Gene F47B3.2 in Caenorhabditis elegans

Synonym: CELE_F47B3.2, F47B3.2

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily CelePTP-sf6
Protein sequence
ID Type Fasta BLAST phosphatome Note
CeleP090_AA protein Get Run
CeleP090_AA_2-83 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 1-112 2e-74 245.4 In-house 196-307 (307) alignment 
Range on Protein: 1-112
Range on HMM: 196-307/307.0
MGAINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKETYEGLLLTKNYE
..||||.|||.|||||||||||||||||||||.|||..||||.|||||||||||||.|.||||||||||||.|.|||||||||||.|||||.||||||||
ltainlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyflelyketyeellltknye

EKYAKWLDDYNT
||||||||||||
ekyakwlddynt
subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 3-98 3.6e-31 102.9 In-house 210-305 (305) alignment 
Range on Protein: 3-98
Range on HMM: 210-305/305.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKETYEGLLLTKN
...|. |.     |.|||||||.||.|||| |  |..|. .  .|  | .||  .|.|| ..||.. ||..||||.|.|||| .|| |  || ..|
slellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyflekykekyaalltaen
0036941 (Phosphotyrosine protein) phosphatases II 3-84 1.5e-24 82.3 In-house 190-279 (297) alignment 
Range on Protein: 3-84
Range on HMM: 190-279/297.0
AINLIEAVNY------DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQ--GINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
 ...||.|.       . .||.||||||||||||.... |... . .    .. |....| ..|.||. |.||. ||......|||... 
lldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkk
subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 3-84 5.1e-24 79.6 In-house 208-289 (305) alignment 
Range on Protein: 3-84
Range on HMM: 208-289/305.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
 ..|.|       |.|||||||.||.|..| .  |.|....|   .| .|..  ||.||  .|||.|||...|.|.|.||..
ilellekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfrk
0045450 (Phosphotyrosine protein) phosphatases II 3-83 1.2e-23 79.7 In-house 217-305 (307) alignment 
Range on Protein: 3-83
Range on HMM: 217-305/307.0
AINLIEAVNY------DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINC--KDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFL
....||.|.       . .||.|||||||||.||.... |... . ..  .   |. . |...|.||. |.|.. ||......|||..|
lldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelll
0040439 (Phosphotyrosine protein) phosphatases II 3-83 7.1e-23 76.9 In-house 162-247 (249) alignment 
Range on Protein: 3-83
Range on HMM: 162-247/249.0
AINLIEAVNY------DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFL
....||||.       . .||.|||||||||.||.... |... .    .. |..  |...|.||..|.|.. ||......|||..|
lldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqleke.lgvdleeavkllrsqRpgavqnpeqyrflyeallelll
Y_phosphatase Protein-tyrosine phosphatase 3-80 7.5e-23 76.5 Pfam-A 155-235 (235) alignment 
Range on Protein: 3-80
Range on HMM: 155-235/235.0
AINLIEAVNYDT----NPVVVHCSAGVGRSGTIVGISLIMDKMIQGINcKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
 ..||..|. ..    .||||||||||||.||.| ........ .. .  |....|.|.|.||. ..|...||.......||
lldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeee.vdvlqivkelRkqRpgmvqsleqYiflykaile
Y_phosphatase Protein-tyrosine phosphatase 3-80 7.5e-23 76.5 In-house 155-235 (235) alignment 
Range on Protein: 3-80
Range on HMM: 155-235/235.0
AINLIEAVNYDT----NPVVVHCSAGVGRSGTIVGISLIMDKMIQGINcKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
 ..||..|. ..    .||||||||||||.||.| ........ .. .  |....|.|.|.||. ..|...||.......||
lldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeee.vdvlqivkelRkqRpgmvqsleqYiflykaile
0043147 (Phosphotyrosine protein) phosphatases II 3-75 9.1e-21 69.8 In-house 87-154 (172) alignment 
Range on Protein: 3-75
Range on HMM: 87-154/172.0
AINLIEA--VNYDTNPVVVHCSAGVGRSGTIVGISLIMdkmiQGInckDMKKLVEEIRNQRHYAIQTEAQYMYIH
....|.   .... .||.|||||||||.||.| . |..    .|.   .. . |...|..| .|.|.. ||....
flefidellalspggpvlVHCsaGvgRtgtlvaaylml....lgl...sleeavalvrekRpgavqnpsqyrfly
0041856 (Phosphotyrosine protein) phosphatases II 3-84 9.3e-21 69.7 In-house 98-173 (182) alignment 
Range on Protein: 3-84
Range on HMM: 98-173/182.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKmiqginCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
....||.|. . .||.|||||||||.||.|.. |.. .        .. . |...|..|. ...|. || .....|||..| 
lldfieevleeggpvlVHCsaGvgRtgtlvaaylmkkl......gvsleeavklvrsrRpgmvitpnqyfflqlallellll
0036282 (Phosphotyrosine protein) phosphatases II 3-76 4.4e-20 67.5 In-house 91-164 (174) alignment 
Range on Protein: 3-76
Range on HMM: 91-164/174.0
AINLIEAVNYD--TNPVVVHCSAGVGRSGTIVGISLIMDKMIqgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHR
.....| .  .   .||.|||||||||.||.|.. |..  ..   .  |  .|| |.|.||....||. ||.... 
fvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll..eslvdaldlvrelRlqrpgmvqtpsQyrflyy
subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 3-83 2.3e-19 64.5 In-house 193-272 (288) alignment 
Range on Protein: 3-83
Range on HMM: 193-272/288.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVgISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFL
 ..|.| ..  ..|.|||.||||||.||.. ..||. ....  .   ...|... |..|  ||||| ||.|.||..||..|
plrllevlkslqkPivvhssaGvGrtgtli.lilialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleell
0048076 (Phosphotyrosine protein) phosphatases II 3-81 5.8e-18 60.4 In-house 70-142 (145) alignment 
Range on Protein: 3-81
Range on HMM: 70-142/145.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDkmiqgiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY
....||..  . .||.|||||||||.||.|.. |..       .  .. . .|..|.||..|.... |. ......||.
flefieealkeggpvlVHCsaGvgRtgtlvaaylmll......lgvsleealelvrsqrpgavpnpgqlrflyefelel
0044763 (Phosphotyrosine protein) phosphatases II 3-82 1.4e-17 59.4 In-house 98-171 (178) alignment 
Range on Protein: 3-82
Range on HMM: 98-171/178.0
AINLIEAVN-YDTNPVVVHCSAGVGRSGTIVGISLIMDKmiqginCKDMKKLVEEIRNQRHyAIQTEAQYMYIHRVLLEYF
....||..   . .||.||||||||||||.| . |..          .. . .|..|..|  ..... |. ..... |...
fvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl......glsleeaielvrerRp.ivpnpgqlrqLyefelrll
0048179 (Phosphotyrosine protein) phosphatases II 3-76 3.7e-17 57.9 In-house 72-139 (144) alignment 
Range on Protein: 3-76
Range on HMM: 72-139/144.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMdkmiqgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHR
....||..  . .||.|||||||||.||.| . |..       .  .... ....|..| .|.... |......
flefieealeeggpvlVHCsaGvgRtgtlvaaylmk......klglsleealalvrsrrpgavpnpgqlrfLle
subfamily_Cele-PTP-1_pd Subfamily Cele-PTP-1 3-105 2.3e-15 51.5 In-house 180-285 (290) alignment 
Range on Protein: 3-105
Range on HMM: 180-285/290.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKETYEGLLLTK---NY
...||. |.  . ||.|||  |. || ..  | | . |...  .   ........|.||  ||... .. ..  ... .. |  ....|    .|   ..
llsliqkvkasktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivllaievldqfaeeetekkakaee

EEKYAK
.| | |
ketykk
subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 3-105 1.2e-14 48.7 In-house 198-298 (312) alignment 
Range on Protein: 3-105
Range on HMM: 198-298/312.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKmIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKETYEGLLLTKnYEEK
|  |. ||. | .||. ||||||||.||.. |  ..   ..    ...|.    .|..|  .... .||.|  |..||..        .    || ..| 
alrllsavkkdkkpviahcsagvgrtgtlaliesmiaa.lrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskglykrneqewtk.fket

YAK
|||
yak
subfamily_PTPMT1_pd Subfamily PTPMT1 3-66 3e-09 31.5 In-house 96-156 (171) alignment 
Range on Protein: 3-66
Range on HMM: 96-156/171.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKmiqGINCKDMKKLVEEIRNQRHYAIQ
....|| |  . . | ||| || |||.|.|.  |.. .    .. ..  | ....|.. . | .
gvefiekvaskgkrvYvHCkaGrgRsatlvacylmkke...klspeeAlkalkkkRkiirlakk
DSPc Dual specificity phosphatase, catalytic domain 3-60 8.2e-09 30.4 Pfam-A 62-116 (133) alignment 
Range on Protein: 3-60
Range on HMM: 62-116/133.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLiMDKmiQGINCKDMKKLVEEIRNQ
|.. ||..  . . |.||| ||. ||.|..   | |..  .... ..  ..|.| |..
avefiekaeqkgkkvlVHCqaGisRSatliiaYl.mkt..knlslneAyefvkerrsk
DSPc Dual specificity phosphatase, catalytic domain 3-60 8.2e-09 30.4 In-house 62-116 (133) alignment 
Range on Protein: 3-60
Range on HMM: 62-116/133.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLiMDKmiQGINCKDMKKLVEEIRNQ
|.. ||..  . . |.||| ||. ||.|..   | |..  .... ..  ..|.| |..
avefiekaeqkgkkvlVHCqaGisRSatliiaYl.mkt..knlslneAyefvkerrsk
subfamily_DSP10_pd Subfamily DSP10 3-59 2.3e-08 28.1 In-house 81-134 (159) alignment 
Range on Protein: 3-59
Range on HMM: 81-134/159.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVgISLIMDKMiqGINCKDMKKLVEEIRN
|.. || ..   . |.||| ||. || |.| |. .| ..  ... .|  |.|.| | 
alefieearkkgsrvLvhCqaGisrsatvv.iaYlmkhl..nlslndaykfvkekrp
subfamily_DSP6_pd Subfamily DSP6 3-46 4.9e-07 23.4 In-house 82-124 (158) alignment 
Range on Protein: 3-46
Range on HMM: 82-124/158.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVgISLIMDKMIQGIN
||..|.    . . |.||| ||. || |.. .. .| |.   .|
aiefidearskkskvlvhClaGisrsvtvt.laylmkklalsln
subfamily_DSP8_pd Subfamily DSP8 3-87 5.6e-07 23.3 In-house 82-156 (159) alignment 
Range on Protein: 3-87
Range on HMM: 82-156/159.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVgISLIMDKMiqGINCKDMKKLVEEIRnqrhYAIQTEAQYMyihRVLLEYFLELHK
... |. ..     |.||. ||  || |.. |. || ..   ..  .  . | | |     .|. . ...     ||||  ||..
svefidkaksengrvlvhvlaGisrsatva.iayimktl..emsldeayrfvkekr....ptispnlnfl...gqLleyekelkl
subfamily_DSP15_pd Subfamily DSP15 3-60 9.7e-07 23.0 In-house 67-121 (151) alignment 
Range on Protein: 3-60
Range on HMM: 67-121/151.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMdkmIQGINCKDMKKLVEEIRNQ
....| .     . |.||| ||| || |.| . |.    .  .| .|. . ... |  
svefihkcRlkeenvlvhClaGvsRsvtlvvaYlmt...vtelnwrdalevikaaRsv
subfamily_DSP1_pd Subfamily DSP1 3-55 1.1e-06 22.9 In-house 84-133 (163) alignment 
Range on Protein: 3-55
Range on HMM: 84-133/163.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIqgiNCKDMKKLVE
.|. |..|.     | .|| ||. || |.. . |.. | .   . ..  ..| 
viefidevkkknGkvlihCqaGisRsstlclaylmktkrv...sleeafdfvk
subfamily_MTMR3_pd Subfamily MTMR3 3-44 2.3e-06 19.6 In-house 258-300 (442) alignment 
Range on Protein: 3-44
Range on HMM: 258-300/442.0
AINLIEAVNYDTNPVVVHCSAGVGRSGTIVGIS-LIMDKMIQG
|....|||. .. ||.|||| |  |   || .. |..|.  . 
avkvveavdkegrpvlvhCsdGWdrttqivalakllldpyyrt
0040438 (Phosphotyrosine protein) phosphatases II 4-111 1.2e-25 85.9 In-house 195-305 (317) alignment 
Range on Protein: 4-111
Range on HMM: 195-305/317.0
INLIEAVNYD----TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGInCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKETYEGLLLTKNY
....|||.       .||.|||||||||.||.... |... . ..  . |... |.|.|.||..|.||..||......||||..  .. ..   | .| .
ldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeg.gvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkll

EEKYAKWLDDYN
.... ..|||. 
klliplalddvk
0050432 (Phosphotyrosine protein) phosphatases II 4-84 3.3e-25 84.5 In-house 220-301 (308) alignment 
Range on Protein: 4-84
Range on HMM: 220-301/308.0
INLIEAVNYD--TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
....|.|.     .|.||||||||||.||.. . |... . .. .. |. ..|  .| ||....||. ||....|.||||.. 
ldflelvrkslpggpivVHCsaGvGRtGtfialdllleqleke.ggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
DSPc_SM00195 4-82 7.9e-25 83.0 In-house 181-262 (263) alignment 
Range on Protein: 4-82
Range on HMM: 181-262/263.0
INLIEAVNYD----TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINcKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
..|..||. .    ..|.||||||||||.||.| |..|..|. .. .  |....|.|.|.||. ..||..||..|....|||.
lellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekk.vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
PTPc_SM00194 4-82 7.9e-25 83.0 In-house 181-262 (263) alignment 
Range on Protein: 4-82
Range on HMM: 181-262/263.0
INLIEAVNYD----TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINcKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
..|..||. .    ..|.||||||||||.||.| |..|..|. .. .  |....|.|.|.||. ..||..||..|....|||.
lellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekk.vdifeivkelRkqRpgmvqtleqYlfiyeaileyi
0047943 (Phosphotyrosine protein) phosphatases II 4-82 1.4e-24 82.5 In-house 189-272 (273) alignment 
Range on Protein: 4-82
Range on HMM: 189-272/273.0
INLIEAVNY------DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
...||.|.       . .||||||||||||.||.. . |..| .. . .. |....|  .|.||....||. ||......||||.
lefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqleke.ggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
0051299 (Phosphotyrosine protein) phosphatases II 4-82 2.3e-24 81.8 In-house 205-286 (288) alignment 
Range on Protein: 4-82
Range on HMM: 205-286/288.0
INLIEAVNYD----TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
......|.       .||||||||||||.||.. . |... . .. .. |. ..|. .|.||....||. ||......||||.
ldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqleke.ggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
0046845 (Phosphotyrosine protein) phosphatases II 4-84 2.7e-24 81.5 In-house 188-276 (284) alignment 
Range on Protein: 4-84
Range on HMM: 188-276/284.0
INLIEAVNYD------TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGIN--CKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
......|.         .|.||||||||||.||.. . |... ....    . |. ..|  .|.||....||..||......||||.. 
leflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylkl
0039614 (Phosphotyrosine protein) phosphatases II 4-85 3.5e-24 81.2 In-house 206-292 (297) alignment 
Range on Protein: 4-85
Range on HMM: 206-292/297.0
INLIEAVNY------DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLEL
....|.|.       . .||.|||||||||.||.... |... .  .  . |... |.|.|.||..|.||. ||......|||...  
leflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqleke.ggvdvleavkelreqRpgavqtpsqyrflydallellkrk
0045098 (Phosphotyrosine protein) phosphatases II 4-84 4e-23 77.6 In-house 182-274 (278) alignment 
Range on Protein: 4-84
Range on HMM: 182-274/278.0
INLIEAVNY--------------DTNPVVVHCSAGVGRSGTIVGISLIMDKMiqGiNCKDMKKLVEEIRNQRHY-AIQTEAQYMYIHRVLLEYFLE
.. |....               . .||.|||||||||.||.|.. |... .  . .  |. . |.|.|.||.. |.|.. ||......|||..| 
lefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..e.ggvdlleavkelrsqRpglavqnleqyrflyefllelllr
subfamily_PTPRA_pd Subfamily PTPRA 4-85 1.7e-21 71.5 In-house 214-298 (330) alignment 
Range on Protein: 4-85
Range on HMM: 214-298/330.0
INLIEAVN----YDTNPVVVHCSAGVGRSGTIVGISLIMDKMiQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLEL
..|...|.      ..|.||||||||||.|| . .. ..... .  .  |. . |...|.||   .||. || .|..|||||.|  
lkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlerv.kaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylyg
0046846 (Phosphotyrosine protein) phosphatases II 4-82 3.1e-19 64.8 In-house 99-173 (176) alignment 
Range on Protein: 4-82
Range on HMM: 99-173/176.0
INLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKmiqgiNCKDMKKLVEEIRNQRH-YAIQTEAQYMYIHRVLLEYF
...|. .  . .||.||||||.||.||.| . |.. .     .. .. . ....|.||. .|.||..|| ......|...
lefirealkeggpvlVHCsaGigRtgtlvaayllele.....kglsveealalvreqRplgavqtpeQyrflyefellll
subfamily_Ptp69D_pd Subfamily Ptp69D 4-82 6e-18 60.0 In-house 205-286 (307) alignment 
Range on Protein: 4-82
Range on HMM: 205-286/307.0
INLIEAV----NYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
..||| |    . .  |.||||||||||||..| ........ .  .. |. . | ..|.||   .|  .||....| ||.| 
lklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlka.edkvdifetvkdLrsqRnllvqsleqYvflyralldys
0049772 (Phosphotyrosine protein) phosphatases II 4-87 1.5e-16 56.5 In-house 203-285 (314) alignment 
Range on Protein: 4-87
Range on HMM: 203-285/314.0
INLIEAVnYDTNPVVVHCSAGVGRSGTIVGISLIMDKMiqgiNCkDMKKLVEEIRNQRH-----YAIQTEAQYMYIHRVLLEYFLELHK
...||..  . .||.|||.||.||.|| | . ..| ..    .. .... .|..|..|.      .|..  || .|...||||.  |.|
lefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkll....gv.sleealedvrlkRpinpnpgfieqleqyefilealleylkflkk
subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 4-74 1.2e-11 39.0 In-house 204-273 (301) alignment 
Range on Protein: 4-74
Range on HMM: 204-273/301.0
INLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYI
 .|.| |    .|.|||||||.||| . .|   .  ..    .  .... ....|..|  ..||. |  ..
fdlmelvkksekPivvhcsaGiGrsvafigteylarevead.ptieltealkhlrehrwngvqtnsqlywm
PTPc_motif_SM00404 4-72 1.2e-08 30.0 In-house 70-131 (140) alignment 
Range on Protein: 4-72
Range on HMM: 70-131/140.0
INLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLImDKmiQGINCKDMKKLVeeiRNQRhYAIQTEAQYM
.. ||... .   |.||| ||| ||.|..   |. ..  .... ..  ..|   ...|  .|.  ....
ldfienaekkggkvlVHCqaGvSRSatliiaYlm.ry..rqlslaeayefv...kerR.piispnlnfv
subfamily_DSP19_pd Subfamily DSP19 4-61 8.5e-08 26.7 In-house 79-130 (152) alignment 
Range on Protein: 4-61
Range on HMM: 79-130/152.0
INLIEAVNYDTNPVVVHCSAGVGRSGTIVgISLIMDKMiqGINCkdmKKLVEEIRNQR
.. || .    . |.|||.||| || ..| |. .| |    ...   .. .|..|..|
ldFieearskdgavlvHCnAGvSRsasvv.iaylmkke..elsl...eealelvrear
PTPc_DSPc_SM00012 5-80 3.8e-25 83.5 In-house 27-105 (105) alignment 
Range on Protein: 5-80
Range on HMM: 27-105/105.0
NLIEAVNYD---TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
. .. ....   ..||||||||||||.||.| ........ .. .. |....|.|.|.||. ..|||.||....|.|||
ravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyralle
0043336 (Phosphotyrosine protein) phosphatases II 5-82 1.2e-22 76.2 In-house 197-277 (278) alignment 
Range on Protein: 5-82
Range on HMM: 197-277/278.0
NLIEAVNY----DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGInCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
....||.     . .||.|||||||||.||.... |... .  .  . |. . |.|.|.||. |.||. ||......||||.
dflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeg.gvdleeavkelreqRpgavqtpsqyrflyealleyl
0037934 (Phosphotyrosine protein) phosphatases II 5-82 4.9e-22 74.1 In-house 164-242 (243) alignment 
Range on Protein: 5-82
Range on HMM: 164-242/243.0
NLIEA-----VNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMiqginCKDMKKLVEEIRNQRHY-AIQTEAQYMYIHRVLLEYF
. ||.     .. . .||.|||||||||.||.. . |.....     . |. . |...|.||.. |.||. ||......|||..
efieellsllaldsggpvlVHCsaGvgRtGtliaaylmllll.....gvdleeavkllreqRpgkavqtpsqyrflyeallell
0042113 (Phosphotyrosine protein) phosphatases II 5-82 5.5e-22 73.8 In-house 162-243 (245) alignment 
Range on Protein: 5-82
Range on HMM: 162-243/245.0
NLIEAVNY-----DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
...|.|.      . .||.|||||||||.||.... |... .     . .. . |.|.|.||. |.||. ||......|||..
dflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqleke.lgvsleeavkelrsqRpgavqtpsqyrflyeallell
subfamily_DSP23_pd Subfamily DSP23 5-74 3.4e-07 25.0 In-house 75-138 (148) alignment 
Range on Protein: 5-74
Range on HMM: 75-138/148.0
NLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDkmiQGINCKDMkklVEEIRNQRHYAIQTEAQYMYI
...|  .  .. | |||  | ||.||..   |.     ...   .    . |.|..|  ...|  |   .
rvveeaeekneavsvhcllgrgrtgtmlacylvke...rklaaaea...iaevrrlrpgsvetveqeklv
subfamily_DSP14_pd Subfamily DSP14 5-59 5.1e-06 20.5 In-house 74-125 (157) alignment 
Range on Protein: 5-59
Range on HMM: 74-125/157.0
NLIEAVNYDTNPVVVHCSAGVGRSGTIVGISLiMDkmIQGINCKDMKKLVEEIRN
. ||.|. .   ..||| ||| || ... . | |    . .. ..  |||...|.
dkieevkkkggktlvhCvaGvSRSAslclayl.mk..yeklsLreayklvksaRp
0051429 (Phosphotyrosine protein) phosphatases II 6-94 7.1e-21 70.5 In-house 143-237 (272) alignment 
Range on Protein: 6-94
Range on HMM: 143-237/272.0
LIEAVNYdTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKD-------MKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKETYEGLL
|.|...   .||.||||||..|.||.| . |..  .     ..|       . . |||.| ||..|.|||.||......|||.. .|    .| ||
llellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsllsvraeyll
0051082 (Phosphotyrosine protein) phosphatases II 6-79 5.4e-17 57.3 In-house 83-150 (151) alignment 
Range on Protein: 6-79
Range on HMM: 83-150/151.0
LIEAVN-YDTNPVVVHCSAGVGRSGTIVGISLIMDKmiqgincKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLL
..|...  . .||.||||||.||.||.|.. |.. .        .. . .||.| .|....|.. |.......||
flellldkkngpvlvHCsaGkgRTGtlvalylmllg.......vsleealeeyrlkrpgvvqpnqqflfqlfall
subfamily_DSP12_pd Subfamily DSP12 6-60 5.7e-07 24.1 In-house 74-125 (155) alignment 
Range on Protein: 6-60
Range on HMM: 74-125/155.0
LIEAVNYDTNPVVVHCSAGVGRSGTIVgISLIMDKmiQGINCKDMKKLVEEIRNQ
 ||    . . |.||| ||| || ||| |  .| |  .......  |||.|....
FieealeeegavlvHCqagvSRSvtiv.iAYlmkk..eklslekAlklvkekkpe
subfamily_PTPN13_pd Subfamily PTPN13 7-81 3.9e-20 67.2 In-house 195-268 (273) alignment 
Range on Protein: 7-81
Range on HMM: 195-268/273.0
IEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCkDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY
.  .. |. |.|||||||.|||||.. |  ... . .  .  |.|..|...|.||.  .||. ||.......|| 
vrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdkef.dvkeivrklreqrqgvvqtkdqyifvykailev
subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 7-83 2.3e-16 54.6 In-house 196-271 (285) alignment 
Range on Protein: 7-83
Range on HMM: 196-271/285.0
IEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCkDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFL
.. ||   .|..|||||||||. |.|||     ....  |  .|  .| |.|  |  |.|.  |..... ||.|||.
vkkvnpkekpicvhcsagvgrtatfvgidyatirimenpni.emldivremramrfqavqshmqflflyvvlmeyfi
subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 7-81 4.8e-15 50.0 In-house 209-282 (290) alignment 
Range on Protein: 7-81
Range on HMM: 209-282/290.0
IEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCkDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY
. ..   . |||||||||.||.||.| |   .. ...| .  |. .||  .|| |  ..| . ||. . ..||..
lrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkel.dlldlvralrnsrlnsvqvdiqylalveilldl
subfamily_egg_pd Subfamily egg 7-111 6e-15 49.7 In-house 194-292 (307) alignment 
Range on Protein: 7-111
Range on HMM: 194-292/307.0
IEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCK-DMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKEtyeglllTKNYEEKYAK
.  .   ..||||..  || ...|.| | . . ....|   |  ... |  .| .|......  .|....|..| .| ..          .|. .  | .
lrklrnlskpvvvqdilGvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffrdvigs.......akeldvdyer

WLDDYN
||... 
wleers
subfamily_hpo-7_pd Subfamily hpo-7 7-85 3.9e-11 37.3 In-house 147-230 (263) alignment 
Range on Protein: 7-85
Range on HMM: 147-230/263.0
IEAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCK-----DMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLEL
|  |. .  ..|||||.|.|||   . . |.  |||. ..       |  .|.||.|..|. ||.|  |  .   ..|...|. 
ilkvarnskslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnn
PTEN_1 7-87 6.9e-10 34.0 In-house 121-193 (196) alignment 
Range on Protein: 7-87
Range on HMM: 121-193/196.0
IEAVNY--DTNPVVVHCSAGVGRSGTIVGISLIMDKMiqgincKDMKKLVEEIRNQR-HYAIQteaqyMYIHRVLLEYFLELHK
||..    . | |.||| ||.|||||.|   |.  .        .... .| .| .| . |..     .  .. ||||| ||..
iewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgk......ltadeAlelvrekRppgapn.....spsqerlleyfaella
0049260 (Phosphotyrosine protein) phosphatases II 8-75 7.6e-19 63.3 In-house 82-143 (152) alignment 
Range on Protein: 8-75
Range on HMM: 82-143/152.0
EA-VNYDTNPVVVHCSAGVGRSGTIVGISLIMdkmiqgiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIH
|    .. .||.|||||||||.||.| . |..       .  .... |. .|..| .|.... |.....
eklaldkggpvlVHCsaGvgRtgtlvaaylml.......lgvsleeavalvrekRpgavpnpgqlrfly
subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 8-84 2.9e-15 51.2 In-house 215-290 (325) alignment 
Range on Protein: 8-84
Range on HMM: 215-290/325.0
EAVNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCkDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
 |    . |..|||||||||.|. . .  ...|.|.  .  |. . |. .|..|   ..|  ||. |.  | |... 
tantkastpilvhcsaGvGrtGvfislysalakvieesrv.difgfvkklrkdrpsmvetvdqyiliyealveayms
subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 9-82 8.5e-20 66.1 In-house 210-283 (305) alignment 
Range on Protein: 9-82
Range on HMM: 210-283/305.0
AVNYDTN-PVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
. . | . |..|||||||||.|. . ... .... .  .  |. ... ..|..| ...|| .||...| .| |. 
dqkkdkgvpllVhCsagvgRtGvfiavdialerlkkE.evvdvfevlkqlRskrmkmvqtldqYvflhdaldeli
subfamily_PTPN12_pd Subfamily PTPN12 10-84 2.2e-20 67.7 In-house 203-279 (290) alignment 
Range on Protein: 10-84
Range on HMM: 203-279/290.0
VNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGIN--CKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
 . . .|.|||||||||| |||. | .. . . ...   . |. .|| |.|.||. ..||. || .... ..|.. .
qesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqk
subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 10-85 1.2e-14 48.6 In-house 196-272 (281) alignment 
Range on Protein: 10-85
Range on HMM: 196-272/281.0
VNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRN-QRHYAIQTEAQYMYIHRVLLEYFLEL
.   . | |.|||||||||||.. . . .. .   .   |.|..|  .|   |  ..||  ||| | .|||.. .  
irarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldfgvay
subfamily_PTPN1_pd Subfamily PTPN1 10-89 5.8e-14 46.5 In-house 197-278 (290) alignment 
Range on Protein: 10-89
Range on HMM: 197-278/290.0
VNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQG--INCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKET
.. |  |.|.|||||.|||||.. .  .. .. .   ... |.|| . |.|..|.  |||  |  . .  .||    .....
lssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgds
subfamily_Cele-PTP-9_pd Subfamily Cele-PTP-9 10-85 5e-12 40.4 In-house 144-222 (255) alignment 
Range on Protein: 10-85
Range on HMM: 144-222/255.0
VNYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCK-----DMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFleL
|  |. .||||||.|.||| . | . |.  |||. ..       | ..|.||.|..|. ||.|  |  .   ..|...   
vvrdsksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlv..f
subfamily_PTPRD_pd Subfamily PTPRD 11-87 4.7e-24 79.9 In-house 211-286 (564) alignment 
Range on Protein: 11-87
Range on HMM: 211-286/564.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHK
. |. |.||||||||||.|| . |. ..... .  .  |. . |...|.|| . .||| ||..||...||.    ..
epdagPivVhCSaGVGRTGtfividamlerike.ektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnt
subfamily_PTPRB_pd Subfamily PTPRB 11-84 1.8e-21 71.4 In-house 215-287 (293) alignment 
Range on Protein: 11-84
Range on HMM: 215-287/293.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
. ...|.||||||||||.|| . .  ..... .  .. |.  .| |.|..| . .|||.||..||...|... .
taskrPivvhCsaGvGRtGtfialdrllqaiee.edyvdifgivaelReeRnllvqtekqYifihqcvldllrk
subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 11-80 5.4e-20 66.6 In-house 209-277 (288) alignment 
Range on Protein: 11-80
Range on HMM: 209-277/288.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
. ||.|..|||||||||.|| . .  ..|.. .  .  |.   |...|.||   .||. ||..|..|||.
qadtgpiivhCsaGvGrtgtFialdalidavee.edyiDvagtvaklRkqRallvqtlkqYefiyevlls
subfamily_PTPRG_pd Subfamily PTPRG 11-85 3.8e-18 60.0 In-house 217-290 (563) alignment 
Range on Protein: 11-85
Range on HMM: 217-290/563.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMdKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLEL
. .. |.||||||||||.|| . .. .. | ||  |  .. ...  || || . .||| ||...| .|||  .  
kaeaGPivvHcsaGvgrtGtyivldtll.kqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiask
subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 11-81 5.7e-17 56.6 In-house 189-258 (267) alignment 
Range on Protein: 11-81
Range on HMM: 189-258/267.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY
.   .|.||.||.||||||| . |   .... .  .  |. ... .||.||   ..|  .|.|||..| ||
engnrPlvvacsdGvGrsGtflvidsqlerakte.gvsdifdflrkirsqriglvdtkeryiyihellaey
subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 11-82 9.2e-17 56.0 In-house 198-268 (274) alignment 
Range on Protein: 11-82
Range on HMM: 198-268/274.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGInCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
|  . |||||||||.|| |  ..||. . .. . |   |. |.| ..| .|   .||. || .|||.| .| 
naklapvvvhCsaGiGrtGcfiaisiavrqlreei.vvdvlkivcnlrldrGGmvqtseqyelihralclyl
subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 11-83 1.6e-16 55.1 In-house 207-278 (315) alignment 
Range on Protein: 11-83
Range on HMM: 207-278/315.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFL
. .. ...|||||||||.| .. |  ..... .  .  |. ..|...|..| | .||| .| .|. ..||..|
gkkefsllvhcsaGvGrtGvvisidevvaqikr.trsvdvfnfvknlrakrpylvqteeeyafiydavledll
subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 11-81 1.9e-15 51.3 In-house 209-278 (439) alignment 
Range on Protein: 11-81
Range on HMM: 209-278/439.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMDKMiQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY
. .. ||||||||||||.|||. . . .... .  |  |.| .|. .|.||.  .|. .||..|.  .|| 
keeygpvvvhcsagvGrtGtiialdialeql.klenkvdikgivkvlrkqrkqmvqalcqyvfiynavled
subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 11-80 2.1e-13 45.1 In-house 167-237 (237) alignment 
Range on Protein: 11-80
Range on HMM: 167-237/237.0
NY--DTNPVVVHCSAGVGRSGTIVGISLIMdKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
..  .. | ..||||||||.| .. |  .. .  .  .  |. . |  | ..| | |||. ||..||...||
phvsesgpwiihcsagvgrtgiflvidaml.rqakekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 11-82 1.1e-11 39.0 In-house 259-344 (350) alignment 
Range on Protein: 11-82
Range on HMM: 259-344/350.0
NYDTNPVVVHCSAGVGRSGTIVGISLIMD-----KMIQGIN--------CKD-MKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
|  ..|..||||||||| ||.| .  ..      ....            .| .. .| |.|.||   .|.  |...|.  || ||
narsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivnelrkqrismvqnldqfifiYeallfyf
subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 12-88 5.4e-20 66.7 In-house 211-286 (318) alignment 
Range on Protein: 12-88
Range on HMM: 211-286/318.0
YDTNPVVVHCSAGVGRSGTIVGISLIMDKmIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKE
 ...|.|||||||||| |. . .. .... |.  .  |. . |...|.||   .||| || .|. ||||.    ..|
sgagpivvhCsaGvGrtGvfiavdiller.ikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdte
subfamily_PTPN6_pd Subfamily PTPN6 12-83 2.8e-19 64.3 In-house 225-298 (306) alignment 
Range on Protein: 12-83
Range on HMM: 225-298/306.0
YDTNPVVVHCSAGVGRSGTIVGISLIMDKM-IQGINCK-DMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFL
 .. |.|||||||.|| ||.. | ......  .|.... |..|||. .|.||   .|||.|| ...... .|  
aeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyie
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 12-82 8.3e-19 62.9 In-house 219-290 (298) alignment 
Range on Protein: 12-82
Range on HMM: 219-290/298.0
YDT--NPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
...  .||.|.|||||||||| . |. ..... .  .  |. . |. .|..|  |.|||.||..|. . ||..
qqagnkpvivqCsaGvgRsGtfiaidsvlervkk.eqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleal
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 12-83 4.3e-18 60.3 In-house 195-265 (270) alignment 
Range on Protein: 12-83
Range on HMM: 195-265/270.0
YDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCkDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFL
 ...|..|||||||||.||.. .  ..  . .  .. |. ...||.|..|   .|.  || .......||  
dkaePllvHcsaGvgRtGtlialDiavrlLeetkkv.dvlaiieelRkdRmalvqhpeqyeflykavveyae
subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 12-82 1.5e-15 51.8 In-house 197-266 (283) alignment 
Range on Protein: 12-82
Range on HMM: 197-266/283.0
YDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
    |.|||||.|.||... ...|  ....       |. . |. .|.||  |.||  ||. .| . ||  
skkgPivvhCstgiGrtavfiaasasvkdalte.svvdvfavvkimreqrmmavqtldqyklvhelvleqa
subfamily_PTPN3_pd Subfamily PTPN3 12-80 2.2e-14 48.0 In-house 206-273 (280) alignment 
Range on Protein: 12-80
Range on HMM: 206-273/280.0
YDTNPVVVHCSAGVGRSGTIVGISLIMDkMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
 ...|||||||||.||.| .. . . .  .|.  .   . ..| ..|.||   .||..|| ..   .|.
gkeePvvvhCsaGigrtGvlilletala.lieaaepvypldivrtmrdqramlvqtasqykfvCeailk
subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 12-77 5.5e-14 46.3 In-house 220-283 (302) alignment 
Range on Protein: 12-77
Range on HMM: 220-283/302.0
YDTNpVVVHCSAGVGRSGTIVGISLIMDKMiQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRV
| .| |.|||||||||.||.| |   ..   .  .  |. ..|  .|. |. |.|.| | .|.  .
ykkn.vlvhcsaGvGrtGtlvaikyGiqlc.skkkvtdllsivlpvrqcryGavqdeqqliylllc
subfamily_CG7180_pd Subfamily CG7180 12-84 7.2e-14 46.1 In-house 221-292 (296) alignment 
Range on Protein: 12-84
Range on HMM: 221-292/296.0
YDTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
 ...||||..| |..|||  ..|   ......  .. |. . |  .|..|   ...  .|.||  ||||..| 
peegPvvvvssdGasRsGvylaidanlelveke.eevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlc
subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 13-82 1.7e-20 68.3 In-house 215-283 (319) alignment 
Range on Protein: 13-82
Range on HMM: 215-283/319.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
.  |.|||||||||| || . .. ..... .  .  |. . | ..| ||   .|...|| .|. .|||. 
qsgPivvhCsaGvGRtGtfivldamlervkee.gvlDvfstvsrlRtqRnimvqrpeqYkfiyealleav
subfamily_PTPN9_pd Subfamily PTPN9 13-86 2.1e-20 68.0 In-house 222-294 (297) alignment 
Range on Protein: 13-86
Range on HMM: 222-294/297.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMiQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELH
.  |.|||||||.||.|| . . . .... . ..  |. . |. .|.|| ..|||. ||.. .  .||| |||.
sgPPivvhcsaGiGrtGtfitldiclsrl.eevgtvdvvetvkllrtqrafsiqtpeqyefcylavleyalelk
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 13-82 2.5e-18 61.2 In-house 174-242 (250) alignment 
Range on Protein: 13-82
Range on HMM: 174-242/250.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
...||.|.|||||||||. . |. ..... .  .  |. |... .|..|  |.....||.......|.. 
gnaPvivqCsaGvgrsGafiaidavlerlkke.kvvdvfkvikvlrkdrphavesleqyvfvyeiilkal
subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 13-88 3.5e-17 57.7 In-house 223-297 (319) alignment 
Range on Protein: 13-88
Range on HMM: 223-297/319.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKE
. ...||||||||||.|. . .  ..|.| .  .  |. ..|...|.||   .|  .||..|.  ||| .|  | .
hranivvhcsaGvGrtGvyivldvlldrmkee.kqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsd
subfamily_PTPRK_pd Subfamily PTPRK 13-82 4.3e-17 56.9 In-house 209-277 (314) alignment 
Range on Protein: 13-82
Range on HMM: 209-277/314.0
DTNPVVVHCSAGVGRSGTIVGISLIMDkMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
.  ..||||||| ||.|| . |. ..| ||.  .  |. . | ..|...   ..|| ||..|. |.||  
eaGrivvhCsaGaGrtGtfiaidivld.mieregvvdvfnavktlrsrkvnmveteeqykfiydvileac
subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 13-88 5.5e-17 57.2 In-house 187-261 (284) alignment 
Range on Protein: 13-88
Range on HMM: 187-261/284.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKE
. ...||||||||||.|. . .  ..|.| .  .  |. ..|...|.||   .|  .||..|.  ||| .|  | .
hranivvhcsagvgrtgvyivldvlldrmkee.kqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsd
subfamily_CG42327_pd Subfamily CG42327 13-82 1.1e-16 55.4 In-house 246-315 (319) alignment 
Range on Protein: 13-82
Range on HMM: 246-315/319.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
.  |.||||| ||||.|...   . . .. .  .  |. .||  .|..|  |..|  || .|..|| || 
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlseya
subfamily_PTPN14_pd Subfamily PTPN14 13-82 1.7e-16 55.1 In-house 228-296 (300) alignment 
Range on Protein: 13-82
Range on HMM: 228-296/300.0
DTNPVVVHCSAGVGRSGTIVGISLiMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
   ||.|||||||||.| ..   | . . ..  .  |.|| .. .|.|| . .|| ||| ....||..|.
skPPvlvhCsaGvGrtGvlilsdl.liatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 13-83 7.1e-16 52.4 In-house 204-277 (515) alignment 
Range on Protein: 13-83
Range on HMM: 204-277/515.0
D----TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFL
|    | |...|||||||| | .. |  .. .. .. .  |. ..|. ||..| | .||. || .|. ..||..|
dhgqythpliihcsaGvGrtGvvisidsvvahaktt.rmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 13-80 2.3e-13 44.7 In-house 227-293 (297) alignment 
Range on Protein: 13-80
Range on HMM: 227-293/297.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
   ...||||||||||| .|    |..|. ..    |.. ... .|.||   .||  |. ... . |.
rnayllvhcsaGvGrsGvvvlsdvilaklrkk.ripdvaailsilreqrarlvqtleqfellydavlk
subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 13-82 3.5e-10 34.1 In-house 209-277 (287) alignment 
Range on Protein: 13-82
Range on HMM: 209-277/287.0
DTNPVVVHCSAGVGRSGTIVGISLIMDkMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
.. |.|||...|.||||... .  ... . . .   |. . |  .|..|   .|.  |. ..   |  |.
evGPlvvhddvGiGrsGillatlvlvs.rledlGrvdvaavvirlreyraalvqavvqlrllyealvtyy
0038934 (Phosphotyrosine protein) phosphatases II 13-76 4.2e-10 35.1 In-house 114-171 (194) alignment 
Range on Protein: 13-76
Range on HMM: 114-171/194.0
DTNPVVVHCSAGVGRSGTIVGISLIMDkmiQGInckDMKKLVEEIRNQRHYAIQTEAQYMYIHR
  . |.||| ||.||.||.|.  ||.    .|.   .... .. .|  |  ||..  .. ....
pggvvaVHCkaGlgRtGtlvaaYLiyr...lgm...saeeAialfrekRpgaipnqdyleallk
subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 13-82 2e-09 31.4 In-house 270-338 (347) alignment 
Range on Protein: 13-82
Range on HMM: 270-338/347.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
  .|||| |  |. || |.|  |.|......| .  |  .|   .|.||   .     | |  |  | |.
klapvvvmcdlgldrsatvvltsiiieqvldg.ktpdcddlfkkmrdqragvftmsifytyairaalfyl
subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 13-82 8.4e-09 29.2 In-house 264-344 (349) alignment 
Range on Protein: 13-82
Range on HMM: 264-344/349.0
DTNPVVVHCSAGVGRSGTIVGISLIMD--KM----IQGINCKDMKK-----LVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
......|||||| ||.|..| . |...  ..       |. . ..|      | |.| ||   .|  ||.. |.  ||.||
qlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyf
subfamily_PTPDC1_pd Subfamily PTPDC1 13-75 2.6e-08 28.5 In-house 113-169 (182) alignment 
Range on Protein: 13-75
Range on HMM: 113-169/182.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGinckdmKKLVEEIRNQRHYAIQTEAQYMYIH
. . | ||| || || | ..   |.  | ...      .| .. .|..|  .|||  |   ..
qegkvavhChaGlGrtGvliacylvyakrlta......ekaiklvrskrpksiqtreqvelvk
ATP-grasp_2 ATP-grasp domain 13-99 1.8e-07 18.1 Pfam-A 38-117 (202) alignment 
Range on Protein: 13-99
Range on HMM: 38-117/202.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKmiqgincKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKETYEGLLLTKNY
... .|| .   .|  |   |. |. .|       ...|. ..|. ...  . ||...   ...||.|  .....|.| ...| .. 
gakelvvKaQvlaGGRGKagGvklvksk.......eevkeaakellgkklvtkqtgkegkkvekvlveeavdikrElYlaivlDras
subfamily_Cele-PTP-16_pd Subfamily Cele-PTP-16 13-84 6.8e-06 19.9 In-house 210-281 (303) alignment 
Range on Protein: 13-84
Range on HMM: 210-281/303.0
DTNPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
|..| |    .|.||.||.  .      . .  .. |. | .| .|| | .|.|  .|. ... .| |. |.
dstptvymslsgcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehvld
subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 14-82 1.5e-20 68.4 In-house 207-276 (281) alignment 
Range on Protein: 14-82
Range on HMM: 207-276/281.0
T-NPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
|  |.|.||||||||.|| ...  ..... .  .  |.| .|.|.|..| . .|| .|| ......|...
tkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 14-84 1.9e-15 51.7 In-house 217-286 (297) alignment 
Range on Protein: 14-84
Range on HMM: 217-286/297.0
TNPVVVHCSAGVGRSGTIVGISLIMDKMiQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
 .|..|||.||||| | .. |  .. .. .  .  |. .||. .|..| | .||. || ... ..||..| 
egPllvhclaGvGrtgvlltidsvvaea.krekevdifglvkklrqerpylvqtkeqykfvyvavlealls
subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 14-88 2.9e-15 51.0 In-house 212-285 (315) alignment 
Range on Protein: 14-88
Range on HMM: 212-285/315.0
TNPVVVHCSAGVGRSGTIVGISLIMDKMiQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKE
  ..||||||||||.|| . .. ..|.. .  |  |. .... .|..|  ..|. .|| .|. .||| |.     
vgaivvhcsaGvGrtGtfitldavldqa.eaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdts
subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 14-86 9.3e-15 49.2 In-house 216-287 (290) alignment 
Range on Protein: 14-86
Range on HMM: 216-287/290.0
TNPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELH
 ...|||||..||||.. . .   ..|. .     |. ..... | |.   .||. || .|....|.|. ...
ntsivvHCSdtvgrsavfcaaattinkckte.gvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfe
subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 14-84 3.6e-13 43.7 In-house 169-238 (392) alignment 
Range on Protein: 14-84
Range on HMM: 169-238/392.0
TNPVVVHCSAGVGRSGTIVGISLIMDKMiQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
| |...||||||||.| .. |  .. .  .     |. ..| .||..| | .||. || .|.  .|| .| 
thpliihcsagvgrtgvvisidsvvaha.kktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllw
subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 14-82 1.3e-12 42.1 In-house 226-293 (301) alignment 
Range on Protein: 14-82
Range on HMM: 226-293/301.0
TNPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
  |||||||..|.|||. . .|. ..         |. .... .| ..  |..|  ||. |. |. .|.
ggpvvVHCSdtVsrsGvYcsvsiglEQcka.egVVdvfqvtkavrrskpgaVtTLeqytsiydvidmyl
subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 14-80 6.1e-12 40.2 In-house 173-238 (239) alignment 
Range on Protein: 14-80
Range on HMM: 173-238/239.0
TNPVVVHCSAGVGRSGTIVGISLIMdKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
. | |.||||||||.|... |  .. .  .  .  |. . |. ||..| . .||  ||..||  .||
arpwvihcsagvgrtgaflvidaml.rqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 14-80 8.3e-12 39.8 In-house 174-239 (239) alignment 
Range on Protein: 14-80
Range on HMM: 174-239/239.0
TNPVVVHCSAGVGRSGTIVGISLIMdKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLE
. | |.||||||||.|... |  .. .  .  .  |. . |. ||..| . .||  ||..||  .||
arpwvihcsagvgrtgaflvidaml.rqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 14-84 3.7e-11 37.0 In-house 127-196 (440) alignment 
Range on Protein: 14-84
Range on HMM: 127-196/440.0
TNPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
  |..||||||.||.| |. .  |. .  .  .  |.  ... .||.|   .||  || ..| ..|| .| 
ngpllvhcsagagrtgviiavdsilreakr.sdqidifsfinsmrnnrpqmvqtpeqyafvheavlegllc
subfamily_PTEN_pd Subfamily PTEN 14-75 1.1e-08 30.3 In-house 114-173 (184) alignment 
Range on Protein: 14-75
Range on HMM: 114-173/184.0
TNPVVVHCSAGVGRSGTIVGISLIMDKMIQgiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIH
.| ||||| || ||.|...   |.  ....  . .....| .|.| . . ...  .|  |..
knvvvvHCkaGkGRtGvlivayllksllle..kaeealelfaeaRtknkkgvtiPsqrRYve
subfamily_eak_pd Subfamily eak 14-88 1.5e-06 21.8 In-house 236-311 (332) alignment 
Range on Protein: 14-88
Range on HMM: 236-311/332.0
TNPVVVHCSAGVGRSGTIVGISLIMdKMIQG--INCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLELHKE
..  .. .. |  |.|. | | |.. ..|..   |   ...|.  ....| ... .. |. .|. ..|.|.|  ...
sfapiiqsarGsaraGvfvvidlli.rlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnr
subfamily_ptpA1_pd Subfamily ptpA1 14-42 4.4e-06 20.7 In-house 229-257 (418) alignment 
Range on Protein: 14-42
Range on HMM: 229-257/418.0
TNPVVVHCSAGVGRSGTIVGISLIMDKMI
  |..|||||||||.||..   ..| |. 
nvpiivhcsagvgrtgtfctavimmkkld
subfamily_PTPRN_pd Subfamily PTPRN 15-78 3.2e-15 50.6 In-house 225-288 (297) alignment 
Range on Protein: 15-78
Range on HMM: 225-288/297.0
NPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVL
 |.|||||.|.||.|. . | |.......|..  |.   .| .|.||.  ..|..|. ..  ..
cpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltav
subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 15-94 4e-14 46.9 In-house 224-301 (310) alignment 
Range on Protein: 15-94
Range on HMM: 224-301/310.0
NPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCkDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLElHKETYEGLL
 |.|||||||..| ...| . | .||. .| .  |..... |....|   |||| ||..|.|| . .    ..|. | .|
gpcvvhcsagkdrlyvvvalklkidkldrglkv.daeevktellksraiciqtelqyliidrvriifarg.etevaekil
subfamily_PTPN23_pd Subfamily PTPN23 15-81 3.2e-13 44.1 In-house 213-279 (288) alignment 
Range on Protein: 15-81
Range on HMM: 213-279/288.0
NPVVVHCSAGVGRSGTIVGISLIMDKMIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY
 |.||||||||||.|..  .  .. .. .|    |. ..|. .|.||.. .|...|.     . ||.
tPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 15-82 1.1e-12 42.6 In-house 212-278 (287) alignment 
Range on Protein: 15-82
Range on HMM: 212-278/287.0
NPVVVHCSAGVGRSGTIVGISLIMDKMIQgINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYF
 ..|||||..||||.. . .   ..|  .     |. ..... | |.  ..|| .||..|  ..||| 
tsivvhCsdtvGrsamfcaaattinkckt.eGviDvfqvlksqriqkpgsvqtveqykfindivleyl
subfamily_Cele-PTP-4_pd Subfamily Cele-PTP-4 15-84 1.3e-10 35.2 In-house 219-287 (302) alignment 
Range on Protein: 15-84
Range on HMM: 219-287/302.0
NPVVVHCSAGVGRSGTIVGISLIMDKMIQGiNCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEYFLE
...|.    |.|| |...   . ..|. .| .   .| .|. ||.||  |...  ||. ....|| |...
entvivSknGaGRagafltlavaveklqkg.kepnikeivksiRsqRpravdslkQyvslyialllyikk
subfamily_PRL_pd Subfamily PRL 15-74 1e-07 26.1 In-house 91-142 (151) alignment 
Range on Protein: 15-74
Range on HMM: 91-142/151.0
NPVVVHCSAGVGRSGTIVGISLIMDkmiqGINCKDmkkLVEEIRNQRHYAIQTEaQYMYI
. | ||| ||.||.  .| ..|| .    |.. .|    || ||..|. || .. |  ..
stvavhcvaGlGraPvlvalaliea....Gmkyed...avefirekrrgainsk.qlkfl
subfamily_CDKN3_pd Subfamily CDKN3 15-76 7.1e-07 23.0 In-house 133-190 (202) alignment 
Range on Protein: 15-76
Range on HMM: 133-190/202.0
NPVVVHCSAGVGRSGTIVGISLIMdkMIQGINCKDMKKLVEEIRNQRhyAIQTEAQYMYIHR
.  .|||  |.|||  ..   |..  . . |. ||  . . ...  |  ||||  || |.. 
rktlvhcygglgrsslviacllly..lddtiepkdaidklrdlkgsr..aiqtvkqynylse
subfamily_Sponge-PTP-7_pd Subfamily Sponge-PTP-7 18-81 5.1e-10 33.6 In-house 2-64 (69) alignment 
Range on Protein: 18-81
Range on HMM: 2-64/69.0
VVHCSAGVGRSGTIVGISLIMDKmIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY
|||||.| ||.||.. | . | . |.     |.   |  .|  |   .  | .|..||  | | 
vvhcssgtgrtgtfiaimvemar.ikseklvdifnnvqymrkcrpmmvmneieyifihdalvea
subfamily_Sponge-PTP7_pd Subfamily Sponge-PTP7 18-81 6.4e-10 33.2 In-house 1-63 (69) alignment 
Range on Protein: 18-81
Range on HMM: 1-63/69.0
VVHCSAGVGRSGTIVGISLIMDKmIQGINCKDMKKLVEEIRNQRHYAIQTEAQYMYIHRVLLEY
|||||.| ||.|| . | . | . |.     |.   |. .|  |   .  | .||.||  | | 
vvhcssGtGrtGtfiaimvemar.ikseklvdifnnvqymrkcrpmmvmneneymfihdalvea