .. || . .|.. ...||. |. | |.|.. .
vGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsliee
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 202-360 | 1.4e-14 | 48.9 | In-house | 89-244 (250) | alignment | ||
Range on Protein: 202-360
Range on HMM: 89-244/250.0
KAKICRKFWP-EKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMldmRASIKLQYIRSSKKTGVCIGPIMLVCAT
. | . ..|| || | .|. .. ... .... |. ..|... . . .|| | | . ||.. .| ..|. ... . .|... |..
sektyhqywPvekaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkg.vPeva...tavLellkkvqasqqqagnaPvivqCsa
GVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAVT
|| . . .|| .. |. .|. | . . ... .| . .. |. |...|. ..
GvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 202-356 | 2e-14 | 48.4 | In-house | 128-278 (318) | alignment | ||
Range on Protein: 202-356
Range on HMM: 128-278/318.0
KAKiCRKFWPEKGSKkDFPALSIQASDDH--SETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKlPEYMldmraSIKLQYIRSSKKTG--VCIGPIMLV
||| . ..||.|||. . .| ...... |. ...|..| ||... | |. .|.| . || . |. .|...|. |||.
kak.vhryWPskgsr.sygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegv.pesg.....aslldlvrqvskaqqksgagpivvh
CATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
|..|| . .. ..||.. || .| | .|.. .. || .| | ..|..
CsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvlle
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 202-359 | 2.9e-14 | 47.8 | In-house | 123-291 (297) | alignment | ||
Range on Protein: 202-359
Range on HMM: 123-291/297.0
KAKICRKFWP-EKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHF--YEWADA--SKLPEYMLDMRASIKLQYIRSS-----KKTGVCI
. |...|| |..| ..| ||.. ....| . |. |.... |.... ..|| | | . . .||.. .. . .. ...| .
grlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghps
G-PIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAV
| ||.. |..|. . ..|.|| .||. |. | ||.. .. || .| | .. .|.
gPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyal
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 202-360 | 1.4e-12 | 42.4 | In-house | 127-285 (305) | alignment | ||
Range on Protein: 202-360
Range on HMM: 127-285/305.0
KAKICRKFWPEKGSK-KDFPALSIQASDDHSETHMKTFNLTVTE---KKQDHQTVLMHFYEWADASkLPEYMLDMRASIKLQYIRSSKKTGVcigPIMLV
. . ||..|||. .. |.| .|.. .. .. . . .|... .|.... . ... .| | |.. . || . .| || |.. .
gkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhG.vpqfatsllslikrvqkdqkkdkgv...pllVh
CATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAVT
| || . .. ..|| . |. .| | . | . ... .| . | | ..| . .
CsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 202-358 | 4.6e-11 | 37.2 | In-house | 130-279 (315) | alignment | ||
Range on Protein: 202-358
Range on HMM: 130-279/315.0
KAKICRKFWPEKgsKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWAdASKLPEYMLDMrasikLQYIRSSKK-TGVCIGPIMLVCAT
. . . |.||.| | . ... .. .|.. |.|. ... .. | .|. | ...|.| . . ...|| |. .|.|.. |
ekrkaekywpdk..kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswp.dmgvpkytipl.....mnlirtvkqhhtnsvgaivvhcsa
GVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFA
|| . . |.| .. .. |. . . . .. .| . ... | ..|..
GvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletf
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 202-347 | 2.1e-10 | 35.2 | In-house | 125-265 (281) | alignment | ||
Range on Protein: 202-347
Range on HMM: 125-265/281.0
KakiCRKFWPEKGSKKDFPALSIQASDDHSETH--MKTFNLtVTEKKQDHQTVLMHFYEWADA--SKLPEYMLDMRASIKlQYIRSSKKtgvciGPIMLV
| | ..||.. |. . . .. ..... ..|.| .|. . . . ... | | . .. .|. |. .. .. ....| |...
k...ChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevl.kltekktk.....aplvih
CATGVEKCAIYATIDIIVSRITEE-HRVGFKETMSAIKMQRFGCFRTVGPY
|..|| . | ..| .|.....| ... |... .. .| .|| |
CsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqy
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 202-360 | 8.7e-10 | 32.8 | In-house | 118-279 (287) | alignment | ||
Range on Protein: 202-360
Range on HMM: 118-279/287.0
KAKICRKFWPEKGSKKDFPALSIQASDDH---SETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKLPEYMLDMRASIKL-QYIRsSKKTGVCIGPIMLV
. | |.|||. |. . | | .... | | .. . .....| | . | . .| .. |.| .. . .||...
arlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhie.lardasevGPlvvh
CATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAVT
. .|. . |. .. ..||| . || .. ....| . ..| . .| |. . |
ddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyykt
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 202-355 | 9.2e-10 | 32.3 | In-house | 129-284 (563) | alignment | ||
Range on Protein: 202-355
Range on HMM: 129-284/563.0
KAKICRKFWPEkGSKKDFPALSIQA--SDDHSETHMKTFNLTVTE---KKQ-DHQTVLM--HFYEWADASkLPEYMLdmrasIKLQYIRSSK-KTGVCIG
... | .||. ... ||... .. .. ..|. . .. ||| |.. . . |. .| | . ||. | .|.... |. . .|
grrkcdvYWPk.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhg.vPehsl.....pvLifvkkssaankaeaG
PIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLM
||. | .|| . .| .| .. .| .|. | ... |..|| . | | . |.
PivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdall
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 202-361 | 1.3e-08 | 28.8 | In-house | 133-286 (290) | alignment | ||
Range on Protein: 202-361
Range on HMM: 133-286/290.0
KAKiCRKFWPEK-GSKKDFPALSIQASD-DHSETHMKTFNLTVTEKKQDHQTVLMHFY--EWADASklpeymLDMRASIKLQYIRSSKKtgvCIGPIMLV
||| | ...||| | | .... | |. ..... |.| .|.. .. .| |. | | | . . . |. .|. .| ||...
kak.ceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdks......valstlallrtlrilrk...asGpvvvh
CATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAVTT
|..|. . ...|.. . ... . . ... |.. | . . | . |.|... .
csaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkdf
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 202-343 | 1.9e-06 | 22.2 | In-house | 90-226 (239) | alignment | ||
Range on Protein: 202-343
Range on HMM: 90-226/239.0
KAKICRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLdmrASIKLQYiRSSKKTGVCIGPIMLVCATG
. | |...||. || .... .. .. ..|| .. . ... || | | .|.| | . |. . .| . | .. |..|
hkkkchqywpdstskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkg.vpqyat...avlglrr.kitkdslpgarpwvihcsag
VEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRT
| . . || .. . ... | . . ||. .| .|
vgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqt
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 202-343 | 1.9e-06 | 22.2 | In-house | 89-225 (239) | alignment | ||
Range on Protein: 202-343
Range on HMM: 89-225/239.0
KAKICRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLdmrASIKLQYiRSSKKTGVCIGPIMLVCATG
. | |...||. || .... .. .. ..|| .. . ... || | | .|.| | . |. . .| . | .. |..|
hkkkchqywpdstskycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkg.vpqyat...avlglrr.kitkdslpgarpwvihcsag
VEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRT
| . . || .. . ... | . . ||. .| .|
vgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqt
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 203-346 | 3e-11 | 37.1 | In-house | 124-264 (515) | alignment | ||
Range on Protein: 203-346
Range on HMM: 124-264/515.0
AKI-CRKFWPE-KGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKLPEymldmrASIKLQYIRSSK-KTGVCIGPIMLVCA
|| | |.||. | | .... .. | . .|||. .. . || || | .. .| |..|. | ..| |... |.
dkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkh......tssllklikevkadhgqythpliihcs
TGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGP
.|| . .. .|| .|... . . | ... |. .| .|
aGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeq
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 203-358 | 5.7e-11 | 36.9 | In-house | 103-264 (270) | alignment | ||
Range on Protein: 203-358
Range on HMM: 103-264/270.0
AKICRKFWPEKGSK-KD--FPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKLPEYMLDMRASIKLQYIRSSKKTGVC---IGPIML
| | ..||.. . . . ... |. .. |. . .|...|| . .. | ....| | . .| .... |. .| ... .|..
rkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllv
VCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFA
|. ||.. . ..||.| . |...| . ..... .| . ... | . . ....|
HcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveya
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 203-356 | 4.6e-10 | 33.6 | In-house | 123-288 (296) | alignment | ||
Range on Protein: 203-356
Range on HMM: 123-288/296.0
AKICRKFWPEKGsKKDFPALSIQASDDHSETHMKTFNLTVTEK-----------KQDHQTV-LMHFYEWADASKLPEY---MLDMRASIKLQYIRSskKT
|| . ..||.|. |... . .. .. ...|. .. .| | | . .| |... || |.| ....| ..| . .
akmypsywpnks.keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekv..de
GVCIGPIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
||.. |. |. . .| .||. . . .|..| . | . .. .| . .| | ..| .
dpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlle
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 203-347 | 4.6e-09 | 30.5 | In-house | 125-266 (314) | alignment | ||
Range on Protein: 203-347
Range on HMM: 125-266/314.0
AKICRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTV--LMHFYEWADAsKLPEYMLDMRASIKlqYIRSSKKTgvCIGPIMLVCAT
. | |.|||.... . . . .. ..| ...|... ....|. . . ..| |.| . | . . . .. . .|.. |.|.. | .
rvkClkyWPedtevygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdh.dvPvsatgllklvr..rvkksqee..eaGrivvhCsa
GVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPY
| . .. .|||.. | .|. | ... ... .. | |
GaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqy
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 203-359 | 1.1e-08 | 29.4 | In-house | 114-267 (283) | alignment | ||
Range on Protein: 203-359
Range on HMM: 114-267/283.0
AKICRKFWPEKGSKkDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKLPEYMLdMRASIKLQYIRSSKkTGVCIGPIMLVCATGV
. | ..||..||. |. . . .. .. . .|.. . ..|.|. | | . | . . .|. ..| . | |||.. |.||.
rikCsqyWPkrGse.dyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqai.inslvkfnkvislq.teskkgPivvhCstgi
EKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAV
. |.. .. | . | | ... .. || . .| . | |. .. |.
Grtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqal
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 203-341 | 7.5e-07 | 23.6 | In-house | 84-222 (237) | alignment | ||
Range on Protein: 203-341
Range on HMM: 84-222/237.0
AKICRKFWPEKGSKKDFPAL--SIQASDDHSETHMKTFNLTVTEKKQDHQTVL-MHFYEWADAsKLPEYMLDMRAsIKLQYIRSSKKTGvCIGPIMLVCA
. | |.||. . . | |.. .. |. .... |.. .... . . .| | | .|.. . .. . | |.. || .. |.
elkchkywpstdqpaaygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdr.gvpqqtaallr.frkniinrsphvs.esgpwiihcs
TGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCF
.|| . .|. || .. . |.. | . . .|. .|
agvgrtgiflvidamlrqakekkvvdiynyvysieedrpyii
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 204-357 | 1.2e-14 | 48.9 | In-house | 124-274 (280) | alignment | ||
Range on Protein: 204-357
Range on HMM: 124-274/280.0
KICRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKK--QDHQTVLMHFYEWADAsKLPEYMLDMRASIklQYIRSSKKtgVCIGPIMLVCATG
. | ..|||.. . .. .|.. . ..... . . .|....|. .... . . . .|.| ..|. |. . . .|. .. . |... |..|
vkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdh.gvPddsadflefv..ervrklrs..gkeePvvvhCsaG
VEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
... .. .... .. | ... | . .. .. || .|.. | || ..|
igrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 204-356 | 1.1e-13 | 45.9 | In-house | 134-283 (293) | alignment | ||
Range on Protein: 204-356
Range on HMM: 134-283/293.0
KICRKFWPEKGSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLDMRASIklQYIRSSKKTGVCIGPIMLVCATGVE
. | ..||.. . . .... ... .. . .|.....|. ... .|| |.| || . . . . .|..... .||. |. ||
vkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhg.vPektktlldfv..rtvreaiektaskrPivvhCsaGvG
KCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMK
. .. ..| ....|.|| | ........|. |. | . ...
RtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvld
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 204-347 | 6.2e-12 | 40.0 | In-house | 126-266 (315) | alignment | ||
Range on Protein: 204-347
Range on HMM: 126-266/315.0
K-ICRKFWPE-KGSKKDFPALSIQASDDHSETHMKTFNLtVTEK-KQDHQTVLMHFYEWADASklpeymLDMRASIKLQYIRSSKK-TGVCIGPIMLVCA
| ||..||. |. .| ..... . .. | . . .| || | .. .. .| || | | ..| |..|. | | .... |.
kikcrqywPdrkadsvefGsikvellsleadtdgvarkl.vtrkseesrtvtqfqftewPdkG......vdkqtssllklikevkadngkkefsllvhcs
TGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPY
.|| . . .|| .|..| ... | ... .. .| .| |
aGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeey
|
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| subfamily_PTPN14_pd | Subfamily PTPN14 | 204-357 | 3.1e-08 | 28.0 | In-house | 133-295 (300) | alignment | ||
Range on Protein: 204-357
Range on HMM: 133-295/300.0
KICRKFWPEKGSKK---DFPALSIQASDDHSETHMKTFNLTVT--EKKQDHQTVLMHFYEWADASkLPEY---M---LDMRASIKLQYIRSSKKtGVCIG
. . |..|...||| .| ... .. . . | |.. |.. . . . . .|.| .|| . |.. |.. . ....
eksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhg.vPeDvkgflsyLeevqsvrrktnseves.keskP
PIMLVCATGVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKF
|... |. || . . . |.... . .... |.... .. || .|.. | ..|.|.
PvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvliky
|
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| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 205-358 | 1.5e-10 | 35.7 | In-house | 132-283 (319) | alignment | ||
Range on Protein: 205-358
Range on HMM: 132-283/319.0
ICRKFWPEKGsKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDH---QTVLMHFYEWADAsKLPEYMLDMRASIKlqYIRSSKKTgVCIGPIMLVCATG
..|.|||. ... | .. ... .. .|.. .|... . . .. ||.| . ||. . . . .| || |.. |||. |. |
klkkywpeen.feeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdh.dvPekatslldllk..rirksrek.tqsgPivvhCsaG
VEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFA
| . . ..|... |. || . .|.| ...|| .. |. | |....
vGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleav
|
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| subfamily_PTPN13_pd | Subfamily PTPN13 | 205-347 | 4.2e-10 | 34.4 | In-house | 118-258 (273) | alignment | ||
Range on Protein: 205-347
Range on HMM: 118-258/273.0
ICRKFWPEKGSKKDFPA--LSIQA--SDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASkLPEYMLDMrasikLQYIRSSKKTGVCIGPIMLVCAT
|...|||. .|| | .. .... ....... .| .. .. . ..| .| | . | ... ||... .. |||. |..
kchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhg.vPssaael.....lqfvaevrrlqtdagPivvhcsa
GVEKCAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPY
|. . .. |||... | .. . ||.. .. || | .| |
GiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqy
|
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| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 207-358 | 4.6e-07 | 24.1 | In-house | 112-259 (267) | alignment | ||
Range on Protein: 207-358
Range on HMM: 112-259/267.0
RKFWPEK-GSKKDFPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFY-EWADASKLPEYMLDMRAsiklqyIRSSKKTGVCIGPIMLVCATGVEK
|.||| | | | . |... | .. | . | . |.. . | ...| .| .. |. . . | . .. |... |. || .
rlfwPPkmgqakkyqdltvehslekeendyqiitlelkfknesahnvtlyyykkwnintnnkpylkplfg......ilaknqlengnrPlvvacsdGvGr
CAIYATIDIIVSRITEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFA
. .|| . |. .| . . . |. || | | | |.| ..|
sGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaeya
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 219-366 | 9.5e-06 | 19.8 | In-house | 131-278 (285) | alignment | ||
Range on Protein: 219-366
Range on HMM: 131-278/285.0
FPALSIQASDDHSETHMKTFNLTVTEKKQDHQTVLMHFYEWADASKLPEYMLDMRASIKLQYIRSSKKTGVCIGPIMLVCATGVEKCAIYATIDIIVSRI
| | .. . |. | ..| . . . . . . |. . | .. . || || . |..|| . | . || ||
fgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatiri
TEEHRVGFKETMSAIKMQRFGCFRTVGPYSTACEMLMKFAVTTGVVHD
|. . . . . .. || . .. . .||.. . |||
menpniemldivremramrfqavqshmqflflyvvlmeyfigegvver
|
|||||||||
| PTPc_DSPc_SM00012 | 253-355 | 6e-16 | 53.9 | In-house | 4-104 (105) | alignment | |||
Range on Protein: 253-355
Range on HMM: 4-104/105.0
LMHFYEWADAsKLPEYMldmraSIKLQYIRSSKKTGVCI---GPIMLVCATGVEKCAIYATIDIIVSRITEE-HRVGFKETMSAIKMQRFGCFRTVGPYS
.|...| | ..||.. . |...|. || . .|....| .|| ........||.......| ..| ..........|| |...| |.
hyhytgwpdh.gvPees.....dsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqyl
TACEMLM
...|.
flyrall
|
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