Synonym: CELE_F36H1.3, CELE_F36H1.3
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 74-237 | 1.8e-07 | 24.8 | In-house | 52-156 (349) | alignment | ||
Range on Protein: 74-237
Range on HMM: 52-156/349.0
NTMHDIFDRDTFAFRLEHCVHPDALNRHSVQTEAfetftttvtsmgvdglakeyletlvpflpvgyfersifdkntefkknrykdvpcndktrvilkDGY
| .||. . .|.. ... . ..| . |
nrykdilPyehsrvklkkslksskvikastsesd...............................................................sgk
PGDYVHANYVKGTK----PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDT
. ||. |||.| |. .| || || | | ....| .|| . | . |.. ||. |. .
lddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcdiywqel
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 95-384 | 4.4e-181 | 594.9 | In-house | 1-290 (290) | alignment | ||
Range on Protein: 95-384
Range on HMM: 1-290/290.0
PDALNRHSVQTEAFETFTTTVTSMGVDGLAKEYLETLVPFLPVGYFERSIFDKNTEFKKNRYKDVPCNDKTRVILKDGYPGDYVHANYVKGTKPMFILTQ
|||||||||||||||.|...|....||.|||||||.|.|.|||.|.||.||||||||||||||||.|||||||||||||.|||||||||||.|.||||||
pdalnrhsvqteafekfasdvvkknvdelakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilkdGydGdyvhanyvkGlkamfiltq
GPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIAL
|.||||..|||||||||.||||.|||||||.|..|||.|.|..||.|||||||||.|.|....|.....|.|.|.||.|||.|||.|.||..|||||.||
GalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksval
SNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVAFKYIE
|.||.|||||.|||..||.||||||||||||||.|||||.|.||.||.....|||||.|..||||||.|.|||.|||..||||..|||||
stlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldlGkdfkyie
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 95-376 | 2e-67 | 223.1 | In-house | 6-288 (297) | alignment | ||
Range on Protein: 95-376
Range on HMM: 6-288/297.0
PDALNRHSVQTEAFETFTTTVTSMGVDGLAKEYLETLVPFLPvgyfeRSIFDKNTEFKKNRYKDVPCNDKTRVILKDG----YPGDYVHANYVKGTKP--
. .|. ........ . . .. .| .|. | | . . .||. . .||||||....| .||.||. . ||..|.||.| .
dallesipiplsvldlllllekansktllllefeellslkpd.....ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydllt
-MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRpKCEPYFPDTEGqvlTFGEITVTCTESTTpDNHTQLKMLTVMDkkSGKSHKLYHYKIITW
||.|||||..| | |||| ..|| .| ||..|.|.|| ||..|.|...| |.|..|||... .. ... . |.| . .|.|....|. . |
rkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh.ldgytvrtlevtn..ngesrtvthfqytgw
PDKSIALSNLAILRTLRSLRK------MPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
|| .. | .|. |. .|. .||..||||||.||||||.|. ..| .. . . . |. .| .| ..||.. || | .|.|.|
pdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallel
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 100-370 | 3e-40 | 132.7 | In-house | 6-283 (310) | alignment | ||
Range on Protein: 100-370
Range on HMM: 6-283/310.0
RHSVQTEAFETFTTTVTSMGVDGLAKEYLETLVPFLPVGYFErsIFDKNteFKKNRYKDVPCNDKTRVILK--DGYPGDYVHANYVKGT--KPMFILTQG
.| .|.| | . .|..||.|.| . .| . |. ..|||| || | |..|| || .||.|||||| . || .||
hhlkylkalenfiiateklgieglvkqyrkldakqdssltye..aykky..mhknrysdvvcldtsrvklkidksryedyihanyvktnylrstficsqg
PLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTeGQVLTFGEITVTC-TESTTPDNHTQLKMLTVMDKK-----SG--KSHKLYHYKIITW
||. | .|.|||..|| .| .|| |.||||| |.| | |.| | || .||. . .| . | |. | .. | |
plqhtiidfwrmifqeraesilllckvgeegrpkcvgywpsl.gvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnw
PDKSIALSNLAIL--RTLRSLRKmpGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLV
||. . . . | | .|. || |||||||..|... .|... . | .|. ... ... |. .| . |||..
pdrgvpdekchtvpqrllaqvrh..gpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliid
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 102-375 | 1.8e-73 | 242.8 | In-house | 4-284 (288) | alignment | ||
Range on Protein: 102-375
Range on HMM: 4-284/288.0
SVQTEAFETFTTTVTSMGVDGLAKEYLETLVPFLPvgyFERSIFDKNTEFKKNRYKDVPCNDKTRVILKDGYP---GDYVHANYVKG--TKPMFILTQGP
....| .. . ... |. ||..|. | | . . ...|.. . ..||||.|....|..||.|.. . .||..|.|..| .| ||.||||
eisveellklvlkllangltglleefeellsllpd...ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgP
LKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDteGQVLTFGEITVTCTESTTpDNHTQLKMLTVMDK----KSGKSHKLYHYKIITWPDKSI
|..| | |||| ...| | ||..|.|.|| ||..|.|. |..||.|.||||... .. ... . |.| .. ..|.|.. .|. ..||| ..
lpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl..ggsltygditvtllseev.lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgv
ALSNLAILRTLRSLRKM----PGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
| ..|. || .||. .||.|||||||.||||||.|... ..|.... . . ..|. .|..| ..||. ||... ||.|.
pdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealle
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 104-379 | 1.1e-77 | 256.7 | In-house | 25-301 (308) | alignment | ||
Range on Protein: 104-379
Range on HMM: 25-301/308.0
QTEAFETFTTTVTSMGVDGLAKEYLETlVPFLPvgYFERSIFDKNTEFKKNRYKDVPCNDKTRVILkdGYPGDYVHANYVKGT----KPMFILTQGPLKD
.. . .. .| .|. | . | ..|.|.. . ..||||||....|..||.| . . ||..|.||.| . ||.|||||..
klsvldllkllekaldlglleeefeel.lsvkp..lleysvallpenkdkNrykdilpydhsRVkl..degsdYInAsyvdgyssklprkfIatqgPlpn
TAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEG-QVLTFGEITVTCTESTTpDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLA
| | |||| ...| | ||..|.||||.||..|.|...| ..|..| .|||... .. ... . |.......|.|....|. ..||| .. | .
tvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseev.lddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspei
ILRTLRSLRKM--PGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVA
.|. |. .||. .||||||||||.||||||.|... ..| .. . . ..|. .|..| ..|| ||| | .|.|..
lldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 105-379 | 3.5e-43 | 142.7 | In-house | 3-273 (288) | alignment | ||
Range on Protein: 105-379
Range on HMM: 3-273/288.0
TEAFETFTTTVTSMGVDGLAKEYLETlvpflPVGYFERSIFDKNTEFKKNRYKDVPCNDKTRVILKDGyPGDYVHANYVKGTKP--MFILTQGPLKDTAM
.| .. | ...|.|| ||| .. | . ...| .. ..||...|. | ||| |.| | |..|| | .| .| .| ||. |
kevinawirlvlqiaveglkkeyrds.....pneasidiidsfianptrdryenlprcditrvklsdd.pdfyiaanvvssakykrrlicaqaPlngtie
DIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEItVTCTESTTPDNHTQLKMLTVMDKKSGKSHK-LYHYKIITWPDKSIALSNLAILR
.|.|.|...| | |||||.| |..| . ||| |. .| . | . | . .|. .. .| |. .. . . . |.|... . |. ||
elWkmllesdveyivmlcellekGkeksaeyfPsklGekarigrl.ctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplr
TLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVA
| |... |||||.|||.|||||.. | . .. | |. | | ...| ||| . .|. .
llevlkslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelll
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 107-376 | 2.8e-43 | 143.0 | In-house | 5-286 (563) | alignment | ||
Range on Protein: 107-376
Range on HMM: 5-286/563.0
AFETFTTTVTSMGVDGLAKEYLETLVPfLPVGYFERSIFDKNTEFKKNRYKDVPCNDKTRVILKD--GYPG--DYVHANYVKGTK--PMFILTQGPLKDT
|. . . . | |...|. . ... . .|. . .|||| .. |..|| |.. | . ||. |||..| . || ||||||||
efakhvaslhadgdigfseefealqse.tiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdt
AMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDteGQVLTFGEITVTCTESTTPDNHT----QLKMLTVMDKKS-GKSHKLYHYKIITWPDKSIALS
. | |||. .. || | |. .| |.|| ||. |.| ...|.|...|| .|. . | ..| | . .||. . .. ..|. .|||.. .
fddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPeh
NLAILRTLR----SLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
.| | . . .. ||||||||||.|||||. ... . . . .| .... .| | . || ||. | .|.|..
slpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdallea
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 108-379 | 1.7e-76 | 252.9 | In-house | 5-278 (317) | alignment | ||
Range on Protein: 108-379
Range on HMM: 5-278/317.0
FETFTTTVTSMGVDGLAKEYLETLVPFLPvgyfERSIFDKNTEFKKNRYKDVPCNDKTRVILKDGYP---GDYVHANYVKGT--KPMFILTQGPLKDTAM
.. . .. ... .| .|. . | .|. ..|.. . .||||.|....| .||.|.. . ||..|.||.| |. ||.|||||..|
lllalldllksdftalleefedllslkld....tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntve
DIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDteGQVLTFGEITVTCTESTTpDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRT
| |||| ..|| | ||.|| |.||.||..|.|. |..||.|..|||... .. ... .| |.| |.....|....|. ..||| .. | .|.
dFwrmvweqgvtvivmLteleelgrekcaqYwpl..getltygdftvtllseee.lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldf
LRSLRKM----PGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVA
|. .|. .||..||||||.||||||.|... ..| .. . . . |. .|..| ..||. || | .|.|..
leavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkr
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 109-376 | 8.5e-57 | 187.4 | In-house | 4-289 (297) | alignment | ||
Range on Protein: 109-376
Range on HMM: 4-289/297.0
ETFTTTVTSMGVDGLAKEYLEtLVPFLPVGYFERSIFDKNteFKKNRYKDVPCNDKTRVILK---DGYPGDYVHANYVKGTK--PMFILTQGPLKDTAMD
| . . | ..| || |||.| . ..| |..| | .||||.|| | |.||| |. . ||..||.| | | || |||||| | |
eelvayvkekgkrGlskeyae.irnepveGtflasklran..leknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsd
IWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTESTTPDNHtQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTL
|||| .. | | | ..|.|| || |.|..|... ||...|. | . ... . ..|.. . | ..| |. |.....||| . | ..| |
fWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedy.kvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvl
RSLRKMP-----------------GPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
. |.. ||||||||||||||||..... . | . . |. .| | |.|.. || . |.|.
ekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 111-377 | 1.8e-47 | 157.0 | In-house | 17-290 (298) | alignment | ||
Range on Protein: 111-377
Range on HMM: 17-290/298.0
FTTTVTSMGVDGLAKEYLETLVPFLPVGYFERSIFDKNTEFKKNRYKDVPCNDKTRVILKD---GYPGDYVHANYVKGTK--PMFILTQGPLKDTAMDIW
... .... |.|.|. . . .| .. |.. ||||| |. |..||.|.. .||. | .... | . ||.||.||. | | |
laavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFW
RMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQvlTFGEITVTCTESTTPDNHTQLKmLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRS
||| .| ...| || .| | .. |.. |.||.. . |.|||||. .. . . .. | |.| .||. |.... . . ..||||... . ..| ||
rmvteedigtiVmltnleeldktkyhkywPdegke..tygeitvsllskeefadlivrk.lkvskkkeekerevrqlhftsWpdkgvpenatsvldllrk
LRK---MPG--PIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLG
|. | |..|.||||.||.||| ||. . . . . . |...|. | ..|| .|| . ||.|.
vrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleal
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 112-381 | 1e-44 | 147.9 | In-house | 14-287 (319) | alignment | ||
Range on Protein: 112-381
Range on HMM: 14-287/319.0
TTTVTSMGVDGLAKEYLETLVPFLPvgYFERSIFDKNTefKKNRYKDVPCNDKTRVILK---DGYPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWR
.... | | .|.||. . . |. . ..| |||||... |.|||.|. . ||. |... | . || ||.||..| | ||
lkalastgetllekefkllkeavnd..tfdsaskeenk..kknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWr
MVLQEGVAAICMLCELIENGRPKCEPYFPDTegQVLTFGEITVTCTESTTpDNHTQLKMLTVmDKKSGK--SHKLYHYKIITWPDKSIALSNLAILRTLR
|| .|.. . ||..| |... |.. |.|.. .. ..|...|| | .. . |.. .|||.. . .. |.. |||. . . ...| |.
mvWeeessivvmltklveklkvklkkywpee..nfeeyGrlivtleeeee.ledyiirklkl.nkkssevetRevkhfqyteWpdhdvPekatslldllk
SLRK-----MPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVAFK
.|| ||||||||||.|||||| .... . . . . |. .| | || || .. ||.|. |..
rirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 114-374 | 2e-50 | 166.5 | In-house | 19-294 (306) | alignment | ||
Range on Protein: 114-374
Range on HMM: 19-294/306.0
TVTSMGVDGLAKEYlETLVPFLPVGYFERSIFDKNTEFKKNRYKDVPCNDKTRVIL-KDGYPG-DYVHANYVK----GTKPMFILTQGPLKDTAMDIWRM
. .|.. |. .|. |.| ...|. .|.. .||||| . |.||||| ... || ||. |||.| |.. .| ||| |..| | |||
eeeslekagfeeef.eelqqeeakkllsrkegakpenkeknryknilPfDhtrvilkepsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrm
VLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLtFGEITVTCTESTTPDNHtQLKMLTVM-DKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSL
|.|| | |. . .| |. || .|.||.| . .|.|.||...... .. .|. |.| ||.........|. .|||... . |.| |. .
vwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvseksladY.ilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledv
RK--------MPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADL---VRAVRHCRLNSVQMDTQYLMLVEAIL
.. .||||||||||||||||| |.. . . . . . |. |. ||. | ||...|| .. .||
nrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaik
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 116-389 | 5.5e-55 | 181.5 | In-house | 11-288 (307) | alignment | ||
Range on Protein: 116-389
Range on HMM: 11-288/307.0
TSMGVDGLAKEYlETLVPFLPVGYfERSIFDKNTEfkKNRYKDVPCNDKTRVILK-DGYPGDYVHANYVK-GTKP-MFILTQGPLKDTAMDIWRMVLQEG
.||. | |. . | | | |. ||. ||||.||.| ||.|...| || ||.||||. .|| || .||||..| ..| |..||
ldkgvqalvdef.rvlakktpegv.tveafsantd..knryqdvkcqdkgrivvkfdglasdyihanylgiaikpkkficaqgplentqysfwamaiqek
VAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCT------ESTTPDNHTqLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSL
| .. |||..|| .. ||| |.| ||| |.||| . | . . .||.. ... |. . ..|| . |.. |||. . ||. . | .
vesvimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedl.invttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleav
RKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRP-ADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVAfKYIEDPKSL
| |.|||||||.||.|| || . . ...|. . .||. .| | ..| . ||| | .|. . .| | . |
rydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyfle.lyketyeel
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 116-376 | 3.1e-47 | 156.0 | In-house | 16-278 (288) | alignment | ||
Range on Protein: 116-376
Range on HMM: 16-278/288.0
TSMGVDGLAKEYlETLVPFLPVGYFErsIFDKNTEFKKNRYKDVPCNDKTRVILKD---GYPGDYVHANYVKGTK--PMFILTQGPLKDTAMDIWRMVLQ
.. .|. .|| ..| .. . . . |||||... | .|| ||. . ||. |.|..|.| .| ||||| || | |..| .
sarnrtgfseey.nsLaalektksvt..agrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvye
EGVAAICMLCELIENGRPKCEPYFPDTEGQVlTFGEITVTCTESTTPDNHTQLKMLTVmdkKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLR---
. . | || ||.|.|. ||| |.||.. .. .|..||| .|| . ..... |.| . |... .. .|. .|||... |. .| || .
nktstivmltelveggktkCeeYWPdadkpk.nyGsvtvtlveskeledfvlrkllle...kkkteleitqyqylaWpdhgvPeskapllellrqvkvan
KMP-GPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
. |||.||||||.|||||| |.. . . . . |. | .|. | . || .|| . |..|.|
qadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsl
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 119-375 | 4.1e-72 | 238.2 | In-house | 10-270 (273) | alignment | ||
Range on Protein: 119-375
Range on HMM: 10-270/273.0
GVDGLAKEYLETlVPFLPvgYFERSIFDKNTEFKKNRYKDVPCNDKTRVILkDGYPGDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAI
|...|..|. . ... | ....|.. . ..||||||....|..||.| .. . ||..|.||.| .|. ||.|||||..| | |||| ...| |
gltllleefell.lslkp..lltysvallpenkdknrykdilpydhsrvkl.gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrvi
CMLCELIENGRPKCEPYFPDTEGQ-VLTFGEITVTCTESTTpDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK------M
||.||.|.||.||..|.|...|. .||.|..|||... .| ... . |.. ....|.|.. .|. .||| .. | .|. .. .||
VmLtelvelgrekcaqYwpleggelsltygkftvtllseet.kddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealps
PGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
.||.|||||||.||||||.|... ..| .. . . ..|. .| .| ..|| ||..| ||.|.
ngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 119-376 | 8.2e-71 | 234.6 | In-house | 25-303 (307) | alignment | ||
Range on Protein: 119-376
Range on HMM: 25-303/307.0
GVDGLAKEYLeTLVPFLPVGYFERSIFDKNTEFKKNRYKDVPCNDKTRVILKDGYP----GDYVHANYVKG----------TKPMFILTQGPLKDTAMDI
.. ||.||. .|... . ..|.||. . .||||||....| |||.|.. . .||..|.||. | ||.|||||..| |
fltgllkefe.kllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedF
WRMVLQEGVAAICMLCELIENGRPKCEPYFPDTeGQVLTFGEITVTCTESTTpDNHTQLKMLTVMDK-KSGKSHKLYHYKIITWPDKSIALSNLAILRTL
|||. ..|| .|.||.||.|.||.|| .|.||. |..||.|..|||... .. ... .. |.| |. ..|.|....|. ..||| .. | .|. .
wrmlweqgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh.ldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfi
RSLRK------MPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKA---FRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
. .|| .||..||||||.||||||.|. . ..| ... . . . |. .| .| ..|| || | ||.|.|
eevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 121-375 | 7.3e-34 | 112.3 | In-house | 23-286 (325) | alignment | ||
Range on Protein: 121-375
Range on HMM: 23-286/325.0
DGLAKEYleTLVPflPVGYFERSIFDKNTEFKKNRYKDVPCNDKTRVIL---KDGYPGDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGvAA
||.|.|. |.| ... . . | . .|||.|.| ||.||.| || ||. |.|.. | .|. .| || .| |.||.||. ..
dgfahef..gllp..sddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr.cs
ICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTESTTPDNHTQlKMLTVMDKKSGKSHKLYHYKIITWPDKSI---ALSNLAILRT-------LRS
. .. . ...| .| |.|. |. ||| . | . .. . ..| | . | |.. . ... .|.| . ..||.. ...
vvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvh.rvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservta
LRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
| .||.||||||.||||.|... .. ... . |. .|. | . |. || .. ||. .
ntkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealve
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 122-375 | 1.8e-67 | 223.0 | In-house | 21-275 (278) | alignment | ||
Range on Protein: 122-375
Range on HMM: 21-275/278.0
GLAKEYLeTLVPFLPvgyFERSIFDKNTEFKKNRYKDVPCNDKTRVILKD---GYPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAI
.| .|. .| | . ...||. . ..||||||....| .||.|.. .. ||..|.||.| .. ||.|||||..| | |||| ..|| |
llllefe.ellsfkl...dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvtti
CMLCELIENGRPKCEPYFPdteGQVLTFGEITVTCTESTTpDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK----MPGP
||.|| |.||.|| .|.| |..||.|..|||... .. ... . |.| ....|.|.. .|| . ||| .. | .|. |. .|. .||
vmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh.lddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrealedsngp
IVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
..||||||.||||||.|... ..| ... . . . |. .|..| ..||.. || .| ||.|.
vlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 124-378 | 3.4e-74 | 245.1 | In-house | 3-275 (284) | alignment | ||
Range on Protein: 124-378
Range on HMM: 3-275/284.0
AKEYlETLVPFLPVGYFERSIFDKNTEFKKNRYKDVPCNDKTRVILKDGYP----GDYVHANYVKGT-------KPMFILTQGPLKDTAMDIWRMVLQEG
.|. |.|. . . ....|.. . ..||||||....|..||.|| . .||..|.||.| |. ||.|||||..| | ||||....
eeef.eellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
VAAICMLCELIENGRPKCEPYFPDTeGQVLTFGEITVTCTESTTpDNHTQLKMLTVMDKK-SGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM--
| | ||.||.|||| ||..|.|.. |.|||.|..|||... .. ... . .|.. ... .|.|....|. ...||| .. | .|. || .|..
vrvIVmltelvengrekcaqYwple.gevltygdftvtllseev.kddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrelle
----PGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGK---AFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGV
.||||||||||.||||||.|... ..| ... . . ..|. .| .| ..||. ||... ||.|..
nlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 125-384 | 6.7e-76 | 250.7 | In-house | 16-284 (297) | alignment | ||
Range on Protein: 125-384
Range on HMM: 16-284/297.0
KEYLETLVPFLPVGYFERSIFDKNTefKKNRYKDVPCNDKTRVILkDGYPGDYVHANYVKGTK--PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCEL
... |.|.|.|. | .. ... .| .||||||....|.|||.| |. . ||..|.||.| . ||.|||||..| | ||||....| | ||.||
lkefeellpllllgslsvallpenl..eknRykdilpydhtRVkl.ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltel
IENGRPKCEPYFPDTEGQVLTFGEITVTCTESTT-PDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK------MPGPIVV
.|.||.||..|.|..||..||.|..|||... .. .... | |.| |...|.|....|. ...||| .. | .|. .. .|| .||..|
velgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlV
HCSAGIGRTGTFAAIEVGAQCLL---NGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVAFKYIE
|||||.||.|||.|... |.| . . . ..|. .|..| ..||. ||. | ||.|.| ....|
HCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltke
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 128-380 | 4.4e-22 | 73.1 | In-house | 28-286 (303) | alignment | ||
Range on Protein: 128-380
Range on HMM: 28-286/303.0
LETLVPFLPVGyFERSIFDKNteFKKNRYKDVPCNDKTRVILKDGypgDYVHANYVK-GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENG
.| .| .|| . | || ..|||. || | |...| | | |.||.|.. .. |||| || || |.|.|.... | . .| |
fekvvsylpps.vsknqfvkn..mdknrfvdvicldhskvklsds...syihasyleldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseyd
RPKCEPYFPDTEgQVLTFGEITVTCTESTTP--DNHTQLKMLTVMDKKSGKSHKLYHYKiiTWPDKSIALS-----NLAILRTLRSLRKMP--GPIVVHC
. . || . . | | | .. | . .||.|.| . . ...||| .|| .|| | . ||| | |
klggdsvfprnq.dflkfeersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhyk..awphnsipsdgspkfvkqiwqlqsvlrkysdstptvyms
SAGIGRTGTFAAIEVGAQCLLNGKAF-RPADLVRAVRHCRLNSVQMDTQ----YLMLVEAILDLGVAF
.| ||.|||| .| | . .| . || || .|| .| | .| | .|| |..
lsgcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehvldngick
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 135-377 | 8.5e-67 | 220.8 | In-house | 20-272 (278) | alignment | ||
Range on Protein: 135-377
Range on HMM: 20-272/278.0
LPVGYFERSIFDKNteFKKNRYKDVPCNDKTRVIlkdgypgDYVHANYVKGTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYF
... .. ... .| ..||||||....| .||. ||..|.|..| .. ||.|||||..|. | |||. ..|. .|.||.||.|.|| ||..|.
gipseitpalylgn..ldknRykdilpydhsrVk.......dYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqyw
PDteGQVLTFGEITVTCTESTTPdNHTQLKMLTVMDK----KSGKSHKLYHYKIITWPDKSIALSN-----LAILRTLRSLRK--------------MPG
|. |..||.|..|||... .. .. | .|.| . ....|....|.....||| .. .. | .|. .|. .| .|
pe..ggsltygdftvtllseevl.ddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsgg
PIVVHCSAGIGRTGTFAAIEVGAQCLlnGKAFRPADLVRAVRHCRLN-SVQMDTQYLMLVEAILDLG
|..||||||.|||||..|. ..| .. . . . |. .| .| . .||. || | |..|.|
pvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllell
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 137-330 | 7.7e-25 | 82.5 | In-house | 34-249 (418) | alignment | ||
Range on Protein: 137-330
Range on HMM: 34-249/418.0
VGYFERSIFDKNTEFKKNRYKDVPCNDKTRVILK---DGYPGDYVHANYVKGTKP-MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEP
|| | | ||. . |||| .. ..||| || | ||. |||. |. | || ||||| .| |.|||| .. . | || || | ||.
vgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgaypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdr
YFPDTEG--QVLT-------FGEITVTCTESTtPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLR-----KMP-----GPI
|.|. | |. || .| | | .. . |... . .|. |||. | . . |.|. .| ||
ywpeqiggeqfsiygngnevfgtysvelvevi.qdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpi
VVHCSAGIGRTGTFAAI
.||||||.||||||..
ivhcsagvgrtgtfcta
|
|||||||||
DSPc_SM00195 | 140-376 | 8.7e-73 | 240.2 | In-house | 18-261 (263) | alignment | |||
Range on Protein: 140-376
Range on HMM: 18-261/263.0
FERSIFDKNTefKKNRYKDVPCNDKTRVILKDG---YPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYF
.. ....||. .|||||.....|.|||.||. . ||..|||.||. | .|.|||||..| | ||||..|.| |.||.| |||. ||. |.
tteaekkknk..sknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdryw
PDTEGQVLTFGEITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM----PGPIVVHCSAGIGRTGTFAAI
|...|. |||.|.|...| .. .....|. |.. .. ...|...|.. .|||... |. .|. ||...| ||||||||||.||||||..|
peesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvti
EVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
.. . | ..| . ..|...|. | ..||...|||...||||..
diilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
PTPc_SM00194 | 140-376 | 8.7e-73 | 240.2 | In-house | 18-261 (263) | alignment | |||
Range on Protein: 140-376
Range on HMM: 18-261/263.0
FERSIFDKNTefKKNRYKDVPCNDKTRVILKDG---YPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYF
.. ....||. .|||||.....|.|||.||. . ||..|||.||. | .|.|||||..| | ||||..|.| |.||.| |||. ||. |.
tteaekkknk..sknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdryw
PDTEGQVLTFGEITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM----PGPIVVHCSAGIGRTGTFAAI
|...|. |||.|.|...| .. .....|. |.. .. ...|...|.. .|||... |. .|. ||...| ||||||||||.||||||..|
peesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvti
EVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
.. . | ..| . ..|...|. | ..||...|||...||||..
diilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeailey
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 143-376 | 5.6e-66 | 218.0 | In-house | 4-245 (249) | alignment | ||
Range on Protein: 143-376
Range on HMM: 4-245/249.0
SIFDKNTEFKKNRYKDVPCNDKTRVIL---KDGYPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDt
|.. . .||||.|....| .||.| ......||..|.|..|. |. ||.|||||..| | |||. ..|. .|.||..| |.|| ||..|.|.
svallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.
eGQVLTFGEITVTCTESTTpDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK------MPGPIVVHCSAGIGRTGTFAAIE
|..|..|..|||... .. .. . .|.. ... |.|.. .|. .. ||| .. | .|. .. .|| .||..||||||.||||||.|.
.ggsleygdftvtllsvev.kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaay
VGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
..| . . . . |. .|..| ..||.. || | ||.|.|
lmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 143-384 | 4.7e-49 | 161.5 | In-house | 30-276 (281) | alignment | ||
Range on Protein: 143-384
Range on HMM: 30-276/281.0
SIFDKNTEFKKNRYKDVPCNDKTRVILKDGYP----GDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPD
..|.. . ||||| ..|| | .|| || | ||.||||.. | .|||||| |.| |.|||. || .|| |||...| | || |||
tvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfpr
TEGQVLTFGEITVTCTESTTPDNHTQLKmltVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQC
.| | ...|. .|| . . |... . |. ||| . | .|. || .| | |.|||||.||.||. |.|. |
nahcclqfdklsvsyedstvnkslvttr...lnlsyegetrlithwlwkewpdwqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqs
LLNgkAFRPADLVRAVRHCRL----NSVQMDTQYLMLVEAILDLGVAFKYIE
. . | |. . | | |. ||| ||... . .||.|||.| |
ihs..hftlpdikqivshlrvtgraasvqtlqqymliwkvlldfgvaykqit
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 143-375 | 3.7e-41 | 135.8 | In-house | 36-274 (515) | alignment | ||
Range on Protein: 143-375
Range on HMM: 36-274/515.0
SIFDKNTEFKKNRYKDVPCNDKTRVIL---KDGYPGDYVHANYVKGTKP--MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDT
.. ... .|||||||.. |..||.| .| ||. | |... . .| .|||.| . | ||.|||| |..| |. .| |. . || |.||
tvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdk
EGQVLTFGEITVTCTeSTTPDNHTQLKMLTVMdkKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSL----RKMPGPIVVHCSAGIGRTGTFAAIEVG
|. . ||.| | |. . . . |||. |. .|. . .. |||| . ..|. .. . .. |...|||||.|||| . .|.
pgdsvkfGsikvelv.sleactggikrkltvl..kgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsv
AQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
.... ..|. .| | || . || .. .|.|.
vahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavle
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 143-376 | 1.1e-39 | 131.3 | In-house | 44-283 (297) | alignment | ||
Range on Protein: 143-376
Range on HMM: 44-283/297.0
SIFDKNTEFKKNRYKDVPCNDKTRVILKDGY---PGDYVHANYVKGTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRpKCEPYFPDTeg
.|. .|.|.|||.. |. ||.|. ||| | .||| | .| || | |.| | |.|||.| |..| || .. |. . || |..|.
tvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkhrlittqmPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdk..
QVLTFGEITVTcTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIAL--SNLAILRTLRSLRK-----MPGPIVVHCSAGIGRTGTFAAIEV
| |||...|. ..|.. . . |.| |. . . . |. . ||||.. | ..| . .|| ||..|||.||.|||| . .|.
gvttfGdvsvv.llsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltids
GAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
. |. .||. .|. | . || . || .. .|.|.
vvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlea
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 143-375 | 5.9e-34 | 112.3 | In-house | 41-277 (439) | alignment | ||
Range on Protein: 143-375
Range on HMM: 41-277/439.0
SIFDKNTEFKKNRYKDVPCNDKTRVIL--KDGYP-GDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRpkcepYFPdT
|. .. . ||||||| | |||.| | | |. |||.|| .. ..| |||| |.|. | ||.|... .. | ||..|.| . |.| .
slaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywp.s
EGQVlTFGEITVTCTESTTPDNHTqLKMLTVMDKK--SGKSHKLYHYKIITWPDKSIALSNLAILRTLRSL-----RKMPGPIVVHCSAGIGRTGTFAAI
...| .|.|.| . |.. .. . |.... . | . . ... |.|||| . .| ||.. .. ||.|||||||.||||| |.
daev.cygdiavrvdrnielpnyv.irgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiial
EVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
.. . | . .|. .|. | . || ||... .|.|.
dialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 143-374 | 9.7e-32 | 106.3 | In-house | 39-277 (314) | alignment | ||
Range on Protein: 143-374
Range on HMM: 39-277/314.0
SIFDKNTEFKKNRYKDVPCNDkTRVILkDGYP---GDYVHANYVKGTkPMFILTQGPLKDTAMDI----------WRMVL--QEGVAAICM---------
..|. .||||.|... | .|||| .|.| || .|.||.| || |||||. | |. ||||| . | | |
lvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf.lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevlade
------------LCELIENGrpkcepyfpdtegQ--------VLTfgeitvtctesttpdnhtqlkmlTVMDKKSGKSHKLYHYKIITWPDkSIALSNLA
|..| .|| | .... .. .. ..|. | .|| | .
lsrLdaAlgKtpllildgng.............neptaadlellk.......................eelydpelferlgikylripvpD.gsaplled
ILRTLRSLRK--MPGPIVVHCSAGIGRTGTFAAIEVgaqCLLNGKAfRPADLVRAVRHCRL-----NSVQMDTQYLMLVEAIL
... |. ... .||..|||.||.||||||... ... . ... .. || .| ..... ||.. ||.|
fdeflefieeadkggpvlvHCkaGkgRtgtfvvaay...lmkllgv.sleealedvrlkRpinpnpgfieqleqyefileall
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 143-375 | 1.6e-26 | 87.9 | In-house | 28-257 (267) | alignment | ||
Range on Protein: 143-375
Range on HMM: 28-257/267.0
SIFDKNTEFkkNRYKDVPCNDKTRVILKDGYpGDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKcepYFPDTEGQ
|| || |. ||. |. |.|||||.. .|. | ||.| || .||.||.||| | | . .. ...|. | .| .. .. ..| ||
siaeknqer..nrlddnlpyddtrvilrtke.eeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvftdnirl...fwPPkmgq
VLTFGEITVTCTESTTpDNHTQLKMLTV-MDKKSGKSHKLYHYKII--TWPDKSIaLSNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCL
. ..|| . .| |. | . . ..| . ||.|| .| | | . . | . |.||.||.|.||.||| |. . .
akkyqdltvehsleke.endyqiitlelkfknesahnvtlyyykkwnintnnkpy.lkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqlera
LNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. |..| .|. | |. .|. . | . .
ktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 143-375 | 4e-26 | 86.3 | In-house | 38-234 (392) | alignment | ||
Range on Protein: 143-375
Range on HMM: 38-234/392.0
SIFDKNTEFKKNRYKDVPCNDKTRVIL---KDGYPGDYVHANYVKGTKP--MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGrpkcepyfpdt
.. |. . ||||||.. |..||.| | ||. | |... . .| .||| . |.||||.|| |..|.|. .| |
tvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd...........
egqvltfgeitvtctesttpdnhtqlkmltvmdkKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM----PGPIVVHCSAGIGRTGTFAAIEVG
| . . ... |||| . ..|. .. .. |...|||||.|||| .|.
..................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsv
AQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. . ..| .|. | || . || .. |.|.
vahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavle
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 143-290 | 1.2e-12 | 42.0 | In-house | 90-233 (244) | alignment | ||
Range on Protein: 143-290
Range on HMM: 90-233/244.0
SIFDKNTEFKKNRYKDVPCnDKTRVILKDGYPG-DYVHANYVK--GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENgrpkcEPYFPDTEG
|. | .|. .| | || | | | |. | .| | .|||| || ||.||.|.|.|. | . .| . |. . |.||.|
dafnpnnswknregaglpf.dfnrvplskgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpdsep
QVLTFGEITVTCTESTTPDNHTQLKmLTVmDKKSGKSH-KLYHYKIITWPDK
.|||| |. | . | . . .|| | ..| ||
lewyeeditvtltdrdefknikasn.lei.esdmneshqaltmfqisnwpsd
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 144-377 | 1.6e-56 | 186.3 | In-house | 42-287 (305) | alignment | ||
Range on Protein: 144-377
Range on HMM: 42-287/305.0
IFDKNTEFKKNRYKDVPCNDKTRVILKDGYPGDYVHANYVKG-TK-PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQV
| . | .||||||| | |. || |. .| .|.||||| |. || || ||..| |.| | ||. | || |||.|.| | || ||. ...|
afkeaqeagknrykdvgcldnnrvklegpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdv
LTFGE----ITVTCTESTTPD----NHTQLK-MLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEV
|.| | |.| . |.| . ..... |.. .|..| ||. | |||. . ..|||| | | |||||||||||||||. .|
lefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmley
GAQCLLNGKAFRPAD-LVRAVRHCRLNSVQMDTQYLMLVEAILDLG
. ||.|. .| ... .| | ||.| |.|||.. . ||.
ildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 144-376 | 3.3e-53 | 175.4 | In-house | 34-276 (290) | alignment | ||
Range on Protein: 144-376
Range on HMM: 34-276/290.0
IFDKNTEFKKNRYKDVPCNDKTRVILKDGYP---GDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTE
.|... |||||||. ||.|| |. ||. ||..||. | ..| .|||| .| | |||. . | . |.|...|.|. ||| |.|..
agekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeeg
GQVLTFGEITVTCTESTTPDNHTQLKMLTVMDKksGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM----PGPIVVHCSAGIGRTGTFAAIEVGA
.. |.|||..||..| . |. ...|.| . ..|.|.| .. |||. . | .|. ....|.. |.|||||||.||||| ||.
eeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvr
QCLLNGKA---FRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
. | ..| . |||. .|. | || || .. .|...|
ellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavael
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 144-376 | 1.1e-47 | 157.7 | In-house | 40-282 (305) | alignment | ||
Range on Protein: 144-376
Range on HMM: 40-282/305.0
IFDKNTEFKKNRYKDVPCNDKTRVILKD--GYP-GDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTE
. |... .|||.|.. |. |.||. . ||. |.||.| | .|..|||||.| | ||....| | | ||..|.|.|. ||. |.|...
vgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesk
GQVLTFGEITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK--MPG---PIVVHCSAGIGRTGTFAAIEVG
... |||..|. ....| .... |. ..... .|. . .|.. .|||. . . ..|. .. ..| . . |..||||||.||||.| |...
tekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdia
AQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
. | . . .......|. |.. || || | .|. .|
lerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldel
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 144-374 | 1.8e-46 | 153.3 | In-house | 14-261 (270) | alignment | ||
Range on Protein: 144-374
Range on HMM: 14-261/270.0
IFDKNTEFKKNRYKDVPCNDKTRVILKDG---YPGDYVHANYVK---GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDT
. . .. | |||.|. . .|||.|.. |. ||||. | | .| ..|||. | . |||...| | || |. .| |.|| ||| |.|
lpeaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpae
EGQ--VLTFGEITVtCTESTTPDNHTQLKMLTVMdkKSGKSHKLYHYKIITWPDKSIALSNL---------AILRTLRSLRKMP---GPIVVHCSAGIGR
.. |..|.|.| ...|.. .. |. |.. ..|....| |. ||||... .. ..||..| .| .|..||||||.||
pkekvkledgkikv.lalseekeegyiltrlrle..ekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgR
TGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAIL
|||. |.. . ..| . | .. .....|. | . || || .| .|..
tGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavv
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 144-373 | 5.2e-23 | 75.9 | In-house | 47-281 (302) | alignment | ||
Range on Protein: 144-373
Range on HMM: 47-281/302.0
IFDKNTefKKNRYKDVPCNDKTRVILKdGYPGDYVHANYVKGT--KPMFILTQGPLKDTA---MDIWRMVLQEGVAAICMLCELIENGRpKCEPYFPDTE
.| ||. |||. .|||. |...|.|. . | .||.| |. .. ||.| | .|.. . |||| || .. . .| | . . .|| .
afkknl..kknqsedvpildsnlvkle.aepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkks
GQVLTFGEITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSL----RKMPGPIVVHCSAGIGRTGTFAAIEVGA
|. ...|.. | ..... .. |. . | | . |..|.. . .. .| .. | ..|. |.|| |.| . |
gdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSknGaGRagafltlavav
QCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAI
..| .||. . ...|...| | ..|. .|| .| |.
eklqkgkepnikeivksiRsqRpravdslkQyvslyial
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 145-376 | 5.1e-42 | 138.8 | In-house | 32-269 (285) | alignment | ||
Range on Protein: 145-376
Range on HMM: 32-269/285.0
FDKNTEfkKNRYKDVPCNDKTRVILKDgYPGDYVHANYVKG---TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQV
.. | . ||| || | ..|||.||. . ||.||.... . .| ||||| .| |.|.|. || .| . ||| |.| | || |.|. |.|
yeanpd..lnryadvrcieetrvvlkn.hdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgev
LTFGEITVTCTESTTP-DNHTQLKMLTVMDKKSGKSHKLY--HYKIITWPDKSIALSNLAILRTLRSLRK---MPGPIVVHCSAGIGRTGTFAAIEVGAQ
. ||. .| || | |. |||.. . | || | .. |||. .. . ..| ||.||||||.||| || |. .
vkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyati
CLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
... |.|| .| |...|| |.|.| ...
rimenpniemldivremramrfqavqshmqflflyvvlmey
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 145-376 | 5.6e-42 | 138.8 | In-house | 53-294 (330) | alignment | ||
Range on Protein: 145-376
Range on HMM: 53-294/330.0
FDKNTEFKKNRYKDVPCNDKTRVIL--KDGYP-GDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDtEG
.|. . .|||. .. .| .|||| |.| . ||. | ...| | || .|||...| | |||. . |.| || || | . ||. |.|| ||
askeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywPd.eG
qVLTFGEITVTCTESTTPDNHTQLKMLTV--MDKK-SGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK----MPGPIVVHCSAGIGRTGTFAAIEV
..|.|.|.|. ..| . | |.| |.. || . .. .||| . .|. |. ..| . ||||||||||.|||||| ...
.lvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivlda
GAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
. . . . |. .| | . || | || .. ...|.
vlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlley
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 146-376 | 1.5e-52 | 173.5 | In-house | 47-284 (293) | alignment | ||
Range on Protein: 146-376
Range on HMM: 47-284/293.0
DKNTEFKKNRYKDVPCNDKTRVIL---KDGYPGDYVHANYVKGTKP--MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQ
..... .||||... |..|| | || ||. |||..| . || ||||| .| |.||||... . .| || .|.|.|. ||| |.|..| .
elavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeep
VlTFGEITVTCTESTTPDNHTQlKMLTVMDkkSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMP------GPIVVHCSAGIGRTGTFAAIEVGA
| ..|.|.|| ..... .... . |.. . ...|. .|. ..||| . . ..|. .| .|.. .|||||||||.|||||| |..
v.lyGdikvtlvaeeeledwvi.relkiek..ekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrll
QCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
| . . . .| ..|. | . || .||... ...|||
qaieeedyvdifgivaelReeRnllvqtekqYifihqcvldl
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 146-375 | 2.4e-52 | 173.4 | In-house | 44-279 (564) | alignment | ||
Range on Protein: 146-375
Range on HMM: 44-279/564.0
DKNTEFKKNRYKDVPCNDKTRVILKD--GY-PGDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTeGq
.|.. .||||... |..||.|. | ||. |....| .. .| |||||..| .| |||| .. .. | || .| |.|. ||. |.|.. |
nkpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.
VLTFGEITVTCTESTTPDNhTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM----PGPIVVHCSAGIGRTGTFAAIEVGAQC
|.||.||| .|... . ... ... .||| .|.. ... . |||. . | ..|. .| |.. ||||||||||.|||||| .|.. .
tetygeltVtleeeeelad.yeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamler
LLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. . | |.|.|. | || .|| . ||||.
ikeektvDiyqyvkalrkqRnamVqteeQYiFiheaile
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 146-375 | 9.8e-44 | 144.4 | In-house | 39-275 (314) | alignment | ||
Range on Protein: 146-375
Range on HMM: 39-275/314.0
DKNTEFKKNRYKDVPCNDKTRVILK--DGY-PGDYVHANYVKGTK--PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTeGQ
|. . .|||..|. |..||.|. || ||. |... . | || |||||..| | ||.|..|. |.| || ||.|.|| || |.|. ..
kkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPed.te
VltFGEITVTCTEStTPDNHTQLKMLTVMD--KKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM----PGPIVVHCSAGIGRTGTFAAIEVGA
| .|.| |.. |. .... ....| .. . ... ... ..||| . |. ..|. .| . |. |.|||||||| |||||| ||..
v..ygdikvelvet.ellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivl
QCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. . . . |...| . | |. || .. ..||.
dmieregvvdvfnavktlrsrkvnmveteeqykfiydvile
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 146-380 | 1.5e-43 | 143.8 | In-house | 5-245 (250) | alignment | ||
Range on Protein: 146-380
Range on HMM: 5-245/250.0
DKNTEFKKNRYKDVPCNDKTRVILKDGY---PGDYVHANYVKGTK--PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPkCEPYFPDTegQ
| . .|||| |. |..||.|. ||. | ...| . .|| |||||..| | |||||.| ...| || .| |... .. |.| .
kkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve..k
VLTFGEITVTCTESTTPDNHTQlKMLTVMDKKSGKSHKLYHYKIITWPDKSIA---LSNLAILRTLRSLRKM--PGPIVVHCSAGIGRTGTFAAIEVGAQ
..|..||. .. . . |. . | . .| .. . ... ..||||.. . |..|. ... .. .|..|.||||.||.|.| ||. .
aekyGdvtvsllskeefadytk.rklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavle
CLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVAF
| . | ......|. | ..|. .|| .. |.|| ...
rlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsv
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 146-378 | 5.3e-42 | 139.0 | In-house | 44-287 (307) | alignment | ||
Range on Protein: 146-378
Range on HMM: 44-287/307.0
DKNTEFKKNRYKDVPCNDKTRVILKDG---YPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTegQ
.|. ||||.|. |||||.|| ||. |...|| | || |.|. |. | |||. . | | || .| | | ||. |.|. .
ekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..d
VLTFGEITVTCTESTTPDNHTQLKMLTVMDKKSG----KSHKLYHYKIITWPDKSIALSNLAILRTLRSL----RKMPGPIVVHCSAGIGRTGTFAAIEV
.|.| |.. .. . ..... .. . |... .|.|. |. .|.| . . ..|. .. . .. .||||||||| ||.|.| |...
evqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvalds
GAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGV
| | . . . |. .|. | || || | |.||
llqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyss
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 146-373 | 4.7e-34 | 112.5 | In-house | 36-289 (301) | alignment | ||
Range on Protein: 146-373
Range on HMM: 36-289/301.0
DKNTEFKKNRYKDVPCNDKTRVILKDG-----YPGDYVHANYVKGTK--PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTE
.... . ||.|.. |. |.||| .|. |.|..|.. || .|||.| | .|.||...|| ...| |...| |. . ||| |.|..|
lseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnse
GQVLTFGEITVTCTEST-TPD---------------NHTQLKMLTVMDKKsgKSHKLYHYKIITWPDKSIALSNLAILRTL-----RSLRKMPGPIVVHC
. .||..||| .... || | ... | .| .|... .... ||. . .|. . | . ||.||||
aeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdk..sswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHC
SAGIGRTGTFAAIEVGA-QCLLNGkAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAI
|....|.|.. ....| || .| ....|||. . |. || .. ..|
SdtVsrsGvYcsvsiglEQckaeg.VVdvfqvtkavrrskpgaVtTLeqytsiydvi
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 146-293 | 1.9e-28 | 94.2 | In-house | 29-180 (297) | alignment | ||
Range on Protein: 146-293
Range on HMM: 29-180/297.0
DKNTEFKKNRYKDVPCNDKTRVILKDGYPG-DYVHANYVKG----TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQ
.|. ..||||.|. |.||| |. . .. ||. |.|| .. .||.||||..| | |..| ...| .| |...| |.|| || ||.|.....
krnsslrknryrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqe
VLTFGEITVTCTESTTPDnHTQL--KMLTVMDKksGKSHKLYHYKIITWPDKSIA
|. |.. | ||. . . .. |... . .| .. | . ..|||. .
rlkagdvvveflsstsde.fdrviltelqliyr..sesrvvrhvqflswpdhGvp
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 147-375 | 4.6e-55 | 181.5 | In-house | 38-273 (280) | alignment | ||
Range on Protein: 147-375
Range on HMM: 38-273/280.0
KNTEFKKNRYKDVPCNDKTRVILKDGYPgDYVHANYVKGTKPM------FILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDtEGQ
| . .||||.|. |.|||.||.. ||. ||||. | .| |||||..|| | |.|| .. . |.|| .|.|.|| || |.|. ...
kpenlsknryrdilpydatrvklkeset.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrvkChqyWPe.ted
VLTFGEITVTCTEStTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRT---LRSLR-KMPGPIVVHCSAGIGRTGTFAAIEVGAQC
|..||..|.|... .. |. |...||.. ...|. . . . |||... .. .|. .|.|| . |.|||||||||||| . ..|. .
eleygefsvkceke.detksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalal
LLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. . ... | |.|| .| | . || .|| .. ||||
ieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 147-375 | 2.3e-49 | 163.1 | In-house | 34-267 (273) | alignment | ||
Range on Protein: 147-375
Range on HMM: 34-267/273.0
KNTEFKKNRYKDVPCNDKTRVILKDGYPgdYVHANYVKG----TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVL
|. . .||||..| |.|||.|.| . |. |...| . .|..|||| .|. |.|.|| . . | |. |.|. ||. |.|..... |
kkenkdknryrnvlPydetrvklgdegg..yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchrywPesknkkl
TFGE-ITVTCTESTTPDNHTQlKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM---PGPIVVHCSAGIGRTGTFAAIEVGAQCLL
. . ..|. . . |. .. . |.| |..||.|... | . ..||| .. | . .|. .. .|.. |||||||||||||.||. .|.| . .
kvsnrlevellkvqkldgfvv.ralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglie
NGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. | | ..|| .|. | || . ||.. .|||.
rdkefdvkeivrklreqrqgvvqtkdqyifvykaile
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 147-376 | 3.2e-49 | 162.2 | In-house | 52-288 (305) | alignment | ||
Range on Protein: 147-376
Range on HMM: 52-288/305.0
KNTEFKKNRYKDVPCNDKTRVILKDGYPGDYVHANYVKGT---KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLT
. . ||||.||||.|.. | |.. | ||.||||| . || .|||| .| ..| ||.|. | | ||| .| |. || |.| . |. |.
adiaitknryqdvpcqdqsavkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekle
FG-EITVTCTESTTP---DNHTQLKMLTVMdKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLN
. | | . | |. |. .| . ... . | . |||. . .|. | | ..| ||||||||||||||| ||| . . .
lksgivvenvsgskpmerdaeiqitllnlt.ysgdqkmsvrhlqwtewpdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekiae
GKAFRP-ADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
| | .||.|.| | |.| | |||.. .|.
nkpcppmpelvkalrdqrafsiqndvqylfihrvmlny
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 147-375 | 3.8e-42 | 139.2 | In-house | 41-275 (315) | alignment | ||
Range on Protein: 147-375
Range on HMM: 41-275/315.0
KNTEFKKNRYKDVPCNDKTRVIL---KDGYPGDYVHANYVKGTKP--MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQV
.. .|||||||.. |..||.| | ||. | |.|. . .| .||||| . | ||||||| |..| |. .. |. . || |.|| ...
etinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkads
LTFGEITVTCTESTTPDNHTQLKMltVMdKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLR----KMPGPIVVHCSAGIGRTGTFAAIEVGAQCL
||.| |. . . . .. |. |. .|| .|... .. |||| . ..|. .. .. | ...||||||.|||| . .|. . .
vefGsikvellsleadtdgvarkl..vt.rkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqi
LNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
.... ..|. .| | || . .| .. .|.|.
krtrsvdvfnfvknlrakrpylvqteeeyafiydavle
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 147-376 | 5.8e-41 | 135.4 | In-house | 46-278 (315) | alignment | ||
Range on Protein: 147-376
Range on HMM: 46-278/315.0
KNTEFKKNRYKDVPCNDKTRVIL---KDGYPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTegqV
| . .|||| .. ||.|| | . ||| ||...| | ..| .|||. . | ||.| .| .. | || .|.|. . |.| |.||
kienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk...k
LTFGEITVTCTESTTPDNHTQLKMlTVMDKKsgKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK----MPGPIVVHCSAGIGRTGTFAAIEVGAQCL
...|.|||| . .. | . .|. .. . .... ... .||| .. . .... | .. |.||||||||.|||||| ... . .
viyGkitvtrkseevnteytvrtl.svvfgd..nirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqa
LNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
.| .... ||. | . ||. || .. .|.|.
eaenaidvynfitgvrqnrikmvqvaeqyqfiydallet
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 147-375 | 2.6e-39 | 129.8 | In-house | 30-264 (283) | alignment | ||
Range on Protein: 147-375
Range on HMM: 30-264/283.0
KNTEFKKNRYKDVPCNDKTRVILKDGYPgDYVHANYVK-----GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDtEGQv
. . .|||.... |. || || . ||. | .. . .| .|.||..| .| |.|| .| ..|| || .| |. | || |.| .|
adenkrknrnqeivpadqwrvelksesr.dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPk.rGs.
LTFGEITVTCTESTTPDNhTQLKMLTVMDKKSGKSHKL-YHYKIITWpdksIALSNLAILRTL------RSL--RKMPGPIVVHCSAGIGRTGTFAAIEV
.|| ||| . || . | |.. . | || | ||..| | . .. ||. .| .|| .. ||||||||.|||||..| |. .
edyGeftvtlrkettsns.fiikelllrvnssakstlllahyqvidW....leygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasa
GAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. .| |. .| | || || .. |..|.
svkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvle
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 147-368 | 3.7e-27 | 89.8 | In-house | 53-283 (297) | alignment | ||
Range on Protein: 147-368
Range on HMM: 53-283/297.0
KNTEFKKNRYKDVPCNDKTRVILKDG---YPGDYVHANYVKGT---KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQ
.. ||||.|.| |..|| ||. ||. | . . .|..| ||||| .| |.|.|| ..||. | .|..| |.| .|. |.||. .
aeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpdeGse
VLTFGEITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYkiITWPDKSIALSNLAILRTLR----SLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQC
| . |. . . | . | .... .. .|. ..||.... | ..| | | | |||||||.| ||||.. .|.. .
vyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhf..lswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnr
LLNGkaFRPADLVRAVRHCR---LNSVQMDTQYLM
||.| . |.. .. | | . |. |. .
llkG..vkeidiaatlehlrdqrpglvktkdqfef
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 147-375 | 2.2e-24 | 80.6 | In-house | 39-288 (296) | alignment | ||
Range on Protein: 147-375
Range on HMM: 39-288/296.0
KNTEFKKNRYKDVPCNDKTRVILKD--G-YPGDYVHANYVKG-TK-PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRpKCEPYFPDTEgqV
... .|||. .| |..||.|. | ||. | || . .| .| |..| |.| . ||.| .|.. |. .|.. . . .. |.| .
rkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks..k
LTFGEITVTCTESTTPDNHTQlKMLTVMDK----------KSGKSHKLYHYKIITWPD-KSIALS---NLAILRTLRSLRKMP------GPIVVHCSAGI
.||| | .|. . | .. ... .. | . . . .... .|. ... || . ..| |..|. ||.||..| |
eqygeifveiveekqyanlki.rtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGa
GRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
.|.| . ||.. . . . . . . |. .|. | . |.. ..| . . .|.
sRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlle
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 148-375 | 4.7e-61 | 201.7 | In-house | 8-240 (243) | alignment | ||
Range on Protein: 148-375
Range on HMM: 8-240/243.0
NTEFKKNRYKDVPCNDKTRVILKDgypGDYVHANYVKGTkPMFILTQGPLKDTAMD----IWRMVLQEGVAAICMLCELIENGRPKCEPYFPdteGQVlT
.||||.|....| .||.|.. .||..||....| | .|.|||||..| | |||. ..|. .|.||.||.|.|| ||..|.| |.| |
penlsknrysdilpydhsrvkleg...sdyinanliyvt.prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp...gev.t
FGEITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM------------PGPIVVHCSAGIGRTGTFAAIE
.|..|||...... |. |. ..| .. . .. .. .|| . ||| .. | .|. |. .|. ||..||||||.|||||..|.
ygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaay
VGAQCLlngKaFRPADLVRAVRHCRLN-SVQMDTQYLMLVEAILD
. ..| . . . . |. .| .| . .|| || | ||.|
lmllll...g.vdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 148-373 | 1.2e-45 | 150.7 | In-house | 26-264 (274) | alignment | ||
Range on Protein: 148-373
Range on HMM: 26-264/274.0
NTEFKKNRYKDVPCNDKTRVILKDGY----PGDYVHANYVKGTK---PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQ
. .|||||.. |...||.|. .|. |||.|| . ... ||||| | .| |||. || | | || .| |. . ||. ||||.|.
fgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedy
--VLTFGEITVTCTESTTpDNHTQLKMLTVMDKKSgkSHKLYHYKIITWPDKSIALSNLAILRTLRS------LRKMP-GPIVVHCSAGIGRTGTFAAIE
..|.. .. .. .. |. ... |.. .. .....|| |||. . ..|.... .... .|.|||||||||||| | ||.
eiserygdveikvekive.rndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiais
VGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAI
.. . | . . .| .| | || . || .. .|.
iavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihral
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 148-375 | 2.9e-45 | 149.5 | In-house | 39-274 (281) | alignment | ||
Range on Protein: 148-375
Range on HMM: 39-274/281.0
NTEFKKNRYKDVPCNDKTRVIL---KDGYPGDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEgQVL
. .||||... |.||| . .. ||. ||.|.| . .| ||||. .. .. |.||... | || |. . ||.|. || |.|| . . |
denvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddn.sel
TFGEITVTCTESTTPDNHTQlKMLTVmDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSL---RK--MPGPIVVHCSAGIGRTGTFAAIEVGAQCL
..|..||. |.... .. . . ... ...||.. .. . . ..|||. . . ..| . . .. |.|.|||||.|||||. |.. .. .
kygdvtvkstaeeekatyie.rkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkav
LN-GKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. . . ..|. .|. | || .|| . |.||
eaeleeldvkavvaelrkernlmvqtvvqyefvykavld
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 148-375 | 9.9e-44 | 144.3 | In-house | 41-278 (288) | alignment | ||
Range on Protein: 148-375
Range on HMM: 41-278/288.0
NTEFKKNRYKDVPCNDKTRVILKdGYPGDYVHANYVKG---TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTF
.. .|||..|. |..|| |. | ||. | .||. . | || ||.||. |. | |.|| .. . | || . | |.||.. |.| .|. .|
klyseknrsrdilPyDhnRvklr.gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkf
GEITVTCTESTTPDNHTQLKmLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTL---RS-----LRKMPGPIVVHCSAGIGRTGTFAAIEVGAQC
|...||. . .. ..| . . |.. ... . ... | .. .||. . | .|. | .| ||. |.|||||||.||||.|| . ..
gdlsvtlksvretethverv.lkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavre
LLNGKAFR-PADLVRAVRHCRLNSVQMDTQYLMLVEAILD
| .|. ..|. .|. | ..|| .|. .. ||.|
lekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavle
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 148-223 | 9.7e-08 | 25.9 | In-house | 35-120 (347) | alignment | ||
Range on Protein: 148-223
Range on HMM: 35-120/347.0
NTEFKKNRYKDVPCNDKTRVILKD--------GYPGDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELI
. . .||| ||| .|.|||.| . |. | ..| .. .|||| || || |.|.|| |. . . | |
ekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtifepi
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 149-375 | 2.6e-62 | 205.7 | In-house | 8-241 (245) | alignment | ||
Range on Protein: 149-375
Range on HMM: 8-241/245.0
TEFKKNRYKDVPCNDKTRVILKDGYP---GDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDteGQVLT
.||||.|....| |||.|.. . ||..|.||.| .| ||.|||||..| | |||. ..|. .|.||.|. |.||.||..|.|. |..||
enkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl..geslt
FGEITVTCTESTTpDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK-----MPGPIVVHCSAGIGRTGTFAAIEVGAQCLL
.|..|||... .. ... . |.| ......|.. .|| . ||| ... . .|. |. .|| .||..||||||.||||||.|. ...|
ygdftvtllseeh.lddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqle
NGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. . . . |. .| .| ..||.. || | ||.|.
kelgvsleeavkelrsqRpgavqtpsqyrflyealle
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 149-382 | 7.9e-46 | 151.6 | In-house | 45-285 (318) | alignment | ||
Range on Protein: 149-382
Range on HMM: 45-285/318.0
TEFKKNRYKDVPCNDKTRVILKD---GYPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTegQVLT
. .|||| .. |.||| |.. ||. |||. | | .| .|.|| .| | |||| . . | | || .. |.|. |.. |.|. . .
vnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPsk..gsrs
FGEITVTCTESTTPDNHTqLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMP-----GPIVVHCSAGIGRTGTFAAIEVGAQCLL
.|...|. .|... .... |. ..| ... .| . |.. .|||... | .| .|. .|. ||||||||||.||||.| |... . .
ygklvvelkeevelsdyv.lrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerik
NGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLGVAFKY
. . . |. .|. | || . || .. ...|. ...
aealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdt
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 149-375 | 7.2e-41 | 134.8 | In-house | 31-269 (290) | alignment | ||
Range on Protein: 149-375
Range on HMM: 31-269/290.0
TEFKKNRYKDVPCNDKTRVILKDGYPgDYVHANYVK--GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEG-QVLTFG
.. ..|||.|| |..|..|... ||. |. |. | .||||||| .|. |.|| .. |. || ...|... || |.| | . |..
enrnlnryrdvspydhsrikleradn.dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellle
EIT--VTCTESTTPDNHtQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLR------SLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCL
... |. . . ... ....| . ..|. ......|.. .|||| .. | | |. | || . || |.||||||||.|||. .. .
dtklkvkliseerksyy.tvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvli
LNGKAFRPAD---LVRAVRHCRLNSVQMDTQYLMLVEAILD
. . | . ..|. || .| | . |||.
ekkddlssvdikkvllelrkyrlGliqtadqlrfsylaile
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 149-373 | 1.4e-31 | 104.6 | In-house | 48-292 (300) | alignment | ||
Range on Protein: 149-373
Range on HMM: 48-292/300.0
TEFKKNRYKDVPCNDKTRVILKDG--YPGDYVHANYVK----GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDT--EGQ
. .|||.||| ...|| |. .|. | .| |.. .| .||||. | | |.|| ..||. | || | .|.|. |. |||.. . .
enaeknrfkdvlPyednrvelsptkenstgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkk
VLTFGEITVTCTESTTPDNHTqLKMLTVMDKKSGKSHKLYHYKIITWPDKSIAL---SNLAILRTLRSLRKM----------PGPIVVHCSAGIGRTGTF
..||. || |.. | . . |.. |.. ...| . . |||. . . | |. ..|.|. |..||||||.||||
tvefgkfkvttkfsedsdsvi.ttglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvl
AAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAI
.. ..| ... .. .|. | || .|| .. ...
ilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvl
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 149-375 | 1.5e-30 | 101.1 | In-house | 6-238 (239) | alignment | ||
Range on Protein: 149-375
Range on HMM: 6-238/239.0
TEFKKNRYKDVPCNDKTRVILKD---GYPGDYVHANYVK---GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVL
. |||| .. |..||.|. ||. |.|.. |. .| ||| .. .. |.|||. || . | || ||| . || |.||. .
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskyc
TFgEITVTCTESTTpDNhtQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK--MPG--PIVVHCSAGIGRTGTFAAIEVGAQCLL
. .|. || . | .. . . . . . .|.|.. |||| . |.| | . | .|| | |.|||||.||||.| |. .
nl.rvtlrktevfa.dy..iirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqak
NGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
. |. . |.|.| | || ||... |.|.
kqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 149-374 | 1.8e-30 | 100.9 | In-house | 7-238 (239) | alignment | ||
Range on Protein: 149-374
Range on HMM: 7-238/239.0
TEFKKNRYKDVPCNDKTRVILKD---GYPGDYVHANYVK---GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVL
. |||| .. |..||.|. ||. |.|.. |. .| ||| .. .. |.|||. || . | || ||| . || |.||. .
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstskyc
TFgEITVTCTESTTpDNhtQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRK--MPG--PIVVHCSAGIGRTGTFAAIEVGAQCLL
. .|. || . | .. . . . . . .|.|.. |||| . |.| | . | .|| | |.|||||.||||.| |. .
nl.rvtlrktevfa.dy..iirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqak
NGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAIL
. |. . |.|.| | || ||... |.|
kqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 150-374 | 2.9e-35 | 116.4 | In-house | 38-274 (287) | alignment | ||
Range on Protein: 150-374
Range on HMM: 38-274/287.0
EFKKNRYKDVPCNDKTRVILKD--GYPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTeGQVLTFG
. ||||| || |.|||.| . ||. |||| . . || .|||. | | ||.||.. .|.. .. .|..| || |.|. . . |
avkknryadvlPiddtrvllsaegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPmrvG
EITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSL-------R--KMPGPIVVHCSAGIGRTGTFAAIEVGAQC
.|. . . . . . | ..| .. ... . .....||||..| . ....| . | . ||.|||...||||.|.. |. | .
GysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsr
LLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAIL
|.. .| | .| | || |. .|.||.
ledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
subfamily_egg_pd | Subfamily egg | 150-404 | 1.1e-34 | 114.5 | In-house | 40-293 (307) | alignment | ||
Range on Protein: 150-404
Range on HMM: 40-293/307.0
EFKKNRYKDVPCNDKTRVILK---DGYPGDYVHANYVKGTKP--MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENgrPKCEPYFPDTEGQVLTF
. .| | | |.|.| .|| |. | .|..|||.||| |||.| |||.| | |||| || | | || |. .|| |.| .| . | .
nlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvt
--GEITVTCTES-TTPDNHTQLKMLTVMDKKSGKSHkLYHYKiITWPDKSIALSNLAILrtlRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGK
| . ... . ..| .. | .. . . . | |.. . | | | .| | ||.. |.||.. |. ...|. |||. || |
vpGslrienlkvdskadplfrvtklklvGgddeerf.lehwq.gdvnnssdvysplrvl...rklrnlskpvvvqdilGvskaatlvaieiallsllrGp
AFRpADLVRA---VRHCRLNSVQMDTQYLMLVEAILDLgvAFKYIEDPKSLDAieTYKRNVADYVE
.. . || .| | ||. .||.. .| . | | || |.| . ...|
itk.slvlravvflrlrrrlsvesvllylfvyrlvlff..frdvigsakeldv..dyerwleerse
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 150-238 | 1e-14 | 49.0 | In-house | 47-154 (350) | alignment | ||
Range on Protein: 150-238
Range on HMM: 47-154/350.0
EFKKNRYKDVPCNDKTRVILK-----------DGYPGDYVHANYVKGT------KPMF--ILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKC
| |||||.. ...||.|| . ||. |||.| | .| | | ||.||. | | ....|. .| | .| ...|... ||
lfaknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekc
EPYFPDTE
. |... .
yrYWqegs
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 151-374 | 6.3e-71 | 233.9 | Pfam-A | 2-234 (235) | alignment | ||
Range on Protein: 151-374
Range on HMM: 2-234/235.0
FKKNRYKDVPCNDKTRVIL-KDGYPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEI
.|||||||... ||||| | ... | ||..||||||. | .||.||||||.| | ||||.|| | .| ||..| |.|| ||..|.|..|.. ||.|.|
kkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
TVTCT-ESTTPDNHTQLKMLTVMDKKSGK-SHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMP----GPIVVHCSAGIGRTGTFAAIEVGAQCLLNGK
.|... .... .....|. |.. .||. . ....... . .|||... |. ..|...|...| ||.|||||||.||||||.|... ..| ...
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaee
AFRPADLVRAVRHCRLNSVQMDTQYLMLVEAIL
. ..|. .|..| ..|| .|| .|..|||
evdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 151-374 | 6.3e-71 | 233.9 | In-house | 2-234 (235) | alignment | ||
Range on Protein: 151-374
Range on HMM: 2-234/235.0
FKKNRYKDVPCNDKTRVIL-KDGYPGDYVHANYVKGT--KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEI
.|||||||... ||||| | ... | ||..||||||. | .||.||||||.| | ||||.|| | .| ||..| |.|| ||..|.|..|.. ||.|.|
kkknRykdilpydktrvklkgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeesltygdi
TVTCT-ESTTPDNHTQLKMLTVMDKKSGK-SHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMP----GPIVVHCSAGIGRTGTFAAIEVGAQCLLNGK
.|... .... .....|. |.. .||. . ....... . .|||... |. ..|...|...| ||.|||||||.||||||.|... ..| ...
kvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaee
AFRPADLVRAVRHCRLNSVQMDTQYLMLVEAIL
. ..|. .|..| ..|| .|| .|..|||
evdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 151-375 | 3e-42 | 139.5 | In-house | 47-281 (290) | alignment | ||
Range on Protein: 151-375
Range on HMM: 47-281/290.0
FKKNRYKDVPCNDKTRVILK--DGY---PGDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVlt
..||.... .| |..|. | . .|..| |.|| | .|.||||...|..| |... || |..| ||.. ||.|. || |.||.. .
kllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtka..
FGEITVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKS----IALSNLAILRTLRSLR-KMPGPIVVHCSAGIGRTGTFAAIEVGAQCLL
.||.... .. .| .. .. |. ....|..... .|.| .|... . . |.| . . | . ..||||||...||...| |.... .
ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkck
NGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
.... | .. .||| || .... .|
tegvidvfqvlksqRiqkpgsvqtvqqyqgifqivlt
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 151-375 | 6.8e-39 | 128.7 | In-house | 2-169 (182) | alignment | ||
Range on Protein: 151-375
Range on HMM: 2-169/182.0
FKKNRYKDVPCNDKTRvilkdgyPGDYVHANYVKGTKPM--FILTQGPLKDTAMDIWRMVLQEGVAAICMLCeliengrpkCEPYFPDTEgqvltfgeit
..||||.|....| .| . ||..||.. | | ||.|||||..| | .||. ..|. .| .|. .|.|.|. .
ldknrysdilpydhsr.......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywpell..........
vtctesttpdnhtqlkmltvmdkksgkSHKLYHYKIITWPDKSIALsNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCllngkAFRPADL
. ..|. . ||| .. .|. .. .. .||..||||||.|||||..|. . .. . . .
...........................erlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl.....gvsleea
VRAVRHCRLNSVQMDTQYLMLVEAILD
|. || .| ..|.. || .| |.|.
vklvrsrRpgmvitpnqyfflqlalle
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 152-376 | 4.7e-41 | 135.7 | In-house | 49-277 (287) | alignment | ||
Range on Protein: 152-376
Range on HMM: 49-277/287.0
KKNRYKDVPCNDKTRVILKdGYPGDYVHANYVKGTK--PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGqvLTFGEITV
.|||.... |. ||.|| | ||. | ...| | ||....|. .|| . |... .. | || |||.. || . .| |.|... ...|| ..
dknRltqilvpdnyrvllk.gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeyni
TCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKS----IALSNLAILRTLRSLRK-MPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFR
. .. .. .. .. |. ..|.|. ... |.| .|... . . | | . .. || ..||||||...||...| |.... . . .
ellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviD
PADLVRAVRHCRLNSVQMDTQYLMLVEAILDL
.... | . .||| .|| ......|
vfqvlksqriqkpgsvqtveqykfindivley
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 152-373 | 4.2e-39 | 129.1 | In-house | 52-278 (301) | alignment | ||
Range on Protein: 152-373
Range on HMM: 52-278/301.0
KKNRYKDVPCNDKTRV-ILKDGYpGDYVHANYVK--GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEIT
.|.||. |||. .| | ...|| .|||... | || ||||||.|. | | |. | | | ||.. .|. ||| |.| . .. | | .
dkhryptvPckPstavevivdGk.rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfk
VTC--TESTTPDNHTQlKMLTVMDK-KSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRP
.. .|. .. .. . | | | . ... . ||. .|.|. . | . . ..| ||||||||||||. .| . |. |. ... .
ikiknkelilnkkisk.rtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksekPivvhcsaGiGrsvafigteylareveadptiel
ADLVRAVRHCRLNSVQMDTQ-YLMLVEAI
.. .. .|. | |.||. .| | | . ..
tealkhlrehrwngvqtnsqlywmtlGtv
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 152-377 | 9.8e-38 | 124.6 | In-house | 44-276 (312) | alignment | ||
Range on Protein: 152-377
Range on HMM: 44-276/312.0
K-KNRYKDVPCNDKTRVILKdGYPGDYVHANYVK-GTKPM-FILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLT--FGE
| ||| .. | |. | | | |.|||.|| ||| |. |||||..|. .|...| | ..| .|| ..|.| || | | | |
kdlnrypniqcwdrgrftla.gdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhrv
ITVTCTESTT---PDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAF
| ||| .. ..| |. | .|. || ||. .|||. . | . || | ...| |.. |||||.|||||.| || .| .
yteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdkkpviahcsagvgrtgtlaliesmiaalrhprkq
RPADLVRAVRHCRLNSVQMDTQYLMLVEAILDLG
| .|. | ||.. ||.. . ..|..
nvkdsfvllrkdrarsvrvfpqyvyalrcvlefl
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 152-374 | 6.1e-36 | 118.8 | In-house | 5-236 (237) | alignment | ||
Range on Protein: 152-374
Range on HMM: 5-236/237.0
KKNRYKDVPCNDKTRVILKD-GYPGDYVHANYVK---GTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEgQVLTFGEI
|||| .. . |..||.|| | ||. |.|.| || .| .||||. . |.|.|| || . | || |||. . || |.|.|. | ..| .
iknrygnivaydhsrvvlkgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstd.qpaaygvl
TVTCTESTTPDNHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLR----K--MPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGK
||. . ..| .|... . . .. |.. .|||. . |.|| . . . || ..|||||.|||| | |. . . |
tvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekk
AFRPADLVRAVRHCRLNSVQMDTQYLMLVEAIL
. | .. | .| ||... ..||
vvdiynyvysieedrpyiiqtkdqyvfihqtil
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 152-375 | 5.7e-32 | 106.3 | In-house | 63-289 (319) | alignment | ||
Range on Protein: 152-375
Range on HMM: 63-289/319.0
KKNRYKDVPCNDKTRVILK--DGYP-GDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCeliengRPKCEPYFPDTEGQVLTFGE
|||. .. ||..| |. .| ||. | .|.| | ..| .||||..| | |||. . ...| .| . || |.| . ..
dknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfk
ITVTCTESTTPdnHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRT------LRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNG
. |. | | .. .. | | |. ... |||. . ..| |.| . . .||||||||.||||.. ...| . . .
vkvdsveetae..yvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkee
KAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
| ..|| .| | . || .|| .. |.|.
kqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 152-375 | 8.4e-32 | 105.8 | In-house | 27-253 (284) | alignment | ||
Range on Protein: 152-375
Range on HMM: 27-253/284.0
KKNRYKDVPCNDKTRVILK--DGYP-GDYVHANYVKG--TKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCeliengRPKCEPYFPDTEGQVLTFGE
|||. .. ||..| |. .| ||. | ...| | ..| |||||..| | |||. . ...| .| . || |.| . ..
dknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfk
ITVTCTESTTPdnHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRT------LRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNG
. |. | . .. .. | | . |. ... |||. .. ..| |.| . . .||||||||.||||.. ...| . . .
vkvdsveesee..yvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkee
KAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILD
| ..|| .| | . || .|| .. |.|.
kqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 153-396 | 3.3e-35 | 116.7 | In-house | 22-264 (290) | alignment | ||
Range on Protein: 153-396
Range on HMM: 22-264/290.0
KNRyKDVPCNDKTRVILKD---GYPGDYVHANYVKGTKP-MFILTQGPLKDT-------AMDIWRMVLQEGVAAICMLCELIENGRP----KCEPYFPDT
..| .|| .|||.||. . ||.|||.|. . .|||| |.... . | |. || | . |||| |. . |. |.|..
dqR.levpLveatrvvLkgygkrfnddyiHAnrvtcpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpes
EGQVLTFGEITVTCTESTTPDNHTQlKMLTV-MDKksGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQC
.|. |.|. .|| |.. . |. . . |.| |. .. ... |... | . .. ... .| .. ... |..||| || | ..|||..| |
vgeelkfkgltvkCkskekeddvet.Relvvkfdd..eeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQk
LL-NGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAILdlgvafkyiedpksLDAIETYK
. ... .|.. |.|. | . .. .... . .|. | |||...
iaetsgsvkledvlkalrkqralaitsalelafvdagiv..............llaievld
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 153-304 | 3.2e-16 | 53.9 | In-house | 31-188 (319) | alignment | ||
Range on Protein: 153-304
Range on HMM: 31-188/319.0
KNRYKDVPCNDKTRVILK---DGYPGDYVHANYVKGTK---PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQ--VLTF
|.|. .| .|||.|. | |..|.||.| . .| .| .|.|.. | ||.| . | |..| |.| .| |.| |. ..
ksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketldntsly
GEITVTCTESTTPDnHTQLKMLTVMDKKSGKSHKLYHYKIiTWPDKSIALSNLAILRTLR
|.| || . . | . . | . . .| .| || |.. . .. |.. |
Gdilvtlkgrevkd.ryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamll
|
|||||||||
subfamily_Cele-PTP-2_pd | Subfamily Cele-PTP-2 | 155-239 | 2.3e-06 | 19.4 | In-house | 50-135 (327) | alignment | ||
Range on Protein: 155-239
Range on HMM: 50-135/327.0
RYKDVPCNDKTRVILkdGYPGDYVHANYVKGTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCE---LIENGRPKCEPYFPDTEG
.| |. ||. | ... .||. .|. | | | .. |||..|.. . . || . || |||
vrlpipirdnrrvlc..gsdeeffpgqyvrmegaeyiivqaptkksskliwrvilkdhirilvclchdeqmsgsddgkcytyfptele
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 170-373 | 6.9e-34 | 112.5 | In-house | 7-169 (176) | alignment | ||
Range on Protein: 170-373
Range on HMM: 7-169/176.0
KDGYPGDYVHANYVKGTkpMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLtfgeitvtctesttpdnhtqlkmltvm
.... ||..||.. | ..| ||||| .| .| ..|....|. |. .|.|..| || || |.|. |. .
gldldldyinanlilgs..rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...........................
dkksgkshklyHYKIITWPDKSIALSnLAILRTLRSLRKMP---GPIVVHCSAGIGRTGTFAAIEvgaqCLLNGKAFRPADLVRAVRHCRL-NSVQMDTQ
.|. . ||| .. . ..|. |. .|.. ||..||||||||||||..|. | .| . . . .. || .| ..|| . |
...........qylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQ
YLMLVEAI
| .| |..
yrflyefe
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 173-372 | 4e-26 | 87.2 | In-house | 16-166 (178) | alignment | ||
Range on Protein: 173-372
Range on HMM: 16-166/178.0
YPGDYVHANYVKGTkpmFILTQGPLkdtaMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGqvltfgeitvtctesttpdnhtqlkmltvmdkk
.|| .|... . ..|.. | | .... ..|. .|..|.| .|.|..|| ||.|. .|
ersdyinaseilpg...lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag.................................
sgkshklYHYKIITWPDKSIALSNLAILRTLRSLR----KMPGPIVVHCSAGIGRTGTFAAIEVGAQCllngkAFRPADLVRAVRHCRLnSVQMDTQYLM
..|. | .|| . . .|.... .. . .||..||||||.||.||..|. .. . . . .. || .| |. . |.
.......iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnpgqlrq
LVEA
| |
Lyef
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 175-377 | 1.4e-40 | 135.0 | In-house | 4-225 (272) | alignment | ||
Range on Protein: 175-377
Range on HMM: 4-225/272.0
GDYVHANYVKGTkPM------FILTQGPLKDTAMDIWRMvLQEGVAAICMLCELIENGRPKCEPYFP----------DTEGQVLTFGEITVTCTESTTPD
..|..|..|.| .....|||. || |.||. ..|. .|..|... | || ||..| | |.. . ..| ..||... .. .
sgyiNardvggy.grvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
NHTQLKMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNlaILRTLRSLRKmPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFR--------PADLVR
... ..| .. . |......|. . ||| ... . .|. |. |.. .||..||||||..||||..|. .. . . ... |.
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeave
AVRHCRLNSVQMDTQYLMLVEAILDLG
.| .| ..|| ..|||.| ||.|.|
elraqrpgavqteeqylflyeallell
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 175-370 | 1.5e-31 | 104.8 | In-house | 2-163 (174) | alignment | ||
Range on Protein: 175-370
Range on HMM: 2-163/174.0
GDYVHANYVKGTK--PMFILTQGPLKdtamdIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDtegqvltfgeitvtctesttpdnhtqlkmltvmdKK
|| .|...... | .|..||||. |.|. ..|. .. ||.|..|.|. || |.|. ..
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..................................lr
SGKSHKLYHYKIITWPDKSIALSNLaILRTLRSLRKM-----PGPIVVHCSAGIGRTGTFAAIEVGAQCLLnGKAFRPADLVRAVRHCRLNSVQMDTQYL
. .. ..|. . ||| . .. .|. .. ... ||..||||||.|||||..|. ..|| .. ||||..| .| ..||.. ||
edlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyr
MLV
|
fly
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 175-370 | 9.4e-31 | 102.2 | In-house | 5-154 (172) | alignment | ||
Range on Protein: 175-370
Range on HMM: 5-154/172.0
GDYVHANYVKGTKPM--FILTQGPLKDTAMDIWRMVLQEGVAAICMLCELiengrpkcepyfpdtegqvltfgeitvtctesttpdnhtqlkmltvMDKK
||..|.|.... . || ||||| | | |||. ..|. .| .|.|| . .
sdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..............................................lydp
SGKSHKLYHYKIITWPDKSIAlSNLAILRTLRSLRK-----MPGPIVVHCSAGIGRTGTFAAIEVGAqcllngKAFRPADLVRAVRHCRLNSVQMDTQYL
.. .. ..| . ||| . . .|..|. ... ||..||||||.|||||..|. . . . . |. ||..| ..|| . ||
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
MLV
|
fly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 176-371 | 8.8e-28 | 92.2 | In-house | 4-147 (151) | alignment | ||
Range on Protein: 176-371
Range on HMM: 4-147/151.0
DYVHANYVKGTkpmFILTQGPLKdtamDIWRMVLQEGVAAICMLCELIENGrpKCEPYFPDTEgqvltfgeitvtctesttpdnhtqlkmltvmdkksgk
|| ...|| | .....||| | .... ..|. .|..|... |.| .| |.|...
dyinfsyvtgg...lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.....................................
sHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM-PGPIVVHCSAGIGRTGTFAAIEVGAQCllngkaFRPADLVRAVRHCRLNSVQMDTQYLMLVE
....|. |. ||| .. || |.|. |. |... .||..||||||.|||||..|. .. . ... .. .| .| ..|| .|.|..
.ievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlf
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 178-290 | 1.6e-08 | 28.9 | In-house | 16-124 (130) | alignment | ||
Range on Protein: 178-290
Range on HMM: 16-124/130.0
VHANYV--KGTKPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENgrpkcEPYFPDTEGQVLTFGEITVTCTESTTPDNHTQlKMLTVmDKKSGK
..|..| | ..||| || ||.||.|.|.|. | . .| . |. . |.||.| .|.|| |. .| . | . ... .
inasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivtltdrdefknika.snlei.esdlne
SH-KLYHYKIITWPDK
|| | ..| ||
shqaltmfqisnwpsd
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 187-289 | 4.7e-10 | 33.4 | In-house | 235-330 (440) | alignment | ||
Range on Protein: 187-289
Range on HMM: 235-330/440.0
KPMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENgrpKCEPYFPDtEGQVLTFGEITVTCTESttpDNHTQLKMLTVMDKKSGKSHKLYHYKIIT
| || || || | .|.||.| . ...| || .| .. | |.| . . .||| .|| | .| ..|. |. | . |.. ... |
knafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpv.ntrsvtfgpftvghkgs...enmnrvkvrtlelkykeevheirqfevqt
WPD
||
wpt
|
|||||||||
subfamily_eak_pd | Subfamily eak | 188-292 | 2.6e-13 | 44.1 | In-house | 93-194 (332) | alignment | ||
Range on Protein: 188-292
Range on HMM: 93-194/332.0
PMFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTEStTPDNHTQLKMLTVmdKKSGKSHKLYHYKIITW
.||| . .| . |.|||.. || .| | .|.. | . |||| ..| || . |.. | | . ..| . .| ..|...|||. |
rkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildverkef.vkrniletrllel..skGnethrvlhykvfGw
PDKSI
. ..
tettl
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 189-370 | 4.2e-29 | 96.6 | In-house | 10-143 (152) | alignment | ||
Range on Protein: 189-370
Range on HMM: 10-143/152.0
MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFpdtegqvltfgeitvtctesttpdnhtqlkmltvmdkksgkshklyHYKIITWP
.|| ||||. |. | |||. . |. .| ||.|| |.|..||| |. .|. . ||
efiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..............................................qylhlpwp
DKSIALSNLAILRTLRS----LRKMPGPIVVHCSAGIGRTGTFAAIEVGAqcllngKAFRPADLVRAVRHCRLNSVQMDTQYLMLV
| . . .| |. ... ||..||||||.|||||..|. . . . . |. || .| ..|. |. |
DhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 189-337 | 5e-23 | 76.3 | In-house | 39-181 (263) | alignment | ||
Range on Protein: 189-337
Range on HMM: 39-181/263.0
MFILtqgpLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTESTTpDNHT-QLKMLTVMDKkSGKSHKLYHYKIITW
...| | .| ..... | . . |||. |.|. ||. ||| . . . ...|..|.. | |..| .... | |.. ||. |
lysl....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs.dvllktlellstlge.KkkthtvkhysykgW
PDKSIALSNLAILRTLRSLRKMpGPIVVHCSAGIGRTGTFAAIEVGAQCL
..| ||. |. |. ..|||||.||||. |. .|. | .
iekndpelareilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkm
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 189-339 | 4.8e-16 | 53.5 | In-house | 5-163 (198) | alignment | ||
Range on Protein: 189-339
Range on HMM: 5-163/198.0
MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTEST-TPDNHTQLKMLTVMDKKSGKSHKLYHYKIITW
.| || ||..| |.|.|| . | | |. . | |.| || . .| ..||. | || .|| . .. ||.. .|
ryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
PDKSIALSNLAI--LRTLRSLR-----KMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLN
.|. | . . . | . . |..|||| | | || | |...| . .
kekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrshee
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 189-339 | 4.9e-16 | 53.5 | In-house | 6-164 (199) | alignment | ||
Range on Protein: 189-339
Range on HMM: 6-164/199.0
MFILTQGPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTEST-TPDNHTQLKMLTVMDKKSGKSHKLYHYKIITW
.| || ||..| |.|.|| . | | |. . | |.| || . .| ..||. | || .|| . .. ||.. .|
ryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftsw
PDKSIALSNLAI--LRTLRSLR-----KMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLN
.|. | . . . | . . |..|||| | | || | |...| . .
kekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrshee
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 192-338 | 7.1e-24 | 79.3 | In-house | 39-176 (255) | alignment | ||
Range on Protein: 192-338
Range on HMM: 39-176/255.0
LtqgplkdTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTESTTPDNHTQLKMLTVMDKkSGKSHKLYHYKIITWPDKS
| | .... | . . |||.. |.|. ||. ||| . | . ...||.|.|.. |.... . . | |.. ||. |..|
l.......tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlge.kkkthtvkhysykGWiekn
IALSNLAILRTLRSLRKMpGPIVVHCSAGIGRTGTFAAIEVGAQCLL
|| |. |. ..|||||.||||. .|. .|. | ..
aPelareilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmi
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 195-370 | 4.3e-25 | 82.8 | In-house | 98-281 (302) | alignment | ||
Range on Protein: 195-370
Range on HMM: 98-281/302.0
GPLKDTAMDIWRMVLQEGVAAICMLCELIENGRPKCEPYFPDTEGQVLTFGEITVTCTES-TTPDNHTQLKML---TVMDKKSGKSHK-LYHYKI---IT
| |.| | .. | || . ||...|.. || .|. | |..|.||. ||. . | .. | | . || | . | .| . .| .
vpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsa
WPDKSIALSNLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLV
|||. . | |. ..||||||.|||||. || | | .. | ...| ||.|| .|| ..| . |.
wpdhGapkeaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyll
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 264-373 | 1.6e-18 | 62.2 | In-house | 32-139 (145) | alignment | ||
Range on Protein: 264-373
Range on HMM: 32-139/145.0
KMLTVMDKKSGKSHKLYHYKIITWPDKSIALSNLAILRTLRSLRKM---PGPIVVHCSAGIGRTGTFAAIEVGAQcllNGkaFRPADLVRAVRHCRLNSV
|.... ... ... ..| . ||| .. . .|. |. ... .||..||||||.|||||..|. . . .| . . . .. || .| ..|
tvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmll...lg..vsleealelvrsqrpgav
QMDTQYLMLVEAI
. . |. .| |..
pnpgqlrflyefe
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 269-366 | 1.6e-08 | 29.9 | In-house | 70-165 (194) | alignment | ||
Range on Protein: 269-366
Range on HMM: 70-165/194.0
MDKKSGKSHKLYHYKII-----TWPDKSIALSNLAILRTLRSlRKMPGPIVVHCSAGIGRTGTFAAIevgaqCLLNGKAFRPADLVRAVRHCRLNSVqMD
|.. ........|.. | |. .| |. | .. . . .. .| ..||| ||.|||||..| |. . . . .. .| .| ... .
YdpeefekagieylklpfpddgtvPsleillrfldlvdefln.edpggvvaVHCkaGlgRtGtlvaa.....YLiyrlgmsaeeAialfrekRpgai.pn
TQY
.|
qdy
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 272-370 | 1.4e-16 | 56.0 | In-house | 40-138 (144) | alignment | ||
Range on Protein: 272-370
Range on HMM: 40-138/144.0
KSGKSHK--LYHYKIITWPDKSIALSNLAILRTLRSLRKM---PGPIVVHCSAGIGRTGTFAAIEvgaQCLLNGkaFRPADLVRAVRHCRLNSVQMDTQY
. . ..| . ||| .. . .|..|. ... .||..||||||.|||||..|. ....| . . . .. || .| ..|. . |.
yepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaay...lmkklg..lsleealalvrsrrpgavpnpgql
LMLV
.|
rfLl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 274-375 | 1e-08 | 28.9 | In-house | 88-192 (440) | alignment | ||
Range on Protein: 274-375
Range on HMM: 88-192/440.0
GKSHKLYHYKiiTWPDKSIALSNLAILRTLRSLRK-----MPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLM
.. | |||. ||||.. .|. .. . . ||..|||||| |||| |.. . .. ..| | . || || .
srtlkqyhyq..gwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyaf
LVEAILD
. ||.|.
vheavle
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 276-332 | 7.5e-06 | 19.5 | In-house | 217-287 (349) | alignment | ||
Range on Protein: 276-332
Range on HMM: 217-287/349.0
SHKLYHYKIITWPDKSIALSNLAILRTLRSLR--------------KMPGPIVVHCSAGIGRTGTFAAIEV
..|. .. |.| |. | .||..| . ...|||||| ||||.. ...
PyellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldl
|
|||||||||
PTPc_DSPc_SM00012 | 279-374 | 2.9e-24 | 80.7 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 279-374
Range on HMM: 2-104/105.0
LYHYKIITWPDKSIALSNLAILRTLRSLRKMPG------PIVVHCSAGIGRTGTFAAIEVGAQCLLNG-KAFRPADLVRAVRHCRLNSVQMDTQYLMLVE
..||.. .|||... . .||..||...| |.|||||||.||||||.|... | | .. | . ..|...|. | ..||...|||.| .
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
AIL
|.|
all
|
|||||||||
Y_phosphatase3 | Tyrosine phosphatase family | 296-330 | 8.3e-06 | 20.9 | Pfam-A | 110-144 (164) | alignment | ||
Range on Protein: 296-330
Range on HMM: 110-144/164.0
NLAILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAI
. |. . |. |.. .||...||.|| ||| .||.
kkayrkvlealaeeegpvlfHCtaGKDRTGvvaal
|
|||||||||
0048567 | (Phosphotyrosine protein) phosphatases II | 298-366 | 9.2e-06 | 20.1 | In-house | 62-128 (157) | alignment | ||
Range on Protein: 298-366
Range on HMM: 62-128/157.0
AILRTLRSLRKMPGPIVVHCSAGI---GRTGTFAAIevgaqCLLNGKAFRPADLVRAVRHCRLNSVQMDTQY
. . |..|.. ...|.|||.|| |||.|... |. | |.. .. .| .| .|| ..
klnkflkilelagkaiavhckaglkkrgrtatLigc.....Ylilhlgftpeeaiaplrivrpgsvpfrdas
|
|||||||||
subfamily_CDC14_pd | Subfamily CDC14 | 299-365 | 8.6e-07 | 23.1 | In-house | 252-313 (328) | alignment | ||
Range on Protein: 299-365
Range on HMM: 252-313/328.0
ILRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIevgaqCLLNGKAFRPADLVRAVRHCRLNSVQMDTQ
. . |. . |. | |.||| ||.|||||. | |.. | |. . .| || || |
vkkfleiaekaeGaiavhCkaGLGrtGtLiac.....ylmkhyrftaaeaiawlricrPGsvigpqq
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 300-374 | 5.4e-09 | 30.3 | In-house | 218-292 (297) | alignment | ||
Range on Protein: 300-374
Range on HMM: 218-292/297.0
LRTLRSLRKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAIL
| .||. . ...||||||.||.| .| .. | ... | ... .|. | || |. .| .|.|
leslraemprnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavl
|
|||||||||
PTEN_1 | 304-356 | 1.1e-06 | 23.6 | In-house | 121-171 (196) | alignment | |||
Range on Protein: 304-356
Range on HMM: 121-171/196.0
RSLRK---MPGPIVVHCSAGIGRTGTFAAievgaQCLLNGKAFRPADLVRAVRHCR
. .. . ..||| ||.||.|| .| .|. . . . . .. || .|
iewllsdpngnvVlVHCkaGlgRsGtvva.....ayLmykgkltadeAlelvrekR
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 307-369 | 1.5e-09 | 32.0 | In-house | 244-307 (319) | alignment | ||
Range on Protein: 307-369
Range on HMM: 244-307/319.0
RKMPGPIVVHCSAGIGRTGTFAAIEVGAQCLLNG-KAFRPADLVRAVRHCRLNSVQMDTQYLML
|. ||.||||| |.||||. | .. . | . .. .|| ||. | ..|. || ..
resqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefi
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 310-332 | 7.7e-07 | 23.1 | In-house | 262-284 (350) | alignment | ||
Range on Protein: 310-332
Range on HMM: 262-284/350.0
PGPIVVHCSAGIGRTGTFAAIEV
||.||||||.|||||. ...
sspilvhCsaGvGrtGtlvtlDs
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 310-371 | 1.5e-06 | 22.8 | In-house | 114-170 (182) | alignment | ||
Range on Protein: 310-371
Range on HMM: 114-170/182.0
PGPIVVHCSAGIGRTGTFAAievgaQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVE
| . ||| || |||| | |. | . ... .. ||. | .|.| .| ...|
egkvavhChaGlGrtGvlia.....cylvyakrltaekaiklvrskrpksiqtreqvelvke
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 313-374 | 5.8e-08 | 27.0 | In-house | 1-62 (69) | alignment | ||
Range on Protein: 313-374
Range on HMM: 1-62/69.0
IVVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAIL
.|||||.| |||||| || | . | . |. .| || | . .|... .|.
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalv
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 314-373 | 1.1e-07 | 26.1 | In-house | 1-60 (69) | alignment | ||
Range on Protein: 314-373
Range on HMM: 1-60/69.0
VVHCSAGIGRTGTFAAIEVGAQCLLNGKAFRPADLVRAVRHCRLNSVQMDTQYLMLVEAI
|||||.| |||||| || | . | . |. .| || | . .|... .|.
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdal
|