Synonym: CELE_F54F12.1, F54F12.1
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
| Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
|---|---|---|---|---|---|---|---|---|---|
| subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 849-1145 | 8.2e-164 | 538.3 | In-house | 7-302 (302) | alignment | ||
Range on Protein: 849-1145
Range on HMM: 7-302/302.0
LCTKSPQEWAEGIYDTIWKLDVMVSTNTQANISQRRHTLFLCEPKTMAKLVGFPDPFINANVMKFGEISWIMAQGPMDGTEHLEKISKVPPKPKKSTLEK
| .|. | .. ...||....|||....||.||..||.||||||||||.|...||||||.|..||.||||||||||||..||.||.|..||||||||
lnktlleefleyveraleklkkktstnlekdiserrkslficepktmaklvdfkndfinanvlkldeikwimaqGpmdGtekkekvskkpivpkkstlek
HWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLENFTDKKSFVMYNLEYKNDQWQDkKLKKTVSVLHFTAWPDHGAPK
|||.|.||.|.||.||.|..|....|.|.|||.|||....||||||.|.|..|.||.|||||||..|..|.||..... |.||||..|.|.|||||||||
hwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkk.kvkktvdilafsawpdhGapk
NPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMAKEGVLYWRSFDA
....||||..||||||..|||||||||||||||||||||||||.....|.|||||.|||.||.||||..|||.||..|.|||.|.|.||||.|||||
eaytaldilkfcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkglmekagvlylrsfda
|
|||||||||
| 0043336 | (Phosphotyrosine protein) phosphatases II | 865-1127 | 3.9e-47 | 156.4 | In-house | 33-273 (278) | alignment | ||
Range on Protein: 865-1127
Range on HMM: 33-273/278.0
IWklDVMVSTNTQANISQRRHTLFLCEPKTMAKLVGFP----DPFINANVMKFG--EISWIMAQGPMDGtehlekiskvppkpkksTLEKHWAVIDQYDV
. | . .. ..|.. .|.. .|. . .. || .. . .|||. ... .|..|||... |.|..| . ...|
kl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpe.................tvedFwrmvwelgv
GIVAQLASVIESDDRKFAPYYSekvGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNdqwQDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIR
.. | . | . |.|.|.. |. .|.|..|||...... .. .....|| .| .. ..|| ..|...|||||.| ... ||...
ttivmLtelvelgrvkcaqYwp...ggsltygdftvtllkeeh.......lddytvrtlevtn...lgdgesrtvthyhylgwpdhgvpeslsllldflk
FCES----YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
. . .. ||||||||||||||..|. . ... .|.. .|...|. .|..|.||||. .|...|. ..
avrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal
|
|||||||||
| 0040438 | (Phosphotyrosine protein) phosphatases II | 867-1140 | 6.8e-55 | 181.9 | In-house | 31-285 (317) | alignment | ||
Range on Protein: 867-1140
Range on HMM: 31-285/317.0
KLDVMVSTNTQANISQRRHTLFLCEPKTMAKLVGFP----DPFINANVMKFG--EISWIMAQGPMdgtehlekiskvppkpkKSTLEKHWAVIDQYDVGI
||| . .. ..|.. .|.. .|. . . || .. . .|||. ... .|..|||. ..|.|..| . ...|..
kldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPl.................pntvedFwrmvweqgvtv
VAQLASVIESDDRKFAPYYSEkvGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDqwqDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFC
. | . | ...|.|.|... ||..|.|..|||..|. . ........|| ... ... . || ..|.|.|||||.|..|| ||.....
ivmLteleelgrekcaqYwpl..getltygdftvtllseee.......lagitlrtlevedl...gdsesrtvthfhytgWpdhgvppspdllldfleav
ESY----KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMAKEGVLYW
... .. ||||||||||||||..|. . .... .|.. .. ..|. .|..| ||||. .|...|. .. . .. |. ..
realedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepa
|
|||||||||
| subfamily_PTPN13_pd | Subfamily PTPN13 | 868-1123 | 1.4e-26 | 88.4 | In-house | 26-261 (273) | alignment | ||
Range on Protein: 868-1123
Range on HMM: 26-261/273.0
LDVMVSTNTQANISQRRHTLFLCEPKTMAKLVGFPDpFINANVMKFGEiswimaqgpmdGTEHLEKISKVPPKPKksTLEKHWAVIDQYDVGIVAQLASV
|| ......| .. |. | .| || . .|||. .| | .. | | | |. | . | .. . .. ..| ...
ldtcevgkkkenkdknryrnvlPydetrvklgdegg.yinaslikvpv...........gkdeyeyiacqGPlPe..tvkdfwqmvweqkaeviamvtle
IESDDRKFAPYYSEKVGEKMTfgrytvTTKSINTKLENFTDKKSFVMYNLEYKNDQWQDkklKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYKT--
|.. | |. |. ..|.. . .. .|.. .....||. .|. |. . .. . |. |.|..||||| |.... | ... . .|
kekgkvkchrywPesknkklk......vsnrlevellkvqkldgfvvralavkdsesge...srevahlnfvkwPdhgvPssaaellqfvaevrrlqtda
-SVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYL
..||||||.||.|||..|. ..| .. .. || .|. | | ||. .| ..
gPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifv
|
|||||||||
| 0039614 | (Phosphotyrosine protein) phosphatases II | 869-1131 | 9.3e-51 | 168.4 | In-house | 47-289 (297) | alignment | ||
Range on Protein: 869-1131
Range on HMM: 47-289/297.0
DvMVSTNTQANISQRRHTLFLCEPKTMAKLVGFP-----DPFINANVMKFGEI---SWIMAQGPMDGtehlekiskvppkpkksTLEKHWAVIDQYDVGI
| .. .. ..|.. .|.. .|. . .. || ... . .|||. ... .. .|..|||... |.|..| . ...| .
d.ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpe.................tvedFwrmvweqgvtv
VAQLASVIESDDrKFAPYYSEKVGekmTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNdqwqdKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFC
. | . .| . |.|.|..|..| |.|..|||.... . .. .....|| .| .. .|| ....| |||||.| .... |......
ivmLtklvelgr.kcaqywpeegg...tygdftvtllkveh.......ldgytvrtlevtn.....ngesrtvthfqytgwpdhgvppslellleflelv
ES------YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGV
.. .. ||||||||||||||..|. . .... .|.. ..|..|. .|..| ||||. .|...|. .. . .
realaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallell
|
|||||||||
| 0046845 | (Phosphotyrosine protein) phosphatases II | 869-1132 | 4.5e-50 | 166.0 | In-house | 18-275 (284) | alignment | ||
Range on Protein: 869-1132
Range on HMM: 18-275/284.0
DVMVSTNTQANISQRRHTLFLCEPKTMAKLVGFPDP-----FINANVMKFG-------EISWIMAQGPMDGtehlekiskvppkpkksTLEKHWAVIDQY
. .. ..|.| |.. .|. .. || ... .|||. ... . .|..|||... |.|..| .. ..
lslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpn.................tvedFwrmvweq
DVGIVAQLASVIESDDRKFAPYYSEKvGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDqwQDKKLKKTVSVLHFTAWPDHGAPKNPDYALDI
.| .. | . .| . |.|.|.... ||..|.|..|||..|... |.......|| .| . .. .|| ..|.|.|||||.| .|. |..
nvrvIVmltelvengrekcaqYwple.gevltygdftvtllseev.......kddytvrtleltnl..gytgesrtvthfhytswpdhgvppspedllef
IRFCESY------KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTER---TTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVM
.|..... . ..||||||||||||..|. . ... .|. . ..|..|. .|..|.|.||. .|..... .. ..
lrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylk
|
|||||||||
| 0050432 | (Phosphotyrosine protein) phosphatases II | 871-1132 | 1.6e-53 | 177.4 | In-house | 60-300 (308) | alignment | ||
Range on Protein: 871-1132
Range on HMM: 60-300/308.0
MVSTNTQANISQRRHTLFLCEPKTMAKLvGFPDPFINANVMKFG----EISWIMAQGPMdgtehlekiskvppkpkKSTLEKHWAVIDQYDVGIVAQLAS
. ... ..|.. |.. .|. .. || . .. .|||. ... . .|..|||. ..|.|..| . ...| .. | .
ysvallpenkdkNrykdilpydhsRVkl.degsdYInAsyvdgyssklprkfIatqgPl.................pntvedFwrmvweqnvrvIvmLtk
VIESDDRKFAPYYSEKVG-EKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDQWQDKklkKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESY--
.| . |.|.|. ...| . ...|..|||..|. . ........|| .| . .. .|| ..|.|.|||||.| .|. ||........
lvengrekcaqYwplelgggsleygkftvtllseev.......lddytvrtleltnlgdges...rtvthfhytnWpdhgvPpspeilldflelvrkslp
KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVM
. ..||||||||||||..|. . ... .|.. .....|. .| .| |.||. .|...|. .. . ..
ggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylk
|
|||||||||
| 0047943 | (Phosphotyrosine protein) phosphatases II | 871-1127 | 2.1e-51 | 170.3 | In-house | 30-268 (273) | alignment | ||
Range on Protein: 871-1127
Range on HMM: 30-268/273.0
MVSTNTQANISQRRHTLFLCEPKTMAKLVGFPDPFINANVMKF--GEISWIMAQGPMdgtehlekiskvppkpkKSTLEKHWAVIDQYDVGIVAQLASVI
. .. ..|.. |.. .|. ... || . .. .|||. ... . .|..|||. ..|.|..| . ...| .. | ...
ysvallpenkdknrykdilpydhsrvklgdggsdyinAsyvdgynlkrkfiatqgPl.................pntvedfwrmvweqnvrviVmLtelv
ESDDRKFAPYYSEKVGE-KMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDQWQDkklKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCES-----
| . .|.|.|.....|| ..|.|..|||..|..| |.......|| .| . .. ..|| ..|.| |||||.| .... |..|.....
elgrekcaqYwpleggelsltygkftvtllseet.......kddytvrtleltnlgtge...srtvthfhytgwpdhgvppslesllefielvrkaleal
-YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
.. |.||||||||||||..|. . ... .|.. ..|..|. .|..|.|.||. .|...|. ..
psngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyeal
|
|||||||||
| 0045450 | (Phosphotyrosine protein) phosphatases II | 871-1127 | 2.5e-50 | 167.3 | In-house | 47-300 (307) | alignment | ||
Range on Protein: 871-1127
Range on HMM: 47-300/307.0
MVSTNTQANISQRRHTLFLCEPKTMAKLVG-----FPDPFINANVMKF----------GEISWIMAQGPMDGtehlekiskvppkpkksTLEKHWAVIDQ
. ... ..|.. .|.. .|. . | || .. .|||. ... .|..|||... |.|..| . .
ysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpe.................tvedFwrmlwe
YDVGIVAQLASVIESDDRKFAPYYSEKvGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDqwQDKKLKKTVSVLHFTAWPDHGAPKNPDYALD
..|... | . .| ...| |.|.... ||..|.|..|||..|... ........|| .. . .. || ..|.|.|||||.|.... .||
qgvtvivmltelvelgrekcaqywPde.geeltygnftvtllseeh.......ldgytvrtlevtdl..dgtgesrtvthfhytgwpdhgvppsfeelld
IIRFCES------YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERT---TNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
.|. ... .. ||||||||||||||..|. . ... .| | .||..|. .|..| ||||. .|...|. ..
fieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeal
|
|||||||||
| DSPc_SM00195 | 872-1129 | 1.9e-52 | 173.5 | In-house | 19-260 (263) | alignment | |||
Range on Protein: 872-1129
Range on HMM: 19-260/263.0
VSTNTQANISQRRHTLFLCEPKTMAKLVGF----PDPFINANVMKF--GEISWIMAQGPMdgtehlekiskvppkpkKSTLEKHWAVIDQYDVGIVAQLA
... ..| |. |.. .|. .| || .. .||||..|. . ..|..|||. .||.|..| .. . .| |.. |
teaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl.................pstvedFWrmvweekvkiivmlt
SVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLenftdkKSFVMYNLEYKNDQWqdkKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYKT
. |.. .| . |. |. |.|.|||...|.... ..| .......||..... . ...| ......|||||.|..... |...|.... |
eeeengkekcdrywpeesggketfgkisvklvevekkk......deiilrtleltkegk...eetrkvtqyqyknWpdhgvpdstksvlellravkksks
----SVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
..||||||||||||.|.|.. .. ...| . .. .||. .|. |.|.||. .|..... .| .
tssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
| PTPc_SM00194 | 872-1129 | 1.9e-52 | 173.5 | In-house | 19-260 (263) | alignment | |||
Range on Protein: 872-1129
Range on HMM: 19-260/263.0
VSTNTQANISQRRHTLFLCEPKTMAKLVGF----PDPFINANVMKF--GEISWIMAQGPMdgtehlekiskvppkpkKSTLEKHWAVIDQYDVGIVAQLA
... ..| |. |.. .|. .| || .. .||||..|. . ..|..|||. .||.|..| .. . .| |.. |
teaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPl.................pstvedFWrmvweekvkiivmlt
SVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLenftdkKSFVMYNLEYKNDQWqdkKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYKT
. |.. .| . |. |. |.|.|||...|.... ..| .......||..... . ...| ......|||||.|..... |...|.... |
eeeengkekcdrywpeesggketfgkisvklvevekkk......deiilrtleltkegk...eetrkvtqyqyknWpdhgvpdstksvlellravkksks
----SVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
..||||||||||||.|.|.. .. ...| . .. .||. .|. |.|.||. .|..... .| .
tssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaile
|
|||||||||
| 0051299 | (Phosphotyrosine protein) phosphatases II | 872-1128 | 2.4e-49 | 163.7 | In-house | 42-283 (288) | alignment | ||
Range on Protein: 872-1128
Range on HMM: 42-283/288.0
VSTNTQANISQRRHTLFLCEPKTMAKLVG----FPDPFINANVMKF--GEISWIMAQGPMDgtehlekiskvppkpkkSTLEKHWAVIDQYDVGIVAQLA
... ..|.. |.. .|. .. || .. .|||. ... . .|..|||.. .|.|..| . ...| .. |
saallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlp.................ntvedFWrmvweqnvrvIvmlt
SVIESDDRKFAPYYSEkvGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDQ-WQDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESY-
...| . .|.|.|... |...|.|..|||..|. . ........|| .| . .. .. ..|| ..|.|.|||||.| .|. ||..|.. ..
klvelgrekcaqYwpl..ggsltygditvtllseev.......lddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkal
---KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
. |.||||||||||||..|. . ... .|.. ..|..|. .|..|.|.||. .|..... ..
asgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyeall
|
|||||||||
| 0036941 | (Phosphotyrosine protein) phosphatases II | 873-1143 | 5.4e-56 | 185.4 | In-house | 33-289 (297) | alignment | ||
Range on Protein: 873-1143
Range on HMM: 33-289/297.0
STNTQANISQRRHTLFLCEPKTMAKLVGFPDPFINANVMKFGE--ISWIMAQGPMDgtehlekiskvppkpkkSTLEKHWAVIDQYDVGIVAQLASVIES
.. ..|.. |.. .|. ..|. || . .. .|||. ... . .|..|||.. .|.|..| . ...| .. | ...|
vallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlp.................ntvedFWrmvweqnvtvIvmltelvel
DDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKlenftDKKSFVMYNLEYKNDqwqDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCES------YK
. |.|.|.....|| .|.|..|||..|.... .........|| .. ... ..|| ..|.| |||||.| .|.. ||.|..... .
grekcaqywpleegesltygdftvtllsvevv.....llddytlrtlevtdt...gngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsg
TSVLVHCSAGVGRTGTLVAIKYGIQLCT---TERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMAKEGVLYWRSF
. |||||||||||.||..|. . .|. .|.. ..|..|. .|..|.||||. .|...|. .. . .. |. .......
gpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllkl
|
|||||||||
| 0040439 | (Phosphotyrosine protein) phosphatases II | 874-1127 | 4e-47 | 156.3 | In-house | 6-242 (249) | alignment | ||
Range on Protein: 874-1127
Range on HMM: 6-242/249.0
TNTQANISQRRHTLFLCEPKTMAKLVG----FPDPFINANVMKF--GEISWIMAQGPMDGtehlekiskvppkpkksTLEKHWAVIDQYDVGIVAQLASV
.. ..|.. .|.. .|. . .. || |.. .|||..... .|..|||... |.|..| . ....... | |
allpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpe.................tvedfwrmlwelgitvivmLtsl
IESDDRKFAPYYSEkvGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDqwqDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCES-----
| . |.|.|... |. ...|..|||..|... |.......|| .| .. . || ....| |||||.|.... .||.|. ...
velgrekcaqywpl..ggsleygdftvtllsvev.......kddytvrtleltnl...ydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleel
-YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
.. ||||||||||||||..|. . ... .|.. .|...|. .|..|.||||. .|...|. ..
pkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeal
|
|||||||||
| 0042113 | (Phosphotyrosine protein) phosphatases II | 875-1127 | 3.3e-45 | 149.8 | In-house | 5-239 (245) | alignment | ||
Range on Protein: 875-1127
Range on HMM: 5-239/245.0
NTQANISQRRHTLFLCEPKTMAKLVGFP----DPFINANVMKFGEI--SWIMAQGPMDGtehlekiskvppkpkksTLEKHWAVIDQYDVGIVAQLASVI
. ..|.. .| . .|. . |. || . ...|||. ... .| .|..|||... |.|..| . .... .. | .
llpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpe.................tvedfwrmlwelgittivmLteee
ESDDRKFAPYYSEkvGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDqwqDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCES-----Y
| . |.|.|... ||..|.|..|||..|... ........|| .|. .. ...| ..|.. |||||.| .... ||...|...
elgrvkcaqywpl..gesltygdftvtllseeh.......lddytvrtlevtnl...gddesrevihyhylpwpdhgvpdllellldflefvrkalaeds
KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
.. ||||||||||||||..|. . ... .|.. .| ..| .|..| ||||. .|...|. ..
ngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal
|
|||||||||
| 0037934 | (Phosphotyrosine protein) phosphatases II | 875-1127 | 2.6e-42 | 140.4 | In-house | 6-238 (243) | alignment | ||
Range on Protein: 875-1127
Range on HMM: 6-238/243.0
NTQANISQRRHTLFLCEPKTMAKLVGfpDPFINANVMKFGEiSWIMAQGPMDGTEHLekiskvppkpkksTLEKHWAVIDQYDVGIVAQLASVIESDDRK
. ..|.| .|.. .|. . .. || | . .|||| .. . .| |||...| . .|...| . ....... | . .| . |
llpenlsknrysdilpydhsrvkleg..sdyinanliyvtp.rliatqgPlpetved.............dlasfwrmlwelgitvivmltelvElgrek
FAPYYSekvGEKmTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDQWQDKKlkKTVSVLHFTAWPDHGAPKNPDYALDIIRFCE------------S
|.|.. ||. |.|..|||..|... ........|...| ...| . ..| .|...|||||.| .|. ||..... .
caqywp...gev.tygdftvtllseeh.......lddytvrtlllenldlddlt..rlvihyhylpwpdhgvPdspedlldfldevrefieellsllald
YKTSVLVHCSAGVGRTGTLVAIKYGIQLCtterTTNLLSIVCPVRNCRFG-AVQSAQQLMYLIVCI
. |||||||||||||||.|. . ..|. . .|...|. .|..|.| |||. .|...|. ..
sggpvlVHCsaGvgRtGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeal
|
|||||||||
| subfamily_PTPN3_pd | Subfamily PTPN3 | 875-1129 | 1.5e-27 | 91.2 | In-house | 37-273 (280) | alignment | ||
Range on Protein: 875-1129
Range on HMM: 37-273/280.0
NTQANISQRRHTLFLCEPKTMAKLVGFPDPFINANVMKFGeIswimaqgpmDGTEHLE-KISKvpPKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDR
. .|.|. |. | .| ||. . .|||| ... | ..|. |. | ..| .. | .. . .. .. |....|.
rkpenlsknryrdilpydatrvklkesetdyinanyvnme.i.........pstglvnryiat..qGPlaktatdfWqmvweqksslivmlttlverGrv
KFAPYYSEkVGEKMTFGRYTVTTKSIntklenfTDKKSFVMYNLEYKNDQwqdKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYK----TSVLV
| |. | ......|...|. .. .||.|. .| |. . .| .... | ..|||||| |.... |.... .... . |.|
kChqyWPe.tedeleygefsvkceke.......detksyvlrelvlkdke...tkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvv
HCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
|||||.|||| |.... ..| ... . | || .|. | ||.|.| .. .| |
hCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailk
|
|||||||||
| 0045098 | (Phosphotyrosine protein) phosphatases II | 877-1130 | 2.4e-47 | 157.0 | In-house | 31-271 (278) | alignment | ||
Range on Protein: 877-1130
Range on HMM: 31-271/278.0
QANISQRRHTLFLCEPKTMAKlvgfpDpFINANVMKFGEISWIMAQGPMDgtehlekiskvppkpkkSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFA
|.. | . .|. . .. | | .|||. ... .|..|||.. ||....| . .... .. |....| . |.|
lgnldknRykdilpydhsrVk.....d.YINAsyidgypkkfIatqgPlp.................stvadfwrmlwelgitvivmltelvelgrekca
PYYSEkvGEKMTFGRYTVTTKSINTKleNFTDKKSFVMYNLEYKNDQWQdkklKKTVSVLHFTAWPDHGAPKNP--DYALDIIRFCES------------
.|. | |. .|.|..|||..|. . . . . ..|| .. .. . .| .||.. |||||.| .| .. |....|...
qywpe..ggsltygdftvtllseevl..ddytlrtllvtnltveredle....srgvthlhylpwpdhgvpslpilksflellefirealkllaslllss
-----YKTSVLVHCSAGVGRTGTLVAIKYGIQLCttERTTNLLSIVCPVRNCRFG-AVQSAQQLMYLIVCITKG
.. |||||||||||||||||. . ..|. |.. .||..|. .|..| | |||. .|...|. .. .
lllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllel
|
|||||||||
| subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 878-1133 | 7.3e-27 | 89.1 | In-house | 42-273 (288) | alignment | ||
Range on Protein: 878-1133
Range on HMM: 42-273/288.0
ANISQRRHTLFLCEPKTMAKLVGFPDPFINANVMKfgeiswimaqgpmdGTEHLEKISkVPPKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAP
|| .. |.. . | || || .|.|||. ... ... | ..|.|. | .. . || . |. ..| .| |
anptrdryenlprcditrvklsddpdfyiaanvvs..............sakykrrli.caqaPlngtieelWkmllesdveyivmlcellekGkeksae
YYSEKVGEKMTFGRYTVTTKSINtklenfTDKKSFVMYNLEyKNDQWQDKKLkkTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGR
|. |.|||. .||. .| . .| . | | .. . ..| | .||. |.|.| |.| | .. .|.. ..||.||||||
yfPsklGekarigrlctvvkkkr......adidklvkvsll.riskegeekv..ivkilhlleWdddgvPenylsplrllevlkslqkPivvhssaGvGr
TGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMA
||||. | .. . . |.. |. || |.|. .| .|. |. . ..
tgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleelll
|
|||||||||
| subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 878-1127 | 9.4e-09 | 29.1 | In-house | 50-281 (302) | alignment | ||
Range on Protein: 878-1127
Range on HMM: 50-281/302.0
ANISQRRHTLFLCEPKTMAKLVGFPDPFINANVMKFGEISWIMaqgpmdgtehleKISKVPPKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDrKFAP
.|... ... . . ... || . || ..|| .. |.. . .. .| . .. .|. | .. | . | |. | . .
knlkknqsedvpildsnlvkleaepdsyvnaskvevPeltrsi............ilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlse
YYSEKVGEKMTFGRYTVTTKsintKLENFTDKKsfVMYNLEYKNDQWQDKKLkktVSVLHFTAWPDHGAPKNPDYALDIIRFC----ESYKTSVLVHCSA
.. .| |. ..|. | .. | |. ..| .| .| . . | ..| ..| |... |.. . . .. . ....
lfpkksgdykeygkmfvNnr....kVekaeeek..tryviEvlPegcsnsvl...anvyvltnWkqkkvpvkyaeliktaakvfakkikadentvivSkn
GVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
|.|| |.... .. ... | || .|. | ||.|..| . | ...
GaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyial
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 879-1128 | 2.3e-64 | 212.4 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 879-1128
Range on HMM: 1-234/235.0
NISQRRHTLFLCEPKTMAKLVGFPD--PFINANVM---KfGEISWIMAQGPMdgtehlekiskvppkpkKSTLEKHWAVIDQYDVGIVAQLASVIESDDR
| ...|.. .|. ||. || | .. .||||.. | . ..|..|||. |||.|..|... |..| ....|.|. |....
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgyk.ekkkfIatQgPl.................kstiedFWrmvwqekvkvivmltsleekgre
KFAPYYSEKVGEKMTFGRYTVTTKsintkLENFTDKKSFVMYNLEYKNDQWQDkkLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYK----TSVLV
|.|.|..|. .|..|.|...|..| .. .|.|......||.|...... |..|..||.|.|||||.|..|. ||.|| .|..| ..|.|
kcaqYwpeeeeesltygdikvelk.....ekekedekeytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvV
HCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
|||||||||||.||... .. ...|.....|.||. .|..|.|.|||..|...|. .|.
hCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| Y_phosphatase | Protein-tyrosine phosphatase | 879-1128 | 2.3e-64 | 212.4 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 879-1128
Range on HMM: 1-234/235.0
NISQRRHTLFLCEPKTMAKLVGFPD--PFINANVM---KfGEISWIMAQGPMdgtehlekiskvppkpkKSTLEKHWAVIDQYDVGIVAQLASVIESDDR
| ...|.. .|. ||. || | .. .||||.. | . ..|..|||. |||.|..|... |..| ....|.|. |....
nkkknRykdilpydktrvklkgsegpsdYInAnyvkgyk.ekkkfIatQgPl.................kstiedFWrmvwqekvkvivmltsleekgre
KFAPYYSEKVGEKMTFGRYTVTTKsintkLENFTDKKSFVMYNLEYKNDQWQDkkLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYK----TSVLV
|.|.|..|. .|..|.|...|..| .. .|.|......||.|...... |..|..||.|.|||||.|..|. ||.|| .|..| ..|.|
kcaqYwpeeeeesltygdikvelk.....ekekedekeytlrklelkkkkees..ekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvV
HCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
|||||||||||.||... .. ...|.....|.||. .|..|.|.|||..|...|. .|.
hCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
| 0041856 | (Phosphotyrosine protein) phosphatases II | 880-1128 | 1.3e-27 | 92.0 | In-house | 2-168 (182) | alignment | ||
Range on Protein: 880-1128
Range on HMM: 2-168/182.0
ISQRRHTLFLCEPKTMaklvgfPDPFINANVMKFGEIS--WIMAQGPMDGtehlekiskvppkpkksTLEKHWAVIDQYDVGIVAQLAsviesddrkFA-
.. .|.. .|. . .. . .||||.. .. . .|..|||... |..... . ....... |.
ldknrysdilpydhsr......dldyInanlylgslpatrfiatqgplls.................tvadflrmlkelgittivnlt.........eel
--PyysekvgekmtfgrytvttksintklenftdkksfvmynleykndqwqdKKLKKTVSVLHFTAWPDHGAPKnPDYALDIIRFCESYKTSVLVHCSAG
| ..|.... .... |||||.| .| .||.|. ... . ||||||||
ywp.................................................ellerlgiqylylpwpDhgvpd.ldelldfieevleeggpvlVHCsaG
VGRTGTLVAIKYGIQLctterTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
|||||||||. . ..| .| ..|. ||..|.|.|.. .|. .| ..
vgRtgtlvaaylmkkl.....gvsleeavklvrsrRpgmvitpnqyfflqlall
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 885-1059 | 2.4e-11 | 38.0 | In-house | 39-189 (297) | alignment | ||
Range on Protein: 885-1059
Range on HMM: 39-189/297.0
HTLFLCEPKTMAKLVGFPD--PFINANVMKFG----EISWIMAQGPMdgtehlekiskvppkpkKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPY
.. | .| || . . .|||. . | .. .|.||||. ..|.. .| .. . ||.... .| . | | |||
yrdilatddtrvkllrviterdyinadyvvfpdeeadlkyilaqGpl.................satvddfwtlvaeqdvrvivmvaklqedGrdkcapy
YSEKVGEKMTFGRYTVTTKSinTKLENFtDKKSFVMYNLEYKndqwqdkKLKKTVSVLHFTAWPDHGAPKNPDyalDIIRF
. . |.|... | . | | . ..| |. . .| |. . .. | | .||||| | . . |. ||
wpsvvqerlkagdvvvefls..stsdef.drviltelqliyr.......sesrvvrhvqflswpdhGvpsdle...dlvrf
|
|||||||||
| subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 899-1094 | 1.5e-08 | 28.4 | In-house | 86-296 (349) | alignment | ||
Range on Protein: 899-1094
Range on HMM: 86-296/349.0
VGFPDPFINANVMKFGEISWIMaqgpmdgtehlEKISKVPPKPkkSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYT--VTT
| .| .|||| .|. .|| |.. | | ||.. .. || | .| | . | . .|. |. | . .| .
sgklddyinanylkltrisvek...........kyiatqaPlP..stvddfykvillngvklvlsLnddkelslekcdiywqelsysnitvklqnsslyi
KSINTK-LENFTDKKSFVMYNLEYKNDQWQDKKLKKTVS----------VLHFTAWPDHGAPKNPDYALDIIR---------FCESY-----KTSVLVHC
... |. .|.|.. . || . .|. ..... | . |.| . || | . |.. | ...||||
anvqGnslrvstvkdtdndndnnkknCdlpddddddaillavekPyellqlqvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhc
SAGVGRTGTLVAIKYGIQ-LCTTE
||| ||||.|| . . .. | ..
saGcGrtGvlvtldlllsileplq
|
|||||||||
| subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 901-1137 | 1.8e-22 | 74.8 | In-house | 44-257 (290) | alignment | ||
Range on Protein: 901-1137
Range on HMM: 44-257/290.0
FPDPFINANVMKF-GEISWIMAQGPMDGTehlekiskvpPKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDR--K--FAPYYSEKVGEKMTFGRYTVT
| | .| || ... . |. | | . . ..||.||.| .. | | | .| . | . . | |. |.|||...|. ||
fnddyiHAnrvtcpnglrliltqsPqeki..........tekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvk
TKSINTKlENFTDKKSFVMYnleykndqwqDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCT-TE
|| .. ... .. | . |.. . || . | . ..... .|..|.. . .|| |.||| |. | .| ||. | |. |.
Ckskeke.ddvetRelvvkf..........ddeeeftvtHsllkgWnklnvqedtktllsliqkvkasktpvivHcvdGiSrsAalaaiilgyQkiaets
RTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITkgvmakegV
..| ... .|. | |..||..| . . | .
gsvkledvlkalrkqralaitsalelafvdagiv........l
|
|||||||||
| subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 905-1126 | 2.3e-25 | 84.1 | In-house | 50-259 (270) | alignment | ||
Range on Protein: 905-1126
Range on HMM: 50-259/270.0
FINANVMKfgeiswimaqgpmdGTEHLEKISKVPPKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFgrytvTTKSINTKLE
.|||| .. | .. .| |...||...| .| . | .. .. . | .| . |......||... .. |.. .
YinAnyvr..............GfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekvkl.....edgkikvlal
NFTDKKSFVMYNLEYKnDQWQDkklKKTVsVLHFTAWPDHGAPKNPD---------YALDII-RFCESYKT--SVLVHCSAGVGRTGTLVAIKYGIQLCT
. . .. ... .|. . .. . .. | ....|||||.|...| . | . |.... . .||||||||||||||.|. ....|
seekeegyiltrlrle.ekgee...rrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLe
TERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVC
... ..|.|. .|. | || .| .|
etkkvdvlaiieelRkdRmalvqhpeqyeflyka
|
|||||||||
| 0049772 | (Phosphotyrosine protein) phosphatases II | 905-1123 | 1.1e-19 | 66.8 | In-house | 74-272 (314) | alignment | ||
Range on Protein: 905-1123
Range on HMM: 74-272/314.0
FINANVMKFGeISWIMAQGpmdgtehlekiskvppkPKKSTLEKH----------WAVI--DQYDVGIVAQ---------------------LASVIESD
.|||. .. ..| .|| |.. |.. | .. ....| .. | .. .
yinasyvdgf.lkfIatqg.................pleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsrLdaAlgKtpllildgng
drkfapyysekvgeK---------MTfgrytvttksintklenftdkksfvmynleykNDQWQDKKLKKTVSVLHFTAWPDHGAPkNPDYALDIIRFCES
. . .. ........ .. . .||..|| ... .....|.|.
..............neptaadlellk................................eelydpelferlgikylripvpDgsap.lledfdeflefiee
--YKTSVLVHCSAGVGRTGTLVAIKYGIQLCtterTTNLLSIVCPVRNCRF-----GAVQSAQQLMYL
.. |||||.||.|||||.|.. | . |. .| .. ||..|. |.... .|. .
adkggpvlvHCkaGkgRtgtfvvaaylmkll....gvsleealedvrlkRpinpnpgfieqleqyefi
|
|||||||||
| 0043147 | (Phosphotyrosine protein) phosphatases II | 918-1124 | 1.7e-26 | 88.4 | In-house | 22-154 (172) | alignment | ||
Range on Protein: 918-1124
Range on HMM: 22-154/172.0
WIMAQGPmdgtehlekiskvppkpKKSTLEKHWAVIDQYDVGIVAQLASViesddrkfapyysekvgekmtfgrytvttksintklenftdkksfvmynl
.|. ||| .||...|. . ....... | .
fiatqgp.................lrntladfwrmlkelgithivnltel..................................................
eykndQWQDKKLKKTVSVLHFTAWPDHGAPkNPDYALDIIRFCES-----YKTSVLVHCSAGVGRTGTLVAIKYGIqlctteRTTNLLSIVCPVRNCRFG
. ..|.... .... |||||.| .... |....|... . |||||||||||||||||. . . . .|. .|. ||..|.|
.....lydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpg
AVQSAQQLMYLI
|||. .|...|
avqnpsqyrfly
|
|||||||||
| 0036282 | (Phosphotyrosine protein) phosphatases II | 919-1124 | 6.5e-26 | 86.5 | In-house | 20-163 (174) | alignment | ||
Range on Protein: 919-1124
Range on HMM: 20-163/174.0
IMAQGPMDgtehlekiskvppkpkkstlekHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEkvgekmtfgrytvttksintklenftdkksfvmynle
| |||.. .|. . .... .| .| . .| . |. |..|
iagqgpla......................fwemlkelgittvvmlleekelglykcinywpe.....................................
ykndqwQDKKLKKTVSVLHFTAWPDHGAPKNPDyALDIIRFCESY-----KTSVLVHCSAGVGRTGTLVAIKYGIQLCTtERTTNLLSIVCPVRNCRFGA
. |.... .... |||||.| . |....|.|.. . |||||||||||||||||. . ... |.. . |..| .|..| |.
......lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgm
VQSAQQLMYLI
||. .|...|
vqtpsQyrfly
|
|||||||||
| subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 925-1137 | 5.2e-24 | 79.7 | In-house | 69-275 (285) | alignment | ||
Range on Protein: 925-1137
Range on HMM: 69-275/285.0
MDGTEHLEKISKVPPKPkkSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLENFTDKKSFVMYNLEyknDQW
| | .. |. | | || | .| | . | |....| | | || ||.|| . ||.| .| . . | ... . | | |
mpgkdqstyittqgplp..etlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgevvkfgkyeitlteckeeaiagtilnaltvinte...das
QDKKLKKTVSVlhfTAWPDHGAPKNPDYALDIIRFCE---SYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLM
. . | | |||. ||.. ... .. . .. . |||||||||| |.| | | . ..| || .| || |||| |..
seplymnhvqv...pwwpdqlapedarpmielykwvkkvnpkekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqfl
YLIVCITKGVMaKEGV
.| | . . .. |||
flyvvlmeyfi.gegv
|
|||||||||
| subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 928-1129 | 1.8e-16 | 55.0 | In-house | 22-219 (255) | alignment | ||
Range on Protein: 928-1129
Range on HMM: 22-219/255.0
TEHLEKISKVPPKPKKS-TLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSintklenftDKKSFVMYNLEYKNdQWQD
|||.. .. | | |..| . .| | . |. |. | . | |. . ||. . .||| |. || . .
tehvkPekdkkrknlysltvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttk.........ssadvvlrtleits.tlge
KKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESYkTSVLVHCSAGVGRTGTLVAIKYGIQ-----LCTTErTT--NLLSIVCPVRNCRFGAVQSAQQ
|| .|| ... |... ||... | |.. ||.||||.|.||. ..| . . | | ||| |. . ||.. .|. | .|.. |
kkkthtvkhysykGWieknaPelareilnilkvvrds.ksvvvhCstGiGrsaafvlaelvyqkmirsldtte.tveldylslleelrskrkraihtPlq
LMYLIVCITK
| . |. . .
lafsilmvld
|
|||||||||
| subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 938-1128 | 6e-18 | 59.5 | In-house | 96-276 (439) | alignment | ||
Range on Protein: 938-1128
Range on HMM: 96-276/439.0
PPKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDrkfapYYSEkvGEKMTFGRYTVTTKsINTKLENFTDkKSFVMYNleyKNDQwqDKKlKKTVSVLH
. ||| | .. | .. . . . .|. ..|| |. ... .| .| . | .| |.. . | ..| . |. .| ..|| .|
tqgpkkettddfwrlviekktvtivmltnlvesyk.....ywps..daevcygdiavrvd.rnielpnyvi.rgfkvfn...erdt..tek.ertvlqfh
FTAWPDHGAPKNPDYALDIIRFCESYK-----TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
..||||. | . . || .| .| . |.||||||||||||..|. .. .| .. || .|. | ||. | ... ..
yiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavl
|
|||||||||
| subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 939-1125 | 1.9e-23 | 77.6 | In-house | 96-275 (301) | alignment | ||
Range on Protein: 939-1125
Range on HMM: 96-275/301.0
PKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLENFTDKKSFVMynleyKnDQwQDKKLKKTVSVLHF
| |.| | ||.. |||| .. |. .| .| . |.. |..||. ||.....|. .. |.. . |... . . | .| .|| .
qgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlev.....e.ds.tgkfatrtvthyqy
TAWPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIV
. |.|.| || |.. . . ..||||||.||. .... .| . ...| .| . .|. |. .|| .|| .. .
sewtdrgvPkshaelfdlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsqlywmtl
|
|||||||||
| subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 939-1128 | 4.2e-18 | 60.1 | In-house | 91-290 (301) | alignment | ||
Range on Protein: 939-1128
Range on HMM: 91-290/301.0
PKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSiNTKLENFTDKKSFVMYNLEYK----NDQW--QDKKLKKT
| |.|| | .| |. . . .. |. | |... |. .|| ||| .. .. . .|. .. |. . . . .. . .| ..
qgpmkktlvdfWrliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvn.eqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswd
VSVLHFTAWPDHGAPKNPDYALDI-----IRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
| |. | ||..| ..| | . .| . |.||||..|.|.|. ... |. | | .. .. || . |||. .| . . |
vlqlqvtdWpqdGvvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvi
T
.
d
|
|||||||||
| subfamily_PTPRK_pd | Subfamily PTPRK | 939-1144 | 4.4e-18 | 60.2 | In-house | 92-290 (314) | alignment | ||
Range on Protein: 939-1144
Range on HMM: 92-290/314.0
PKPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvgeKMTFGRYTVTTKSINTKLENFtdKKSFVMYNleykndQWQDKKLKKTVSVLHF
.|...|.. | .. ... . |. ..| | |. |. ...| |. . ... | .. | ... . .. ...| ..|
qgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPed...tevygdikvelvetellaelv..vrifrvek......largqeeirevrqfqf
TAWPDHGAPKNPDYALDIIRFCESYK----TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMAK
..||||. |.. |...| .. . ..|||||| ||||| .||. ... .|.. .. .| .|. . |. .| ... | ...
lgWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcg
EGVLYWRSFD
| . |
etaipvsefk
|
|||||||||
| subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 940-1124 | 1.3e-29 | 98.3 | In-house | 96-276 (305) | alignment | ||
Range on Protein: 940-1124
Range on HMM: 96-276/305.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYKNDQWqdKKLKKTVSVLHFT
| |.|.. | .| .. | . .|. ..| .. | |. |...||. ||...|. || .| . ... .|. ... .| ..||. ...|
gPlkntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksekt.......asdyieRklkisiede..dkesrtvlqyqlt
AWPDHGAPKNPDYALDIIRFC-ESYKT----SVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
||||| |. . |..|. ...| ..||||||||||||. .|.. .. . .| . .. .. .|. | ..||. .| ..|
dWPdhGvpqfatsllslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflh
|
|||||||||
| subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 940-1124 | 4.5e-25 | 83.3 | In-house | 89-270 (307) | alignment | ||
Range on Protein: 940-1124
Range on HMM: 89-270/307.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLENFTDKKSFVmyNLEYKNDQWQDKklKKTVSVLHFT
|...| . ||.. | .| | |. ||| | |. . |.|..|| . | | .... . .. |. . .| .| .|.. | ..
gplentqysfwamaiqekvesvimlckvielakikceqywpleegqklvfgeapntisvanlgakklapdedli..nvttlkvdwaqk..srtiqhlqwe
AWPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGI-QLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
|||.|.|. |.... . . |.|||||||||.||.||| . .. . . .. .| .|. | |.|. | .||
nwpdrgvpqinltainlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylh
|
|||||||||
| subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 940-1128 | 6.2e-25 | 83.0 | In-house | 106-287 (298) | alignment | ||
Range on Protein: 940-1128
Range on HMM: 106-287/298.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvgEKMTFGRYTVttksintKLENFTDKKSFVMYNLEYKNDQWQdkkLKKTVSVLHFT
.| ..|.| | .. ..|.| . | .. |.| |. |. .. .| |.|. || .| . .. ... .|. .. . . ...| ||||
aPltetvedFWrmvteedigtiVmltnleeldktkyhkywPde..gketygeitv.......sllskeefadlivrklkvskkkee...kerevrqlhft
AWPDHGAPKNPDYALDIIRFCESYK-----TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
|||.|.|.| ||..| . .. ..|.|.|||||||.|| .||. .. .|.. .. .| .|. | ||||. .| ... .
sWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavl
|
|||||||||
| subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 940-1128 | 8.1e-25 | 81.9 | In-house | 93-273 (515) | alignment | ||
Range on Protein: 940-1128
Range on HMM: 93-273/515.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLENFtdKKSFVMYnleyKNDQwqdkklKKTVSVLHFT
|.|.... | .. |..| .| .. |.| | . |. .| |. . || . | . |... . |. . . |.|. .|| |||
gPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggi..krkltvl....kgdd......srtvtqfhft
AWPDHGAPKNPDYALDIIRFCES----YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
|||.|.||. | .|. . |. ....|||||||||| ...|. . | |. ... .| .|. | || .| .. .
eWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavl
|
|||||||||
| subfamily_PTPRG_pd | Subfamily PTPRG | 940-1152 | 3.1e-24 | 80.1 | In-house | 98-311 (563) | alignment | ||
Range on Protein: 940-1152
Range on HMM: 98-311/563.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEkvGEKMTFGRYTVTTKSINTKleNFTDKKSFVMYNLEYKNDQWqdKKLKKTVSVLHFT
.| |.|.. | .| . | |. .. . |. || |. . | .|.| .|| .. ... ....|. ||. |. . .. .|.| |.|
gplkdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk..desetygalqvtlieeevl..alytvrtlviknlklkkkkq..cdteklvrqyhyt
AWPDHGAPKNPDYALDIIRFCESYKTS----VLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMAKE
|||||.|. . . | .. . . . ..||||||||||||..... .. .| . |.. .. .| | ||. | ..| . . ...||
kWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiaske
GVLYWRSFDA---ITYYHEQ
| .. .| | ||
tellaeqveelknctpyleq
|
|||||||||
| subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 940-1129 | 2.7e-23 | 77.5 | In-house | 59-240 (250) | alignment | ||
Range on Protein: 940-1129
Range on HMM: 59-240/250.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRkFAPYYSEKVgeKMTFGRYTVTTKSIntklENFTDkksFVMYNLEYKNDQwqdKKLKKTVSVLHFT
.| ..|.|. | .. ....| . |... ||. . |. .. ..| ||. .| |.|.| ... .| . . |. ...| |||.
gPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvek..aekyGdvtvsllsk....eefad...ytkrklklskak...kaderivrqlhfv
AWPDHGAPKNPDYALDIIRFCESYKTS-----VLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
.||| | |.. .|.... .. . |.|.|||||||.|. .||. .. .|.. .. .. .|. | .||.| .| ... | |
vWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilk
|
|||||||||
| subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 940-1130 | 2.7e-23 | 77.3 | In-house | 94-276 (315) | alignment | ||
Range on Protein: 940-1130
Range on HMM: 94-276/315.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLENFTdKKSfVMYNleykNDQwqdkklKKTVSVLHFT
|.|.... | .. |..| .. .. |.| | . |. .. .. . || . |.. |... . . .| |. . .. ..||. .||
gPlkasvddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgva.rkl.vtrk....see......srtvtqfqft
AWPDHGAPKNPDYALDIIRFCE----SYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKG
|||.|..|. | .|. ... |.|||||||||||| ...|. .. .|. ... .| .|. | ||. .. .. . .
ewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavled
|
|||||||||
| subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 940-1135 | 9.4e-23 | 75.8 | In-house | 99-288 (297) | alignment | ||
Range on Protein: 940-1135
Range on HMM: 99-288/297.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDrKFAPYYSEKVgeKMTFGRYTVTTKSINtklenftDKKSFVMYNLEYKNDqwqDKKLKKTVSVLHFT
.|.|.|.. ||.. ...| ... |. |.|. | | |.|.| .||| .|...|.. ... |. .|| ... . | .. | .|.
mPmkatvadfWamvldeqvstivmlnddnerdk.kcaryWsdkg..vttfGdvsvvllsvs.......ereGfikrelevtkg...kakarrvvkqyqfv
AWPDHGAPK--NPDYALDIIRFC-ESYK----TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVM
|||. .. . . |..| .... . .||||.||||||| |..|. . | . ... .| .|. | || .| .. | . . ..
eWPdkaverkdsassllklisevrkdfsqnaegPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleall
AKE
...
sed
|
|||||||||
| subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 940-1129 | 2.2e-21 | 71.3 | In-house | 98-281 (319) | alignment | ||
Range on Protein: 940-1129
Range on HMM: 98-281/319.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvgEKMTFGRYTVTTKSiNTKLENFTDKKsfvmYNLEYKNDQWQDkklkKTVSVLHFT
|.. |.| | .. .... || |. . | . |. |..|. . ...||..|| .. . .||.. .| .|. |... . ..|. ..|
aPlentiedfWrmvWeeessivvmltklveklkvklkkywpee..nfeeyGrlivtlee.eeeledyiirk....lklnkkssevet....Revkhfqyt
AWPDHGAPKNPDYALDIIRFCESYKT-----SVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
.||||. |.. ||... . . . |||||||||||| .... .. | . .. |.| .| | || .| .. . .
eWpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealle
|
|||||||||
| subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 940-1137 | 6.8e-19 | 63.3 | In-house | 111-298 (319) | alignment | ||
Range on Protein: 940-1137
Range on HMM: 111-298/319.0
KPKKSTLEKHWAVIDQYDVGIVAQLAsviesdDRKFAPYYSEKVGEKmtFGRYTVTTKSINTKLEnftdkksFVMYNLEYKNDQwqDKKLKKTVSVLHFT
|.. ||. | .| .|.. . |. | . |. |. .| .|. | .|.. | .|. ..| .| .| .. . ||
GPldntladfWrmiweyncstivllt......kdkcsqywplkivik..eerfkvkvdsveetae.......yvvrdielsedg..kekdirkitqfhfl
AWPDHGAPKNPDYALDIIRF------CESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKG-VM
|||.| |. | . ... | .....|||||||||||. .... .. |. .. .| .|. | ||. | ... . . . ..
GwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlf
AKEGV
.. |
ghsdv
|
|||||||||
| subfamily_PTPN14_pd | Subfamily PTPN14 | 940-1124 | 1e-16 | 55.8 | In-house | 100-289 (300) | alignment | ||
Range on Protein: 940-1124
Range on HMM: 100-289/300.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEK--VGEKMTFGRYTVTTKSINTKLENFTDKksFVMYNLEykndqwqdKKLKKTVSVLH
| . |....| .. . .| ....|.. .|. | |. .. ....||.. |||| .. | . . .. | | ..|| |
gPleltvqdfWqmvWeqgvqlivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittg..lklkhlp........skeertvwhlq
FTAWPDHGAPKNPDYALDIIRFCESYK-------------TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
.| ||||| |.... |. .. .| . ||||||||||||| |. |. .... .. ... .|. | ||. | ..
ytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvY
|
|||||||||
| subfamily_PTPRN_pd | Subfamily PTPRN | 940-1132 | 1.8e-16 | 54.7 | In-house | 107-293 (297) | alignment | ||
Range on Protein: 940-1132
Range on HMM: 107-293/297.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvGEKmTFGRYTVTTKSINTKLENFTdKKSFVMYNLEYKNdqwqdkklKKTVSVLHFT
| ||. . | .. . | .. .|... |.. .. . |. .. |.. ... | | | ... .|| . ||. .. .||. .||
gplastvadfwqmvweqGvvvivnltrleeegvkqckrywpde.Gse.vyhiyevhlvsehiwcddyl.vrsfylknlqtse........trtvtqfhfl
AWPDHGAPKNPDYALDIIRFC-ESYK---TSVLVHCSAGVGRTGTLVAIKYGI-QLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVM
.||..|.| .. |. | ||. ....||||.|.||||. ..| . .| . .. . . .|. | | |.. .|. . . .... |
swpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaeevn
|
|||||||||
| subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 940-1125 | 2.4e-16 | 54.2 | In-house | 88-264 (281) | alignment | ||
Range on Protein: 940-1125
Range on HMM: 88-264/281.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTtksintkLENFTDKKSFVMYNLEYKNDQwqDkklKKTVSVLHFT
||| | | .| | . . |. ..|.. | | |. . . | ...|. |. | .||.| |. . . . .. .
gpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahcclqfdklsvs.......yedstvnkslvttrlnlsyeg..e...trlithwlwk
AWPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTT-NLLSIVCPVRN-CRFGAVQSAQQLMYLI-V
||| |. . | |.| . | ..||||||||.|||.|.. .| . | .. || .| | .||. || | . |
ewpdwqvpessevmlkilrkirarstppvihcsagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkv
|
|||||||||
| subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 940-1133 | 3.6e-16 | 53.6 | In-house | 95-238 (392) | alignment | ||
Range on Protein: 940-1133
Range on HMM: 95-238/392.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDdrkfapyysekvgekmtfgrytvttksintklenftdkksfvmynleykndqwqDKKLKKTVSVLHFT
|. ..|. | .. | .| .| .. . | | . ..||. |||
gpnaaslddfwrmvfqenvttiamvtklkegd......................................................kgddartvaqfhft
AWPDHGAPKNPDYALDIIRFCE----SYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMA
|||.. || | .|. . .| ...|||||||||| ...| . . . | ... .| .|. | ||. .| .. .. . ..
ewPdkdvpkhtssllkfikevkadfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllw
|
|||||||||
| subfamily_CG7180_pd | Subfamily CG7180 | 940-1133 | 4.3e-15 | 50.1 | In-house | 92-292 (296) | alignment | ||
Range on Protein: 940-1133
Range on HMM: 92-292/296.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDrKFAPYYSEKVgeKMTFGRYTVTTKSInTKLENFTDKKSFVMYN-LEYKNDQWQDKKLKKTVSVLHF
|||.|....| .. . .. | |. . . .. |. .| | .| | . . .. |.. .. .. . . . . | | ...| ....
apkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks..keqygeifveivee.kqyanlkirtfkltkkivalteqekqvkaetRivklfql
TAWPD-HGAPKNPDYALDIIRFCESYKTSV---------LVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
| |. . | ....| .... | .|..| |..|.| .|| ..| | .. | .|. | . |.. .. .|. .
teWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvll
KGVMA
. |..
eavlc
|
|||||||||
| subfamily_hpo-7_pd | Subfamily hpo-7 | 940-1132 | 3.5e-14 | 47.3 | In-house | 37-228 (263) | alignment | ||
Range on Protein: 940-1132
Range on HMM: 37-228/263.0
KPKKS----TLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTklenftdkkSFVMYNLEYKNDqWQDKKLKKTVSV
| | |..| . | | |. |. | . | |. . ||. . .|.| . .. || . ..|| .||
knlysllvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs.........dvllktlellst.lgeKkkthtvkh
LHFTAWPDHGAPKNPDYALDIIRFCESYkTSVLVHCSAGVGRTGTLVAIKYGIQ----LCTTERTT--NLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
.. |... .|... | |.. |. ||||.|.||. . . | | |. . ||.. .|. | .|.. || . |. . .
ysykgWiekndpelareilnilkvarns.kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLd
GVM
|.
fvl
|
|||||||||
| subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 940-1123 | 5.1e-14 | 46.8 | In-house | 82-258 (283) | alignment | ||
Range on Protein: 940-1123
Range on HMM: 82-258/283.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEkmTFGRYTVTTKSINTKlENFTDKKSFVMYNleykndqwqdKK-----LkktVS
| . | | .. . .. . |. . | . | . |. .. | .| .||| . |. . |. |. . .| | ..
sPldrtvvdfWkmvfdekitaivmltklqedlrikCsqyWPkrGse..dyGeftvtlrketts.nsfiikelllrvn..........ssakstll...la
VLHFTAWPDH--GAPKNPD--YALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYL
. | . .|. | . . | || |. ..||||.|.|||....|. .. || .. ..| .|. | .|||. .| . .
hyqvidWleygeqaiinslvkfnkvislqteskkgPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklv
|
|||||||||
| subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 940-1124 | 5.7e-14 | 46.9 | In-house | 52-232 (237) | alignment | ||
Range on Protein: 940-1124
Range on HMM: 52-232/237.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEkVGEKMTFGRYTVTTKsintKLENFTDKKSFVMyNLeykNDQWQDKKLKkTVSVLHFT
| .|. . | .. | .. |. .||... | |. . . ..| .||. | | |.|.| . | ... |... . .||
gplesscddfwqmvwqekcsvivmltgliegnelkchkywps.tdqpaaygvltvslk....kkeefsdytvrsl.ll...skrltlkevr.lihqyqft
AWPDHGAPKNPDYAL----DIIRFCES--YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
.|||.| |.. | .|| . . ..|||||||||| .. | .. . .. .. | . . | .|. .| ...
swpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfih
|
|||||||||
| subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 940-1086 | 3.7e-10 | 34.1 | In-house | 111-284 (350) | alignment | ||
Range on Protein: 940-1086
Range on HMM: 111-284/350.0
KPKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFG---RYTVTTKSINTKLENFTDKKSFV-MYNL---EYKNDQWQDKKLKKT
| .||... . || . .| .. |.| .| . .|. |. | ...| .. .. .. | . || .. | . .|. . ... .
aPlpstvddfykvillnkvkvilsltsdvelnlekcyrYWqegsydditvklaskwenimgindsslysadvkkeasdndnisddndlkdnnsltaitla
V------SVLHFTAWPDHGAPKNPDYALDIIR---------FCESYK-----TSVLVHCSAGVGRTGTLVAIKY
. |.. |.| . || | .. |.||. ...|||||||||||||||.. .
asdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDs
|
|||||||||
| subfamily_PTPN12_pd | Subfamily PTPN12 | 941-1131 | 5e-33 | 109.2 | In-house | 91-277 (290) | alignment | ||
Range on Protein: 941-1131
Range on HMM: 91-277/290.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSintklENFTDKKsFVMYNLEYKNDqwqdkKLKKTVSVLHFTA
| ||. .| .|....| || . ..| . | . |..|...|...|| ..||... |. .|. |.. |. ... | ...| .|.||
PLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpeegeeelefgefevtlee.....ekavddd.flirtLkveaq.....kesrkvyqfhYta
WPDHGAPKNPDYALDIIRFCESYKT----SVLVHCSAGVGRTGTLVAIKYGIQLCTTERT---TNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGV
||||| |.... |..|. ..... ..||||||||||||..|| | .| .|.. .. ..| .|. | .||. .| .. .... |
WPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
| subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 941-1127 | 2.3e-30 | 100.2 | In-house | 102-279 (290) | alignment | ||
Range on Protein: 941-1127
Range on HMM: 102-279/290.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKlENFTDKKSFVMYNleykNDQWQDKKLKKtvsvLHFTA
. |.| | .. | .| . | .|| | ..|| || || .||| .||. ..| .. . || . . . |. ...|||. |. .
alkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGeitvlcseeddk.daniikktlsvrd....kdsGkehklkh....lkiks
WPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
|||. .. | ..| | ||||||.|||||.|||. |.|. . . .|| .| .||.| ..|| | . |. .
wpdksvalstlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveil
|
|||||||||
| subfamily_PTPRD_pd | Subfamily PTPRD | 941-1129 | 1.8e-28 | 94.5 | In-house | 99-279 (564) | alignment | ||
Range on Protein: 941-1129
Range on HMM: 99-279/564.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvGeKMTFGRYTVTTKSiNTKLENFTDKKSFVmYNLEykndqwqdKKLKKTVSVLHFTA
|...|.| | . .... .. | .. |.. |.. |. || | . |.|..||| .. ...|.... .. .. . . .. ...| |||.
PlaetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.g.tetygeltVtlee.eeeladyeirtfkl.kkkk........ssesreVrqFhFts
WPDHGAPKNPDYALDIIRFCESYK----TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
|||||.|... ||.|| ..... ..|||||||||||| ..|.. .. ..|.| .. ..| .|. | ||. .| ... | .
WPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheaile
|
|||||||||
| subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 941-1124 | 1.5e-27 | 91.3 | In-house | 99-276 (290) | alignment | ||
Range on Protein: 941-1124
Range on HMM: 99-276/290.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvGEKMtFGRYTVTTksintklENFTDKKSFVMYNLEYKNDQWQdkKLKKTVSVLHFTA
| ..|| . | .|.| .| |. | ..||.. | |.... . |. .| .... | . .... .|| ||.. . . |..| ...|.
pvsntlvdFWkliwqekvtiivmltniieegkvkCqqYWpds.dtka.ygefsikl.......lneetlneyierklevknknsa..gakqsvtqyqitn
WPDHGAPKNPDYALDIIRFCES-----YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
|...| .|| | .|. . .||..||||..|||.....|.. .|. | || ...... | .. | ||..||. ...
wdstgkvtnpqtillvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgif
|
|||||||||
| subfamily_PTPRB_pd | Subfamily PTPRB | 941-1133 | 8e-27 | 89.0 | In-house | 102-287 (293) | alignment | ||
Range on Protein: 941-1133
Range on HMM: 102-287/293.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvGEKMTFGRYTVTTKSintklenFTDKKSFVMYNLEYKNdqwqdKKLKKTVSVLHFTA
| .|... | .. . . |. | ..| | |. .. | ...| .|| .. .... .|. .|. .. .| ...| .|||.
PlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPad.eepvlyGdikvtlva.......eeeledwvirelkiek.....ekeerkvrqyhfts
WPDHGAPKNPDYALDIIRFCESYK------TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMA
||||| |.... ||..| .... . ..||||||||||||..|.. .| ..| . ....||. .|. |. ||. .| ... |. . ..
WpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrk
|
|||||||||
| subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 941-1129 | 9.2e-26 | 85.5 | In-house | 98-277 (288) | alignment | ||
Range on Protein: 941-1129
Range on HMM: 98-277/288.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvGEKMTFGRYTVTTKSINTkLENFTDKKSFVMynleykndqwqDKKLKKTVSVLHFTA
| .|... | .. .... .. |....| ...| |. .. ... .| ||| .. .. ||.|. .| . || . .. ....|
PladtvndfWelvyenktstivmltelveggktkCeeYWPda.dkpknyGsvtvtlveske.ledfvlrkllle...........kkkteleitqyqyla
WPDHGAPKNPDYALDIIRFCESYKTS----VLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
||||| |.. |...| . ... ..|||||||||||| .|.. |. .| . .....|. .|. |. || .| ... .. .
WpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevlls
|
|||||||||
| subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 941-1124 | 9.1e-25 | 82.3 | In-house | 81-261 (274) | alignment | ||
Range on Protein: 941-1124
Range on HMM: 81-261/274.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMT--FGRYTVTTKSINTKlENFTDKKSFVMYNLEYKNdqwqdkklkktVSVLHF
| .|.. | .| | .| .. |. . |.. .| | |. .. . ... .| .....|... .... .| . | . .. | .
PlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyeiserygdveikvekiver.ndysvrklvlkylerers...........vkhywy
TAWPDHGAPKNPDYALDIIRFCESYK-------TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
|.|||| .|.... ||... |. . ..|.||||||.|||| .||. ... | . ..|.||| .| | | ||...| ..
tdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelih
|
|||||||||
| subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 941-1126 | 2e-24 | 81.1 | In-house | 94-273 (287) | alignment | ||
Range on Protein: 941-1126
Range on HMM: 94-273/287.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGekMTFGRYTVTtksintkLENFTDKKSFVMYNLEYKNDQWQDKklKKTVSVLHFTA
| .|. . | .||. | .. |. |.|... |..|. ...| |... | | . ...... .|| ||.. ... |..| ..|.
PmfntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeks..vvlGeynie.......llneevnagyierklevknknkagd..kqqvkqyqitn
WPDHGAPKNPDYALDIIRF--C---ESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVC
|...| ..| | .| . .||..||||..|||.....|. .|. | || . ...... | . |.|| ..| ....
WdstgkvtepqtillvieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindi
|
|||||||||
| subfamily_PTPRA_pd | Subfamily PTPRA | 941-1123 | 2.2e-24 | 80.9 | In-house | 109-287 (330) | alignment | ||
Range on Protein: 941-1123
Range on HMM: 109-287/330.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvGeKMTFGRYTVTTKSiNTKLENFTDKKSFVMyNLeykNDQwQDKKLKKTVSVLHFTA
||. |.| | .| ... . |. . | .. | | |. .. | .|.| .|. . .| |...| .| | .| .|. ...| .. |. .|||.
PkeetvedfwrmiweqksativmltelkerkeekcaqywPde.G.lvtyGnirveved.etvlvdytvrkflvq.ql...pda.trekksrlvrqfhfts
WPDHGAPKNPDYALDIIRFCES----YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYL
||| | | .| |.... .. . .. ||||||||||||..... .. .|| .. .| .|. | ||. .| ..
wPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefi
|
|||||||||
| 0049260 | (Phosphotyrosine protein) phosphatases II | 941-1124 | 2.6e-24 | 81.1 | In-house | 17-143 (152) | alignment | ||
Range on Protein: 941-1124
Range on HMM: 17-143/152.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYsekvgekmtfgrytvttksintklenftdkksfvmynleykndqwqdkklkktvsVLHFTA
| ||...| . ....... | . | . |.. |. ...
pgpntladfwrmlkelgittivmltellelgklkceqyi.......................................................qylhlp
WPDHGAPKNPDYALDIIRF----CESYKTSVLVHCSAGVGRTGTLVAIKYGIqlctteRTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
|||||.|..... |....| ... . |||||||||||||||||. . . . .|. .| ||..| |||.. .||..|
wpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrfly
|
|||||||||
| 0046846 | (Phosphotyrosine protein) phosphatases II | 941-1127 | 4.2e-24 | 80.7 | In-house | 31-169 (176) | alignment | ||
Range on Protein: 941-1127
Range on HMM: 31-169/176.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMtfgrytvttksintklenftdkksfvmynleykndqwqdkklkktvsVLHFTA
| .||.. .. . ......| | . .| . |.. |..| .... ...
plprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi...............................................qylhlp
WPDHGAPKNpDYALDIIRFCESYK---TSVLVHCSAGVGRTGTLVAIKygiqLCTTERTTNLLSIVCPVRNCRF-GAVQSAQQLMYLIVCI
|||||.| .. |....|.... ||||||||.||||||||. |. .|. ... ... ||..|. ||||. .|. .| ..
wpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgavqtpeQyrflyefe
|
|||||||||
| subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 941-1129 | 2.2e-23 | 77.7 | In-house | 92-274 (281) | alignment | ||
Range on Protein: 941-1129
Range on HMM: 92-274/281.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVgEKMTFGRYTVTTKSINtklenftDKKSFVMYNLEYKNDQWQdkklKKTVSVLHFTA
| ..|.. | .. ...| ... .. ||.. | |. .. .....| .||.... . .|.... ... .... . ...|. |..||
PvPaslvafWqmvweqkvsaivmvtreieagklkChrYWPddn.selkygdvtvkstaee.......ekatyierkfkleresge....treveqlayta
WPDHGAPKNPDYALD----IIRFCESYK-TSVLVHCSAGVGRTGTLVAIKYGIQLCTTE-RTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
|||||.|... |. . .. |. . .....||||||||||| .|. .. ...| ..... .| .|. | ||. | .. . .
WPdhGvPattkellefrkevlkltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavld
|
|||||||||
| subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 941-1131 | 4.1e-23 | 76.9 | In-house | 97-280 (318) | alignment | ||
Range on Protein: 941-1131
Range on HMM: 97-280/318.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvgEKMTFGRYTVTtksintkLENFTDKKSFVMYNLEYKNdqwQDKKLKKTVSVLHFTA
| |.| | .. . . .. |. . |. .| . |. .| . ...|. .|. |.. .. ...|. ... .. .... ...| |.|.
PlpetieDfWrmvWeqnsavivmltqeeergkakvhryWPsk..gsrsygklvve.......lkeevelsdyvlrefkvtr...teeeesrqvrqyhyts
WPDHGAPKNPDYALDIIRFCESYK-----TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGV
|||.| |... ||..| .... . ..|||||||||||. .|.. .. | . ... .| .|. | || .| .. ... .
WpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvlleal
|
|||||||||
| subfamily_Ptp69D_pd | Subfamily Ptp69D | 941-1125 | 5.1e-23 | 76.7 | In-house | 99-280 (307) | alignment | ||
Range on Protein: 941-1125
Range on HMM: 99-280/307.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvgEKMTFGrytvttkSINTKLENFTDKKSFVMYNLEYKNDQ--WQDKKLKKTVSVLHF
| .|.. | .| . .| .. |. . | ...| | |... ... .| .|. || .. .. ... .|.. . . . . .. | |.
PveatigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie..devqyg.......dilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhy
TAWPDHGAPKNPDYALDIIRFC-ESY---KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIV
|.|.| .|. . |..|. | | .. ..|||||||||.|..||.. .| . .| . .. .|. .|. | ||| .| ..|
tgWkDskvPevargllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyr
|
|||||||||
| subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 941-1125 | 5.9e-23 | 76.3 | In-house | 100-273 (315) | alignment | ||
Range on Protein: 941-1125
Range on HMM: 100-273/315.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvgeKMTFGRYTVTTKSINTKlENFTDKkSFvmynleyknDQWQDKKLkKTVSVLHFTA
|. .... | .. ..|.| . |....| . || |. .| |...|..||| || . . ...| . .. .... ..| ||.|.
pnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk...kviyGkitvtrkseevn.teytvr.tl.........svvfgdni.revvqlhyts
WPDHGAPKNPDYALDIIRFCESYKT----SVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIV
||| | || ...|| ..| ...||||||||||||..... .. .|. .. .. ||. | ..||.|.| ..
wpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiyd
|
|||||||||
| subfamily_PTPN23_pd | Subfamily PTPN23 | 941-1134 | 1.9e-22 | 74.4 | In-house | 91-286 (288) | alignment | ||
Range on Protein: 941-1134
Range on HMM: 91-286/288.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTklenftdKKSFVMYNLEYkndQWQDKKLKKTVSVLHFTA
|..||| | .. . . .. | | | .. | . |. |. || ..|| ..|| || .. . .| ..|. . .|.. .|.|| |..|.
PlqstlnDFWlmvyeqkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvre.......tethvervlkl...etldadavksvshlqlts
WPDHGAPKNPDYALDIIRFCES--------YKTSVLVHCSAGVGRTGTLVAIKYGIQLC-TTERTTNLLSIVCPVRNCRFGAVQSAQQLMY---LIVCIT
||..|.|. |. |... || || ..|||||||||||.. . .. . . .... .| .|. | || .|| ... .
WpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaa
KGVMAK
. |. |
rrvldk
|
|||||||||
| subfamily_PTPN1_pd | Subfamily PTPN1 | 941-1132 | 2.1e-21 | 70.9 | In-house | 79-272 (290) | alignment | ||
Range on Protein: 941-1132
Range on HMM: 79-272/290.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVG-EKMTFGRYTVTTKSINTKlenftDKKSFVMYNLEYKNDQWQDkklKKTVSVLHFT
| .| . | .. . . | | |.| . | | |. .. ..... ... | |... .|. ... || .| . |. .... |.|
PlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqgeeekellledtklkvklisee.....rksyytvrllelenlktqe...treilhfhyt
AWPDHGAPKNPDYALDIIRFCE---S---YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTER---TTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKG
.||| | |. | . |. . . | . ...|||||.||.||.. . . | . . .. .. .|. |.| .| |.|| . . | .|
twpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileG
VM
.
ak
|
|||||||||
| subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 941-1124 | 1.1e-20 | 68.5 | In-house | 104-282 (305) | alignment | ||
Range on Protein: 941-1124
Range on HMM: 104-282/305.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLENFTDKKSFVMYNLEYKNDQwqdkklKKTVSVLHFTA
| |... | .. | | . |. .| | | |. |||... | . .| . . . || | || | .| |..|
pldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdq......kmsvrhlqwte
WPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTT-ERTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
||| | | .|... | ..||||||.|||||.|||.| .. . . . .| .|. | ..|. | ...
wpdrgvppckltslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfih
|
|||||||||
| 0051082 | (Phosphotyrosine protein) phosphatases II | 941-1126 | 1.2e-19 | 65.9 | In-house | 23-148 (151) | alignment | ||
Range on Protein: 941-1126
Range on HMM: 23-148/151.0
PkkstleKHWAVIDQYDVGIVAQLASVIESDdrkFAPYYSEKVGekmtfgrytvttksintklenftdkksfvmynleykndqwqdkklkKTVSVLHFTA
. ... . .... . | | | . . | | .. | .| ....
a......dflellkelgiktivnlrseeerg...ycpeylpelg..............................................ievlhipild
WPDHGAPKNPDYALDIIRFCESY-KTSVLVHCSAGVGRTGTLVAIKYGIqLCttertTNLLSIVCPVRNCRFGAVQSAQQLMYLIVC
|||.| | ..| .|........ . ||||||||.||||||||. . | .| ... .| .|.|.||. || .... .
wpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lg.....vsleealeeyrlkrpgvvqpnqqflfqlfa
|
|||||||||
| subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 941-1153 | 1.1e-18 | 62.7 | In-house | 76-275 (284) | alignment | ||
Range on Protein: 941-1153
Range on HMM: 76-275/284.0
PKKSTLEKHWAVIDQYDVGIVAQLAsviesdDRKFAPYYSEKVGEKmtFGRYTVTTKSINTKLEnftdkksFVMYNLEYKNDQWqdKKLKKTVSVLHFTA
|.. ||. | .| .|.. . |. . | . |. |. .| .|. | .|.. | .|. ..| .| .| .... ||
PldntladfWrmiweyncstivllt......kdkcsqywplkivik..eerfkvkvdsveesee.......yvvrdielsedgk..ekdirkirqfhflg
WPDHGAPKNPDYALDIIRF------CESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMAK
|||.| |. | . ... | .....|||||||||||. .... .. |. .. .| .|. | ||. | ... . . . .
wpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfg
EGVLYWRSFDAitYYHEQI
. | | |..|.
hsdvalpdfpa..yleels
|
|||||||||
| subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 941-1144 | 1.3e-17 | 58.9 | In-house | 99-301 (325) | alignment | ||
Range on Protein: 941-1144
Range on HMM: 99-301/325.0
PKKSTLEKHWAVIDQYDVGIVAqLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSIntklENFTDkksFVMYNLEYKNDQwqdKKLKKTVSVLHFTA
|. .|.. | .. .. .| . ... .. . | |. ...|. ||| | ..| |...| .|. |. |. . | ..| ... .
PltatindlWrlvldWrcsvvv.vlneldlgkdrcavywpkemgksktfGglevklrti....eeisd...yvhrvldvkqvk...kGetrsvkqfqlqs
WPDHGAPKNPDYALDIIRFCE----SY------KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKG
|.| | .| | . |.. . | .||||||||||||..... .. .| ... | .|. | |... | . . ....
wddmGvqkrpatlisilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealvea
VMAKEGVLYWRSFD
.|. . . ||.
ymsgntdvpvssfe
|
|||||||||
| subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 941-1151 | 2.3e-17 | 57.7 | In-house | 90-294 (312) | alignment | ||
Range on Protein: 941-1151
Range on HMM: 90-294/312.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEkMTFGRYTVTTKSInTKLEN---FTDKKSFVMYNLEYKNdQWQDKKLKKtvsvLH
| ..| . | . . |....| | | | |. || . . . | |.. |..| || . . .. | |. ||..
plentcthfwqlalslgstsiillcgfvedgsekcakyisdivgf.vdledhrvyteyc.teieiggkskdkithrvlkvvvka.tgqesklnh....yq
FTAWPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITKGVMAKEgv
...||||| | | || .. | |. ||||||||||||. |. | | |. . .|. | .|. | .| . |. . ...|
waswpdhgmpdscdtalrllsavkkdkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskg..
LYWRSFDAITYYHE
|| |. . | ..|
lykrneqewtkfke
|
|||||||||
| subfamily_PTPN9_pd | Subfamily PTPN9 | 941-1124 | 1.3e-14 | 48.9 | In-house | 93-283 (297) | alignment | ||
Range on Protein: 941-1124
Range on HMM: 93-283/297.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTksINTKLENFTDKKSFVMYNLEykNDQwqdkklKKTVSVLHFTA
| | | . .| .. . .| .. . |.| .| . |. .. .. . || ..|.. .... |. .......| . ... ...|. |..
plkktvsdfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsn..veveeeedykvrvleiknvk..tee......srkvthfqfls
WPDHGAPKNPDYALDIIRFCESYKT-----------------SVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYL
|||.| |.. ||... .... ..||||||.|||||.... . .. .. | .. | .|. | ..| .| ..
WPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefc
I
y
|
|||||||||
| subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 941-1127 | 1.1e-12 | 42.4 | In-house | 88-273 (287) | alignment | ||
Range on Protein: 941-1127
Range on HMM: 88-273/287.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKvGEKMTFGRYTVTTKSINTKLENFTdKKSFVMYNLEYKNdqwqdkklKKTVSVLHFTA
| .|. . | .. . . |. .. .| | |. |. | | |.|. . . | ... ... . .|| .. . | |.. .
PiaatvrdfwravletrsasvitmtreveearlkcykywPer.evPmrvGGysvvlldydikePeyg.vralrlidletre........arvvkqldlls
WPDHGAPKN----PDYALDIIRFCESYK-----TSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
|||.... ..||. .. | . ..||...|.||.|.|.|. .. . .| .|. | . ||.. || .|. .
wPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyeal
|
|||||||||
| subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 941-1123 | 1.4e-12 | 42.2 | In-house | 80-251 (267) | alignment | ||
Range on Protein: 941-1123
Range on HMM: 80-251/267.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPyysEKVGEKMTFGRYTVTtKSintkLENFTDKKSFVMYNLEYKNDQWQDkklkktVSVLHFTA
| | | ... || ...| .. | | . . |.| | |.|. . || .| ||. . . .|..||. .. |.. ..
plkntitdfltvihdqkvpvivlltkvftdnirlfwP...Pkmgqakkyqdltve.hs....lekeendyqiitlelkfknesahn......vtlyyykk
WPDHGAPK---NPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYL
| | .| ... | ..|.||.||||.||.. |. .. || .... . .|. | | |.. .. .|.
wnintnnkpylkplfgilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyi
|
|||||||||
| subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 941-1123 | 3.3e-10 | 34.0 | In-house | 102-282 (310) | alignment | ||
Range on Protein: 941-1123
Range on HMM: 102-282/310.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSeKVGEKMTFGRYTVTTKSINT-KLENFTDKKSFVMYNLEYKNDQWQDKKLKktVSVLHFT
| . |. | .| | . | | | | |. .| |.| || | . ..| .|| |. .. . |.|. ||....
plqhtiidfwrmifqeraesilllckvgeegrpkcvgywp.slgvtetygcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelr..vslikwp
AWPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYL
||| | | . ... ... . ..||||||..|....||.|. |. .. .. ... |. .|. | ...
nwpdrgvpdekchtvpqrllaqvrhgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqylii
|
|||||||||
| subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 941-1120 | 2.4e-06 | 21.8 | In-house | 13-193 (199) | alignment | ||
Range on Protein: 941-1120
Range on HMM: 13-193/199.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLEnftdkksFVMYNLEYKNDQWQdKKLKKTVSVLHFTA
| . |. | .. . | . . . .. |.. .| .||||.| || . ... | |. . .| ||.
plretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpd.......ytitaliltnntta.ppstreishyqfts
WPDHGAPKNPDYALDIIRFCES-------YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTT--NLLSIVCPVRNCRFGAVQSAQQL
| .. .|. . .. | . |.|||| | | || .||. |.. .|. .|. . .|..| | . | |.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhy
|
|||||||||
| subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 941-1120 | 2.7e-06 | 21.7 | In-house | 12-192 (198) | alignment | ||
Range on Protein: 941-1120
Range on HMM: 12-192/198.0
PKKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFGRYTVTTKSINTKLEnftdkksFVMYNLEYKNDQWQdKKLKKTVSVLHFTA
| . || | .. . | . . . .. |.. .| .||||.| || . ... | |. . .| ||.
plretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpd.......ytitaliltnntta.ppstreishyqfts
WPDHGAPKNPDYALDIIRFCES-------YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTT--NLLSIVCPVRNCRFGAVQSAQQL
| .. .|. . .. | . |.|||| | | || .||. |.. .|. .|. . .|..| | . | |.
wkekttpnvalfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhy
|
|||||||||
| subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 942-1124 | 4.9e-17 | 56.6 | In-house | 97-280 (305) | alignment | ||
Range on Protein: 942-1124
Range on HMM: 97-280/305.0
KKSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMTFG--RYTVTTKSINTKLENFTDKKSFVMYNLEYKNDQWQDKKLKktVSVLHFT
. | | . | | . | ..| .| . |.. | .....| .. | .. .|... . .. . . . |..| |. |.
lektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekark..vthyhwi
AWPDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVAIKYGI-QLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
||| | | |... . . | . ||||||.||||..| ..| . || . . . |. .|. | ..|. .| ...
dwpdrgvpaadlailellekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvh
|
|||||||||
| subfamily_PTPN6_pd | Subfamily PTPN6 | 943-1129 | 4.7e-23 | 76.6 | In-house | 108-295 (306) | alignment | ||
Range on Protein: 943-1129
Range on HMM: 108-295/306.0
KSTLEKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGEKMtFGRYTVTTKSINtklenftDKKSFVMYNLEYKNDqwQDKKLKKTVSVLHFTAWP
..|.. | .. | . .. . .| | |.|. .. ... .|...||. | . ....... .| .. ..|| ...| .||..||
ettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekee.yGkisvtnvsek.......sladYilRelsvskk..kkkkeerevfqyhfksWP
DHGAPKNPDYALDIIR----FCESYK----TSVLVHCSAGVGRTGTLVAIKYGIQLCTT---ERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCITK
||| ||.|. || .. |. . ...||||||.|||||.. | ..| .. . ... ..| ||. | | || .|| .. |.|
dhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikk
|
|||||||||
| 0051429 | (Phosphotyrosine protein) phosphatases II | 944-1129 | 7.1e-24 | 80.3 | In-house | 33-223 (272) | alignment | ||
Range on Protein: 944-1129
Range on HMM: 33-223/272.0
STLEKHWAViDQYDVGIVAQLASVIESDDRKFAPYYS----------EKVGEKMTFGRYTVTTKSINTKLEnftdkksFVMYNLEYKNDQWQDKKlkKTV
| . |. .... . | |. | . |. .| . . . ...|...||. |. ..| .....|.... .. .|
ltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld.......yilrellltlllsagea..rev
SVLHFTAWPDHGAPKNPdyALDIIRFCESyKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTN--------LLSIVCPVRNCRFGAVQSAQQLMYLIV
.||.|.|||||.|... |...... . . ||||||||..||||.||. . .. . | . |. .| .| .| ||||. .|...|
mhlhytdwpdhgvpqea..llellellld.ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflye
CITK
.. .
alle
|
|||||||||
| 0044763 | (Phosphotyrosine protein) phosphatases II | 947-1126 | 9.5e-20 | 66.4 | In-house | 38-166 (178) | alignment | ||
Range on Protein: 947-1126
Range on HMM: 38-166/178.0
EKHWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGekmtfgrytvttksintklenftdkksfvmynleykndqwqdkklkktvSVLHFTAWPDHGA
..... . ..... . |.. .| | ||. |. | ... .||||.
addlellkelgithivnlteelelgflkcdpywpeeag.................................................iqylhipipDhgv
PKNPDYALDIIRFCE----SYKTSVLVHCSAGVGRTGTLVAIKYGIQLctterTTNLLSIVCPVRNCRFgAVQSAQQLMYLIVC
| ... |....|.| . . |||||||||||.|||||. . ..| .| ... ||..|. .|.. || .|. .
pdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrerRp.ivpnpgqlrqLyef
|
|||||||||
| subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 949-1126 | 4.3e-12 | 40.7 | In-house | 67-235 (239) | alignment | ||
Range on Protein: 949-1126
Range on HMM: 67-235/239.0
HWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGeKmtFGRYTVTTKsintKLENFTDK--KSFVMYNLEYKNDqwqdkklkKTVSVLHFTAWPDHGA
| .. | .. |. .|| .| |. . | . || . | | |.| ..||| .. .. . | ||| |||.|
fwrmmwqerrcvivmltglieghkkkchqywpdsts.k..ycnlrvtlr....ktevfadyiirtfvmsqvgqtee........ryvyqyhftvwpdkgv
PKNPDYALDIIRFCE--SY--KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVC
|. | . | | ..||||||||||... | .. . ..| ... | .|. | ||...| ... ..
pqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihla
|
|||||||||
| subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 949-1125 | 5.1e-12 | 40.5 | In-house | 68-235 (239) | alignment | ||
Range on Protein: 949-1125
Range on HMM: 68-235/239.0
HWAVIDQYDVGIVAQLASVIESDDRKFAPYYSEKVGeKmtFGRYTVTTKsintKLENFTDK--KSFVMYNLEYKNDqwqdkklkKTVSVLHFTAWPDHGA
| .. | .. |. .|| .| |. . | . || . | | |.| ..||| .. .. . | ||| |||.|
fwrmmwqerrcvivmltglieghkkkchqywpdsts.k..ycnlrvtlr....ktevfadyiirtfvmsqvgqtee........ryvyqyhftvwpdkgv
PKNPDYALDIIRFCE--SY--KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIV
|. | . | | ..||||||||||... | .. . ..| ... | .|. | ||...| ... .
pqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihl
|
|||||||||
| 0048076 | (Phosphotyrosine protein) phosphatases II | 983-1127 | 1.9e-21 | 71.7 | In-house | 7-139 (145) | alignment | ||
Range on Protein: 983-1127
Range on HMM: 7-139/145.0
VGEKMTFGRYTVTTKsintkLENFTDKKSFVMYNLeykndQWQDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESY---KTSVLVHCSAGVGRTG
. ... .| .... . ||.. | . .|| . |.... .... |||||.| ... |....|.|.. . |||||||||||||
ilpglylgslptald.....lellkdlgittvlnl.....tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtg
TLVAIKYGIQlctteRTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCI
||||. .. . .| ... ||..|.|||.. .|| .|. ..
tlvaaylmll.....lgvsleealelvrsqrpgavpnpgqlrflyefe
|
|||||||||
| PTEN_1 | 998-1083 | 2.4e-08 | 29.0 | In-house | 55-149 (196) | alignment | |||
Range on Protein: 998-1083
Range on HMM: 55-149/196.0
SINTKLENFTDKKSFVMYNLEYKNDQ----WQDKK-LKKTVSVLHFtAWPDHGAPKnPDYALDIIRFCESY------KTSVLVHCSAGVGRTGTLVA
.. |.|. .. . .||. . . ..... |. |..||| ..||||| . .||.. .... . ||||| ||.||.||.||
dvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhf.pieDhgaps.lselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvva
|
|||||||||
| subfamily_PTEN_pd | Subfamily PTEN | 999-1122 | 8.8e-07 | 24.1 | In-house | 50-171 (184) | alignment | ||
Range on Protein: 999-1122
Range on HMM: 50-171/184.0
INTKLENFTdKKSFVMYNLEyKNDQWQDKKLKKTVSVLHFTawpDHGAPKNP---DYALDIIRFCESYKT-SVLVHCSAGVGRTGTLVAiKYGIQLCTTE
. ||. |... .||| . ... ||... |.|. |. || .|. . || .. |. |. | ||| || ||||.|.. | .. ...|
vvkflekkh.kdhykiynlr.serkydskkfdgrvavypfd...DhnppplelleeivediekwleedkknvvvvHCkaGkGRtGvliv.ayllksllle
RTTNLLSIVCPVRNCRFGAVQSAQQLMY
.... |.. .| .|. |. |
kaeealelfaeaRtknkkgvtiPsqrRY
|
|||||||||
| 0038934 | (Phosphotyrosine protein) phosphatases II | 1007-1125 | 3.4e-12 | 41.9 | In-house | 53-171 (194) | alignment | ||
Range on Protein: 1007-1125
Range on HMM: 53-171/194.0
TDKKSFVMYNLEYKNDQWQDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCES-----YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTterttNLLS
.| . ..| . . . ....| . .||.|.. . . |....... . |.||| ||.|||||||| |. ..
lnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgm.....saee
IVCPVRNCRFGAVQSAQQLMYLIV
. .| .| ||... ..| .| .
AialfrekRpgaipnqdyleallk
|
|||||||||
| 0048567 | (Phosphotyrosine protein) phosphatases II | 1017-1084 | 9.2e-07 | 23.4 | In-house | 21-97 (157) | alignment | ||
Range on Protein: 1017-1084
Range on HMM: 21-97/157.0
LEYKNDQWQDKKLKKTVSVLHFTAWPDHGaPKNP-------DYALDIIRFCESYKTSVLVHCSAGV---GRTGTLVAI
..... . . . . ..... . |.| | | .. ......| . . |||.|| |||.||..
prlpkslynalyFsiddglvyedfffdfG.PlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigc
|
|||||||||
| subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1018-1161 | 2.5e-12 | 40.9 | In-house | 76-221 (440) | alignment | ||
Range on Protein: 1018-1161
Range on HMM: 76-221/440.0
EYKNDQWQDKKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCE-S----YKTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFG
.| | . . .|. |. .|||.| || | .|. . | . .|||||||.|||| ..|. .. . ...|.. .|| |
dyinasyingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpq
AVQSAQQLMYLIVCITKGVMAKEGVLYwrsFDAITYYHEQILADKYHDN
||. .| .. .. .|... . .. | || ||| . | .
mvqtpeqyafvheavlegllcgdtlil...edditerveqiqwpnphtd
|
|||||||||
| 0048179 | (Phosphotyrosine protein) phosphatases II | 1027-1124 | 1.2e-20 | 69.2 | In-house | 43-138 (144) | alignment | ||
Range on Protein: 1027-1124
Range on HMM: 43-138/144.0
KKLKKTVSVLHFTAWPDHGAPKNPDYALDIIRFCESY---KTSVLVHCSAGVGRTGTLVAIKygiqLCTTERtTNLLSIVCPVRNCRFGAVQSAQQLMYL
|.... .... |||||.| ... |....|.|.. . |||||||||||||||||. |. ... .| ... ||..|.|||.. .||..|
efleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaay....lmkklg.lsleealalvrsrrpgavpnpgqlrfL
I
.
l
|
|||||||||
| subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1031-1121 | 5.9e-08 | 27.3 | In-house | 81-166 (182) | alignment | ||
Range on Protein: 1031-1121
Range on HMM: 81-166/182.0
KTVSvLHFTAWPDHGAPkNPDYALDIIRFCESY--KTSVLVHCSAGVGRTGTLVAIkYgiqLCTTERTTNLlSIVCPVRNCRFGAVQSAQQLM
. . . .|.|.|.. . .|||.. .. . | ||| || |||| |.| | | ..| | . ||. | ..|. .|.
qgiy.vynfgwkDygva.sleriLdivkvvafalqegkvavhChaGlGrtGvliac.y...lvyakrltae.kaiklvrskrpksiqtreqve
|
|||||||||
| PTPc_DSPc_SM00012 | 1032-1127 | 7.7e-25 | 82.5 | In-house | 1-103 (105) | alignment | |||
Range on Protein: 1032-1127
Range on HMM: 1-103/105.0
TVSVLHFTAWPDHGAPKNPDYALDIIRFCESYKT------SVLVHCSAGVGRTGTLVAIKYGIQLCTTE-RTTNLLSIVCPVRNCRFGAVQSAQQLMYLI
||...|.|.|||||.|...| |...| ... |. .|.||||||||||||.||. . .| ...| .. ... ||. .|. | |.||. .| ..|.
tvkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfly
VCI
..
ral
|
|||||||||
| DSPc | Dual specificity phosphatase, catalytic domain | 1042-1083 | 2.3e-07 | 25.8 | Pfam-A | 51-92 (133) | alignment | ||
Range on Protein: 1042-1083
Range on HMM: 51-92/133.0
PDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVA
. | . | ..|. .|. . .||||| ||. |..||..
tetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatlii
|
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| DSPc | Dual specificity phosphatase, catalytic domain | 1042-1083 | 2.3e-07 | 25.8 | In-house | 51-92 (133) | alignment | ||
Range on Protein: 1042-1083
Range on HMM: 51-92/133.0
PDHGAPKNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVA
. | . | ..|. .|. . .||||| ||. |..||..
tetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatlii
|
|||||||||
| PTPc_motif_SM00404 | 1048-1083 | 6.7e-08 | 27.5 | In-house | 64-99 (140) | alignment | |||
Range on Protein: 1048-1083
Range on HMM: 64-99/140.0
KNPDYALDIIRFCESYKTSVLVHCSAGVGRTGTLVA
| | .||.|. .|. ...||||| ||| |..||..
kyldkvldfienaekkggkvlVHCqaGvSRSatlii
|
|||||||||
| subfamily_CDC14_pd | Subfamily CDC14 | 1054-1120 | 2.1e-08 | 28.4 | In-house | 253-314 (328) | alignment | ||
Range on Protein: 1054-1120
Range on HMM: 253-314/328.0
LDIIRFCESYKTSVLVHCSAGVGRTGTLVAIkYgiqLCTTERTTNlLSIVCPVRNCRFGAVQSAQQL
.. .|. . .. ||| ||.||||||.| | | . | | .. .| || | | . ||
kkfleiaekaeGaiavhCkaGLGrtGtLiac.y...lmkhyrfta.aeaiawlricrPGsvigpqqk
|
|||||||||
| subfamily_PRL_pd | Subfamily PRL | 1054-1123 | 3.5e-06 | 21.1 | In-house | 78-142 (151) | alignment | ||
Range on Protein: 1054-1123
Range on HMM: 78-142/151.0
LDI--IRFCESYKTSVLVHCSAGVGRTGTLVAIKYgiqlctTERTTNLLSIVCPVRNCRFGAVQSaQQLMYL
|.. .|.|. |..| ||| ||.||. |||. | . | .|. | ||. | .|| .|
lellkekfkeepkstvavhcvaGlGraPvlvalal......ieaGmkyedavefirekrrgains.kqlkfl
|
|||||||||
| subfamily_CG42327_pd | Subfamily CG42327 | 1064-1123 | 8.6e-09 | 29.5 | In-house | 247-307 (319) | alignment | ||
Range on Protein: 1064-1123
Range on HMM: 247-307/319.0
KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTE-RTTNLLSIVCPVRNCRFGAVQSAQQLMYL
. . |||| ||||||...| |. . |. .. .| ||. | ||.. .| ..
qGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefi
|
|||||||||
| subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1064-1128 | 3e-07 | 24.6 | In-house | 228-292 (297) | alignment | ||
Range on Protein: 1064-1128
Range on HMM: 228-292/297.0
KTSVLVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYLIVCIT
.. .||||||||||.| .| . .. .| . .|. .|. | ||. .| .| .
nayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavl
|
|||||||||
| subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1068-1121 | 2.4e-06 | 21.8 | In-house | 2-55 (69) | alignment | ||
Range on Protein: 1068-1121
Range on HMM: 2-55/69.0
LVHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLM
.||||.| |||||..|| . .|. ... | .| || | .. .
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyi
|
|||||||||
| subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1069-1123 | 1.8e-06 | 22.2 | In-house | 2-56 (69) | alignment | ||
Range on Protein: 1069-1123
Range on HMM: 2-56/69.0
VHCSAGVGRTGTLVAIKYGIQLCTTERTTNLLSIVCPVRNCRFGAVQSAQQLMYL
||||.| |||||..|| . .|. ... | .| || | . |..
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfi
|
|||||||||